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At least 811 records · Page 45
All sourcesNASA NTRSDOE OSTI
DOE OSTI2022

Computational Study of Variable Fuel-Air Ratio and Hydrogen Doping in a Rotating Detonation Engine

Rotating detonation engines (RDEs) hold great promise as a technology for powering aviation engines. The pressure gain that results from continuously traversing detonation waves enables high theoretical performance compared to deflagration-based combustion. However, the harsh operating conditions inside an RDE restrict the availability of suitable experimental diagnostics to study these systems in detail and the range of spatial and temporal scales render numerical simulations of these systems difficult. In this study, we have combined adaptive mesh refinement and a robust shock-capturing approach to study RDE systems computationally using the compressible, reactive solver PeleC. Multi-species transport along with compressible Navier-Stokes equations are solved in the model along with finite-rate chemistry. Complex geometries are represented using an embedded boundary method with second-order spatial accuracy and the system is evolved in time using a second-order Runge-Kutta method. We present studies of a methane-air RDE system that is doped with varying levels of hydrogen. Our analysis focusses on how fuel mixture and doping levels effect the detonation flame structure and the generation of multiple wave modes.

ADVANCED PROPULSION SYSTEMS↗
DOE OSTI2015

Using multiple secondary fusion products to evaluate fuel ρR, electron temperature, and mix in deuterium-filled implosions at the NIF

In deuterium-filled inertial confinement fusion implosions, the secondary fusion processes D( 3 He,p) 4 He and D(T,n) 4 He occur, as the primary fusion products 3 He and T react in flight with thermal deuterons. In implosions with moderate fuel areal density (~ 5–100 mg/cm 2 ), the secondary D- 3 He reaction saturates, while the D-T reaction does not, and the combined information from these secondary products is used to constrain both the areal density and either the plasma electron temperature or changes in the composition due to mix of shell material into the fuel. The underlying theory of this technique is developed and applied to three classes of implosions on the National Ignition Facility: direct-drive exploding pushers, indirect-drive 1-shock and 2-shock implosions,and polar direct-drive implosions. In the 1- and 2-shock implosions, the electron temperature is inferred to be 0.65 x and 0.33 x the burn-averaged ion temperature, respectively. The inferred mixed mass in the polar direct-drive implosions is in agreement with measurements using alternative techniques.

42 ENGINEERING↗
DOE OSTI2015

MODELING SOLAR CORONAL BRIGHT-POINT OSCILLATIONS WITH MULTIPLE NANOFLARE HEATED LOOPS

Intensity oscillations of coronal bright points (BPs) have been studied for the past several years. It has been known for a while that these BPs are closed magnetic loop-like structures. However, the initiation of such intensity oscillations is still an enigma. There have been many suggestions to explain these oscillations, but so far modeling such BPs has not been explored. Using a multithreaded nanoflare heated loop model we study the behavior of such BPs in this work. We compute typical loop lengths of BPs using potential field-line extrapolation of available data, and set this as the length of our simulated loops. We produce intensity-like observables through forward modeling and analyze the intensity time series using wavelet analysis, as was done by previous observers. The result reveals similar intensity oscillation periods reported in past observations. It is suggested these oscillations are actually shock wave propagations along the loop. We also show that if one considers different background subtractions, one can extract adiabatic standing modes from the intensity time-series data as well, both from the observed and simulated data.

79 ASTRONOMY AND ASTROPHYSICS↗
DOE OSTI2018

New Neutron-capture Site in Massive Pop III and Pop II Stars as a Source for Heavy Elements in the Early Galaxy

We propose a new neutron-capture site in early metal-poor and metal-free stars of ~20–30 M ⊙ that results from proton ingestion in the He shell during late stages of the stars' lives. Most of the neutron capture occurs in the first lesssim106 s following proton ingestion when 13 C(α, n) 16 O produces neutron densities typical of the intermediate neutron-capture process. This phase may be followed by another lasting gsim10 7 s with 17 O(α, n) 20 Ne producing much lower neutron densities typical of the slow neutron-capture process. We explore the dependence of the proposed neutron-capture nucleosynthesis on the amount and time of proton ingestion, the initial metallicity, and the ensuing supernova shock. We obtain a range of heavy-element abundance patterns, including those attributed to the slow neutron-capture process or a combination of the slow and rapid neutron-capture processes. Our results can account for the observed ubiquity of heavy elements such as Sr and Ba in the early Galaxy and explain puzzling abundance patterns of these elements in at least some very metal-poor (VMP) stars, including those of the carbon-enhanced varieties. In the latter case, the explanation by the single site proposed here differs from the existing paradigm that attributes various classes of VMP stars to enrichment by multiple different sites.

