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At least 883 records · Page 49

Extinction Imaging Diagnostics for In Situ Quantification of Soot within Explosively Generated Fireballs

Fireballs produced from the detonation of high explosives often contain particulates primarily composed of various phases of carbon soot. The transport and concentration of these particulates is of interest for model validation and emission characterization. Here, this work proposes ultra-high-speed imaging techniques to observe a fireball's structure and optical depth. An extinction-based diagnostic applied at two wavelengths indicates that extinction scales inversely with wavelength, consistent with particles in the Rayleigh limit and dimensionless extinction coefficients which are independent of wavelength. Within current confidence bounds, the extinction-derived soot mass concentrations agree with expectations based upon literature reported soot yields. Results also identify areas of high uncertainty where additional work is recommended.

33 ADVANCED PROPULSION SYSTEMS↗

Noninvasive Techniques for Intracranial Pressure Assessment: A Review from Aerospace Medicine Perspective

Microgravity-induced changes in fluid distribution and other physiological factors due to space flight have been implicated as the cause of increased intracranial pressure (ICP) in a number of space crewmembers. The modest levels of ICP elevation and absence of severe symptoms in this group do not warrant invasive diagnostic interventions. However, the long-term trends and residual or consequential changes secondary to the observed ICP elevation in this group are not yet known. Therefore, close attention is needed to evaluate the potential techniques of noninvasively assessing ICP, including those feasible for in-flight use. Of particular interest is continuity between ground and in-flight testing, whereby data from the same or different techniques allow reasonably dependable estimation of ICP trends and responses. Methods: A thorough review of current literature, analysis of NASA data, and interviews with subject matter experts were conducted to construct a presentation that reflects the state of the art for noninvasive ICP measurement and monitoring. Results: Multiple imaging and non-imaging modalities are available to assess ICP in terrestrial clinical and experimental environments. Imaging alternatives include magnetic resonance imaging (MRI) and high-resolution sonography. Non-imaging techniques include transcranial Doppler, certain audiological methods, and venous ophthalmodynamometry, among others. Special functional techniques have been proposed recently that allow the use of advanced MRI methods to calculate ICP in addition to the acquisition of high-resolution images. Our data include many of these applications, with several cases of correlation with lumbar puncture, the invasive "gold standard" measurement of ICP.

Hamilton, Douglas R.↗

Clementine: Anticipated scientific datasets from the Moon and Geographos

The Clementine spacecraft mission is designed to test the performance of new lightweight and low-power detectors developed at the Lawrence Livermore National Laboratory (LLNL) for the Strategic Defense Initiative Office (SDIO). A secondary objective of the mission is to acquire useful scientific data, principally of the Moon and the near-Earth asteroid Geographos. The spacecraft will be in an elliptical polar orbit about the Moon for about 2 months beginning in February of 1994 and it will fly by Geographos on August 31. Clementine will carry seven detectors each weighing less than about 1 kg: two Star Trackers wide-angle uv/vis wide-angle Short Wavelength IR (SWIR) Long-Wavelength IR (LWIR) and LIDAR (Laser Image Detection And Ranging) narrow-angle imaging and ranging. Additional presentations about the mission detectors and related science issues are in this volume. If fully successful Clementine will return about 3 million lunar images, a dataset with nearly as many bits of data (uncompressed) as the first cycle of Magellan and more than 5000 images of Geographos. The complete and efficient analysis of such large data sets requires systematic processing efforts. Described below are concepts for two such efforts for the Clementine mission: global multispectral imaging of the Moon and videos of the Geographos flyby. Other anticipated datasets for which systematic processing might be desirable include multispectral observations of Earth; LIDAR altimetry of the Moon with high-resolution imaging along each ground track; high-resolution LIDAR color along each lunar ground track which could be used to identify potential titanium-rich deposits at scales of a few meters; and thermal IR imaging along each lunar ground track (including nighttime observations near the poles).

Mcewen, A. S.↗

Three-Dimensional Imaging and Numerical Reconstruction of Graphite/Epoxy Composite Microstructure Based on Ultra-High Resolution X-Ray Computed Tomography

A combined experimental and computational study aimed at high-resolution 3D imaging, visualization, and numerical reconstruction of fiber-reinforced polymer microstructures at the fiber length scale is presented. To this end, a sample of graphite/epoxy composite was imaged at sub-micron resolution using a 3D X-ray computed tomography microscope. Next, a novel segmentation algorithm was developed, based on concepts adopted from computer vision and multi-target tracking, to detect and estimate, with high accuracy, the position of individual fibers in a volume of the imaged composite. In the current implementation, the segmentation algorithm was based on Global Nearest Neighbor data-association architecture, a Kalman filter estimator, and several novel algorithms for virtualfiber stitching, smoothing, and overlap removal. The segmentation algorithm was used on a sub-volume of the imaged composite, detecting 508 individual fibers. The segmentation data were qualitatively compared to the tomographic data, demonstrating high accuracy of the numerical reconstruction. Moreover, the data were used to quantify a) the relative distribution of individual-fiber cross sections within the imaged sub-volume, and b) the local fiber misorientation relative to the global fiber axis. Finally, the segmentation data were converted using commercially available finite element (FE) software to generate a detailed FE mesh of the composite volume. The methodology described herein demonstrates the feasibility of realizing an FE-based, virtual-testing framework for graphite/fiber composites at the constituent level.

