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At least 721 records · Page 40

Clinicopathologic and Transcriptomic Analysis of Radiation-Induced Lung Injury in Nonhuman Primates

Radiation-induced lung injury (RILI) is a progressive condition with an early phase (radiation pneumonitis) and a late phase (lung fibrosis). RILI may occur after partial-body ionizing radiation exposures or internal radioisotope exposure, with wide individual variability in timing and extent of lung injury. This study aimed to provide new insights into the pathogenesis and progression of RILI in the nonhuman primate (NHP) rhesus macaque model.

62 RADIOLOGY AND NUCLEAR MEDICINE↗

Effects of root litter traits on soil organic matter dynamics depend on decay stage and root branching order

Decaying roots contribute disproportionately to soil organic carbon (SOC) stocks in many ecosystems, yet few studies have examined the afterlife effects of root trait variability on the formation, stability and mineralization of SOC. In order to assess how root functional class (absorptive vs. transport) and mycorrhizal association (ectomycorrhizal vs. arbuscular mycorrhizal fungi) affect both formation and loss of SOC, we decayed lower-order absorptive (orders 1–2) and higher-order transport (orders 3–4) roots from six arbuscular mycorrhizal (AM) and six ectomycorrhizal (EcM) associated hardwood tree species in an isotopically distinct soil under laboratory conditions. We found that root litter effects on SOC differed significantly among root functional classes and mycorrhizal types. AM absorptive and transport roots (high in nitrogen and soluble compounds) contributed more to the formation of new mineral-associated organic carbon (MAOC), but also contributed to higher mineralization of native SOC (via priming effects). Moreover, absorptive AM roots formed MAOC gradually and rates saturated, whereas ECM roots formed MAOC more quickly, despite slower decay (via greater formation efficiency). Altogether, these findings demonstrate how different combinations of root traits might contribute to soil C balance, and that failure to account for the chemical and morphological heterogeneity of roots, as well their interactions with microbes over time, may lead to incorrect projections of SOC stocks and turnover.

59 BASIC BIOLOGICAL SCIENCES↗

Automatic detection of cataclysmic variables from SDSS images

Abstract Investigating rare and new objects have always been an important direction in astronomy. Cataclysmic variables (CVs) are ideal and natural celestial bodies for studying the accretion process of semi-detached binaries with accretion processes. However, the sample size of CVs must increase because a lager gap exists between the observational and the theoretical expanding CVs. Astronomy has entered the big data era and can provide massive images containing CV candidates. CVs as a type of faint celestial objects, are highly challenging to be identified directly from images using automatic manners. Deep learning has rapidly developed in intelligent image processing and has been widely applied in some astronomical fields with excellent detection results. YOLOX, as the latest YOLO framework, is advantageous in detecting small and dark targets. This work proposes an improved YOLOX-based framework according to the characteristics of CVs and Sloan Digital Sky Survey (SDSS) photometric images to train and verify the model to realise CV detection. We use the Convolutional Block Attention Module to increase the number of output features with the feature extraction network and adjust the feature fusion network to obtain fused features. Accordingly, the loss function is modified. Experimental results demonstrate that the improved model produces satisfactory results, with average accuracy (mean average Precision at 0.5) of 92.0%, Precision of 92.9%, Recall of 94.3%, and $F1-score$ of 93.6% on the test set. The proposed method can efficiently achieve the identification of CVs in test samples and search for CV candidates in unlabeled images. The image data vastly outnumber the spectra in the SDSS-released data. With supplementary follow-up observations or spectra, the proposed model can help astronomers in seeking and detecting CVs in a new manner to ensure that a more extensive CV catalog can be built. The proposed model may also be applied to the detection of other kinds of celestial objects.

Astronomy & Astrophysics↗

Optimal operation and sizing of pumped thermal energy storage for net benefits maximization

Abstract Current trends in the modern grid are leading to the development and deployment of energy storage to help integrate increasing variable renewable energy sources into the grid. This paper studies a pumped thermal energy storage (PTES) system for multiple grid services including energy arbitrage, frequency regulation, spinning and non‐spinning reserve, and resource adequacy. Optimal dispatch methods are proposed for individual services as well as value stacking from multiple services to maximize the economic benefits. Assessment results demonstrate the superiority of value stacking. Specifically, the study shows the maximum revenue from an individual grid service with a 30‐MWh PTES system was $522,520, while the value stacking could increase the benefits to $678,477. In addition, sensitivity analyses were conducted to explore the cost‐effectiveness of a PTES system with different combinations of power transfer limits and energy capacity. It was found that the power transfer limit had a greater impact than the energy capacity on the benefits. The proposed method could help determine the optimal duration of a future PTES system.

