Discovery of PF-06873600, a CDK2/4/6 Inhibitor for the Treatment of Cancer
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Nanocomposite liposomes are relatively stable in weak basic solutions but effectively release porphyrins at acidic pH, as indicated by the difference in fluorescence.
The CLP5 self-assembles into spherical aggregates and encapsulates doxorubicin to form the CLP5@DOX nanomedicine, which exerts a combined antitumor effect by targeting caspase-3 and penetrating the cell membrane.
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