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At least 739 records · Page 41

SU-D-17A-04: The Impact of Audiovisual Biofeedback On Image Quality During 4D Functional and Anatomic Imaging: Results of a Prospective Clinical Trial

Purpose: The ability of audiovisual (AV) biofeedback to improve breathing regularity has not previously been investigated for functional imaging studies. The purpose of this study was to investigate the impact of AV biofeedback on 4D-PET and 4D-CT image quality in a prospective clinical trial. We hypothesized that motion blurring in 4D-PET images and the number of artifacts in 4D-CT images are reduced using AV biofeedback. Methods: AV biofeedback is a real-time, interactive and personalized system designed to help a patient self-regulate his/her breathing using a patient-specific representative waveform and musical guides. In an IRB-approved prospective clinical trial, 4D-PET and 4D-CT images of 10 lung cancer patients were acquired with AV biofeedback (AV) and free breathing (FB). The 4D-PET images in 6 respiratory bins were analyzed for motion blurring by: (1) decrease of GTVPET and (2) increase of SUVmax in 4-DPET compared to 3D-PET. The 4D-CT images were analyzed for artifacts by: (1) comparing normalized cross correlation-based scores (NCCS); and (2) quantifying a visual assessment score (VAS). A two-tailed paired t-test was used to test the hypotheses. Results: The impact of AV biofeedback on 4D-PET and 4D-CT images varied widely between patients, suggesting inconsistent patient comprehension and capability. Overall, the 4D-PET decrease of GTVPET was 2.0±3.0cm3 with AV and 2.3±3.9cm{sup 3} for FB (p=0.61). The 4D-PET increase of SUVmax was 1.6±1.0 with AV and 1.1±0.8 with FB (p=0.002). The 4D-CT NCCS were 0.65±0.27 with AV and 0.60±0.32 for FB (p=0.32). The 4D-CT VAS was 0.0±2.7 (p=ns). Conclusion: A 10-patient study demonstrated a statistically significant reduction of motion blurring of AV over FB for 1/2 functional 4D-PET imaging metrics. No difference between AV and FB was found for 2 anatomic 4D-CT imaging metrics. Future studies will focus on optimizing the human-computer interface and including patient training sessions for improved comprehension and capability. Supported by NIH/NCI R01 CA 093626, Stanford BioX Interdisciplinary Initiatives Program, NHMRC Australia Fellowship, and Kwanjeong Educational Foundation. GE Healthcare provided the Respiratory Gating Toolbox for 4D-PET image reconstruction. Stanford University owns US patent #E7955270 which is unlicensed to any commercial entity.

60 APPLIED LIFE SCIENCES↗

Design and implementation of a data analysis pipeline for paper spray ionization mass spectrometry of UO 2 Cl 2

Ambient mass spectrometry is an emerging characterization method for nuclear materials analysis. SRNL has recently acquired a new JEOL AccuTOF™-DART® LP 4G with a Filter Spray™ front end sample injection system, to develop new methods for ambient mass spectrometry of uranium analytes. Preliminary measurements of uranium-containing samples have demonstrated a need to rapidly evaluate large datasets generated with tailored data analysis scripts. To address this gap a data analysis pipeline written in R within the R Studio environment has been developed. The pipeline comprises a series of processing steps where the data are ingested, analyte peaks of interest are extracted, subsequent ratio and normalization calculations are performed, and results are presented in a series of graphical plots. In detail, the data files containing up to several hundred chronological spectra of a single sample in netCDF format were first extracted into RStudio. Then, initial 3D plots of the data were created in respect to the time, intensity, and mass to charge domains. These graphics serve as an initial easily visualized survey of instrument data. Next, a .csv format file containing the names, masses, and abundances of isotopes of interest were ingested into RStudio and were used to automatically collect intensity values at the mass value. Uranium isotope ratios were plotted against gadolinium isotope ratios (gadolinium was used as an internal standard) and assessed for ion beam stability and intensity. The spectra were filtered by applying a threshold intensity for the 158GdO+ mass channel. A Monte Carlo experiment was performed by creating a theoretical distribution of the data in order to determine the ratio of the uranium isotopes. The results show that the developed data analysis pipeline successfully filters high quality data from overall poor quality runs. Our results also support the idea that paper spray ionization mass spectrometry can be used for both detection and quantification of trace amounts of uranium compounds.

