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At least 739 records · Page 41

The Mariner Mars 1971 orbiter.

The Mariner Mars 1971 (MM '71) orbiter spacecraft, launched toward Mars in the spring of 1971, was designed to offer the first opportunity for sustained observations in the near vicinity of another planet of our solar system. The MM '71 spacecraft, like its predecessors, is fully attitude stabilized about three axes, using the sun and Canopus as references, an orientation which allows use of photovoltaic solar panels for primary power and permits two-way communication to the earth through a high-gain directional antenna. Midcourse and orbit insertion maneuvers use the sun-Canopus orientation as a reference direction for initiating commanded turns. Scientific instruments employed during Mars orbital operations are mounted on a two-degree-of-freedom platform controlled by commands from the central computer and sequencer. Science measurements to be obtained by the MM '71 spacecraft include television visual imaging, infrared radiometry, infrared spectroscopy, ultraviolet spectroscopy, S-band radio occultation, and celestial mechanics.

Scull, J. R.↗

The molecular complexes in Orion

Line emission from CO at 2.6 mm is observed over an area of 28 square degrees in the Orion region. Most of the emission comes from two giant molecular complexes, roughly associated with Ori B and Ori A. The latter provides the best example of a giant molecular complex at the end of a sequence of OB association subgroups of decreasing age. This complex is apparently rotating with an angular velocity 4.5 by 10 to the -15th power per sec, but in a direction opposed to the Galactic rotation. The apparently denser parts of the cloud are rotating at a somewhat greater angular velocity. The total mass of the molecular gas derived from the observations is 200,000 solar masses, implying that roughly half the matter in this region is in the form of molecular hydrogen.

Kutner, M. L.↗

Non-axisymmetric shapes of a rotating drop in an immiscible system

The nonaxisymmetric shapes of a rotating drop in an immiscible system were studied. Five basic families of shapes (axisymmetric, two-lobed, three-lobed, four-lobed, and toroidal) were observed. The sequence (axisymmetric to two-lobed to three-lobed to four-lobed to toroidal) seems to be linked to increasing spin-up velocity. For the axisymmetric case, direct comparisons of experiments with the theory of a free rotating drop were surprisingly good the equatorial area differs from theory by only 30%. Furthermore, the non-axisymmetric shapes are in good qualitative agreement with the theory, although the theory does not address the presence of an outer fluid.

Wang, T. G.↗

Coordinate generation with precise controls over mesh properties

Powerful local controls have been developed for mesh generation with the class of multisurface coordinate transformations. The controls come from local piecewise linear interpolants, and the resulting coordinates have continuous first derivatives. At the boundaries, the mesh controls provide the capability of joining distinct coordinate systems together with continuous derivatives. Away from boundaries, a local region can be given a particular mesh form to model internal objects or to simplify a problem. Applications of the controls are illustrated with a sequence of two-dimensional examples. For simplicity, each is generated about a NACA0012 airfoil which is of unit length and with leading edge pointed in a negative x-direction.

Eiseman, P. R.↗

Exact computation of the unwrapped phase of a finite-length time series

McGowan and Kuc (1982) showed that a direct relationship between a time series and its unwrapped phase exists. They proposed an algorithm for computing the unwrapped phase by counting the number of sign changes in a Sturm sequence generated from the real and imaginary parts of the discrete Fourier transform. Their algorithm is limited to relatively short sequences by numerical accuracy. An extension of their algorithm is proposed which, by using all-integer arithmetic, permits exact computation of the number of multiples of pi required to determine the unwrapped phase for rational-valued time sequences of arbitrary length. Since the computation is exact, the extended numerical algorithm should be of interest when accurate phase unwrapping is required.

Long, David G.↗

Hot-spot evolution and the global tectonics of Venus

The global tectonics of Venus may be dominated by plumes rising from the mantle and impinging on the lithosphere, giving rise to hot spots. Global sea-floor spreading does not take place, but direct convective coupling of mantle flow fields to the lithosphere leads to regional-scale deformation and may allow lithospheric transport on a limited scale. A hot-spot evolutionary sequence comprises (1) a broad domal uplift resulting from a rising mantle plume, (2) massive partial melting in the plume head and generation of a thickened crust or crustal plateau, (3) collapse of dynamic topography, and (4) creep spreading of the crustal plateau. Crust on Venus is produced by gradual vertical differentiation with little recycling rather than by the rapid horizontal creation and consumption characteristic of terrestrial sea-floor spreading.

