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At least 73 records · Page 4

A research program to measure the lifetime of spin polarized fuel

The use of spin polarized fuel could increase the deuterium-tritium (D-T) fusion cross section by a factor of 1.5 and, owing to alpha heating, increase the fusion power by an even larger factor. Issues associated with the use of polarized fuel in a reactor are identified. Theoretically, nuclei remain polarized in a hot fusion plasma. The similarity between the Lorentz force law and the Bloch equations suggests polarization can be preserved despite the rich electromagnetic spectrum present in a magnetic fusion device. The most important depolarization mechanisms can be tested in existing devices. The use of polarized deuterium and 3 He in an experiment avoids the complexities of handling tritium, while encompassing the same nuclear reaction spin-physics, making it a useful proxy to study issues associated with full D-T implementation. 3 He fuel with 65% polarization can be prepared by permeating optically-pumped 3 He into a shell pellet. Dynamically polarized 7 Li-D pellets can achieve 70% vector polarization for the deuterium. Cryogenically-frozen pellets can be injected into fusion facilities by special injectors that minimize depolarizing field gradients. Alternatively, polarized nuclei could be injected as a neutral beam. Once injected, the lifetime of the polarized fuel is monitored through measurements of escaping charged fusion products. Multiple experimental scenarios to measure the polarization lifetime in the DIII-D tokamak and other magnetic-confinement facilities are discussed, followed by outstanding issues that warrant further study.

70 PLASMA PHYSICS AND FUSION TECHNOLOGY↗

Effects of radiation environment on reusable nuclear shuttle system

Parametric tradeoff analyses of a wide spectrum of alternate tank configurations to minimize both primary and secondary, direct and scattered radiation sources emanating from the NERVA are reported. The analytical approach utilizing point kernel techniques is described and detailed data are presented on the magnitude of neutron/gamma doses for different locations. Single-tank configurations utilizing smaller cone angles and end cap radii were found to minimize integral radiation levels, hence, stage shielding-weight penalties for shuttle missions. Hybrid configurations employing an upper tank with a reduced cone angle and end cap radius result in low integral payload doses primarily due to the increased separation distance caused by the elongation of the larger capacity upper tank. A preliminary radiation damage assessment is discussed of possible reusable nuclear shuttle materials, components, and subsystems, and the possible effects of the radiation environment on various phases of RNS mission operations.

Lane, A. G.↗

Current NASA In-Situ Resource Utilization (ISRU) Strategic Vision

Perform development to TRL 5/6 through ground demonstration in relevant environment. Perform component/subscale subsystem flight demonstrations on small/mid-size landers. Assess and characterize water in volatiles in lunar polar shadowed regions and craters. Reduce risk of ISRU for mission critical consumables through Integrated End-to-End Flight Demonstrations (pilot scale). Establish initial Human Mission Scale production capability to promote sustainable operations and as anchor for commercial involvement. Identify and characterize polar region environment and resources/volatiles for Science and future Exploration/Commercial applications. Provide ground-truth physical, mineral, and water/volatile resource characteristic information at multiple locations to provide geological context for science-focused theories of volatile placement and initial mining assessments.Test technologies and processes to reduce risk of future extraction/mining systems. Quantify concentration and lateral/vertical distribution of resources/volatiles. Utilize ISRU capabilities to Extend and Enhance Human Lunar Exploration Missions. Provide oxygen (and fuel) to enable reusable human lunar lander (10+ MT/yr O2)Process carbon-based crew waste/trash into gases and propellants; can reduce logistics while minimizing public perception issues (alternative is conversion to radiation shielding). Scavenge unused propellants and hardware from spent landers. Metal extraction from regolith as feedstock for in situ and in space manufacturing demonstrations. Civil engineering and construction aimed at future outpost/infrastructure build-up. Develop and Demonstrate ISRU for Human Mars Missions. ISRU for propellant production (10-15 MT/yr); Liquefy, store, transfer, and refuel ascent vehicle. Use Moon for operational experience and mission validation for Mars: Pre-deployment & remote activation and operation without crew. Storing and transferring mission consumables Landing crew with empty tanks with ISRU propellants already made and waiting. Support/Promote Commercialization of Space. Large scale polar ice mining (100+ MT/yr water)O2/H2 propulsion for landers/cis-lunar transportation with surface and in space depots. In situ construction and energy expansion at mining and human outpost site(s). ISRU Ground Development. Develop and advance ISRU technologies to enable acquisition of resources and processing into mission consumables. Utilize Multi-center collaboration with a portfolio that includes internal NASA work, external contracts, and collaborative agreements/partnerships. Where appropriate, develop lunar ISRU components and subsystems with a Mars-forward application. Engage industry through public-private partnerships to lay the foundation for long-term lunar and space economic development. Spin-in/spin-out technologies for terrestrial applications and industry (mining, oil & gas, alternative energy, construction). Flight Demonstration Path to Operational ISRU. Utilize small demonstrations with near off-the-shelf hardware to obtain critical information quickly on lunar resources and operations. Demonstrate critical technologies and processes that interact with lunar materials and environments. Perform 'pilot plant' demonstrations at architecture relevant scales and durations to reduce the risk for ISRU-provided products for critical human mission applications.