Czabaj, M. W.↗

Influence of Fault-Controlled Topography on Fluvio-Deltaic Sedimentary Systems in Eberswalde Crater, Mars

Eberswalde crater was selected as a candidate landing site for the Mars Science Laboratory (MSL) mission based on the presence of a fan-shaped sedimentary deposit interpreted as a delta. We have identified and mapped five other candidate fluvio -deltaic systems in the crater, using images and digital terrain models (DTMs) derived from the Mars Reconnaissance Orbiter (MRO) High Resolution Imaging Science Experiment (HiRISE) and Context Camera (CTX). All of these systems consist of the same three stratigraphic units: (1) an upper layered unit, conformable with (2) a subpolygonally fractured unit, unconformably overlying (3) a pitted unit. We have also mapped a system of NNE-trending scarps interpreted as dip-slip faults that pre-date the fluvial -lacustrine deposits. The post-impact regional faulting may have generated the large-scale topography within the crater, which consists of a Western Basin, an Eastern Basin, and a central high. This topography subsequently provided depositional sinks for sediment entering the crater and controlled the geomorphic pattern of delta development.

Rice, Melissa S.↗

Enhancing Diagnosis through AI-driven Analysis of Reflectance Confocal Microscopy

Reflectance Confocal Microscopy (RCM) is a non-invasive imaging technique used in biomedical research and clinical dermatology. It provides virtual high-resolution images of the skin and superficial tissues, reducing the need for physical biopsies. RCM employs a laser light source to illuminate the tissue, capturing the reflected light to generate detailed images of microscopic structures at various depths. Recent studies explored AI and machine learning, particularly CNNs, for analyzing RCM images. Our study proposes a segmentation strategy based on textural features to identify clinically significant regions, empowering dermatologists in effective image interpretation and boosting diagnostic confidence. This approach promises to advance dermatological diagnosis and treatment.

Yoon, Hong-Jun↗

Space and time resolved emission of hard X-rays from a plasma focus

The X-ray emission from focused plasmas was observed with an image converter camera in the streak and framing modes. Use of a very high gain image intensifier enabled weak hard X-ray emission (above 25 keV) to be recorded. The use of an admixture of higher atomic number into the deuterium was avoided, and the role of the vapor from the anode surface could be discerned. The recorded bremsstrahlung emission seemed to be from a metallic plasma of copper released from the anode surface by bombardment from an intense electron beam. The intensity of emission was determined by the density of copper and the density and energy of the electron beam. The main emission recorded occurred several 100 nsec after the focus was over, which implies that the electric fields driving the beam existed for this duration. It is suggested that the fields were created by annihilation of magnetic flux for a time much longer than the focus duration.

Harries, W. L.↗

X-ray variability in active galaxy nuclei and quasars in less than one day

Data obtained from the Einstein Observatory demonstrating variations in X-ray emission from the nuclei of active galaxies and quasars on time scales of hours rather than previously observed days or years is presented. Light curves obtained from the Einstein imaging proportional counter for the Seyfert 1 galaxy NGC 6814 and from the High Resolution Imager for the quasars OX 169 and 3C 273 are illustrated, and variations by factors greater than two on time scales less than 20,000 sec for the first two objects and by a factor of 10% on a time scale over 50,000 sec for 3C 273 are pointed out. The measurements are also used to determine that thermal bremsstrahlung cannot be the cause of the intensity decay in OX 169, and that, in the absence of relativistic effects, the efficiency for energy release in the matter involved in the emission of 3C 273 is at least 0.1.

