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Search indexed NASA NTRS and DOE OSTI research on propulsion, heat transfer, battery materials and energy systems. Follow report and document links to the original sources.

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At least 793 records · Page 44
All sourcesNASA NTRSDOE OSTI
NASA NTRS1978

Changes in the human blood coagulating system during prolonged hypokinesia

Changes in the coagulating system of the blood were studied in six subjects during prolonged hypokinesia. Thrombogenic properties of the blood rose in all cases on the 8th day. These changes are explained by stress reaction due to unusual conditions for a healthy person. Changes in the blood coagulating system in the group subjected to physical exercise and without it ran a practically parallel course. Apparently physical exercise is insufficient to prevent such changes that appear in the coagulating system of the blood during prolonged hypokinesia.

Filatova, L. M.↗
NASA NTRS1985

A detailed analysis of the erythropoietic control system in the human, squirrel, monkey, rat and mouse

The erythropoiesis modeling performed in support of the Body Fluid and Blood Volume Regulation tasks is described. The mathematical formulation of the species independent model, the solutions to the steady state and dynamic versions of the model, and the individual species specific models for the human, squirrel monkey, rat and mouse are outlined. A detailed sensitivity analysis of the species independent model response to parameter changes and how those responses change from species to species is presented. The species to species response to a series of simulated stresses directly related to blood volume regulation during space flight is analyzed.

Nordheim, A. W.↗
NASA NTRS1986

Virtual interface environment

A head-mounted, wide-angle, stereoscopic display system controlled by operator position, voice and gesture has been developed for use as a multipurpose interface environment. The system provides a multisensory, interactive display environment in which a user can virtually explore a 360-degree synthesized or remotely sensed environment and can viscerally interact with its components. Primary applications of the system are in telerobotics, management of large-scale integrated information systems, and human factors research. System configuration, application scenarios, and research directions are described.

Fisher, Scott S.↗
NASA NTRS1987

Virtual workstation - A multimodal, stereoscopic display environment

A head-mounted, wide-angle, stereoscopic display system controlled by operator position, voice and gesture has been developed for use in a multipurpose interface environment. The system provides a multisensory, interactive display environment in which a user can virtually explore a 360-degree synthesized or remotely sensed environment and can viscerally interact with its components. Primary applications of the system are in telerobotics, management of large-scale integrated information systems, and human factors research. System configuration, application scenarios, and research directions are described.

Fisher, S. S.↗
NASA NTRS1988

Virtual interface environment workstations

A head-mounted, wide-angle, stereoscopic display system controlled by operator position, voice and gesture has been developed at NASA's Ames Research Center for use as a multipurpose interface environment. This Virtual Interface Environment Workstation (VIEW) system provides a multisensory, interactive display environment in which a user can virtually explore a 360-degree synthesized or remotely sensed environment and can viscerally interact with its components. Primary applications of the system are in telerobotics, management of large-scale integrated information systems, and human factors research. System configuration, research scenarios, and research directions are described.

Fisher, S. S.↗
NASA NTRS1991

NASA Ames aerospace systems directorate research

The Aerospace Systems Directorate is one of four research directorates at the NASA Ames Research Center. The Directorate conducts research and technology development for advanced aircraft and aircraft systems in intelligent computational systems and human-machine systems for aeronautics and space. The Directorate manages research and aircraft technology development projects, and operates and maintains major wind tunnels and flight simulation facilities. The Aerospace Systems Directorate's research and technology as it relates to NASA agency goals and specific strategic thrusts are discussed.

Albers, James A.↗
NASA NTRS1993

Development of biomechanical models for human factors evaluations

Computer aided design (CAD) techniques are now well established and have become the norm in many aspects of aerospace engineering. They enable analytical studies, such as finite element analysis, to be performed to measure performance characteristics of the aircraft or spacecraft long before a physical model is built. However, because of the complexity of human performance, CAD systems for human factors are not in widespread use. The purpose of such a program would be to analyze the performance capability of a crew member given a particular environment and task. This requires the design capabilities to describe the environment's geometry and to describe the task's requirements, which may involve motion and strength. This in turn requires extensive data on human physical performance which can be generalized to many different physical configurations. PLAID is developing into such a program. Begun at Johnson Space Center in 1977, it was started to model only the geometry of the environment. The physical appearance of a human body was generated, and the tool took on a new meaning as fit, access, and reach could be checked. Specification of fields-of-view soon followed. This allowed PLAID to be used to predict what the Space Shuttle cameras or crew could see from a given point.

