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At least 865 records · Page 48

Analysis of in Vitro Evolution Reveals the Underlying Distribution of Catalytic Activity Among Random Sequences

The emergence of catalytic RNA is believed to have been a key event during the origin of life. Understanding how catalytic activity is distributed across random sequences is fundamental to estimating the probability that catalytic sequences would emerge. Here, we analyze the in vitro evolution of triphosphorylating ribozymes and translate their fitnesses into absolute estimates of catalytic activity for hundreds of ribozyme families. The analysis efficiently identified highly active ribozymes and estimated catalytic activity with good accuracy. The evolutionary dynamics follow Fisher’s Fundamental Theorem of Natural Selection and a corollary, permitting retrospective inference of the distribution of fitness and activity in the random sequence pool for the first time. The frequency distribution of rate constants appears to be log-normal, with a surprisingly steep dropoff at higher activity, consistent with a mechanism for the emergence of activity as the product of many independent contributions.

Abe Pressman↗

High-bandwidth reconfigurable data acquisition card

A reconfigurable data acquisition card including at least one field programmable gate array (FPGA) and a configurable bus switch coupled with the FPGA. The bus switch forms at least first and second ports used by the FPGA, the bus switch being adaptable for insertion into a connection having a number of lanes at least equal to a combined number of lanes in the first and second ports. The data acquisition card further includes multiple optical transmitters and optical receivers. Each optical transmitter and optical receiver is coupled with a corresponding transceiver in the FPGA via at least one optical fiber having multiple communication links. Timing circuitry in the data acquisition card is coupled with clock generation and distribution circuitry in the FPGA and is configured to distribute clock and timing signals to detector front-ends with fixed latency and to synchronize input/output links with a system clock generated by the FPGA.

Chen, Kai↗

Adaptive Management of Computing and Network Resources for Spacecraft Systems

It is likely that NASA's future spacecraft systems will consist of distributed processes which will handle dynamically varying workloads in response to perceived scientific events, the spacecraft environment, spacecraft anomalies and user commands. Since all situations and possible uses of sensors cannot be anticipated during pre-deployment phases, an approach for dynamically adapting the allocation of distributed computational and communication resources is needed. To address this, we are evolving the DeSiDeRaTa adaptive resource management approach to enable reconfigurable ground and space information systems. The DeSiDeRaTa approach embodies a set of middleware mechanisms for adapting resource allocations, and a framework for reasoning about the real-time performance of distributed application systems. The framework and middleware will be extended to accommodate (1) the dynamic aspects of intra-constellation network topologies, and (2) the complete real-time path from the instrument to the user. We are developing a ground-based testbed that will enable NASA to perform early evaluation of adaptive resource management techniques without the expense of first deploying them in space. The benefits of the proposed effort are numerous, including the ability to use sensors in new ways not anticipated at design time; the production of information technology that ties the sensor web together; the accommodation of greater numbers of missions with fewer resources; and the opportunity to leverage the DeSiDeRaTa project's expertise, infrastructure and models for adaptive resource management for distributed real-time systems.

Pfarr, Barbara↗

Real-Time Drag Optimization of Aspect Ratio 13.5 Common Research Model with Distributed Flap System

This paper presents a real-time drag optimization study of the aspect ratio 13.5 Common Research Model (CRM) with a distributed mini-plain flap system. A surrogate aerodynamic model of the aspect ratio 13.5 CRM is developed based on an aerodynamic database computed by a transonic panel method to capture the aerodynamic coefficients as functions of the angle of attack, flap deflections, and Mach number. A recursive least-squares parameter estimation algorithm is designed to estimate the aerodynamic parameters of the surrogate model. The estimated surrogate model is then used in an on-line drag optimization strategy based on an adjoint method. The results of the real-time drag optimization indicate a drag reduction of 2.46% for Mach 0.80, 3.37% for Mach 0.85, and 1.95% for Mach 0.88. The results show the convergence of all parameter estimates.

Drag Optimization↗

Real-time simulator and controller of power system using distributed data streaming server

Systems and methods for simulating and controlling a power system in real time, using a controller, are provided. The controller includes a simulation layer to simulate an operation of the power system, a disturbance generation layer to provide data to the simulation layer to disturb the simulated operation of the power system, an application layer to display the simulated operation of the power system and generate a control signal to control, based on the simulated operation of the power system, at least one element of the power system, and a distributed data streaming server (D2S2) to allow interoperability among the simulation layer, the disturbance layer, and the application layer.

