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An Overview of SBIR Phase 2 Physical Sciences and Biomedical Technologies in Space

Technological innovation is the overall focus of NASA's Small Business Innovation Research (SBIR) program. The program invests in the development of innovative concepts and technologies to help NASA's mission directorates address critical research and development needs for agency projects. This report highlights innovative SBIR Phase II projects from 2007-2012 specifically addressing areas in physical sciences and biomedical technologies in space, which is one of six core competencies at NASA Glenn Research Center. There are twenty two technologies featured with emphasis on a wide spectrum of applications such as reusable handheld electrolyte, sensor for bone markers, wideband single crystal transducer, mini treadmill for musculoskeletal, and much more. Each article in this report describes an innovation, technical objective, and highlights NASA commercial and industrial applications. This report serves as an opportunity for NASA personnel including engineers, researchers, and program managers to learn of NASA SBIR's capabilities that might be crosscutting into this technology area. As the result, it would cause collaborations and partnerships between the small companies and NASA Programs and Projects resulting in benefit to both SBIR companies and NASA.

electrolytes↗

2010 NASA Exploration Systems Mission Directorate: Lunabotics Mining Competition Systems Engineering Paper

A fast growing approach in determining the best design concept for a problem is to hold a competition in which the rules are based on requirements similar to the actual problem. By going public with such competitions, sponsoring entities receive some of the most innovative engineering solutions in a fraction of the time and cost it would have taken to develop such concepts internally. Space exploration is a large benefactor of such design competitions as seen by the results of X-Prize Foundation and NASA lunar excavation competitions [1]. The results of NASA's past lunar excavator challenges has led to the need for an effective means of collecting lunar regolith in the absence of human beings. The 2010 Exploration Systems Mission Directorate (ESMD) Lunar Excavation Challenge was created "to engage and retain students in science, technology, engineering, and mathematics, or STEM, in a competitive environment that may result in innovative ideas and solutions, which could be applied to actual lunar excavation for NASA." [2]. The ESMD Challenge calls for "teams to use telerobotics or autonomous operations to excavate at least 10kg of lunar regolith simulant in a 15 minute time limit" [2]. The Systems Engineering approach was used in accordance with Auburn University's mechanical engineering senior design course (MECH 4240-50) to develop a telerobotic lunar excavator, seen in Fig. 1, that fulfilled requirements imposed by the NASA ESMD Competition Rules. The goal of the senior design project was to have a validated lunar excavator that would be used in the NASA ESMD lunar excavation challenge.

Source record↗

Xenon Acquisition Strategies for High-Power Electric Propulsion NASA Missions

The benefits of high-power solar electric propulsion (SEP) for both NASA's human and science exploration missions combined with the technology investment from the Space Technology Mission Directorate have enabled the development of a 50kW-class SEP mission. NASA mission concepts developed, including the Asteroid Redirect Robotic Mission, and those proposed by contracted efforts for the 30kW-class demonstration have a range of xenon propellant loads from 100's of kg up to 10,000 kg. A xenon propellant load of 10 metric tons represents greater than 10% of the global annual production rate of xenon. A single procurement of this size with short-term delivery can disrupt the xenon market, driving up pricing, making the propellant costs for the mission prohibitive. This paper examines the status of the xenon industry worldwide, including historical xenon supply and pricing. The paper discusses approaches for acquiring on the order of 10 MT of xenon propellant considering realistic programmatic constraints to support potential near-term NASA missions. Finally, the paper will discuss acquisitions strategies for mission campaigns utilizing multiple high-power solar electric propulsion vehicles requiring 100's of metric tons of xenon over an extended period of time where a longer term acquisition approach could be implemented.

