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At least 703 records · Page 39

Path-BigBird: An AI-Driven Transformer Approach to Classification of Cancer Pathology Reports

PURPOSE Surgical pathology reports are critical for cancer diagnosis and management. To accurately extract information about tumor characteristics from pathology reports in near real time, we explore the impact of using domain-specific transformer models that understand cancer pathology reports. METHODS We built a pathology transformer model, Path-BigBird, by using 2.7 million pathology reports from six SEER cancer registries. We then compare different variations of Path-BigBird with two less computationally intensive methods: Hierarchical Self-Attention Network (HiSAN) classification model and an offthe-shelf clinical transformer model (Clinical BigBird). We use five pathology information extraction tasks for evaluation: site, subsite, laterality, histology, and behavior. Model performance is evaluated by using macro and micro F 1 scores. RESULTS We found that Path-BigBird and Clinical BigBird outperformed the HiSAN in all tasks. Clinical BigBird performed better on the site and laterality tasks. Versions of the Path-BigBird model performed best on the two most difficult tasks: subsite (micro F 1 score of 72.53, macro F 1 score of 35.76) and histology (micro F 1 score of 80.96, macro F 1 score of 37.94). The largest performance gains over the HiSAN model were for histology, for which a Path-BigBird model increased the micro F 1 score by 1.44 points and the macro F 1 score by 3.55 points. Overall, the results suggest that a Path-BigBird model with a vocabulary derived from wellcurated and deidentified data is the best-performing model. CONCLUSION The Path-BigBird pathology transformer model improves automated information extraction from pathology reports. Although Path-BigBird outperforms Clinical BigBird and HiSAN, these less computationally expensive models still have utility when resources are constrained.

60 APPLIED LIFE SCIENCES↗

Natural Language Processing-Enhanced Nuclear Industry Operating Experience Data Analysis: Aggregation and Interpretation of Multi-Report Analysis Results

Industry-wide operating experience is a critical source of raw data for reliability and risk model parameter estimations for nuclear power plants. A large portion of operating experience data are failure events stored as reports that contain unstructured data, such as narratives. In current practice, a failure report is usually reviewed and manually coded by analysts. The coding is based on extracting several event characteristics such as system name, component type, sub-part type, failure mode, and failure cause. Event narratives are mostly used to help understand events and extract their characteristics. In this line of research, we aim to maximize the usage of event narratives by leveraging natural language processing (NLP) methods to automatically convert an event narrative to a causal graph. This research has promise to improve physical understanding of failure initiation and propagation and to facilitate use of non-failure data (e.g., near-misses and degradations) to complement the limited data pool of failures. In our previous work, we developed an NLP tool and applied it to analyze a number of licensee event reports submitted by U.S. nuclear power plants to the Nuclear Regulatory Commission. In this paper, we will report our recent research progress in aggregating the results of multiple reports, developing network model(s), and drawing statistical insights.

99 GENERAL AND MISCELLANEOUS↗

ESS-DIVE Reporting Format for Location Metadata

The ESS-DIVE location metadata reporting format provides instructions and templates for reporting a minimum set of metadata for discrete point locations in geographic space represented by x, y, and z coordinates. This format was created based on a need for earth and environmental science researchers to more consistently provide metadata about locations where they conduct studies. To create the format, we incorporated elements from ESS-DIVE’s community reporting formats as well as 12 additional data standards or other data resources (e.g., databases, data systems, or repositories). In the template, we ask researchers to indicate unique locations using Location IDs and indicate hierarchies of locations through parent location IDs. We also provide additional optional fields for researchers to indicate how they measured the point location and the date and time that the location was first used as a research siteThis dataset contains support documentation for the reporting format (README.md and instructions.md), a terminology guide (guide.md), a crosswalk indicating how this reporting format relates to existing standards and data resources (Location_metadata_crosswalk.csv), a data dictionary (dd.csv), file-level metadata (flmd.csv), and the location metadata templates in both CSV (Location_metadata_template.csv) and Excel formats (Location_metadata_template.xlsx).