Li, Fangxing↗

Tempus Project (Final Report)

This final technical report tracks the accomplishments of the Tempus Project to the statement of project objectives and resulting deliverables. The objective of the Tempus project was to develop and demonstrate the capabilities of a secure, modular, and customizable time synchronization platform that provides layers of protection from GPS spoofing attacks and other vulnerabilities. These vulnerabilities present a challenge to power system operators utilizing GPS-based time synchronization, as time synchronization increasingly plays a critical role in the efficient and reliable operation of power systems. The Tempus project addressed these concerns through the development of a secure, customizable time synchronization platform. The Tempus platform applies a layered approach to time security that protects from manipulation of timing systems used by power utilities. The Tempus platform consists of a component framework utilizing modularized time sources and customizable manipulation detection algorithms. With multiple time sources, and comparisons between sources and tracking sudden or subtle changes to the timing phase and time information, the Tempus system can detect and mitigate compromised timing sources.

24 POWER TRANSMISSION AND DISTRIBUTION↗

Assessment of Crew Time for Maintenance and Repair Activities for Lunar Surface Missions

NASA is currently evaluating different methods to predict how much time crewmembers will spend conducting repair and maintenance activities on future space missions. As mission scope and spacecraft architectures change, understanding how crew repair and maintenance timelines are impacted by mission operations and technology changes is vital for future mission planning. Past work has been done using historical International Space Station (ISS) data to accurately predict crew habitation and operation timelines, resulting in the development of NASA’s Exploration Crew Time Model (ECTM). However, understanding crew maintenance and repair requirements has posed a unique challenge due to the complexity of available datasets, the probabilistic nature of sub-system failures, and the impacts of reliability growth on failure rates. This paper presents a methodology to collect and condition empirical repair and maintenance time data from available datasets, to extrapolate from that data to estimate projected maintenance and repair times for a lunar Surface Habitat (SH), and to assess how uncertainty in repair time could impact utilization time on the lunar surface. NASA ISS maintenance and crew time data are logged into two central databases: the Maintenance Data Collection (MDC) and the Operations Planning Timeline Integration System (OPTimIS). Separately, each of these two datasets capture only portions of the complete set of data required to generate an accurate assessment of crew time spent on maintenance activities at a sub-system level. To create a more useful crew time estimate for maintenance timelines, the authors developed a methodology to capture relevant data from each set and combine and utilize that data by linking crew time requirements to specific components. The authors compare the failure logs in the MDC to crew activity logs pulled from OPTimIS and then process the data to estimate required repair time for each failure and repair event. The entire maintenance activity dataset is then categorized based on the class of failed component to ensure a significant sample size for each class and accurate crew time estimates for any components lacking relevant data. This resultant component repair time data can be used in the future to generate Mean Time to Repair (MTTR) estimates and confidence intervals for each class of component based on a probabilistic distribution of documented maintenance events. These improved MTTR values can then be applied to candidate element sub-system architectures, along with component Mean Time Between Failure (MTBF) data to generate distributions for potential required system crew repair time estimates for a given mission. The authors applied these modeling methods to a case study of a crewed mission to the planned SH and produced expected corrective maintenance crew time distributions. The results produced an expected corrective maintenance crew time at over 24 hours per mission, and a maintenance crew time distribution that reflects the importance of planning for sufficient maintenance requirements each mission. Repair time distributions can then be used to develop more accurate crew schedules and to assess potential available utilization time.

Crew Time↗

Spaceborne Processor Array

A Spaceborne Processor Array in Multifunctional Structure (SPAMS) can lower the total mass of the electronic and structural overhead of spacecraft, resulting in reduced launch costs, while increasing the science return through dynamic onboard computing. SPAMS integrates the multifunctional structure (MFS) and the Gilgamesh Memory, Intelligence, and Network Device (MIND) multi-core in-memory computer architecture into a single-system super-architecture. This transforms every inch of a spacecraft into a sharable, interconnected, smart computing element to increase computing performance while simultaneously reducing mass. The MIND in-memory architecture provides a foundation for high-performance, low-power, and fault-tolerant computing. The MIND chip has an internal structure that includes memory, processing, and communication functionality. The Gilgamesh is a scalable system comprising multiple MIND chips interconnected to operate as a single, tightly coupled, parallel computer. The array of MIND components shares a global, virtual name space for program variables and tasks that are allocated at run time to the distributed physical memory and processing resources. Individual processor- memory nodes can be activated or powered down at run time to provide active power management and to configure around faults. A SPAMS system is comprised of a distributed Gilgamesh array built into MFS, interfaces into instrument and communication subsystems, a mass storage interface, and a radiation-hardened flight computer.

