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At least 865 records · Page 48

Open Science for Life in Space: Data Sharing and Tools for Knowledge Discovery

The next era in human space exploration is rapidly approaching. The use of health countermeasures and biomonitoring systems for space missions are required to counteract space health hazards and to support life to thrive in deep space (e.g., humans, animals, plants, crops; entire ecosystems within spacecrafts/habitats/spacesuits). The development of these mission components will be highly dependent on our understanding of basic biological and health responses to myriad space hazards (ionizing radiation, altered gravitational fields, altered day-night cycles, confined isolation, hostile-closed environments, distance-duration from Earth, planetary dust-regolith, and extreme temperatures/atmospheres). The fast-growing array of space biological and mission telemetry data, which in the past was simply archived after minimal analysis, holds great potential once applied to these mission challenges if it can be reorganized and formatted for Open Science. Organizing the data for such analysis is a challenge because of its multi-hierarchical, multi-modal, and heterogenous nature (molecular, cellular, tissue, organ, whole organism, behavior, ecosystem, microbiome; tabular, omics, imaging, video, biospecimen, environmental physical-chemical telemetry). This session focuses on current approaches in this domain such as: making space biological data FAIR (findable, accessible, interoperable, reusable), effective data ingestion/dissemination, observational versus experimental data, Open Science collaborations, data analysis techniques, AI/ML/knowledge graph/modeling methods, and data integration/discovery tools.

open science↗

How representative are FLUXNET measurements of surface fluxes during temperature extremes?

In response to a warming climate, temperature extremes are changing in many regions of the world. Therefore, understanding how the fluxes of sensible heat, latent heat and net ecosystem exchange respond and contribute to these changes is important. We examined 216 sites from the open access Tier 1 FLUXNET2015 and free fair-use La Thuile data sets, focussing only on observed (non-gap-filled) data periods. We examined the availability of sensible heat, latent heat and net ecosystem exchange observations coincident in time with measured temperature for all temperatures, and separately for the upper and lower tail of the temperature distribution, and expressed this availability as a measurement ratio. We showed that the measurement ratios for both sensible and latent heat fluxes are generally lower (0.79 and 0.73 respectively) than for temperature measurements, and the measurement ratio of net ecosystem exchange measurements are appreciably lower (0.42). However, sites do exist with a high proportion of measured sensible and latent heat fluxes, mostly over the United States, Europe and Australia. Few sites have a high proportion of measured fluxes at the lower tail of the temperature distribution over very cold regions (e.g. Alaska, Russia) or at the upper tail in many warm regions (e.g. Central America and the majority of the Mediterranean region), and many of the world's coldest and hottest regions are not represented in the freely available FLUXNET data at all (e.g. India, the Gulf States, Greenland and Antarctica). However, some sites do provide measured fluxes at extreme temperatures, suggesting an opportunity for the FLUXNET community to share strategies to increase measurement availability at the tails of the temperature distribution. We also highlight a wide discrepancy between the measurement ratios across FLUXNET sites that is not related to the actual temperature or rainfall regimes at the site, which we cannot explain. Our analysis provides guidance to help select eddy covariance sites for researchers interested in understanding and/or modelling responses to temperature extremes.

54 ENVIRONMENTAL SCIENCES↗

Adipose-derived stromal cells inhibit prostate cancer cell proliferation inducing apoptosis

Highlights: • AdSC transplantation exhibits inhibitory effect on tumor progressions of PCa cells. • AdSC-induced PCa cell apoptosis may occur via the TGF-β signaling pathway. • High expression of the TGF-β1 gene in AdSCs. - Abstract: Mesenchymal stem cells (MSCs) have generated a great deal of interest in the field of regenerative medicine. Adipose-derived stromal cells (AdSCs) are known to exhibit extensive proliferation potential and can undergo multilineage differentiation, sharing similar characteristics to bone marrow-derived MSCs. However, as the effect of AdSCs on tumor growth has not been studied sufficiently, we assessed the degree to which AdSCs affect the proliferation of prostate cancer (PCa) cell. Human AdSCs exerted an inhibitory effect on the proliferation of androgen-responsive (LNCaP) and androgen-nonresponsive (PC3) human PCa cells, while normal human dermal fibroblasts (NHDFs) did not, and in fact promoted PCa cell proliferation to a degree. Moreover, AdSCs induced apoptosis of LNCaP cells and PC3 cells, activating the caspase3/7 signaling pathway. cDNA microarray analysis suggested that AdSC-induced apoptosis in both LNCaP and PC3 cells was related to the TGF-β signaling pathway. Consistent with our in vitro observations, local transplantation of AdSCs delayed the growth of tumors derived from both LNCaP- and PC3-xenografts in immunodeficient mice. This is the first preclinical study to have directly demonstrated that AdSC-induced PCa cell apoptosis may occur via the TGF-β signaling pathway, irrespective of androgen-responsiveness. Since autologous AdSCs can be easily isolated from adipose tissue without any ethical concerns, we suggest that therapy with these cells could be a novel approach for patients with PCa.