Phillips, Roger J.↗

A full-coordinate model of the polymerase domain of HIV-1 reverse transcriptase and its interaction with a nucleic acid substrate

We present a full-coordinate model of residues 1-319 of the polymerase domain of HIV-I reverse transcriptase. This model was constructed from the x-ray crystallographic structure of Jacobo-Molina et al. (Jacobo-Molina et al., P.N.A.S. USA 90, 6320-6324 (1993)) which is currently available to the degree of C-coordinates. The backbone and side-chain atoms were constructed using the MAXSPROUT suite of programs (L. Holm and C. Sander, J. Mol. Biol. 218, 183-194 (1991)) and refined through molecular modeling. A seven base pair A-form dsDNA was positioned in the nucleic acid binding cleft to represent the template-primer complex. The orientation of the template-primer complex in the nucleic acid binding cleft was guided by the positions of phosphorus atoms in the crystal structure.

Non-NASA Center↗

Role of Deep Convection in Establishing the Isotopic Composition of Water Vapor in the Tropical Transition Layer

The transport of H2O and HDO within deep convection is investigated with 3-D large eddy simulations (LES) using bin microphysics. The lofting and sublimation of HDO-rich ice invalidate the Rayleigh fractionation model of isotopologue distribution within deep convection. Bootstrapping the correlation of the ratio of HDO to H2O (deltaD) to water vapor mixing ratio (q(sub v)) through a sequence of convective events produced non-Rayleigh correlations resembling observations. These results support two mechanisms for stratospheric entry. Deep convection can inject air with water vapor of stratospheric character directly into the tropical transition layer (TTL). Alternatively, moister air detraining from convection may be dehydrated via cirrus formation n the TTL to produce stratospheric water vapor. Significant production of subsaturated air in the TTL via convective dehydration is not observed in these simulations, nor is it necessary to resolve the stratospheric isotope paradox.

Smith, Jamison A.↗

Comparison of Statistical Estimation Techniques for Mars Entry, Descent, and Landing Reconstruction from MEDLI-like Data Sources

Flight data from an entry, descent, and landing (EDL) sequence can be used to reconstruct the vehicle's trajectory, aerodynamic coefficients and the atmospheric profile experienced by the vehicle. Past Mars missions have contained instruments that do not provide direct measurement of the freestream atmospheric conditions. Thus, the uncertainties in the atmospheric reconstruction and the aerodynamic database knowledge could not be separated. The upcoming Mars Science Laboratory (MSL) will take measurements of the pressure distribution on the aeroshell forebody during entry and will allow freestream atmospheric conditions to be partially observable. This data provides a mean to separate atmospheric and aerodynamic uncertainties and is part of the MSL EDL Instrumentation (MEDLI) project. Methods to estimate the flight performance statistically using on-board measurements are demonstrated here through the use of simulated Mars data. Different statistical estimators are used to demonstrate which estimator best quantifies the uncertainties in the flight parameters. The techniques demonstrated herein are planned for application to the MSL flight dataset after the spacecraft lands on Mars in August 2012.

Dutta, Soumyo↗

Probing Supraglacial Debris on Mars 2: Crater Morphology

Lobate debris aprons (LDA), lineated valley fill (LVF), and concentric crater fill (CCF) on Mars, interpreted to bedebris-covered glaciers, possess craters with a suite of distinct interior landforms (called "ring-mold craters")that have been attributed to the presence of glacial ice at depth or surface modification processes. We testedcurrent hypotheses for the formation of ring-mold craters by conducting a comprehensive analysis of the size andmorphology of 16,457 impact craters 125m in diameter formed within glacial deposits in DeuteronilusMensae. Two major groups, bowl-shaped craters and ring-mold craters, are found, with at least nine distinctcrater types. While there is statistical difference in median diameters between these crater types, this differenceis relatively small and is within the estimated uncertainty in diameter measurements and may be related to moreenhanced erosion of the rims of ring-mold craters. Clear degradation sequences are observed, supporting a rolefor post-impact modification in producing at least some of the diversity in crater landforms. The spatial densityof ring-mold craters is also directly correlated with the development of LDA, LVF, and CCF surface textures. Flowlineations cross-cut two ring-mold crater types but they maintain their circular planforms in some cases, suggestingthat the craters initially formed completely within mantling layers deposited after glacial flow hadceased. We also find analogous craters in non-glacial units; glacial ice is therefore not required to form theobserved morphologic diversity. Our observations are most consistent with formation of crater landforms byemplacement and modification of at least two depositional episodes of icy dust (i.e., "mantle"). This mantle wasinitially tens of meters in thickness to support crater formation, and has experienced much downwasting anderosion since emplacement. Derived crater retention ages of 460 Ma for LDA, LVF, and CCF features in the regiontherefore reflect deposition of mantle units and only give a very minimum age for the formation of LDA, LVF, andCCF