Electric Propulsion↗

Standard Component Commodity Usage Guides (CUGs) for Charge-Coupled Devices (CCDs)

Communicating risk and reliability information within NASA Goddard’s missions is crucial to continuing the development of new technology and ensuring GSFC missions achieve their science objectives. The Reliability and Risk Assessment Branch (Code 371) within the SMA directorate is one of GSFC’s leaders in communicating this information to missions, and one tool 371 engineers use to provide this information is the Commodity Usage Guides (CUGs). CUGs are helpful in compiling various critical parameters and heritage information for standard payload components, ensuring project personnel inherit the lessons learned from previous experiences. The purpose of this project was to create CUGs for CCDs used within GSFC missions. To formulate a CUG applicable data was aggregated into the CUG template for Charge-Coupled Devices (CCDs)--electro-optical components used to convert photons into digital images and data. CCDs can easily be adapted to a variety of mission requirements making them widely used at GSFC, and therefore suitable for CUGs. Once the CUGs for CCDs are completed the information can be distributed to engineers, scientists and other project members to ensure the lessons learned are passed on to the next mission.

Christman, Jerika H.↗

Plutonium workers get a new level of education in the actinide mission

The Associate Laboratory Directorate for Weapons Production (ALDWP) and the National Security Education Center (NSEC) have teamed to develop a new Nuclear Enterprise Science and Technology (NEST) Academic Certificate program offered through the University of New Mexico – Los Alamos (UNM-LA). The pilot program, which virtually kicked off on January 19 even amidst snow closures, received accreditation by the State Higher Education Department (HED) in FY20 and is designed for LANL’s existing fissile material handler technician and technologist employee workforce. It will provide essential science, operations, and business education on all aspects of working in modern nuclear materials handling and processing facilities. The first course for the certificate program is called “Nuclear Facility Fundamentals.” A call for nominations went out to the directorate and a cohort of 15 individuals has been established to start the program.

61 RADIATION PROTECTION AND DOSIMETRY↗

Design of nematic liquid crystals to control microscale dynamics

The dynamics of small particles, both living such as swimming bacteria and inanimate, such as colloidal spheres, has fascinated scientists for centuries. If one could learn how to control and streamline their chaotic motion, that would open technological opportunities in the transformation of stored or environmental energy into systematic motion, with applications in micro-robotics, transport of matter, guided morphogenesis. This review presents an approach to command microscale dynamics by replacing an isotropic medium with a liquid crystal. Orientational order and associated properties, such as elasticity, surface anchoring, and bulk anisotropy, enable new dynamic effects, ranging from the appearance and propagation of particle-like solitary waves to self-locomotion of an active droplet. By using photoalignment, the liquid crystal can be patterned into predesigned structures. In the presence of the electric field, these patterns enable the transport of solid and fluid particles through nonlinear electrokinetics rooted in anisotropy of conductivity and permittivity. Director patterns command the dynamics of swimming bacteria, guiding their trajectories, polarity of swimming, and distribution in space. This guidance is of a higher level of complexity than a simple following of the director by rod-like microorganisms. Namely, the director gradients mediate hydrodynamic interactions of bacteria to produce an active force and collective polar modes of swimming. The patterned director could also be engraved in a liquid crystal elastomer. When an elastomer coating is activated by heat or light, these patterns produce a deterministic surface topography. The director gradients define an activation force that shapes the elastomer in a manner similar to the active stresses triggering flows in active nematics. Finally, the patterned elastomer substrates could be used to define the orientation of cells in living tissues. The liquid-crystal guidance holds a major promise in achieving the goal of commanding microscale active flows.

36 MATERIALS SCIENCE↗

Facility Safety Plan – Building 225

B225 is operated by the Weapons and Complex Integration (WCI) Directorate and is classified as a Low Hazard facility for radiological hazards and Light Science Industry (LSI) for chemical, radiation generating devices (RGDs) and industrial hazards. Explosives and biological hazards are not authorized for B225. B225 is located in the southwest quadrant of Lawrence Livermore National Laboratory (LLNL) less than 600 meters from the nearest site boundary. B225 is a single-story concrete tilt-up building with a steel deck roof. The primary mission of this facility is to apply nondestructive evaluation (NDE) methods to materials, components, and assemblies. B225 also contains the polymer additive manufacturing laboratories. The floor plans for B225 are provided in Appendix A.

