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At least 739 records · Page 41

Aging impairs the osteocytic regulation of collagen integrity and bone quality

Poor bone quality is a major factor in skeletal fragility in elderly individuals. The molecular mechanisms that establish and maintain bone quality, independent of bone mass, are unknown but are thought to be primarily determined by osteocytes. We hypothesize that the age-related decline in bone quality results from the suppression of osteocyte perilacunar/canalicular remodeling (PLR), which maintains bone material properties. We examined bones from young and aged mice with osteocyte-intrinsic repression of TGFβ signaling (TβRII ocy–/– ) that suppresses PLR. The control aged bone displayed decreased TGFβ signaling and PLR, but aging did not worsen the existing PLR suppression in male TβRII ocy–/– bone. This relationship impacted the behavior of collagen material at the nanoscale and tissue scale in macromechanical tests. The effects of age on bone mass, density, and mineral material behavior were independent of osteocytic TGFβ. We determined that the decline in bone quality with age arises from the loss of osteocyte function and the loss of TGFβ-dependent maintenance of collagen integrity.

59 BASIC BIOLOGICAL SCIENCES↗

Shuttle Program Loads Integration: Going From Concept to Operations and Staying Successful

From the beginning of the Shuttle Program to its end, integrated loads and dynamics analyses and tests have been critical in shaping the vehicle design and operational decisions for NASA and its customers. Starting with scaled models and simple mathematical simulations of the structural dynamics, engineers defined the required structural stiffness and predicted the limit loads for each element of the system. Early structural tests provided reasonable confidence that the models and predictions were good. The first launch of the Space Shuttle brought surprises, though, when the ignition overpressure event caused a forward fuel tank support strut to buckle, among several unexpected effects. The launch pad and other ground equipment became an integral part of the system integration, especially where the acoustic and pressure environments of ignition and lift-off were concerned. Following the Challenger accident, operating limits were changed in response to new understandings of how the integrated system performed. Controlling loads while maximizing performance was a key tenet of the Performance Enhancement design process, which enabled construction of the International Space Station. During the return to flight after the Columbia accident, engineers grew to understand that loads during the roll maneuver were also important to the vehicle s structural margin and life. At this point the crawler transport from the Vehicle Assembly Building to the launch pad also became a part of the integrated loads analysis. Even in the last years of the Space Shuttle Program, new data still provided interesting insights into this complicated and fascinating spaceship. This paper will present some examples of the important findings by the team of specialists that supported the Integrated Loads and Dynamics Panel for the Space Shuttle Program.

Bernstein, Karen↗

A combined experimental and computational analysis of failure mechanisms in open-hole cross-ply laminates under flexural loading

In this work, integrated experimental tests and computational modeling are proposed to investigate the failure mechanisms of open-hole cross-ply carbon fiber reinforced polymer (CFRP) laminated composites. In particular, we propose two effective methods, which include width-tapered double cantilever beam (WTDCB) and fixed-ratio mixed-mode end load split (FRMMELS) tests, to obtain the experimental data more reliably. We then calibrate the traction-separation laws of cohesive zone model (CZM) used among laminas of the composites by leveraging these two methods. The experimental results of fracture energy, i.e. G Ic and G Tc , obtained from WTDCB and FRMMELS tests are generally insensitive to the crack length thus requiring no effort to accurately measure the crack tip. Moreover, FRMMELS sample contains a fixed mixed-mode ratio of G IIc /G Tc depending on the width taper ratio. Examining comparisons between experimental results of FRMMELS tests and failure surface of B–K failure criterion predicted from a curve fitting, good agreement between the predictions and experimental data has been found, indicating that FRMMELS tests are an effective method to determine mixed-mode fracture criterion. In addition, a coupled experimental-computational modeling of WTDCB, edge notched flexure, and FRMMELS tests are adopted to calibrate and validate the interfacial strengths. Finally, failure mechanisms of open-hole cross-ply CFRP laminates under flexural loading have been studied systematically using experimental and multi-scale computational analyses based on the developed CZM model. The initiation and propagation of delamination, the failure of laminated layers as well as load-displacement curves predicted from computational analyses are in good agreement with what we have observed experimentally.

