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At least 865 records · Page 48

Automating the Study of Microbial Adaptation Dynamics on and off the ISS

The International Space Station (ISS) not only serves as a unique environment for humans, but also the microorganisms that join alongside. Many microbes present on the spacecraft arrive via humans, and as they interact with different surfaces they begin to inhabit those locations. Much like how human health has shown to be impacted by these extreme environments, microbial viability and response to stress also changes. Experimental evolution (EE) can aid in studying how microbes’ growth and activity changes within the ISS environments by applying controlled stressors to microbial cultures and monitoring their response over generations. EE studies are commonly done manually in laboratories, but, with multiple environmental variables to measure and adjust, it becomes highly labor-intensive, prone to human error, and challenging to scale. A multipurpose automated EE system named the AADEC has been developed to address these problems. This system integrates multiple sensors into a single fluidic chamber using UV-C flux, temperature, and media composition as stressors. AADEC contains five sensors: oxidation-reduction potential, electrical conductivity, pH, dissolved oxygen, and optical density. On their own, each is able to provide certain information on growth rate or metabolism; together, they show in detail how stressors affect life. AADEC studies can be conducted on Earth and repeated aboard the ISS to see how behavior changes when exposed to space mission stressors such as microgravity and radiation. AADEC’s auxiliary systems include peristaltic pumps for media exchange, magnetic rods for agitation, and a Raspberry Pi microprocessor to monitor, store, and adjust stressor levels real-time. This allows researchers to gather information within rapid generations, data and accuracy which is challenging to achieve through manual studies. With further miniaturization and automation, such as a more robust single-piece fluidics card, AADEC has the potential to be developed as a spacecraft payload. Support: NASA Ames CIF Award

Automating↗

Mercury Lander: Transformative Science from the Surface of the Innermost Planet

As an end-member of terrestrial planet formation, Mercury holds unique clues about the original distribution of elements in the earliest stages of solar system development and how planets and exoplanets form and evolve in close proximity to their host stars. This Mercury Lander mission concept enables in situ surface measurements that address several fundamental science questions raised by MESSENGER’s pioneering exploration of Mercury. Such measurements are needed to understand Mercury’s unique mineralogy and geochemistry; to characterize the proportionally massive core’s structure; to measure the planet’s active and ancient magnetic fields at the surface; to investigate the processes that alter the surface and produce the exosphere; and to provide ground truth for current and future remote datasets. NASA’s Planetary Mission Concept Studies (PMCS) program awarded this study to a multidisciplinary team led by Dr. Carolyn Ernst of the Johns Hopkins Applied Physics Laboratory (APL), to evaluate the feasibility of accomplishing transformative science through a New-Frontiers-class, landed mission to Mercury in the next decade. The resulting mission concept achieves one full Mercury year (~88 Earth days) of surface operations with an ambitious, high-heritage, landed science payload, corresponding well with the New Frontiers mission framework.

Mercury lander↗

Overview of a NASA Centennial Challenges Prize Competition to Address Crew Nutritional Needs for Long-Duration Space Exploration Missions

Historically, competitions and prizes such as those executed by the National Aeronautics and Space Administration (NASA) Centennial Challenges (CC) program have created broader avenues through which to spur innovation from unlikely sources. In 2005, Congress amended the National Aeronautics and Space Act of 1958 to authorize NASA to create challenges through which prizes could be awarded to United States citizens or entities that succeeded in meeting challenge objectives. Over the past 15 years, the CC program has initiated more than 20 challenges in a variety of technology areas, including: propulsion, robotics, communications and navigation, human health, science instrumentation, nanotech, materials/structures and aerodynamics. This paper provides the background, status and ongoing plans by NASA’s CC program in developing a Deep Space Food Challenge (formerly the Lunar Nutrition Challenge) as one approach to fulfilling Space Policy Directive 1 (To the Moon, then Mars”).