99 GENERAL AND MISCELLANEOUS↗

ASK Talks with Dennis Grounds

Dennis Grounds recently finished a one-year assignment at NASA Headquarters in the Office of Bioastronautics as the Acting Flight Program Manager He has returned to Johnson Space Center (JSC), where he is Director of the International Space Station Bioastronautics Research Program Office with the NASA Life Sciences Projects Division. Under his management, the Human Research Facility (HRF) was developed to support a broad range of scientific investigations pertaining to human adaptation to the spaceflight environment and issues of human space exploration. The HRF rack was developed to international standards in order to be compatible with payloads developed anywhere in the world, thereby streamlining the process of getting payloads on the Space Station. Grounds has worked with NASA for more than 15 years. Prior to joining ISS, he worked with General Electric as a manager of payloads and analysis in support of the NASA Life Science Projects Division at JSC. ASK spoke with Grounds in Washington, D.C., during his Headquarters assignment.

Source record↗

NASA Centers and Universities Collaborate Through Smallsat Technology Partnerships

The Small Spacecraft Technology (SST) Program within the NASA Space Technology Mission Directorate is chartered develop and demonstrate the capabilities that enable small spacecraft to achieve science and exploration missions in "unique" and "more affordable" ways. Specifically, the SST program seeks to enable new mission architectures through the use of small spacecraft, to expand the reach of small spacecraft to new destinations, and to make possible the augmentation existing assets and future missions with supporting small spacecraft. The SST program sponsors smallsat technology development partnerships between universities and NASA Centers in order to engage the unique talents and fresh perspectives of the university community and to share NASA experience and expertise in relevant university projects to develop new technologies and capabilities for small spacecraft. These partnerships also engage NASA personnel in the rapid, agile and cost-conscious small spacecraft approaches that have evolved in the university community, as well as increase support to university efforts and foster a new generation of innovators for NASA and the nation.

Partnerships↗

Argonne National Laboratory Annual Report of Laboratory Directed Research and Development Program Activities FY 2012

Our plans to upgrade the Advanced Photon Source are proceeding on schedule, and we hope to receive CD-2 approval sometime in spring 2013. When complete, the APS Upgrade will equip this vital facility for continued scientific leadership in the 21st century, providing the 5,000-plus members of our user community with greatly increased time, energy and spatial resolution. We also have successfully installed “Mira,” the new IBM Blue Gene/Q system at the Argonne Leadership Computing Facility. The world’s fourth-fastest supercomputer, Mira is now providing leading-edge computational power across all scientific disciplines. I am also pleased to report that Argonne’s new Energy Sciences Building is proceeding on schedule; we expect it to be finished and ready for occupancy by June 30, 2013. When complete, the ESB will be one of the most modern and most flexible energy labs in the world, creating a new home for researchers focused on a wide range of energy science challenges. Research is under way at the new multidisciplinary Institute for Molecular Engineering (IME), a joint program of the University of Chicago and Argonne. Over the past year, four new faculty members, including IME’s director, – all pre-eminent researchers who hold joint appointments at Argonne – have joined the IME. We look forward to working in collaboration with the IME to find new ways to address the interfaces between molecular-level science and powerful new technologies. In FY 2012, we continued support for the final year of the “Beyond Lithium-Ion” Director’s Grand Challenge LDRD project. That project enabled significant work on the performance of lithium-based energy storage systems, pointing the way to new high-energy-density lithium-air batteries. I believe this Grand Challenge contributed significantly to our successful bid to win designation of the Argonne-based Joint Center for Energy Storage Research (JCESR) as the DOE’s new Batteries and Energy Storage Hub. JCESR, which brings together a world-class “dream team” of national laboratories, universities and private sector partners, strongly benefited from LDRD program investments, both in FY2012 and in previous years. As we move forward in FY2013, the Director’s Grand Challenge is now focused on new ways to address the challenges of “big data” – the acquisition, storage, transfer, and analysis of both experimental and simulated data at scales approaching the limits of our current computational capacities. In managing Argonne’s LDRD program, we have adhered to the requirements of DOE Order 413.2b and associated guidelines. Our program management continually strives for increased efficiency. In addition to meeting all reporting requirements during FY 2012, our LDRD Program Office continues to implement intranet-based process enhancements to better serve all LDRD stakeholders, including our DOE Site Office colleagues. As the following individual project reports demonstrate, Argonne’s researchers are pursuing projects at the leading edge of science and engineering, and making significant contributions to the advancement of our laboratory’s major strategic initiatives. Evidence of the continuing strength of this program is found in the follow-on sponsorship won by many of these research projects, as well as in the numbers of publications, invited presentations, inventions, and new staff hires that are direct results of LDRD. LDRD enables exploration of new scientific directions and makes it possible to adapt quickly to a changing landscape with unexpected opportunities, while enhancing the capabilities of our researchers and our scientific facilities. For these reasons, LDRD remains an invaluable resource to address the future science and technology needs of DOE, and of our nation.

