Differential cross sections and polarization observables from CLAS K ⁎ photoproduction and the search for new N ⁎ states
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A search for the K + → μ - νe + e + decay, forbidden within the Standard Model by either lepton number or lepton flavour conservation depending on the flavour of the emitted neutrino, has been performed using the dataset collected by the NA62 experiment at CERN in 2016--2018. An upper limit of 8.1×10 -11 is obtained for the decay branching fraction at 90% CL, improving by a factor of 250 over the previous search.
Chronic airway diseases are characterized by airway remodeling which is attributed partly to the proliferation and migration of airway smooth muscle cells (ASMCs). ATP-sensitive potassium (K{sub ATP}) channels have been identified in ASMCs. Mount evidence has suggested that K{sub ATP} channel openers can reduce airway hyperresponsiveness and alleviate airway remodeling. Opening K{sup +} channels triggers K{sup +} efflux, which leading to membrane hyperpolarization, preventing Ca{sup 2+}entry through closing voltage-operated Ca{sup 2+} channels. Intracellular Ca{sup 2+} is the most important regulator of muscle contraction, cell proliferation and migration. K{sup +} efflux decreases Ca{sup 2+} influx, which consequently influences ASMCs proliferation and migration. As a K{sub ATP} channel opener, iptakalim (Ipt) has been reported to restrain the proliferation of pulmonary arterial smooth muscle cells (PASMCs) involved in vascular remodeling, while little is known about its impact on ASMCs. The present study was designed to investigate the effects of Ipt on human ASMCs and the mechanisms underlying. Results obtained from cell counting kit-8 (CCK-8), flow cytometry and 5-ethynyl-2′-deoxyuridine (EdU) incorporation showed that Ipt significantly inhibited platelet-derived growth factor (PDGF)-BB-induced ASMCs proliferation. ASMCs migration induced by PDGF-BB was also suppressed by Ipt in transwell migration and scratch assay. Besides, the phosphorylation of Ca{sup 2+}/calmodulin-dependent kinase II (CaMKII), extracellular regulated protein kinases 1/2 (ERK1/2), protein kinase B (Akt), and cyclic adenosine monophosphate (cAMP) response element binding protein (CREB) were as well alleviated by Ipt administration. Furthermore, we found that the inhibition of Ipt on the PDGF-BB-induced proliferation and migration in human ASMCs was blocked by glibenclamide (Gli), a selective K{sub ATP} channel antagonist. These findings provide a strong evidence to support that Ipt antagonize the proliferating and migrating effects of PDGF-BB on human ASMCs through opening K{sub ATP} channels. Altogether, our results highlighted a novel profile of Ipt as a potent option against the airway remodeling in chronic airway diseases. - Highlights: Iptakalim is a novel ATP-sensitive potassium channel opener. Iptakalim showed anti-proliferation and anti-migration effects on PDGF-BB-induced human airway smooth muscle cells. Inhibitory effects of Iptakalim could be abolished by glibenclamide, a selective K{sub ATP} channel antagonist. Inhibitory effects of Iptakalim involved the signaling pathways of CaMKII, ERK1/2 and Akt, as well as their downstream, CREB.
Hyperhomocysteinemia induces the proliferation of vascular smooth muscle cells (VSMCs). Hydrogen sulfide (H{sub 2}S) inhibits the phenotype switch of VSMCs and calcium-sensing receptor (CaSR) regulated the production of endogenous H{sub 2}S. However, whether CaSR inhibits the proliferation of VSMCs by regulating the endogenous cystathionine-gamma-lyase (CSE, a major enzyme that produces H{sub 2}S) pathway in high homocysteine (HHcy) has not been previously investigated. The intracellular calcium concentration, the concentration of H{sub 2}S, the cell viability, the proliferation and the expression of proteins of cultured VSMCs from rat thoracic aortas were measured, respectively. The results showed that the [Ca{sup 2+}]{sub i} and the expression of p-CaMK and CSE increased upon treatment with CaSR agonist. In HHcy, the H{sub 2}S concentration decrease, the proliferation and migration rate increased, the expression of Cyclin D1, PCNA, Osteopontin and p-Erk1/2 increased while the α-SM actin, P21{sup Cip/WAK−1} and Calponin decreased. The CaSR agonist or exogenous H{sub 2}S significantly reversed the changes of VSMCs caused by HHcy. In conclusion, our results demonstrated that CaSR regulate the endogenous CSE/H{sub 2}S is related to the PLC-IP{sub 3} receptor and CaM signal pathways which inhibit the proliferation of VSMCs, and the latter is involved in the Erk1/2 dependent signal pathway in high homocysteine. - Highlights: • CaSR activation increased the production of endogenous H{sub 2}S in high homocysteine VSMCs. • CaSR modulated the CSE/H{sub 2}S are related to the PLC-IP{sub 3}R and Ca{sup 2+}-CaM signal pathways. • Inhibition of H{sub 2}S on the proliferation of VSMCs is involved in the Erk1/2 pathway. • Explore the potential roles of CaSR in regulating VSMCs proliferation in high homocysteine.