54 ENVIRONMENTAL SCIENCES↗

U.S. Offshore Pipeline and Reported Incident Datasets

The U.S. Offshore Pipeline and Reported Incident Datasets provide a compilation of data from a variety of credible resources, spatially-temporally integrated into multivariate resources. This spatial resource includes more than 80,000 points along existing and abandoned pipelines in the Gulf with matched incidents based on similar lease blocks and temporal timelines (e.g., the incident date occurs within reported pipeline lifespan), structural characteristics, geologic and seafloor data, and meteorological, oceanographic, and biochemical statistics spatially and temporally matched to each point. This is provided as both a feature class in a file geodatabase, as well as a CSV file for ease of use. The pipeline incidents table is a CSV file containing more than 900 reported incidents from 1986 to 2021, including incident date, area (Outer Continental Shelf (OCS) lease block and area code), reported causes, reported incident information, and results (i.e., cost, repairs, inspections), along with quantitative severity metrics. Field dictionaries are included for both the pipeline locations and incidents datasets, which detail field definitions. The pipeline locations field dictionary includes original resource reference information.

Advanced Infrastructure Integrity Model↗

Extracting and Applying SV-SV Shear Modes from Vertical Vibrator Data Across Geothermal Prospects Final Report

This 3-year project was terminated at the end of Year 1 because the DOE Geothermal project-evaluation committee decided one Milestone was not met and also concluded that our technology would not be successful. The Review Panel recommended a? no-go? decision be implemented by DOE. The Principal Investigator and his research team disagreed with the conclusions reached by the DOE evaluation committee and wrote a scientifically based rebuttal to the erroneous claims made by the evaluators. We were not told if our arguments were presented to the people who evaluated our work and made the? no-go? decision. Whatever the case regarding the information we supplied in rebuttal, we received an official letter from Laura Merrick, Contracting Officer at the Golden Field Office, dated June 11, 2013 in which we were informed that project funding would cease and instructed us to prepare a final report before September 5, 2013. In spite of the rebuttal arguments we presented to DOE, this official letter repeated the conclusions of the Review Panel that we had already proven to be incorrect. This is the final report that we are expected to deliver. The theme of this report will be another rebuttal of the technical deficiencies claimed by the DOE Geothermal Review Panel about the value and accomplishments of the work we did in Phase 1 of the project. The material in this report will present images made from direct-S modes produced by vertical-force sources using the software and research findings we developed in Phase 1 that the DOE Review Panel said would not be successful. We made these images in great haste when we were informed that DOE Geothermal rejected our rebuttal arguments and still regarded our technical work to be substandard. We thought it was more important to respond quickly rather than to take additional time to create better quality images than what we present in this Final Report.

15 GEOTHERMAL ENERGY↗

International Linear Collider Technical Design Report - Volume 2: Physics

For more than twenty years, an advanced electron-positron collider has been put forward as a key component of the future program of elementary particle physics. We have a well-established Standard Model of particle physics, but it is known to be incomplete. Among the many questions that this model leaves open, there are two — the origin of the masses of elementary particles and the particle identity of cosmic dark matter – that should be addressed at energy scales below 1 TeV. It has been appreciated for a long time that a next-generation electron-positron collider would give us the ability to make precision measurements that would shed light on these mysteries. Now the technology to build this electron-positron collider has come of age. This report is a volume of the Technical Design Report for the International Linear Collider (ILC). The accompanying volumes of this report lay out the technical design of a high-luminosity e + e - collider at 500 GeV in the center of mass and of detectors that could make use of the collisions to perform high-precision measurements. In this volume, we summarize the physics arguments for building this collider and their appropriate relation to the situation of particle physics as of the fall of 2012. The discussion in this volume supplements the presentation of the physics opportunities for a 500 GeV e + e - collider given in the review articles, the 2001 regional study reports, the 2006 study of ILC/LHC complementarity, and the 2007 ILC Reference Design Report.