79 ASTRONOMY AND ASTROPHYSICS↗
NASA NTRS2015

On-Orbit Quantitative Real-Time Gene Expression Analysis Using the Wetlab-2 System

NASA Ames Research Center's WetLab-2 Project enables on-orbit quantitative Reverse Transcriptase PCR (qRT-PCR) analysis without the need for sample return. The WetLab-2 system is capable of processing sample types ranging from microbial cultures to animal tissues dissected on-orbit. The project developed a RNA preparation module that can lyse cells and extract RNA of sufficient quality and quantity for use as templates in qRT-PCR reactions. Our protocol has the advantage of using non-toxic chemicals and does not require alcohols or other organics. The resulting RNA is dispensed into reaction tubes that contain all lyophilized reagents needed to perform qRT-PCR reactions. System operations require simple and limited crew actions including syringe pushes, valve turns and pipette dispenses. The project selected the Cepheid SmartCycler (TradeMark), a Commercial-Off-The-Shelf (COTS) qRT-PCR unit, because of its advantages including rugged modular design, low power consumption, rapid thermal ramp times and four-color multiplex detection. Single tube multiplex assays can be used to normalize for RNA concentration and integrity, and to study multiple genes of interest in each module. The WetLab-2 system can downlink data from the ISS to the ground after a completed run and uplink new thermal cycling programs. The ability to conduct qRT-PCR and generate results on-orbit is an important step towards utilizing the ISS as a National Laboratory facility. Specifically, the ability to get on-orbit data will provide investigators with the opportunity to adjust experimental parameters in real time without the need for sample return and re-flight. On orbit gene expression analysis can also eliminate the confounding effects on gene expression of reentry stresses and shock acting on live cells and organisms or the concern of RNA degradation of fixed samples and provide on-orbit gene expression benchmarking prior to sample return. Finally, the system can also be used for analysis of air, surface, water, and clinical samples to monitor environmental pathogens and crew health. The validation flight of the WetLab-2 system using E. coli bacteria and mouse liver launched on SpaceX-7 in June 2015 and will remain on the ISS National Laboratory.

ISS tools↗
NASA NTRS1991

Multipoint observations of planar interplanetary magnetic field structures

IMF data made on November 1, 1984, by three spatially well-separated spacecraft in the solar wind are presented. The IMF measured by each of the spacecraft is found to consist of a multiplicity of structures within which the magnetic field varies in parallel planes. The orientations of these planes at the three spacecraft locations are similar. The planes are inclined at a large angle to the ecliptic, and they lie almost perpendicular to the nominal Parker spiral direction in the ecliptic. Intercomparisons of the measurements at the various spacecraft show that the IMF features at one spacecraft are clearly reproduced at another, with time delays required for signal propagation. From these time delays and the mutual separations of the spacecraft, it is inferred that the structures are convecting with the ambient flow. Simultaneous observations made downstream of the bow shock in the magnetosheath reveal that the magnetosheath magnetic field, too, is planar.

Farrugia, C. J.↗
DOE OSTI2014

High-resolution three-dimensional simulations of core-collapse supernovae in multiple progenitors

Three-dimensional (3D) simulations of core-collapse supernovae (CCSNe) are granting new insight into the as-yet-uncertain mechanism that drives successful explosions. While there is still debate about whether explosions are obtained more easily in 3D than in 2D, it is undeniable that there exist qualitative and quantitative differences between the results of 3D and 2D simulations. We present an extensive set of high-resolution 1D, 2D, and 3D CCSN simulations with multispecies neutrino leakage carried out in two different progenitors. Our simulations confirm the results of Couch indicating that 2D explodes more readily than 3D. We argue that this is due to the inadequacies of 2D to accurately capture important aspects of the 3D dynamics. We find that without artificially enhancing the neutrino heating rate, we do not obtain explosions in 3D. We examine the development of neutrino-driven convection and the standing accretion shock instability (SASI) and find that, in separate regimes, either instability can dominate. We find evidence for growth of the SASI for both 15 M {sub ☉} and 27 M {sub ☉} progenitors; however, it is weaker in 3D exploding models. The growth rate of both instabilities is artificially enhanced along the symmetry axis in 2D as compared with our axis-free 3D Cartesian simulations. Our work highlights the growing consensus that CCSNe must be studied in 3D if we hope to solve the mystery of how the explosions are powered.

