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At least 775 records · Page 43

Generating SBoMs Utilizing Structured Threat Information Expression JSON bundles

With cyber-attacks on the rise, information is one of the first lines of defense. Now more than ever, security experts and developers need efficient ways to know if their software may be outdated or vulnerable to emerging threats. By generating a Software Bill of Material based on STIX2/JSON bundles, security experts and developers can ensure that they know where to find what can go wrong with their systems before the hackers do. As part of the Infrastructure Expression project, Idaho National Laboratory (INL) is currently working on ways that can aid in the development of efficient SBOMs using Structured Threat Information Expression (STIX). Doing so can provide an efficient first line of defense for detection and monitoring that can be easily used by cyber personnel from beginners to highly skilled experts.

97 MATHEMATICS AND COMPUTING↗

An operator-based approach to topological photonics

Abstract Recently, the study of topological structures in photonics has garnered significant interest, as these systems can realize robust, nonreciprocal chiral edge states and cavity-like confined states that have applications in both linear and nonlinear devices. However, current band theoretic approaches to understanding topology in photonic systems yield fundamental limitations on the classes of structures that can be studied. Here, we develop a theoretical framework for assessing a photonic structure’s topology directly from its effective Hamiltonian and position operators, as expressed in real space, and without the need to calculate the system’s Bloch eigenstates or band structure. Using this framework, we show that nontrivial topology, and associated boundary-localized chiral resonances, can manifest in photonic crystals with broken time-reversal symmetry that lack a complete band gap, a result that may have implications for new topological laser designs. Finally, we use our operator-based framework to develop a novel class of invariants for topology stemming from a system’s crystalline symmetries, which allows for the prediction of robust localized states for creating waveguides and cavities.

97 MATHEMATICS AND COMPUTING↗

Meeting the Deadline: Why, When and How

A normative system is defined as any set of interacting agents whose behavior can usefully be regarded as norm-directed. Most organizations, and more specifically institutions, fall under this definition. Interactions in these normative systems are regulated by normative templates that describe desired behavior in terms of deontic concepts (obligations, prohibitions and permissions), deadlines, violations and sanctions. Agreements between agents, and between an agent and the society, can then be specified by means of contracts. Contracts provide flexible but verifiable means to integrate society requirements and agent autonomy. and are an adequate means for the explicit specification of interactions. From the society perspective, it is important that these contracts adhere to the specifications described in the model of the organization. If we want to automate such verifications, we have to formalize the languages used for contracts and for the specification of organizations. The logic LCR is based on deontic temporal logic. LCR is an expressive language for describing interaction in multi-agent systems, including obligations with deadlines. Deadlines are important norms in most interactions between agents. Intuitively, a deadline states that an agent should perform an action before a certain point in time. The obligation to perform the action starts at the moment the deadline becomes active. E.g. when a contract is signed or approved. If the action is not performed in time a violation of the deadline occurs. It can be specified independently what measure has to be taken in this case. In this paper we investigate the deadline concept in more detail. The paper is organized as follows. Section 2 defines the variant of CTL we use. In section 3, we discuss the basic intuitions of deadlines. Section 4 presents a first intuitive formalization for deadlines. In section 5, we look at a more complex model for deadlines trying to catch some more practical aspects. Finally, in section 6 we present issues for future work and our conciusions.

Dignum, Frank↗

An engineering optimization method with application to STOL-aircraft approach and landing trajectories

An optimization method has been developed that computes the optimal open loop inputs for a dynamical system by observing only its output. The method reduces to static optimization by expressing the inputs as series of functions with parameters to be optimized. Since the method is not concerned with the details of the dynamical system to be optimized, it works for both linear and nonlinear systems. The method and the application to optimizing longitudinal landing paths for a STOL aircraft with an augmented wing are discussed. Noise, fuel, time, and path deviation minimizations are considered with and without angle of attack, acceleration excursion, flight path, endpoint, and other constraints.

