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At least 775 records · Page 43

PepCon proteomics standards and methods of use

Described are methods, compositions, and devices for a concatemeric protein standard that behaves as a protein but transforms into single peptides upon digestion, which is optimized to function as a non-obtrusive process control for mass spectrometry analysis.

Lyman, Mathew Gerald↗

GOLEM: GOld standard for Learning and Evaluation of Motifs

Motifs are distinctive, recurring, widely used idiom-like words or phrases, often originating from folklore, whose meaning is anchored in a narrative and have a significance as communicative devices across a wide range of media, including news, literature, and propaganda. Many motifs concisely imply a large constellation of culturally relevant information, and their broad usage suggests their cognitive importance as touchstones of cultural knowledge. As such, their detection is a step towards culturally aware natural language processing. We present GOLEM (GOld standard for Learning and Evaluation of Motifs) a dataset of English news articles, opinion pieces, and broadcast transcripts annotated for motific information. The dataset identifies 25,737 motif candidates across 34 motif types drawn from three cultural or national groups: Jewish, Irish, and Puerto Rican. The dataset contains 2,024,141 words split into 25,737 text snippets drawn from 8,073 articles. Each motif candidate is labeled according to a scheme which identifies the type of usage (motific, referential, eponymic, or unrelated), resulting in 1,743 actual motific instances in the data. Annotation was performed by individuals identifying as members of each group and achieved a Fleiss’ kappa (?) of > 0.55. In addition to the data, we demonstrate that classification of the candidate type is a challenging task for Large Language Models (LLMs) using a few-shot approach; recent models such as T5, FLAN-T5, GPT-2, and Llama 2 (7B) achieved a performance of 41% accuracy at best, where the majority class accuracy is 41% and the average chance accuracy is 27%. These data will support development of new models and approaches for detecting (and reasoning about) motific information in text.

motif, culture, natural language, artificial intel↗

Novel Photonuclear Methods to Produce an Argon-37 Standard

The mission of this research is to explore novel photonuclear-based pathways into the production of 37Ar. Above-background detection levels of 37Ar uniquely indicates the occurrence of an underground nuclear explosion, produced from fission neutrons interacting in the surrounding environment through the 40Ca(n,a)37Ar reaction. The half-life of 35 days allows on-site inspectors (OSI) adequate time following the nuclear event to detect 37Ar and verify compliance or defiance of non-proliferation treaties such as the Comprehensive Nuclear-Test-Ban Treaty (CTBT). An 37Ar standard would give OSI the ability to calibrate their detectors and measure detector efficiency allowing for the quantification of detected activity, give OSI authentic samples to test detectors in field exercises, and improve models predicting diffusion pathways of 37Ar through the underground environment.

43 PARTICLE ACCELERATORS↗

The Linear Point Standard Ruler with DESI DR1 and DR2 Data

The linear point, a purely geometric feature in the monopole of the two-point correlation function, has been proposed as an alternative standard ruler. Compared to the peak in the correlation function, it is more robust to late-time nonlinear effects at the percent level. In light of improved simulations and high quality data, we revisit the robustness of the linear point and use it as an alternative to template-based fitting approaches typically used in BAO analyses. We present the linear point measurements on galaxy samples from the first and second data releases (DR1 and DR2) of the DESI survey. We convert the linear point into a dimensionless parameter $α_{iso,LP}$, defined as the ratio of the linear point in the fiducial cosmology and the observed value, analogous to the isotropic BAO scaling parameter $α_{iso}$ used in previous BAO measurements. Using the 2nd generation of AbacusSummit mock catalogs, we find that linear point measurements are more precise when calculated in the post-reconstruction regime with 15-60% smaller uncertainties than those pre-reconstruction. We find a systematic shift in the linear point measurements compared against the isotropic BAO measurements in mocks; we attribute this to the isotropic damping parameter responsible for smearing the linear point in the nonlinear regime. We propose a sample-dependent correction that mitigates the impact of late-time nonlinear effects. While this introduces a cosmology dependence in an otherwise model-independent measurement, this is necessary given the sub-percent precision dictated by current cosmological surveys. Comparing $α_{iso,LP}$ with isotropic BAO measurements made on the DESI DR1 and DR2 galaxy samples, we find excellent agreement after applying this correction, particularly post-reconstruction. We discuss future scope regarding cosmological inference with linear point measurements.