43 PARTICLE ACCELERATORS↗

Final Report on C8 Enhanced Surveillance Campaign Milestone L2 4654: Surveillance Metrics Assessments on Selected Weapons

In December 2012, LANL Enhanced Surveillance was tasked with milestone L2 4654 to provide an assessment of the results of the Surveillance Metrics Team approaches to metrics. The goal was to provide an assessment and comparison of the two approaches. The approaches are labeled Approach 1 and Approach 2 based on their order of development. Approach 1 was developed by LLNL (initially December 2009) to be a high level, non data-intensive snapshot for the stockpile health for each system. Approach 2 was a statistically-based approach developed by SNL and LANL over a period from 2009-2012 as a means to analyze Core Surveillance data and answer the question of whether there is an adequate amount of Core Surveillance data. The two approaches are summarized below along with key differences. Both approaches were developed to respond to an August 10, 2009 Dr. Greenaugh memo which requested, “metric(s) describing the results of realized and, non-realized surveillance activities on our confidence in reporting reliability and assessing the stockpile”. Both approaches were developed to satisfy the developers’ interpretation of the memo and be useful for their work. Both approaches are being used by their respective developers and so the memo has caused positive change in surveillance. This report looks at what is reported, possible problems, and some opportunities that exist. This report expands the conventional idea of “non-realized” surveillance activities to include “opportunities” that could allow surveillance activities to improve the confidence in reporting reliabilities. These “non-realized surveillance” opportunities are important to consider along with the current surveillance activities.

45 MILITARY TECHNOLOGY, WEAPONRY, AND NATIONAL DEF↗

ILAW PCT, VHT, Viscosity, and Electrical Conductivity Model Development (Final Report)

This report describes the results of work and testing specified by the Test Specifications (24590-LAW-TSP-RT-01-013 Rev.1 and 24590-WTP-TSP-RT-02-001 Rev.0), Test Plans (VSL-02T4800-1 Rev.1 & TP-RPP-WTP-179 Rev.1), and Text Exception (24590-WTP-TEF-RT-03-040). The work and any associated testing followed established quality assurance requirements and conducted as authorized. The descriptions provided in this test report are an accurate account of both the conduct of the work and the data collected. Results required by the Test Plans are reported. Also reported are any unusual or anomalous occurrences that are different from the starting hypotheses. The test results and this report have been reviewed and verified.

12 MANAGEMENT OF RADIOACTIVE AND NON-RADIOACTIVE W↗

Reported Energy and Cost Savings from the DOE ESPC Program: FY 2013

The objective of this work was to determine the realization rate of energy and cost savings from the Department of Energy’s Energy Savings Performance Contract (ESPC) program based on information reported by the energy services companies (ESCOs) that are carrying out ESPC projects at federal sites. Information was extracted from 152 Measurement and Verification (M&V) reports to determine reported, estimated, and guaranteed cost savings and reported and estimated energy savings for the previous contract year. Because the quality of the reports varied, it was not possible to determine all of these parameters for each project.

29 ENERGY PLANNING, POLICY, AND ECONOMY↗

Technology Deployment Annual Report 2013 December

Idaho National Laboratory (INL) is a Department of Energy (DOE) multi-program national laboratory that conducts research and development in all DOE mission areas. Like all other federal laboratories, INL has a statutory technology transfer mission to make its capabilities and technologies available to all federal agencies, to state and local governments, and to universities and industry. To fulfill this mission, INL encourages its scientific, engineering, and technical staff to disclose new inventions and creations to ensure the resulting intellectual property is captured, protected, and made available to others who might benefit from it. As part of the mission, intellectual property is licensed to industrial partners for commercialization, creating jobs and delivering the benefits of federally funded technology to consumers. In other cases, unique capabilities are made available to other federal agencies or to regional small businesses to solve specific technical challenges. INL employees also work cooperatively with researchers and technical staff from the university and industrial sectors to further develop emerging technologies. In a multinational global economy, INL is contributing to the development of the next generation of engineers and scientists by licensing software to educational institutions throughout the world. This report is a catalog of selected INL technology transfer and commercialization transactions during this past year. The size and diversity of INL technical resources, coupled with the large number of relationships with other organizations, virtually ensures that a report of this nature will fail to capture all interactions. Recognizing this limitation, this report focuses on transactions that are specifically authorized by technology transfer legislation (and corresponding contractual provisions) or involve the transfer of legal rights to technology to other parties. This report was compiled from primary records, which were readily available to the INL’s Office of Technology Deployment. However, the accomplishments cataloged in the report reflect the achievements and creativity of the researchers, technicians, support staff, and operators of the INL workforce.