Jacob, H. G.↗

Identification and interpretation of tectonic features from ERTS-1 imagery: Southwestern North America and the Red Sea area

The author has identified the following significant results. The ERTS-1 imagery was utilized to study major fault and tectonic lines and their intersections in southwestern North America. A system of transverse shear faults was recognized in the California Coast Ranges, the Sierra Nevada, the Great Basin, and Mexico. They are interpreted as expressions of a major left-lateral shear which predated the San Andreas system, the opening of the Gulf of California and Basin and Range rift development. Tectonic models for Basin and Range, Coast Ranges, and Texas-Parras shears were developed. Geological structures and Precambrian metamorphic trend lines of schistosity were studied across the Red Sea rift.

Abdel-Gawad, M.↗

Propagation effects for land mobile satellite systems: Overview of experimental and modeling results

Models developed and experiments performed to characterize the propagation environment associated with land mobile communication using satellites are discussed. Experiments were carried out with transmitters on stratospheric balloons, remotely piloted aircraft, helicopters, and geostationary satellites. This text is comprised of compiled experimental results for the expressed use of communications engineers, designers of planned Land Mobile Satellite Systems (LMSS), and modelers of propagation effects. The results presented here are mostly derived from systematic studies of propagation effects for LMSS geometries in the United States associated with rural and suburban regions. Where applicable, the authors also draw liberally from the results of other related investigations in Canada, Europe, and Australia. Frequencies near 1500 MHz are emphasized to coincide with frequency bands allocated for LMSS by the International Telecommunication Union, although earlier experimental work at 870 MHz is also included.

Goldhirsh, Julius↗

Expressions Module for the Satellite Orbit Analysis Program

The Expressions Module is a software module that has been incorporated into the Satellite Orbit Analysis Program (SOAP). The module includes an expressions- parser submodule built on top of an analytical system, enabling the user to define logical and numerical variables and constants. The variables can capture output from SOAP orbital-prediction and geometric-engine computations. The module can combine variables and constants with built-in logical operators (such as Boolean AND, OR, and NOT), relational operators (such as >, <, or =), and mathematical operators (such as addition, subtraction, multiplication, division, modulus, exponentiation, differentiation, and integration). Parentheses can be used to specify precedence of operations. The module contains a library of mathematical functions and operations, including logarithms, trigonometric functions, Bessel functions, minimum/ maximum operations, and floating- point-to-integer conversions. The module supports combinations of time, distance, and angular units and has a dimensional- analysis component that checks for correct usage of units. A parser based on the Flex language and the Bison program looks for and indicates errors in syntax. SOAP expressions can be built using other expressions as arguments, thus enabling the user to build analytical trees. A graphical user interface facilitates use.

Edmonds, Karina↗

Stress from long-range interactions in particulate system

In particulate systems, the ensemble average accounting for effects from all particles is expressed as the expected value related to the nearest particle probability. Using this expression, a stress is defined even for long-range particle interactions without the divergence difficulty because of the rapid far field decay of the probability. Similar to the potential part of the virial stress in molecular systems, this stress represents particle-particle interactions through the surrounding field. As examples, the stresses are calculated for systems of charged particles and disperse multiphase flows.

97 MATHEMATICS AND COMPUTING↗

Bandwidth limitations on noiseless optical channel capacity

The channel capacity of an optical communications link utilizing direct photon detection can be substantially larger than the heterodyne detection quantum limit. In the limit of a noiseless channel the capacity per received photon can even be infinite. In most communications systems the real constraint is to deliver a certain throughput capacity measured in nats/second. The current investigation has the objective to show that due to physical limitations on the minimum time resolution which can be achieved, and for any given throughput capacity in nats/second, there exists an optimum PPM word size which maximizes the 'power efficiency capacity' expressed in nats/photon. Such an optimization will allow the system-designer to minimize the amount of power needed to achieve the desired throughput without violating his bandwidth constraint.

