DOE OSTI2018
Highlights: • We assess the burden of respiratory HAs due to air pollution in Southwest China. • Risks of respiratory HAs were elevated following increased PM{sub 10}, PM{sub 2.5}, NO{sub 2} and SO{sub 2}. • The effect estimates might be modified by age, season and region. • 1.84% of respiratory HAs were attributed to PM{sub 10}, 1.73% to PM{sub 2.5} and 0.34% to SO{sub 2}. Few studies have investigated the respiratory morbidity burden due to ambient air pollution in China, especially in a multi-city setting. This study aimed to estimate the short-term effects of ambient air pollutants (PM{sub 10}, PM{sub 2.5}, NO{sub 2} and SO{sub 2}) on hospital admissions (HAs) for overall and cause-specific respiratory diseases, as well as the associated burden in 17 cities of Sichuan Basin, China during 2015–2016. Firstly, city-specific effect estimates for each pollutant on respiratory HAs were obtained using generalized additive model with quasi-Poisson link, and then random- or fixed-effects meta-analysis was applied to pool the effect estimates at the regional level. Subgroup analyses by sex, age, season and region were also performed. A total of 757,712 respiratory HAs were collected from all the tertiary and secondary hospitals located in the 17 cities. Risks of HAs for overall and cause-specific respiratory diseases were elevated following increased PM{sub 10}, PM{sub 2.5}, NO{sub 2} and SO{sub 2} exposure. An increase of 10 μg/m{sup 3} in PM{sub 10} at lag01, PM{sub 2.5} at lag01, NO{sub 2} at lag0 and SO{sub 2} at lag02 was associated with a 0.43% (95% CI: 0.33%, 0.53%), 0.53% (95% CI: 0.39%, 0.68%), 2.36% (95% CI: 1.75%, 2.98%) and 2.54% (95% CI: 1.51%, 3.59%) increases in total respiratory HAs, respectively. Children (≤ 14 years) and elderly (≥ 65 years) appeared to be more vulnerable to the effects of ambient air pollutants. Comparing to the WHO's air quality guidelines, we estimated that 1.84% (95%CI: 1.42%, 2.25%), 1.73% (95%CI: 1.27%, 2.19%) and 0.34% (95%CI: 0.21%, 0.48%) of respiratory HAs were due to PM{sub 10}, PM{sub 2.5} and SO{sub 2} exposure, respectively. This study suggests that air pollution might be an important trigger of respiratory admissions, and result in substantial burden of HAs for respiratory diseases in Sichuan Basin.
54 ENVIRONMENTAL SCIENCES↗