11 NUCLEAR FUEL CYCLE AND FUEL MATERIALS↗

Realtime Three-Dimensional Simulation

Real-time three-dimensional simulations are dependent of three areas: databases and models (3D geometric polygon structure, multiple levels of detail, sound sample waveforms, optimized for interactive, real time use); software applications (software program that controls input devices, visual channels, scene objects, interaction, collision detection, special effects, time of day, weather, I/O, and communication); and hardware (computer, sound processor, monitors control sticks, position trackers, head-mounted displays, amplifiers, speakers, and communications.

Ramsdell, Craig↗

Biological Visualization, Imaging and Simulation(Bio-VIS) at NASA Ames Research Center: Developing New Software and Technology for Astronaut Training and Biology Research in Space

The Bio- Visualization, Imaging and Simulation (BioVIS) Technology Center at NASA's Ames Research Center is dedicated to developing and applying advanced visualization, computation and simulation technologies to support NASA Space Life Sciences research and the objectives of the Fundamental Biology Program. Research ranges from high resolution 3D cell imaging and structure analysis, virtual environment simulation of fine sensory-motor tasks, computational neuroscience and biophysics to biomedical/clinical applications. Computer simulation research focuses on the development of advanced computational tools for astronaut training and education. Virtual Reality (VR) and Virtual Environment (VE) simulation systems have become important training tools in many fields from flight simulation to, more recently, surgical simulation. The type and quality of training provided by these computer-based tools ranges widely, but the value of real-time VE computer simulation as a method of preparing individuals for real-world tasks is well established. Astronauts routinely use VE systems for various training tasks, including Space Shuttle landings, robot arm manipulations and extravehicular activities (space walks). Currently, there are no VE systems to train astronauts for basic and applied research experiments which are an important part of many missions. The Virtual Glovebox (VGX) is a prototype VE system for real-time physically-based simulation of the Life Sciences Glovebox where astronauts will perform many complex tasks supporting research experiments aboard the International Space Station. The VGX consists of a physical display system utilizing duel LCD projectors and circular polarization to produce a desktop-sized 3D virtual workspace. Physically-based modeling tools (Arachi Inc.) provide real-time collision detection, rigid body dynamics, physical properties and force-based controls for objects. The human-computer interface consists of two magnetic tracking devices (Ascention Inc.) attached to instrumented gloves (Immersion Inc.) which co-locate the user's hands with hand/forearm representations in the virtual workspace. Force-feedback is possible in a work volume defined by a Phantom Desktop device (SensAble inc.). Graphics are written in OpenGL. The system runs on a 2.2 GHz Pentium 4 PC. The prototype VGX provides astronauts and support personnel with a real-time physically-based VE system to simulate basic research tasks both on Earth and in the microgravity of Space. The immersive virtual environment of the VGX also makes it a useful tool for virtual engineering applications including CAD development, procedure design and simulation of human-system systems in a desktop-sized work volume.

Smith, Jeffrey↗

Teleoperation and Visualization Interfaces for Remote Intervention in Space

Approaches to robotic manufacturing, assembly, and servicing of in-space assets range from autonomous operation to direct teleoperation, with many forms of semi-autonomous teleoperation in between. Because most approaches require one or more human operators at some level, it is important to explore the control and visualization interfaces available to those operators, taking into account the challenges due to significant telemetry time delay. We consider one motivating application of remote teleoperation, which is ground-based control of a robot on-orbit for satellite servicing. This paper presents a model-based architecture that: 1) improves visualization and situation awareness, 2) enables more effective human/robot interaction and control, and 3) detects task failures based on anomalous sensor feedback. We illustrate elements of the architecture by drawing on 10 years of our research in this area. The paper further reports the results of several multi-user experiments to evaluate the model-based architecture, on ground-based test platforms, for satellite servicing tasks subject to round-trip communication latencies of several seconds. The most significant performance gains were obtained by enhancing the operators’ situation awareness via improved visualization and by enabling them to precisely specify intended motion. In contrast, changes to the control interface, including model-mediated control or an immersive 3D environment, often reduced the reported task load but did not significantly improve task performance. Considering the challenges of fully autonomous intervention, we expect that some form of teleoperation will continue to be necessary for robotic in-situ servicing, assembly, and manufacturing tasks for the foreseeable future. We propose that effective teleoperation can be enabled by modeling the remote environment, providing operators with a fused view of the real environment and virtual model, and incorporating interfaces and control strategies that enable interactive planning, precise operation, and prompt detection of errors.