Geological↗

GL4U: Using Space Biology Omics Data to Provide Bioinformatics Training for Students and Educators

NASA’s GeneLab project provides researchers open access to space-relevant multi-omics data via the Open Science Data Repository (OSDR) that can be mined to understand the effects of spaceflight on biological systems. To maximize the number of scientists who understand and utilize GeneLab data and data processing pipelines, GeneLab created GeneLab for Colleges and Universities (GL4U). GL4U provides space biology-relevant training in bioinformatics to the next generation of scientists through direct (training students) and indirect (training educators) approaches. The GL4U pilot programs were conducted in June 2021 (direct training) and 2022 (indirect training). During the pilots, students and educators at Historically Black Colleges and Universities (HBCUs) and Minority Serving Institutions (MSIs) participated in a week-long (direct training) or two-week-long (indirect training) bootcamp consisting of space biology-specific lectures and hands-on instruction using Jupyter Notebooks to analyze space biology RNA sequencing data from OSDR. During the educator pilot, participants received materials, training, and the necessary compute resources to enable them to run the bootcamp at their home institutions, thereby extending the reach of this initiative. In July 2023, GeneLab is partnering with JPL to expand GL4U to include amplicon sequencing (Amp-Seq) analysis training. During the GL4U Amp-Seq bootcamp, student and educator participants will receive training on how to analyze and interpret Amp-Seq data using the NASA GeneLab data processing pipeline. All bootcamp material, including instructions for requesting compute resources, will be made publicly available on GitHub for educators to teach the GL4U content in subsequent semesters. GL4U provides undergraduate students from underrepresented groups the opportunity to learn about NASA and Space Biology, and to enhance their career prospects by gaining hands-on experience analyzing omics data, a skillset that is highly applicable and marketable in the life sciences. We present results from pre- and post-training surveys completed by all participants of the Amp-Seq bootcamp.

Amanda M Saravia-Butler↗

Direct tests of cytochrome c and c 1 functions in the electron transport chain of malaria parasites

The mitochondrial electron transport chain (ETC) of Plasmodium malaria parasites is a major antimalarial drug target, but critical cytochrome (cyt) functions remain unstudied and enigmatic. Parasites express two distinct cyt c homologs (c and c-2) with unusually sparse sequence identity and uncertain fitness contributions. P. falciparum cyt c-2 is the most divergent eukaryotic cyt c homolog currently known and has sequence features predicted to be incompatible with canonical ETC function. We tagged both cyt c homologs and the related cyt c1 for inducible knockdown. Translational repression of cyt c and cyt c1 was lethal to parasites, which died from ETC dysfunction and impaired ubiquinone recycling. In contrast, cyt c-2 knockdown or knockout had little impact on blood-stage growth, indicating that parasites rely fully on the more conserved cyt c for ETC function. Biochemical and structural studies revealed that both cyt c and c-2 are hemylated by holocytochrome c synthase, but UV-vis absorbance and EPR spectra strongly suggest that cyt c-2 has an unusually open active site in which heme is stably coordinated by only a single axial amino acid ligand and can bind exogenous small molecules. These studies provide a direct dissection of cytochrome functions in the ETC of malaria parasites and identify a highly divergent Plasmodium cytochrome c with molecular adaptations that defy a conserved role in eukaryotic evolution.