In-situ Resource Utilization↗

Evolving bipartite authentication graph partitions

As large scale enterprise computer networks become more ubiquitous, finding the appropriate balance between user convenience and user access control is an increasingly challenging proposition. Suboptimal partitioning of users’ access and available services contributes to the vulnerability of enterprise networks. Previous edge-cut partitioning methods unduly restrict users’ access to network resources. This paper introduces a novel method of network partitioning superior to the current state-of-the-art which minimizes user impact by providing alternate avenues for access that reduce vulnerability. Networks are modeled as bipartite authentication access graphs and a multi-objective evolutionary algorithm is used to simultaneously minimize the size of large connected components while minimizing overall restrictions on network users. Lastly, results are presented on a real world data set that demonstrate the effectiveness of the introduced method compared to previous naive methods.

97 MATHEMATICS AND COMPUTING↗

Scaling Impacts in Life Support Architecture and Technology Selection

For long-duration space missions outside of Earth orbit, reliability considerations will drive higher levels of redundancy and/or on-board spares for life support equipment. Component scaling will be a critical element in minimizing overall launch mass while maintaining an acceptable level of system reliability. Building on an earlier reliability study (AIAA 2012-3491), this paper considers the impact of alternative scaling approaches, including the design of technology assemblies and their individual components to maximum, nominal, survival, or other fractional requirements. The optimal level of life support system closure is evaluated for deep-space missions of varying duration using equivalent system mass (ESM) as the comparative basis. Reliability impacts are included in ESM by estimating the number of component spares required to meet a target system reliability. Common cause failures are included in the analysis. ISS and ISS-derived life support technologies are considered along with selected alternatives. This study focusses on minimizing launch mass, which may be enabling for deep-space missions.

Lange, Kevin↗

Structure redesign for improved dynamic response

The concepts of multivariable control design are used to redesign structures represented by lumped parameter models. When the mass is held constant, the changing of passive structural members is mathematically equivalent to an output feedback decentralized control problem. When the mass is also allowed to change, a generalization of the output feedback formulation is required. The design objective is to minimize the changes in the structure required to simultaneously satisfy inequality constraints on both the root-mean-square and absolute value of the dynamic response of each output. An alternative objective treated is to minimize the root-mean-square of the dynamic response subject to inequality constraints on the changes allowed in each structural member. Examples illustrate both procedures.

Skelton, R. E.↗

Design Concept for a Minimal Volume Spacecraft Cabin to Serve as a Mars Ascent Vehicle Cabin and Other Alternative Pressurized Vehicle Cabins

The Evolvable Mars Campaign is developing concepts for human missions to the surface of Mars. These missions are round-trip expeditions, thereby requiring crew launch via a Mars Ascent Vehicle (MAV). A study to identify the smallest possible pressurized cabin for this mission has developed a conceptual vehicle referred to as the minimal MAV cabin. The origin of this concept will be discussed as well as its initial concept definition. This will lead to a description of possible configurations to integrate the minimal MAV cabin with ascent vehicle engines and propellant tanks. Limitations of this concept will be discussed, in particular those that argue against the use of the minimal MAV cabin to perform the MAV mission. However, several potential alternative uses for the cabin are identified. Finally, recommended forward work will be discussed, including current work in progress to develop a full scale mockup and conduct usability evaluations.

