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Root identification in minirhizotron imagery with multiple instance learning

In this study, multiple instance learning (MIL) algorithms to automatically perform root detection and segmentation in minirhizotron imagery using only image-level labels are proposed. Root and soil characteristics vary from location to location, and thus, supervised machine learning approaches that are trained with local data provide the best ability to identify and segment roots in minirhizotron imagery. However, labeling roots for training data (or otherwise) is an extremely tedious and time-consuming task. This paper aims to address this problem by labeling data at the image level (rather than the individual root or root pixel level) and train algorithms to perform individual root pixel level segmentation using MIL strategies. Three MIL methods (multiple instance adaptive cosine coherence estimator, multiple instance support vector machine, multiple instance learning with randomized trees) were applied to root detection and compared to non-MIL approaches. The results show that MIL methods improve root segmentation in challenging minirhizotron imagery and reduce the labeling burden. In our results, multiple instance support vector machine outperformed other methods. The multiple instance adaptive cosine coherence estimator algorithm was a close second with an added advantage that it learned an interpretable root signature which identified the traits used to distinguish roots from soil and did not require parameter selection.

59 BASIC BIOLOGICAL SCIENCES↗

Developing ML/AI Methods for High-Throughput Characterization of Multiple-Sensor Streams of Tokamak Dynamics for High-Speed Control (Final Report)

This project evaluated and developed new mathematical and algorithmic techniques capable of handling (in real-time) the growing amounts of data generated by modern fusion research. While existing numerical linear algebra (NLA) methods provide the backbone to classical data analysis and algorithms, these methods fundamentally do not port to distributed architectures nor do they allow low-latency data reduction for control. Motivated by the needs for modern fusion reactors, this project explored and implemented new numerical methods to characterize plasma dynamics, respond in real-time to discharge evolution, and to process massive-scale data accurately and rapidly more fully. This project links expertise in multiple-sensor diagnostics of tokamak plasma dynamics from Columbia University’s Plasma Physics Laboratory with expertise in massive-scale data reduction and extreme data control algorithms at Columbia University’s Data Science Institute. This interdisciplinary project (i) applied machine learning methods, (ii) implemented a properly-trained neural-network for very fast processing of high-speed plasma videography, and (ii) developed the applied mathematical methods, based on randomized-NLA (rNLA) routines, for data analysis, reduction, and real-time control. The Columbia University High Beta Tokamak-Extended Pulse (HBT-EP) facility provided data to test new algorithms and partnership with Columbia University's Data Sciences Institute evaluated the broader use of new algorithms for many challenging control applications.

70 PLASMA PHYSICS AND FUSION TECHNOLOGY↗

Spreader-Bar Radiation Detection System Enhancements: A Modeling and Simulation Study