space robotics↗

Moon Tycoon Version 2: A 3D Lunar Surface Emulator for Desktops and Virtual Reality

Moon Tycoon Version 2 (V2) enables and encourages in-situ resource utilization (ISRU) technology developers, principal investigators (PI), and managers across the agency to design and visualize various Lunar operations and missions with a high degree of photorealism. Users are completely immersed in the emulated Moon environment, enabling them to gain new knowledge as they explore the Lunar surface. Moon Tycoon V2 will soon be released to the NASA Software Catalog for public distribution, which will allow external partners, academia, and other interested parties from the public domain to take part.

Kurt Leucht↗

Clear as mud redefined: Tunable transparent mineral scaffolds for visualizing microbial processes below ground

Microbes inhabiting complex porous microenvironments in sediments and aquifers catalyze reactions that are critical to global biogeochemical cycles and ecosystem health. However, the opacity and complexity of porous sediment and rock matrices have considerably hindered the study of microbial processes occurring within these habitats. Here, we generated microbially compatible, optically transparent mineral scaffolds to visualize and investigate microbial colonization and activities occurring in these environments, in laboratory settings and in situ. Using inexpensive synthetic cryolite mineral, we produced optically transparent scaffolds mimicking the complex 3D structure of sediments and rocks by adapting a suspension-based, freeze-casting technique commonly used in materials science. Fine-tuning of parameters, such as freezing rate and choice of solvent, provided full control of pore size and architecture. The combined effects of scaffold porosity and structure on the movement of microbe-sized particles, tested using velocity tracking of fluorescent beads, showed diverse yet reproducible behaviors. The scaffolds we produced are compatible with epifluorescence microscopy, allowing the fluorescence-based identification of colonizing microbes by DNA-based staining and fluorescence in situ hybridization (FISH) to depths of 100 µm. Additionally, Raman spectroscopy analysis indicates minimal background signal in regions used for measuring deuterium and 13 C enrichment in microorganisms, highlighting the potential to directly couple D 2 O or 13 C stable isotope probing and Raman-FISH for quantifying microbial activity at the single-cell level. To demonstrate the relevance of cryolite scaffolds for environmental field studies, we visualized their colonization by diverse microorganisms within rhizosphere sediments of a coastal seagrass plant using epifluorescence microscopy. The tool presented here enables highly resolved, spatially explicit, and multimodal investigations into the distribution, activities, and interactions of underground microbes typically obscured within opaque geological materials until now.

36 MATERIALS SCIENCE↗

CFD Model Development and validation for High Temperature Gas Cooled Reactor Cavity Cooling System (RCCS) Applications

The Reactor Cavity Cooling Systems (RCCS) is a passive safety system that will be incorporated in the VTHR design. The system was designed to remove the heat from the reactor cavity and maintain the temperature of structures and concrete walls under desired limits during normal operation (steady-state) and accident scenarios. A small scale (1:23) water-cooled experimental facility was scaled, designed, and constructed in order to study the complex thermohydraulic phenomena taking place in the RCCS during steady-state and transient conditions. The facility represents a portion of the reactor vessel with nine stainless steel coolant risers and utilizes water as coolant. The facility was equipped with instrumentation to measure temperatures and flow rates and a general verification was completed during the shakedown. A model of the experimental facility was prepared using RELAP5-3D and simulations were performed to validate the scaling procedure. The experimental data produced during the steady-state run were compared with the simulation results obtained using RELAP5-3D. The overall behavior of the facility met the expectations. The facility capabilities were confirmed to be very promising in performing additional experimental tests, including flow visualization, and produce data for code validation.