Centennial Challenges↗

Extreme Environments Solar Power Project For Use Near Jupiter

The Extreme Environment Solar Power (EESP) Project goal was to develop solar cell and solar array design concept technologies for space power applications in high radiation and low solar intensity, low temperature (LILT) environments. NASA missions focused on outer planets, such as Jupiter, are subjected to intense radiation while experiencing less than ten percent of the solar flux relative to a mission in the general vicinity of Earth. Under these conditions, present solar array technology is not as efficient in converting the sun’s energy, and the solar array performance degrades quickly due to the additional radiation exposure. The EESP Project objectives were accomplished through four competitively selected contracts. These contracts were awarded with a Base and two option periods of performance. The Base requirements included System Design and Component Test & Analysis with a duration of nine and one half (9.5) months. The Option I requirements involved the fabrication of test hardware that NASA would evaluate following its delivery, and this period of performance had a duration of thirteen (13) months. The Option II requirements involved the fabrication of a scalable system prototype that can be integrated into a system level application and be demonstrated in a relevant environment. Option II had a duration of fifteen (15) months. The Transformational Array (TA) is an array concept developed by JHU-APL with Deployable Space Systems (DSS), SolAero Technologies and NewForge Technologies that proceeded through all three contract periods. The TA combines the DSS Roll Out Solar Array (ROSA) with Flexible Array Concentrator Technology (FACT) and SolAero’s Inverted Metamorphic Multijunction (IMM) solar cells for operation in the EESP Project environment. To achieve the EESP Project goals, the JHU-APL team conducted several investigations to improve performance of the solar cells and increase their efficiency, reduce outgassing contamination of the concentrators from the solar cell assembly adhesives, and to test the robustness of a sample blanket during deployment and retraction. Additionally, the team performed vibration, thermal cycling, and performance tests at a Standard Power Module (SPM) level. At the end of Option II, the JHU-APL team achieved the following performance metrics: • 39% beginning of life (BOL) cell efficiency at 5 AU and -125 C • 29% end of life (EOL) efficiency at the blanket level at 50 W/m2, -125 C and 4x1015 1 MeV e/cm2 • Increased specific power to 8 W/kg at EOL for the entire array including structure, deployment, and pointing mechanisms • Demonstrated the ability to survive numerous deploy-retract cycles without degradation • Reached a current System-Level Technology Readiness Level, TRL5 This presentation will describe the Transformational Array and component technologies and will discuss future potential uses for the system.

Anna Maria Pal↗

NO2 Anomalies - Economy Attribution and Rapid Climate Response

Using principal component (PC) analysis of 16 years of monthly series of NO2 from OMI/Aura, we show that it is the third PC (PC3) from the full hierarchy of principal modes that is best coupled with the economic indicators. This coupling is positive, i.e. PC3 and economic indicators manifest positive covariance. However, the economic variability can explain only 40% of the information in PC3. Furthermore, this mode by itself explains only 3% of the total deseasonalized NO2 variability. We thus conclude that, while having an unambiguous impact, the economy can be awarded at best third order of importance in driving the deseasonalized NO2 series, i.e. after seasonal variability is removed from the series. Once we identified PC3 as the NO2 mode that is coupled with economic variability, we use this mode as an indicator and look for rapid climate adjustments to that part of NO2 variability that we are confident is coupled with the economic variability. We focus on observational data from the Atmospheric Infrared Sounder (AIRS) on board of NASA Aqua satellite, decompose series of surface skin temperature and clear-sky outgoing longwave radiances (OLR) into principal components, and identify potential impacts of NO2 PC3 on these climate variables.

NO2↗

NO2 Anomalies - Economy Attribution and Rapid Climate Response

Using principal component (PC) analysis of 16 years of monthly series of NO2 from OMI/Aura, we show that it is the third PC (PC3) from the full hierarchy of principal modes that is best coupled with the economic indicators. This coupling is positive, i.e. PC3 and economic indicators manifest positive covariance. However, the economic variability can explain only 40%of the information in PC3. Furthermore, this mode by itself explains only 3% of the total deseasonalized NO2 variability. We thus conclude that, while having an unambiguous impact, the economy can be awarded at best third order of importance in driving the deseasonalized NO2 series, i.e. after seasonal variability is removed from the series. Once we identified PC3 as the NO2 mode that is coupled with economic variability, we use this mode as an indicator and look for rapid climate adjustments to that part of NO2 variability that we are confident is coupled with the economic variability. We focus on observational data from the Atmospheric Infrared Sounder (AIRS) on board of NASA Aqua satellite, decompose series of surface skin temperature and clear-sky outgoing longwave radiances (OLR) into principal components, and identify potential impacts of NO2 PC3 on these climate variables.