An investigation of radiation detectors on crane-mounted platforms was performed to understand the limitations and optimal capability of these types of systems. Crane-mounted systems are primarily focused on crane-mounted radiation detector systems, where the detectors are mounted on a spreader-bar platform. Spreader bars are attached with cables to a crane at seaports to load and unload containers from cargo ships. The bars can spread from 20 feet to 53 feet using hydraulics, allowing a single bar to move a variety of container lengths. Spreader-bars are also used on straddle carriers, which move containers around the laydown yard in the port. Spreader bar radiation detection (SBRD) systems are commercially available from at least two companies. These systems employ a set of spectroscopic sensors placed on the underside of a gantry crane and held near the top of a cargo container for detection. These systems have been previously tested and some issues and limitations observed. Radiation detectors mounted on spreader-bars are single sided systems (observing cargo only from the top) and it is therefore challenging to obtain the same sensitivity as double-sided systems (for example, portal monitors) especially when considering the possible amounts of intervening cargo that could be present. The approximately exponential attenuation of gamma rays in intervening dense cargo presents an inherent limitation to detection. However, SBRD systems hold detectors closer to the container, have a longer dwell time, and may have lower background (over the ship); all of these aspects help mitigate the single-sided issue. In addition, there are operational considerations that make spreader-bar radiation systems attractive. These include scanning for radiation during other operations (loading, unloading or container movement) which minimizes additional time for scanning, incorporating the radiation detection into existing equipment to minimize initial cost, and in the case of ship unloading, scanning the containers before reaching the laydown yard. This study is focused on researching optimized configurations of SBRD systems, including number of detectors, locations, and best use of detector data, to determine a reasonable limit on the capability of these types of systems. The results will help support decisions on where and how these systems might be effectively deployed, and could be used for future specification development for SBRD acquisition. The next phase of this research and investigation into SBRD systems and quantification of the possible improved capability with an enhanced SBRD is the focus of this report. Supporting this investigation, detailed models of an enhanced SBRD system were created using a 3D radiation transport code, and models were run to simulate the data from sources and background for a realistic cargo-loading port environment. The enhanced SBRD had increased detector material (numbers of detectors) compared to the commercial systems, with a distribution providing more uniform coverage. Measurements using small industrial sources were made with an enhanced SBRD system developed by Sandia National Laboratory to support model validation to establish credibility for the simulations of these threat and background scenarios. A significant simulation effort was undertaken to simulate sources of interest within a 40-foot cargo container. In order to estimate the performance of a generalized SBRD system in scenarios including background and cargo, a highly enriched uranium (HEU) test source (with 3x10 -8 232 U by weight) within a wood cargo model was simulated for a 40-foot cargo container. This source was placed at a variety of locations, and the flux from the source was multiplied as necessary to create estimated minimal detectable quantities (MDQ) figures for various quantities of HEU. Simulated data sets were produced corresponding to a complete container offloading scenario for a large number of statistical realizations. Significant work was performed on both the algorithm development and the container cargo distributions entering the US, and the result of this modeling, validation, and simulation effort was a set of estimates of the performance of a variety of radiation detection algorithms in this cargo-screening environment. In the case of algorithms, a variety of contemporary radiation detection and identification approaches were employed, and the optimal approaches to selecting time and location subsets of detector data were explored. In all cases, algorithm performance was compared, and the best approaches were suggested along with the best expected performance from the enhanced SBRD. In general, template-matching schemes employing a limited set of regression parameters tend to provide best results. The improvements of an enhanced SBRD with increased detector material and improved algorithms result in an effective MDQ of 10 kg of HEU in ~50 percent of the imported cargo in 40-foot containers, assuming a random source location. This is approximately two times the capability of the estimated performance of the commercial systems. For an MDQ of the 10 kg HEU source located in the worst location (bottom of the 40-foot container), the volume of cargo scanned drops to 10% for the enhanced SBRD, again a factor of two or more larger than the commercial systems. Enhancing the SBRD systems by adding more detectors, providing a more uniform coverage, and incorporating more advanced algorithms will result in a significant increase in capability. Although this investigation provided some indication of the performance capabilities of an enhanced SBRD system, additional work is needed to estimate the capability for other container configurations, such as the 20 and 45 foot containers. Since the 20-foot container weight limit is similar to the 40-foot, more dense cargo is typically shipped in 20-foot containers. This will result in a smaller percentage of cargo scanned for the 20-foot containers (for a particular source quantity) compared to the 40-foot containers. In addition to other configuration, other source material needs to be investigated to understand the capabilities for the entire threat space, where only HEU is considered in this work.

crane-mounted↗

The virialization density of peaks with general density profiles under spherical collapse

We calculate the non-linear virialization density, Δ{sub c}, of halos under spherical collapse from peaks with an arbitrary initial and final density profile. This is in contrast to the standard calculation of Δ{sub c} which assumes top-hat profiles. Given our formalism, the non-linear halo density can be calculated once the shape of the initial peak's density profile and the shape of the virialized halo's profile are provided. We solve for Δ{sub c} for halos in an Einstein de-Sitter and a ΛCDM universe. As examples, we consider power-law initial profiles as well as spherically averaged peak profiles calculated from the statistics of a Gaussian random field. We find that, depending on the profiles used, Δ{sub c} is smaller by a factor of a few to as much as a factor of 10 as compared to the density given by the standard calculation ( ≈ 200). Using our results, we show that, for halo finding algorithms that identify halos through an over-density threshold, the halo mass function measured from cosmological simulations can be enhanced at all halo masses by a factor of a few. This difference could be important when using numerical simulations to assess the validity of analytic models of the halo mass function.

