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At least 757 records · Page 42

Bending Properties of Nickel Electrodes for Nickel-Hydrogen Batteries

Recent changes in manufacturing have resulted in nickel-hydrogen batteries that fail prematurely by electrical shorting, This failure is believed to be a result of a blistering problem in the nickel electrodes. In this study the bending properties of nickel electrodes are investigated in an attempt to correlate the bending properties of the electrode with its propensity to blister. Nickel electrodes from three different batches of material were tested in both the as-received and impregnated forms. The effects of specimen curvature and position within the electrode on the bending strength were studied, and within-electrode and batch-to-batch variations were addressed. Two color-imaging techniques were employed to differentiate between the phases within the electrodes. These techniques aided in distinguishing the relative amounts of nickel hyroxide surface loading on each electrode, thereby relating surface loading to bend strength. Bend strength was found to increase with the amount of surface loading.

Lerch, Brad A.↗

Transition Experiments on Blunt Bodies with Distributed Roughness in Hypersonic Free Flight in Carbon Dioxide

Blunt-body geometries were flown through carbon dioxide in the NASA Ames Hypervelocity Free Flight Aerodynamic Facility to investigate the influence of distributed surface roughness on transition to turbulence in CO2-dominated atmospheres, such as those of Mars and Venus. Tests were also performed in air for direct comparison with archival results. Models of hemispherical and spherically-blunted large-angle conical geometries were flown at speeds between 2.8 km/s and 5.1 km/s and freestream pressures between 50 Torr and 228 Torr. Transition fronts were determined from global surface heat flux distributions measured using thermal imaging techniques. Distributed surface roughness was produced by grit-blasting the model surfaces. Real-gas Navier-Stokes solutions were used to calculate non-dimensional correlating parameters at the measured transition onset locations. Transition-onset locations correlated well with a constant roughness Reynolds number based on the mean roughness element height. The critical roughness Reynolds number for transition onset determined for flight in CO2 was 223 +/- 25%. This mean value is lower than the critical value of 250 +/- 20% previously-established from tests conducted in air, but within the bounds of the expected measurement uncertainty.

ballistic ranges↗

Pilot Study on the Investigation of Tear Fluid Biomarkers as an Indicator of Ocular, Neurological, and Immunological Health in Astronauts

The purpose of this pilot study is to investigate the collection, preparation, and analysis of tear biomarkers as a means of assessing ocular, neurological, and immunological health. At present, no published data exists on the cytokine profiles of tears from astronauts exposed to long periods of microgravity and space irradiations. In addition, no published data exist on cytokine (biomarker) profiles of tears that have been collected from irradiated non-human biological systems (primates and other animal models). A goal for the proposed pilot study is to discover novel tear biomarkers which can help inform researchers, clinicians, epidemiologist and healthcare providers about the health status of a living biological system, as well as informing them when a disease state is triggered. This would be done via analysis of the onset of expression of pro-inflammatory cytokines, leading up to the full progression of a disease (i.e. cancer, loss of vision, radiation-induced oxidative stress, cardiovascular disorders, fibrosis in major organs, bone loss). Another goal of this pilot study is to investigate the state of disease against proposed medical countermeasures, in order to determine whether the countermeasures are efficacious in preventing or mitigating these injuries. An example of an up and coming tear biomarker technology, Ascendant Dx, a clinical stage diagnostic company, is developing a screening test to detect breast cancer using proteins from tears. The team utilized Liquid Chromatography -Mass Spectrometry with Mass analysis (LC MS/MS) as a discovery platform followed by validation with ELISA to come up with a panel of protein biomarkers that can differentiate breast cancer samples from control ("cancer free") samples with results far surpassing the results of imaging techniques in use today. Continued research into additional proteins is underway to increase the sensitivity and specificity of the test and development efforts are on the way to transfer the test onto a fast, accurate and inexpensive point of care platform. In conclusion, the expected results from this proposed pilot study are to: a) establish an SOP for retrieving/storing/transporting tear fluid samples from multicentre sites b) establish a normal range for relevant biomarkers in tears; and c) establish a database (biobank) of tears of space naïve versus veteran astronauts, to establish a personal baseline for long-term ocular health monitoring