NO2↗

A Decade of NASA Strategic Astrophysics Technology Investments: Technology Maturation, Infusion, and Other Benefits

NASA’s Astrophysics Division (APD) funds development of cutting-edge technology to enable its missions to achieve ambitious and groundbreaking science goals. These technology development efforts are managed by the Physics of the Cosmos (PCOS), Cosmic Origins (COR), and Exoplanet Exploration (ExE) Programs. The NASA Strategic Astrophysics Technology (SAT) Program was established in 2009 as a new technology maturation program to fill the gap in the Technology Readiness Level (TRL) range from 3 to 6. Since program inception, 100 SAT grants have been openly competed and awarded, along with dozens of direct-funded projects, leading to a host of technologies advancing their TRLs and/or being infused into space and suborbital missions and ground-based projects. We present the portfolio distribution in terms of specific technology areas addressed, including optics, detectors, coatings, coronagraphs, starshades, lasers, electronics, cooling systems, and micro-thruster subsystems. We show an analysis of the rate of TRL advances, infusion success stories, and other benefits such as training the future astrophysics workforce, including students and postdoctoral fellows hired by projects. Finally, we present APD’s current strategic technology maturation priorities for investment, enabling a range of future strategic astrophysics missions

NASA, astrophysics, technology development, optics↗

Runtime Verification - 17 Years Later

Runtime verification is the discipline of analyzing program executions using rigorous methods. The discipline covers such topics as specification-based monitoring, where single executions are checked against formal specifications; predictive runtime analysis, where properties about a system are predicted/inferred from single (good) executions; specification mining from execution traces; visualization of execution traces; and to be fully general: computation of any interesting information from execution traces. Finally, runtime verification also includes fault protection, where monitors actively protect a running system against errors. The paper is written as a response to the ‘Test of Time Award’ attributed to the authors for their 2001 paper [45]. The present paper provides a brief overview of what lead to that paper, what has happened since, and some perspectives on the future of the field.

Rosu, Grigore↗

Design and Development of the CubeSat Infrared Atmospheric Sounder (CIRAS

The CubeSat Infrared Atmospheric Sounder (CIRAS) is a NASA Earth Science Technology Office (ESTO) sponsored mission to demonstrate key technologies used in very high spectral resolution infrared remote sensing of Earth’s atmosphere from space. CIRAS was awarded under the ESTO In-flight Validation of Earth Science Technologies (InVEST) program in 2015 and is currently under development at NASA JPL with key subsystems being developed by industry. CIRAS incorporates key new instrument technologies including a 2D array of High Operating Temperature Barrier Infrared Detector (HOT-BIRD) material, selected for its high uniformity, low cost, low noise and higher operating temperatures than traditional materials. The second key technology is an MWIR Grating Spectrometer (MGS) designed to provide imaging spectroscopy for atmospheric sounding in a CubeSat volume. The MGS is under development by Ball Aerospace with the grating and slit developed by JPL. The third key technology is an infrared blackbody fabricated with JPL’s black silicon to have very high emissivity in a flat plate construction. JPL will also develop the mechanical, electronic and thermal subsystems for CIRAS, while the spacecraft will be a 6U CubeSat developed by Blue Canyon Technologies. This paper provides an overview of the design and acquisition approach, and provides a status of the current development.

Vengel, Tony↗

Cryocooler Electronics Enable Thermal Imaging of Planetary Objects in Deep Space

Iris Technology Corporation received NASA SBIR awards to advance its cryocooler electronics, which control mechanical cryocoolers that enable thermal imaging systems to capture data to improve our knowledge of water and possibly life in space. Originally partnering with the Air Force SBIR program, Iris has since won several contracts to provide its cryocooler electronics on NASA missions — including a mission to examine the surface of Jupiter’s moon Europa — and on a satellite mission with the Air Force.