60 APPLIED LIFE SCIENCES↗

Kinetic, Thermodynamic, and Structural Insight into the Mechanism of Phosphopantetheine Adenylyltransferase from Mycobacterium tuberculosis

Phosphopantetheine adenylyltransferase (PPAT) catalyzes the penultimate step in the coenzyme A (CoA) biosynthetic pathway, reversibly transferring an adenylyl group from ATP to 4'-phosphopantetheine (PhP) to form dephosphocoenzyme A. This reaction sits at the branch point between the de novo pathway and the salvage pathway, and has been shown to be a rate-limiting step in the biosynthesis of CoA. Importantly, bacterial and mammalian PPATs share little sequence homology, making the enzyme a potential target for antibiotic development. A series of steady-state kinetic, product inhibition, and direct binding studies with Mycobacterium tuberculosis PPAT (MtPPAT) was conducted and suggests that the enzyme utilizes a nonrapid-equilibrium random bi-bi mechanism. The kinetic response of MtPPAT to the binding of ATP was observed to be sigmoidal under fixed PhP concentrations, but substrate inhibition was observed at high PhP concentrations under subsaturating ATP concentrations, suggesting a preferred pathway to ternary complex formation. Negative cooperativity in the kinetic response of MtPPAT to PhP binding was observed under certain conditions and confirmed thermodynamically by isothermal titration calorimetry, suggesting the formation of an asymmetric quaternary structure during sequential ligation of substrates. Asymmetry in binding was also observed in isothermal titration calorimetry experiments with dephosphocoenzyme A and CoA. X-ray structures of MtPPAT in complex with PhP and the nonhydrolyzable ATP analogue adenosine-5'-[({alpha},{beta})-methyleno]triphosphate were solved to 1.57 {angstrom} and 2.68 {angstrom}, respectively. These crystal structures reveal small conformational changes in enzyme structure upon ligand binding, which may play a role in the nonrapid-equilibrium mechanism. We suggest that the proposed kinetic mechanism and asymmetric character in MtPPAT ligand binding may provide a means of reaction and pathway regulation in addition to that of the previously determined CoA feedback.

60 APPLIED LIFE SCIENCES↗

Accelerated Assessment of Critical Infrastructure in Aiding Recovery Efforts During Natural and Human-made Disaster

Relief and recovery from disasters (both natural and human-made) require a coordinated approach across several federal and state government agencies. In order to achieve optimal resource allocation and deployment of first responders, accurate and timely assessment of the impact and extent of destruction are the cornerstones to any recovery effort. Ideally, this knowledge should be gathered and shared within the first 0-24 hours (termed as "Acute Phase" by the U.S. CDC guideline) for informed decision-making. But achieving this poses significant challenges for the data collection and data harmonization processes, particularly when voluminous data are being generated from diverse and distributed sources during the disaster responses. To this end, this work developed a scalable and efficient workflow to dynamically collect and harmonize crowd-sourced geographic multi-modal data, and then assess critical infrastructure (CI) damaged during disaster events. We demonstrate the application of our framework with two real-world experiences in addressing post-disaster recovery efforts - for the Bahamas (Natural - due to Hurricane Dorian, 2019) and Beirut (Human-made - due to explosion caused by the ammonium nitrate stored in a warehouse, 2020). We have illustrated that a coordinated effort is needed for planning as well as for execution to achieve informed decision making.