36 MATERIALS SCIENCE↗

Deep Learning-enhanced Block-Diagram Modeling of Solar Power Systems

Data-driven models of power system inverter-based resources are desired to run simulations faster than with detailed electromagnetic transient models, to hide proprietary design details, to support control system design applications, and to aggregate the effects of distributed energy resources. This paper applies a customized Hammerstein Wiener framework to train block diagram models from thousands of electromagnetic transient simulations or experimental test records. The block diagram models integrate with larger grid simulations as voltagecontrolled current sources or current-controlled voltage sources for several simulators. Guidelines for block architecture and training are presented. Three-phase balanced, three-phase unbalanced, and single-phase examples all achieve an acceptable root mean square error of no more than 0.05 per-unit.

Mcdermott, Thomas E. [Private consulting company]↗

ORNL FACE Tree Height, with data on height of a subset of trees measured every year, 1997-2009. Free-Air CO2 Enrichment (FACE) Experiment Synthesis Activities.

Height of 20 sweetgum trees in three rows of each of the plots in the Oak Ridge National Laboratory (ORNL) free-air CO2 enrichment (FACE) experiment was measured each year of the experiment (1997-2009). The trees were exposed to ambient or elevated CO2. Tree height data contribute to the overall project objectives to determine the integrated response of a deciduous forest to elevated CO2. Average tree height per plot was used in allometric equations to calculate tree dry mass each year and to test whether there were effects of elevated CO2 on canopy development. Height was derived from trigonometric calculation from measurements of horizontal distance of observer from the bole and the angles from observer’s eye to top and base of tree, using a Haglof sonic hypsometer. The data are presented in a csv file, with plot number in the first column, tree number in the second column, and height recorded to 0.1 m in 1997 to 2009 in remaining columns. Plots 1 and 2 had elevated CO2, and plots 3-5 were in ambient CO2. Missing data occur after the tree died. The experiment and the height measurement are described in: Norby, R. J., D. E. Todd, J. Fults, and D. W. Johnson. 2001. Allometric determination of tree growth in a CO2-enriched sweetgum stand. New Phytologist 150: 477-487. The ORNL FACE experiment is described at: https://richnorby.org/home/face-home/.

54 ENVIRONMENTAL SCIENCES↗

A System Engineering Approach in the Analysis of Ionic Liquids Properties [Thesis]

Room temperature ionic liquids (RTIL) are ionic compounds, comprised of a cation and anion, in the liquid state at temperatures below 100 ⁰C. There are estimated 10 18 anion and cation combinations, which can create RTILs with unique properties. While the ionic character of RTILs made them attractive in a wide variety of electrochemical applications, their behaviors under electrochemical conditions are not well understood. In this research, we developed a RTIL testbed to investigate how RTILs differ from molecular solvents and electrolytes in electrochemical systems through the study of the effects of their morphology and chemical properties on the electron transfer processes. The test bed is composed of three modules: Electrochemistry, Material characterization, Computational. All modules have been completely developed, verified, and integrated and two of them, i.e., Electrochemistry and Material characterization have been validated in this dissertation. To evaluate the proposed system, experiments were performed on solutions of a redox active species in RTILs. It was found that it is possible to investigate the RTIL's morphology and chemical properties' impact on the electron transfer processes of the solute based on the outcomes and evaluations of tests performed by the RTIL testbed.