99 GENERAL AND MISCELLANEOUS↗

AGR-3/4 Data Qualification Report for ATR Cycles 151A, 151B, 152A, 152B, 154A, and 154B

This data report provides the qualification status of Advanced Gas Reactor-3/4 (AGR-3/4) fuel irradiation experimental data from Advanced Test Reactor (ATR) Cycles 151A, 151B, 152A, 152B, 154A, and 154B, as recorded in the Nuclear Data Management and Analysis System (NDMAS). Of these cycles, ATR Cycle 152A is a low power cycle that occurred when the ATR core was briefly at low power. The irradiation data are not used for physics and thermal calculation, but the qualification status of these cycle data is still covered in this report. On the other hand, during ATR Cycles 153A (unplanned Outage cycle) and 153B (Power Axial Locator Mechanism [PALM] cycle), the AGR-3/4 was pulled out from the ATR core and stored in the canal to avoid being overheated. Therefore, qualification of the AGR-3/4 irradiation data from these 2 cycles was excluded in this report. By the end of ATR Cycle 154B, AGR-3/4 was irradiated for a total of 264.1 effective full power days. The AGR-3/4 data streams addressed in this report include thermocouple (TC) temperatures, sweep gas data (flow rates, pressure, and moisture content), and Fission Product Monitoring System (FPMS) data (release rates and release-to-birth rate ratios [R/Bs]) for each of the twelve capsules in the AGR-3/4 experiment. The final data qualification status for these data streams is determined by a Data Review Committee (DRC) composed of AGR technical leads, Sitewide Quality Assurance (QA), and NDMAS analysts. The DRC convened on February 12, 2014, reviewed the data acquisition process, and considered whether the data met the requirements for data collection as specified in QA-approved Very High Temperature Reactor (VHTR) Technology Development Office (TDO) data collection plans. The DRC also examined the results of NDMAS data testing and statistical analyses, and confirmed the qualification status of the data as given in this report.

11 NUCLEAR FUEL CYCLE AND FUEL MATERIALS↗

The Oncor Geodatabase for the Columbia Estuary Ecosystem Restoration Program (Annual Report, 2012)

The study reported herein was conducted by researchers at the Pacific Northwest National Laboratory (PNNL) for the U.S. Army Corps of Engineers, Portland District (Corps). The purpose of the project is to develop a geospatial, web-accessible database (called Oncor) for action effectiveness and related data from monitoring and research efforts for the Columbia Estuary Ecosystem Restoration Program (CEERP). The intent is for the Oncor database to enable synthesis and evaluation, the results of which can then be applied in subsequent CEERP decision-making. This is the first annual report in what is expected to be a 3- to 4-year project, which commenced on February 14, 2012. This report covers project activities conducted from February 2012 through February 2013. The specific objectives and tasks for the 2012 study year were as enumerated here. 1) Coordination - Coordinate with CEERP funding agencies and regional stakeholders to finalize key analysis questions and database needs for research, monitoring, and evaluation (RME) and ecosystem restoration in the lower Columbia River and estuary (LCRE) within CEERP’s adaptive management framework. 2) Database Development - Develop and demonstrate a web-based proof-of-concept geospatial database management system and analysis system for CEERP. 3) Analysis and Synthesis - Draft the CEERP 2012 Strategy Report, 2012 Action Plan, and 2013 Synthesis and Evaluation Memorandum, and provide other analytical and programmatic support. Work products for Objective 3 were reported separately.

Coleman, Andre M.↗

Hanford Apatite Treatability Test Report Errata: Apatite Mass Loading Calculation

The objective of this errata report is to document an error in the apatite loading (i.e., treatment capacity) estimate reported in previous apatite treatability test reports and provide additional calculation details for estimating apatite loading and barrier longevity. The apatite treatability test final report (PNNL-19572; Vermeul et al. 2010) documents the results of the first field-scale evaluation of the injectable apatite PRB technology. The apatite loading value in units of milligram-apatite per gram-sediment is incorrect in this and some other previous reports. The apatite loading in units of milligram phosphate per gram-sediment, however, is correct, and this is the unit used for comparison to field core sample measurements.

apatite↗

Hanford Site Waste Management Units Report

The Hanford Site Waste Management Units Report (HSWMUR) has been created to meet the requirements of the Tri-Party Agreement (TPA) Action Plan, Section 3.5, which states: “The Hanford Site Waste Management Units Report shall be generated, in a format agreed upon by the Parties, as a calendar year report and issued annually by the DOE by the end of February of each year, and posted electronically for regulator and public access. This report shall reflect all changes made in waste management unit status during the previous year.” This February 2013 version of the HSWMUR contains a comprehensive inventory of the 3438 sites and 569 subsites in the Waste Information Data System (WIDS). The information for each site contains a description of each unit and the waste it contains, where applicable. The WIDS database provides additional information concerning the sites contained in this report and is maintained with daily changes to these sites.