Elvis, M.↗

Recent progress with multi-anode microchannel array detector systems

The construction and modes of operation of Multi-Anode Microchannel Arrays (MAMA's) are briefly reviewed. The MAMA detectors, which are a family of photoelectric, photon-counting array detectors being developed specifically for use in instruments on ground-based and space-borne telescopes, combine the high sensitivity and photometric stability of a conventional channel electron multiplier with a high-resolution imaging capability. The MAMA detectors feature low applied potential (less than 3 kV), high gain (greater than 10 to the 6th electrons/pulse), an absolute event timing accuracy of 100 ns or better, a very long count lifetime (greater than 2.5 x 10 to the 11th counts/sq mm), and a power consumption of less than 30 W for a complete system

Timothy, J. G.↗

Gravitational lensing by a smoothly variable surface mass density

The statistical properties of gravitational lensing due to smooth but nonuniform distributions of matter are considered. It is found that a majority of triple images had a parity characteristic for 'shear-induced' lensing. Almost all cases of triple or multiple imaging were associated with large surface density enhancements, and lensing objects were present between the images. Thus, the observed gravitational lens candidates for which no lensing object has been detected between the images are unlikely to be a result of asymmetric distribution of mass external to the image circle. In a model with smoothly variable surface mass density, moderately and highly amplified images tended to be single rather than multiple. An opposite trend was found in models which had singularities in the surface mass distribution.

Paczynski, Bohdan↗

Mapping alteration in the Goldfield Mining District, Nevada, with the Airborne Visible/Infrared Imaging Spectrometer (AVIRIS)

Analysis of the data acquired by the Airborne Visible/IR Imaging Spectrometer over the Goldfield Mining District, Nevada, demonstrates the unique capabilities of high resolution imaging spectrometers for alteration mapping and identification of mineralogy. The study focuses on the 2-2.45 micron window, as alteration minerals of interest have their distinctive spectral reflectance features in this region. An attempt was made to map the spatial distribution of the individual minerals and produce a mixture maps showing their relative abundance on a pixel-by-pixel basis, focussing on selected subareas. Software and SNR performances limited success in detailed mapping.

Carrere, Veronique↗

HRI observations of the Pleiades

The preliminary analysis of the data from the first four Rosat high resolution imager (HRI) pointings provided many new faint Pleiades detections. The completion of the high resolution survey of the most source-confused regions of this open cluster will lead to the construction of proper X-ray luminosity functions and will yield a definitive assessment of the coronal emission of the Pleiades members.

Harnden, F. R., Jr.↗

A New Method to Resolve X-Ray Halos around Point Sources with Chandra Data and Its Application to Cygnus X-1

With excellent angular resolution, good energy resolution, and a broad energy band, the Chandra Advanced CCD Imaging Spectrometer (ACIS) is the best instrument for studying the X-ray halos around some Galactic X-ray point sources caused by the dust scattering of X-rays in the interstellar medium. However, the direct images of bright sources obtained with the ACIS usually suffer from severe pileup. Making use of the fact that an isotropic image could be reconstructed from its projection in to any direction, we can reconstruct the images of the X-ray halos from the data obtained with the High Energy Transition Grating Spectrometer (HETGS) and/or in continuos clocking (CC) mode. These data have no or less serious pileup and enable us to take full advantage of the excellent angular resolution of Chandra. With the reconstructed high-resolution images, we can probe the X-ray halos as close as 1" to their associated point sources. Applying this method to Cygnus X-1 observed with the Chandra HETGS in CC mode, we derived an energy-dependent radial halo flux distribution and concluded that in a circular region (2' in radius) centered a the point source: (1) relative to the total intensity, the fractional halo intensity is about 15% at keV and drops to aboout 5% at approximately 6 keV (2) about 50% of the halo photons are within the region of a radius less than 40 inches and (3) the spectrum of the pooint source is slightly distorted by the halo contamination.

Yao, Yangsen↗

Sources of and Remedies for Removing Unwanted Reflections in Millimeter Wave Images of Complex SOFI-Covered Structures

In the recent years, continuous-wave (CW) near-field and lens-focused millimeter wave imaging systems have been effectively. used to demonstrate their utility for producing high-resolution images of metallic structures covered with spray on foam insulation (SOFI) such as the space shuttle external tank. These systems have produced images with a spatial resolution of approximately 2 mm at a frequency of 150 GHz, and can easily interrogate thin as well as thick SOFI (> 9") enabling detection and evaluation of flaws such as voids, disbands, delaminations and corrosion. These systems are relatively simple, inexpensive, easy-to-use, require little to no signal processing of the raw data, on-site friendly, real-time and small. However, for some specific structures a certain interference pattern may be superimposed on the produced images. Generally, this occurs when the SOFI surface is at a relatively significant angle with respect to the surface of the substrate (or other sub-structures) on which it is sprayed. Consequently, the reflection from the surface of the SOFI and that from the substrate (or sub-structure) coherently combine into an interference pattern as the SOFI surface is scanned. There are methods by which the influence of this unwanted interference can be reduced, such as the incorporation of an incidence angle and the proper use of signal polarization. This paper presents the basics of this problem and describes the use of the methods for reducing this unwanted influence through several specific examples. A discussion on how the use of a swept-frequency or pulsed method may also alleviate this problem is also presented.