37 INORGANIC, ORGANIC, PHYSICAL, AND ANALYTICAL CH↗

Dynamics Informed Optimization for Resilient Energy Systems

Optimal mitigation planning for highly disruptive contingencies to a transmission-level power system requires optimization with dynamic power system constraints, due to the key role of dynamics in system stability to major perturbations. We formulate a generalized disjunctive program to determine optimal grid component hardening choices for protecting against major failures, with differential algebraic constraints representing system dynamics (specifically, differential equations representing generator and load behavior and algebraic equations representing instantaneous power balance over the transmission system). We optionally allow stochastic optimal pre-positioning across all considered failure scenarios, and optimal emergency control within each scenario. This novel formulation allows, for the first time, analyzing the resilience interdependencies of mitigation planning, preventive control, and emergency control. Using all three strategies in concert is particularly effective at maintaining robust power system operation under severe contingencies, as we demonstrate on the Western System Coordinating Council (WSCC) 9-bus test system using synthetic multi-device outage scenarios. Towards integrating our modeling framework with real threats and more realistic power systems, we explore applying hybrid dynamics to power systems. Our work is applied to basic RL circuits with the ultimate goal of using the methodology to model protective tripping schemes in the grid. Finally, we survey mitigation techniques for HEMP threats and describe a GIS application developed to create threat scenarios in a grid with geographic detail.

24 POWER TRANSMISSION AND DISTRIBUTION↗

SPARC-X: Quantum simulations at extreme scale - reactive dynamics from first principles

We have developed the massively parallel electronic structure code SPARC-X: a computational framework for performing Kohn-Sham Density Functional Theory (DFT) calculations that can scale linearly with the number of atoms in the system, while being able to leverage petascale and emerging exascale parallel computers to study chemical phenomena at unprecedented length and time scales. SPARC-X exploits a recent breakthrough in electronic structure methodologies: systematically improvable, strictly local, orthonormal, discontinuous real-space bases that efficiently and systematically capture the local chemistry of the system. With further adaptation using new machine-learning techniques and the use of the massively parallel Spectral Quadrature (SQ) electronic structure method, the algorithmic complexity and prefactor associated with DFT calculations involving semilocal as well as hybrid functionals are dramatically reduced. Using petascale computational resources, SPARC-X enables quantum mechanical simulations at length and time scales previously accessible only by empirical approaches, e.g., 1,000,000 atoms for a few picoseconds using semilocal functionals or 1,000 atoms for a few picoseconds using hybrid functionals. Using exascale resources, the sizes and times targeted are two orders of magnitude larger. Such a capability has applications in a wide variety of chemical sciences, including reactive interfaces where large length- and/or long time-scales are needed and traditional force fields fail. This is particularly important in dynamic catalysis, where bond breaking and formation must be understood in detail. We developed, tested, and employed the SPARC-X framework to understand the photocatalytic properties of TiO 2 nanoparticles, revealing finite size effects that cannot be captured with standard model systems or functionals. This integrated development and application strategy ensures that SPARC-X remains a robust, efficient, and scalable software package for quantum simulations on current petascale and emerging exascale computing resources.

97 MATHEMATICS AND COMPUTING↗

Methodology evaluation: Effects of independent verification and intergration on one class of application

The effects of an independent verification and integration (V and I) methodology on one class of application are described. Resource profiles are discussed. The development environment is reviewed. Seven measures are presented to test the hypothesis that V and I improve the development and product. The V and I methodology provided: (1) a decrease in requirements ambiguities and misinterpretation; (2) no decrease in design errors; (3) no decrease in the cost of correcting errors; (4) a decrease in the cost of system and acceptance testing; (5) an increase in early discovery of errors; (6) no improvement in the quality of software put into operation; and (7) a decrease in productivity and an increase in cost.

Page, J.↗

Optimal disturbance suppression with application to wind shear

A novel quadratic cost function composed of stochastic and deterministic contributions is used in the design of a digital flight control system for a small commercial jet with wind shear present. The optimal output feedback control design is configured to suppress the effect of the wind shear disturbance and maintain closed loop stability. A new algorithm is presented for finding the feedback gain. A proportional-integral control design with wind shear suppression is tested in a detailed nonlinear simulation of a commercial jet during the landing approach.

Broussard, J. R.↗

Acousto-ultrasonics

The theoretical development, methodology, and potential applications of acousto-ultrasonic nondestructive testing are set forth in an overview to assess the effectiveness of the technique. Stochastic wave propagation is utilized to isolate and describe defects in fiber-reinforced composites, particularly emphasizing the integrated effects of diffuse populations of subcritical flaws. The generation and nature of acousto-ultrasonic signals are described in detail, and stress-wave factor analysis of the signals is discussed. Applications of acousto-ultrasonics are listed including the prediction of failure sites, assessing fatique and impact damage, calculating ultimate tensile strength, and determining interlaminar bond strength. The method can identify subtle but important variations in fiber-reinforced composites, and development of the related instrumentation technology is emphasized.

