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Search indexed NASA NTRS and DOE OSTI research on propulsion, heat transfer, battery materials and energy systems. Follow report and document links to the original sources.

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At least 883 records · Page 49
All sourcesNASA NTRSDOE OSTI
DOE OSTI2018

Microbial consortia for programmable output via photoautotroph-heterotroph interactions

Self-sustained, safe, stable and scalable microbial consortia (S 5 MicroCon) are described. The microbial consortia are regulated by photoautotroph-heterotroph interactions and RNA aptamer-based gene circuits. A rapid, high-throughput method for engineering RNA aptamer-based gene circuits (e.g. riboswitches) is also described.

59 BASIC BIOLOGICAL SCIENCES↗
DOE OSTI2019

Field programmable gate array bitstream verification

Described herein are various technologies pertaining to confirming an integrity of a FPGA. A verifier circuit is placed into an FPGA bitstream to enable external verification of the FPGA configuration in real time without requiring readout of the FPGA configuration itself. Number generators are utilized to generate a key which is shared between the FPGA and an external verification component (VC). The key is utilized to configure an initial state of sequence registers respectively located on both the FPGA and the VC. When the FPGA is operating with an approved configuration, output from the sequence registers at the FPGA and the VC are the same.

38 RADIATION CHEMISTRY, RADIOCHEMISTRY, AND NUCLEA↗
DOE OSTI2020

Methods of designing programmable inducible promoters

Described herein is a method for identifying synthetic inducible promoters that have specified induction and/or repression for DNA binding proteins such as an allosteric transcription factor and an inducer molecule. The method includes an in vitro selection from an unselected polynucleotide library comprising a plurality of random degeneracies, and an in vivo selection to produce an induced promoter library. Produced is an induction table, which allows the selection of a promoter with specific induction and/or repression properties. Also included are biosensors containing the synthetic inducible promoters.

37 INORGANIC, ORGANIC, PHYSICAL, AND ANALYTICAL CH↗
DOE OSTI2021

Wireless optofluidic systems for programmable in vivo pharmacology and optogenetics

Provided are implantable, injectable and/or surface mounted biomedical devices and related methods for interfacing with a target tissue. The devices have a substrate, one or more microfluidic channels embedded in or supported by the substrate and a fluid actuator in operational communication with one or more reservoirs and responsive to a wireless control signal. The components of the device are specially configured and packaged to be ultra-thin and mechanically compliant. In some embodiments, the devices are self-powered and fully implantable. The devices can be shaped to provide injection in a minimally invasive manner, thereby avoiding unnecessary tissue damage and providing a platform for long-term implantation for interfacing with biological tissue.

Rogers, John A.↗
DOE OSTI2022

Programmable pseudo-random sequence generator for use with universal lidar and its associated method of operation

A pseudo-random sequence generator for use within a universal lidar system and its corresponding method of operation. The pseudo-random sequence generator uses synchronized shift registers that are in series Binary adders are provided. The signal output of each of the shift registers is tapped and directed to the binary adders. High-speed switches are provided between the shift registers and the binary adders. The switches are programmed to connect only two of the shift registers to the binary adders for each of the pseudo-random patterns being generated. The binary adders generate an output signal that is received by the first shift register. The signal propagates through all the shift registers to the last shift register. The last shift register outputs a pseudo-random sequence.

Datta, Shubhashish↗
DOE OSTI2017

Recent Developments in the United Kingdom Geological Disposal Facility Programme - 17558

The United Kingdom Government remains committed to the policy of geological disposal. All major nuclear nations are actively pursuing geological disposal. It is internationally recognised that geological disposal represents the safest and most sustainable option as the end point of the management of high level waste and spent fuel considered as waste. Other countries that have also decided on a policy of geological disposal include Canada, Finland, France, Switzerland, Sweden and the United States of America. The United Kingdom Government continues to favour an approach to siting a Geological Disposal Facility that is based on the willingness of local communities to participate in the siting process. Construction and operation of a Geological Disposal Facility will be a multi-billion pound project that will provide skilled employment for hundreds of people over many decades. It will contribute greatly to the local economy and wider socio-economic framework. There are also likely to be spin-off industry benefits, infrastructure investments, benefits to local education or academic resources, and positive impacts on local service industries that support the facility and its workforce. It is also likely to involve major investments in local transport facilities and other infrastructure, which would remain after the facility had been closed. The United Kingdom Government published a renewed process for siting a Geological Disposal Facility in 2014 - the Implementing Geological Disposal White Paper. This paper discusses the status of activities in the 2014 White Paper that have been accomplished or are underway through to 2016. (authors)

12 MANAGEMENT OF RADIOACTIVE AND NON-RADIOACTIVE W↗
DOE OSTI2015

Challenges of mine remediation programmes in developing countries - a life cycle perspective - 15371

This paper analyses some challenges of environmental rehabilitation (ER) projects in developing countries that the authors have encountered over the past two decades in many parts of the world, discusses the reasons and proposes ways to mitigate them. In the life cycle of an ER project, some stages that are particularly decisive for the lasting rehabilitation success are considered here: (1) site characterisation/baseline studies, (2) justification and development of remediation objectives, site end states and a remediation strategy, and (3) the after-care phase. This paper argues that the time available in many ER projects in developing countries using international funding is very often insufficient, and discusses the reasons for some of the most important bottlenecks: (1) time realistically required to produce thorough baseline data and obtain historic site information that are indispensable to develop a robust remediation design, (2) lack of an adequate legal and regulatory framework, overlapping and/or conflicting provisions of national standards and discrepancies with international best practice, (3) unmanaged stakeholder expectations regarding the actual health and environmental risks, justification and prioritisation of remedial actions, and the achievable remediation end state. Insufficient resources for after-care, monitoring and, if required, corrective action is another major issue that, in the experience of the authors, jeopardises the sustainability of remediation success. Consequently by applying the lessons learnt from previous ER projects in developing (and developed) countries and taking them on board during the programming phase of new ER projects, international funding agencies could greatly help to avoid these obstacles. (authors)

12 MANAGEMENT OF RADIOACTIVE AND NON-RADIOACTIVE W↗