We present an analysis of the hyperon {Lambda}(1405) for p+p reactions at 3.5 GeV kinetic beam energy. The data were taken with the High Acceptance Di-Electron Spectrometer (HADES). A {Lambda}(1405) signal could be reconstructed in both charged decay channels ({Lambda}(1405){yields}{Sigma}{sup {+-}}{pi}{sup {+-}}).
We study the s-wave KN interactions in the isospin I = 0, 1 channels and associated exotic state {Theta}{sup +} from 2+1 flavor full lattice QCD simulation for relatively heavy quark mass corresponding to m{sub {pi}} = 871 MeV. The s-wave KN potentials are obtained from the Bethe-Salpeter amplitudes. Potentials in both channels reveal short range repulsions: Strength of the repulsion is stronger in the I = 1 potential. The I = 0 potential is found to have attractive well at mid range. The KN scattering phase shifts are calculated and compared with the experimental data.
Minimal SO(10) models which utilize a 126-plet of Higgs for breaking B - L symmetry are predictive schemes for neutrino masses and mixings. These models have been known to predict sin{sup 2}2{theta}{sub 13} Asymptotically-Equal-To 0.09, which is consistent with recent measurements. It is shown that the same class of models generates naturally baryon number violating dimension seven operators leading to novel nucleon decay modes such as n{yields}e{sup -}K{sup +}, e{sup -}{pi}{sup +} and p{yields}{nu}{pi}{sup +} which violate B - L by two units. We find that in two-step breaking schemes of non-supersymmetric SO(10), the partial lifetimes for these modes can be within reach of experiments. The interactions responsible for these decay modes also provide a new way to understand the origin of matter in the universe via the decays of GUT scale colored scalar bosons. Their (B - L)-violating nature guarantees that the GUT scale induced baryon asymmetry is not washed out by the electroweak sphaleron interactions. In minimal SO(10) models this asymmetry is closely tied to the masses of quarks, leptons and the neutrinos.
I consider the exclusive B{yields}K*{gamma}, B{yields}K*{sub 2}{gamma}, B{sub s}{yields}{phi}{gamma} and B{yields}K{eta}{sup ( Prime )}{gamma} radiative decays in the Standard Model and in a scenario with two universal extra dimensions compactified on a chiral square. Computed branching fractions depend on 1/R, the size of the extra dimensions, so that comparison with available data allows to put bounds on such a parameter. The most stringent bound comes from the mode B*{sup 0}{yields}K*{sup 0}{gamma} and reads: 1/R > 710 GeV.
We review the role of antikaons in recent versions of relativistic mean field models and focus on the interactions in which all parameters are obtained by fitting finite nuclear data and successfully applied to reproduce a variety of nuclear and neutron star (NS) properties. We show that the recently observed 1.97 solar mass NS can be explained in three ways: (i) A stiffer EoS with both antikaons (K{sup -}, K-bar {sup 0}), (ii) a relatively softer EoS with K{sup -} and (iii) a softer EoS with nucleon phase only.
In this work we evaluate the coupling constant for the vertex B{sub s}B*K by the QCD Sum Rules. The result was obtained using the heaviest particle off shell of this vertex, the B{sub s} meson, and the lightest particle off shell, the K meson.
A gyrating ion beam propagating through a magnetized plasma cylinder containing K{sup +} positive ions, electrons, and SF{sub 6}{sup -} negative ions drives electrostatic lower hybrid waves to instability via Cyclotron interaction. Numerical calculations of the unstable mode frequencies and growth rates of both the unstable positive ion and negative ion modes have been carried out for the existing negative ion plasma parameters. It is found that the unstable mode frequencies of both the modes increase, with the relative density of negative ions. In addition, the growth rates of both the unstable modes also increases with relative density of negative ions. Moreover, the growth rates of both the unstable modes scale as the one-third power of the beam density. The frequencies of both the unstable modes also increase with the magnetic fields. The real part of the unstable wave frequency increases as almost the square root of the beam energy.
The family (∂{sub k},∂{sub k}{sup *}){sub k≥0} of annihilation and creation operators acting on square integrable functionals of a Bernoulli process Z= (Z{sub k}){sub k⩾0} can be interpreted as quantum Bernoulli noises. In this note we consider the operator family (ℓ{sub k},ℓ{sub k}{sup *}){sub k≥0}, where ℓ{sub k}=∂{sub k}E{sub k} with E{sub k} being the conditional expectation (operator) given σ-field σ(Z{sub j}; 0 ⩽j⩽k). We show that ℓ{sub k} (resp. ℓ{sub k}{sup *}) is essentially a kind of localization of the annihilation operator ∂{sub k} (resp. creation operator ∂{sub k}{sup *}). We examine properties of the family (ℓ{sub k},ℓ{sub k}{sup *}){sub k≥0} and prove, among other things, that ℓ{sub k} and ℓ{sub k}{sup *} satisfy a local canonical anti-communication relation and (ℓ{sub k}{sup *}){sub k≥0} forms a mutually orthogonal operator sequence although each ℓ{sub k} is not a projection operator. We find that the operator series Σ{sub k=0}{sup ∞}ℓ{sub k}{sup *}Xℓ{sub k} converges in the strong operator topology for each bounded operator X acting on square integrable functionals of Z. In particular we get an explicit sum of the operator series Σ{sub k=0}{sup ∞}ℓ{sub k}{sup *}ℓ{sub k}. A useful norm estimate on Σ{sub k=0}{sup ∞}ℓ{sub k}{sup *}Xℓ{sub k} is also obtained. Finally we show applications of our main results to quantum dynamical semigroups and quantum probability.