Woolford, Barbara↗
NASA NTRS2003

Advantages of Brahms for Specifying and Implementing a Multiagent Human-Robotic Exploration System

We have developed a model-based, distributed architecture that integrates diverse components in a system designed for lunar and planetary surface operations: an astronaut's space suit, cameras, all-terrain vehicles, robotic assistant, crew in a local habitat, and mission support team. Software processes ('agents') implemented in the Brahms language, run on multiple, mobile platforms. These mobile agents interpret and transform available data to help people and robotic systems coordinate their actions to make operations more safe and efficient. The Brahms-based mobile agent architecture (MAA) uses a novel combination of agent types so the software agents may understand and facilitate communications between people and between system components. A state-of-the-art spoken dialogue interface is integrated with Brahms models, supporting a speech-driven field observation record and rover command system. An important aspect of the methodology involves first simulating the entire system in Brahms, then configuring the agents into a runtime system Thus, Brahms provides a language, engine, and system builder's toolkit for specifying and implementing multiagent systems.

Clancey, William J.↗
NASA NTRS2003

The Human Sympathetic Nervous System Response to Spaceflight

The sympathetic nervous system is an important part of the autonomic (or automatic) nervous system. When an individual stands up, the sympathetic nervous system speeds the heart and constricts blood vessels to prevent a drop in blood pressure. A significant number of astronauts experience a drop in blood pressure when standing for prolonged periods after they return from spaceflight. Difficulty maintaining blood pressure with standing is also a daily problem for many patients. Indirect evidence available before the Neurolab mission suggested the problem in astronauts while in space might be due partially to reduced sympathetic nervous system activity. The purpose of this experiment was to identify whether sympathetic activity was reduced during spaceflight. Sympathetic nervous system activity can be determined in part by measuring heart rate, nerve activity going to blood vessels, and the release of the hormone norepinephrine into the blood. Norepinephrine is a neurotransmitter discharged from active sympathetic nerve terminals, so its rate of release can serve as a marker of sympathetic nervous system action. In addition to standard cardiovascular measurements (heart rate, blood pressure), we determined sympathetic nerve activity as well as norepinephrine release and clearance on four crewmembers on the Neurolab mission. Contrary to our expectation, the results demonstrated that the astronauts had mildly elevated resting sympathetic nervous system activity in space. Sympathetic nervous system responses to stresses that simulated the cardiovascular effects of standing (lower body negative pressure) were brisk both during and after spaceflight. We concluded that, in the astronauts tested, the activity and response of the sympathetic nervous system to cardiovascular stresses appeared intact and mildly elevated both during and after spaceflight. These changes returned to normal within a few days.

Ertl, Andrew C.↗
NASA NTRS1992

Chromosomal changes in cultured human epithelial cells transformed by low- and high-LET radiation

For a better assessment of radiation risk in space, an understanding of the responses of human cells, especially the epithelial cells, to low- and high-LET radiation is essential. In our laboratory, we have successfully developed techniques to study the neoplastic transformation of two human epithelial cell systems by ionizing radiation. These cell systems are human mammary epithelial cells (H184B5) and human epidermal keratinocytes (HEK). Both cell lines are immortal, anchorage dependent for growth, and nontumorigenic in athymic nude mice. Neoplastic transformation was achieved by irradiating cells successively. Our results showed that radiogenic cell transformation is a multistep process and that a single exposure of ionizing radiation can cause only one step of transformation. It requires, therefore, multihits to make human epithelial cells fully tumorigenic. Using a simple karyotyping method, we did chromosome analysis with cells cloned at various stages of transformation. We found no consistent large terminal deletion of chromosomes in radiation-induced transformants. Some changes of total number of chromosomes, however, were observed in the transformed cells. These transformants provide an unique opportunity for further genetic studies at a molecular level.

