Synthesis and antiproliferative activity of hindered, chiral 1,2-diaminodiamantane platinum( ii ) complexes
Platinum-based antineoplastic agents play a major role in the treatment of numerous types of cancer.
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Platinum-based antineoplastic agents play a major role in the treatment of numerous types of cancer.
The development of polar MHSs with competitive chiroptical and magnetic properties, featuring record air stability of over a year.
Immunogenicity and endogenous biotin interference limit streptavidin's therapeutic/diagnostic potential. Synthesized l - and d -streptavidin demonstrate high stereospecificity, supporting the utility of a mirror-image biotin/streptavidin system.
The ab initio symmetry-adapted no-core shell model naturally describes nuclear deformation and collectivity, and is therefore well-suited to studying the dynamics and coexistence of shapes in atomic nuclei. For the first time, we analyze how these features in low-lying states of 6 Li and 12 C are impacted by the underlying realistic nucleon-nucleon interaction. We find that the interaction parametrization has a notable but limited effect on collective shapes in the lowest 6 Li and 12 C states, while collective structures in the excited 2 + state of 12 C are significantly more sensitive to the interaction parameters and exhibits emergent shape coexistence.
We study the 2D vertex operator algebra (VOA) construction in 4D N = 2 superconformal field theories on S 3 × S 1 , focusing on both old puzzles and new observations. The VOA lives on a two-torus T 2 ⊂ S 3 × S 1 , it is 1 2 Z -graded, and this torus is equipped with the natural choice of spin structure (1,0) for the Z + 1 2 -graded operators, corresponding to the NS sector vacuum character. By analyzing the possible refinements of the Schur index that preserves the VOA, we find that it admits discrete deformations, which allows access to the remaining spin structures (1,1), (0,1), and (0,0), of which the latter two involve the inclusion of a particular surface defect. For Lagrangian theories, we perform the detailed analysis: we describe the natural supersymmetric background, perform localization, and derive the gauged symplectic boson action on a torus in any spin structure. In the absence of flavor fugacities, the 2D and 4D path integrals precisely match, including the Casimir factors. We further analyze the 2D theory: we identify its integration cycle and the two-point functions and interpret flavor holonomies as screening charges in the VOA. Next, we make some observations about modularity; the T-transformation acts on our four partition functions and lifts to a large diffeomorphism on S 3 × S 1 . More interestingly, we generalize the four partition functions on the torus to an infinite family labeled by both the spin structure and the integration cycle inside the complexified maximal torus of the gauge group. Members of this family transform into one another under the full modular group, and we confirm the recent observation that the S-transform of the Schur index in Lagrangian theories exhibits logarithmic behavior. Finally, we comment on how locally our background reproduces the Ω-background.
The aim of this Tutorial is to give a pedagogical introduction into realizations of Majorana fermions, usually termed as Majorana bound states (MBSs), in condensed matter systems with magnetic textures. We begin by considering the Kitaev chain model of “spinless” fermions and show how two “half” fermions can appear at chain ends due to interactions. By considering this model and its two-dimensional generalization, we emphasize intricate relation between topological superconductivity and possible realizations of MBS. We further discuss how “spinless” fermions can be realized in more physical systems, e.g., by employing the spin-momentum locking. Next, we demonstrate how magnetic textures can be used to induce synthetic or fictitious spin–orbit interactions, and, thus, stabilize MBS. We describe a general approach that works for arbitrary textures and apply it to skyrmions. We show how MBS can be stabilized by elongated skyrmions, certain higher order skyrmions, and chains of skyrmions. We also discuss how braiding operations can be performed with MBS stabilized on magnetic skyrmions. Furthermore, this Tutorial is aimed at students at the graduate level.
Abstract Second-harmonic Hall voltage (SHV) measurement method has been widely used to characterize the strengths of spin–orbit torques (SOTs) in heavy metal/ferromagnet thin films saturated in the single-domain regime. Here, we show that the magnetic anisotropy of a W/Pt/Co trilayer can be robustly tuned from in-plane to out-of-plane by varying W, Pt, or Co thicknesses. Moreover, in samples with easy-cone anisotropy, SHV measurements exhibit anomalous ‘humps’ in the multidomain regime accessed by applying a nearly out-of-plane external magnetic field. These hump features can only be explained as a result of the formation of Néel-type domain walls, efficiently driven by nevertheless small SOTs in this double heavy metal heterostructure with canceling spin Hall angles.
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We report a comprehensive neutron scattering study of low energy magnetic excitations in the breathing pyrochlore helimagnetic Cu2OSeO3. Fully documenting the four lowest energy magnetic modes that leave the ferrimagnetic configuration of the “strong tetrahedra” intact (| ℏ ω| < 13 meV), we find gapless quadratic dispersion at the Γ point for energies above 0.2 meV, two doublets separated by 1.6(2) meV at the R point, and a bounded continuum at the X point. Our constrained rigid spin cluster model relates these features to Dzyaloshinskii-Moriya (DM) interactions and the incommensurate helical ground state. Combining conventional spin wave theory with a spin cluster form factor accurately reproduces the measured equal time structure factor through multiple Brillouin zones. An effective spin Hamiltonian describing complex anisotropic intercluster interactions is obtained.
Using ab initio density functional theory, we study herein the lattice phase transition of quasi-one-dimensional (TaSe 4 ) 2 I. In the undistorted state, the strongly anisotropic semimetal band structure presents two nonequivalent Weyl points. In previous efforts, two possible Ta-tetramerization patterns were proposed to be associated with the low-temperature structure. Our phonon calculations indicate that the orthorhombic F222 CDW-I phase is the most likely ground state for this quasi-one-dimensional system. In addition, the monoclinic C2 CDW-II phase may also be stable according to the phonon dispersion spectrum. Since these two phases have very similar energies in our density functional theory calculations, both these Ta-tetramerization distortions likely compete or coexist at low temperatures. The semimetal-to-insulator transition is induced by a Fermi-surface-driven instability that supports the Peierls scenario, which affects the Weyl physics developed above T CDW . Furthermore, the spin-orbit coupling generates Rashba-like band splittings in the insulating charge density wave phases.
In this paper, we consider a system of one-dimensional fermions moving in one direction, such as electrons at the edge of a quantum Hall system. At sufficiently long timescales the system is brought to equilibrium by weak interactions between the particles, which conserve their total number, energy, and momentum. The time evolution of the system near equilibrium is described by hydrodynamics based on the three conservation laws. We find that the system supports three sound modes. In the low-temperature limit one mode is a pure oscillation of particle density, analogous to the ordinary sound. The other two modes involve oscillations of both particle and entropy densities. In the presence of disorder, the first sound mode is strongly damped at frequencies below the momentum relaxation rate, whereas the other two modes remain weakly damped.
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