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NASA NTRS2021

NASA Engineering and Safety Center Technical Bulletin No. 21-03-1: Best Practices for the Elemental Profiling of High-Purity Hydrazine

Trace contaminants in high-purity hydrazine (HPH) propellant impact a wide variety of commercial, Department of Defense (DoD), and NASA missions. Depending on thruster design, elemental contaminants must be kept at extremely low levels and are verified as such by routine analysis. A number of these contaminants have recently undergone an assessment to shed light on their quantities present following changes in the HPH supply chain. A round robin analysis utilizing four separate laboratories resulted in unacceptably high variability in the quantification of these contaminants. The principal objective of this technical bulletin is to signal the availability of a new analysis methodology which yields accurate and repeatable quantification by providing best practices for both quantitation methodology and strategies for avoiding sample contamination during analysis.

High-Purity Hydrazine↗
NASA NTRSDate not supplied

Outcomes of a NASA Human Research Program’s (HRP) Space Radiation Element-sponsored Mini-Technical Interchange Meeting/workshop on Cardiovascular Disease Risk from Space Radiation

The NASA HRP’s Space Radiation Element funds research to characterize and mitigate adverse health outcomes from space radiation including cardiovascular risks to astronauts to enable deep space exploration and sustained human presence in space. Non-cancer effects such as damage to the cardiovascular system have been observed at clinically relevant high doses of ionizing radiation. However, an association between lower doses and risk of cardiovascular disease (CVD) remains somewhat controversial, especially in relation to the existence of low dose thresholds, radiation quality, and dose-rate effects, as well as gaps in characterizing the mechanisms and major pathways of disease. To facilitate, accelerate, and incubate new ideas to characterize and mitigate this risk, the Element is planning to organize a series of miniature technical interchange meetings (Tiny-TIMs) to provide a venue for HRP-funded investigators and thought leaders to present ongoing work and engage in open discussion on presented results, limitations of current approaches, incorporating better experimental strategies, model systems, etc. The initial Tiny-TIM held during the NASA HRP Investigators’ Workshop earlier this year – Upping the ante on characterizing and mitigating cardiovascular disease risk from space radiation exposure – aimed to stimulate discussion on the current state of scientific knowledge of CVD risk from space-like radiation exposure. The Tiny-TIM consisted of two 90-minute sessions; the first session concentrated on current knowledge of CVD risk from space radiation and the second session focused on innovative ideas, newer approaches, and techniques to accelerate research. The second session was followed by an open spirited discussion amongst peers on the current issues impeding the characterization of CVD risk from space radiation. The Element facilitated the discussion using a set of pressing open questions/gaps in knowledge that need to be addressed by the scientific community. The outcomes of the Tiny-TIM will be presented along with a plan of proposed future workshops and other initiatives of the Space Radiation Element.

Janapriya Saha↗
NASA NTRSDate not supplied

Implementation of Human Systems Integration Technical and Management Process for the Lunar Gateway Program

NASA recognizes Human Systems Integration (HSI) as part of the overall systems engineering and acquisition strategy for space systems. The Lunar Gateway Program is implementing HSI technical and management process across the lifecycle of the mission, as required by NPR 7123.1C NASA Systems Engineering Processes and Requirements, and led by the Gateway HSI team as required by NPR 8705.2C Human-Rating Requirements for Space Systems, now HEOMD-003 Crewed Deep Space Systems Human Rating Certification Requirements and Standards for NASA Missions. NASA has been using HSI principles for many years and has applied them to many of its previous human spaceflight Programs. As NASA returns to the Moon in a more sustainable manner, the Gateway Program is maturing the application of HSI by implementing it more visibly as part of Artemis, with guidance from the NASA/SP-20210010952 NASA HSI Handbook. This paper discusses how HSI is being implemented in the Gateway Program, challenges faced with its implementation during the development phase, and strategies/approaches used to overcome those. The paper also covers HSI implementation for flight systems, vehicle processing, and interfaces across the six identified NASA HSI Domains: human factors engineering, operations, safety, training, maintainability and supportability, habitability and environment. The goal is to provide an overview of the implementation process of HSI in the Gateway Program as an example for other Programs/Projects/Missionsthat are looking to implement HSI.