60 APPLIED LIFE SCIENCES↗

Tip-based proximity ferroelectric switching and piezoelectric response in wurtzite multilayers

Proximity ferroelectricity is a paradigm for inducing ferroelectricity when a nonferroelectric polar material (such as Al⁢ N), which is unswitchable with an external field below the dielectric breakdown field, becomes a practically switchable ferroelectric in direct contact with a thin switchable ferroelectric layer (such as Al 1−𝑥 ⁢Sc 𝑥 ⁢N). Here, we develop a Landau-Ginzburg-Devonshire approach to study the proximity effect of local piezoelectric response and polarization reversal in wurtzite ferroelectric multilayers under a sharp electrically biased tip. Using finite-element modeling, we analyze the probe-induced nucleation of nanodomains, the features of local polarization hysteresis loops and coercive fields in the Al 1−𝑥 ⁢Sc 𝑥 ⁢N/Al⁢ N bilayers and three-layers. Similar to the wurtzite multilayers sandwiched between two parallel electrodes, the regimes of “proximity switching” (when all layers collectively switch) and the regime of “proximity suppression” (when they collectively do not switch) are the only two possible regimes in the probe-electrode geometry. However, the parameters and asymmetry of the local piezoresponse and polarization hysteresis loops depend significantly on the sequence of the layers with respect to the probe. The physical mechanism of proximity ferroelectricity in the local probe geometry is a depolarizing electric field determined by the polarization of the layers and their relative thickness. The field, whose direction is opposite to the polarization vector in the layer(s) with the larger spontaneous polarization (such as Al⁢ N), renormalizes the double-well ferroelectric potential to lower the steepness of the switching barrier in the “otherwise unswitchable” polar layers. Tip-based control of domains in otherwise nonferroelectric layers using proximity ferroelectricity can provide nanoscale control of domain reversal in memory, actuation, sensing, and optical applications. The ability of the tip-induced proximity switching to differentially switch multilayers, based on the order of the layers, provides a powerful tool for selective domain engineering.

36 MATERIALS SCIENCE↗

Kinematic principles of primate rotational vestibulo-ocular reflex. I. Spatial organization of fast phase velocity axes

The spatial organization of fast phase velocity vectors of the vestibulo-ocular reflex (VOR) was studied in rhesus monkeys during yaw rotations about an earth-horizontal axis that changed continuously the orientation of the head relative to gravity ("barbecue spit" rotation). In addition to a velocity component parallel to the rotation axis, fast phases also exhibited a velocity component that invariably was oriented along the momentary direction of gravity. As the head rotated through supine and prone positions, torsional components of fast phase velocity axes became prominent. Similarly, as the head rotated through left and right ear-down positions, fast phase velocity axes exhibited prominent vertical components. The larger the speed of head rotation the greater the magnitude of this fast phase component, which was collinear with gravity. The main sequence properties of VOR fast phases were independent of head position. However, peak amplitude as well as peak velocity of fast phases were both modulated as a function of head orientation, exhibiting a minimum in prone position. The results suggest that the fast phases of vestibulo-ocular reflexes not only redirect gaze and reposition the eye in the direction of head motion but also reorient the eye with respect to earth-vertical when the head moves relative to gravity. As further elaborated in the companion paper, the underlying mechanism could be described as a dynamic, gravity-dependent modulation of the coordinates of ocular rotations relative to the head.

Non-NASA Center↗

Shape-Shifting Peptide Nanomaterials: Surface Asymmetry Enables pH-Dependent Formation and Interconversion of Collagen Tubes and Sheets

The fabrication of dynamic, transformable biomaterials that respond to environmental cues represents a significant step forward in the development of synthetic materials that rival their highly functional, natural counterparts. In this work, we describe the design and synthesis of crystalline supramolecular architectures from charge-complementary heteromeric pairs of collagen-mimetic peptides (CMPs). Under appropriate conditions, CMP pairs spontaneously assemble into either 1D ultraporous (pore diameter >100 nm) tubes or 2D bilayer nanosheets due to the structural asymmetry that arises from heteromeric self-association. Crystalline collagen tubes represent a heretofore unobserved morphology of this common biomaterial. In-depth structural characterization from a suite of biophysical methods, including TEM, AFM, high-resolution cryo-EM, and SAXS/WAXS measurements, reveals that the sheet and tube assemblies possess a similar underlying lattice structure. The experimental evidence suggests that the tubular structures are a consequence of the self-scrolling of incipient 2D layers of collagen triple helices and that the scrolling direction determines the formation of two distinct structural isoforms. Furthermore, we show that nanosheets and tubes can spontaneously interconvert through manipulation of the assembly pH and systematic adjustment of the CMP sequence. Altogether, we establish initial guidelines for the construction of dynamically responsive 1D and 2D assemblies that undergo a structurally programmed morphological transition.

