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At least 865 records · Page 48

Airspace Research and Development Portfolio Assessment of Urban Air Mobility using Knowledge Graph Data Science

National Aeronautics and Space Administration (NASA) is spearheading an innovative digital engineering approach to integrate, communicate, and facilitate the research of Urban Air Mobility (UAM) operations. The UAM vision is one in which advanced technologies and new operational procedures enable practical and cost-effective air transport as an integrated mode of movement of people and goods throughout metropolitan areas. To safely support UAM operations at scale in the National Airspace System (NAS), NASA’s Air Traffic Management-Exploration (ATM-X) project has been conducting research that evolves the UAM air traffic management system towards a highly automated and operationally flexible system of the future. The complexity of UAM airspace evolution to accommodate the increasing tempo of UAM operations over time is managed through the UAM airspace research roadmap, which is a system engineering approach to the R&D of complex system-of-systems, where system’s interdependencies make it nearly impossible to define requirements for individual elements of the system in isolation. These interdependencies form a knowledge graph (node-link network) with a highly complex structure far beyond the human user’s ability to extract insights for project management’s research portfolio assessment. This study applies advanced data analytics in knowledge graph to the UAM knowledge graph to facilitate the portfolio assessment.

ATM↗

Airspace Research and Development Portfolio Assessment of Urban Air Mobility using Knowledge Graph Data Science

National Aeronautics and Space Administration (NASA) is spearheading an innovative digital engineering approach to integrate, communicate, and facilitate the research of Urban Air Mobility (UAM) operations. The UAM vision is one in which advanced technologies and new operational procedures enable practical and cost-effective air transport as an integrated mode of movement of people and goods throughout metropolitan areas. To safely support UAM operations at scale in the National Airspace System (NAS), NASA’s Air Traffic Management-Exploration (ATM-X) project has been conducting research that evolves the UAM air traffic management system towards a highly automated and operationally flexible system of the future. The complexity of UAM airspace evolution to accommodate the increasing tempo of UAM operations over time is managed through the UAM airspace research roadmap, which is a system engineering approach to the R&D of complex system-of-systems, where system’s interdependencies make it nearly impossible to define requirements for individual elements of the system in isolation. These interdependencies form a knowledge graph (node-link network) with a highly complex structure far beyond the human user’s ability to extract insights for project management’s research portfolio assessment. This study applies advanced data analytics in knowledge graph to the UAM knowledge graph to facilitate the portfolio assessment.

ATM↗

Integrated Computational Materials Engineering (ICME) Capability Maturity Levels for Ecosystems Enabling Digital Transformation

Digital engineering (DE) and integrated computational materials engineering (ICME) are widely recognized as critical enablers of faster, more affordable, and more reliable aerospace systems. However, many organizations have struggled to realize the promised return on investment (ROI) from digital initiatives. A primary reason is the absence of a shared, decision-focused framework that distinguishes simple digitization of existing workflows from true digital transformation that fundamentally changes how engineering decisions are made. This paper introduces an ICME capability maturity framework that fills this gap. The framework defines six cumulative ICME capability maturity levels (CMLs), explicitly tied to decision authority, engineering integration, optimization, and uncertainty management across material, process, structure, and performance scales. It is designed to complement established readiness metrics such as technology readiness levels (TRLs), manufacturing readiness levels (MRLs), and integration readiness levels (IRLs), by addressing a missing dimension: the conditions required for model-informed decision authority across scales. A unifying figure and capability table illustrate the six-level ICME Capability Maturity Framework, showing how organizations progress from digitization—with limited or negative ROI—to true digital transformation, where ICME-enabled workflows deliver measurable improvements in decision quality, cycle time, risk reduction, and reuse. The framework is intended for both technical practitioners and executive leadership, providing a common language to assess current state, guide roadmaps, align software ecosystem investments, and set realistic expectations for digital transformation outcomes. A regulatory-relevant statement clarifying the relationship between ICME capability and existing certification frameworks is provided.