96 KNOWLEDGE MANAGEMENT AND PRESERVATION↗

Jupiter Laser Facility Annual Report, FY 2025

Dear JLF community, I cannot believe I am now entering my third year as JLF director — time definitely flies when you are having fun! FY25 was another pivotal year for the Jupiter Laser Facility, marked by both scientific achievement and growing visibility for our community. Building on the successful reopening and refurbishment of the facility, we continued to demonstrate how JLF drives innovation in high energy density and fusion energy science, laser technology, and workforce development. Across Janus, Titan, and COMET, users executed a diverse portfolio of experiments, from dynamic compression and opacity measurements to laser plasma interactions, laboratory astrophysics, and advanced diagnostics. These efforts are highlighted in this report, including the development of new probes that capture the time evolution of plasmas on a single shot, and diagnostics and platforms that are already impacting experiments at NIF and other large facilities. JLF continues to serve as both a testbed for new ideas and a bridge to larger scale campaigns. FY25 also showcased the broader role of JLF within the Laboratory and the national HED science ecosystem. The NIF JLF User Groups Meeting in February brought nearly 180 participants to Livermore and highlighted the scientific progress made during JLF’s first full year of renewed operations. JLF research and users were recognized with Director’s Institutional Awards and Early and Mid Career awards, underscoring the quality and impact of the work performed here. Our team also contributed prominently to national conversations about laser safety, plasma physics, and inertial fusion energy through invited talks, conferences, and professional society leadership. JLF’s integration with LaserNetUS deepened this year as well. We launched a new technical exchange program across LaserNetUS facilities and kicked it off with a JLF team visit to the BELLA Center at Lawrence Berkeley National Laboratory. These exchanges are strengthening operations, sharing best practices, and improving the user experience across the network. Filming for the LaserNetUS “Behind the Scenes” series and participation in the annual LaserNetUS meeting further increased the visibility of our facility and our users. At the same time, JLF continues to play a central role in ambitious new programs, such as the Big Aperture Thulium laser effort funded through one of the DOE Office of Science Microelectronics Science Research Centers, which will use JLF infrastructure to explore next generation high rep rate lasers for EUV and x-ray source development. A core part of our mission remains training the next generation of scientists. In FY25, we welcomed another cohort of summer students, who joined experimental teams on Titan and presented their research at LLNL’s student poster symposium and national inertial fusion energy meetings. JLF users and early career scientists showcased their work at conferences across the country, highlighting experiments performed at the facility. These hands on experiences, and the mentoring provided by our staff and user teams, are central to JLF’s identity as a true user facility. Finally, FY25 reinforced JLF’s role as a focal point for partnerships and outreach. We hosted visits from international collaborators, science leaders, and we shared the story of the facility through venues such as the Big Ideas Lab podcast. These interactions help connect our work to a broader scientific and policy audience and open new pathways for collaboration. As we look ahead, the combination of refurbished hardware, new capabilities like STILETTO and enhanced short pulse performance on Titan, strong partnerships across LLNL and LaserNetUS, and a growing user community positions JLF for an even more ambitious program in the coming years. I am deeply grateful to our technical and operations staff for their dedication, to our LLNL partners for their continued support, and to our users for bringing bold, creative ideas to the facility. I look forward to more experiments, capabilities, partnerships, and groundbreaking science in the years to come! With brightest regards, Félicie Albert, JLF Director.