79 ASTRONOMY AND ASTROPHYSICS↗
DOE OSTI2017

ALMA Images of the Orion Hot Core at 349 GHz

We present ALMA images of the dust and molecular line emission in the Orion Hot Core at 349 GHz. At 0.″2 angular resolution the images reveal multiple clumps in an arc ∼1″ east of Orion Source I, the protostar at the center of the Kleinmann–Low Nebula, and another chain of peaks from IRc7 toward the southwest. The molecular line images show narrow filamentary structures at velocities >10 km s{sup −1} away from the heavily resolved ambient cloud velocity ∼5 km s{sup −1}. Many of these filaments trace the SiO outflow from Source I, and lie along the edges of the dust emission. Molecular line emission at excitation temperatures 300–2000 K, and velocities >10 km s{sup −1} from the ambient cloud, suggest that the Hot Core may be heated in shocks by the outflow from Source I or from the Becklin–Neugebauer (BN)/SrcI explosion. The spectral line observations also reveal a remarkable molecular ring, ∼2″ south of SrcI, with a diameter ∼600 au. The ring is seen in high-excitation transitions of HC{sub 3}N, HCN v 2 = 1, and SO{sub 2}. An impact of ejecta from the BN/SrcI explosion with a dense dust clump could result in the observed ring of shocked material.

79 ASTRONOMY AND ASTROPHYSICS↗
NASA NTRS1990

Some Aspects of Essentially Nonoscillatory (ENO) Formulations for the Euler Equations, Part 3

An essentially nonoscillatory (ENO) formulation is described for hyperbolic systems of conservation laws. ENO approaches are based on smart interpolation to avoid spurious numerical oscillations. ENO schemes are a superset of Total Variation Diminishing (TVD) schemes. In the recent past, TVD formulations were used to construct shock capturing finite difference methods. At extremum points of the solution, TVD schemes automatically reduce to being first-order accurate discretizations locally, while away from extrema they can be constructed to be of higher order accuracy. The new framework helps construct essentially non-oscillatory finite difference methods without recourse to local reductions of accuracy to first order. Thus arbitrarily high orders of accuracy can be obtained. The basic general ideas of the new approach can be specialized in several ways and one specific implementation is described based on: (1) the integral form of the conservation laws; (2) reconstruction based on the primitive functions; (3) extension to multiple dimensions in a tensor product fashion; and (4) Runge-Kutta time integration. The resulting method is fourth-order accurate in time and space and is applicable to uniform Cartesian grids. The construction of such schemes for scalar equations and systems in one and two space dimensions is described along with several examples which illustrate interesting aspects of the new approach.