25 ENERGY STORAGE↗

Laser pulse induced second- and third-harmonic generation of gold nanorods with real-time time-dependent density functional tight binding (RT-TDDFTB) method

In this paper, we investigate second- and third-harmonic generation processes in Au nanorod systems using the real-time time-dependent density functional tight binding method. Our study focuses on the computation of nonlinear signals based on the time dependent dipole response induced by linearly polarized laser pulses interacting with nanoparticles. We systematically explore the influence of various laser parameters, including pump intensity, duration, frequency, and polarization directions, on harmonic generation. We demonstrate all the results using Au nanorod dimer systems arranged in end-to-end configurations, and disrupting the spatial symmetry of regular single nanorod systems is crucial for second-harmonic generation processes. Furthermore, we study the impact of nanorod lengths, which lead to variable plasmon energies, on harmonic generation, and estimates of polarizabilities and hyper-polarizabilities are provided.

77 NANOSCIENCE AND NANOTECHNOLOGY↗

Future grid mix impacts on whole-building life cycle assessment

Building construction and operation are a significant contribution to global greenhouse gas emissions, so understanding and mitigating emissions is crucial for reliable and realistic emissions accounting. Whole-building Life Cycle Assessment (WBLCA) is an emissions accounting method that considers lifetime environmental impacts of a building during its construction, operation, and eventual end-of-life. When performing WBLCAs, emission calculations from the building's operation over the entire building lifespan are typically based on today's energy grid mixes. This method does not consider changes or advancements in the clean energy proportion within the grid mix and can over or under-inflate results, skewing the ratio of embodied vs. operational environmental impacts. While a variety of prediction tools estimate what future grid emissions might be, predictions can vary widely. To predict the clean energy ratio within future grid mixes and the potential impact these changes might have on WBLCA, annual data from several existing U.S. grid models was averaged and probabilistic modeling was used to extend the usable projections of shorter forecasts. Results show that clean energy sources will likely continue to increase over time, although the rate of growth varies by model. On average, by 2085, the clean energy penetration of the grid is projected to reach ~81% and renewable energy is projected to reach ~71%, although no widespread consensus is reached. To understand how the future grid mix impacts lifetime building emissions within a WBLCA context, the team analyzed two 2021 IECC-compliant all-electric residential buildings: one built from traditional materials and construction processes and the other built with carbon sequestering materials and modular assembly, with a portion of energy generated on site. The results indicate that a moderate estimate of future electricity grid mixes shows a reduction of yearly operational emissions for traditional residential buildings of 55% between 2025 and 2085, and a corresponding reduction of 48% of total emissions over a 60 year building lifespan. This study offers a nuanced approach to account for the variability of future grid mix models and provides an average trend-line based on a robust collection of scenarios.

Life Cycle Assessment (LCA)↗

Salinity–induced limits to mangrove canopy height

Aim: Mangrove canopy height is a key metric to assess tidal forests' resilience in the face of climate change. In terrestrial forests, tree height is primarily determined by water availability, plant hydraulic design, and disturbance regime. However, the role of water stress remains elusive in tidal environments, where saturated soils are prevalent, and salinity can substantially affect the soil water potential. Location: Global. Time Period: The canopy height dataset provides a global snapshot of the maximum mangrove height geographical distribution for the year 2000. Climate and environmental variables extend over the period 1970–2018. Major Taxa Studied: Mangroves. Methods: We use global observations of maximum canopy height, species richness, air temperature, and seawater salinity—a proxy of soil water salt concentration—to explore the causal link between salinity and mangrove stature. Results: Our findings suggest that salt stress limits mangrove height. High salinity favours more salt-tolerant species, narrowing the spectrum of viable traits. Highly salt-tolerant mangroves have evolved to cope with high salt concentrations in the soil, but this adaptation comes at a cost. They typically have lower rates of photosynthesis and growth, resulting in reduced productivity and smaller stature compared to more salt-sensitive mangrove species. This suggests a causal link between salinity, biodiversity, and tree height, where high salinity selects for more salt-tolerant species that tend to be less productive and shorter. Conclusions: We hypothesize that the salinity-induced limit to mangrove canopy height is the direct result of a reduction of primary productivity, an increment in the risk of xylem cavitation, and an indirect consequence of the decrease in biodiversity. As sea-level rise enhances coastal salinisation, failure to account for these effects can lead to incorrect estimates of future carbon stocks in Tropical coastal ecosystems and endanger preservation efforts.

