Engineering Papers⌕ Search

SEARCH · Engineering Papers

Results for “radiators”

Search indexed NASA NTRS and DOE OSTI research on propulsion, heat transfer, battery materials and energy systems. Follow report and document links to the original sources.

Quote a phrase for an exact phrase match. Source license links do not imply unrestricted reuse.

At least 829 records · Page 46
All sourcesNASA NTRSDOE OSTI
DOE OSTI2023

The Influence of Cloud Types on Cloud–Radiative Forcing During DYNAMO/AMIE

Cloud-radiative feedback is known to be an important process for the Madden-Julian Oscillation (MJO) and its accurate representation in general circulation models. The MJO is known to have a stronger cloud-radiative feedback compared to higher frequency convectively coupled equatorial waves (CCEW), for reasons that remain unclear. The objective of this study is to use data from the Dynamics of the MJO/Atmospheric Radiation Measurement MJO Investigation Experiment field campaign to investigate how cloud type evolution and their associated cloud-radiative forcing (CRF) differ between the MJO and CCEWs and their application to MJO dynamics under moisture mode theory. This study finds that the amplitude of CRF is the largest within the MJO compared to the higher frequency CCEWs, and CRF maximizes after the maximum precipitation (enhanced phase) of the MJO. We suggest this delay in the timing of maximum CRF occurs because most cloud types (congestus, deep, anvil, and cirrus) simultaneously maximize in frequency after the enhanced phase of the MJO, which is not seen for the higher frequency CCEWs. These specific cloud types help maintain the MJO through their radiatively-driven moistening which acts to prolong the enhanced phase of the MJO. The decomposition of radiatively-driven moistening by cloud types shows that simultaneous moistening by deep, anvil, and congestus clouds are particularly responsible for the maintenance of the MJO under moisture mode theory. Further, this analysis suggests the importance of capturing the correct evolution of different cloud types and their associated radiative effects to better understand the thermodynamics of the MJO.

54 ENVIRONMENTAL SCIENCES↗
DOE OSTI2025

Achievement of highly radiating plasma in negative triangularity and effect of reactor-relevant seeded impurities on confinement and transport

The first achievement of highly radiating plasmas in negative triangularity (NT) is shown with an operational space featuring high core radiation at high Greenwald fraction obtained with the injection of reactor-relevant seeded gases. These NT shape diverted discharges reach high values of normalized plasma pressure ( β N > 2) at high radiation fraction with no edge localized modes (ELMs) and a simultaneous reduction of the divertor heat flux. Here, we demonstrate that as long as the impurity level in the core is kept low to avoid excessive fuel dilution and impurity accumulation, integration of NT configuration with high radiation fraction not only is achievable but it can lead to confinement improvement with stabilization effects originating from collisionality, E × B shear and profiles changes due to impurity radiation cooling. The underlying physics mechanism is robust and reproducible and holds for a variety of impurity species. The absence of the requirement to stay in H-mode translates in a higher core radiation fraction potentially allowed in NT shape effectively mitigating the power exhaust issue. The results presented here demonstrate a path to high performance, ELM free and highly radiative regime with reactor-relevant seeding gases making this regime a potential new scenario for reactor design.

confinement improvement↗
DOE OSTI2026

Radiative divertor detachment and impurity transport with nitrogen and neon seeding in KSTAR H-mode plasmas

Achieving core-edge compatible divertor detachment is a critical requirement for stable operation in future fusion devices. This study compares nitrogen and neon seeding in KSTAR H-mode plasmas with carbon walls, combining experiments and SOLPS-ITER modelling to evaluate their radiative dissipation and core-edge compatibility. Experimentally, N seeding achieved stronger divertor detachment, with larger reductions in target particle and heat fluxes, a higher divertor radiation fraction, and a lower core radiation fraction than Ne. In contrast, Ne seeding triggered a significant rise in core radiation followed by H–L back transitions, limiting the maximum total radiated power fraction to roughly half that of N. SOLPS-ITER simulations reproduced the experimental trends and revealed that the better core-edge compatibility of N arises from its higher divertor retention in addition to its higher cooling factor. The relative positions of the stagnation points of impurity poloidal velocity and ionization sources did not explain the different divertor compression. Instead, in the present modelling, the higher impurity parallel particle flux, resulting from the higher parallel impurity velocity, explains the stronger nitrogen impurity compression in the divertor region. The parallel temperature distribution with N was more favourable for achieving higher impurity parallel velocity than with Ne, because the impurity velocity is governed by modifications of the main ion flow due to friction and thermal forces, both of which strongly depend on the temperature. Ultimately, this behaviour is attributed to the strongly divertor-localized radiation of N. These results demonstrate that N is more effective than Ne in achieving radiative divertor detachment while maintaining low core contamination in KSTAR, consistent with observations in other present tokamaks.