79 ASTRONOMY AND ASTROPHYSICS↗

SU-C-BRA-04: Automated Segmentation of Head-And-Neck CT Images for Radiotherapy Treatment Planning Via Multi-Atlas Machine Learning (MAML)

Purpose: Accurate image segmentation is a crucial step during image guided radiation therapy. This work proposes multi-atlas machine learning (MAML) algorithm for automated segmentation of head-and-neck CT images. Methods: As the first step, the algorithm utilizes normalized mutual information as similarity metric, affine registration combined with multiresolution B-Spline registration, and then fuses together using the label fusion strategy via Plastimatch. As the second step, the following feature selection strategy is proposed to extract five feature components from reference or atlas images: intensity (I), distance map (D), box (B), center of gravity (C) and stable point (S). The box feature B is novel. It describes a relative position from each point to minimum inscribed rectangle of ROI. The center-of-gravity feature C is the 3D Euclidean distance from a sample point to the ROI center of gravity, and then S is the distance of the sample point to the landmarks. Then, we adopt random forest (RF) in Scikit-learn, a Python module integrating a wide range of state-of-the-art machine learning algorithms as classifier. Different feature and atlas strategies are used for different ROIs for improved performance, such as multi-atlas strategy with reference box for brainstem, and single-atlas strategy with reference landmark for optic chiasm. Results: The algorithm was validated on a set of 33 CT images with manual contours using a leave-one-out cross-validation strategy. Dice similarity coefficients between manual contours and automated contours were calculated: the proposed MAML method had an improvement from 0.79 to 0.83 for brainstem and 0.11 to 0.52 for optic chiasm with respect to multi-atlas segmentation method (MA). Conclusion: A MAML method has been proposed for automated segmentation of head-and-neck CT images with improved performance. It provides the comparable result in brainstem and the improved result in optic chiasm compared with MA. Xuhua Ren and Hao Gao were partially supported by the NSFC (#11405105), the 973 Program (#2015CB856000), and the Shanghai Pujiang Talent Program (#14PJ1404500).

60 APPLIED LIFE SCIENCES↗

Detection of surface water temperature variations of Mongolian lakes benefiting from the spatially and temporally gap-filled MODIS data

Lakes provide critical water resources for human activities and ecosystems, particularly in the Mongolian Plateau (MP), which is characterized by a dry climate and a harsh environment. As a region that is sensitive to anthropogenic warming, tracking lake surface water temperature (LSWT) changes in Mongolian lakes is crucial for understanding the consequences of a warming climate on lake ecosystems. However, the long-term monitoring of LSWT is restricted by the spatiotemporal gaps in the raw imagery of remote sensing-based land surface temperature (LST), e.g., the commonly used Moderate Resolution Imaging Spectroradiometer (MODIS) LST products. This study applied an improved gap-filling method by utilizing the discrete cosine transform-based penalized least squares (DCT-PLS) strategy in the spatial domain combined with the linear interpolation (LI) algorithm in the temporal domain. The method was applied to fill gaps in the LSWT imagery of 12 representative lakes across MP. The randomly sampled high-quality MODIS LSWT values in the spatial and temporal domains were excavated as false data gaps and considered “virtual true” validation datasets. The spatial validation results showed that the estimated LSWT for all the lake cases were comparable with the “virtual true” LSWT values, with the average values of the coefficient of determination, mean absolute error, mean square error, and root mean square error being 0.98, 0.38 °C, 0.45 °C, and 0.59 °C, respectively. Meanwhile, the error of nighttime LSWT results was relatively lower than that of daytime LSWT. For temporal interpolation validation, the LI algorithm exhibited relatively better performance and could more objectively indicate the variation in LSWT. Benefiting from the spatially and temporally well-constrained data, we analyzed the interannual and intra-annual change characteristics of the LSWTs of the 12 lakes. The long-term variations of annual and seasonal mean LSWTs in the 12 selected lakes exhibited no evident trends in 2000–2020, while presented apparent interannual fluctuations. The slight changes in the average LSWTs of the 12 selected lakes were in excellent synchronization with the surrounding LST derived from the reanalysis datasets, confirming the widely reported phenomenon of “global warming hiatus” that occurred in the early 21st century. This study improves the understanding of the LSWT variations in Mongolian lakes in response to global climate change. It has the potential to provide an effective approach for monitoring LSWT changes in other large-scale studies.