54 ENVIRONMENTAL SCIENCES↗

Dates and rates of loess deposition and soil formation on the Snake River Plain, Idaho, USA

Loess-paleosol sequences in eolian deposits on the Snake River Plain, Idaho, western United States, preserve records of late Pleistocene to Holocene glacial-interglacial cycles. Here, we examine climate-driven changes in the timing and rate of loess accretion, soil formation, and pedogenic carbonate accumulation in the eastern and central Snake River Plain. High rates of loess deposition often correspond with dry, cold, and windy conditions and/or high sediment supply, while soil formation indicates landscape stability. Optically stimulated luminescence dating of four loess-soil sequences provides a record of the timing of loess deposition, and radiocarbon dating ( 14 C) of soil inorganic carbon provides ages for soil formation and pedogenic carbonate precipitation. On the central Snake River Plain, marine isotope stage (MIS) 3 is marked by loess deposition between ca. 50 ka and 33 ka, and pedogenic carbonate accumulation between ca. 42 ka calibrated years before present (cal. B.P.) and 31 ka cal. B.P. During MIS 2, loess deposition between ca. 21 ka and 15 ka is contemporaneous with pedogenic carbonate precipitation. MIS 2 is characterized by diffuse pedogenic carbonate formation and rapid loess accumulation. Both the eastern and central Snake River Plain study sites experienced high rates of loess deposition during MIS 2; however, the eastern Snake River Plain had almost three times faster rates of loess accumulation (0.56−0.63 m/k.y. from ca. 25 ka to 17 ka) as compared to the central Snake River Plain (0.18−0.26 m/k.y. from ca. 21 ka to 15 ka). During MIS 1, loess deposition on the central Snake River Plain ca. 11 ka was coincident with pedogenic carbonate formation ca. 10 ka cal. B.P. MIS 3 and MIS 1 are characterized by A horizons and well-developed Bk horizons, indicating soil stability and lower rates of loess accumulation during these intervals. Finally, this study highlights the role of late Quaternary−scale climatic variability on rates and amounts of soil inorganic carbon storage.

Geosciences↗

Habitat use by female desert tortoises suggests tradeoffs between resource use and risk avoidance

Animals may select habitat to maximize the benefits of foraging on growth and reproduction, while balancing competing factors like the risk of predation or mortality from other sources. Variation in the distribution of food resources may lead animals to forage at times or in places that carry greater predation risk, with individuals in poor quality habitats expected to take greater risks while foraging. We studied Mojave desert tortoises ( Gopherus agassizii ) in habitats with variable forage availability to determine if risk aversion in their selection of habitat relative was related to abundance of forage. As a measure of risk, we examined tortoise surface activity and mortality. We also compared tortoise body size and body condition between habitats with ample forage plants and those with less forage plants. Tortoises from low forage habitats selected areas where more annual plants were nutritious herbaceous flowering plants but did not favor areas of greater perennial shrub cover that could shelter them or their burrows. In contrast, tortoises occupying high forage habitats showed no preference for forage characteristics, but used burrows associated with more abundant and larger perennial shrubs. Tortoises in high forage habitats were larger and active above ground more often but did not have better body condition. Mortality was four times higher for females occupying low forage habitat than those in high forage habitat. Our results are consistent with the idea that tortoises may minimize mortality risk where food resources are high, but may accept some tradeoff of greater mortality risk in order to forage optimally when food resources are limiting.