Thakur, Gautam Malviya↗

Differential Regulation of Maize and Sorghum Orthologs in Response to the Fungal Pathogen Exserohilum turcicum

Pathogens that infect more than one host offer an opportunity to study how resistance mechanisms have evolved across different species. Exserohilum turcicum infects both maize and sorghum and the isolates are host-specific, offering a unique system to examine both compatible and incompatible interactions. We conducted transcriptional analysis of maize and sorghum in response to maize-specific and sorghum-specific E. turcicum isolates and identified functionally related co-expressed modules. Maize had a more robust transcriptional response than sorghum. E. turcicum responsive genes were enriched in core orthologs in both crops, but only up to 16% of core orthologs showed conserved expression patterns. Most changes in gene expression for the core orthologs, including hub genes, were lineage specific, suggesting a role for regulatory divergent evolution. We identified several defense-related shared differentially expressed (DE) orthologs with conserved expression patterns between the two crops, suggesting a role for parallel evolution of those genes in both crops. Many of the differentially expressed genes (DEGs) during the incompatible interaction were related to quantitative disease resistance (QDR). This work offers insights into how different hosts with relatively recent divergence interact with a common pathogen. Our results are important for developing resistance to this critical pathogen and understanding the evolution of host-pathogen interactions.

54 ENVIRONMENTAL SCIENCES↗

Planetary-scale circulations in the presence of climatological and wave-induced heating

Interaction between the large-scale circulation and the convective pattern is investigated in a coupled system governed by the linearized primitive equations. Convection is represented in terms of two components of heating: A 'climatological component' is prescribed stochastically to represent convection that is maintained by fixed distributions of land and sea and sea surface temperature (SST). An 'induced component' is defined in terms of the column-integrated moisture flux convergence to represent convection that is produced through feedback with the circulation. Each component describes the envelope organizing mesoscale convective activity. As SST on the equator is increased, induced heating amplifies in the gravest zonal wavenumbers at eastward frequencies, where positive feedback offsets dissipation. Under barotropic stratification, a critical SST of 29.5 C results in positive feedback exactly cancelling dissipation in wavenumber 1 for an eastward phase speed of 6 m/s. Sympathetic interaction between the circulation and the induced heating is the basis for 'frictional wave-Conditional Instability of the Second Kind (CISK)', which is distinguished from classical wave-CISK by rendering the gravest zonal dimensions most unstable. Under baroclinic stratification, the coupled system exhibits similar behavior. The critical SST is only 26.5 C for conditions representative of equinox, but in excess of 30 C for conditions representative of solstice. Having the form of an unsteady Walker circulation, the disturbance produced by frictional wave-CISK compares favorably with the observed life cycle of the Madden-Julian oscillation (MJO). SST above the critical value produces an amplifying disturbance in which enhanced convection coincides with upper-tropospheric westerlies and is positively correlated with temperature and surface convergence. Conversely, SST below the critical value produces a decaying disturbance in which enhanced convection coincides with upper-tropospheric easterlies and is nearly in quadrature with temperature and surface convergence. While sharing essential features with the MJO in the Eastern Hemisphere, frictional wave-CISK does not explain observed behavior in the Western Hemisphere, where the convective signal is largely absent. Comprised of Kelvin structure with the same frequency, observed behavior in the Western Hemisphere can be understood as a propagating response that is excited in and radiates away from the fluctuation of convection in the Eastern Hemisphere.

Salby, Murry L↗

The arabidopsis thaliana AGRAVITROPIC 1 gene encodes a component of the polar-auxin-transport efflux carrier

Auxins are plant hormones that mediate many aspects of plant growth and development. In higher plants, auxins are polarly transported from sites of synthesis in the shoot apex to their sites of action in the basal regions of shoots and in roots. Polar auxin transport is an important aspect of auxin functions and is mediated by cellular influx and efflux carriers. Little is known about the molecular identity of its regulatory component, the efflux carrier [Estelle, M. (1996) Current Biol. 6, 1589-1591]. Here we show that mutations in the Arabidopsis thaliana AGRAVITROPIC 1 (AGR1) gene involved in root gravitropism confer increased root-growth sensitivity to auxin and decreased sensitivity to ethylene and an auxin transport inhibitor, and cause retention of exogenously added auxin in root tip cells. We used positional cloning to show that AGR1 encodes a putative transmembrane protein whose amino acid sequence shares homologies with bacterial transporters. When expressed in Saccharomyces cerevisiae, AGR1 promotes an increased efflux of radiolabeled IAA from the cells and confers increased resistance to fluoro-IAA, a toxic IAA-derived compound. AGR1 transcripts were localized to the root distal elongation zone, a region undergoing a curvature response upon gravistimulation. We have identified several AGR1-related genes in Arabidopsis, suggesting a global role of this gene family in the control of auxin-regulated growth and developmental processes.