Morton, Stephen↗

A Summary of Results from Two Full-Scale Fokker F28 Fuselage Section Drop Tests

During 2017, two vertical drop tests were conducted on two partial sections removed from a Fokker F28 MK4000 aircraft as a part of a joint NASA / Federal Aviation Administration (FAA) effort to investigate the crashworthiness characteristics of Transport Category Aircraft, as defined by 14 Code of Federal Regulations, Part 25. The first test was a pure vertical drop test of a relatively uniform forward section, which included an underfloor area for luggage. The second test was a canted drop test onto a sloped surface of a portion of the fuselage representing the wingbox stiffened structure. In both tests, accelerometers were installed on the floor, seat track, luggage, and overhead bin to measure responses in the two airframe sections. In addition, ten Anthropomorphic Test Devices (ATDs, a.k.a. crash test dummies) were included in each test to measure the potential of onboard occupant injury. Self-contained data recorders, logging accelerations and rotational rates, were also used on the seat tracks and lower structure for evaluation as potential crash recording devices in future tests. Finally, the starboard side of each section was painted with a stochastic black and white speckle pattern for use in full field photogrammetric imaging techniques. The results collected show notable differences in the Forward and Wingbox Section responses. The Forward Section floor accelerations showed a relatively uniform response of approximately 7 g throughout the impact event. This section exhibited large amounts of subfloor crushing, floor stiffener failures and seat deformation upon impact. These results are contrasted by the Wingbox Section accelerations, which showed large differences when comparing accelerations recorded from either the rear or the front portion of the section reaching peaks of 39 g in some locations. Additionally, the Wingbox Section test induced a forward motion caused from the rotation at impact. With the exception of the lower cavity, there was minimal deformation in the Wingbox Section, and ATD responses were consistently higher than those for the Forward Section. A complete set of results are presented for the airframe, seat, ATD, overhead bin, and subfloor regions for each section. The ATD results are compared to current injury criteria, and determinations will be made on the likelihood of injury. Additional results for cargo-hold stored luggage are presented in an attempt to provide a component-level characterization for better understanding of under-floor loading. Finally, a discussion of the relevance of the results for a proposed airframe level crashworthiness guideline are presented.

Littell, Justin D.↗

Full-Scale Drop Test of a Fokker F28 Wingbox Fuselage Section

During the summer of 2017, a vertical drop test was conducted on a partial section of a Fokker F28 MK4000 aircraft as a part of a joint NASA/FAA effort to investigate the performance of transport category aircraft under realistic crash conditions. Ten Anthropomorphic Test Devices (ATDs, a.k.a. crash test dummies) ranging from 5th to 95th percentile sizes were used for the collection and comparison of occupant loads. Additionally, overhead bin mass simulators were added to achieve a realistic fuselage configuration. The section was dropped with a downward facing pitch angle onto a sloping soil surface in order to simulate a local horizontal velocity in the airframe. Instrumentation consisting of accelerometers was installed to measure floor, seat track, ATD, and overhead bin acceleration responses. Self-contained data recorders logging accelerations and rotational rates were also used on the seat tracks and lower structure as evaluations for crash recording devices in potential future use cases. The right side of the section was painted with a stochastic black and white speckle pattern for use in full field photogrammetric imaging techniques. Results collected from the airframe accelerometers will be presented, and deformation and failures of the test article structure will be discussed. Finally, an examination of the test article motion will be presented using derived components of local velocities with their effect on the impact acceleration and airframe response.

Littell, J. D.↗

Observations of Fast-Moving Features in the Debris Disk of AU Mic on a Three-Year Timescale: Confirmation and New Discoveries

Context. The nearby and young M star AU Mic is surrounded by a debris disk in which we previously identified a series of large-scale arch-like structures that have never been seen before in any other debris disk and that move outward at high velocities. Aims. We initiated a monitoring program with the following objectives: (1) track the location of the structures and better constrain their projected speeds, (2) search for new features emerging closer in, and ultimately (3) understand the mechanism responsible for the motion and production of the disk features. Methods. AU Mic was observed at 11 different epochs between August 2014 and October 2017 with the IR camera and spectrograph of SPHERE. These high-contrast imaging data were processed with a variety of angular, spectral, and polarimetric differential imaging techniques to reveal the faintest structures in the disk. We measured the projected separations of the features in a systematic way for all epochs. We also applied the very same measurements to older observations from the Hubble Space Telescope (HST) with the visible cameras STIS and ACS. Results. The main outcomes of this work are (1) the recovery of the five southeastern broad arch-like structures we identified in our first study, and confirmation of their fast motion (projected speed in the range 4–12 km/s); (2) the confirmation that the very first structures observed in 2004 with ACS are indeed connected to those observed later with STIS and now SPHERE; (3) the discovery of two new very compact structures at the northwest side of the disk (at 0.40′′ and 0.55′′ in May 2015) that move to the southeast at low speed; and (4) the identification of a new arch-like structure that might be emerging at the southeast side at about 0.4′′ from the star (as of May 2016). Conclusions. Although the exquisite sensitivity of SPHERE allows one to follow the evolution not only of the projected separation, but also of the specific morphology of each individual feature, it remains difficult to distinguish between possible dynamical scenarios that may explain the observations. Understanding the exact origin of these features, the way they are generated, and their evolution over time is certainly a significant challenge in the context of planetary system formation around M stars.