54 ENVIRONMENTAL SCIENCES↗

Discontinuous finite element solution of the radiation diffusion equation on arbitrary polygonal meshes and locally adapted quadrilateral grids

In this paper, we propose a piece-wise linear discontinuous (PWLD) finite element discretization of the diffusion equation for arbitrary polygonal meshes. It is based on the standard diffusion form and uses the symmetric interior penalty technique, which yields a symmetric positive definite linear system matrix. A preconditioned conjugate gradient algorithm is employed to solve the linear system. Piece-wise linear approximations also allow a straightforward implementation of local mesh adaptation by allowing unrefined cells to be interpreted as polygons with an increased number of vertices. Several test cases, taken from the literature on the discretization of the radiation diffusion equation, are presented: random, sinusoidal, Shestakov, and Z meshes are used. The last numerical example demonstrates the application of the PWLD discretization to adaptive mesh refinement.

71 CLASSICAL AND QUANTUM MECHANICS, GENERAL PHYSIC↗

Development and Validation of Quantitative Model-Based Image Reconstruction for NDE of Reinforced Steel-Lined Concrete Structures: Kal-El FY 2020

This project studied the capabilities of Model-Based Image Reconstruction (MBIR) and Machine Learning (ML) algorithms in the imaging and estimation of rebar corrosion from ultrasound signals. The application was challenging due to the introduction of a steel liner between the sensor and the concrete containing the rebar. The study focused in a synthetic specimen with a 6.35 mm thick steel liner, and a 19.05 mm diameter rebar at a depth of 44.5 mm and with four levels of corrosion; 0%, 20%, 50%, and 100% corrosion level. The corrosion was applied uniformly around the rebar, generating a ring in the perimeter of the rebar with different acoustic density. In order to generate a realistic synthetic dataset, we added random texture to the concrete of the synthetic specimens. This texture will mimic the variations encountered in real concrete specimens.We adapted our MBIR algorithm for the application and enhanced the algorithm to integrate in the physical model known specimen features, such as the steel liner thickness. The new MBIR method was able to cancel out reverberation from the steel liner and properly image the rebar. In particular, corrosion for the 50% and 100% cases were easily visible and quantitative metrics showed a slight separation for the 0% and 20% levels. The quantitative results were in agreement with the qualitative assessment. We also developed a ML XGBoost model to estimate corrosion level from the ultrasound signals. By combining the ML method with MBIR, we can pinpoint in the ultrasound signals the section that corresponds to the echoes from the rebar. The extract signals are processed by the XGBoost model for prediction. From each system scan, we obtain 15 predictions. The median prediction value is used as the final prediction. The True Acceptance Rate for the method is over 99%.

36 MATERIALS SCIENCE↗

Extreme-Scale Bayesian Inference for Uncertainty Quantification of Complex Simulations