Jackelynne Silva-Martinez↗
NASA NTRSDate not supplied

Outcomes of a Mini Technical Interchange Meeting Concerning the Risk of Cardiovascular Disease from Exposure to Space Radiation

The NASA Human Research Program’s (HRP) Space Radiation Element (SRE) funds research to characterize and mitigate adverse health outcomes from exposure to space radiation to enable deep space exploration and sustained human presence in space. Damage to the cardiovascular system has been observed after exposure to clinically relevant doses of ionizing radiation. However, an association between lower radiation doses and cardiovascular disease (CVD) remains controversial, and questions pertaining to dose thresholds, radiation quality and dose-rate effects, and gaps in characterizing the mechanisms and major pathways of CVD remain. To solicit new ideas for characterizing and mitigating this risk, the SRE is organizing a series of miniature technical interchange meeting (Tiny-TIM) that provide a venue for HRP-funded investigators and thought leaders to present ongoing work and engage in open discussion on relevant topics. The initial Tiny-TIM: Upping the Ante on Characterizing and Mitigating Cardiovascular Disease Risk from Space Radiation Exposure, held at the NASA HRP Investigators’ Workshop (IWS) earlier this year, consisted of two 90-minute sessions; the first focused on current knowledge of CVD risk from space radiation exposure, and the second focused on innovative ideas, and newer approaches and techniques to accelerate research. The second session was followed by an open, spirited discussion amongst peers on the current issues impeding the characterization of CVD risk. SRE leadership facilitated the discussion using a set of pressing questions and gaps in knowledge that need to be addressed by the scientific community. This poster presents the outcomes of the Tiny-TIM, along with proposed future workshops and the SRE’s other initiatives.

Janapriya Saha↗
NASA NTRS2022

NIAC Phase-2 Final Report for Astrophysics and Technical Lab Studies of a Solar Neutrino Spacecraft Detector

The Sun provides all the energy that our planet needs for life and has been doing so for five billion years. Understanding our Sun and its interior is one of the major goals of the NASA Science program. Still this is a very difficult task because very little makes it directly out of the Sun’s interior. The energy we see today, that warms the Earth, was made 50,000 to 80,000 years ago and is only now coming to the surface to make light. However, neutrinos penetrate matter almost without interaction and make it to Earth in only eight minutes from creation. Since neutrinos interact only weakly they are hard to detect; never-the-less within the last ten years neutrino detectors on Earth have started to reliably detect neutrinos from the fusion reactions in the interior of the Sun and scientists have started to use this information to investigate the Sun’s nuclear furnace. Changes in solar neutrino flux make it advantageous to take a neutrino detector into space since the solar neutrino intensity changes dramatically as the inverse square of the distance from the Sun, by five orders of magnitude when going from the Earth to the Sun. Launch of a neutrino detector into space toward the Sun will: a) aim to significantly increase the neutrino flux 10,000x allowing for a smaller detector which improves detector energy resolution and performance, b) attempt to completely eliminate background terrestrial neutrino sources for improved measurement accuracy, and c) conduct unique science experiments near the Sun not achievable with much larger detectors on the Earth. NASA's interest in deep space exploration has been a key factor in its unmanned spacecraft development and launch of exploration science satellites and spacecraft. NASA has done exceptional experiments in space where science benefits from the unique platform of spacecraft that provides unprecedented views. For example, the Hubble Space Telescope is really a small and very common instrument, but when it is put into an orbit high above the Earth, it becomes one of the most powerful optical observatories man has ever made. Moving neutrino observations to space is the next obvious step. The concept of putting a neutrino detector in close orbit of the sun is completely unexplored and innovative. Its scientific return is to vastly enhance the understanding of the solar interior which is a NASA major goal as stated in the decadal survey. Preliminary calculations show that such a spacecraft if properly shielded, can operate in this environment both taking data of neutrino interactions which can be distinguished from random background rates of solar Electromagnetic emissions, Galactic charged cosmic-ray, and gamma-rays by using a double pulsed signature. The NIAC Phase-1 simulations have shown this idea to be very successful in eliminating background and identifying the neutrino interaction signal, hence this spacecraft detector concept once demonstrated to be Technical Readiness Level 7 and flight mission-ready would enable a whole new type of mission to explore and study our Sun, in details that could neither be done with the largest neutrino detectors on Earth nor other types of space-craft measurements that are not using neutrino detection. Our goal in this NIAC Phase-2 was to take the detector simulation ideas and construct a prototype for testing in the lab with tagged sources to evaluate and demonstrate that the performance in the simulations are borne out by a prototype.