Howard, Robert L., Jr.↗

Remote Observing with the Keck Telescope Using the ACTS Satellite

As a technical demonstration project for the NASA Advanced Communications Technology Satellite (ACTS), we have implemented remote observing on the 10-meter Keck II telescope on Mauna Kea in Hawaii from the California Institute of Technology campus in Pasadena. The data connection consists of optical fiber networks in Hawaii and California, connecting the end-points to high data rate (HDR) ACTS satellite antennae at JPL in Pasadena and at the Tripler Army Medical Center in Honolulu. The terrestrial fiber networks run the asynchronous transfer mode (ATM) protocol at DS-3 (45 Mbit/sec) speeds, providing ample bandwidth to enable remote observing with a software environment identical to that used for on-site observing in Hawaii. This experiment has explored the data requirements of remote observing with a modern research telescope and large-format detector arrays. While the maximum burst data rates are lower than those required for many other applications (e.g., HDTV), the network reliability and data integrity requirements are critical. As we show in this report, the former issue particularly may be the greatest challenge for satellite networks for this class of application. We have also experimented with the portability of standard TCP/IP applications to satellite networks, demonstrating the need for alternative TCP congestion algorithms and minimization of bit error rates (BER). Reliability issues aside, we have demonstrated that true remote observing over high-speed networks provides several important advantages over standard observing paradigms. Technical advantages of the high-speed network access include more rapid download of data to a user's home institution and the opportunity for alternative communication facilities between members of an observing team, such as audio- and videoconferencing.

SATELLITE COMMUNICATIONS↗

Two-Level Sketching Alternating Anderson Acceleration for Complex Physics Applications

We present a novel two-level sketching extension of the Alternating Anderson–Picard (AAP) method for accelerating fixed-point iterations in challenging single- and multiphysics simulations governed by discretized PDEs. Our approach combines a static, physics-based projection that reduces the least-squares (LS) problem to the most informative field (e.g., via Schur-complement insight) with a dynamic, algebraic sketching stage driven by a backward stability analysis under Lipschitz continuity. We introduce inexpensive estimators for stability thresholds and cache-aware randomized selection strategies to balance computational cost against memory access overhead. The resulting algorithm solves reduced LS systems in place, minimizes memory footprints, and seamlessly alternates between low-cost Picard updates and Anderson mixing. Implemented in Julia, our two-level sketching AAP achieves up to 50% time-to-solution reductions compared to standard Anderson acceleration—without degrading convergence rates—on benchmark problems including Stokes, 𝑝-Laplacian, bidomain, and Navier–Stokes formulations at varying problem sizes. These results demonstrate the method’s robustness, scalability, and potential for integration into high-performance scientific computing frameworks. Our implementation is available open source in the AAP.jl library.

Barnafi, Nicolas [University of Chile, Santiago]↗

Using Digital Waveforms to Mitigate Solvent Clustering During Mass Filter Analysis of Proteins

With advances in the precision of digital electronics, waveform generation technology has progressed to a state that enables the creation of m/z filters that are purely digitally driven. These advances present new methods of performing mass analyses that provide information from a chemical system that are inherently difficult to achieve by other means. One notable characteristic of digitally driven mass filters is the capacity to transmit ions at m/z ratios that vastly exceed the capabilities of traditional resonant systems. However, the capacity to probe ion m/z ratios that span multiple orders of magnitudes across multiple orders of magnitude presents a new set of issues requiring a solution. In the present work, when probing multiply charged protein species beyond m/z 2000 using a gentle atmospheric pressure interface, the presence of solvent adducts and poorly resolved multimers can severely degrade spectral fidelity. Increasing energy imparted into a target ion population is one approach minimizing these clusters; however, the use of digital waveform technology provides an alternative that maximizes ion transport efficiency and simultaneously minimizes solvent clustering. In addition to the frequency of the applied waveform, digital manipulation also provides control over the duty cycle of the target waveform. This work examines the conditions and approach leading to optimal digital waveform operation to minimize solvent clustering. .