Boccaletti, A.↗

New Technologies for Enabling Food Production Beyond LEO

NASA has identified the need for robust and sustainable ‘Pick-and-Eat’ systems for supplementing crew diets with fresh leafy green crops in near-term LEO (Low Earth Orbit), cislunar, and lunar missions. Spaceflight plant growth systems have been primarily designed for conducting space biology studies, but these systems are not optimal for sustained food production. Improved water and nutrient delivery subsystems that do not use bulky and non-reusable media are needed for decreasing the mass of the food production system. Autonomous technologies for monitoring plant health and food safety are needed for ensuring that the food produced is suitable supplementing crew diets with fresh, nutritious salad crops. Improved plant imaging techniques used for high-throughput phenotyping can be leveraged for monitoring plant health. Near-real-time measurements of the microbial ecology of food production systems are needed for assessing food safety. Furthermore, newly identified plant species and cultivars with improved growth habits and contents of antioxidants, vitamins, and minerals when grown in spaceflight environmental conditions are needed. These improvements in food production technologies will enable the design of sustainable life support systems for manned exploration missions beyond Low Earth Orbit.

Monje Mejia, Oscar A.↗

TPSAS-NF1676L-17553-DND

Investigate the potential of using an efficient damage imaging technique for damage identification by using a commercial finite element code to simulate the Lamb wave propagation in stiffened composite structures.

J T Wang↗

Below Band-Gap Laser Ablation of Diamond for Transmission Electron Microscopy

A 248-nm excimer laser was used to thin naturally occurring type 1a diamond substrates at normal and glancing (22 deg) incidence. Perforation of a 250 micron thick substrate was achieved in about 15 minutes at normal incidence. Whilst the substrate thinned at glancing incidence was found to have large electron-transparent areas, that thinned at normal incidence required additional argon milling to achieve electron transparency. X-ray photoelectron spectroscopy of the back surface of the diamond failed to detect any graphite or glassy carbon, confirming that damage due to laser ablation occurs only at the incident surface. Samples prepared using this technique imaged in the transmission electron microscope were observed to have retained the nitrogen platelets

Posthill, J. B.↗

Keck/OSIRIS Paβ High-contrast Imaging and Updated Constraints on PDS 70b

We present a high-contrast imaging search for Paβ line emission from protoplanets in the PDS 70 system with Keck/OSIRIS integral field spectroscopy. We applied the high-resolution spectral differential imaging technique to the OSIRIS J-band data but did not detect the Paβ line at the level predicted using the parameters of Hashimoto et al. (2020). This lack of Paβ emission suggests the MUSE-based study may have overestimated the line width of Hα. We compared our Paβ detection limits with the previous Hα flux and Hβ limits and estimated AV to be ∼0.9 and 2.0 for PDS 70 b and c, respectively. In particular, PDS 70 b’s AV is much smaller than implied by high-contrast near-infrared studies, which suggests the infrared-continuum photosphere and the hydrogen-emitting regions exist at different heights above the forming planet.

Taichi Uyama↗

Compact Midwave Imaging System: Results from an Airborne Demonstration

The Compact Midwave Imaging System (CMIS) is a wide field of view, multi-angle, multi-spectral push frame imager that relies on the forward motion of the satellite to create a two-dimensional (2D) image swath. An airborne demonstration of CMIS was successfully completed in January-February 2021 on the NASA Langley Research Center Gulfstream III. The primary objective of the four-flight campaign was to demonstrate the capability of this unique instrument to perform stereo observations of clouds and other particulates (e.g. smoke) in the atmosphere. It is shown that the midwave infrared (MWIR) spectral bands of CMIS provide a unique 24/7 capability with high resolution for accurate stereo sensing.The instrument relies on new focal plane array (FPA) technology, which provides excellent sensitivity at much warmer detector temperatures than traditional technologies. This capability enabled a compact, low-cost design that can provide atmospheric motion vectors and cloud heights to support requirements for atmospheric winds in the 2017-2027 Earth Science Decadal Survey. Applications include day/night observations of the planetary boundary layer, severe weather, and wildfires. A comparison with current space-based earth science instruments demonstrates that the SWIR/MWIR multi-spectral capability of CMIS is competitive with larger, more expensive instrumentation. Imagery obtained over a controlled burn and operating nuclear power plant demonstrated the sensitivity of the instrument to temperature variations. The system relies on a mature stereoscopic imaging technique applied to the same scene from two independent platforms to unambiguously retrieve atmospheric motion vectors (AMVs) with accurate height assignment.This capability has been successfully applied to geostationary and low-earth orbit satellites to achieve excellent accuracy. When applied to a ground-point validation case, the accuracy for the CMIS aircraft observations was 20 m and 0.3 m/s for cloud heights and motion vectors, respectively. This result was confirmed by a detailed error analysis with analytical and covariance models. The results for CMIS cases with under flights of Aeolus, CALIPSO and Aqua provided a good validation of expected accuracies. The paper also showed the feasibility of accommodating CMIS on CubeSats to enable multiple instruments to be flown in a leader-follower mode.