59 BASIC BIOLOGICAL SCIENCES↗

Microwave-Assisted Catalytic Gasification of Various Biomass with Mixed Plastic Wastes for H2-Rich Syngas Production

Co-gasification of plastics mixture with biomass has shown synergistic effects in Microwave (MW) reactor resulting in higher H2-rich syngas yield and reduced char/tar. This study investigates a microwave-assisted catalytic gasification of variable feedstock such as various biomass blended with mixed plastics waste using Fe-based catalyst to produce H2 rich syngas as a primary product.

catalysis, biomass gasification↗

Integrating Experiments, Simulations, and Artificial Intelligence to Accelerate the Discovery of High-Performance Green Composites

The imperative for incorporating greener materials into the aerospace industry necessitates addressing significant challenges associated with the microstructural variability exhibited by recycled and sustainable feedstocks. In this study, we propose an integrated methodology that combines experimental investigations, finite element analysis, and artificial intelligence to develop sustainable composites with consistent properties. Our approach utilizes a pipeline comprising an automated mechanical tester, a finite element method simulator, and a convolutional neural network predictor to identify and optimize fabrication parameters for achieving desired mechanical characteristics in composites. By employing a nested-loop pipeline, our methodology improves sample efficiency, accuracy, and effectively bridges the gap between simulations and real-world performance. This unique methodology offers a promising avenue for facilitating the adoption of aerospace-appropriate green composites.

Athanasiou, Christos↗

New Insights Into Lignification via Network and Multi-Omics Analyses of Arogenate Dehydratase Knock-Out Mutants in Arabidopsis thaliana

Multiple Arabidopsis arogenate dehydratase (ADT) knock-out (KO) mutants, with phenotypes having variable lignin levels (up to circa 70% reduction), were studied to investigate how differential reductions in ADTs perturb its overall plant systems biology. Integrated "omics" analyses (metabolome, transcriptome, and proteome) of wild type (WT), single and multiple ADT KO lines were conducted. Transcriptome and proteome data were collapsed into gene ortholog (GO) data, with this allowing for enzymatic reaction and metabolome cross-comparisons to uncover dominant or likely metabolic biosynthesis reactions affected. Network analysis of enzymes-highly correlated to stem lignin levels-deduced the involvement of novel putative lignin related proteins or processes. These included those associated with ribosomes, the spliceosome, mRNA transport, aminoacyl tRNA biosynthesis, and phosphorylation. While prior work helped explain lignin biosynthesis regulation at the transcriptional level, our data here provide support for a new hypothesis that there are additional post-transcriptional and translational level processes that need to be considered. These findings are anticipated to lead to development of more accurate depictions of lignin/phenylpropanoid biosynthesis models in situ, with new protein targets identified for further biochemical analysis and/or plant bioengineering. Additionally, using KEGG defined functional categorization of proteomics and transcriptomics analyses, we detected significant changes to glucosinolate, a-linolenic acid, nitrogen, carotenoid, aromatic amino acid, phenylpropanoid, and photosynthesis-related metabolic pathways in ADT KO mutants. Metabolomics results also revealed that putative carotenoid and galactolipid levels were generally increased in amount, whereas many glucosinolates and phenylpropanoids (including flavonoids and lignans) were decreased in the KO mutants.

Arabidopsis, arogenate dehydratases, lignin, multi↗

Comparative Performance of Gaussian Plume and Backward Lagrangian Stochastic Models for Near-Field Methane Emission Estimation Using a Single Controlled Release Experiment

Methane (CH 4 ) is a major component of natural gas and a potent greenhouse gas. Increasing atmospheric methane concentrations are attributed to emissive anthropogenic activities by an average of 13 ppb per yr since 2020 and are linked to a changing global climate. Mitigating CH 4 emissions from oil and gas production sites has recently become a target to reduce overall greenhouse gas emissions; however, monitoring the efficacy of mitigation strategies depends on accurate quantification of CH 4 emissions at the facility-level. Near-field quantification of methane (CH 4 ) emissions from oil and gas (O&G) facilities remains challenging due to the effects of atmospheric variability and sensor configuration on atmospheric dispersion models. This study evaluates the performance of two atmospheric dispersion models, the Gaussian plume (GP) and backward Lagrangian stochastic (bLS), by comparing calculated CH 4 emissions to controlled single-point emissions between 0.4 and 5.2 kg CH 4 h −1 . Emissions were calculated by both models using 121 individual sets of measurements comprising five-minute averaged downwind methane mixing ratios and matching meteorological data. The comparison shows that the bLS approach achieved a higher proportion of emission estimates within a factor of two (FAC2) of the known emission rates compared to the GP approach. The emissions calculated by the bLS model also had a lower multiplicative error and reduced bias relative to GP. Other error-based metrics further confirmed the bLS model performed better, as it yielded lower RMSE and MAE than GP. Statistical analysis of the emission data shows that the lateral and vertical alignment of the source and the sensor plays a critical role in emission estimations, as measurements made closer to the plume centerline and at a distance between 40 and 80 m downwind yielded the best FAC2 agreement. High wind meander degraded the ability of both approaches to generate representative emissions, particularly with the GP approach, as it violates the modeling approach’s assumption of steady-state emissions. Data suggest emissions calculated by the bLS model are comprehensively in better agreement, but the computational demands of the modeling approach and integration into fenceline systems limit real-time applicability. While these results provide insight into model performance under controlled near-field conditions, their applicability to more complex or heterogeneous oil and gas production environments (e.g., the regions Marcellus or Unita Basins) remains limited and uncertain.