Uberoi, N. [Yale U.] (ORCID:0000000275179629)↗

A Quantum Computational Determination of the Weak Mixing Angle in the Standard Model

The weak mixing angle $s_W$ is a fundamental constant in the Standard Model (SM) and measured at the $Z$ boson mass to be $\widehat{s}^2_W(m_Z) = 0.23129 \pm 0.00004$ in the $\overline{\rm MS}$ renormalization scheme, where $m_Z=91.2\ \text{GeV}$. On the other hand, non-stabilizerness - the magic - characterizes the computational advantage of a quantum system over classical computers. We consider the production of magic from stabilizer initial states, which carry zero magic, in the 2-to-2 scattering of charged leptons in the SM at the tree level, which is mediated by the photon and the $Z$ boson. Using the second order stabilizer Rényi entropy, and averaging over all 60 initial stabilizer states and the scattering angle, we compute and minimize the magic production as a function of $s^2_W$ in the Møller scattering $e^-e^-\to e^-e^-$, which is free of kinematic thresholds. At the centre-of-mass energy $\sqrt{s}=m_Z$, there is a unique minimum in magic production at $\mathbf{s}^{2}_W(m_Z)=0.2317$, which agrees with the measured $\widehat{s}^2_W(m_Z)$ at the sub-percent level. At higher energies, the magic-minimizing $\mathbf{s}^{2}_W$ continues to agree with the empirical value at the percent level or better, up to 10 TeV. The finding suggests the electroweak sector of the SM tends to generate minimal quantum resources from the computational viewpoint.

Liu, Qiaofeng [Northwestern U.]↗

A Quantum Computational Determination of the Weak Mixing Angle in the Standard Model

The weak mixing angle $s_W$ is a fundamental constant in the Standard Model (SM) and measured at the $Z$ boson mass to be $\widehat{s}^2_W(m_Z) = 0.23129 \pm 0.00004$ in the $\overline{\rm MS}$ renormalization scheme, where $m_Z=91.2\ \text{GeV}$. On the other hand, non-stabilizerness - the magic - characterizes the computational advantage of a quantum system over classical computers. We consider the production of magic from stabilizer initial states, which carry zero magic, in the 2-to-2 scattering of charged leptons in the SM at the tree level, which is mediated by the photon and the $Z$ boson. Using the second order stabilizer Rényi entropy, and averaging over all 60 initial stabilizer states and the scattering angle, we compute and minimize the magic production as a function of $s^2_W$ in the Møller scattering $e^-e^-\to e^-e^-$, which is free of kinematic thresholds. At the centre-of-mass energy $\sqrt{s}=m_Z$, there is a unique minimum in magic production at $\mathbf{s}^{2}_W(m_Z)=0.2317$, which agrees with the measured $\widehat{s}^2_W(m_Z)$ at the sub-percent level. At higher energies, the magic-minimizing $\mathbf{s}^{2}_W$ continues to agree with the empirical value at the percent level or better, up to 10 TeV. The finding suggests the electroweak sector of the SM tends to generate minimal quantum resources from the computational viewpoint.

Liu, Qiaofeng [Northwestern U.]↗

Machine Learning based Correlation of the Mechanical Properties of Sub-sized and Standard-sized Specimens

Mechanical testing with sub-sized specimens is essential in the nuclear industry, offering the ability to conduct tests in confined spaces with lower irradiation and expediting material qualification. However, smaller specimens exhibit different material behavior across scales, a phenomenon known as the "specimen size effect". In this study, we compiled over 1,000 tensile testing records, covering 54 parameters such as material type, composition, manufacturing details, irradiation conditions, specimen dimensions, and tensile properties through a comprehensive literature review. We focus on correlating sub-sized and standard specimens’ tensile mechanical properties on SS316 alloy, which has the most extensive dataset available. We explore ML-based models and uncertainty quantification for tensile properties, analyze key factors influencing these properties, and compare the effectiveness of ML models with existing analytical methods in addressing the specimen size effect.

tensile properties↗

A Quantum Computational Determination of the Weak Mixing Angle in the Standard Model

The weak mixing angle $s_W$ is a fundamental constant in the Standard Model (SM) and measured at the $Z$ boson mass to be $\widehat{s}^2_W(m_Z) = 0.23129 \pm 0.00004$ in the $\overline{\rm MS}$ renormalization scheme, where $m_Z=91.2\ \text{GeV}$. On the other hand, non-stabilizerness - the magic - characterizes the computational advantage of a quantum system over classical computers. We consider the production of magic from stabilizer initial states, which carry zero magic, in the 2-to-2 scattering of charged leptons in the SM at the tree level, which is mediated by the photon and the $Z$ boson. Using the second order stabilizer Rényi entropy, and averaging over all 60 initial stabilizer states and the scattering angle, we compute and minimize the magic production as a function of $s^2_W$ in the Møller scattering $e^-e^-\to e^-e^-$, which is free of kinematic thresholds. At the centre-of-mass energy $\sqrt{s}=m_Z$, there is a unique minimum in magic production at $\mathbf{s}^{2}_W(m_Z)=0.2317$, which agrees with the measured $\widehat{s}^2_W(m_Z)$ at the sub-percent level. At higher energies, the magic-minimizing $\mathbf{s}^{2}_W$ continues to agree with the empirical value at the percent level or better, up to 10 TeV. The finding suggests the electroweak sector of the SM tends to generate minimal quantum resources from the computational viewpoint.