Neutrino↗
NASA NTRSDate not supplied

NASA JetBlue Airways Technical Interchange

The Digital Information Sub-project will hold a Technical Interchange Meeting (TIM) with JetBlue Airways to discuss potential collaboration opportunities as well as discuss upcoming NASA-led demonstrations. This interchange meeting will solicit feedback from JetBlue for consideration of the sub-project in upcoming development and to encourage future participation and collaboration.

Digital Information Platform↗
NASA NTRSDate not supplied

NASA Delta Airlines Technical Interchange Meeting

The Digital Information Sub-project will hold a Technical Interchange Meeting (TIM) with Delta Airlines to discuss potential collaboration opportunities as well as discuss upcoming NASA-led demonstrations. This interchange meeting will solicit feedback from Delta for consideration of the sub-project in upcoming development and to encourage future participation and collaboration. Additionally, Delta will provide insight into airline operations to allow NASA to learn more about airline operations.

Digital Information Platform↗
NASA NTRS2022

CLASSY. II. A Technical Overview of the COS Legacy Archive Spectroscopic Survey

The COS Legacy Archive Spectroscopic SurveY (CLASSY) is designed to provide the community with a spectral atlas of 45 nearby star-forming galaxies that were chosen to cover similar properties to those seen at high z (z > 6). The prime high-level science product of CLASSY is accurately coadded UV spectra, ranging from ∼1000 to 2000 Å, derived from a combination of archival and new data obtained with HST's Cosmic Origins Spectrograph (COS). This paper details the multistage technical processes of creating this prime data product and the methodologies involved in extracting, reducing, aligning, and coadding far-ultraviolet and near-ultraviolet (NUV) spectra. We provide guidelines on how to successfully utilize COS observations of extended sources, despite COS being optimized for point sources, and best-practice recommendations for the coaddition of UV spectra in general. Moreover, we discuss the effects of our reduction and coaddition techniques in the scientific application of the CLASSY data. In particular, we find that accurately accounting for flux calibration offsets can affect the derived properties of the stellar populations, while customized extractions of NUV spectra for extended sources are essential for correctly diagnosing the metallicity of galaxies via C iii] nebular emission. Despite changes in spectral resolution of up to ∼25% between individual data sets (due to changes in the COS line-spread function), no adverse affects were observed on the difference in velocity width and outflow velocities of isolated absorption lines when measured in the final combined data products, owing in part to our signal-to-noise regime of S/N < 20.

Bethan L. James↗
NASA NTRS2023

Technical Basis Related to the Posture of NASA’s Office of Safety and Mission Assurance for the Launch of Radioactive Material Other than Space Nuclear Systems: Volume 1–Overview of Analysis and Results

NASA has launched and reentered payloads containing radioactive material for over 50 years. The isotopes, their quantity, and their form have varied significantly. The handling of this material prior to its integration into the spacecraft at the launch Center (and after its return to Earth after flight, if applicable) falls under the purview of the Office of the Chief Health and Medical Officer, while after the radioactive material is integrated into the spacecraft at the launch Center, it falls under the purview of the Office of Safety and Mission Assurance’s (OSMA) Nuclear Flight Safety Program. Historically, OSMA concurrence was required for any launch or reentry involving radioactive material. However, OSMA recently revisited this posture due to changes in the Federal policy in this area, and the significant accrued experience. The current report represents the more quantitative study envisioned in the recent change in posture. More specifically, this document addresses the potential risks and other considerations associated with launching small quantities of radioactive material (below the level requiring the Federally-mandated process in National Security Presidential Memorandum- (NSPM-) 20, “Presidential Memorandum on Launch of Spacecraft Containing Space Nuclear Systems” (USG, 2019) to provide the technical basis for when such activities require OSMA concurrence versus notification, as it relates to nuclear flight safety.

