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At least 739 records · Page 41

Space travel directly induces skeletal muscle atrophy

Space travel causes rapid and pronounced skeletal muscle wasting in humans that reduces their long-term flight capabilities. To develop effective countermeasures, the basis of this atrophy needs to be better understood. Space travel may cause muscle atrophy indirectly by altering circulating levels of factors such as growth hormone, glucocorticoids, and anabolic steroids and/or by a direct effect on the muscle fibers themselves. To determine whether skeletal muscle cells are directly affected by space travel, tissue-cultured avian skeletal muscle cells were tissue engineered into bioartificial muscles and flown in perfusion bioreactors for 9 to 10 days aboard the Space Transportation System (STS, i.e., Space Shuttle). Significant muscle fiber atrophy occurred due to a decrease in protein synthesis rates without alterations in protein degradation. Return of the muscle cells to Earth stimulated protein synthesis rates of both muscle-specific and extracellular matrix proteins relative to ground controls. These results show for the first time that skeletal muscle fibers are directly responsive to space travel and should be a target for countermeasure development.

NASA Discipline Musculoskeletal↗

On the generation of a bubbly universe - A quantitative assessment of the CfA slice

A first attempt is made to calculate the properties of the matter distribution in a universe filled with overlapping bubbles produced by multiple explosions. Each spherical shell follows the cosmological Sedov-Taylor solution until it encounters another shell. Thereafter, mergers are allowed to occur in pairs on the basis of N-body results. At the final epoch, the matrix of overlapping shells is populated with 'galaxies' and the properties of slices through the numerically constructed cube compare well with CfA survey results for specified initial conditions. A statistic is found which measures the distance distribution from uniformly distributed points to the nearest galaxies on the projected plane which appears to provide a good measure of the bubbly character of the galaxy distribution. In a quantitative analysis of the CfA 'slice of the universe', a very good match is found between simulation and the real data for final average bubble radii of (13.5 + or - 1.5)/h Mpc with formal filling factor 1.0-1.5 or actual filling factor of 65-80 percent.

Ostriker, J. P.↗

Collisional excitation of formaldehyde in 'hot' interstellar molecular regions

Earlier calculations for rotational excitation of formaldehyde by collisions with He atoms are extended to include the lowest 81 rotational levels and kinetic temperatures to 300 K. Calculations are generally based on Green et al. (1978) but coupled differential equations are solved via a modified log-derivative propagator at low energies (Manolopoulos, 1986) and an R-matrix propagator at higher energies (Stechel, Walker, and Light, 1978). Consideration is given to the expected accuracy of the rates for excitation of formaldehyde by collisions with He atoms which are calculated in the present paper and to the expected differences between these rates and those for excitation by H2 molecules which comprise a larger fraction of the interstellar gas. The comparisons performed indicate that, for excitation by He, calculated state-to-state rates are likely to be 50 percent accurate, and total excitation rates, better than 20 percent. For excitation by H2, the rates should be increased by a factor of 2.2.

Green, Sheldon↗

Effect of Environment on Fatigue Behavior of a Nicalon(TM)/Si-N-C Ceramic Matrix Composite

The effect of environmental exposure on the fatigue life of Nicalon(TM) /Si-N-C composite was investigated in this study. Test specimens with arrays of 1.8 mm diameter holes and two different open areas, 25 and 35%, were machined. Three environmental conditions were studied: 1) continuous fatigue cycling in air, 2) fatigue cycling in air alternating with humidity exposure, and 3) fatigue cycling in air alternating with exposure to a salt-fog environment. All fatigue testing on specimens with holes was performed with a load ratio, R = 0.05, and at a temperature of 910 C. In general, fatigue lives were shortest for specimens subjected to salt-fog exposure and longest for specimens subjected to continuous fatigue cycling in air. The fatigue data generated on the specimens with holes were compared with fatigue data generated in air on specimens with no holes. Fatigue strength reduction factors for different environmental conditions and open areas investigated in the study were calculated for the Nicalon(TM) /Si-N-C composite.