stereo winds↗

Design and Testing of a Device for Homogeneous Moon Dust Deposition on Test Articles/Systems

During this decade, NASA is charged to return humans to the surface of the Moon. One of the most challenging aspects to operating on the lunar surface is the regolith present, which is pervasive and damaging. To support systems design and validation for this environment, the handling and application of lunar simulants onto test articles or systems becomes important, albeit difficult. A device to apply the same amount of dust uniformly was developed in a previous study (Hollingsworth et al., 2006) but was only utilized with Mars dust simulant during that previous project. The current work provides evaluation of this device with multiple lunar simulants, each representing different composition as found at various locations on the Moon’s surface. Enhancements to the design and operation of the dust distributor are also described, along with a new digital imaging technique to calculate the percent surface coverage of the dust after deposition. The results support the use of the distributor and improved techniques to provide a uniform coating of dust on test articles and systems.

lunar↗

Design and Testing of a Device for Moon Dust Deposition on Test Articles/Systems

During this decade, NASA is charged to return humans to the surface of the Moon. One of the most challenging aspects to operating on the lunar surface is the regolith present, which is pervasive and damaging. To support systems design and validation for this environment, the handling and application of lunar simulants onto test articles or systems becomes important, albeit difficult. A device to apply the same amount of dust uniformly was developed in a previous study but was only utilized with Mars dust simulant during that previous project. The current work provides evaluation of this device with multiple lunar simulants, each representing different composition as found at various locations on the Moon’s surface. Enhancements to the design and operation of the dust distributor are also described, along with a new digital imaging technique to calculate the percent surface coverage of the dust after deposition. The results support the use of the distributor and improved techniques to provide a uniform coating of dust on test articles and systems.

Kathryn M Hurlbert↗

The Porous Microstructure Analysis (PuMA) software

The open-source Porous Microstructure Analysis (PuMA) software was implemented to offer an efficient framework for determining material characteristics from 3D microstructures. Its development was inspired by progress in X-ray microtomography, an imaging technology that captures the internal structure of materials in 3D, and even in a 4D temporal context. Over recent years, this method has transformed the domain of materials science due to its capability to non-destructively examine material microstructures while presenting digital data about their geometrical details. It has provided insights into materials relevant to several NASA missions, including heatshields, parachute fabrics, meteorites, and other advanced composites. PuMA, in its current version 3, delivers an array of features, spanning from basic geometric insights of a microstructure to intricate anisotropic thermo-elastic and chemical behavior. Specifically, the software evaluates morphological attributes (specific surface area, volume fractions, mean intercept lengths, orientation) and physical characteristics (conductivity, elasticity, permeability, and tortuosity). Additionally, it can model material degradation processes, such as oxidation and surface chemistry interactions. The software can generate synthetic microstructures, from straightforward geometrical designs to intricate woven and non-woven geometries. Coupling material generation and characterization enable parametric studies and sensitivity analysis to optimize the microstructural performance and inform design decisions and reliability assessment based on uncertainty quantification. A recent addition to PuMA includes the TomoSAM plugin, devised to incorporate the cutting-edge Segment Anything Model (SAM). SAM is a promptable deep learning model that can identify objects and create image masks in a zero-shot manner, based only on a few user clicks. The synergy between these tools aids in the segmentation of complex 3D datasets from tomography or other imaging techniques, which would otherwise require a laborious manual segmentation process.