gaussian plume↗

What is Important? Morphological Asymmetries are Useful Predictors of Star Formation Rates of Star-forming Galaxies in SDSS Stripe 82

The morphology and structure of galaxies reflect their star formation and assembly histories. We use the framework of mutual information (MI) to quantify the interdependence among several structural variables and to rank them according to their relevance for predicting the specific star formation rate (SSFR) by comparing the MI of the predictor variables with the SSFR and penalizing variables that are redundant. We apply this framework to study ~3700 face-on star-forming galaxies (SFGs) with varying degrees of bulge dominance and central concentration and with stellar mass $M$ * ≈ 10 9 $M$ ⊙ at redshift $z$ = 0.02–0.12. We use the Sloan Digital Sky Survey (SDSS) Stripe 82 deep $i$-band imaging data, which improve measurements of asymmetry and bulge dominance indicators. We find that star-forming galaxies are a multiparameter family. In addition to $M$ * , asymmetry emerges as the most powerful predictor of SSFR residuals of SFGs, followed by bulge prominence/concentration. Star-forming galaxies with higher asymmetry and stronger bulges have higher SSFR at a given $M$ * . In conclusion, the asymmetry reflects both irregular spiral arms and lopsidedness in seemingly isolated SFGs and structural perturbations by galaxy interactions or mergers.

79 ASTRONOMY AND ASTROPHYSICS↗

Whole-organism 3D quantitative characterization of zebrafish melanin by silver deposition micro-CT

We previously described X-ray histotomography, a high-resolution, non-destructive form of X-ray microtomography (micro-CT) imaging customized for three-dimensional (3D), digital histology, allowing quantitative, volumetric tissue and organismal phenotyping (Ding et al., 2019). Here, we have combined micro-CT with a novel application of ionic silver staining to characterize melanin distribution in whole zebrafish larvae. The resulting images enabled whole-body, computational analyses of regional melanin content and morphology. Normalized micro-CT reconstructions of silver-stained fish consistently reproduced pigment patterns seen by light microscopy, and further allowed direct quantitative comparisons of melanin content across wild-type and mutant samples, including subtle phenotypes not previously noticed. Silver staining of melanin for micro-CT provides proof-of-principle for whole-body, 3D computational phenomic analysis of a specific cell type at cellular resolution, with potential applications in other model organisms and melanocytic neoplasms. Advances such as this in whole-organism, high-resolution phenotyping provide superior context for studying the phenotypic effects of genetic, disease, and environmental variables.

59 BASIC BIOLOGICAL SCIENCES↗

Techno-Economic Viability of Flexible Dispatch of Unconventional Geothermal Systems