Kalluri, Sreeramesh↗

Acousto-ultrasonic evaluation of ceramic matrix composite materials

Acousto-ultrasonic nondestructive evaluation of ceramic composite specimens with a lithium-alumino-silicate glass matrix reinforced with unidirectional silicon carbide (NICALON) fibers was conducted to evaluate their reserve of strength. Ceramic composite specimens with different amount of damage were prepared by four-point cyclic fatigue loading of the specimens at 500 C for a different number of cycles. The reserve of strength of the specimens was measured as the maximum bending stress recorded during four-pointed bending test with the load monotonically increased until failure occurs. It was observed that the reserve of strength did not correlate with the number of fatigue cycles. However, it was also observed that higher values of the stress wave factor measurements correspond to higher values of the reserve of strength test data. Therefore, these results show that the acousto-ultrasonic approach has the potential of being used to monitor damage and to estimate the reserve of strength of ceramic composites.

Dosreis, Henrique L. M.↗

NDE of titanium alloy MMC rings for gas turbine engines

Progress in the processing and fabrication of metal matrix composites (MMC's) requires appropriate mechanical and nondestructive testing methods. These methods are needed to characterize properties, assess integrity, and predict the life of engine components such as compressor rotors, blades, and vanes. Capabilities and limitations of several state-of-the-art nondestructive evaluation (NDE) technologies are investigated for characterizing titanium MMC rings for gas turbine engines. The use of NDE technologies such as x-ray computed tomography, radiography, and ultrasonics in identifying fabrication-related problems that caused defects in components is examined. Acousto-ultrasonics was explored to assess degradation of material mechanical properties by using stress wave factor and ultrasonic velocity measurements before and after the burst testing of the rings.

Baaklini, George Y.↗

Microstructurally based variations on the dwell fatgue life of titanium alloy IMI 834

An experimental study was undertaken to determine the role of microstructure on the fatigue life reduction observed in titanium alloy IMI 834 under dwell loading conditions. The wave forms compared were a trapezoid with 15 and 30 second hold times at the maximum test load and a baseline, 10 Hertz, haversine. The stress ratio for both loading wave forms was 0.10. The fatigue loading of each specimen was conducted in a vacuum within a scanning electron microscope chamber which minimized the possibility that the laboratory environment would adversely affect the material behavior. Two microstructural conditions were investigated in the experimental program. The first involved standard 'disk' material with equiaxed alpha in a transformed beta matrix. The second material was cut from the same disk forging as the first but was heat treated to obtain a martensitic alpha prime microstructure. Tensile tests were performed prior to the onset of the fatigue loading portion of the study, and it was determined that the yield strengths of the specimens from both material conditions were within ten percent. The maximum fatigue loads were chosen to be 72 percent of the average yield strength for both materials as determined from the tensile tests. It was found that the cycles to failure from the 10 Hertz loading wave form were reduced by a factor of approximately five when the loading was changed to the trapezoidal wave form for the standard 'disk' material. The fatigue life reduction for the martensitic structure under identical test conditions was approximately 1.75. The improvement observed with the martensitic structure also was accompanied by an increase in overall fatigue life for the wave forms tested. This paper will review the results and conclusions of this effort.

Thomsen, Mark L.↗

Surface analyses of composites exposed to the space environment on LDEF

We have conducted a series of surface analyses on carbon fiber/polyarylacetylene matrix composites that were exposed to the space environment on the LDEF satellite. None of the composites were catastrophically damaged by nearly six years of exposure to the space environment. Composites on the leading edge exhibited about 5 mils of surface erosion, but trailing edge panels exhibited no physical appearance changes due to exposure. Scanning electron microscopy (SEM) was used to show that the erosion morphology on the leading edge samples was dominated by crevasses parallel to the fibers with triangular cross sections 10 to 100 microns in depth. The edges of the crevasses were well defined and penetrated through both matrix and fiber. The data suggest that the carbon fibers are playing a significant role in crevasse initiation and/or enlargement, and in the overall erosion rate of the composite. X-ray photoelectron spectroscopy (XPS) and energy dispersive X-ray spectroscopy (EDS) results showed the presence of silicone and hydrocarbon contamination from in-flight sources. The role of contamination in crevasse initiation and enlargement is unknown at this time. These LDEF results demonstrate that the prediction of long term atomic oxygen erosion morphology for composite materials from erosion data obtained on short Space Shuttle missions is difficult. A better understanding of other factors such as thermal cycling and UV exposure which may influence erosion is necessary to improve the accuracy of the predictions.