Non-NASA Center↗

STEReO: Combining NASA Technologies and Partnerships to Transform Current-Day Emergency Response Operations

STEReO brings together several technologies in Unmanned Aircraft Systems (UAS) Traffic Management (UTM), Autonomy, Communications, Human Factors, and Domain Expertise & Tools, aimed at providing scalability and flexibility, as well as operational resiliency to dynamic changes during a disaster event. Some of the concepts STEReO explores are: collaborative tools to ingest remote sensing information and distribute a common mission operating picture, apply ad-hoc communication networks to facilitate timely information sharing and communication of changes, vehicle-to-vehicle and onboard autonomy technologies ensure the safety and resiliency of operations, and apply NASA?s UAS traffic management system (UTM) as a public safety UAS Service Supplier (USS) to access and coordinate use of the airspace by both manned and unmanned operations. The potential benefits of STEReO include: standardized, cross-platform communication means increased interoperability and ease of cooperation/collaboration, increased situation awareness and common operating picture allow for earlier detection and decision making, and scalable to size and complexity of environment, operations, and mission objectives. This presentation gives an informational overview of the STEReO project to attendees of the annual North American Aerial Fire Fighting conference (AFFNA 2020).

Mercer, Joey S.↗

Stereo: Combining NASA Technologies and Partnerships to Transform Current-Day Emergency Response Operations

STEReO brings together several technologies in Unmanned Aircraft Systems (UAS) Traffic Management (UTM), Autonomy, Communications, Human Factors, and Domain Expertise & Tools, aimed at providing scalability and flexibility, as well as operational resiliency to dynamic changes during a disaster event. Some of the concepts STEReO explores are: collaborative tools to ingest remote sensing information and distribute a common mission operating picture, apply ad-hoc communication networks to facilitate timely information sharing and communication of changes, vehicle-to-vehicle and onboard autonomy technologies ensure the safety and resiliency of operations, and apply NASA's UAS traffic management system (UTM) as a public safety UAS Service Supplier (USS) to access and coordinate use of the airspace by both manned and unmanned operations. The potential benefits of STEReO include: standardized, cross-platform communication means increased interoperability and ease of cooperation/collaboration, increased situation awareness and common operating picture allow for earlier detection and decision making, and scalable to size and complexity of environment, operations, and mission objectives. This presentation gives an informational overview of the STEReO project to the members of the US Forest Service (USFS) region 5 aerial supervisor steering committee (ASSC).

Mercer, Joey↗

Structure of the C-terminal domain of Saccharomyces cerevisiae Nup133, a component of the nuclear pore complex

Nuclear pore complexes (NPCs), responsible for the nucleo-cytoplasmic exchange of proteins and nucleic acids, are dynamic macromolecular assemblies forming an eight-fold symmetric co-axial ring structure. Yeast (Saccharomyces cerevisiae) NPCs are made up of at least 456 polypeptide chains of {approx}30 distinct sequences. Many of these components (nucleoporins, Nups) share similar structural motifs and form stable subcomplexes. We have determined a high-resolution crystal structure of the C-terminal domain of yeast Nup133 (ScNup133), a component of the heptameric Nup84 subcomplex. Expression tests yielded ScNup133(944-1157) that produced crystals diffracting to 1.9{angstrom} resolution. ScNup133(944-1157) adopts essentially an all {alpha}-helical fold, with a short two stranded {beta}-sheet at the C-terminus. The 11 {alpha}-helices of ScNup133(944-1157) form a compact fold. In contrast, the previously determined structure of human Nup133(934-1156) bound to a fragment of human Nup107 has its constituent {alpha}-helices are arranged in two globular blocks. These differences may reflect structural divergence among homologous nucleoporins.