Vary, Alex↗

NASA's hypersonic propulsion program: History and direction

Research into hypersonic propulsion; i.e., supersonic combustion, was seriously initiated at the Langley Research Center in the 1960's with the Hypersonic Research Engine (HRE) project. This project was designed to demonstrate supersonic combustion within the context of an engine module consisting of an inlet, combustor, and nozzle. In addition, the HRE utilized both subsonic and supersonic combustion (dual-mode) to demonstrate smooth operation over a Mach 4 to 7 speed range. The propulsion program thus concentrated on fundamental supersonic combustion studies and free jet propulsion tests for the three dimensional fixed geometry engine design to demonstrate inlet and combustor integration and installed performance potential. The developmental history of the program is presented. Additionally, the HRE program's effect on the current state of hypersonic propulsion is discussed.

Wander, Steve↗

Overview of the systems special investigation

The Systems Special Investigation Group (SIG), formed by the Long Duration Exposure Facility (LDEF) Project Office to perform post flight analysis of systems hardware, was chartered to investigate the effects of the extended LDEF mission on both satellite and experiment systems and to coordinate and integrate all systems analysis performed in post flight investigations. Almost all of the top level functional testing of the active experiments has been completed, but many components are still under investigation by either the Systems SIG or individual experimenters. Results reported to date have been collected and integrated by the Systems SIG and an overview of the current results and the status of the Systems Investigation are presented in this paper.

Mason, James B.↗

Development of a Crosslink Channel Simulator

Distributed Spacecraft missions are an integral part of current and future plans for NASA and other space agencies. Many of these multi-vehicle missions involve utilizing the array of spacecraft as a single, instrument requiring communication via crosslinks to achieve mission goals. NASA s Goddard Space Flight Center (GSFC) is developing the Formation Flying Test Bed (FFTB) to provide a hardware-in-the-loop simulation environment to support mission concept development and system trades with a primary focus on Guidance, Navigation, and Control (GN&C) challenges associated with spacecraft flying. The goal of the FFTB is to reduce mission risk by assisting in mission planning and analysis, provide a technology development platform that allows algorithms to be developed for mission functions such as precision formation navigation and control and time synchronization. The FFTB will provide a medium in which the various crosslink transponders being used in multi-vehicle missions can be integrated for development and test; an integral part of the FFTB is the Crosslink Channel Simulator (CCS). The CCS is placed into the communications channel between the crosslinks under test, and is used to simulate on-mission effects to the communications channel such as vehicle maneuvers, relative vehicle motion, or antenna misalignment. The CCS is based on the Starlight software programmable platform developed at General Dynamics Decision Systems and provides the CCS with the ability to be modified on the fly to adapt to new crosslink formats or mission parameters. This paper briefly describes the Formation Flying Test Bed and its potential uses. It then provides details on the current and future development of the Crosslink Channel Simulator and its capabilities.

Hunt, Chris↗

Tropical Convective Responses to Microphysical and Radiative Processes: A Sensitivity Study With a 2D Cloud Resolving Model

Prognostic cloud schemes are increasingly used in weather and climate models in order to better treat cloud-radiation processes. Simplifications are often made in such schemes for computational efficiency, like the scheme being used in the National Centers for Environment Prediction models that excludes some microphysical processes and precipitation-radiation interaction. In this study, sensitivity tests with a 2D cloud resolving model are carried out to examine effects of the excluded microphysical processes and precipitation-radiation interaction on tropical thermodynamics and cloud properties. The model is integrated for 10 days with the imposed vertical velocity derived from the Tropical Ocean Global Atmosphere Coupled Ocean-Atmosphere Response Experiment. The experiment excluding the depositional growth of snow from cloud ice shows anomalous growth of cloud ice and more than 20% increase of fractional cloud cover, indicating that the lack of the depositional snow growth causes unrealistically large mixing ratio of cloud ice. The experiment excluding the precipitation-radiation interaction displays a significant cooling and drying bias. The analysis of heat and moisture budgets shows that the simulation without the interaction produces more stable upper troposphere and more unstable mid and lower troposphere than does the simulation with the interaction. Thus, the suppressed growth of ice clouds in upper troposphere and stronger radiative cooling in mid and lower troposphere are responsible for the cooling bias, and less evaporation of rain associated with the large-scale subsidence induces the drying in mid and lower troposphere.