Mallon, Joseph J.↗

A comparison of various micromechanics models for metal matrix composites

Four micromechanics models currently used in the analysis of metal matrix composites are reviewed. The four models are the vanishing fiber diameter model, the Aboudi model, the multicell model, and discrete fiber-matrix model. Results predicted by computer programs based on each of the models are compared. Comparisons are made for the laminate properties and laminate stress-strain behavior for boron/aluminum and silicon-carbide/titanium composites. The predictions of constituent stresses are also compared. The predictions are compared to experimental data. Each of the models did a reasonably good job predicting laminate properties and stress-strain behavior. Thus, the discriminator between the models is a question of what type of results are required, the capabilities of the model and program, or the ease of operation. The choice of a model and program depends on several factors and the same program may not be the best choice for all analysis needs. The descriptions and comparisons made in this paper should aid in the choice of a model and program.

Bigelow, C. A.↗

Models of polarized infrared emission from bipolar nebulae

Many stars with circumstellar dust shells show a high degree of linear polarization (Sato et al. 1985). We are developing a model which assumes that the polarization arises from scattering by circumstellar dust. Our model assumes a geometry in which the star is surrounded by an optically thin spherical dust shell and embedded within an optically thick disk. This geometry is consistent with that proposed for objects with bipolar molecular outflow. This is important because many bipolar flow objects have also been observed to be highly polarized. The high degree of linear polarization is produced because the disk differentially attenuates the light from the star. The light incident from the point source is attenuated by a factor of exp(-tau/cos theta) where theta is the angle between a ray from the point source to the scatterer and a ray normal to the disk; tau is the optical depth at the wavelength of interest. Hence, the light scattered from the regions directly above and below the disk give the largest contribution to the total flux. The scattering angle for light from these regions is near 90 deg., so the light is strongly polarized and, in the Rayleigh scattering regime, is polarized parallel to the disk. The Stokes parameters for the scattered light from each particle in the shell are calculated by using the scattering matrix elements generated by a Mie scattering program. After the Stokes parameters for each particle are computed they are summed to give the Stokes parameters for the entire shell. Two graphs are presented which show the intensity and polarization spectrum generated by our model using the optical constants for astronomical silicates as defined by Draine and Lee (1984).

Burns, M. S.↗

The ATIC Long Duration Balloon Project

Long Duration Balloon (LDB) scientific experiments, launched to circumnavigate the south pole over Antarctica, have particular advantages compared to Shuttle or other Low Earth Orbit (LEO) missions in terms of cost, weight, scientific 'duty factor' and work force development. The Advanced Thin Ionization Calorimeter (ATIC) cosmic ray astrophysics experiment is a good example of a university-based project that takes full advantage of current LDB capability. The ATIC experiment is currently being prepared for its first LDB science flight that will investigate the charge composition and energy spectra of primary cosmic rays over the energy range from about 10(exp 10) to 10(exp 14) eV. The instrument is built around a fully active, Bismuth Germanate (BGO) ionization calorimeter to measure the energy deposited by the cascades formed by particles interacting in a thick carbon target. A highly segmented silicon matrix, located above the target, provides good incident charge resolution plus rejection of the 'backscattered' particles from the interaction. Trajectory reconstruction is based on the cascade profile in the BGO calorimeter, plus information from the three pairs of scintillator hodoscope layers in the target section above it. A full evaluation of the experiment was performed during a test flight occurring between 28 December 2000 and 13 January 2001 where ATIC was carried to an altitude of approx. 37 km above Antarctica by an approx. 850,000 cu m helium filled balloon for one circumnavigation of the continent. All systems behaved well, the detectors performed as expected, more than 43 gigabytes of engineering and cosmic ray event data was returned and these data are now undergoing preliminary data analysis. During the coming 2002-2003 Antarctica summer season, we are preparing for a ATIC science flight with approx. 15 to 30 days of continuous data collection in the near-space environment of LDB float altitudes.