ICME↗

Near-Single-Cell Proteomics Profiling of the Proximal Tubular and Glomerulus of the Normal Human Kidney

Molecular assessments at the single-cell level can accelerate biological research by providing detailed assessments of cellular organization and tissue heterogeneity in both disease and health. The human kidney has complex multi-cellular states with varying functionality, much of which can now be completely harnessed with recent technological advances in tissue proteomics at a near single-cell level. We discuss the foundational steps in the first application of this mass spectrometry (MS) based proteomics method for analysis of sub-sections of the normal human kidney, as part of the Kidney Precision Medicine Project (KPMP). Using approximately 30-40 laser captured micro-dissected kidney cells, we identified more than 2500 human proteins, with specificity to the proximal tubular (PT; n=25 proteins) and glomerular (Glom; n=67 proteins) regions of the kidney and their unique metabolic functions. This pilot study provides the roadmap for application of our near-single-cell proteomics workflow for the analysis of other renal micro-compartments, on a larger scale, to unravel perturbations of renal sub-cellular function in the normal kidney as well as different etiologies of acute and chronic kidney disease.

60 APPLIED LIFE SCIENCES↗

The X-Ray Surveyor Mission Concept Study: Forging the Path to NASA Astrophysics 2020 Decadal Survey Prioritization

The X-Ray Surveyor mission concept is unique among those being studied for prioritization in the NASA Astrophysics 2020 Decadal Survey. The X-Ray Surveyor mission will explore the high-energy Universe; providing essential and complimentary observations to the Astronomy Community. The NASA Astrophysics Roadmap (Enduring Quests, Daring Visions) describes the need for an X-Ray Observatory that is capable of addressing topics such as the origin and growth of the first supermassive black holes, galaxy evolution and growth of the cosmic structure, and the origin and evolution of the stars that make up our Universe. To address these scientifically compelling topics and more, an Observatory that exhibits leaps in capability over that of previous X-Ray Observatories in needed. This paper describes the current status of the X-Ray Surveyor Mission Concept Study and the path forward, which includes scientific investigations, technology development, and community participation.

X-Ray Surveyor↗

Thermodynamic Constraints on Electromicrobial Protein Production

Global consumption of protein is projected to double by the middle of the 21st century. However, protein production is one of the most energy intensive and environmentally damaging parts of the food supply system today. Electromicrobial production technologies that combine renewable electricity and CO 2 -fixing microbial metabolism could dramatically increase the energy efficiency of commodity chemical production. Here we present a molecular-scale model that sets an upper limit on the performance of any organism performing electromicrobial protein production. We show that engineered microbes that fix CO 2 and N 2 using reducing equivalents produced by H 2 -oxidation or extracellular electron uptake could produce amino acids with energy inputs as low as 64 MJ kg −1 , approximately one order of magnitude higher than any previous estimate of the efficiency of electromicrobial protein production. This work provides a roadmap for development of engineered microbes that could significantly expand access to proteins produced with a low environmental footprint.

