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Search indexed NASA NTRS and DOE OSTI research on propulsion, heat transfer, battery materials and energy systems. Follow report and document links to the original sources.

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At least 739 records · Page 41

FM receiver dynamic response

Dynamic response of frequency modulation radio receiver employing amplitude sensitive discriminator

FREQUENCY MODULATION↗

Classification image weights and internal noise level estimation

For the linear discrimination of two stimuli in white Gaussian noise in the presence of internal noise, a method is described for estimating linear classification weights from the sum of noise images segregated by stimulus and response. The recommended method for combining the two response images for the same stimulus is to difference the average images. Weights are derived for combining images over stimuli and observers. Methods for estimating the level of internal noise are described with emphasis on the case of repeated presentations of the same noise sample. Simple tests for particular hypotheses about the weights are shown based on observer agreement with a noiseless version of the hypothesis.

Pattern Recognition, Visual/physiology↗

Plasma membrane ordering agent pluronic F-68 (PF-68) reduces neurotransmitter uptake and release and produces learning and memory deficits in rats

A substantial body of evidence indicates that aged-related changes in the fluidity and lipid composition of the plasma membrane contribute to cellular dysfunction in humans and other mammalian species. In the CNS, reductions in neuronal plasma membrane order (PMO) (i.e., increased plasma membrane fluidity) have been attributed to age as well as the presence of the beta-amyloid peptide-25-35, known to play an important role in the neuropathology of Alzheimer's disease (AD). These PMO increases may influence neurotransmitter synthesis, receptor binding, and second messenger systems as well as signal transduction pathways. The effects of neuronal PMO on learning and memory processes have not been adequately investigated, however. Based on the hypothesis that an increase in PMO may alter a number of aspects of synaptic transmission, we investigated several neurochemical and behavioral effects of the membrane ordering agent, PF-68. In cell culture, PF-68 (nmoles/mg SDS extractable protein) reduced [3H]norepinephrine (NE) uptake into differentiated PC-12 cells as well as reduced nicotine stimulated [3H]NE release. The compound (800-2400 microg/kg, i.p., resulting in nmoles/mg SDS extractable protein in the brain) decreased step-through latencies and increased the frequencies of crossing into the unsafe side of the chamber in inhibitory avoidance training. In the Morris water maze, PF-68 increased the latencies and swim distances required to locate a hidden platform and reduced the time spent and distance swam in the previous target quadrant during transfer (probe) trials. PF-68 did not impair performance of a well-learned working memory task, the rat delayed stimulus discrimination task (DSDT), however. Studies with 14C-labeled PF-68 indicated that significant (pmoles/mg wet tissue) levels of the compound entered the brain from peripheral (i.p.) injection. No PF-68 related changes were observed in swim speeds or in visual acuity tests in water maze experiments, rotorod performance, or in tests of general locomotor activity. Furthermore, latencies to select a lever in the DSDT were not affected. These results suggest that PF-68 induced deficits in learning and memory without confounding peripheral motor, sensory, or motivational effects at the tested doses. Furthermore, none of the doses induced a conditioned taste aversion to a novel 0.1% saccharin solution indicating a lack of nausea or gastrointestinal malaise induced by the compound. The data indicate that increases in neuronal plasma membrane order may have significant effects on neurotransmitter function as well as learning and memory processes. Furthermore, compounds such as PF-68 may also offer novel tools for studying the role of neuronal PMO in mnemonic processes and changes in PMO resulting from age-related disorders such as AD.

Poloxamer/pharmacology↗

Hierarchical motion organization in random dot configurations

Motion organization has 2 aspects: the extraction of a (moving) frame of reference and the hierarchical organization of moving elements within the reference frame. Using a discrimination of relative motions task, the authors found large differences between different types of motion (translation, divergence, and rotation) in the degree to which each can serve as a moving frame of reference. Translation and divergence are superior to rotation. There are, however, situations in which rotation can serve as a reference frame. This is due to the presence of a second factor, structural invariants (SIs). SIs are spatial relationships persisting among the elements within a configuration such as a collinearity among points or one point coinciding with the center of rotation for another (invariant radius). The combined effect of these 2 factors--motion type and SIs-influences perceptual motion organization.

NASA Discipline Space Human Factors↗

Robust pupil center detection using a curvature algorithm

Determining the pupil center is fundamental for calculating eye orientation in video-based systems. Existing techniques are error prone and not robust because eyelids, eyelashes, corneal reflections or shadows in many instances occlude the pupil. We have developed a new algorithm which utilizes curvature characteristics of the pupil boundary to eliminate these artifacts. Pupil center is computed based solely on points related to the pupil boundary. For each boundary point, a curvature value is computed. Occlusion of the boundary induces characteristic peaks in the curvature function. Curvature values for normal pupil sizes were determined and a threshold was found which together with heuristics discriminated normal from abnormal curvature. Remaining boundary points were fit with an ellipse using a least squares error criterion. The center of the ellipse is an estimate of the pupil center. This technique is robust and accurately estimates pupil center with less than 40% of the pupil boundary points visible.

Non-NASA Center↗

Practical Methods for Estimating Software Systems Fault Content and Location

Over the past several years, we have developed techniques to discriminate between fault-prone software modules and those that are not, to estimate a software system's residual fault content, to identify those portions of a software system having the highest estimated number of faults, and to estimate the effects of requirements changes on software quality.

fault-prone discriminant function↗

(abstract) A High Throughput 3-D Inner Product Processor

A particularily challenging image processing application is the real time scene acquisition and object discrimination. It requires spatio-temporal recognition of point and resolved objects at high speeds with parallel processing algorithms. Neural network paradigms provide fine grain parallism and, when implemented in hardware, offer orders of magnitude speed up. However, neural networks implemented on a VLSI chip are planer architectures capable of efficient processing of linear vector signals rather than 2-D images. Therefore, for processing of images, a 3-D stack of neural-net ICs receiving planar inputs and consuming minimal power are required. Details of the circuits with chip architectures will be described with need to develop ultralow-power electronics. Further, use of the architecture in a system for high-speed processing will be illustrated.

imaging parallel processing algorithms linear vect↗

Detector research

Pulse shape discrimination circuitry for dual crystal scintillation detector - Compton reduction

SCINTILLATION↗

Electronic circuit delivers pulse of high interval stability

Circuit generates a pulse of high interval stability with a complexity level considerably below systems of comparable stability. This circuit is being used as a linear frequency discriminator in the signal conditioner of the Apollo command module.

Fisher, B.↗