Uncertainty quantification (UQ)—that is, quantifying uncertainties in complex mathematical models and their large-scale computational implementations—is widely viewed as one of the outstanding challenges facing the field of CS&E over the coming decade. The EUREKA project set to address the most difficult class of UQ problems: those for which both the underlying PDE model as well as the uncertain parameters are of extreme scale. In the project we worked on these extreme-scale challenges in the following four areas: 1. Scalable parallel algorithms for sampling and characterizing the posterior distribution that exploit the structure of the underlying PDEs and parameter-to-observable map. These include structure-exploiting versions of the randomized maximum likelihood method, which aims to overcome the intractability of employing conventional MCMC methods for solving extreme-scale Bayesian inversion problems by appealing to and adapting ideas from large-scale PDE-constrained optimization, which have been very successful at exploring high-dimensional spaces. 2. Scalable parallel algorithms for construction of prior and likelihood functions based on learning methods and non-parametric density estimation. Constructing problem-specific priors remains a critical challenge in Bayesian inference, and more so in high dimensions. Another challenge is construction of likelihood functions that capture unmodeled couplings between observations and parameters. We will create parallel algorithms for non-parametric density estimation using high dimensional N-body methods and combine them with supervised learning techniques for the construction of priors and likelihood functions. 3. Bayesian inadequacy models, which augment physics models with stochastic models that represent their imperfections. The success of the Bayesian inference framework depends on the ability to represent the uncertainty due to imperfections of the mathematical model of the phenomena of interest. This is a central challenge in UQ, especially for large-scale models. We propose to develop the mathematical tools to address these challenges in the context of extreme-scale problems. 4. Parallel scalable algorithms for Bayesian optimal experimental design (OED). Bayesian inversion yields quantified uncertainties in the model parameters, which can be propagated forward through the model to yield uncertainty in outputs of interest. This opens the way for designing new experiments to reduce the uncertainties in the model parameters and model predictions. Such experimental design problems have been intractable for large-scale problems using conventional methods; we will create OED algorithms that exploit the structure of the PDE model and the parameter-to-output map to overcome these challenges. Parallel algorithms for these four problems were created, analyzed, prototyped, implemented, tuned, and scaled up for leading-edge supercomputers, including UT-Austin’s own 10 petaflops Stampede system, ANL’s Mira system, and ORNL’s Titan system. While our focus is on fundamental mathematical/computational methods and algorithms, we will assess our methods on model problems derived from several DOE mission applications, including multiscale mechanics and ice sheet dynamics.

97 MATHEMATICS AND COMPUTING↗

Classical combinatorial optimization scaling for random Ising models on 2D heavy-hex graphs

Motivated by near term quantum computing hardware limitations, combinatorial optimization problems that can be addressed by current quantum algorithms and noisy hardware with little or no overhead are used to probe capabilities of quantum algorithms such as the quantum approximate optimization algorithm. In this study, a specific class of near term quantum computing hardware defined combinatorial optimization problems, Ising models on heavy-hex graphs both with and without geometrically local cubic terms, are examined for their classical computational hardness via empirical computation time scaling quantification. Specifically the time-to-solution (TTS) metric using the classical heuristic simulated annealing is measured for finding optimal variable assignments (ground states), as well as the time required for the optimization software Gurobi to find an optimal variable assignment. Because of the sparsity of these Ising models, the classical algorithms are able to find optimal solutions efficiently even for large instances (i.e. 100 000 spin variables). The Ising models both with and without geometrically local cubic terms exhibit average-case linear-time or weakly quadratic scaling when solved exactly using Gurobi, and the Ising models with no cubic terms show evidence of exponential-time TTS scaling when sampled using simulated annealing. These findings point to the necessity of developing and testing more complex, namely more densely connected, optimization problems in order for quantum computing to ever have a practical advantage over classical computing. Our results are another illustration that different classical algorithms can indeed have exponentially different running times, thus making the identification of the best practical classical technique important in any quantum computing vs. classical computing comparison.

71 CLASSICAL AND QUANTUM MECHANICS, GENERAL PHYSIC↗

Computational and compressive imaging via additively manufactured random optical element

Here, the ubiquity of computer processing power has enabled new imaging architectures that significantly depart from traditional imaging devices. Imaging systems with deeply enmeshed algorithmic elements are known as computational imaging systems, and can take unconventional physical forms compared to photographic systems. We report on the development and evaluation of a lensless imaging system utilizing an additively manufactured transparent optical element capable of producing image reconstructions after a calibration process. A generalized metric for image quality is presented and used to evaluate system performance as a function of total samples used to calibrate and test.

97 MATHEMATICS AND COMPUTING↗

A Framework to Analyze the Performance of Load Balancing Schemes for Ensembles of Stochastic Simulations

Ensembles of simulations are employed to estimate the statistics of possible future states of a system, and are widely used in important applications such as climate change and biological modeling. Ensembles of runs can naturally be executed in parallel. However, when the CPU times of individual simulations vary considerably, a simple strategy of assigning an equal number of tasks per processor can lead to serious work imbalances and low parallel efficiency. This paper presents a new probabilistic framework to analyze the performance of dynamic load balancing algorithms for ensembles of simulations where many tasks are mapped onto each processor, and where the individual compute times vary considerably among tasks. Four load balancing strategies are discussed: most-dividing, all-redistribution, random-polling, and neighbor-redistribution. Simulation results with a stochastic budding yeast cell cycle model are consistent with the theoretical analysis. It is especially significant that there is a provable global decrease in load imbalance for the local rebalancing algorithms due to scalability concerns for the global rebalancing algorithms. The overall simulation time is reduced by up to 25 %, and the total processor idle time by 85 %.