Chow, Edward T.↗

Distribution Function Instead of Steady-State Assumption in Time-Series Simulation

The quasi-steady-state assumption in time-series simulation is inadequate to model phenomena of interest to energy system integration such as inverter clipping, sell-back of excess electricity to a utility and utility hosting capacity, and battery throughput. Researchers are working on stochastic modeling, higher-resolution time series data, and machine learning approaches to address this need. This poster describes a distribution function that allows a maximum value, minimum value, and shape to the curve that can vary within each time-step based only on data inputs at the resolution of that time step (eg. Hourly). The distribution function is not used to synthesize high-resolution data, rather scalar integrals are used to calculate the quantities of interest within each time step. The form of the distribution function shows significant reduction in error when compared to 1 minute data and commercial software employing the distribution function (HOMER Pro version 14.3 and higher) shows a much improved estimate of inverter clipping in an example.

battery↗

Expected Utility Distributions for Flexible, Contingent Execution

This paper presents a method for using expected utility distributions in the execution of flexible, contingent plans. A utility distribution maps the possible start times of an action to the expected utility of the plan suffix starting with that action. The contingent plan encodes a tree of possible courses of action and includes flexible temporal constraints and resource constraints. When execution reaches a branch point, the eligible option with the highest expected utility at that point in time is selected. The utility distributions make this selection sensitive to the runtime context, yet still efficient. Our approach uses predictions of action duration uncertainty as well as expectations of resource usage and availability to determine when an action can execute and with what probability. Execution windows and probabilities inevitably change as execution proceeds, but such changes do not invalidate the cached utility distributions, thus, dynamic updating of utility information is minimized.

Bresina, John L.↗

Detecting Seasonal Ice Dynamics in Satellite Images

Fully understanding how glaciers respond to environmental change will require new methods to help us identify the onset of ice acceleration events and observe how dynamic signals propagate within glaciers. In particular, observations of ice dynamics on seasonal timescales may offer insights into how a glacier interacts with various forcing mechanisms throughout the year. The task of generating continuous ice velocity time series that resolve seasonal variability is made more difficult by a spotty satellite record that contains no optical observations throughout the dark, polar winters. Furthermore, velocities obtained by feature tracking are marked by high noise when image pairs are separated by short time intervals and contain no direct insights into variability that occurs between images separated by long time intervals. In this paper, we describe a method of analyzing optical or SAR-derived feature-tracked velocities to characterize the magnitude and timing of seasonal ice dynamic variability. Our method is agnostic to data gaps and is able to recover climatological average winter velocities regardless of the availability of direct observations during winter. Using characteristic image acquisition times and error distributions from Antarctic image pairs in the ITS_LIVE dataset, we generate synthetic ice velocity time series, then apply our method to recover imposed magnitudes of seasonal variability within ±1.4 m yr−1. We then validate the techniques by comparing our results to GPS data collected on Russell Glacier in Greenland. The methods presented here may be applied to better understand how ice dynamic signals propagate on seasonal timescales, and what mechanisms control the flow of the world’s ice.

Chad A. Greene↗

Comparison of the solar cosmic ray events on May 7, 1978, and November 22, 1977

Neutron monitor data from the IMP 7 and 8 satellites are used in the present analysis of the cosmic ray events of Nov. 22, 1977, and May 7, 1978, in order to determine the energy spectra of the solar protons from 50 MeV to 10 GeV, together with pitch angle distributions, intensity-time profiles, and anisotropy-time profiles. The solar proton energy spectra obtained agree with the overlapping energy range when the pitch angle distribution is taken into account, and it is noted that the energy spectra covering three decades of energy and eight of intensity, together with their time variations, were very similar for the two events. The May 1978 event is important for the study of solar particle acceleration and their subsequent injection into the interplanetary medium. Although the solar proton propagation of the November 1977 event was diffusive, the solar particle injection was also time-extended and energy-dependent.

Debrunner, H.↗

Distribution of genetic variation underlying adult migration timing in steelhead of the Columbia River basin