Mark H Davidson↗

Development of Electrolytic Oxygen Recovery System for Advanced Life Support

The oxygen (O2) recovery system for the International Space Station (ISS) can recover approximately 50 percent of O2 from metabolic carbon dioxide (CO2). Increasing the O2 recovery rate and closing the open loop for future long duration crewed missions in space beyond Low Earth Orbit (LEO) is essential. There are several developmental efforts underway to increase the recovery rate. However, most of these technologies result in a complex, heavy, and power consuming system. The desired exploration O2 recovery system would be reliable and efficient with maximum O2 recovery. Marshall Space Flight Center (MSFC) is currently investigating an electrolytic O2 recovery approach that will increase the O2 recovery to greater than 70 percent as well as lowering the complexity, mass, and power consumption than most other technologies currently under development. The electrolytic O2 recovery system consists of a Microfluidic Electrochemical Reactor (MFECR) that is based on the electrochemical reduction of CO2 to O2 and ethylene (C2H4) using water (H2O) as precursor and operates at standard condition with a theoretical recovery rate of 73 percent. In 2016, NASA’s Game Changing Development Program awarded the University of Texas Arlington (UTA) a grant to initiate the development of the MFECR. Since 2019, MSFC and UTA have been collaborating with the current goals of increasing the O2 recovery efficiency, advancing the technology readiness to a Technology Readiness Level (TRL) 4, and maturing the system to process CO2 of one crew-member. Based on the results from UTA’s initial efforts, the following were identified as key areas of improvement in order to maximize O2 recovery for the system: further development of the anode material and cathode catalyst, model-based cell design optimization, and the addition of a separation system and fuel cell. This paper will present the current developmental efforts of the electrolytic system including MFECR design and overall system enhancements as well as results from single cell stack testing.

Brittany R Brown↗

Post-Flight Assessment Review (PFAR): Advanced Colloids Experiment (ACE) ACE-T7-1,2

The objective of this PFAR is to: • Provide closure to ZIN DO-237 ACE-T7work and close NASA NPR 7123.1 requirements as listed in the SpaceDOC-II (S2) contract (the S2 CDRL DID No. PM-09 calls for a SEMP which refers backto NPR 7123.1) • Provide closure of SEMP (ZIN’s P40025) requirements for Technical Reviews • Provide plan to complete Informatics requirements. • Provide milestone closure to sponsoring organization. • Document property re-use and transfer decisions. • Transfer raw science data to the designated repository at MSFC. • Transfer required documents to Informatics • Opens an Informatics folder at MSFC to officially receive ACE-T7 information. • Capture open action items. • Create a formal presentation in configuration control. • Provide directions (in a Project Manager Report) how to contact the Project and Science teams through NASA when follow-on grants are awarded by Informatics.

microgravity↗

Design of an Excavation Robot: Regolith Advanced Surface Systems Operations Robot (RASSOR) 2.0

To continue on a sustainable and flexible path, NASA needs to address the challenge of collecting and moving large amounts of regolith at the destination. Acquiring the water resources on Mars will require mining significant quantities of regolith and this is not possible with the state-of-the-art low mass excavation systems. Low gravity environments (Mars = 3/8 G) and launch mass restrictions limit the traction and the resulting reaction force of the vehicle, making current terrestrial techniques impractical. This project addressed this challenge by developing a completely new technology that can mine large quantities of regolith on Mars. Recent measurements by the “Curiosity” rover on Mars have found that the regolith contains ~ 2% water by weight globally, ~4% in Jezero Crater (Human Architecture Team’s reference landing site), and much more at the poles(Leshin et al, 2013). RASSOR 2.0 is a planetary excavator, which has a mass of 66 kg, with a 0.38 kg vehicle mass per kilogram, per hour of excavation rate and power usage of 4 W per kg of regolith excavation rate. A single RASSOR 2.0 can excavate a minimum of 2.7 metric tons of regolith per day.This is accomplished by using counteracting excavation forces on two opposing digging implements called bucket drums and an autonomous mining control system. This work has addressed several major research areas outlined in the NASA Technology Area (TA) 04 Robotics & Autonomous Systems and TA 07 Human Destination Systems roadmaps. This project started at Technology Readiness Level (TRL) 4 as a low fidelity “proof of concept” prototype which has successfully demonstrated basic regolith simulant excavation functionality in a lab-scale gravity off load test. The foundational technology described here was awarded US patent number: US 9027265 for a “Zero horizontal reaction force excavator” on May 12, 2015.