Chakravarthy, Sukumar R.↗
DOE OSTI2016

Ocular toxicity of AUY922 in pigmented and albino rats

AUY922, a heat shock protein 90 inhibitor is associated with ocular adverse events (AEs). To provide a better understanding of ocular AEs in patients, 4 investigative studies were performed in a step-wise approach to assess retinal structure and function in pigmented (Brown Norway) and albino (Wistar) rats. In rats administered 30 mg/kg of AUY922, the AUC{sub 0–24} {sub h} and C{sub max} are comparable to that in patients at 70 mg/m{sup 2}. AUY922 at ≥ 30 mg/kg was poorly tolerated by rats with morbidity or mortality generally after the third weekly treatment. Electroretinography (ERG) changes were observed at doses ≥ 30 mg/kg. The ERG changes were dose dependent, consistent with an effect on the photoreceptors, and fully reversible. The ERG effects could not be minimized by decreasing the C{sub max} while maintaining AUC. Histopathological changes were seen mainly when rats were administered AUY922 at 100 mg/kg. The 2-hour infusion of AUY922 at 100 mg/kg caused disorganization of the outer segment photoreceptor morphology in male Brown Norway rats; the severity of the disorganization increased with the number of administrations, but was reversible during a 4-week posttreatment period. There was no major difference in ocular response between Brown Norway and Wistar rats. No changes in serum iron levels, and no changes in rhodopsin, PDE6α, β-transducin concentrations, or retinal pigment epithelium-specific protein RPE65 expression were observed after single and multiple infusions of AUY922 at 100 mg/kg compared to vehicle-treated controls. AUY922 retinal toxicity in rats recapitulates and further characterizes that reported in patients and is shown to be reversible, while a precise molecular mechanism for the effect was not determined. - Highlights: • Ocular toxicity of AUY922 was assessed in Brown Norway and Wistar rats. • AUY922 at ≥ 30 mg/kg was generally not well tolerated by rats. • Electroretinography (ERG) changes were observed at doses ≥ 30 mg/kg. • ERG changes at doses ≥ 30 mg/kg were dose-dependent, and fully reversible.

54 ENVIRONMENTAL SCIENCES↗
DOE OSTI2017

Second Generation Grp94-Selective Inhibitors Provide Opportunities for the Inhibition of Metastatic Cancer

Glucose regulated protein 94 (Grp94) is the endoplasmic reticulum (ER) resident isoform of the 90 kDa heat shock protein (Hsp90) family and its inhibition represents a promising therapeutic target for the treatment of many diseases. Modification of the first generation cis-amide bioisostere imidazole to alter the angle between the resorcinol ring and the benzyl side chain via cis-amide replacements produced compounds with improved Grp94 affinity and selectivity. Structure–activity relationship studies led to the discovery of compound 30, which exhibits 540 nm affinity and 73-fold selectivity towards Grp94. Grp94 is responsible for the maturation and trafficking of proteins associated with cell signaling and motility, including select integrins. The Grp94-selective inhibitor 30 was shown to exhibit potent anti-migratory effects against multiple aggressive and metastatic cancers.

59 BASIC BIOLOGICAL SCIENCES↗
DOE OSTI2019

Particle heating and energy partition in low- β guide field reconnection with kinetic Riemann simulations

Kinetic Riemann simulations have been completed to investigate particle heating during guide field reconnection in the low-β environment of the inner heliosphere and the solar corona. The reconnection exhaust is bounded by two rotational discontinuities (RDs), and two slow shocks (SSs) form within the exhaust as in magnetohydrodynamic (MHD) models. At the RDs, ions are accelerated by the magnetic field tension to drive the reconnection outflow as well as flows in the out-of-plane direction. The out-of-plane flows stream toward the midplane and meet to drive the SSs. The SSs differ greatly from those in the MHD model. The turbulence at the shock fronts and both upstream and downstream is weak, and so the shocks are laminar and produce little dissipation. Downstream of the SSs, the counterstreaming ion beams lead to higher density, which leads to a positive potential between the SSs which acts to confine the downstream electrons to maintain charge neutrality. The potential accelerates electrons from upstream of the SSs to the downstream region and traps a small fraction but only modestly increases the downstream electron temperature above the upstream value. In the low-β limit, the released magnetic energy is split between bulk flow and ion heating with little energy going to electrons. That the model produces neither strong electron heating nor an energetic electron component implicates that other mechanisms, such as multiple x-line reconnection, are required to explain energetic electron production in large flares. The model can be tested with the expected data from the Parker Solar Probe.