Khakovsky, S.↗

Sources of and Remedies for Removing Unwanted Reflections in Millimeter Wave Images of Complex SOFI-Covered Space Shuttle Structures

In the recent years, continuous-wave near-field and lens-focused millimeter wave imaging systems have been effectively used to demonstrate their utility for producing high-resolution images of metallic structures covered with spay on foam insulation (SOFI) such as the Space Shuttle external fuel tank. However, for some specific structures a certain interference -pattern may be superimposed on the produced images. There are methods by which the influence of this unwanted interference can be reduced, such as the incorporation of an incidence .angle and the proper use of signal polarization. This paper presents the basics of this problem and describes the use of the methods for reducing this unwanted influence through specific examples.

Kharkovsky, S.↗

Calibrating Optical Distortions in the Solar Orbiter SPICE Spectrograph

The Spectral Imaging of the Coronal Environment (SPICE) instrument on Solar Orbiter is a high-resolution imaging spectrometer operating at extreme ultraviolet (EUV) wavelengths from 70.4-79.0 nm and 97.3-104.9 nm. A single-mirror off-axis paraboloid focuses the solar image onto the entrance slit of the spectrometer section. A Toroidal Variable Line Space (TVLS) grating images the entrance slit onto a pair of MCP-intensified APS detectors. Ray-tracing analysis prior to launch showed that the instrument was subject to a number of small image distortions which need to be corrected in the final data product. We compare the ray tracing results with measurements made in flight. Co-alignment with other telescopes on Solar Orbiter will also be examined.

Therese Ann Kucera↗

In search of random noise

In order to make the best high resolution images of IRAS data it is necessary to incorporate any knowledge about the instrument into a model: the IRAS model. This is necessary since every remaining systematic effect will be amplified by any high resolution technique into spurious artifacts in the images. The search for random noise is in fact the never-ending quest for better quality results, and can only be obtained by better models. The Dutch high-resolution effort has resulted in HIRAS which drives the MEMSYS5 algorithm. It is specifically designed for IRAS image construction. A detailed description of HIRAS with many results is in preparation. In this paper we emphasize many of the instrumental effects incorporated in the IRAS model, including our improved 100 micron IRAS response functions.

Kester, DO↗

Fully Integrated Ultra-thin Intraoperative Micro-imager for Cancer Detection Using Upconverting Nanoparticles

Abstract Purpose Intraoperative detection and removal of microscopic residual disease (MRD) remain critical to the outcome of cancer surgeries. Today’s minimally invasive surgical procedures require miniaturization and surgical integration of highly sensitive imagers to seamlessly integrate into the modern clinical workflow. However, current intraoperative imagers remain cumbersome and still heavily dependent on large lenses and rigid filters, precluding further miniaturization and integration into surgical tools. Procedures We have successfully engineered a chip-scale intraoperative micro-imager array—without optical filters or lenses—integrated with lanthanide-based alloyed upconverting nanoparticles (aUCNPs) to achieve tissue imaging using a single micro-chip. This imaging platform is able to leverage the unique optical properties of aUCNPs (long luminescent lifetime, high-efficiency upconversion, no photobleaching) by utilizing a time-resolved imaging method to acquire images using a 36-by-80-pixel, 2.3 mm $$\times$$ × 4.8 mm silicon-based electronic imager micro-chip, that is, less than 100-µm thin. Each pixel incorporates a novel architecture enabling automated background measurement and cancellation. We have validated the performance, spatial resolution, and the background cancellation scheme of the imaging platform, using resolution test targets and mouse prostate tumor sample intratumorally injected with aUCNPs. To demonstrate the ability to image MRD, or tumor margins, we evaluated the imaging platform in visualizing a single-cell thin section of the injected prostate tumor sample. Results Tested on USAF resolution targets, the imager is able to achieve a resolution of 71 µm. We have also demonstrated successful background cancellation, achieving a signal-to-background ratio of 8 when performing ex vivo imaging on aUCNP-injected prostate tumor sample, improved from originally 0.4. The performance of the imaging platform on single-cell layer sections was also evaluated and the sensor achieved a signal-to-background ratio of 4.3 in resolving cell clusters with sizes as low as 200 cells. Conclusion The imaging system proposed here is a scalable chip-scale ultra-thin alternative for bulky conventional intraoperative imagers. Its novel pixel architecture and background correction scheme enable visualization of microscopic-scale residual disease while remaining completely free of lenses and filters, achieving an ultra-miniaturized form factor—critical for intraoperative settings.

59 BASIC BIOLOGICAL SCIENCES↗