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At least 811 records · Page 45

All sources NASA NTRS DOE OSTI

DOE OSTI2023

The Ontology of Biological Attributes (OBA)—computational traits for the life sciences

Abstract Existing phenotype ontologies were originally developed to represent phenotypes that manifest as a character state in relation to a wild-type or other reference. However, these do not include the phenotypic trait or attribute categories required for the annotation of genome-wide association studies (GWAS), Quantitative Trait Loci (QTL) mappings or any population-focussed measurable trait data. The integration of trait and biological attribute information with an ever increasing body of chemical, environmental and biological data greatly facilitates computational analyses and it is also highly relevant to biomedical and clinical applications. The Ontology of Biological Attributes (OBA) is a formalised, species-independent collection of interoperable phenotypic trait categories that is intended to fulfil a data integration role. OBA is a standardised representational framework for observable attributes that are characteristics of biological entities, organisms, or parts of organisms. OBA has a modular design which provides several benefits for users and data integrators, including an automated and meaningful classification of trait terms computed on the basis of logical inferences drawn from domain-specific ontologies for cells, anatomical and other relevant entities. The logical axioms in OBA also provide a previously missing bridge that can computationally link Mendelian phenotypes with GWAS and quantitative traits. The term components in OBA provide semantic links and enable knowledge and data integration across specialised research community boundaries, thereby breaking silos.

59 BASIC BIOLOGICAL SCIENCES↗

DOE OSTI2022

A Framework to Integrate Human Reliability Data Obtained from Different Sources Based on the Complexity Scores of Proceduralized Tasks

For many decades, PSA (Probabilistic Safety Assessment) or PRA (Probabilistic Risk Assessment) techniques have been used to enhance the operational safety of nuclear power plants (NPPs) based on the consideration of potential hazards that could result in an unexpected consequence. As human error is one of the potential hazards, diverse human reliability analysis (HRA) methods have been proposed to provide a systematic way to estimate the likelihood of human errors (i.e., human error probability, HEP) in specific task contexts. Accordingly, it is evident that the quality of HRA results strongly depends on the credibility of HEP estimations. This implies that, in terms of enhancing this credibility, the collection of raw information (HRA data) that is helpful for understating when and why human errors occur is a crucial issue. In order to address this issue, in this study, the feasibility of a framework to integrate HRA data obtained from different sources is investigated based on the complexity of proceduralized tasks.

99 GENERAL AND MISCELLANEOUS↗

DOE OSTI2023

Integrated Large-Scale Data Management Platform for Photovoltaic Power Conversion Equipment (PCE) Reliability Data

To meet the demand for accuracy and real-time capability of PV system degradation evaluation, massive volume data is needed to run high-fidelity and high-efficiency simulations and perform advanced data analysis. However, PV farm operators have a series of difficulties with PV inverter data, such as data collection from multiple channels, massive data storage, data management and massive data analysis. To address these challenges, we developed an integrated data management platform capable of data acquisition, processing, storage, query, and performing big data analysis utilizing AI algorithms. The platform can also achieve data correctness verification and provide an effective distributed data management solution to retrieve massive data and establish a connection to distributed computational frameworks.

data management platform↗

NASA NTRS1987

A structure-based model of semantic integrity constraints for relational data bases

Data base management systems (DBMSs) are in widespread use because of the ease and flexibility with which users access large volumes of data. Ensuring data accuracy through integrity constraints is a central aspect of DBMS use. However, many DBMSs still lack adequate integrity support. In additon, a comprehensive theoretical basis for such support the role of a constraint classification system - has yet to be developed. This paper presents a formalism that classifies semantic integrity constraints based on the structure of the relational model. Integrity constraints are characterized by the portion of the data base structure they access, whether one or more relations, attributes, or tuples. Thus, the model is completely general, allowing the arbitrary specification of any constraint. Examples of each type of constraint are illustrated using a small engineering data base, and various implementation issues are discussed.

Rasdorf, William J.↗

DOE OSTI2023

Integrated Large-Scale Data Management Platform for Photovoltaic Power Conversion Equipment (PCE) Reliability Data: Preprint

data management↗

NASA NTRS1975

Hypersonic research engine project. Phase 2: Aerothermodynamic integration model development, data item no. 55-4-21

The design and development of the Aerothermodynamic Integration Model (AIM) of the Hypersonic Research Engine (HRE) is described. The feasibility of integrating the various analytical and experimental data available for the design of the hypersonic ramjet engine was verified and the operational characteristic and the overall performance of the selected design was determined. The HRE-AIM was designed for operation at speeds of Mach 3 through Mach 8.