Don Helton↗
NASA NTRSDate not supplied

Conclusions of a Mini Technical Interchange Meeting on Mechanisms and Pathways Common Between Adverse Health Outcomes from Exposures to Space Radiation

To enable deep space exploration and sustained human presence in space, the NASA Human Research Program’s (HRP) Space Radiation Element (SRE) funds research to characterize and mitigate adverse health outcomes from exposure to space radiation that include risks of carcinogenesis, cardiovascular disease (CVD) and central nervous system (CNS) decrements. Over the past decade, a growing body of compelling experimental evidence suggests shared mechanisms and pathophysiological processes for CVD, neurodegenerative effects, and cancer development and progression, which are traditionally managed as separate disease processes. Additionally, epidemiological studies have identified cross-sectional and longitudinal associations between some specific types of cancer and CVD, and accumulating evidence indicates that the pathogenesis of neurodegenerative diseases such as Alzheimer’s disease may overlap with CVD and cancer pathogenesis. Identifying the mechanisms and pathways common to these important health decrements will not only accelerate development of effective countermeasures and improve management of spaceflight-induced risk, it will also help to develop new treatment strategies for patients on Earth. To identify common pathways and mechanisms of disease induction and progression from current SR-funded studies and to inform future work and solicitations, the SRE organizes themed sessions at annual HRP Investigators’ Workshops (IWS). These technical interchange meetings (TIMs) provide a venue for the scientific community to present ongoing work and engage in open discussion on results, limitations of current approaches, and incorporation of novel experimental strategies, model systems, and other innovative techniques. Here a summary and lessons learned from the SRE-sponsored mini-TIM titled “mechanisms and pathways common between adverse health outcomes” held at HRP IWS 2023 will be communicated. The 90-min TIM had 30-min dedicated to discussing and developing potential collaboration and tissue sharing opportunities among investigators. The SRE facilitated the discussion using a set of pressing questions and gaps in knowledge that need to be addressed by the scientific community. This poster presents the outcomes of the session along with proposed future workshops and other SRE initiatives.

Janapriya Saha↗
NASA NTRSDate not supplied

800 °C Demonstrated kHz SiC IC Electronics and Pressure Sensors as Technical Foundation for Realizing MHz DARPA HOTS Goals

The HOTS program will develop a technology for high-bandwidth, high-dynamic-range sensing at high temperature. Performance will be validated through the development and demonstration of a pressure sensor module (i.e., integrated transducer and signal-conditioning microelectronics) achieving the following performance goals: NASA Glenn has unique technology experience in extreme environment pressure sensors & IC electronics, including at 800 °C in air, providing significant risk reduction in meeting DARPA HOTS goals. Appropriate partnership and tech transfer should accelerate realization of DARPA HOTS hard technical challenges.

SiC pressure sensor electronics high temperature↗
NASA NTRSDate not supplied

Conclusions of a Mini Technical Interchange Meeting on Mechanisms and Pathways Common Between Adverse Health Outcomes from Exposures to Space Radiation

To enable deep space exploration and sustained human presence in space, the NASA Human Research Program’s (HRP) Space Radiation Element (SRE) funds research to characterize and mitigate adverse health outcomes from exposure to space radiation that include risks of carcinogenesis, cardiovascular disease (CVD) and central nervous system (CNS) decrements. Over the past decade, a growing body of compelling experimental evidence suggests shared mechanisms and pathophysiological processes for CVD, neurodegenerative effects, and cancer development and progression, which are traditionally managed as separate disease processes. Additionally, epidemiological studies have identified cross-sectional and longitudinal associations between some specific types of cancer and CVD, and accumulating evidence indicates that the pathogenesis of neurodegenerative diseases such as Alzheimer’s disease may overlap with CVD and cancer pathogenesis. Identifying the mechanisms and pathways common to these important health decrements will not only accelerate development of effective countermeasures and improve management of spaceflight-induced risk, it will also help to develop new treatment strategies for patients on Earth. To identify common pathways and mechanisms of disease induction and progression from current SR-funded studies and to inform future work and solicitations, the SRE organizes themed sessions at annual HRP Investigators’ Workshops (IWS). These technical interchange meetings (TIMs) provide a venue for the scientific community to present ongoing work and engage in open discussion on results, limitations of current approaches, and incorporation of novel experimental strategies, model systems, and other innovative techniques. Here a summary and lessons learned from the SRE-sponsored mini-TIM titled “mechanisms and pathways common between adverse health outcomes” held at HRP IWS 2023 will be communicated. The 90-min TIM had 30-min dedicated to discussing and developing potential collaboration and tissue sharing opportunities among investigators. The SRE facilitated the discussion using a set of pressing questions and gaps in knowledge that need to be addressed by the scientific community. This poster presents the outcomes of the session along with proposed future workshops and other SRE initiatives.