21 SPECIFIC NUCLEAR REACTORS AND ASSOCIATED PLANTS↗

VERAView User's Manual

VERAView has been developed as an interactive graphical interface for the visualization and engineering analyses of output data from VERA. The Python-based software is easy to install, intuitive to use, and provides instantaneous 2D and 3D images, 1D plots, and alpha-numeric data from VERA multi-physics simulations. This document provides a brief overview of the software and some description of the major features of the application, including examples of each of the encapsulated “widgets” that have been implemented thus far. VERAView is still under major development and large changes in the software and this document are still anticipated.

97 MATHEMATICS AND COMPUTING↗

Flow visualization

Flow visualization techniques are reviewed, with particular attention given to those applicable to liquid helium flows. Three techniques capable of obtaining qualitative and quantitative measurements of complex 3D flow fields are discussed including focusing schlieren, particle image volocimetry, and holocinematography (HCV). It is concluded that the HCV appears to be uniquely capable of obtaining full time-varying, 3D velocity field data, but is limited to the low speeds typical of liquid helium facilities.

Weinstein, Leonard M.↗

TU-H-CAMPUS-TeP1-04: Novel 3D Printed Plastic Cutouts Filled with Aluminum Oxide for Same Day Electron Radiotherapy

Purpose: Clinics that outsource electron cutout manufacturing may be unable to simulate and treat patients on the same day. To enable same day treatment, we investigate the use of 3D printed hollow cutouts filled with 30 grit Al{sub 2}O{sub 3} powder. We verified the dosimetric equivalence of such a cutout relative to an outsourced Copper cutout. Methods: Printing was performed using a Ultibots Kossel 250 V-Slot 3D printer and polylactic acid filament. Printing files were derived from an in-house 3D model designed to mate with a Varian 6 cm electron cone. Relative to conventional cutouts (Copper or Cerrobend), the height of the hollow plastic cutout was extended by 1.0 cm to increase attenuation. Measurements were performed for 6 MeV in solid water at dmax (1.4 cm) with Gafchromic™ EBT3 film; the cutout was kidney-shaped with a long and short axis of approximately 5 and 2 cm, respectively. The Copper cutout was based on an outline of the 3D printed cutout.A calibration film was exposed immediately after the electron irradiations. All films, including an un-irradiated one, were from the same batch. Films were scanned on an Epson 10000XL flatbed scanner. Film analysis was performed in DoseLab (MOBIUS Medical Systems, Houston, Tx). Results: Visual comparison of the physical cutouts revealed that the Copper cutout had a slightly smaller opening than the printed cutout. Line profiles through the registered films indicated agreement within 5% in the open section. 99.9% of pixels passed gamma analysis with 2% local percent difference, 2 mm DTA, and a 25% threshold. Conclusion: Same day simulation and treatment with electrons is feasible with 3D printing of a hollow cutout filled with Al{sub 2}O{sub 3}. Future work will include evaluations of additional cutout shapes at different depths for higher energies. Other printing materials, such as bismuth, are being tested.

60 APPLIED LIFE SCIENCES↗

High Performance, Web-Based, Real-Time Telemetry Visualization for Deep Space Mission Support and Operations

The Jet Propulsion Laboratory’s Mission ControlSystems Section and Mobility and Robotic Systems Section havepartnered to developed a high-performance telemetry visualizationsystem, based on our mature, web-based, 3D visualizationsoftware technology, that provides mission trajectory designers,operations personnel and reconstruction analysts with a highlyaccurate, re-usable, multi-mission solution to interactively visualizeresults from Entry, Descent and Landing (EDL) simulations,real-time mission test beds, live telemetry streams during criticalmission events, such as landing, as well as post-event reconstructionanalysis. This work builds on previous mission visualizationsystems that we have deployed for a variety of flight missions andJPL organizations including NASA’s Mars Science Laboratory(MSL), NASA’S Low Density Supersonic Decelerator (LDSD),NASA’s Soil Moisture Active Passive (SMAP), JPL’s MoonRiseLunar sample return proposal. JPL’s mission design teams, JPL’sOffice of Naval Research tasks, and JPL’s Education and PublicOutreach Office.