70 PLASMA PHYSICS AND FUSION TECHNOLOGY↗

Motility of acoustically powered micro-swimmers in a liquid crystalline environment

Suspensions of microswimmers in liquid crystals demonstrate remarkably complex dynamics and serve as a model system for studying active nematics. So far, experimental realization of microswimmers suspended in liquid crystalline media has relied on biological microorganisms that impose strict limitations on the compatible media and makes it difficult to regulate activity. Here, we demonstrate that acoustically powered bubble microswimmers can efficiently self-propel in a lyotropic liquid crystal. The velocity of the swimmers is controlled by the amplitude of the acoustic field. Histograms of swimming directions with respect to the local nematic field reveal a bimodal distribution: the swimmers tend to either fully align with or swim perpendicular to the director field of the liquid crystal, occasionally switching between these two states. The bubble-induced streaming from a swimmer locally melts the liquid crystal and produces topological defects at the tail of the swimmer. Further, we show that the defect proliferation rate increases with the angle between the swimmer's velocity and the local orientation of the director field.

36 MATERIALS SCIENCE↗

RLUOB Celebration

Los Alamos National Laboratory's newest facility, the Radiological Laboratory Utility Office Building (RLUOB), is also its first to achieve both the Leadership in Energy and Environmental Design (LEED) status and LEED Gold certification from the U.S. Green Building Council (USGBC). From its robust design to its advanced scientific equipment, RLUOB is essential to the Laboratory's national security mission in support of the National Nuclear Security Administration's (NNSA) nuclear weapons program. At more than 200,000 square feet, this building is the only radiological facility within the Department of Energy to have attained LEED Gold, which contributes to NNSA's achievement towards the high performance sustainable building goals outlined in Executive Order 13514, Federal Leadership in Environmental, Energy, and Economic Performance. 'As we celebrate RLUOB being completed almost one year ahead of schedule and having achieved LEED certification at the Gold level, we approach our plutonium mission at Los Alamos and NNSA with a great sense of achievement,' said Don Cook, NNSA's deputy administrator for defense programs. 'RLUOB adds a major component to NNSA's plutonium support capability and RLUOB demonstrates our commitment in helping to deliver President Obama's nuclear security agenda which includes ensuring the safety, security and effectiveness of the nuclear deterrent without testing.' The facility contains laboratories for analytical chemistry and materials characterization of special nuclear material, along with space for offices, training and emergency operations. Its multi-functional purpose makes RLUOB a unique project for which LEED certification was sought. 'LEED certification was a huge goal and one we sought from the very beginning of this project,' said Laboratory Director Charlie McMillan. 'It's an important step forward, allowing us to advance national security science in modern, safer, more efficient infrastructure.' The Laboratory's project team and its contractor partners, especially in coordination with Jacobs Engineering, focused on green design and construction in LEED categories, such as sustainable sites, water efficiency, energy and atmosphere, materials and resources, indoor environmental quality and innovation in design. RLUOB's features include: (1) Building envelope design (orientation, materials and insulation) yielded a 20 percent improvement in energy performance; (2) Incorporation of building materials with 24 percent recycled content; (3) Diversion of 72 percent of construction-generated materials through reuse, recycle and salvage; (4) Roofing comprised of 93 percent highly-reflective materials to reduce heat island effects; (5) High efficiency, gas-fired hot water boilers, air-cooled chillers, thermal storage systems and variable frequency drives for compressors, fans and pumps; (6) Energy efficient lighting for interiors, exteriors, process glove boxes and fume hoods; (7) Water efficient fixtures resulting in 30 percent reduction in usage; (8) Low emission paints and carpeting for improved indoor air quality; (9) Landscaping that doesn't require permanent irrigation; (10) Enhanced building system commissioning; and (11) Comprehensive transportation alternatives, including public transportation, bicycle storage and changing rooms, and a refueling station for government vehicles using alternative fuels. 'RLUOB's LEED certification demonstrates tremendous leadership in green building,' says Rick Fedrizzi, president and CEO of USGBC. 'The urgency of our mission has challenged the industry to move faster and reach further than ever before, and RLUOB serves as a prime example of just how much we can accomplish.'