Tomography↗

The Porous Microstructure Analysis (PuMA) software

The open-source Porous Microstructure Analysis (PuMA) software was created to offer an efficient framework for determining material properties from 3D microstructures. Its development was inspired by progress in X-ray microtomography, an imaging technology that captures the internal structure of materials in 3D, and even in a 4D temporal context. Over recent years, this method has transformed the domain of materials science due to its capability to non-destructively examine material microstructures while presenting digital data about their geometrical details. It has provided insights into materials relevant to several NASA missions, including heatshields, parachute fabrics, meteorites, and other advanced composites. PuMA, in its current version 3, delivers an array of features, spanning from basic geometric insights of a microstructure to intricate anisotropic thermo-elastic and chemical behavior. Specifically, the software evaluates morphological attributes (specific surface area, volume fractions, mean intercept lengths, orientation) and physical characteristics (conductivity, elasticity, permeability, and tortuosity). Additionally, it can model material degradation processes, such as oxidation and surface chemistry interactions. The software can generate synthetic microstructures, from straightforward geometrical designs to intricate woven and non-woven geometries. Coupling material generation and characterization enables parametric studies and sensitivity analysis to optimize the microstructural performance and inform design decisions and reliability assessment based on uncertainty quantification. A recent addition to PuMA includes the TomoSAM plugin, devised to incorporate the cutting-edge Segment Anything Model (SAM) into our image segmentation workflow. SAM is a promptable deep learning model that can identify objects and create image masks in a zero-shot manner, based only on a few user clicks. The synergy between these tools aids in the segmentation of complex 3D datasets from tomography and other imaging techniques, which would otherwise require a laborious manual segmentation process.

Tomography↗

PET imaging of zinc transport

A method for producing a solution including a positron emitting zinc cation of 63Zn, and the method comprises bombarding a solution target including 63 Cu with high energy protons to produce a solution including a positron emitting zinc cation. A method for detecting or ruling out Alzheimer's disease in a patient comprises administering to a patient a detectable amount of a compound including a positron emitting zinc cation, wherein the zinc cation is targeted to β-amyloid in the patient, and acquiring an image to detect the presence or absence of β-amyloid in the patient. A method for detecting or ruling out cancer in a patient comprises administering to a patient a detectable amount of a compound including a positron emitting zinc cation, wherein the zinc cation is targeted to tissue in the patient; and acquiring an image using a medical imaging technique to detect zinc distribution in tissue in the patient.

DeGrado, Timothy R.↗

Compositions for use in diagnosing and treating melanoma, including metastatic melanoma and methods related to same

The present invention is directed to novel non-invasive diagnostic tools/compounds comprising a cyclic peptide wherein the compound binds to a MSH receptor to image and treat cancers, especially, melanoma, including metastatic melanoma in vivo. The present invention represents a clear advance in the art which presently relies on tissue biopsy for diagnoses of these cancers. The novel imaging probes are capable of detecting cancerous melanoma cells, as well as their metastatic spread in tissues. This represents a quantum step forward in the diagnosis and treatment of melanoma, including metastatic melanoma using non-invasive molecular imaging techniques. The novel probes of the present invention will also be useful to initiate therapy for melanoma as well as monitor patients response to chemotherapy treatments and other interventions or therapies used in the treatment of melanoma/metastatic melanoma. Compounds according to the present invention may be used as diagnostic tools for a number of conditions and diseases states as well as therapeutic agents for treating such conditions and disease states.

Miao, Yubin↗

Indigenous Organic Molecular Biosignatures are Detectable via ToF-SIMS of a Kerogen-rich Jurassic Clay

Time of Flight - Secondary Ion Mass Spectrometry (ToF-SIMS) is a Mass Spectrometry (MS) imaging technique that can be used in conjunction with traditional organic geochemical analysis (organics extracted from a crushed sample) in order to determine how molecules observed in the organic extracts were incorporated into a particular rock sample. This type of analysis may be used on samples collected as part of Mars Sample Return (MSR) in order to determine if potential organic compounds were indigenous to Mars or whether they are contaminants.Here we show that Organic Molecular Biosignatures (OMBs including steranes and derivatives of a carotenoid) are detectable via ToF-SIMS within a Jurassic mudstone. The OMBs are only detectable in areas with high organic carbon, likely kerogen, indicating that they are indigenous to the rock. We conclude that: I) Indigenous OMBs are detectable via ToF-SIMS in ancient, kerogen-rich samples; II) the presence of a molecular ion strengthens the interpretation of ToF-SIMS spectra of complex natural material, and III) the spatial co-occurrence of kerogen and potentially indigenous OMBs in ancient sediments is a valid test of their character. These conclusions are directly relevant to MSR sample selection as well as the analysis of MSR samples upon return.

Pasterski, Michael↗