46 INSTRUMENTATION RELATED TO NUCLEAR SCIENCE AND ↗

Proposed minimal standards for description of methanogenic archaea

Methanogenic archaea are a diverse, polyphyletic group of strictly anaerobic prokaryotes capable of producing methane as their primary metabolic product. It has been over three decades since minimal standards for their taxonomic description have been proposed. In light of advancements in technology and amendments in systematic microbiology, revision of the older criteria for taxonomic description is essential. Most of the previously recommended minimum standards regarding phenotypic characterization of pure cultures are maintained. Electron microscopy and chemotaxonomic methods like whole-cell protein and lipid analysis are desirable but not required. Because of advancements in DNA sequencing technologies, obtaining a complete or draft whole genome sequence for type strains and its deposition in a public database are now mandatory. Genomic data should be used for rigorous comparison to close relatives using overall genome related indices such as average nucleotide identity and digital DNA–DNA hybridization. Phylogenetic analysis of the 16S rRNA gene is also required and can be supplemented by phylogenies of the mcrA gene and phylogenomic analysis using multiple conserved, single-copy marker genes. Additionally, it is now established that culture purity is not essential for studying prokaryotes, and description of Candidatus methanogenic taxa using single-cell or metagenomics along with other appropriate criteria is a viable alternative. The revisions to the minimal criteria proposed here by the members of the Subcommittee on the Taxonomy of Methanogenic Archaea of the International Committee on Systematics of Prokaryotes should allow for rigorous yet practical taxonomic description of these important and diverse microbes.

Microbiology↗

Adaptive, Distributed Control of Constrained Multi-Agent Systems

Product Distribution (PO) theory was recently developed as a broad framework for analyzing and optimizing distributed systems. Here we demonstrate its use for adaptive distributed control of Multi-Agent Systems (MASS), i.e., for distributed stochastic optimization using MAS s. First we review one motivation of PD theory, as the information-theoretic extension of conventional full-rationality game theory to the case of bounded rational agents. In this extension the equilibrium of the game is the optimizer of a Lagrangian of the (Probability dist&&on on the joint state of the agents. When the game in question is a team game with constraints, that equilibrium optimizes the expected value of the team game utility, subject to those constraints. One common way to find that equilibrium is to have each agent run a Reinforcement Learning (E) algorithm. PD theory reveals this to be a particular type of search algorithm for minimizing the Lagrangian. Typically that algorithm i s quite inefficient. A more principled alternative is to use a variant of Newton's method to minimize the Lagrangian. Here we compare this alternative to RL-based search in three sets of computer experiments. These are the N Queen s problem and bin-packing problem from the optimization literature, and the Bar problem from the distributed RL literature. Our results confirm that the PD-theory-based approach outperforms the RL-based scheme in all three domains.

Bieniawski, Stefan↗

Percutaneous Isolated Hepatic Perfusion for the Treatment of Unresectable Liver Malignancies

Liver malignancies are a major burden of disease worldwide. The long-term prognosis for patients with unresectable tumors remains poor, despite advances in systemic chemotherapy, targeted agents, and minimally invasive therapies such as ablation, chemoembolization, and radioembolization. Thus, the demand for new and better treatments for malignant liver tumors remains high. Surgical isolated hepatic perfusion (IHP) has been shown to be effective in patients with various hepatic malignancies, but is complex, associated with high complication rates and not repeatable. Percutaneous isolated liver perfusion (PHP) is a novel minimally invasive, repeatable, and safer alternative to IHP. PHP is rapidly gaining interest and the number of procedures performed in Europe now exceeds 200. This review discusses the indications, technique and patient management of PHP and provides an overview of the available data.