60 APPLIED LIFE SCIENCES↗

Human Space Exploration: The Moon, Mars, and Beyond

America is returning to the Moon in preparation for the first human footprint on Mars, guided by the U.S. Vision for Space Exploration. This presentation will discuss NASA's mission, the reasons for returning to the Moon and going to Mars, and how NASA will accomplish that mission in ways that promote leadership in space and economic expansion on the new frontier. The primary goals of the Vision for Space Exploration are to finish the International Space Station, retire the Space Shuttle, and build the new spacecraft needed, to return people to the Moon and go to Mars. The Vision commits NASA and the nation to an agenda of exploration that also includes robotic exploration and technology development, while building on lessons learned over 50 years of hard-won experience. Why the Moon? Many questions about the Moon's potential resources and how its history is linked to that of Earth were spurred by the brief Apollo explorations of the 1960s and 1970s. This new venture will carry more explorers to more diverse landing sites with more capable tools and equipment for extended expeditions. The Moon also will serve as a training ground before embarking on the longer, more difficult trip to Mars. NASA plans to build a lunar outpost at one of the lunar poles, learn to live off the land, and reduce dePendence on Earth for longer missions. America needs to extend its ability to survive in hostile environments close to our home planet before astronauts will reach Mars, a planet very much like Earth. NASA has worked with scientists to define lunar exploration goals and is addressing the opportunities for a range of scientific study on Mars. In order to reach the Moon and Mars within a lifetime and within budget, NASA is building on common hardware, shared knowledge, and unique experience derived from the Apollo Saturn, Space Shuttle and contemporary commercial launch vehicle programs. The journeys to the Moon and Mars will require a variety of vehicles, including the Ares I Crew Launch Vehicle, which transports the Orion Crew Exploration Vehicle, and the Ares V Cargo Launch Vehicle, which transports the Lunar Surface Access Module. The architecture for the lunar missions will use one launch to ferry the crew into orbit, where it will rendezvous with the Lunar Module in the Earth Departure Stage, which will then propel the combination into lunar orbit. The imperative to explore space with the combination of astronauts and robots will be the impetus for inventions such as solar power and water and waste recycling. This next chapter in NASA's history promises to write the next chapter in American history, as well. It will require this nation to provide the talent to develop tools, machines, materials, processes, technologies, and capabilities that can benefit nearly all aspects of life on Earth. Roles and responsibilities are shared between a nationwide Government and industry team. The Exploration Launch Projects Office at the Marshall Space Flight Center manages the design, development, testing, and evaluation of both vehicles and serves as lead systems integrator. A little over a year after it was chartered, the Exploration Launch Projects team is testing engine components, refining vehicle designs, performing wind tunnel tests, and building hardware for the first flight test of Ares I-l, scheduled for spring 2009. The U.S. Vision for Space Exploration lays out a roadmap for a long-term venture of discovery. This endeavor will inspire and attract the best and brightest students to power this nation successfully to the Moon, Mars, and beyond. If one equates the value proposition for space with simple dollars and cents, the potential of the new space economy is tremendous, from orbital space delivery services for the International Space Station to mining and solar energy collection on the Moon and asteroids. The Vision for Space Exploration is fundamentally about bringing the resources of the solar system within the economic sphere of humaind. Given the immense size of our solar system, the amount of available material and energy within it present an enormous economic opportunity.

Sexton, Jeffrey D.↗

Pathway to Zero Energy Windows: Advancing Technologies and Market Adoption

As of 2021, buildings account for 39.1% of total U.S. primary energy use and 75% of total U.S. electricity use. Much of this energy is used to maintain a comfortable indoor environment. The building envelope consists of transparent and opaque elements that serve as a controllable barrier to help maintain the indoor environment regardless of external conditions. The envelope also allows the exchange of light and air, as well as other transfers with the external environment when it is beneficial for the building occupants. By leveraging desirable external environmental conditions (e.g., fresh air and natural light) and mitigating the influence of undesirable conditions (e.g., moisture, hot or cold temperatures, wind), the building envelope can reduce the need for space conditioning and electric light, and thus reduce energy use associated with lighting and heating, cooling, and ventilation equipment. In turn, high-performance building envelopes can reduce the substantial CO 2 emissions associated with energy use to satisfy heating, cooling, and lighting needs in buildings. The U.S. Department of Energy (DOE) Building Technologies Office's (BTO's) Emerging Technologies program supports R&D for technologies, systems, and software tools that can contribute to reductions in building energy use. Emerging Technologies funding is distributed competitively through solicitations (e.g., Funding Opportunity Announcements and National Lab Calls, which in general are open to applications from industry, academia, national laboratories, and other entities) and other mechanisms. This document focuses on R&D for windows and window system technologies and will provide guidance for BTO's investments in developing the next generation of high-performance, affordable, cost competitive windows, as well as integrated daylighting and shading technologies in partnership with industry and researchers. This document also addresses areas where DOE invests in software and design tools that translate sophisticated and complex physics into easy-to-use energy performance and optimization methods used by industry and other stakeholders for implementation.