Guzik, T. G.↗

On polynomial preconditioning for indefinite Hermitian matrices

The minimal residual method is studied combined with polynomial preconditioning for solving large linear systems (Ax = b) with indefinite Hermitian coefficient matrices (A). The standard approach for choosing the polynomial preconditioners leads to preconditioned systems which are positive definite. Here, a different strategy is studied which leaves the preconditioned coefficient matrix indefinite. More precisely, the polynomial preconditioner is designed to cluster the positive, resp. negative eigenvalues of A around 1, resp. around some negative constant. In particular, it is shown that such indefinite polynomial preconditioners can be obtained as the optimal solutions of a certain two parameter family of Chebyshev approximation problems. Some basic results are established for these approximation problems and a Remez type algorithm is sketched for their numerical solution. The problem of selecting the parameters such that the resulting indefinite polynomial preconditioners speeds up the convergence of minimal residual method optimally is also addressed. An approach is proposed based on the concept of asymptotic convergence factors. Finally, some numerical examples of indefinite polynomial preconditioners are given.

Freund, Roland W.↗

Errors induced by the neglect of polarization in radiance calculations for Rayleigh-scattering atmospheres

Although neglecting polarization and replacing the rigorous vector radiative transfer equation by its approximate scalar counterpart has no physical background, it is a widely used simplification when the incident light is unpolarized and only the intensity of the reflected light is to be computed. We employ accurate vector and scalar multiple-scattering calculations to perform a systematic study of the errors induced by the neglect of polarization in radiance calculations for a homogeneous, plane-parallel Rayleigh-scattering atmosphere (with and without depolarization) above a Lambertian surface. Specifically, we calculate percent errors in the reflected intensity for various directions of light incidence and reflection, optical thicknesses of the atmosphere, single-scattering albedos, depolarization factors, and surface albedos. The numerical data displayed can be used to decide whether or not the scalar approximation may be employed depending on the parameters of the problem. We show that the errors decrease with increasing depolarization factor and/or increasing surface albedo. For conservative or nearly conservative scattering and small surface albedos, the errors are maximum at optical thicknesses of about 1. The calculated errors may be too large for some practical applications, and, therefore, rigorous vector calculations should be employed whenever possible. However, if approximate scalar calculations are used, we recommend to avoid geometries involving phase angles equal or close to 0 deg and 90 deg, where the errors are especially significant. We propose a theoretical explanation of the large vector/scalar differences in the case of Rayleigh scattering. According to this explanation, the differences are caused by the particular structure of the Rayleigh scattering matrix and come from lower-order (except first-order) light scattering paths involving right scattering angles and right-angle rotations of the scattering plane.

Mishchenko, M. I.↗

Methodology for Sensitivity Analysis, Approximate Analysis, and Design Optimization in CFD for Multidisciplinary Applications

An incremental iterative formulation together with the well-known spatially split approximate-factorization algorithm, is presented for solving the large, sparse systems of linear equations that are associated with aerodynamic sensitivity analysis. This formulation is also known as the 'delta' or 'correction' form. For the smaller two dimensional problems, a direct method can be applied to solve these linear equations in either the standard or the incremental form, in which case the two are equivalent. However, iterative methods are needed for larger two-dimensional and three dimensional applications because direct methods require more computer memory than is currently available. Iterative methods for solving these equations in the standard form are generally unsatisfactory due to an ill-conditioned coefficient matrix; this problem is overcome when these equations are cast in the incremental form. The methodology is successfully implemented and tested using an upwind cell-centered finite-volume formulation applied in two dimensions to the thin-layer Navier-Stokes equations for external flow over an airfoil. In three dimensions this methodology is demonstrated with a marching-solution algorithm for the Euler equations to calculate supersonic flow over the High-Speed Civil Transport configuration (HSCT 24E). The sensitivity derivatives obtained with the incremental iterative method from a marching Euler code are used in a design-improvement study of the HSCT configuration that involves thickness. camber, and planform design variables.