62 RADIOLOGY AND NUCLEAR MEDICINE↗

Luteibacter mycovicinus sp. nov., a yellow-pigmented gammaproteobacterium found as an endohyphal symbiont of endophytic Ascomycota

We isolated and described a yellow-pigmented strain of bacteria (strain 9143 T ), originally characterized as an endohyphal inhabitant of an endophytic fungus in the Ascomycota. Although the full-length sequence of its 16S rRNA gene displays 99 % similarity to Luteibacter pinisoli, genomic hybridization demonstrated <30 % genomic similarity between 9143 T and its closest named relatives, further supported by average nucleotide identity results. This and related endohyphal strains form a well-supported clade separate from L. pinisoli and other validly named species including the most closely related Luteibacter rhizovicinus. The name Luteibacter mycovicinus sp. nov. is proposed, with type strain 9143 T (isolate DBL433), for which a genome has been sequenced and is publicly available from the American Type Culture Collection (ATCC TSD-257 T ) and from the Leibniz Institute DSMZ (DSM 112764 T ). The type strain reliably forms yellow colonies across diverse media and growth conditions (lysogeny broth agar, King’s Medium B, potato dextrose agar, trypticase soy agar and Reasoner's 2A (R2A) agar). It forms colonies readily at 27 °C on agar with a pH of 6–8, and on salt (NaCl) concentrations up to 2 %. It lacks the ability to utilize sulphate as a sulphur source and thus only forms colonies on minimal media if supplemented with alternative sulphur sources. It is catalase-positive and oxidase-negative. Although it exhibits a single polar flagellum, motility was only clearly visible on R2A agar. Its host range and close relatives, which share the endohyphal lifestyle, are discussed.

59 BASIC BIOLOGICAL SCIENCES↗

SU-F-T-647: Linac-Based Stereotactic Radiosurgery (SRS) in the Treatment of Trigeminal Neuralgia: Detailed Description of SRS Procedural Technique and Reported Clinical Outcomes

Purpose: SRS is an effective non-invasive alternative treatment modality with minimal-toxicity used to treat patients with medically/surgically refractory trigeminal neuralgia root(TNR) or those who may not tolerate surgical intervention. We present our linac-based SRS procedure for TNR treatment and simultaneously report our clinical outcomes. Methods: Twenty-eight TNR-patients treated with frame-based SRS at our institution (2009–2015) with a single-fraction point-dose of 60-80Gy to TNR were included in this IRB-approved study. Experienced neurosurgeon and radiation oncologist delineated the TNR on 1.0mm thin 3D-FIESTA-MRI that was co-registered with 0.7mm thin planning-CT. Treatment plans were generated in iPlan (BrainLAB) with a 4-mm diameter cone using 79 arcs with differential-weighting for Novalis-TX 6MV-SRS(1000MU/min) beam and optimized to minimize brainstem dose. Winston-Lutz test was performed before each treatment delivery with sub-millimeter isocenter accuracy. Quality assurance of frame placement was maintained by helmet-bobble-measurement before simulation-CT and before patient setup at treatment couch. OBI-CBCT scan was performed for patient setup verification without applying shifts. On clinical follow up, treatment response was assessed using Barrow Neurological Institute Pain Intensity Score(BNI-score:I–V). Results: 26/28 TNR-patients (16-males/10-females) who were treated with following single-fraction point-dose to isocenter: 80Gy(n=22),75Gy(n=1),70Gy(n=2) and 60Gy(n=1, re-treatment) were followed up. Median follow-up interval was 8.5-months (ranged:1–48.5months). Median age was 70-yr (ranged:43–93-yr). Right/left TNR ratio was 15/11. Delivered total # of average MUs was 19034±1204. Average beam-on-time: 19.0±1.3min. Brainstem max-dose and dose to 0.5cc were 13.3±2.4Gy (ranged:8.1–16.5Gy) and 3.6±0.4Gy (ranged:3.0–4.9Gy). On average, max-dose to optic-apparatus was ≤1.2Gy. Mean value of max-dose to eyes/lens was 0.26Gy/0.11Gy. Overall, 20-patients (77%) responded to treatment: 5(19%) achieved complete pain relief without medication (BNI score: I); 5(19%) had no-pain, decreased medication (BNI-score:II); 2(7.7%) had no-pain, but, continued medication (BNI-score:IIIA), and 8(30.8%) had pain that was well controlled by medication (BNI-score: IIIB). Six-patients (23.0%) did not respond to treatment (BNI-score:IV–V). Neither cranial nerve deficit nor radio-necrosis of temporal lobe was clinically observed. Conclusion: Linac-based SRS for medically/surgically refractory TNR provided an effective treatment option for pain resolution/control with very minimal if any normal tissue toxicity. Longer follow up of these patients is anticipated/needed to confirm our observations.