KSTAR↗
DOE OSTI2022

MECHANISMS OF RADIATION CARCINOGENESIS: WHAT IS REALLY INDUCED?

Abstract It has been difficult to understand why the relative risk for cancer decreases with an increase in time since an exposure to radiation. It was recently recognized that this decline can be explained by a parallel shift of the age-related cancer mortality curve toward younger ages. In fact, it has been known for many years that mouse survival curves exhibit a parallel shift toward younger ages following an exposure to radiation, but it was not recognized that the mutation induction theory is incompatible with this parallel shift. This is because a parallel shift in the survival curve implies that all the irradiated individuals are affected, but the mutation induction theory assumes that only a fraction of the irradiated individuals is affected following an exposure to radiation. Thus, it seems likely that the target of radiation action, which leads to carcinogenesis, is not restricted to epithelial cells but includes all of the surrounding cells leading to an altered microenvironment. Since it is repeatedly observed that radiation-exposed normal tissues can stimulate transplanted or spontaneously arising tumor cells to grow faster, worsen the malignant phenotypes and finally kill the host earlier than usual, an exposure to radiation seems most likely to cause tissue inflammation, which creates conditions favorable for the growth of spontaneously arising tumor cells. This new concept suggests that it might be possible to attenuate the extent of radiation carcinogenesis by intervening in tissue inflammatory processes.

38 RADIATION CHEMISTRY, RADIOCHEMISTRY, AND NUCLEA↗
DOE OSTI2021

Coupled Charge and Radiation Transport Processes in Thermophotovoltaic and Thermoradiative Cells

Accurate modeling of charge transport and both thermal and luminescent radiation is crucial to the understanding and design of radiative thermal energy converters. Charge-carrier dynamics in semiconductors are well-described by the Poisson-drift-diffusion equations, and thermal radiation in emitter-absorber structures can be computed using multilayer fluctuational electrodynamics. These two types of energy flows interact through radiation absorption or luminescence and charge-carrier generation or recombination. However, past research has typically only assumed limited interaction, with thermal radiation absorption as an input for charge-carrier models to predict device performance. To examine this assumption, we develop a fully coupled iterative model of charge and radiation transport in semiconductor devices, and we use our model to analyze near-field and far-field GaSb thermophotovoltaic and thermoradiative systems. By comparing our results with past methods that do not consider cross-influences between charge and radiation transport, we find that a fully coupled approach is necessary to accurately model photon recycling and near-field enhancement of external luminescence. As these effects can substantially alter device performance, our modeling approach can aid in the design of efficient thermophotovoltaic and thermoradiative systems.

30 DIRECT ENERGY CONVERSION↗
DOE OSTI2024

Investigation of Thermal Radiation under Pressurized Oxy-combustion Conditions

Thermal radiation of the gaseous and particle phases in a pilot-scale pressurized oxy-combustor is computationally studied. In particular, the radiation characteristics of gases and particles are estimated by employing the statistical narrow-band model and the large-particle model. It is found that thermal radiation of the particle cloud dominates in the combustor under a furnace temperature of 1500 K and when there is no substantial loss of particles to the walls. Another important observation is that radiation from the gas and particles can be approximately treated as a graybody under these conditions. More specifically, the results on the spectral radiation intensity of a gas comprising 40% (vol) H 2 O and 60% CO 2 show that when the pressure is increased to 15 bar, and the radiation pathlength is 100 cm, the spectral radiation profile of the gas phase approaches that of a blackbody at the respective temperature. In addition, the emissivity of the particulate cloud has been evaluated as a function of the particle concentration and diameter by employing the large-particle model. It is shown that the emissivity grows with the particle concentration but decreases with the particle size for the same mass of the particles. Finally, this outcome of the present study is expected to be used to validate the assumption of the gray-gas model adopted in the numerical simulations of pressurized oxy-combustion.

large-particle model↗
DOE OSTI2021

Collaborative Research: Improved Efficiency and Coupling of the Radiation Code in the ACME Earth System Model (Final Report)