32 ENERGY CONSERVATION, CONSUMPTION, AND UTILIZATI↗

Resources, Training, and Education Under the Heliostat Consortium: Industry Gap Analysis and Building a Resource Database

Concentrating solar power is not a widely deployed or known technology area, and the heliostat workforce community in the United States is currently small, with knowledge and expertise not widely available. The resource, training, and education (RTE) topic within the Heliostat Consortium (HelioCon) was established to address this. RTE encompasses resources, practices, and programs to ensure that (1) newcomers to the heliostat development community have an adequate knowledge base and training to conduct R&D efforts, (2) outsiders to the field are provided with resources and opportunities to join the workforce, and (3) the workforce community is a productive, healthy, and fulfilling environment for all workers. In the first year of the project, a roadmap study was conducted, in which the major gaps in RTE were identified by consulting experts in the industry, with the top gap being the lack of public accessibility to concentrating solar-thermal power (CSP) knowledge. Here, to address this, the HelioCon team has been developing a centralized web-based resource database, containing a reference library, educational videos, lists of components suppliers and software/metrology tools, a power tower plant database, and information on existing standards/guidelines.

14 SOLAR ENERGY↗

Crystalline Disposal R&D at LBNL: FY20 Progress Report

Within the Spent Fuel & Waste Science and Technology (SFWST) Program, research work continues further with the goal to better understand long-term performance of disposal systems in three main geologic rock types: clay/shale, salt, and crystalline rock. This report documents LBNL’s research activities related to investigations of crystalline host rock according to the scope of two work packages: SF-20LB01030207 “Crystalline International Collaborations – LBNL,” and SF-20LB01030203 “Crystalline Disposal R&D – LBNL.” These research activities correspond are related to key Features, Events, and Processes (FEPs), ranked in importance from medium to high, as listed in Table 7 of the Used Fuel Disposition Campaign Disposal Research and Development Roadmap (FCR&D-USED-2011-000065 REV0) (Nutt, 2011). Specifically, these research activities address FEP 2.2.01, Excavation Disturbed Zone (EZD). The results of these research activities provide important insights into understanding and predicting flow and transport processes that could occur in low-permeability crystalline rocks, in which fractures might serve as main conduits for fluid flow and radionuclide transport. The evolution of the EDZ during the excavation of the tunnel as well as the evolution of microcrack growth within the EDZ after the emplacement of backfill are critical for predicting the long- term behavior of the EDZ. A number of factors including stress, temperature, water activity, capillary pressure, chemistry, and mineralogy can affect the rock evolution, which require advanced experimental tools to study it.

11 NUCLEAR FUEL CYCLE AND FUEL MATERIALS↗

Mitigating Extreme Environments for In-Situ Jupiter and Venus Missions

In response to the recommendations by the National Research Council (NRC), NASA's Solar System Exploration (SSE) Roadmap identified the in situ exploration of Venus and Jupiter as high priority science objectives. For Jupiter, deep entry probes are recommended, which would descend to approx.250 km - measured from the 1 bar pressure depth. At this level the pressure would correspond to approx.100 bar and the temperature would reach approx.500(deg)C. Similarly, at the surface of Venus the temperature and pressure conditions are approx.460(deg)C and approx.90 bar. Lifetime of the Jupiter probes during descent can be measured in hours, while in{situ operations at and near the surface of Venus are envisioned over weeks or months. In this paper we discuss technologies, which share commonalities in mitigating these extreme conditions over proposed mission lifetimes, specially focusing on pressure and temperature environments.