70 PLASMA PHYSICS AND FUSION TECHNOLOGY↗
DOE OSTI2021

HED Hydrodynamics in the Common Modeling Framework

Within the Common Modeling Framework (CMF), the HED Hydrodynamics Project has implemented a common methodology, or "Authority", for modeling high energy density (HED) experiments by extending development of the Eulerian Applications Project code Authority, "EAPA," to include relevant physics models, customization tools and templates, and in situ and post-processing capabilities. Additionally, several models for small-scale HED experiments were successfully added to the CMF and simulations reproduce the results of preexisting, benchmarked input decks. We expect use of the CMF to improve our effectiveness in developing predictive capabilities for experiments ranging from small-scale planar single-interface, single-shock to multi-interface, multi-shock configurations and up through multi-shell inertial confinement fusion (ICF) implosions. Additionally, this will strengthen our ability to design future targeted experiments. Using the CMF infrastructure and Authorities for HED modeling has three key impacts. First, it enables a version-controlled, pedigreed and archived base model for each experiment with tools that allow easy setup, execution and analysis of simulations to assess and/or expose sensitivities to various parameters. Second, having a common base set of inputs and physics definitions helps identify systematic differences between models in the codes and experimental data to support code validation, and build confidence in our predictive capabilities. Finally, designed to work in concert with multiple programs and projects including PEM, IC, OES, V&V and DSW, the CMF supports improved collaboration and integration through shared model definitions, data, simulations and results, enhancing the workflow required to underwrite the knowledge base and capabilities ultimately required for stockpile stewardship

72 PHYSICS OF ELEMENTARY PARTICLES AND FIELDS↗
NASA NTRS1987

Plasma contactors for use with electrodynamic tethers for power generation

Plasma contactors have been proposed as a means of making good electrical contact between biased surfaces such as found at the ends of an electrodynamic tether and the space environment. A plasma contactor is a plasma source which emits a plasma cloud which facilitates the electrical connection. The physics of this plasma cloud is investigated for contactors used as electron collectors and it is shown that contactor clouds in space will consist of a spherical core possibly containing a shock wave. Outside of the core the cloud will expand anisotropically across the magnetic field leading to a turbulent cigar shape structure along the field. This outer region is itself divided into two regions by the ion response to the electric field. A two dimensional theory of the motion of the cloud across the magnetic field is developed. The current voltage characteristic of an Argon plasma contactor cloud is estimated for several ion currents in the range of 1-100 Amperes. It is shown that small ion current contactors are more efficient than large ion current contactors. This suggests that if a plasma contactor is used on an electrodynamic tether, then a multiple tether array will be more efficient than a single tether.

Hastings, D. E.↗
NASA NTRS1993

Dynamic-overlapped-grid simulation of aerodynamically determined relative motion

Currently, there is a need to develop a means of analyzing and studying unsteady flowfields which involve multiple component configurations with at least one of the components in relative motion with respect to the others. Two of the important phenomena that such analyses can help to understand are the unsteady aerodynamic interference and the boundary-induced component of the flowfield. With this motivation, a computational method is developed which couples the governing equations of the unsteady flowfield and the rigid-body dynamics in six degrees-of-freedom. These equations are solved on composite meshes of overlapped subdomain grids which can move with respect to each other. Initially, several measures that reduce the numerical error are studied and compared with the exact solution of a moving normal shock in a tube. It is concluded that a second-order accurate method, for spatial and temporal discretizations as well as for the moving subdomain interpolations, is needed as a minimum measure. Furthermore, the CFL numbers should be restricted to unity. Then, the method is used to simulate the flowfield history and predict the aerodynamically determined trajectory of a store dropped from its initial position under a wing.

Yen, Guan-Wei↗
DOE OSTI2015

Toward a better understanding of the GRB phenomenon: A new model for GRB PROMPT emission and its effects on the new L{sub i}{sup NT}– E{sub peak,i}{sup rest,NT} relation