NASA Discipline Number 04-10↗
NASA NTRS2005

National Research Council Dialogue to Assess Progress on NASA's Human Health & Support Systems Capability Roadmap Development: General Background and Introduction

Contents include the following: General Background and Introduction of Capability Roadmaps. Agency Objective. Strategic Planning Transformation. Advanced Planning Organizational Roles. Public Involvement in Strategic Planning. Strategic Roadmaps and Schedule. Capability Roadmaps and Schedule. Purpose of NRC Review. Capability Roadmap Development (Progress to Date).

Aikins, Jan↗
NASA NTRS2005

Human Planetary Landing System (HPLS) Capability Roadmap NRC Progress Review

Capability Roadmap Team. Capability Description, Scope and Capability Breakdown Structure. Benefits of the HPLS. Roadmap Process and Approach. Current State-of-the-Art, Assumptions and Key Requirements. Top Level HPLS Roadmap. Capability Presentations by Leads. Mission Drivers Requirements. "AEDL" System Engineering. Communication & Navigation Systems. Hypersonic Systems. Super to Subsonic Decelerator Systems. Terminal Descent and Landing Systems. A Priori In-Situ Mars Observations. AEDL Analysis, Test and Validation Infrastructure. Capability Technical Challenges. Capability Connection Points to other Roadmaps/Crosswalks. Summary of Top Level Capability. Forward Work.

Manning, Rob↗
NASA NTRS2005

Aerocapture, Entry, Descent and Landing (AEDL) Human Planetary Landing Systems. Section 10: AEDL Analysis, Test and Validation Infrastructure

Contents include the following: 3 Listing of critical capabilities (knowledge, procedures, training, facilities) and metrics for validating that they are mission ready. Examples of critical capabilities and validation metrics: ground test and simulations. Flight testing to prove capabilities are mission ready. Issues and recommendations.

Arnold, J.↗
NASA NTRS2009

Launch Order, Launch Separation, and Loiter in the Constellation 1 1/2-Launch Solution

The NASA Constellation Program (CxP) is developing a two-element Earth-to-Orbit launch system to enable human exploration of the Moon. The first element, Ares I, is a human-rated system that consists of a first stage based on the Space Shuttle Program's solid rocket booster (SRB) and an upper stage that consists of a four-crew Orion capsule, a service module, and a Launch Escape System. The second element, Ares V, is a Saturn V-plus category launch system that consists of the core stage with a cluster of six RS-68B engines and augmented with two 5.5-segment SRBs, a Saturn-derived J-2X engine powering an Earth Departure Stage (EDS), and the lunar-lander vehicle payload, Altair. Initial plans called for the Ares V to be launched first, followed the next day by the Ares I. After the EDS performs the final portion of ascent and subsequent orbit circularization, the Orion spacecraft then performs a rendezvous and docks with the EDS and its Altair payload. Following checkout, the integrated stack loiters in low Earth orbit (LEO) until the appropriate Trans-Lunar Injection (TLI) window opportunity opens, at which time the EDS propels the integrated Orion Altair to the Moon. Successful completion of this 1 1/2-launch solution carries risks related to both the orbital lifetime of the assets and the probability of achieving the launch of the second vehicle within the orbital lifetime of the first. These risks, which are significant in terms of overall system design choices and probability of mission success, dictated a thorough reevaluation of the launch strategy, including the order of vehicle launch and the planned time period between launches. The goal of the effort described in this paper was to select a launch strategy that would result in the greatest possible expected system performance, while accounting for launch risks and the cost of increased orbital lifetime. Discrete Event Simulation (DES) model of the launch strategies was created to determine the probability of a second launch not occurring in a timely fashion (i.e., before the assets waiting in LEO expire). An overview of the launch strategy evaluation process is presented, along with results of specific cases that were analyzed. A high-level comparison of options is then presented, along with the conclusion derived from the analysis.

Stromgren, Chel↗