Janapriya Saha↗
NASA NTRS2023

Technical Note: NASAaccess – A Tool for Access, Reformatting, and Visualization of Remotely Sensed Earth Observation and Climate Data

The National Aeronautics and Space Administration (NASA) has launched a new initiative, the Open-Source Science Initiative (OSSI), to enable and support science towards openness. The OSSI supports open-source software development and dissemination. In this work, we present NASAaccess, which is an open-source software package and web-based environmental modeling application for earth observation data accessing, reformatting, and presenting quantitative data products. The main objective of developing the NASAaccess platform is to facilitate exploration, modeling, and understanding of earth data for scientists, stakeholders, and concerned citizens whose objectives align with the new OSSI goals. The NASAaccess platform is available as software packages (i.e., the R and conda packages) as well as an interactive-format web-based environmental modeling application for earth observation data developed with Tethys Platform. NASAaccess has been envisioned as lowering the technical barriers and simplifying the process of accessing scalable distributed computing resources and leveraging additional software for data and computationally intensive modeling frameworks. Specifically, NASAaccess has been developed to meet the need for seamless earth observation remote-sensing and climate data ingestion into various hydrological modeling frameworks. Moreover, NASAaccess is also contributing to keeping interested parties and stakeholders engaged with environmental modeling, accessing the information available in various remote-sensing products. NASAaccess' current capabilities cover various NASA datasets and products that include the Global Precipitation Measurement (GPM) data products, the Global Land Data Assimilation System (GLDAS) land surface states and fluxes, and the NASA Earth Exchange Global Daily Downscaled Projections (NEX-GDDP) Coupled Model Intercomparison Project Phase 5 (CMIP5) and Coupled Model Intercomparison Project Phase 6 (CMIP6) climate change dataset products.

Ibrahim Nourein Mohammed↗
NASA NTRS2023

NASA Engineering and Safety Center Technical Bulletin No. 23-07: Best Practices for Fabrication of Microelectronic Devices

Material degradation during the fabrication of microelectronic devices has plagued the space industry for many years owing to the layering of many dissimilar metals to create these devices. Often, commonly used materials and systems are overlooked as potential sources of material degradation. This technical bulletin highlights extensive research to isolate probable causes of this degradation.

Best Practices↗
NASA NTRSDate not supplied

Verification and Validation of a Conceptual Model of the Auto-Rigging Payload Handling and Off-Loading System Using LEGO Technic System and Three-Dimensional Printed Parts

A conceptual model (CM) can be used to validate a concept in modeling and simulation life cycles. During the 2020-2022 Coronavirus disease 2019 (COVID-19) pandemic, for employee safety NASA implemented center closures and mandatory telework for the entire workforce. During this challenging time, engineers and researchers at NASA Langley Research Center (LaRC) looked for safe and innovative approaches and methods to continue the development of CMs for various projects. Engineers and researchers at LaRC researched Auto-Rigging Payload Handling and Off-Loading System (ARPHOLS) for payload handing and off-loading a system on an inclined lunar lander deck. In this paper, the development of a CM and the verification and validation of a conceptual idea for ARPHOLS using a LEGO Technic system and three-dimensional printed parts is presented.