The complexity of radiative transfer, its importance to the exchange of energy in the climate system, and its high computational cost establishes importance of an accurate and efficient radiative transfer parameterization for climate simulation. Previous work by the proposing team at AER led to the development of the radiation code, RRTMG, which has been widely accepted by the global modeling community as a fast and accurate advancement over the previous generation of radiation codes. It has been in use in the NCAR CESM for many years, and it has been implemented in the initial version the DOE E3SM model. However, its computational cost remains high relative to other components in part due to its complexity and to its inefficient use of modern optimization strategies, and this project helped address this limitation for the code’s application in E3SM. Under other funding, the Investigators of this project led an effort to develop a high-performance broadband radiation code, called RTE+RRTMGP, which is a completely restructured code that will take advantage of modern computational capabilities to enhance its performance while retaining the strengths and accuracy of the original code. Designed to perform over a range of computer architectures, RTE+RRTMGP makes extensive use of Fortran 2003 features to improve both its efficiency and its use of memory. RTE+RRTMGP is expected to be adopted in the next generation of RTE+RRTMGP. This project allowed for advancements to the code’s computational capabilities and adding new and enhanced features. This included revising RTE+RRTMGP to run on GPU processors, analysis of and improvements to the code’s timing, modifying the gas optics in RRTMGP to increase the code’s accuracy, extensive validation of computed fluxes, heating rates and forcings, generating a cloud optical property and vertical sampling capabilities for RTE+RRTMGP, implementing a fast and accurate longwave scattering capability, and groundwork for the inclusion of a capability to specify solar variability. Many of the accomplishment in this project necessitated significant collaboration with the E3SM development team. The result of this project was optimization of a key physical component (radiative transfer calculations) of E3SM, directly supporting E3SM’s overarching global modeling objectives. More broadly, this project provided overall advancements in the use of radiative transfer calculations in atmospheric modeling and simulation, particularly for climate.

58 GEOSCIENCES↗
DOE OSTI2021

X-Ray Spectroscopic Studies of X-Pinch Plasmas with 3-5 Picosecond Resolution: A Quest for Clear Experimental Evidence for Radiative Collapse in the X-ray Spectra (Final Report)

Dense Z-pinch plasmas produced from current-carrying exploding wires frequently produce very brief (less than 0.1 nanosecond), intense, bursts of soft X-rays from tiny (about 1 micrometer), very hot (10-30 million K) regions of the plasma. This project addresses the physical processes that lead to those tiny, high-energy density plasmas and develops means to measure the conditions just before and during the X-ray bursts. One possible relevant process is radiative collapse, which starts if the power radiated by a dense Z-pinch, proportional to the density-squared, exceeds the resistive heating rate from the current flow, thereby cooling the plasma and enabling the magnetic pinching force to exceed the outward plasma thermal pressure. As the resulting radius reduction further increases the radiation rate, this process produces a runaway magnetic implosion. A competing mechanism is a sausage-like instability that can develop in a Z-pinch plasma at a lower current than is needed to induce radiative collapse. This mechanism can also produce tiny hot spots in the neck regions of the sausage-shaped plasma column. It is also possible that these two mechanisms work together to produce the X-ray emitting hot spots. If radiative collapse does contribute to hot spot formation, it would be terminated when the plasma becomes so dense that the radiation cannot escape, enabling the plasma kinetic pressure to build up and stop the current-driven implosion. This project aims to study the development of the hot spots by means of high temporal and spatial resolution X-ray spectroscopy to determine if there is evidence for the presence of the radiative collapse mechanism. Progress toward this goal is presented. To summarize, during the four-year period 09/15/2017 - 9/14/2021, we have collected necessary spectroscopic data to determine the plasma conditions and continue to do so. We are also now in the process of calibrating diagnostic systems (especially the x-ray streak camera system) and analyzing data to determine plasma conditions as a function of time before, during and after the X-ray burst.