37 INORGANIC, ORGANIC, PHYSICAL, AND ANALYTICAL CH↗

Dynamics and control of escape and rescue from a tumbling spacecraft

Papers on the problem of controlling a tumbling spacecraft before crew rescue is affected are presented. Fluid jets are considered; It is concluded that a gas jet results in long tumble times and low utilization efficiencies and a liquid jet appears more attractive because it can be directed. A conceptual design of an unmanned antitumbling module for automatic dock and detumble is formulated, and analyses of its dynamics and control, synthesis of position and attitude control systems, and sequence of operations are given. The minimum time detumble operation is analyzed with respect to (1) to a constraint on the magnitude of the control moment vector and (2) to constraints on the magnitude of each of the three components of the control moment vector. Internal passive and active mechanisms of energy dissipation are also considered. Structural flexibility modelling techniques and detumbling effects of structural flexibility on free-tumbling motion, are reviewed. Mass expulsion, momentum exchange, and moveable mass techniques are described, and methods of analyzing these devices are surveyed.

Kaplan, M. H.↗

Elucidating the factors controlling the methanol synthesis from CO 2 on ZnPd-ZnO/TiO 2 catalysts prepared by direct/inverse impregnation

The direct hydrogenation of CO 2 to methanol over supported ZnPd intermetallic catalysts remains a challenge due to the complex nature of the active sites, which are highly dependent on both the dispersion of ZnPd intermetallics and their proximity to ZnO. This study investigates the effect of the Pd and Zn incorporation order on methanol synthesis over TiO 2 -supported ZnPd catalysts. Catalysts were prepared via direct (Pd/Zn), inverse (Zn/Pd), and co-impregnation (Pd+Zn) methods using anatase TiO 2 as the support. Comprehensive characterization by XRD, HRTEM, CO-DRIFTS and XPS revealed that the formation of small and crystalline intermetallic β-ZnPd particles and their interaction with ZnO/ZnO x depends on the sequence of Pd and Zn incorporation. It was found that, under the reaction conditions, the ZnO x species plays a critical role in facilitating the formation of the intermetallic ZnPd through the interactions between Pd and ZnO x . In addition, ZnO x species have also been shown to modulate key catalytic properties, such as CO 2 activation and methanol selectivity. Specifically, the ZnPd/Pd surface ratio, determined by Pd dispersion and proximity to ZnO/ZnO x , was shown to determine the methanol production from CO 2 directly or via a CO intermediate. The Pd/Zn catalyst showed superior selectivity due to the in-situ formation of intermetallic species facilitated by Pd-ZnO x interactions.

37 INORGANIC, ORGANIC, PHYSICAL, AND ANALYTICAL CH↗

Ram accelerator direct launch system for space cargo

The ram accelerator, a chemically-propelled mass driver, is presented as a new approach for directly launching acceleration-insensitive pay-loads into LEO. The cargo vehicle resembles the centerbody of a conventional ramjet and travels through a launch tube filled with a premixed gaseous fuel and oxidizer mixture. The tube acts as the outer cowling of the ramjet and the combustion process travels with the vehicle. Two modes of ram accelerator drive are described, which when used in sequence, are capable of accelerating the cargo vehicle to 10 km/sec. The requirements for placing a 2000 kg vehicle with 50 percent payload fraction into a 400 km orbit, with a minimum of on-board rocket propellant for circularization maneuvers, are examined. It is shown that aerodynamic heating during atmospheric transit results in very little ablation of the nose. Both direct and indirect orbital insertion scenarios are investigated, and a three-step maneuver consisting of two burns and aerobraking is found to minimize the on-board propellant mass. A scenario involving a parking orbit below the desired final orbit is suggested as a means to increase the flexibility of the mass launch concept.

Bruckner, A. P.↗