Taylor, Arthur C., III↗

Programmable display pushbuttons on the Space Station's telerobot control panel

The Man-Systems Telerobotics Laboratory at NASA's Johnson Space Center and supported by Lockheed, is working to ensure that the Flight Telerobotic Servicer (FTS) to be used on the Space Shuttle (Orbiter) and the Space Station has a well designed user interface from a Human Factors perspective. The FTS, which is a project led by NASA's Goddard Space Flight Center, will be a telerobot used for Space Station construction, maintenance, and satellite repair. It will be directly controlled from workstations on the Orbiter and the Space Station and monitored from a ground workstation. The FTS will eventually evolve into a more autonomous system, but in the short-term the system will be manually operated (teleoperated) for many tasks. This emphasizes the importance of the human/telerobot interface on this system. This phase of the FTS workstation evaluation covers a preliminary study of programmable display pushbuttons (PDP's). The PDP is constructed of a matrix of directly addressable electroluminescent (EL) pixels which can be used to form dot-matrix characters. PDP's can be used to display more than one message and to control more than one function. Since the PDP's have these features, then a single PDP may possibly replace the use of many single-function pushbuttons, rotary switches, and toggle switches, thus using less panel space. It is of interest to determine if PDP's can be used to adequately perform complex hierarchically structured task sequences. The objective of this investigation was to compare the performance of experienced and inexperienced Remote Manipulator System (RMS) operators while performing an RMS like task on simulated PDP and non-PDP computer prototypes so that guidelines governing the use of programmable display pushbuttons on the FTS workstation could be created. The functionality of the RMS on the Orbiter was used as a model for this evaluation since the functionality of the FTS at the time of this writing has not been solidified.

Stuart, Mark A.↗

Modulation of lens cell adhesion molecules by particle beams

Cell adhesion molecules (CAMs) are proteins which anchor cells to each other and to the extracellular matrix (ECM), but whose functions also include signal transduction, differentiation, and apoptosis. We are testing a hypothesis that particle radiations modulate CAM expression and this contributes to radiation-induced lens opacification. We observed dose-dependent changes in the expression of beta 1-integrin and ICAM-1 in exponentially-growing and confluent cells of a differentiating human lens epithelial cell model after exposure to particle beams. Human lens epithelial (HLE) cells, less than 10 passages after their initial culture from fetal tissue, were grown on bovine corneal endothelial cell-derived ECM in medium containing 15% fetal bovine serum and supplemented with 5 ng/ml basic fibroblast growth factor (FGF-2). Multiple cell populations at three different stages of differentiation were prepared for experiment: cells in exponential growth, and cells at 5 and 10 days post-confluence. The differentiation status of cells was characterized morphologically by digital image analysis, and biochemically by Western blotting using lens epithelial and fiber cell-specific markers. Cultures were irradiated with single doses (4, 8 or 12 Gy) of 55 MeV protons and, along with unirradiated control samples, were fixed using -20 degrees C methanol at 6 hours after exposure. Replicate experiments and similar experiments with helium ions are in progress. The intracellular localization of beta 1-integrin and ICAM-1 was detected by immunofluorescence using monoclonal antibodies specific for each CAM. Cells known to express each CAM were also processed as positive controls. Both exponentially-growing and confluent, differentiating cells demonstrated a dramatic proton-dose-dependent modulation (upregulation for exponential cells, downregulation for confluent cells) and a change in the intracellular distribution of the beta 1-integrin, compared to unirradiated controls. In contrast, there was a dose-dependent increase in ICAM-1 immunofluorescence in confluent, but not exponentially-growing cells. These results suggest that proton irradiation downregulates beta 1-integrin and upregulates ICAM-1, potentially contributing to cell death or to aberrant differentiation via modulation of anchorage and/or signal transduction functions. Quantification of the expression levels of the CAMs by Western analysis is in progress.