Thermodynamic properties of aqueous solutions containing alkali and halide ions are determined by molecular simulation. The following ions are studied: Li{sup +}, Na{sup +}, K{sup +}, Rb{sup +}, Cs{sup +}, F{sup −}, Cl{sup −}, Br{sup −}, and I{sup −}. The employed ion force fields consist of one Lennard-Jones (LJ) site and one concentric point charge with a magnitude of ±1 e. The SPC/E model is used for water. The LJ size parameter of the ion models is taken from Deublein et al. [J. Chem. Phys. 136, 084501 (2012)], while the LJ energy parameter is determined in the present study based on experimental self-diffusion coefficient data of the alkali cations and the halide anions in aqueous solutions as well as the position of the first maximum of the radial distribution function of water around the ions. On the basis of these force field parameters, the electric conductivity, the hydration dynamics of water molecules around the ions, and the enthalpy of hydration is predicted. Considering a wide range of salinity, this study is conducted at temperatures of 293.15 and 298.15 K and a pressure of 1 bar.
We study forward neutrino-induced meson production off the nucleon in the resonance region. Our calculation is based on a dynamical coupled-channels (DCC) model that reasonably describes π(γ)N → πN, ηN, KΛ, KΣ data in the resonance region. We apply the PCAC hypothesis to the DCC model to relate the πN reaction amplitude to the forward neutrino reaction amplitude. In this way, we give a prediction for νN → πN, ππN, ηN, KΛ, KΣ reaction cross sections. The predicted νN → ππN, ηN, KΛ, KΣ cross sections are, for the first time, based on a model extensively tested by data. We compare our results with those from the Rein-Sehgal model that has been very often used in the existing Monte Carlo simulators for neutrino experiments. We find a significant difference between them.
The strange particle production induced by (anti)neutrino off nucleon has been studied for |ΔS| = 0 and |ΔS| = 1 channels. The reactions those we have considered are for the production of single kaon/antikaon, eta and associated particle production processes. We have developed a microscopical model based on the SU(3) chiral Lagrangian. The basic parameters of the model are f{sub π}, the pion decay constant, Cabibbo angle, the proton and neutron magnetic moments and the axial vector coupling constants for the baryons octet. For antikaon production we have also included Σ*(1385) resonance and for eta production S{sub 11}(1535) and S{sub 11}(1650) resonances are included.
We report on our recent study of the the neutrino-nucleon reaction in the nucleon resonance region. The dynamical reaction model of meson production reaction on the nucleon for the pion and photon induced reaction has been developed in order to investigate the spectrum of nucleon excited state. We have extended this model in order to describe the weak meson production reactions with the πN, ηN, KΛ, KΣ and ππN final states. We also studied the role of the final state interaction in the photon and the neutrino induced pion production reaction on the deuteron around the Δ(1232) resonance region.
We use a symmetry-preserving regularization method of ultraviolet divergences in a vector-vector contact interaction model for low-energy QCD. The contact interaction is a representation of nonperturbative kernels used Dyson-Schwinger and Bethe-Salpeter equations. The regularization method is based on a subtraction scheme that avoids standard steps in the evaluation of divergent integrals that invariably lead to symmetry violation. Aiming at the study of heavy-light mesons, we have implemented the method to the pseudoscalar π and K mesons. We have solved the Dyson-Schwinger equation for the u, d and s quark propagators, and obtained the bound-state Bethe-Salpeter amplitudes in a way that the Ward-Green-Takahashi identities reflecting global symmetries of the model are satisfied for arbitrary routing of the momenta running in loop integrals.
Despite its superb electronic properties, the semi-metallic nature of graphene with no band gap (E{sub g}) at the Dirac point has been a stumbling block for its industrial application. We report an improved means of producing a tunable band gap over other schemes by doping low energy (10 eV) potassium ions (K{sup +}) on single layer graphene formed on 6H-SiC(0001) surface, where the noble Dirac nature of the π-band remains almost unaltered. The changes in the π-band induced by K{sup +} ions reveal that the band gap increases gradually with increasing dose (θ) of the ions up to E{sub g} = 0.65 eV at θ = 1.10 monolayers, demonstrating the tunable character of the band gap. Our core level data for C 1s, Si 2p, and K 2p suggest that the K{sup +}-induced asymmetry in charge distribution among carbon atoms drives the opening of band gap, which is in sharp contrast with no band gap when neutral K atoms are adsorbed on graphene. This tunable K{sup +}-induced band gap in graphene illustrates its potential application in graphene-based nano-electronics.