Wenzel, Sean↗

3D-Sonification for Obstacle Avoidance in Brownout Conditions

Helicopter brownout is a phenomenon that occurs when making landing approaches in dusty environments, whereby sand or dust particles become swept up in the rotor outwash. Brownout is characterized by partial or total obscuration of the terrain, which degrades visual cues necessary for hovering and safe landing. Furthermore, the motion of the dust cloud produced during brownout can lead to the pilot experiencing motion cue anomalies such as vection illusions. In this context, the stability and guidance control functions can be intermittently or continuously degraded, potentially leading to undetected surface hazards and obstacles as well as unnoticed drift. Safe and controlled landing in brownout can be achieved using an integrated presentation of LADAR and RADAR imagery and aircraft state symbology. However, though detected by the LADAR and displayed on the sensor image, small obstacles can be difficult to discern from the background so that changes in obstacle elevation may go unnoticed. Moreover, pilot workload associated with tracking the displayed symbology is often so high that the pilot cannot give sufficient attention to the LADAR/RADAR image. This paper documents a simulation evaluating the use of 3D auditory cueing for obstacle avoidance in brownout as a replacement for or compliment to LADAR/RADAR imagery.

3D audio↗

The Science Behind the NASA/NOAA Electronic Theater 2002

Details of the science stories and scientific results behind the Etheater Earth Science Visualizations from the major remote sensing institutions around the country will be explained. The NASA Electronic Theater presents Earth science observations and visualizations in a historical perspective. Fly in from outer space to Temple Square and the University of Utah Campus. Go back to the early weather satellite images from the 1960s see them contrasted with the latest US/Europe/Japan global weather data. See the latest images and image sequences from NASA & NOAA missions like Terra, GOES, NOAA, TRMM, SeaWiFS, Landsat 7 visualized with state-of-the art tools. A similar retrospective of numerical weather models from the 1960s will be compared with the latest "year 2002" high-resolution models. See the inner workings of a powerful hurricane as it is sliced and dissected using the University of Wisconsin Vis-5D interactive visualization system. The largest super computers are now capable of realistic modeling of the global oceans. See ocean vortexes and currents that bring up the nutrients to feed phitoplankton and zooplankton as well as draw the crill fish, whales and fisherman. See the how the ocean blooms in response to these currents and El Nino/La Nina climate regimes. The Internet and networks have appeared while computers and visualizations have vastly improved over the last 40 years. These advances make it possible to present the broad scope and detailed structure of the huge new observed and simulated datasets in a compelling and instructive manner. New visualization tools allow us to interactively roam & zoom through massive global images larger than 40,000 x 20,000 pixels. Powerful movie players allow us to interactively roam, zoom & loop through 4000 x 4000 pixel bigger than HDTV movies of up to 5000 frames. New 3D tools allow highly interactive manipulation of detailed perspective views of many changing model quantities. See the 1m resolution before and after shots of lower Manhattan and the Pentagon after the September 11 disaster as well as shots of Afghanistan from the Space Imaging IKONOS as well as debris plume images from Terra MODIS and SPOT Image. Shown by the SGI-Octane Graphics-Supercomputer are visualizations of hurricanes Michelle 2001, Floyd, Mitch, Fran and Linda. Our visualizations of these storms have been featured on the covers of the National Geographic, Time, Newsweek and Popular Science. Highlights will be shown from the NASA's large collection of High Definition TV (HDTV) visualizations clips New visualizations of a Los Alamos global ocean model, and high-resolution results of a NASA/JPL Atlantic ocean basin model showing currents, and salinity features will be shown. El Nino/La Nina effects on sea surface temperature and sea surface height of the Pacific Ocean will also be shown. The SST simulations will be compared with GOES Gulf Stream animations and ocean productivity observations. Tours will be given of the entire Earth's land surface at 500 m resolution from recently composited Terra MODIS data, Visualizations will be shown from the Earth Science Etheater 2001 recently presented over the last years in New Zealand, Johannesburg, Tokyo, Paris, Munich, Sydney, Melbourne, Honolulu, Washington, New York City, Pasadena, UCAR/Boulder, and Penn State University. The presentation will use a 2-CPU SGI/CRAY Octane Super Graphics workstation with 4 GB RAM and terabyte disk array at 2048 x 768 resolution plus multimedia laptop with three high resolution projectors. Visualizations will also be featured from museum exhibits and presentations including: the Smithsonian Air & Space Museum in Washington, IMAX theater at the Maryland Science Center in Baltimore, the James Lovell Discovery World Science museum in Milwaukee, the American Museum of Natural History (NYC) Hayden Planetarium IMAX theater, etc. The Etheater is sponsored by NASA, NOAA and the American Meteorological Society. This presentation is brought to you by the University of Utah College of Mines and Earth Sciences and, the Utah Museum of Natural History.