25 ENERGY STORAGE↗

NIF Operations Management Plan, August 2011

Lawrence Livermore National Laboratory’s (LLNL) National Ignition Facility (NIF) is a key component of the National Nuclear Security Administration’s (NNSA) Stockpile Stewardship Program, whose purpose is to maintain the safety, reliability, and effectiveness of our nation’s nuclear stockpile without underground nuclear testing. The NIF is crucial to the Stockpile Stewardship Program because it is the only facility that can create the conditions of extreme temperature and pressure—conditions that exist only in stars or in exploding nuclear weapons—that are relevant to understanding how our modern nuclear weapons operate. As such, the NIF’s primary mission is to attain fusion ignition in the laboratory. Fusion ignition not only supports Stockpile Stewardship needs, but also provides the basis for future decisions about fusion’s potential as a long-term energy source. Additionally, NIF provides scientists with access to high-energy-density regimes that can yield new insight and understanding in the areas of astrophysics, hydrodynamics, material properties, plasma physics, and radiative properties. The use of the NIF to support the Stockpile Stewardship Program and the advancement of basic high-energy-density science understanding is planned and managed through program-level execution plans and NIF directorate-level management teams. An example of a plan is the National Ignition Campaign Execution Plan. The NIF Operations Management Plan provides an overview of the NIF Operations organization and describes how the NIF is supported by the LLNL infrastructure and how it is safely and responsibly managed and operated. Detailed information on NIF management of the organization is found in a series of supporting plans, policies, and procedures. A list of related acronyms can be found in Appendix A of this document. The purpose of this document is to provide a roadmap of how the NIF Operations organization functions. It provides a guide to understanding the requirements, document flow down, organizational vision and mission, performance metrics, and interrelationship of the NIF Operations organization with other directorate and laboratory organizations. This document also provides a listing of roles and responsibilities, core processes, procedures, authority matrices, change control boards, and other information necessary for successfully functioning in the NIF Operations organization. This document, the NIF Shot Operations Plan, and the NIF Maintenance Plan together represent the primary documents satisfying our Conduct of Operations compliance requirement.

42 ENGINEERING↗

Toward a New Light: ALS Upgrade Project Moves Forward

This video highlights the next step toward realization of an upgrade at Berkeley Lab's scientific centerpiece, the Advanced Light Source. This 2-minute video provides a historical context of pioneering discoveries and innovations in accelerator science that have been a Berkeley Lab hallmark since its inception. The video also details the technology that will transform the ALS –producing beams of light 100 times brighter than today that also have a more ordered ("coherent") structure, like regularly spaced ripples in a pond – and the science that this upgrade will enable. The video features interviews with: Michael Witherell, Berkeley Lab Director David Robin, ALS Upgrade (ALS-U) Project Director Elke Arenholz, Senior Staff Scientist, ALS (Video Credit: Marilyn Chung/Berkeley Lab)

43 PARTICLE ACCELERATORS↗

Center Director's Discretionary Fund 2005 Annual Report

The FY 2005 CDDF projects were selected from the following spaceport and range technology and science areas: fluid system technologies; spaceport structures and materials; command, control, and monitoring technologies; and biological sciences (including support for environmental stewardship). The FY 2005 CDDF research projects involved development of the following: a) Capacitance-based moisture sensors to optimize plant growth in reduced gravity; b) Commodity-free calibration methods; c) Application of atmospheric plasma glow discharge to alter the surface properties of polymers for improved electrostatic dissipation characteristics; d) A wipe-on, wipe-off chemical process to remove lead oxides found in paint; e) A robust metabolite profiling platform for better understanding the "law" of biological regulation; f) An explanation of the excavation processes that occur when a jet of gas impinges on a bed of sand; g) "Smart coatings" to detect and control corrosion at an early stage to prevent further corrosion h) A model that can produce a reliable diagnosis of the quality of a software product; i) The formulation of advanced materials to meet system safety needs to minimize electrostatic charges, flammability, and radiation exposure; j) A lab-based instrument that uses the electro-optic Pockels effect to make static electric fields visible; k) A passive volatile organic compound (VOC) cartridge to filter, identify, and quantify VOCs flowing into or emanating from plant flight experiments.

Nurge, Mark↗