RASSOR↗

Probabilistic Modeling of a Three-Stage Human Landing System Architecture

Space Policy Directive-1 has led to NASA partnerships with commercial entities on procurement which includes the development of the Human Landing System (HLS) [1]. With the goal of delivering human crew to the lunar surface by 2024, system uncertainties become an important obstacle to the maturation of multiple new, driving technologies and mission concepts of the HLS program. As unmitigated uncertainties have previously led to failed development programs, these risks and their impacts must be understood and handled to ensure program success [2]. Sources of uncertainty include novel engine designs and configurations, increased reliance on cryogenic fluid management(CFM), and refueling technologies—which propagate as high-level performance metrics such as overall propellant mass and engine performance. Also, the occurrence of operational uncertainties—e.g. launch conditions or need to abort during the mission—can cause cascading effects on the rest of the mission that are difficult to definitively quantify, and are outside the scope of control. These concrete examples and other occurrences can be categorized as either epistemic or aleatory uncertainties.Epistemic uncertainty arises due to a lack of knowledge and can be alleviated with design and program maturation. Aleatory uncertainty is due to the inherent randomness of the system and cannot be directly reduced, unlike epistemic uncertainty. Robust design and probabilistic methods can compensate for aleatory effects. A taxonomy of uncertainty is referred to for this work [3]. In this paper, a probabilistic methodology to handle uncertainties has been demonstrated on a three-element HLS concept [1, 4], which allows tracking of current best estimates of the concept and assessment of concept design robustness against uncertainties. A sample case has been completed for this abstract, and an expansion on the methodology will be included in the final paper. This methodology has two key parts: first, the creation of a dynamic architecture model of a three-element HLS concept; and second, its use with surrogate modeling and range estimating techniques to capture and propagate uncertainties. This abstract will cover the basics of the approach used, and further details and justifications will be in the final paper.The mission profile associated with this three-element concept (Fig 1) was modeled as a set of mission events that facilitated mass changes, idles, or spacecraft maneuvers. The mission profile scope starts with each element’s NRHO orbit insertion and aggregation and ends at post-sortie rendezvous with Orion. More detail on the mission profile will be in the final paper. The DYnamic Rocket EQuation Tool (DYREQT), a space systems synthesis and sizing framework used by NASA, was used as the physics framework to model the HLS architecture for applying the probabilistic methodology [5, 6]. Specifically, a parametric representation of the lander, ascent, and transfer elements and the mission profile of each element was established, with vehicle and mission parameters available as inputs to allow for a dynamic model. Each vehicle stage was modeled with high-level performance metrics, using Isp and propellant mass fraction (PMF) to remain parametric. For the probabilistic analysis, uncertainties of interest within the HLS concept were enumerated and represented as parameters within the DYREQT model as inputs for vehicle stages or mission profile events. These parameters were frozen at their nominal values for the purposes of baselining architecture performance and sizing the vehicle appropriately based on reference documentation [1]. Range estimating—a probabilistic method that combines Monte Carlo sampling, focus on critical parameters, and heuristics to assess risk and opportunities—is traditionally used with Mass Equipment Lists (MELs), but has been adapted with operational parameters as well as vehicle parameters in theDYREQT model to capture mission uncertainty alongside vehicle uncertainty [7, 3]. This method was selected due to its application and insight on a system from a bottom-up perspective, independence from historical rules of thumb, and ability to generate sensitivities based on design decisions and uncertainties. As a sample case for the abstract, the boiloff rates of the vehicle elements and the loiter times during the mission (simulating launch time variations and changing window of opportunities) were used with range estimating to provide preliminary results. To perform the range estimation portion of this methodology (depicted in Fig. 3, further details in final paper), the DYREQT model was sampled using a Design of Experiments (DoE) to efficiently explore the architecture design space with respect to the sample set of uncertainty parameters; 5,000 cases via Latin Hypercube Sampling were computed on the DYREQT architecture model. Then, the results were used to create surrogate models, multivariate regressions that can visualize hypercube trends in the design space, of the architecture with respect to the uncertainty parameters. Range estimating was applied to the surrogates instead of the actual models, which saves computational expense due to the bulk of cases needed for the Monte Carlo simulation as part of range estimating. Uncertainty parameters were sampled independently from triangular distributions using the DoE ranges as ‘min’ and ‘max’, and the nominal value as ‘most likely’. Based engineering intuition, some uncertainty parameters are correlated—e.g. if the main propellant has a high boil-off rate, the oxidizer should follow suit as both are related to CFM technology.While a Monte Carlo simulation samples all inputs as independent, the results would show model correlations; thus, it is efficient to sample the inputs as correlated. Using a correlation matrix constructed for the uncertainty parameters, previously independent samples were transformed to perform a Correlated Monte Carlo. A table for the DoE ranges and probability distribution parameters is shown in Table 1, and more details on Correlated Monte Carlo Simulations will be discussed in the final paper. The model’s resulting DoE showed that multivariate polynomial equations fit via least squares method captured its behavior accurately for the sample case. For the Correlated Monte Carlo Simulation, a positive correlation between fuel and oxidizer boiloff rates was used as a demonstration. 10,000 cases were computed with the surrogates and the launched masses for each vehicle element was collated. The results can be displayed in a probability density function (PDF), showing the impact of the uncertainty parameters chosen. Integrating the PDFs will yield a cumulative distribution function (CDF) that shows the cumulative probability of a given value on the x-axis. For the sample case, the elements’ launch mass margin was calculated and represented in as CDFs, as a demonstrated representation of figures of merit for the HLS concept. For the lander and ascent elements, the NRHO mass insertion limit is 16t; the transfer element has a limit of 30t [1]. It can be seen with Figure 2 that this probabilistic methodology can provide insight into mass margin with respect to the uncertainties being modeled. Currently, the results show that the lander (descent) vehicle element has the most restrictive design space; it is the only element to show a 10% probability of negative margin. Further analysis on the Monte Carlo results will show sensitivities for driving constraints and parameters for architecture feasibility, which can lead to establishing potential mission rules.The combination of range estimating with a parametric architecture model for HLS demonstrated the capability of this probabilistic methodology in a sample case. As the HLS development progresses, this methodology has the potential for keeping current best estimates of architecture performance for awarded concepts due to the flexibility in DYREQT’s modeling framework and its parametric nature. Concept maturation and increased epistemic knowledge can be injected into the model probabilistic modeling, and thus continue to track probability of mission success.