Venus↗

NASA's Space Launch System: A New Capability for Science and Exploration

NASA's Marshall Space Flight Center (MSFC) is directing efforts to build the Space Launch System (SLS), a heavy-lift rocket that will launch the Orion Multi-Purpose Crew Vehicle (MPCV) and other high-priority payloads into deep space. Its evolvable architecture will allow NASA to begin with human missions beyond the Moon and then go on to transport astronauts or robots to distant places such as asteroids and Mars. Developed with the goals of safety, affordability, and sustainability in mind, SLS will start with 10 percent more thrust than the Saturn V rocket that launched astronauts to the Moon 40 years ago. From there it will evolve into the most powerful launch vehicle ever flown, via an upgrade approach that will provide building blocks for future space exploration. This paper will explain how NASA will execute this development within flat budgetary guidelines by using existing engines assets and heritage technology, from the initial 70 metric ton (t) lift capability through a block upgrade approach to an evolved 130-t capability, and will detail the progress that has already been made toward a first launch in 2017. This paper will also explore the requirements needed for human missions to deep-space destinations and for game-changing robotic science missions, and the capability of SLS to meet those requirements and enable those missions, along with the evolution strategy that will increase that capability. The International Space Exploration Coordination Group, representing 12 of the world's space agencies, has worked together to create the Global Exploration Roadmap, which outlines paths towards a human landing on Mars, beginning with capability-demonstrating missions to the Moon or an asteroid. The Roadmap and corresponding NASA research outline the requirements for reference missions for all three destinations. The SLS will offer a robust way to transport international crews and the air, water, food, and equipment they would need for extended trips to asteroids, the Moon, and Mars. SLS also offers substantial capability to support robotic science missions, offering benefits such as improved mass margins and radiation mitigation, and reduced mission durations. The SLS rocket, using significantly higher C3 energies, can more quickly and effectively take the mission directly to its destination, reducing trip time and cost. As this paper will explain, the SLS is making measurable progress toward becoming a global infrastructure asset for robotic and human scouts of all nations by providing the robust space launch capability to deliver sustainable solutions for advanced exploration.

Robinson, Kimberly F.↗

NASA's Space Launch System: A New Capability for Science and Exploration

The National Aeronautics and Space Administration's (NASA's) Marshall Space Flight Center (MSFC) is directing efforts to build the Space Launch System (SLS), a heavy-lift rocket that will launch the Orion Multi-Purpose Crew Vehicle (MPCV) and other high-priority payloads into deep space. Its evolvable architecture will allow NASA to begin with human missions beyond the Moon and then go on to transport astronauts or robots to distant places such as asteroids and Mars. Developed with the goals of safety, affordability, and sustainability in mind, SLS will start with 10 percent more thrust than the Saturn V rocket that launched astronauts to the Moon 40 years ago. From there it will evolve into the most powerful launch vehicle ever flown, via an upgrade approach that will provide building blocks for future space exploration. This paper will explain how NASA will execute this development within flat budgetary guidelines by using existing engines assets and heritage technology, from the initial 70 metric ton (t) lift capability through a block upgrade approach to an evolved 130-t capability, and will detail the progress that has already been made toward a first launch in 2017. This paper will also explore the requirements needed for human missions to deep-space destinations and for game-changing robotic science missions, and the capability of SLS to meet those requirements and enable those missions, along with the evolution strategy that will increase that capability. The International Space Exploration Coordination Group, representing 12 of the world's space agencies, has worked together to create the Global Exploration Roadmap, which outlines paths towards a human landing on Mars, beginning with capability-demonstrating missions to the Moon or an asteroid. The Roadmap and corresponding NASA research outline the requirements for reference missions for all three destinations. The SLS will offer a robust way to transport international crews and the air, water, food, and equipment they would need for extended trips to asteroids, the Moon, and Mars. SLS also offers substantial capability to support robotic science missions, offering benefits such as improved mass margins and radiation mitigation, and reduced mission durations. The SLS rocket, using significantly higher characteristic energy (C3), can more quickly and effectively take the mission directly to its destination, reducing trip time and cost. As this paper will explain, the SLS is making measurable progress toward becoming a global infrastructure asset for robotic and human scouts of all nations by providing the robust space launch capability to deliver sustainable solutions for advanced exploration.