Liu, Qiaofeng [Northwestern U.]↗

Standard Candles for Supernova Neutrino Detection at DUNE

The Deep Underground Neutrino Experiment (DUNE) far detector is sensitive to $\mathcal{O}(10)$ MeV electron neutrinos through $ν_e$ charged-current reaction with argon. This capability is a unique window into the $ν_e$ component of a Galactic core-collapse supernova flux. Extracting the properties of the supernova spectrum is, however, limited by the poorly-known $ν_e$-Ar cross section. We propose a data-driven strategy that leverages $^8$B solar neutrinos and muon-decay-at-rest neutrinos as standard candles for this process. These calibration samples constrain both the low-energy and high-energy components of the cross section relevant for supernova detection. Our method reduces the reliance on nuclear models, which can bias the extraction of the spectral parameters by as much as 300$\%$.

Cheng, Ting [Fermilab]↗

Real-Time Anomaly Detection for Searches Beyond the Standard Model in the ProtoDUNE Horizontal Drift Detector

This paper summarizes work conducted throughout a SULI internship at Fermi National Accelerator Laboratory focused on building an unsupervised machine learning model for real-time anomaly detection in ProtoDUNE Horizontal Drift. Using simulated data, we trained an autoencoder model on a pure cosmic dataset, and evaluated it on both cosmic and neutrino events—making the model an anomaly detector. The goal was to make a model which matches or exceeds the current ADC Simple Window trigger algorithm so that our model can perform at the same rate but provide sensitivity to potential beyond-the-Standard-Model (BSM) signatures. In the end, we were able to construct a model which slightly exceeds the capabilities of the ADC Simple Window while remaining completely unsupervised, achieving 31.9 ± 0.2% (26.6 ± 0.2%) ν efficiency at 5 Hz (2 Hz), a 3.6 (3.2) percentage point increase. Additionally, 17.5 ± 0.3% (18.3 ± 0.3%) of the events that passed the autoencoder at 5 Hz (2 Hz) were missed by the current trigger algorithm. Future work will investigate alternative normalization methods, including quantile transformation, and evaluate the model on ProtoDUNE-HD detector-glitch data if that data becomes available.

Wilson, C. [Cincinnati U., RWC]↗

STANDARD REFERENCE MATERIAL CHARPY TESTING FROM HIGH FLUENCE SURVEILLANCE CAPSULE

The Palisades Nuclear Generating Station included in its original surveillance program a surveillance capsule, designated A-60. The capsule was removed from its surveillance position in early 1995 and has been resident in the spent fuel pool since that time. It was harvested to perform characterization of surveillance specimens in this capsule in 2023. This capsule was irradiated to a fluence of 1.96x1020 n/cm2 (E> 1MeV) that is equivalent for more than 150 effective full power years for the current US reactor pressure vessel (RPV) fleet. This capsule contained several materials, including Charpy specimens of standard reference material (SRM) from Heavy-Section Steel Technology (HSST) A533-B Plate 01. To perform Charpy testing of this highly irradiated material, the new Charpy specimen transfer system was designed and implemented on Charpy impact testing machine in the hot cell to accommodate remote testing of these specimens. This new transfer system includes integrated environmental chamber to cool or heat Charpy specimens to the desired temperature. Testing of this highly irradiated material revealed very large shift of Charpy transition temperature, 188oC.

Sokolov, Mikhail [ORNL] (ORCID:0000000256373346)↗

Generic Construction of the Standard Model Gauge Group and Matter Representations in F-theory

In this work, we describe general classes of 6D and 4D F-theory models with gauge group (SU(3)×SU(2)×U(1))/Z 6 . For 6D F-theory models with no tensor multiplets, we prove that this set of constructions gives all possible consistent supergravity theories with this gauge group and the corresponding generic matter representations, which include those of the MSSM. We expect, though do not prove, that these models are similarly generic for 6D theories with tensor multiplets and for 4D N=1 supergravity theories. Finally, the models in the largest class of these constructions come from deforming an underlying geometry with SU(4)×SU(3)×SU(2), corresponding to Higgsing on three bifundamental fields.

72 PHYSICS OF ELEMENTARY PARTICLES AND FIELDS↗