70 PLASMA PHYSICS AND FUSION TECHNOLOGY↗
DOE OSTI2025

Hydrodynamic Coupling to a Homogenized Radiation Transport Method based on Young Measures

Resolving radiation transport fields subject to opacity profiles with strong, oscillatory line structure while potentially falling under intermediate optical depth conditions presents a numerical challenge in radiation transport modeling. The Young measure-based homogenization technique formulated by Haut et al. (2017) was investigated as a candidate method for resolving radiation fields under such conditions more accurately. The method was compared against frequently-utilized mean opacity methods as the Rosseland and Planck formulations. In this work, all methods were tested through radiation slab calculations separately comprised of aluminum, copper, and krypton, each for different thermodynamic conditions. Following these offline radiation slab calculations, demonstrations shifted towards the SCEPTRE radiation transport code and, subsequently, the multiphysics ALEGRA code for approximately-coupled radiation-material simulations. Throughout all the simulations shown in this study, for a fixed computational cost, the homogenized method was observed to be more accurate than any of the solutions determined through traditional mean opacity approaches.

73 NUCLEAR PHYSICS AND RADIATION PHYSICS↗
DOE OSTI2021

Numerical Analysis of Radiation Effects on Fiber Optic Sensors

Optical fiber sensors (OFS) are a potential candidate for monitoring physical parameters in nuclear environments. However, under an irradiation field the optical response of the OFS is modified via three primary mechanisms: (i) radiation-induced attenuation (RIA), (ii) radiation-induced emission (RIE), and (iii) radiation-induced compaction (RIC). For resonance-based sensors, RIC plays a significant role in modifying their performance characteristics. In this paper, we numerically investigate independently the effects of RIC and RIA on three types of OFS widely considered for radiation environments: fiber Bragg grating (FBG), long-period grating (LPG), and Fabry-Perot (F-P) sensors. In our RIC modeling, experimentally calculated refractive index (RI) changes due to low-dose radiation are extrapolated using a power law to calculate density changes at high doses. The changes in RI and length are subsequently calculated using the Lorentz–Lorenz relation and an established empirical equation, respectively. The effects of both the change in the RI and length contraction on OFS are modeled for both low and high doses using FIMMWAVE, a commercially available vectorial mode solver. An in-depth understanding of how radiation affects OFS may reveal various potential OFS applications in several types of radiation environments, such as nuclear reactors or in space.

42 ENGINEERING↗
DOE OSTI2020

The Role of Outflows, Radiation Pressure, and Magnetic Fields in Massive Star Formation

Stellar feedback in the form of radiation pressure and magnetically driven collimated outflows may limit the maximum mass that a star can achieve and affect the star formation efficiency of massive prestellar cores. Here we present a series of 3D adaptive mesh refinement radiation–magnetohydrodynamic simulations of the collapse of initially turbulent, massive prestellar cores. Our simulations include radiative feedback from both the direct stellar and dust-reprocessed radiation fields, and collimated outflow feedback from the accreting stars. We find that protostellar outflows punch holes in the dusty circumstellar gas along the star’s polar directions, thereby increasing the size of optically thin regions through which radiation can escape. Precession of the outflows as the star’s spin axis changes due to the turbulent accretion flow further broadens the outflow, and causes more material to be entrained. Additionally, the presence of magnetic fields in the entrained material leads to broader entrained outflows that escape the core. We compare the injected and entrained outflow properties and find that the entrained outflow mass is a factor of ∼3 larger than the injected mass and the momentum and energy contained in the entrained material are ∼25% and ∼5% of the injected momentum and energy, respectively. As a result, we find that, when one includes both outflows and radiation pressure, the former are a much more effective and important feedback mechanism, even for massive stars with significant radiative outputs.

79 ASTRONOMY AND ASTROPHYSICS↗
DOE OSTI2026

Radiation GRMHD Models of Accretion onto Stellar-mass Black Holes. II. Super-Eddington Accretion

We present a comprehensive analysis of super-Eddington black hole accretion simulations that solve the GRMHD equations coupled with angle-discretized radiation transport. The simulations span a range of accretion rates, two black hole spins, and two magnetic field topologies, and include resolution studies as well as comparisons with nonradiative models. Super-Eddington accretion flows consistently develop geometrically thick disks supported by radiation pressure, regardless of magnetic field configuration. Radiation generated in the inner disk drives substantial outflows, forming conical funnel regions that limit photon escape and result in very low radiation efficiency. The accretion flows are highly turbulent, with thermal energy transport dominated by radiation advection rather than diffusion. Angular momentum is primarily carried outward by Maxwell stress, with turbulent Reynolds stress playing a subdominant role. Both strong and weak jets are produced. Strong jets arise from sufficient net vertical magnetic flux and rapid black hole spin, and they can effectively evacuate the funnel, enabling radiation to escape through strong geometric beaming. In contrast, weak jets fail to clear the funnel, which becomes obscured by radiation-driven outflows and leads to distinct observational signatures. Spiral structures are observed in the plunging region, behaving like density waves. These super-Eddington models are applicable to a variety of astronomical systems, including ultraluminous X-ray sources, little red dots, and black hole transients.