Jilly, L. F.↗

NASA NTRS1975

Hypersonic research engine project. Phase 2: Aerothermodynamic Integration Model (AIM) data reduction computer program, data item no. 54.16

The data reduction program used to analyze the performance of the Aerothermodynamic Integration Model is described. Routines to acquire, calibrate, and interpolate the test data, to calculate the axial components of the pressure area integrals and the skin function coefficients, and to report the raw data in engineering units are included along with routines to calculate flow conditions in the wind tunnel, inlet, combustor, and nozzle, and the overall engine performance. Various subroutines were modified and used to obtain species concentrations and transport properties in chemical equilibrium at each of the internal and external engine stations. It is recommended that future test plans include the configuration, calibration, and channel assignment data on a magnetic tape generated at the test site immediately before or after a test, and that the data reduction program be designed to operate in a batch environment.

Gaede, A. E.↗

NASA NTRS1999

Next Generation Space Telescope Integrated Science Module Data System

The Data system for the Next Generation Space Telescope (NGST) Integrated Science Module (ISIM) is the primary data interface between the spacecraft, telescope, and science instrument systems. This poster includes block diagrams of the ISIM data system and its components derived during the pre-phase A Yardstick feasibility study. The poster details the hardware and software components used to acquire and process science data for the Yardstick instrument compliment, and depicts the baseline external interfaces to science instruments and other systems. This baseline data system is a fully redundant, high performance computing system. Each redundant computer contains three 150 MHz power PC processors. All processors execute a commercially available real time multi-tasking operating system supporting, preemptive multi-tasking, file management and network interfaces. These six processors in the system are networked together. The spacecraft interface baseline is an extension of the network, which links the six processors. The final selection for Processor busses, processor chips, network interfaces, and high-speed data interfaces will be made during mid 2002.

Schnurr, Richard G.↗

NASA NTRS1985

Performance analysis of a fault inferring nonlinear detection system algorithm with integrated avionics flight data

This paper presents the performance analysis results of a fault inferring nonlinear detection system (FINDS) using integrated avionics sensor flight data for the NASA ATOPS B-737 aircraft in a Microwave Landing System (MLS) environment. First, an overview of the FINDS algorithm structure is given. Then, aircraft state estimate time histories and statistics for the flight data sensors are discussed. This is followed by an explanation of modifications made to the detection and decision functions in FINDS to improve false alarm and failure detection performance. Next, the failure detection and false alarm performance of the FINDS algorithm are analyzed by injecting bias failures into fourteen sensor outputs over six repetitive runs of the five minutes of flight data. Results indicate that the detection speed, failure level estimation, and false alarm performance show a marked improvement over the previously reported simulation runs. In agreement with earlier results, detection speed is faster for filter measurement sensors such as MLS than for filter input sensors such as flight control accelerometers. Finally, the progress in modifications of the FINDS algorithm design to accommodate flight computer constraints is discussed.

Caglayan, A. K.↗

NASA NTRS1984

60-GHz integrated-circuit high data rate quadriphase shift keying exciter and modulator

An integrated-circuit quadriphase shift keying (QPSK) exciter and modulator have demonstrated excellent performance directly modulating a carrier frequency of 60 GHz with an output phase error of less than 3 degrees and maximum amplitude error of 0.5 dB. The circuit consists of a 60-GHz Gunn VCO phase-locked to a low-frequency reference source, a 4th subharmonic mixer, and a QPSK modlator packaged into a small volume of 1.8 x 2.5 x 0.35 in. The use of microstrip has the advantages of small size, light-weight, and low-cost fabrication. The unit has the potential for multigigabit data rate applications.

Grote, A.↗

NASA NTRS2016

Integrating Large Scale Data Sets to Develop Predictive Hypotheses of Low-Dose Radiation-Induced Health Effects

Over one hundred years of radiation biology research has revealed much about the DNA damages induced by the deposition of energy from exposure to ionizing radiation and the subsequent cellular responses. However, there are still significant gaps in our understanding of how these might lead to detrimental health effects, particularly at low doses (100 mGy (milligray)). Recent advances in high throughput omics technologies enable interrogation of induced radiation effects at the genomic, proteomic and metabolomic levels. These include changes in gene expression, protein modifications, e.g., phosphorylation, acetylation, and methylation, and metabolic changes. We will discuss the integration of data obtained from multiple omics platforms to understand radiation dose, and dose rate effects in a complex human tissue model as a function of time. We will use as an example our results on the low dose responses in a 3D human skin model.