ALGORITHMS↗

Global sensitivity analysis in stochastic simulators of uncertain reaction networks

Stochastic models of chemical systems are often subjected to uncertainties in kinetic parameters in addition to the inherent random nature of their dynamics. Uncertainty quantification in such systems is generally achieved by means of sensitivity analyses in which one characterizes the variability with the uncertain kinetic parameters of the first statistical moments of model predictions. In this work, we propose an original global sensitivity analysis method where the parametric and inherent variability sources are both treated through Sobol’s decomposition of the variance into contributions from arbitrary subset of uncertain parameters and stochastic reaction channels. The conceptual development only assumes that the inherent and parametric sources are independent, and considers the Poisson processes in the random-time-change representation of the state dynamics as the fundamental objects governing the inherent stochasticity. Here, a sampling algorithm is proposed to perform the global sensitivity analysis, and to estimate the partial variances and sensitivity indices characterizing the importance of the various sources of variability and their interactions. The birth-death and Schlögl models are used to illustrate both the implementation of the algorithm and the richness of the proposed analysis method. The output of the proposed sensitivity analysis is also contrasted with a local derivative-based sensitivity analysis method classically used for this type of systems.

97 MATHEMATICS AND COMPUTING↗

A novel data gaps filling method for solar PV output forecasting

This study proposes a modified gaps filling method, expanding the column mean imputation method and evaluated using randomly generated missing values comprising 5%, 10%, 15%, and 20% of the original data on power output. The XGBoost algorithm was implemented as a forecasting model using the original and processed datasets and two sources of solar radiation data, namely, Shortwave Radiation (SWR) from Advanced Himawari Imager 8 (AHI-8) and Surface Solar Radiation Downward (SSRD) from ERA5 global reanalysis data. Further, the accuracy of the two sets of forecasted power output was evaluated using Root Mean Square Error (RMSE) and Mean Absolute Error (MAE). Results show that by applying the proposed gap filling method and using SWR in forecasting solar photovoltaic (PV) output, the improvement in the RMSE and MAE values range from 12.52% to 24.30% and from 21.10% to 31.31%, respectively. Meanwhile, using SSRD, the improvement in the RMSE values range from 14.01% to 28.54% and MAE values from 22.39% to 35.53%. To further evaluate the accuracy of the proposed gap-filling method, the proposed method could be validated using different datasets and other forecasting methods. Future studies could also consider applying the said method to datasets with data gaps higher than 20%.

Energy & Fuels↗

Gravitational encounters and the evolution of galactic nuclei. II. Classical and resonant relaxation

Direct numerical integrations of the Fokker–Planck equation in energy-angular momentum space are carried out for stars orbiting a supermassive black hole (SBH) at the center of a galaxy. The algorithm, which was described in detail in an earlier paper, includes diffusion coefficients that describe the effects of both random (“classical”) and correlated (“resonant”) encounters. Steady-state solutions are similar to the Bahcall–Wolf solution, n(r)∝r{sup −7/4}, but are modified at small radii due to the higher rate of diffusion in angular momentum, which results in a low-density core. The core radius is a few percent of the influence radius of the SBH. The corresponding phase-space density f(E,L) drops nearly to zero at low energies, implying almost no stars on tightly bound orbits about the SBH. Steady-state rates of stellar disruption are presented, and a simple analytic expression is found that reproduces the numerical feeding rates with good accuracy. The distribution of periapsides of disrupted stars is computed. Time-dependent solutions, f(E,L,t), are also computed, starting from initial conditions similar to those produced by a binary SBH. In these models, feeding rates evolve on two timescales: rapid evolution during which the region evacuated by the massive binary is refilled by angular-momentum diffusion; and slower evolution as diffusion in energy causes the density profile at large radii to attain the Bahcall–Wolf form.