60 APPLIED LIFE SCIENCES↗

Facilitated Direct Liquid Fuel Cells with High Temperature Membrane Electrode Assemblies

Dimethyl ether (DME) is a liquid fuel of great potential impact due to its exceptionally high energy density. However, it has received minimal prior investigation as an alternative to either purified hydrogen or other liquid fuels, including methanol (MeOH). In the limited published literature work on direct dimethyl ether fuel cells, regardless of operating temperature, PtRu (either supported or unsupported on carbon) has been established as the standard catalyst of choice. The majority of the work in this program also utilized a Johnson Matthey (JM) HiSPEC ® 12100 PtRu/C (nominally 50% Pt, 25% Ru) while looking at electrode optimizations, beginning of life (BoL) performance, pressure- and temperature-dependent studies to look at the effect of binding affinity of DME oxidation intermediates, mass transport effects, crossover studies, and durability. However, it does also investigate some promising alternatives to PtRu/C as well, which should be investigated in more detail in further work. Those catalysts include a pair of ternary PtRuPd/C catalysts (from Los Alamos National Laboratory (LANL) and Pajarito Powder, LLC. (PP)) as well as a Pt 2 Bi Black catalyst from Professor Anastasios Angelopoulos of the University of Cincinnati (UC). This work achieved several project objectives, including an optimization of the membrane electrode assembly (MEA) process using PtRu/C anode catalyst. Additionally, these direct dimethyl ether fuel cells (DDFCs) were able to match or exceed many performance metrics for the state-of-the-art (SOA) direct methanol fuel cells (DMFCs), a primary and more evolved competitor to direct dimethyl ether fuel cells. This included peak specific power, total platinum group metal (PGM) loading, crossover current, degradation rate, start/stop cycling losses, and anode specific current.

09 BIOMASS FUELS↗

The calculation of supersonic viscous flows using the parabolized Navier-Stokes equations

Solution of the parabolic Navier-Stokes (PNS) equations for supersonic flows is discussed, and compatibility of the PNS method with the triple-deck theory of Stewartson (1974) is demonstrated. Characteristic and stability analyses show that use of an appropriate filter on the pressure term in the x-momentum equation can suppress the departure solutions, giving the usual desired weak interaction solution. An Alternating Direction Explicit procedure, with minimal computer storage requirements compared to the full Navier-Stokes solvers, is proposed to calculate strongly interacting flows using a global iteration procedure for the PNS equations. The PNS equations are used to solve the hypersonic viscous interaction problem, and good agreement is found with experimental results.

Davis, R. T.↗

Implementation of Vigneron's streamwise pressure gradient approximation in the PNS equations

For single sweep parabolized Navier-Stokes solvers, the streamwise pressure gradient must be modified in the subsonic region to eliminate numerical instabilities. The accuracy of this modification on the solution of the parabolized Navier-Stokes equations with Vigneron's technique is shown to depend on how the numerical approximation of the pressure gradient is formed. A simple test case of supersonic laminar flow over a flat plate is computed with two different numerical methods for solving the PNS equations. Significant errors in the temperature profile and skin friction coefficient are demonstrated using a fully conservative differencing treatment of Vigneron's splitting for the pressure gradient typically used in parabolized Navier-Stokes solvers. The physical reason for this error is discussed. An alternate formulation is demonstrated which minimizes these errors.

Morrison, Joseph H.↗