NASA Discipline Radiation Health↗

TURBOMAT: A Probabilistic Turbomachinery Aeroelastic Analysis Tool

An integration of aeroelastic analysis procedures with probabilistic analysis methods enables us to design safe reliable engines with quantified reliability. Towards this goal, a graphical user interface (GUI) based tool that integrates the codes Aeroelastic analysis of propfans (ASTROP2) and Numerical Evaluation of Stochastic Structures Under Stress (NESSUS) is developed. The tool entitled TURBOMachinery Aeroelastic Analysis Tool (TURBOMAT), is developed utilizing the MATrix Laboratory (Matlab) Guide (Graphical User Interface Development) tool box. TURBOMAT provides a user friendly computational environment for rapid assessment of Turbomachinery blades flutter characteristics, subjected to uncertain loading conditions with variability in material and aerodynamic properties. The tool is seen as an education tool for new students and young engineers starting their careers in structural Aeroelasticity who want to learn and understand aeroelastic aspects of turbomachinery components, fans, compressors and turbines, including uncertainties in loading and material properties.A typical fan blade configuration geometry was chosen to demonstrate the tool. The results are presented in the form of probabilistic density function (PDF), the cumulative distribution function (CDF) and sensitivity factors. Both first order fast probability integration (FPI) and the Monto Carlo (MC) techniques are used in the analysis and compared. The tool enabled us to quantify blade flutter reliability as well as the ranking of uncertain variables and their importance to blade flutter response.

Aeroelastic Analysis↗

Creep Properties of NiAl-1Hf Single Crystals Re-Investigated

NiAl-1Hf single crystals have been shown to be quite strong at 1027 C, with strength levels approaching those of advanced Ni-based superalloys. Initial testing, however, indicated that the properties might not be reproducible. Study of the 1027 C creep behavior of four different NiAl-1Hf single-crystal ingots subjected to several different heat treatments indicated that strength lies in a narrow band. Thus, we concluded that the mechanical properties are reproducible. Recent investigations of the intermetallic NiAl have confirmed that minor alloying additions combined with single-crystal growth technology can produce elevated temperature strength levels approaching those of Ni-based superalloys. For example, General Electric alloy AFN 12 {Ni-48.5(at.%) Al-0.5Hf-1Ti-0.05Ga} has a creep rupture strength equivalent to Rene 80 combined with a approximately 30-percent lower density, a fourfold improvement in thermal conductivity, and the ability to form a self-protective alumina scale in aggressive environments. Although the compositions of strong NiAl single crystals are relatively simple, the microstructures are complex and vary with the heat treatment and with small ingot-toingot variations in the alloy chemistry. In addition, initial testing suggested a strong dependence between microstructure and creep strength. If these observations were true, the ability to utilize NiAl single-crystal rotating components in turbine machinery could be severely limited. To investigate the possible limitations in the creep response of high-strength NiAl single crystals, the NASA Glenn Research Center at Lewis Field initiated an in depth investigation of the effect of heat treatment on the microstructure and subsequent 1027 C creep behavior of [001]-oriented NiAl-1Hf with a nominal chemistry of Ni-47.5Al-1Hf-0.5Si. This alloy was selected since four ingots, grown over a number of years and possessing slightly different compositions, were available for study. Specimens taken from the ingots were subjected to several heat treatment schedules, examined by transmission electron microscopy, and tested in both compression and tension. An example of the microstructure found in a [001]-oriented NiAl-1Hf specimen after a solution treatment at 1317 C for 50 hr followed by air cooling is illustrated in the image on the left, where the NiAl matrix contains a uniform distribution of nanometer-scale Gphase (Ni16Hf6Si7) precipitates. Other heat treating schedules produced microstructures with nanometer-sized G-phase cubes and plates or, in an extreme case, produced a microstructure with all the G-phase converted to Heusler (Ni2AlHf) particles. The results of 1027 C creep strength and strain rate testing are illustrated which summarizes data from tensile and compressive testing of samples cut from all four NiAl-1Hf ingots and subjected to a variety of heat treatment schedules. With one exception, all the strength values lie in a narrow band that spans six orders of magnitude in strain rate. The only factor that produced results outside of this band was the heat treatment schedule that dissolved all the G-phase and replaced it with Heusler precipitates. The results portrayed in this figure lead to the important practical conclusion that the elevated-temperature creep properties of NiAl-1Hf single crystals are reproducible and are not affected by small variations in alloy chemistry from ingot to ingot or by different initial distributions of G-phase in the heat-treated alloy. The only variable in this study that produced a significant and delerious effect on mechanical strength was a post-solution heat treatment that lead to the complete disappearance of the G-phase in favor of Heusler precipitates.

Whittenberger, J. Daniel↗