Gamma-ray burst (GRB) prompt emission spectra in the keV–MeV energy range are usually considered to be adequately fitted with the empirical Band function. Recent observations with the Fermi Gamma-ray Space Telescope (Fermi) revealed deviations from the Band function, sometimes in the form of an additional blackbody (BB) component, while on other occasions in the form of an additional power law (PL) component extending to high energies. In this article we investigate the possibility that the three components may be present simultaneously in the prompt emission spectra of two very bright GRBs (080916C and 090926A) observed with Fermi, and how the three components may affect the overall shape of the spectra. While the two GRBs are very different when fitted to a single Band function, they look like “twins” in the three-component scenario. Through fine-time spectroscopy down to the 100 ms timescale, we follow the evolution of the various components. We succeed in reducing the number of free parameters in the three-component model, which results in a new semi-empirical model—but with physical motivations—to be competitive with the Band function in terms of number of degrees of freedom. From this analysis using multiple components, the Band function is globally the most intense component, although the additional PL can overpower the others in sharp time structures. The Band function and the BB component are the most intense at early times and globally fade across the burst duration. The additional PL is the most intense component at late time and may be correlated with the extended high-energy emission observed thousands of seconds after the burst with Fermi/Large Area Telescope. Unexpectedly, this analysis also shows that the additional PL may be present from the very beginning of the burst, where it may even overpower the other components at low energy. We investigate the effect of the three components on the new time-resolved luminosity–hardness relation in both the observer and rest frames and show that a strong correlation exists between the flux of the non-thermal Band function and its E{sub peak} only when the three components are fitted simultaneously to the data (i.e., F{sub i}{sup NT}–E{sub peak,i}{sup NT} relation). In addition, this result points toward a universal relation between those two quantities when transposed to the central engine rest frame for all GRBs (i.e., L{sub i}{sup NT}–E{sub peak,i}{sup rest,NT} relation). We discuss a possible theoretical interpretation of the three spectral components within this new empirical model. We suggest that (i) the BB component may be interpreted as the photosphere emission of a magnetized relativistic outflow, (ii) the Band component has synchrotron radiation in an optically thin region above the photosphere, either from internal shocks or magnetic field dissipation, and (iii) the extra PL component extending to high energies likely has an inverse Compton origin of some sort, even though its extension to a much lower energy remains a mystery.

79 ASTRONOMY AND ASTROPHYSICS↗
DOE OSTI2017

The Solar Energetic Particle Event of 2010 August 14: Connectivity with the Solar Source Inferred from Multiple Spacecraft Observations and Modeling

We analyze one of the first solar energetic particle (SEP) events of solar cycle 24 observed at widely separated spacecraft in order to assess the reliability of models currently used to determine the connectivity between the sources of SEPs at the Sun and spacecraft in the inner heliosphere. This SEP event was observed on 2010 August 14 by near-Earth spacecraft, STEREO-A (∼80° west of Earth) and STEREO-B (∼72° east of Earth). In contrast to near-Earth spacecraft, the footpoints of the nominal magnetic field lines connecting STEREO-A and STEREO-B with the Sun were separated from the region where the parent fast halo coronal mass ejection (CME) originated by ∼88° and ∼47° in longitude, respectively. We discuss the properties of the phenomena associated with this solar eruption. Extreme ultraviolet and white-light images are used to specify the extent of the associated CME-driven coronal shock. We then assess whether the SEPs observed at the three heliospheric locations were accelerated by this shock or whether transport mechanisms in the corona and/or interplanetary space provide an alternative explanation for the arrival of particles at the poorly connected spacecraft. A possible scenario consistent with the observations indicates that the observation of SEPs at STEREO-B and near Earth resulted from particle injection by the CME shock onto the field lines connecting to these spacecraft, whereas SEPs reached STEREO-A mostly via cross-field diffusive transport processes. The successes, limitations, and uncertainties of the methods used to resolve the connection between the acceleration sites of SEPs and the spacecraft are evaluated.

79 ASTRONOMY AND ASTROPHYSICS↗
DOE OSTI2015

CORONAL RAIN IN MAGNETIC ARCADES: REBOUND SHOCKS, LIMIT CYCLES, AND SHEAR FLOWS

We extend our earlier multidimensional, magnetohydrodynamic simulations of coronal rain occurring in magnetic arcades with higher resolution, grid-adaptive computations covering a much longer (>6 hr) time span. We quantify how blob-like condensations forming in situ grow along and across field lines and show that rain showers can occur in limit cycles, here demonstrated for the first time in 2.5D setups. We discuss dynamical, multi-dimensional aspects of the rebound shocks generated by the siphon inflows and quantify the thermodynamics of a prominence–corona transition-region-like structure surrounding the blobs. We point out the correlation between condensation rates and the cross-sectional size of loop systems where catastrophic cooling takes place. We also study the variations of the typical number density, kinetic energy, and temperature while blobs descend, impact, and sink into the transition region. In addition, we explain the mechanisms leading to concurrent upflows while the blobs descend. As a result, there are plenty of shear flows generated with relative velocity difference around 80 km s{sup −1} in our simulations. These shear flows are siphon flows set up by multiple blob dynamics and they in turn affect the deformation of the falling blobs. In particular, we show how shear flows can break apart blobs into smaller fragments, within minutes.

79 ASTRONOMY AND ASTROPHYSICS↗