Stephanie Y Zhu↗

The Eris/Dysnomia System I: The Orbit of Dysnomia

We present new results on the Eris/Dysnomia system including analysis of new images from the WFC3 instru-ment on the Hubble Space Telescope (HST). Seven HST orbits were awarded to program 15171 in January and February 2018, with the intervals between observations selected to sample Dysnomia over a full orbital period. Using relative astrometry of Eris and Dysnomia, we computed a best-fit Keplerian orbit for Dysnomia. Based on the Keplerian fit, we find an orbital period of 15.785899±0.000050 days, which is in good agreement with recent work. We report a non-zero eccentricity of 0.0062 at the 6.2-σ level, despite an estimated eccentricity damping timescale of ≤17 Myr. Considering the volumes of both Eris and Dysnomia, the new system density was calculated to be 2.43±0.05 g cm3, a decrease of ~4% from the previous value of 2.52±0.05 g cm3. The new astrometric measurements were high enough precision to break the degeneracy of the orbit pole orientation, and indicate that Dysnomia orbits in a prograde manner. The obliquity of Dysnomia’s orbit pole with respect to the plane of Eris’ heliocentric orbit was calculated to be 78.29±0.65∘ and is in agreement with previous work; the next mutual events season will occur in 2239. The Keplerian orbit fit to all the data considered in this investi-gation can be excluded at the 6.3-σ level, but identifying the cause of the deviation was outside the scope of this work.

B J Holler↗

The Effects of Simulated Microgravity and PLacental-EXpanded (PLX-PAD) Stromal Cell Treatment on The Behavior and Correlation with Cytokine Profiles in Female Mice

Spacelight can lead to altered immune responses and inflammation (Crucian et al. 2014) and elevated levels of inflammation are connected to anxiety and depression. A recent study on the International Space Station showed that mice exhibited a novel circling behavior during spaceflight (Ronca 2019). However, there is still a gap in knowledge on how microgravity impacts behavior. In this current study, we performed 30 days of hindlimb unloading (HU) on four-month old female mice and analyzed select behavior from video image capture. We also determined the effects of PLacental-eXpanded stromal cells dervided from the maternal placenta (PLX-PAD), alone and in combination with HU and isolation, on behavior. We have previoulst shown that PLX-PAD mitigated select inflammatory responses and changes in cytokine expression causes by HU. In-cage behaviors were analyzed in HU or control female mice treated with 2 injections of PlasmaLyte (Sham) or PLX-PAD (n=7/group). We found that PLX-PAD decreased exploratory behaviors compared to Sham treated mice at night. Normally loaded (NL) PLX mice slept less than NL Sham mice during the day, and HU animals had signficantly higher involuntary movement during sleep compared to NL animals, suggesting sleep distruption. Overall, we show that both HU and PLX affect important behavioral factors., This experiment is the first to study the effects of PLX-PAD on behavior. Additional studies are needed to define the behavioral changes in spaceflight and test possible countermeasures. Funding for this project was provided through the 2019 Ames Research Innovation Award (ARIA) provided by NASA Ames Research Center.