Hasler, A. Fritz↗

Analysis of Defects in Metal Additive Manufacturing with Augmented Data Generation

Laser powder bed fusion (LPBF) is a method of additive manufacturing (AM) that selectively melts and fuses together microscopic metallic powder. LPBF offers the benefit of producing custom structures out of high strength metals that can be difficult to fabricate with conventional methods. The challenge of LPBF is that 3D printed structures often have internal pores due to process flaws. Pulsed thermal tomography (PTT) is a method for reconstructing the depth profile of materials, allowing the visualization internal voids in solids. In prior work, we developed a convolutional neural network (CNN) which, having been trained on simulated 2D PTT images of subsurface elliptical defects, was able to classify the semi-major radii, semi-minor radii, and angular orientation of the best-fit ellipses in previously unseen PTT images. The unseen PTT images contained subsurface irregular defect shapes imported from scanning electron microscopy (SEM) images of metallic LPBF-printed specimens. Training the CNN on irregular defect shapes instead of on elliptical shapes would make the resulting classifications more descriptive of actual defect shapes. However, this requires a much higher volume of SEM images of material defects, which are difficult to obtain because of random occurrence of defects in LPBF. To address this challenge, we developed a generative adversarial network (GAN) to augment the existing dataset of SEM defect images. The GAN model is demonstrated to create novel yet realistic defect shapes that can be used as input for simulated PTT images to train CNN.

36 MATERIALS SCIENCE↗

Perceiving environmental structure from optical motion

Generally speaking, one of the most important sources of optical information about environmental structure is known to be the deforming optical patterns produced by the movements of the observer (pilot) or environmental objects. As an observer moves through a rigid environment, the projected optical patterns of environmental objects are systematically transformed according to their orientations and positions in 3D space relative to those of the observer. The detailed characteristics of these deforming optical patterns carry information about the 3D structure of the objects and about their locations and orientations relative to those of the observer. The specific geometrical properties of moving images that may constitute visually detected information about the shapes and locations of environmental objects is examined.

Lappin, Joseph S.↗

J-2X, The Engine of the Future

My project was two-fold, with both parts involving the J-2X Upper Stage engine (which will be used on both the Ares I and V). Mainly, I am responsible for using a program called Iris to create visual represen tations of the rocket engine's telemetry data. Also, my project includes the application of my newly acquired Pro Engineer skills in develo ping a 3D model of the engine's nozzle.

Smith, Gail↗

Virtual Diagnostics Interface (ViDI) for Planning Laser-Based Wind Tunnel Experiments

Virtual Diagnostics Interface (ViDI), originally introduced by Richard Schwartz in 2004 and described again by Alderfer, et. al., in 2007, is an interactive 3D software tool developed at NASA Langley Research Center to serve three main purposes: assist in pre-test planning, enhance post-test image analysis and visualization, and serve as a central location for data storage and distribution.1,2 ViDI is composed of custom-developed software and Autodesk® 3ds Max® as it incorporates Computer Aided Design (CAD) models with the results obtained from optical diagnostics.3 This software tool has proven useful in the field of optical diagnostics where pre-test planning of beam paths, optical elements, and test articles must be carried out to avoid interference, ensure spatial resolution is sufficient, and the camera Field of View (FoV) is adequate for the field of interest. Typically, practical considerations such as the distance a camera is from the region of interest, the angles at which the camera is oriented and issues such as the size of the camera and its sensor and size and focal length lens as well as the path of the laser need to be taken into account to predict a successful measurement. An example application of ViDI is shown in Fig.1 where an experiment to investigate flow separation over the wing of the High Lift Common Research Model (HL-CRM) is currently being planned in the National Transonic Facility (NTF) at NASA Langley Research Center.

virtual diagnostics interface↗