Butman, S. A.↗

YAP/STAT3 promotes the immune escape of larynx carcinoma by activating VEGFR1-TGFβ signaling to facilitate PD-L1 expression in M2-like TAMs

Larynx carcinoma (LC) is the most prevalent head and neck cancer among adults. LC xenograft mouse model was generated to verify the effect of VEGF on macrophage polarization and tumor growth in vivo. EdU assay was performed to measure the cell proliferation. Transwell assay was applied to assess cell migration. The expression of YAP and STAT3 was also significantly increased in LC tumor tissues. Moreover, both YAP and STAT3 overexpression in LC cells promoted the proliferation, migration, as well as the secretion of PD-L1 in M2-like TAMs. Mechanistically, the interaction between YAP and STAT3 facilitated the transcription of VEGF. Moreover, with a co-culture system, VEGF secretion in LC cells enhanced PD-L1 expression in M2-like TAMs via activating VEGFR1-TGFβ signaling pathway. Furthermore, VEGF secreted from LC cells also promoted the tumor growth of LC in vivo. We revealed that dysregulated YAP/STAT3 activity in LC cells could enhance the secretion of VEGF, which then functioned on M2-like TAMs via activating VEGFR1-TGFββ pathway to promote the expression of PD-L1 and immunosuppressive function of M2-like TAMs. Therefore, VEGF and PD-L1 might have a pivotal crosstalk between M2-like TAMs and LC cells, which provided a novel therapeutic target in regulating the metastasis of LC in future.

60 APPLIED LIFE SCIENCES↗

A computational procedure for multibody systems including flexible beam dynamics

A computational procedure suitable for the solution of equations of motions for flexible multibody systems has been developed. A fully nonlinear continuum approach capable of accounting for both finite rotations and large deformations has been used to model a flexible beam component. The beam kinematics are referred directly to an inertial reference frame such that the degrees of freedom embody both the rigid and flexible deformation motions. As such, the beam inertia expression is identical to that of rigid body dynamics. The nonlinear coupling between gross body motion and elastic deformation is contained in the internal force expression. Numerical solution procedures for the integration of spatial kinematic systems can be directily applied to the generalized coordinates of both the rigid and flexible components. An accurate computation of the internal force term which is invariant to rigid motions is incorporated into the general solution procedure.

Downer, J. D.↗

Auger spectroscopy beyond the ultra-short core-hole relaxation time approximation

Abstract We present a time-dependent computational approach to study Auger electron spectroscopy (AES) beyond the ultra-short core-hole relaxation time approximation and, as a test case, we apply it to the paradigmatic example of a one-dimensional Mott insulator represented by a half-filled Hubbard chain. The Auger spectrum is usually calculated by assuming that, after the creation of a core-hole, the system thermalizes almost instantaneously. This leads to a relatively simple analytical expression that uses the ground-state with a core-hole as a reference state and ignores all the transient dynamics related to the screening of the core-hole. In this picture, the response of the system can be associated to the pair spectral function. On the other hand, in our numerical calculations, the core hole is created by a light pulse, allowing one to study the transient dynamics of the system in terms of the pulse duration and in the non-perturbative regime. Time-dependent density matrix renormalization group calculations reveal that the relaxation process involves the creation of a polarization cloud of doublon excitations that have an effect similar to photo-doping. As a consequence, there is a leak of spectral weight to higher energies into what otherwise would be the Mott gap. For longer pulses, these excited states, mostly comprised of doublons, can dominate the spectrum. By changing the duration of the light-pulse, the entire screening process can be resolved in time.

75 CONDENSED MATTER PHYSICS, SUPERCONDUCTIVITY AND↗

Nonlinear transient analysis of multi-mass flexible rotors - theory and applications

The equations of motion necessary to compute the transient response of multi-mass flexible rotors are formulated to include unbalance, rotor acceleration, and flexible damped nonlinear bearing stations. A method of calculating the unbalance response of flexible rotors from a modified Myklestad-Prohl technique is discussed in connection with the method of solution for the transient response. Several special cases of simplified rotor-bearing systems are presented and analyzed for steady-state response, stability, and transient behavior. These simplified rotor models produce extensive design information necessary to insure stable performance to elastic mounted rotor-bearing systems under varying levels and forms of excitation. The nonlinear journal bearing force expressions derived from the short bearing approximation are utilized in the study of the stability and transient response of the floating bush squeeze damper support system. Both rigid and flexible rotor models are studied, and results indicate that the stability of flexible rotors supported by journal bearings can be greatly improved by the use of squeeze damper supports. Results from linearized stability studies of flexible rotors indicate that a tuned support system can greatly improve the performance of the units from the standpoint of unbalanced response and impact loading. Extensive stability and design charts may be readily produced for given rotor specifications by the computer codes presented in this analysis.