79 ASTRONOMY AND ASTROPHYSICS↗
NASA NTRS1935

Drag of Prestone and Oil Radiators on the YO-31A Airplane

At the request of the Army Air Corps tests were conducted on a mock-up of the YO-31A airplane to determine the drag of the prestone and oil radiators. The drag of the airplane was determined with both radiators exposed on the lower surface of the fuselage; with each radiator exposed; and with no radiators. The results show that at 120 m.p.h the oil radiator accounted for 2.8 percent of the drag of the complete airplane; the prestone radiator 8.3 percent; and both radiators together, 11.8 percent.

RADIATORS - DOUGLAS YO-31A - DRAG↗
NASA NTRS1994

Monte Carlo prediction of radiative heat transfer in inhomogeneous, anisotropic, nongray media

A Monte Carlo solution technique has been formulated to predict the radiative heat transfer in three-dimensional, inhomogeneous participating media which exhibit spectrally dependent emission and absorption and anisotropic scattering. Details of the technique and selected numerical sensitivities are discussed. The technique was applied to a problem involving a medium composed of a gas mixture of carbon dioxide and nitrogen and suspended carbon particles. A homogeneous medium was modeled to examine the effect of total pressure and carbon-particle concentration on radiative heat transfer. Variation in total pressure, over the range studied, had minimal effect on the amount of heat radiated to the enclosure walls and on the radiative-flux distribution within the medium. Increases in the carbon particle concentration produced significantly higher heat fluxes at the boundaries and altered the radiative flux distribution. The technique was then applied to an inhomogeneous medium to examine effects of specific temperature and carbon particle concentration distributions on radiative heat transfer. For the inhomogeneous conditions examined, the largest radiative flux divergence occurs near the center of the medium and the regions near some enclosure walls act as energy sinks.

HEAT FLUXES↗
NASA NTRS2002

Radiation-induced gene expression in the nematode Caenorhabditis elegans

We used the nematode C. elegans to characterize the genotoxic and cytotoxic effects of ionizing radiation in a simple animal model emphasizing the unique effects of charged particle radiation. Here we demonstrate by RT-PCR differential display and whole genome microarray hybridization experiments that gamma rays, accelerated protons and iron ions at the same physical dose lead to unique transcription profiles. 599 of 17871 genes analyzed (3.4%) showed differential expression 3 hrs after exposure to 3 Gy of radiation. 193 were up-regulated, 406 were down-regulated and 90% were affected only by a single species of radiation. A novel statistical clustering technique identified the regulatory relationships between the radiation-modulated genes and showed that genes affected by each radiation species were associated with unique regulatory clusters. This suggests that independent homeostatic mechanisms are activated in response to radiation exposure as a function of track structure or ionization density.

Non-NASA Center↗
NASA NTRS2000

Clustered DNA damages induced in isolated DNA and in human cells by low doses of ionizing radiation

Clustered DNA damages-two or more closely spaced damages (strand breaks, abasic sites, or oxidized bases) on opposing strands-are suspects as critical lesions producing lethal and mutagenic effects of ionizing radiation. However, as a result of the lack of methods for measuring damage clusters induced by ionizing radiation in genomic DNA, neither the frequencies of their production by physiological doses of radiation, nor their repairability, nor their biological effects are known. On the basis of methods that we developed for quantitating damages in large DNAs, we have devised and validated a way of measuring ionizing radiation-induced clustered lesions in genomic DNA, including DNA from human cells. DNA is treated with an endonuclease that induces a single-strand cleavage at an oxidized base or abasic site. If there are two closely spaced damages on opposing strands, such cleavage will reduce the size of the DNA on a nondenaturing gel. We show that ionizing radiation does induce clustered DNA damages containing abasic sites, oxidized purines, or oxidized pyrimidines. Further, the frequency of each of these cluster classes is comparable to that of frank double-strand breaks; among all complex damages induced by ionizing radiation, double-strand breaks are only about 20%, with other clustered damage constituting some 80%. We also show that even low doses (0.1-1 Gy) of high linear energy transfer ionizing radiation induce clustered damages in human cells.