59 BASIC BIOLOGICAL SCIENCES↗

Spatiotemporal control of mitochondrial network dynamics in astroglial cells

Highlights: • Astrocytes display highly complex mitochondrial architectures in vivo. • Mitochondrial trafficking and dynamics in astrocytes are regulated. • Mitochondria critically contribute to astrocyte Ca{sup 2+} handling. • Astrocyte reacting to injury undergo marked changes in mitochondrial dynamics. Mitochondria are increasingly recognized for playing important roles in regulating the evolving metabolic state of mammalian cells. This is particularly true for nerve cells, as dysregulation of mitochondrial dynamics is invariably associated with a number of neuropathies. Accumulating evidence now reveals that changes in mitochondrial dynamics and structure may play equally important roles also in the cell biology of astroglial cells. Astroglial cells display significant heterogeneity in their morphology and specialized functions across different brain regions, however besides fundamental differences they seem to share a surprisingly complex meshwork of mitochondria, which is highly suggestive of tightly regulated mechanisms that contribute to maintain this unique architecture. Here, we summarize recent work performed in astrocytes in situ indicating that this may indeed be the case, with astrocytic mitochondrial networks shown to experience rapid dynamic changes in response to defined external cues. Although the mechanisms underlying this degree of mitochondrial re-shaping are far from being understood, recent data suggest that they may contribute to demarcate astrocyte territories undergoing key signalling and metabolic functions.

60 APPLIED LIFE SCIENCES↗

Community-Based Transactive Coordination Mechanism for Enabling Grid Edge Systems

The changing landscape of the electricity industry, characterized by a surge in distributed energy resources (DERs) and proactive customers, necessitates practical solutions for coordinated operations especially at the distribution-level. This paper introduces a community-based transactive coordination mechanism designed to incentivize customers for providing localized and system-level services reflected through real-time prices. The work presents a bidding approach for communities with DERs, such as solar photovoltaic (PV) and battery energy storage systems (BESS), to formulate their price-responsiveness for retail energy coordination, emphasizing a community-centric model. By sending bidding curves to a third-party, the mechanism enables customers with DER assets to actively participate in localized coordination with the load serving entity (LSE), thereby supplementing each other’s and even the utilities needs through a shared energy economy. The proposed transactive mechanism is implemented leveraging a co-simulation framework that integrates a distribution grid simulator and Python-based agents for performance evaluation. Collaboration with a local utility to access real distribution feeder models and consumption profiles yields simulation results demonstrating the potential to reduce costs by 12\% for communities with DERs like PV and BESS.

Community-based coordination, grid-edge systems, R↗

Dataset 2: A National Dataset on Human Choices in Pooled Rideshare, 2022

Dataset 2: A National Dataset on Human Choices in Pooled Rideshare, 2022. Dataset Description: Pooled Rideshare Acceptance Survey - Phase 2 (2022, N = 2,884). This dataset captures responses from a nationally representative sample of 2,884 adults across the United States to understand choice behaviors between personal and pooled rideshare services. The primary objective of this research is to investigate choice behaviors in rideshare services and provide insights that inform service design, policymaking, and transportation planning, with the aim of encouraging pooled rideshare adoption and enhancing transportation network energy efficiency. Data was collected via an online survey administered through a national panel provider. Participants ranged in age from 18 to 94 years, and representation from all U.S. regions. The survey was designed with a focus on investigating the stated-preference between personal and pooled rideshare services. Each participant responded to 20 stated-preference questions, where they were presented with a hypothesized situation to choose between a personal rideshare option and a pooled rideshare option to complete a trip. The sociodemographic information and attitudes towards factors of pooled rideshare acceptance were also collected to support the comprehensive investigation of participants’ rideshare choice behaviors. - Phase_2_Final - Each row represents an individual respondent, and each column corresponds to a variable such as stated-preference scenario attributes, stated-preference scenario responses, attitudes toward specific service features, and sociodemographic data. The data is available in both .CSV and .SAV formats. - Phase_2_Final_MapFile - The accompanying data dictionary explains all variable labels, response scales, and codes. An .XLSX format of the full survey instrument is included to support interpretation and reuse of the dataset.

32 ENERGY CONSERVATION, CONSUMPTION, AND UTILIZATI↗

Managing Climate-Driven Zoonotic Risk Interagency Workshop Report

In July 2022, Sandia National Laboratories hosted a workshop in Washington, D.C., bringing together representatives from eleven Federal Government agencies, responsible for public health, environmental security, and biodefense, as well as six Department of Energy (DOE) National Laboratories, to discuss how to work together to address climate-driven zoonotic disease risk. The primary goal of this workshop was to provide a forum for Federal and DOE National Lab attendees to share their missions, programs, and capabilities relevant to zoonotic disease emergence, to discuss how to best leverage these collective resources, identify key gaps, and to determine an effective path forward.