Stromal cell treatment↗

GA-ASI Final Report and Program Wrap-up for NASA System Integration and Operationalization (SIO)

The NASA SIO demonstration flight of April 3, 2020 represents a successful culmination of 18 months of coordinated effort between GA-ASI, NASA, the FAA, Collins Aerospace, and Honeywell Aerospace to operate a Medium Altitude, Long Endurance (MALE) Unmanned Aircraft System (UAS) safely in the National Airspace System (NAS) using industry leading prototype technologies. The GA-ASI team consisted of technical experts, program managers, engineers, mechanics, flight technicians, flight crews, and numerous other subject matter experts. This final report describes the most significant and potentially impactful aspects of the planning, integration, test, and flight aspects of this effort. GA-ASI successfully integrated the key technologies needed for UAS to fly in the NAS onto our prototype SkyGuardian UAS, which was designed to meet the most stringent airworthiness standards applicable to an aircraft of its size category. A proven Detect and Avoid (DAA) system, developed by GA-ASI and utilizing Honeywell Aerospace technology was integrated onto SkyGuardian for the first time, along with datalink radios from Collins Aerospace that meet the new civil standard for Control and Non-Payload Communication (CNPC) links. GA-ASI also obtained approvals from the FAA and FCC to operate the reconfigured UAS. The SIO demonstration flight represented a commercial aerial surveying operation conducted at medium altitude (>10,000ft above mean sea level). The aircraft’s onboard sensors were used to capture photographic, infrared and radar imagery of public and commercial infrastructure and land, and to subsequently produce the types of data products that would provide business value to potential customers. These survey services would supplement or replace services currently provided by manned airplanes and helicopters, small drones or satellites. A “virtual” mission was also planned, to show what additional survey data could have been captured during the flight if additional sensors had been installed on the aircraft’s external hardpoints. This revision of the final report focuses on information of value to the wider UAS community, and avoids propriety data to facilitate broad dissemination. It also includes a description of GA-ASI’s engagement with the FAA following the SIO flight, which led to the award of an updated Special Airworthiness Certificate in the Experimental Category (SAC-EC) and a Certificate of Waiver or Authorization (COA) allowing operation of the SkyGuardian UAS using its DAA system to satisfy right-of-way rules, instead of a chase plane. The associated operational limitations are described to illustrate the further steps that would be needed to remove those limitations for unhindered commercial operations.

Flight demonstration↗

Series Bosch Carbon Formation Reactor Trade Study and Down-Select

Human exploration missions to Mars and other destinations beyond low Earth orbit require highly robust, reliable, and maintainable life support systems that maximize the recovery of oxygen (O2). One process in development and under consideration is the Series-Bosch System (S-Bosch). This system is a two stage reactor process that reduces carbon dioxide (CO2) with hydrogen (H2) to produce water and solid carbon. Theoretically, the Bosch process can recover 100% of the O2 from CO2 in the form of water, making it an attractive option for long duration missions. The Series Bosch system includes a reverse water gas shift (RWGS) reactor, a carbon formation reactor (CFR), a H2 extraction membrane, and a CO2extraction membrane. To further the development of oxygen recovery systems, NASA awarded Phase I contracts to several entities under the Game Changing Development Program addressing Spacecraft Oxygen Recovery (SCOR). Two of the hardware deliverables were integrated into the Carbon Dioxide Reduction Test Stand (CORTS) as carbon formation reactors and performance evaluations were executed at Marshall Space Flight Center. A trade study was performed between these two reactors along with one developed at MSFC. This paper provided the necessary information for the Advanced Exploration Systems/Life Support Systems Project (AES/LSS) managers to select a CFR for further development and discusses the process of selection.

Bosch↗