Li, Xiao-Fan↗

Role of Probabilistic Micromechanics Modeling in Establishing Design Allowables in Composites

One of the major challenges in designing with any new material, and particularly with advanced composite materials, is the fidelity of material design allowables. In the case of composite materials, the concern arises from the inherent nature of these materials, i.e., their heterogeneous make-up and the various factors that affect their properties in a specific design environment. Composites have various scales - micro, macro, laminate and structural, as well as numerous other fabrication related parameters. Many advanced composites in aerospace applications involve complex two- and three-dimensional fiber architectures and requires high-temperature processing. Since there are uncertainties associated with each of these, the observed behavior of composite materials shows scatter. Evaluating the effect of each of these variables on the observed scatter in composite properties solely by teSting is cost and time prohibitive. One alternative is to evaluate these effects by computational simulation. The authors have developed probabilistic composite micromechanics techniques by combining woven composite micromechanics and Fast Probability Integration (FPI) techniques to address these issues. In this paper these techniques will be described and demonstrated through selected examples. Results in the form of cumulative distribution functions (CDF) of the composite properties of a MI (melt-infiltrated) SiC/SiC (silicon carbide fiber in a silicon carbide matrix) Composite will be presented. A CDF is a relationship defined by the value of the property (the response variable) with respect to the cumulative probability of occurrence. Furthermore, input variables causing scatter are identified and ranked based upon their sensitivity magnitude. Sensitivity information is very valuable in quality control. How these results can be utilized to develop design allowables so that these materials may be used by structural analysts/designers will also be discussed.

Mital, Subodh K.↗

STS-114: Discovery Return to Flight: Langley Engineers Analysis Briefing

This video features a briefing on NASA Langley Research Center (LaRC) contributions to the Space Shuttle fleet's Return to Flight (RTF). The briefing is split into two sections, which LaRC Shuttle Project Manager Robert Barnes and Deputy Manager Harry Belvin deliver in the form of a viewgraph presentation. Barnes speaks about LaRC contributions to the STS-114 mission of Space Shuttle Discovery, and Belvin speaks about LaRC contributions to subsequent Shuttle missions. In both sections of the briefing, LaRC contributions are in the following areas: External Tank (ET), Orbiter, Systems Integration, and Corrosion/Aging. The managers discuss nondestructive and destructive tests performed on ET foam, wing leading edge reinforced carbon-carbon (RCC) composites, on-orbit tile repair, aerothermodynamic simulation of reentry effects, Mission Management Team (MMT) support, and landing gear tests. The managers briefly answer questions from reporters, and the video concludes with several short video segments about LaRC contributions to the RTF effort.

Source record↗

Using Thermoelectric Converters for Loop Heat Pipe Operating Temperature Control

This paper describes an experimental study to investigate the effectiveness of using thermoelectric converters (TECs) to control the loop heat pipe (LHP) operating temperature. Tests were conducted on an LHP having two evaporators and two condensers. Each evaporator has its own integral compensation chamber (CC). One side of the TEC is attached to the CC, and the other side is connected to the evaporator through a copper thermal strap. A bi-polar power supply is used to provide the power for the operation of each TEC. The bipolar supply will automatic change the direction of the current to the TEC depending on whether the CC requires heating or cooling in order to maintain its temperature at the desired set point. When cooling the CC, the heat pumped by the TEC plus the power needed to operate the TEC is dissipated to the evaporator, and is ultimately transmitted to the condenser. When heating the CC, the TEC can draw heat from the evaporator to supplement the required control heater power. Test results showed that the TEC could control the LHP operating temperature within h1K of the set point temperature. The control heater power required for TEC operation was also much less than that of using electrical heaters.

Ku, Jentung↗