Flexible geothermal operations could boost project returns through the allocation of improved power purchase agreements and/or exploitation of power price arbitrage opportunities. In this study, we investigated the techno-economic feasibility of variable flow rate control and time-of-day pricing in closed-loop geothermal systems. We considered U-shaped multilateral system configurations and modeled a variety of technical system parameters. These designs were simulated using a slender-body theory (SBT) model for transient heat transfer and fluid flow. This subsurface model was integrated into the flexible geothermal economic model (FGEM) tool to evaluate the overall flexible geothermal system techno-economics. Future hourly ambient temperature conditions were based on the Sup3rCC dataset. Published datasets were used for future hourly wholesale electricity prices. We analyzed four operating strategies: 1) baseload operation, 2) seasonal dispatch (high flow rate during summer and nominal flow rate during the rest of the year), 3) net generation maximization by varying flow rate to maximize net power output, and 4) revenue maximization by varying flow rate to maximize revenue. We ran all four scenarios for a multiloop configuration with 12 lateral passes, 7-km vertical depth and 87-km total drilling length. Furthermore, we assumed a 60 degrees C/km geothermal gradient and ambient temperature and wholesale electricity prices for New Mexico as a typical state location. The nominal flow rate was set to 80 kg/s. When considering drilling costs of $1,000/m and a discount rate of 7%, the generation maximization scenario resulted in the lowest levelized cost of electricity (LCOE) of ~$150/MWh. When considering project return on investment (ROI), defined as lifetime net income divided by upfront capital costs, all flexible operation scenarios performed better than the base case scenario. The highest ROI of 80% was obtained with the revenue maximization scenario. With drilling costs of $200/m and a discount rate of 5%, the generation maximization scenario resulted in LCOE of $49/MWh.

flexible geothermal↗

Modulation of springtime surface sensible heating over the Tibetan Plateau on the interannual variability of East Asian dust cycle

Previous observational evidence and numerical simulations have revealed that the surface sensible heating in spring (March–April–May, MAM) over the Tibetan Plateau (TPSH) can affect the Asian regional hydrological cycle, surface energy balance, and climate through altering atmospheric heat source of the Tibetan Plateau (TP). This study aims to investigate the impacts of MAM TPSH on the interannual variability of East Asian dust cycle by using CAM4-BAM (version 4 of the Community Atmosphere Model coupled to a bulk aerosol model), MERRA-2 (version 2 of the Modern-Era Retrospective analysis for Research and Applications) surface dust concentration, and TPSH measurements. Our simulations show that the surface dust concentrations over the East Asian (EA) dust source region and over the northwestern Pacific (NP) in MAM are significantly positively correlated with TPSH, with regionally averaged correlation coefficients of 0.49 for EA and 0.44 for NP. Similar positive correlations are also shown between the MAM TPSH measurements averaged over the 73 observation sites and the surface dust concentration from MERRA-2. Simulation-based comparisons between strongest and weakest TPSH years reveal that, the MAM surface dust concentration in the strongest TPSH years increases with relative differences of 13.1 % over EA and 36.9 % over NP. These corresponding differences are found in MERRA-2 with 22.9 % and 13.3 % over EA and NP, respectively. Further simulated results show that the processes of whole dust cycles (e.g., dust loading, emission, and transport, as well as dust deposition) are also significantly enhanced during the strongest TPSH years over EA and NP. Through enhancing the TP heat source, stronger TPSH in MAM generates an anticyclonic anomaly in middle and upper troposphere over the TP and over the downstream Pacific region, respectively. These atmospheric circulation anomalies induced by the increased TPSH result in increasing the westerly winds over both EA and NP, which in turn increases dust emissions over the dust source, and dust transport over these two regions, as well as the regional dust cycles. These results suggest that addressing the East Asian dust changes in the future climates requires considering not only increasing greenhouse gas emissions but also the variations of the TP's heat source under global warming.

54 ENVIRONMENTAL SCIENCES↗

Blockchain-Enabled Cyber-Secure Microgrid Control Using Consensus Algorithm

This paper proposes a distributed control method based on a consensus algorithm for distributed energy resources (DERs) using blockchain as a secure communication medium for cyber resilience. Each DER communicates with a local blockchain server that is maintained by the distributed ledger technology to allow for securely sharing local measurements among neighbouring assets to achieve the global control objectives, i.e., voltage and frequency regulation as well as accurate power sharing among the DERs, including collective grid-forming capability. To prove that the distributed control can retain system stability under a blockchain-induced variable communication delay, Lyapunov function-based stability analysis is carried out. This paper demonstrates the concept on an 11-bus test case developed in MATLAB Simulink, which has been modified from the IEEE 9-bus test case, to study dynamic operations of the five inverter-based DERs working with a blockchain-induced variable delay. The results validate the superior performance of the proposed control method, compared to heavily compromised operations of the other test cases without the security measure, affected by heavy communication delays and communication interruptions.

blockchains↗