Abstract Fish migrations are energetically costly, especially when moving between freshwater and saltwater, but are a viable strategy for Pacific salmon and trout ( Oncorhynchus spp.) due to the advantageous resources available at various life stages. Anadromous steelhead ( O. mykiss ) migrate vast distances and exhibit variation for adult migration phenotypes that have a genetic basis at candidate genes known as greb1L and rock1 . We examined the distribution of genetic variation at 13 candidate markers spanning greb1L , intergenic, and rock1 regions versus 226 neutral markers for 113 populations ( n = 9,471) of steelhead from inland and coastal lineages in the Columbia River. Patterns of population structure with neutral markers reflected genetic similarity by geographic region as demonstrated in previous studies, but candidate markers clustered populations by genetic variation associated with adult migration timing. Mature alleles for late migration had the highest frequency overall in steelhead populations throughout the Columbia River, with only 9 of 113 populations that had a higher frequency of premature alleles for early migration. While a single haplotype block was evident for the coastal lineage, we identified multiple haplotype blocks for the inland lineage. The inland lineage had one haplotype block that corresponded to candidate markers within the greb1L gene and immediately upstream in the intergenic region, and the second block only contained candidate markers from the intergenic region. Haplotype frequencies had similar patterns of geographic distribution as single markers, but there were distinct differences in frequency between the two haplotype blocks for the inland lineage. This may represent multiple recombination events that differed between lineages where phenotypic differences exist between freshwater entry versus arrival timing as indicated by Micheletti et al. (2018a). Redundancy analyses were used to model environmental effects on allelic frequencies of candidate markers, and significant variables were migration distance, temperature, isothermality, and annual precipitation. This study improves our understanding of the spatial distribution of genetic variation underlying adult migration timing in steelhead as well as associated environmental factors and has direct conservation and management implications.

Collins, Erin E.↗

Dispersion of ensembles of non-interacting particles

The dynamics of an ensemble of noninteracting particles dispersing from a common origin and moving in a common force field with an initial distribution of momenta is analyzed using an approach where the particles are considered as a continuum described by a phase-space distribution function. General solutions are obtained for both the distribution function and the associated spatial density function. The linear case of small departures from circular orbits in an axisymmetric gravitational field is treated along with the specific case of particle dispersion from an object in a circular orbit in the same type of field. Numerical results are presented for the latter case, and consideration is given to the inverse problem of determining the initial time and velocity distribution from knowledge of the ensemble structure at a later time. Explicit results are provided for the case of an ellipsoidal distribution of initial momenta, and a numerical procedure is indicated for treating more general cases.

Heard, W. B.↗

Evidence of Multiple Reconnection Lines at the Magnetopause from Cusp Observations

Recent global hybrid simulations investigated the formation of flux transfer events (FTEs) and their convection and interaction with the cusp. Based on these simulations, we have analyzed several Polar cusp crossings in the Northern Hemisphere to search for the signature of such FTEs in the energy distribution of downward precipitating ions: precipitating ion beams at different energies parallel to the ambient magnetic field and overlapping in time. Overlapping ion distributions in the cusp are usually attributed to a combination of variable ion acceleration during the magnetopause crossing together with the time-of-flight effect from the entry point to the observing satellite. Most "step up" ion cusp structures (steps in the ion energy dispersions) only overlap for the populations with large pitch angles and not for the parallel streaming populations. Such cusp structures are the signatures predicted by the pulsed reconnection model, where the reconnection rate at the magnetopause decreased to zero, physically separating convecting flux tubes and their parallel streaming ions. However, several Polar cusp events discussed in this study also show an energy overlap for parallel-streaming precipitating ions. This condition might be caused by reopening an already reconnected field line, forming a magnetic island (flux rope) at the magnetopause similar to that reported in global MHD and Hybrid simulations

flux transfer events↗

A Robust Parallel Distributed State Estimation for Large Scale Distribution Systems

The growing need and interest in real-time monitoring of large distribution networks motivated by the rapid population of renewable sources, EVs and etc. demand a computationally efficient state estimation framework. Furthermore, this paper presents an improved computational framework for implementing a robust state estimator using a multi-core processor. The main contribution of the paper is the proposed computational framework along with two partitioning strategies which enable fast and robust state estimation for large scale radial and/or meshed distribution systems. Formulation of the proposed method and its implementation are described in detail. Performance of the estimator is tested by simulations first using a small 84-bus radial distribution system. Then the method’s scalability is demonstrated by simulations on two very large scale distribution networks one configured radially and the other meshed each containing over 12,500 buses.

42 ENGINEERING↗

Optimal regulation in systems with stochastic time sampling

An optimal control theory that accounts for stochastic variable time sampling in a distributed microprocessor based flight control system is presented. The theory is developed by using a linear process model for the airplane dynamics and the information distribution process is modeled as a variable time increment process where, at the time that information is supplied to the control effectors, the control effectors know the time of the next information update only in a stochastic sense. An optimal control problem is formulated and solved for the control law that minimizes the expected value of a quadratic cost function. The optimal cost obtained with a variable time increment Markov information update process where the control effectors know only the past information update intervals and the Markov transition mechanism is almost identical to that obtained with a known and uniform information update interval.

Montgomery, R. C.↗