Design↗
NASA NTRS2023

Earth Independent Medical Operations (EIMO) Training Technical Interchange Meeting, 26th October 2023: Background and Summary of Discussion

On 26th October 2023, ExMC convened a panel of Subject Matter Experts (SMEs) from NASA, broadly representing Headquarters, the Human Research Program, Medical Operations, the Human Health and Performance Directorate at JSC, the Health and Medical Technical Authority, the Flight Operations Directorate, and representation from other Centers including: Ames Research Center (ARC), and Glenn Research Center (GRC). Representatives from the Canadian Space Agency also participated in this TIM. In addition, SMEs from industry included representation from the following entities: Axiom Space, Space Exploration Technologies Corporation, Level Ex, Shiny Box Interactive. Additional SMEs from academia included: University of Houston, Touro University, Weill Cornell Medical College and the Translational Research Institute for Space Health at Baylor College of Medicine. This group of stakeholders discussed the training issues related to facilitating EIMO. Sub-topics for this discussion included the following: - Pre-launch medical curriculum development - Ground-based training on medical hardware - Dental health - Behavioral health - Telemedicine - Just-in-time training - Simulation-based training (extended reality)

CMO Training↗
NASA NTRS2010

NASA Engineering and Safety Center Technical Bulletin No. 10-02: Potential Failure of Dual Simultaneously Initiated Pyrotechnic Operated Valves

The NASA Engineering and Safety Center (NESC) Technical Bulletin No. 09-01 reported an independent investigation of four pyrovalve failures that occurred while using aluminum (Al) pyrovalve primer chamber assemblies (PCAs) during ground testing. The investigation revealed that simultaneous firing (within a few microseconds) of the NASA Standard Initiators (NSIs) was the primary reason why the booster charge failed to ignite and the pyrovalves subsequently failed to operate. A second investigation of a new stainless steel (SS) PCA design with separate flame channels was completed in 2010. The new SS configuration was found to be improved in most respects; however, no improvement was noted in the temperature delivered to ignite the booster during dual simultaneous NSI firings. Simultaneous firings should be avoided when using either the Al or the SS PCA design.

Potential Failure↗
NASA NTRSDate not supplied

Conclusions of A Mini Technical Interchange Meeting on New Cross Risk Integration Projects Managed By the NASA Space Radiation Element

To enable deep space exploration and sustained human presence in space, the NASA Human Research Program’s (HRP) Space Radiation Element (SRE) funds research to characterize and mitigate adverse health outcomes from exposure to space radiation. Recently, the Space Radiation Element was tasked with supporting multiple HRP Elements with innovative and enabling projects to inform risk characterization, facilitate mitigation activities, and support crew health and performance. These projects, such as precision health initiative, NASA Omics Archive (NOA) and human sample repositories, are agnostic to any HRP Element, hence the name, Cross Risk Integration Projects (CRIP). CRIP serves three broad purposes: Services: Generate samples/data or manage the receipt, inventory, archive and ultimate redistribution of biospecimens created in HRP-funded spaceflight and analog research activities – includes NASA Omics Archive (NOA) project and various human and animal sample repositories. Method Development: Identify and evaluate, new-to-NASA research or analysis methods or techniques – includes TRRaC (Translational Radiation Research and Countermeasures) Project. Enabling Capabilities: Demonstrate real world application by adapting, adopting and/or developing capabilities to benefit crew health & performance and improve risk – includes Precision Health Initiative (Pharmacogenomics) and advanced biological systems and engineered tissue microsystems initiative (tissue chips, organ-on-a-chip). To identify new technologies, future work, and solicitations, the SRE organizes themed sessions at annual HRP Investigators’ Workshops (IWS). These technical interchange meetings (TIMs) provide a venue for the scientific community to present ongoing work and engage in open discussion, limitations of current approaches, and incorporation of novel experimental strategies and other innovative techniques. Here a summary and lessons learned from the SRE-sponsored mini-TIM titled “Space Radiation Cross Risk Integrations Projects” at HRP IWS 2024 will be communicated. The 90-min TIM had 6 speakers who presented impressive novel ideas and work This poster presents the outcomes of the session along with proposed future workshops and other SRE initiatives.

Janapriya Saha↗