ionizing radiation↗

DOE OSTI2021

Informing nuclear physics via machine learning methods with differential and integral experiments

Information from differential nuclear-physics experiments and theory is often too uncertain to accurately define nuclear-physics observables such as cross sections or energy spectra. Integral experimental data, representing the applications of these observables, are often more precise but depend simultaneously on too many of them to unambiguously identify issues in the observable with human expert analysis alone. Here, we explore how we can leverage physics knowledge gained from differential experimental data, nuclear theory, integral experiments, and neutron-transport calculations to better understand nuclear-physics observables in the context of the application area represented by integral experiments. We support this task with machine-learning methods to discern trends in a large amount of convoluted data. Differential and integral information was used in an analysis augmented by the random forest and the Shapley additive explanations metric. We chose as an application area one that is represented by criticality measurements and pulsed-sphere neutron-leakage spectra. We show one representative example ( 241 Pu fission observables) where the combination of differential and integral information allowed to resolve issues in data representing these observables. As a starting point, the machine learning (ML) algorithms highlighted several observables as leading potentially to bias in simulating integral experiments. Differential information, paired with sensitivity to integral quantities, allowed us then to pinpoint one specific observable ( 241 Pu fission cross section) as the main driver of bias. The comparison to integral experiments, on the other hand, allowed us to indicate a likely reliable experiment among several discrepant ones for this observables. In other cases (e.g., 239 Pu observables), we were not able to resolve the confounding introduced by integral experiments but instead highlighted the need for targeted new experiments and theory developments to better constrain the nuclear-physics space for the application area represented by integral experiments. We were able to combine information from differential experimental data, nuclear-physics theory, integral experiments, and neutron-transport simulations of the latter experiments with the help of the random forest algorithm and expert judgment. This combination of knowledge allows to improve our description of nuclear-physics observables as applied to a particular application area.

73 NUCLEAR PHYSICS AND RADIATION PHYSICS↗

DOE OSTI2024

Data for "TRANSP integrated modeling code for interpretive and predictive analysis of tokamak plasmas"

Data for figures 6 and 8 describing shine-through power computed in NUBEAM and effective diffusivities in the USER model

experimental data analysis↗

DOE OSTI2026

Integration of GOES Data for Solar Resource Assessment of the Contiguous United States

The National Solar Radiation Database (NSRDB), produced by the National Laboratory of the Rockies (NLR), provides high-resolution solar resource data for the contiguous United States (CONUS) using Geostationary Operational Environmental Satellite (GOES) East and West observations. This study evaluates the integration of multi-satellite data within the GOES-East/West overlap regions, where conventional longitude-based selection methods often produce an artificial boundary seam. Our results demonstrate that an advanced blending algorithm, which incorporates sun-satellite scattering angles and satellite viewing zenith angles, improves NSRDB accuracy and creates a spatially continuous dataset. Validation against ground-based irradiance measurements reveals reductions in both percentage error (PE) and normalized Root Mean Square Error (nRMSE), particularly in the central United States. The dynamical integration of multi-satellite data provides a robust foundation for more precise modeling of solar resource and improved spatiotemporal analysis of solar ramp across the CONUS.

14 SOLAR ENERGY↗

NASA NTRS2018

Steps Toward Improved Integration, Search, and Analysis of Heterogeneous Data in the Astrobiology Habitable Environments Database

The Astrobiology Habitable Environments Database (AHED) is a new data system being developed as a long-term, open-access repository for astrobiology data. AHED is intended to store user-contributed results from NASA or externally-funded research in astrobiology, and to encourage sharing and synergy within the astrobiology community. However, the interdisciplinary nature of astrobiology presents some specific challenges to data management, integration, and analysis within AHED. In some disciplines (e.g., genomics), open databases thrive because the contributed products are fairly uniform and standardized (e.g., sequence data). In astrobiology, each investigation produces a unique set of data products; this makes it difficult to search across different datasets to find similar data, or to combine results from separate investigations. With AHED, we are taking steps to ensure there is adequate metadata - both at the dataset and record levels - to facilitate search, integration, and analysis. At the dataset level, we are developing a new metadata standard for describing astrobiology datasets, with detailed information about content, funding source, and scientific relevance, along with a set of topical keywords for characterizing datasets. At the record level, we are encouraging users to provide more structured content and finer-grained metadata. In many user-contributed science data repositories, few restrictions are placed on the uploaded data format, and minimal or no record-level metadata is required; thus users are unburdened when it comes to data preparation. The tradeoff is that deep integration and search across datasets is almost impossible without standardized structures and metadata. Although AHED users are free to upload minimally-described datasets, they will be encouraged to use database authoring tools (supplied by the underlying platform - Open Data Repository's Data Publisher) plus a set of customizable astrobiology-specific templates to help structure their data and provide standardized metadata. In reward for their extra effort, AHED will be able to deliver enhanced search, discovery, and analysis capabilities.