Kirk, R. G.↗

Static shape control for flexible structures

An integrated methodology is described for defining static shape control laws for large flexible structures. The techniques include modeling, identifying and estimating the control laws of distributed systems characterized in terms of infinite dimensional state and parameter spaces. The models are expressed as interconnected elliptic partial differential equations governing a range of static loads, with the capability of analyzing electromagnetic fields around antenna systems. A second-order analysis is carried out for statistical errors, and model parameters are determined by maximizing an appropriate defined likelihood functional which adjusts the model to observational data. The parameter estimates are derived from the conditional mean of the observational data, resulting in a least squares superposition of shape functions obtained from the structural model.

Rodriguez, G.↗

Inferring protein expression changes from mRNA in Alzheimer’s dementia using deep neural networks

Identifying the molecular systems and proteins that modify the progression of Alzheimer’s disease and related dementias (ADRD) is central to drug target selection. However, discordance between mRNA and protein abundance, and the scarcity of proteomic data, has limited our ability to advance candidate targets that are mainly based on gene expression. Therefore, by using a deep neural network that predicts protein abundance from mRNA expression, here we attempt to track the early protein drivers of ADRD. Specifically, by applying the clei2block deep learning model to 1192 brain RNA-seq samples, we identify protein modules and disease-associated expression changes that were not directly observed at the mRNA level. Moreover, pseudo-temporal trajectory inference based on the predicted proteome became more closely correlated with cognitive decline and hippocampal atrophy compared to RNA-based trajectories. This suggests that the predicted changes in protein expression could provide a better molecular representation of ADRD progression. Furthermore, overlaying clinical traits on protein pseudotime trajectory identifies protein modules altered before cognitive impairment. These results demonstrate how our method can be used to identify potential early protein drivers and possible drug targets for treating and/or preventing ADRD.

60 APPLIED LIFE SCIENCES↗

Optimal limited state variable feedback controllers for linear systems.

Optimized static and dynamic linear system compensator designs with a priori fixed dimensions are discussed. Expressions are derived to determine the parameters of these designs, including the fixed-gain output feedback, the time-varying output feedback, and time-invariant compensation. A relevant deterministic off-line optimization problem is formulated, and the properties of a solution to the problem are analyzed. A unified design philosophy for limited state-variable control problems of essentially deterministic systems is developed. The philosophy incorporates design constraints, a careful selection of performance criteria, and interpretation of the results.

Levine, W. S.↗

Principal axes and moments of inertia of deformable systems

Information about principal axes and moments of inertia is presented in terms of formulas involving solely quantities which can be expressed in literal form whenever central principal axes can be located by inspection for at least one state of a deformable system composed of particles and rigid bodies. Two illustrative examples are worked out in detail.

Kane, T. R.↗

Forbidden Mass Ranges for Shower Meteoroids

Burns et al. (1979) use the parameter beta to describe the ratio of radiation pressure to gravity for a particle in the Solar System. The central potential that these particles experience is effectively reduced by a factor of (1- beta ), which in turn lowers the escape velocity. Burns et al. (1979) derived a simple expression for the value of beta at which particles ejected from a comet follow parabolic orbits and thus leave the Solar System; we expand on this to derive an expression for critical beta values that takes ejection velocity into account, assuming geometric optics. We use our expression to compute the critical value and corresponding mass for cometary ejecta leading, trailing, and following the parent comet's nucleus for 10 major meteor showers. Finally, we numerically solve for critical beta values in the case of non-geometric optics. These values determine the mass regimes within which meteoroids are ejected from the Solar System and therefore cannot contribute to meteor showers.

Moorhead, Althea V.↗