54 ENVIRONMENTAL SCIENCES↗

Oakland University Cybersecurity Center (Final Scientific/Technical Report)

This report summarizes the outcomes of Award DE-CR0000023, “Oakland University Cybersecurity Center,” a 31-month project funded by the U.S. Department of Energy Office of Cybersecurity, Energy Security, and Emergency Response (CESER). The project addressed cybersecurity risks facing small and medium-sized manufacturers (SMMs) transitioning to Industry 4.0. The project integrated customer discovery, applied research, and cybersecurity training development. A total of 51 cybersecurity assessments identified significant gaps in baseline practices, incident response, and workforce capability. Research efforts produced a scalable mitigation framework tailored to SMM environments, and workforce analysis identified persistent talent gaps. Eight cybersecurity training modules were developed and deployed via Oakland University’s Professional and Continuing Education (PACE) platform. All objectives were completed, with 98.93% federal budget utilization and cost share exceeding requirements. The project establishes a scalable model for strengthening cybersecurity resilience and workforce capacity across U.S. manufacturing supply chains.

24 POWER TRANSMISSION AND DISTRIBUTION↗

APEX-CAMBIUM: A Case Study in Advantages and Challenges of International Cooperation for the International Space Station

It is generally agreed that space science benefits from an international collaboration. There are different mechanisms to make this happen but to recognize opportunities requires a keen awareness of the activities, people and respective strengths. Apex- Cambium is a joint Canadian Space Agency (CSA)-National Aeronautics and Space Administration (NASA) initiative. It was made possible in large part through the good relations and shared willingness to meet a common objective, that of doing exciting science in space. The actual mechanics of bringing an international project together can be divided into two perspectives: programmatic and implementation. The programmatic component includes recognizing complementarities, bringing science together, and the need to have Agencies approve and accept joint responsibility for the mission. The implementation component involves working to define science requirements, available resources and assigning individual responsibilities while keeping the overall success criteria as a collective objective. The APEX-CAMB11.JM mission will be described from the point of view of both CSA and NASA. Suggestions on how to facilitate these types of initiatives will be provided and highlights of the APEX-Cambium collaboration will be provided.

Cox, David↗

Molecular Inventory and Comparative Organic Profiling of A Homogenized Aggregate Sample From Asteroid (101955) Bennu

Evaluating the distribution and diversity of solvent-soluble organic molecules in extraterrestrial materials provide information about the physicochemical environments where prebiotic chemistry occurred and is essential for assessing the inventory of prebiotic compounds available to the early Earth. In this work, we conducted a comprehensive molecular characterization of solvent-soluble organic compounds in a homogenized aggregate sample (ID: OREX-800107-128) of unsorted regolith from asteroid (101955) Bennu returned by NASA’s OSIRIS-REx mission. Using two-dimensional gas chromatography coupled with high-resolution time-of-flight mass spectrometry (GC×GC-HRMS), we identified 87 organic compounds across several molecular classes, including alkanes, polycyclic aromatic hydrocarbons, and nitrogen-, oxygen-, and sulfur-bearing species. Comparison with the organic inventory of CI (Orgueil), C2-ungrouped (Tagish Lake and Tarda), and CM2 (Murchison) carbonaceous chondrites revealed that Bennu sample OREX-800107-128 is most similar to Tagish Lake and Tarda yet compositionally distinct from all of these meteorites. This Bennu sample exhibits a relatively high abundance of low-molecular-weight aromatics (e.g., toluene), pyridine derivatives, and sulfur species such as dimethyl sulfite, consistent with episodic low-temperature aqueous alteration. The presence of these organic compounds suggests that this material experienced chemically diverse processes in the parent body conducive to complex organic synthesis, including aldol condensation reactions responsible for N- and O-bearing compounds. We also compared the molecular distributions of this Bennu sample and previously analyzed samples from (162173) Ryugu to assess potential common origins between these two carbonaceous asteroids. Bennu shows more chemically diverse and nitrogen-rich organic materials than Ryugu. While both asteroids share broadly similar primitive compositions, the observed chemical differences indicate distinct evolutionary histories within a likely common formation environment though whether Bennu and Ryugu derive from a single compositionally heterogeneous parent body or from multiple closely related progenitors remains unresolved. Further detailed comparative analyses of material from Bennu, Ryugu, and specific carbonaceous meteorites (e.g., Tagish Lake and Tarda) will provide new insights into how the N-rich molecular profile observed in Bennu samples was formed and evolved in the outer Solar System.

sample return↗