astrobiology↗

DOE OSTI2021

Time-Lapse Integration at FWU: Fluids, Rock Physics, Numerical Model Integration, and Field Data Comparison

We present the current status of time-lapse seismic integration at the Farnsworth (FWU) CO2 WAG (water-alternating-gas) EOR (Enhanced Oil Recovery) project at Ochiltree County, northwest Texas. As a potential carbon sequestration mechanism, CO2 WAG projects will be subject to some degree of monitoring and verification, either as a regulatory requirement or to qualify for economic incentives. In order to evaluate the viability of time-lapse seismic as a monitoring method the Southwest Partnership (SWP) has conducted time-lapse seismic monitoring at FWU using the 3D Vertical Seismic Profiling (VSP) method. The efficacy of seismic time-lapse depends on a number of key factors, which vary widely from one application to another. Most important among these are the thermophysical properties of the original fluid in place and the displacing fluid, followed by the petrophysical properties of the rock matrix, which together determine the effective elastic properties of the rock fluid system. We present systematic analysis of fluid thermodynamics and resulting thermophysical properties, petrophysics and rock frame elastic properties, and elastic property modeling through fluid substitution using data collected at FWU. These analyses will be framed in realistic scenarios presented by the FWU CO2 WAG development. The resulting fluid/rock physics models will be applied to output from the calibrated FWU compositional reservoir simulation model to forward model the time-lapse seismic response. Modeled results are compared with field time-lapse seismic measurements and strategies for numerical model feedback/update are discussed. While mechanical effects are neglected in the work presented here, complementary parallel studies are underway in which laboratory measurements are introduced to introduce stress dependence of matrix elastic moduli.

4D↗

NASA NTRS1993

Achieving high data reduction with integral cubic B-splines

During geometry processing, tangent directions at the data points are frequently readily available from the computation process that generates the points. It is desirable to utilize this information to improve the accuracy of curve fitting and to improve data reduction. This paper presents a curve fitting method which utilizes both position and tangent direction data. This method produces G(exp 1) non-rational B-spline curves. From the examples, the method demonstrates very good data reduction rates while maintaining high accuracy in both position and tangent direction.

Chou, Jin J.↗

DOE OSTI2022

Summary of NDC Capacity Building Workshop and Regional Seismic Travel Time (RSTT) in combination with Data Sharing and Integration Training

The NNSA Seismic Cooperation Program (SCP) sponsored Stephen Myers (LLNL), Michael Begnaud (LANL), Brian Young (SNL) and Istvan Bondar (Research Center for Astronomy and Earth Sciences, Hungary) to serve as a presenters/trainers at the “NDC Capacity Building Workshop and Regional Seismic Travel Time (RSTT) in combination with Data Sharing and Integration Training” September 4-8 2022 in Muscat, Oman (See Appendix A for the agenda). The workshop and training (workshop from here forward) was organized by the Comprehensive Nuclear-Test-Ban Treaty Organization (CTBTO) Provisional Technical Secretariat (PTS). The first half of the week was devoted to NDC workshop activities, and the second half was devoted to RSTT training. Fifty-five participants from 27 countries and the CTBTO-PTS attended the 5-day workshop (See Appendix B for list of participants and countries of origin). Presentations from the PTS described the International Monitoring System (IMS), International Data Centre (IDC) products, and metrics of regional data utilization. Contributed presentations from each country’s scientists included descriptions of regional and national networks, methods of data analysis, and needs for material and technical assistance. Training included an overview of the RSTT method and instruction on how to locate seismic events with the iLoc program, which utilizes RSTT travel times to reduce bias in event location estimates. Methods of seismic tomography and the need for a high-quality tomographic set, including seismological “ground truth”, were emphasized. Seismological “ground truth” or “GT” is a term that has come to mean both events with known location and events with well-characterized locations that are estimated using seismological data, typically with epicenter accuracy of 5 km or better. Notably, the instructional platform has migrated from UNIX shell scripts to Jupyter Notebooks. Jupyter Notebooks have the advantage being more visually intuitive, including display of graphics within the notebook. Each notebook includes every processing step that participants need to reproduce the entire exercise.

58 GEOSCIENCES↗