Crumbly, Christopher M.↗

The Research Plan: Closing the ExMC Med02 "Pharmacy" Gap

HRP Human Research Roadmap: Risk and Gap Risk of Adverse Health Outcomes and Decrements in Performance due to Inflight Medical Conditions. Med02 "Pharmacy" Gap: We do not have the capability to provide a safe and effective medication formulary for exploration missions delivering a recommendation for a chemically stable, safe, and effective medication formulary that will support the operational needs of exploration space missions research strategy evidence-based formulary and models innovative analytical tools and methodologies novel treatments and preventive measures Planned review by a panel of experts from the pharmaceutical industry, regulatory, and academic scientific communities Formulary Selection Formulary Potency and Shelf life Formulary Safety and Toxicity Novel Technology Proof-of-Concept Portable real-time chemical analysis Innovative drug development / design

Daniels, Vernie↗

Unlocking Mesoscopic Disorder in Graphitic Carbon with Spectroelectrochemistry

Intrinsic structural and oxidic defects activate graphitic carbon electrodes towards electrochemical reactions underpinning energy conversion and storage technologies. Yet, these defects can also disrupt the long-range and periodic arrangement of carbon atoms, thus, the characterization of graphitic carbon electrodes necessitates in-situ atomistic differentiation of graphitic regions from mesoscopic bulk disorder. Here, we leverage the combined techniques of in-situ attenuated total reflectance infrared spectroscopy and first-principles calculations to reveal that graphitic carbon electrodes exhibit electric-field dependent infrared activity that is sensitive to the bulk mesoscopic intrinsic disorder. With this platform, we identify graphitic regions from amorphous domains by discovering that they demonstrate opposing electric-field-dependent infrared activity under electrochemical conditions. Our work provides a roadmap for identifying mesoscopic disorder in bulk carbon materials under potential bias.

Disordered graphitic carbon electrodes↗

Towards Sustainable Post-Exascale Leadership Computing

As computing systems approach the limits of traditional silicon technology, the diminishing returns in performance per watt present a significant barrier to sustaining growth in HPC. From a large-scale scientific supercomputing facility point of view, we propose a multifaceted strategy toward specialized hardware and architectures that are optimized for energy efficiency in specific applications. We also emphasize the need for integrating energy-aware practices across all levels of HPC, from system design and software development to operational policies. We discuss strategic opportunities such as the adoption of application-specific accelerators, the development of energy-efficient algorithms, and the implementation of data-driven operational analytics. Our goal is to develop a comprehensive roadmap ensuring that future leadership systems at OLCF can meet scientific demands while operating within stringent energy budgets, thereby supporting sustainable computing growth.

Shin, Woong↗

Tracing NASA Contributions Toward Aviation Safety Stakeholder Guidance

The System-Wide Safety project at NASA is developing the concept and a subset of supporting technologies for evolving safety management from a post-accident iterative improvement on safety performed by large commercial operators only to predictive and increasingly autonomous safety functions that are performed during operations across vehicles, airports, and services. The system of interest is the In-time Aviation Safety Management System (IASMS), recommended by the National Academies for NASA to develop the concept in coordination with the broad and diverse community of stakeholders in aviation safety. Because the system context is the airspace and aviation industry, it is important to create and maintain traceability from the research work and system architecture elements developed at NASA to community-created roadmaps and aviation agency guidance.

IASMS↗

Energize the Future - Systems Engineering Processes and Methods: Tracing NASA Contributions Toward Aviation Safety Stakeholder Guidance

The System-Wide Safety project at NASA is developing the concept and a subset of supporting technologies for evolving safety management from a post-accident iterative improvement on safety performed by large commercial operators only to predictive and increasingly autonomous safety functions that are performed during operations across vehicles, airports, and services. The system of interest is the In-time Aviation Safety Management System (IASMS), recommended by the National Academies for NASA to develop the concept in coordination with the broad and diverse community of stakeholders in aviation safety. Because the system context is the airspace and aviation industry, it is important to create and maintain traceability from the research work and system architecture elements developed at NASA to community-created roadmaps and aviation agency guidance.

MBSE↗