NASA Discipline Radiation Health↗
NASA NTRS2015

Radiative Heating on the After-Body of Martian Entry Vehicles

This paper presents simulations of the radiative heat flux imparted on the after-body of vehicles entering the Martian atmosphere. The radiation is dominated by CO2 bands emitting in the mid-wave infrared spectral region. This mechanism has traditionally not been considered in the design of past Mars entry vehicles. However, with recent analysis showing that the CO2 radiation can be greater than convective heating in the wake, and with several upcoming and proposed missions to Mars potentially affected, an investigation of the impact of this radiation is warranted. The focus of this paper is to provide a better understanding of the impact to aerothermal heating predictions and to provide comparisons between NASA's two main radiation codes, NEQAIR and HARA. The tangent slab approximation is shown to be overly conservative, by as much as 58 percent, for most back- shell body point locations compared to using a full angular integration method. However, due to the complexity of the wake flow, it is also shown that tangent slab does not always represent an upper limit for radiative heating. Furthermore, analysis in this paper shows that it is not possible to provide a general knock-down factor from the tangent slab results to those obtained using the more rigorous full integration method. When the radiative heating is accounted for on the after-body, the unmargined total heat flux can be as high as 14 watts per square centimeter.

After-body↗
NASA NTRS2016

Simulated Space Radiation: Murine Skeletal Responses During Recovery and with Mechanical Stimulation

Simulated space radiation at doses similar to those of solar particle events or a round-trip sojourn to Mars (1-2Gy) may cause skeletal tissue degradation and deplete stem/progenitor cell pools throughout the body. We hypothesized that simulated space radiation (SSR) causes late, time-dependent deficits in bone structure and bone cell function reflected by changes in gene expression in response to anabolic stimuli. We used a unique sequential dual ion exposure (proton and iron) for SSR to investigate time-dependence of responses in gene expression, cell function, and microarchitecture with respect to radiation and an anabolic stimulus of axial loading (AL). Male 16-wk C57BL6/J mice (n=120 total) were exposed to 0Gy (Sham, n=10), 56Fe (2Gy, positive control dose, n=10), or sequential ions for SSR (1Gy 1H/56Fe/1H, n=10) by total body irradiation (IR), and the tissues were harvested 2 or 6 mo. later. Further, to assess the response to anabolic stimuli, we subjected additional Sham-AL (n=15) and SSR-AL (n=15) groups to rest-inserted tibial axial loading (AL) starting at 1 and 5 months post-IR (-9N, 60 cycles/day, 3 days/wk, 4 wks). Exposure to 56Fe caused a significant reduction in cancellous bone volume fraction (BV/TV) compared to Sham (-34%) and SSR (-20%) in the proximal tibia metaphysis at 2-months post-IR; however BV/TV for SSR group was not different than Sham. Both 56Fe and SSR caused significant reduction in trabecular number (Tb.N) compared to Sham (-33% and -16%, respectively). Further, Tb.N for 56Fe (2Gy) was significantly lower than SSR (-21%). Ex vivo culture of marrow cells to assess growth and differentiation of osteoblast lineage cells 6 months post-IR showed that both 56Fe and SSR exposures significantly impaired colony formation compared to Sham (-66% and -54%, respectively), as well as nodule mineralization (-90% and -51%, respectively). Two-way analysis of variance showed that both mechanical loading and radiation reduced BV/TV, mechanical loading reduced trabecular thickness (Tb.Th), and radiation reduced Tb.N, at both time points. To assess acute response to mechanical stimuli, samples were harvested from a subset of Sham-AL (n=5) and SSR-AL (n=5) to measure changes in gene expression levels. Preliminary results indicate that axial loading increased expression of the antioxidant response gene Nfe2l2 and the osteoprogenitor-associated marker Runx2 in the bone marrow cells, and there was an interaction effect between axial loading and radiation at 2-months post-IR. Additional analyses of gene expression levels in the mineralized tissue are in progress. Results indicate that SSR caused persistent impairment of osteoblast colony formation and nodule mineralization 6-mo post-IR. Contrary to our hypothesis, simulated space radiation did not impair the ability of cancellous bone to respond to a mechanical anabolic stimulus, consistent with our previous findings [1]. Hence, compressive loading may be a potential countermeasure against spaceflight-induced bone loss.

Bone Loss↗