79 ASTRONOMY AND ASTROPHYSICS↗

Correcting for fibre assignment incompleteness in the DESI Bright Galaxy Survey

The Dark Energy Spectroscopic Instrument (DESI) Bright Galaxy Survey (BGS) will be a survey of bright, low-redshift galaxies, which is planned to cover an area of ~14000 square degrees in three passes. Each pass will cover the survey area with ~2000 pointings, each of area ~8 square degrees. The BGS is currently proposed to consist of a bright high priority sample to an r-band magnitude limit r ~ 19.5, with a fainter low priority sample to r ~ 20. The geometry of the DESI fibre positioners in the focal plane of the telescope affects the completeness of the survey and has a non-trivial impact on clustering measurements. Using a BGS mock catalogue, we demonstrate that completeness due to fibre assignment primarily depends on the surface density of galaxies. Completeness is high (>95 per cent) in low-density regions, but very low (<10 per cent) in the centre of massive clusters. We apply the pair inverse probability (PIP) weighting correction to clustering measurements from a BGS mock which has been through the fibre assignment algorithm. This method is only unbiased if it is possible to observe every galaxy pair. To expedite this, we randomly promote a small fraction of the fainter sample to be high priority, and dither the set of tile positions by a small angle. We show that inverse pair weighting combined with angular upweighting provides an unbiased correction to galaxy clustering measurements for the complete three pass survey, and also after one pass, which is highly incomplete.

79 ASTRONOMY AND ASTROPHYSICS↗

Resilience-Oriented DG Siting and Sizing Considering Stochastic Scenario Reduction

In this paper, a fuel-based distributed generator (DG) allocation strategy is proposed to enhance the distribution system resilience against extreme weather. The long-term planning problem is formulated as a two-stage stochastic mixed-integer programming (SMIP). The first stage is to make decisions of DG siting and sizing under the given budget constraint. In the second stage, a post-extreme-event-restoration (PEER) is employed to minimize the operating cost in an uncertain fault scenario. In particular, this study proposes a method to select the most representative scenarios for the SMIP. First, a Monte Carlo Simulation (MCS) is introduced to generate sufficient scenarios considering random fault locations and load profiles. Then, the number of scenarios is reduced by the K-means clustering algorithm. The advantage of scenario reduction is to make a trade-off between accuracy and computational efficiency. Finally, the SMIP is solved by the progressive hedging algorithm. Here, the case studies of the IEEE 33-bus and 123-bus test systems demonstrate the effectiveness of the proposed algorithm in reducing the expected energy not served (EENS), which is a critical criterion of resilience.

42 ENGINEERING↗

SU-E-T-549: A Combinatorial Optimization Approach to Treatment Planning with Non-Uniform Fractions in Intensity Modulated Proton Therapy

Purpose: Non-uniform fractionation, i.e. delivering distinct dose distributions in two subsequent fractions, can potentially improve outcomes by increasing biological dose to the target without increasing dose to healthy tissues. This is possible if both fractions deliver a similar dose to normal tissues (exploit the fractionation effect) but high single fraction doses to subvolumes of the target (hypofractionation). Optimization of such treatment plans can be formulated using biological equivalent dose (BED), but leads to intractable nonconvex optimization problems. We introduce a novel optimization approach to address this challenge. Methods: We first optimize a reference IMPT plan using standard techniques that delivers a homogeneous target dose in both fractions. The method then divides the pencil beams into two sets, which are assigned to either fraction one or fraction two. The total intensity of each pencil beam, and therefore the physical dose, remains unchanged compared to the reference plan. The objectives are to maximize the mean BED in the target and to minimize the mean BED in normal tissues, which is a quadratic function of the pencil beam weights. The optimal reassignment of pencil beams to one of the two fractions is formulated as a binary quadratic optimization problem. A near-optimal solution to this problem can be obtained by convex relaxation and randomized rounding. Results: The method is demonstrated for a large arteriovenous malformation (AVM) case treated in two fractions. The algorithm yields a treatment plan, which delivers a high dose to parts of the AVM in one of the fractions, but similar doses in both fractions to the normal brain tissue adjacent to the AVM. Using the approach, the mean BED in the target was increased by approximately 10% compared to what would have been possible with a uniform reference plan for the same normal tissue mean BED.

61 RADIATION PROTECTION AND DOSIMETRY↗