12 MANAGEMENT OF RADIOACTIVE AND NON-RADIOACTIVE W↗

2013 Los Alamos National Laboratory Hazardous Waste Minimization Report

Waste minimization and pollution prevention are inherent goals within the operating procedures of Los Alamos National Security, LLC (LANS). The US Department of Energy (DOE) and LANS are required to submit an annual hazardous waste minimization report to the New Mexico Environment Department (NMED) in accordance with the Los Alamos National Laboratory (LANL or the Laboratory) Hazardous Waste Facility Permit. The report was prepared pursuant to the requirements of Section 2.9 of the LANL Hazardous Waste Facility Permit. This report describes the hazardous waste minimization program (a component of the overall Waste Minimization/Pollution Prevention [WMin/PP] Program) administered by the Environmental Stewardship Group (ENV-ES). This report also supports the waste minimization and pollution prevention goals of the Environmental Programs Directorate (EP) organizations that are responsible for implementing remediation activities and describes its programs to incorporate waste reduction practices into remediation activities and procedures. LANS was very successful in fiscal year (FY) 2013 (October 1-September 30) in WMin/PP efforts. Staff funded four projects specifically related to reduction of waste with hazardous constituents, and LANS won four national awards for pollution prevention efforts from the National Nuclear Security Administration (NNSA). In FY13, there was no hazardous, mixedtransuranic (MTRU), or mixed low-level (MLLW) remediation waste generated at the Laboratory. More hazardous waste, MTRU waste, and MLLW was generated in FY13 than in FY12, and the majority of the increase was related to MTRU processing or lab cleanouts. These accomplishments and analysis of the waste streams are discussed in much more detail within this report.

54 ENVIRONMENTAL SCIENCES↗

Nevada National Security Site Environmental Report 2014

This Nevada Nuclear Security Site Environmental Report (NNSSER) was prepared to satisfy DOE Order DOE O 231.1B, “Environment, Safety and Health Reporting.” Its purpose is to (1) report compliance status with environmental standards and requirements, (2) present results of environmental monitoring of radiological and nonradiological effluents, (3) report estimated radiological doses to the public from releases of radioactive material, (4) summarize environmental incidents of noncompliance and actions taken in response to them, (5) describe the NNSA/NFO Environmental Management System and characterize its performance, and (6) highlight significant environmental programs and efforts.This NNSSER summarizes data and compliance status for calendar year 2014 at the Nevada National Security Site (NNSS) (formerly the Nevada Test Site) and its two support facilities, the North Las Vegas Facility (NLVF) and the Remote Sensing Laboratory–Nellis (RSL-Nellis). It also addresses environmental restoration (ER) projects conducted at the Tonopah Test Range (TTR) and the Nevada Test and Training Range (NTTR). Through a Memorandum of Agreement, NNSA/NFO is responsible for the oversight of these ER projects, and the Sandia Field Office of NNSA (NNSA/SFO) has oversight of all other TTR and NTTR activities. NNSA/SFO produces the TTR annual environmental report, which is available at http://www.sandia.gov/news/publications/environmental/index.html.Major Site Programs and Facilities NNSA/NFO directs the management and operation of the NNSS and six sites across the nation. The six sites include two in Nevada (NLVF and RSL-Nellis) and four in other states (RSL-Andrews in Maryland, Livermore Operations in California, Los Alamos Operations in New Mexico, and Special Technologies Laboratory in California). Los Alamos, Lawrence Livermore, and Sandia National Laboratories are the principal organizations that sponsor and implement the nuclear weapons programs at the NNSS. National Security Technologies, LLC (NSTec), is the current Management and Operating contractor accountable for the successful execution of work and ensuring that work is performed in compliance with environmental regulations. The six sites all provide support to enhance the NNSS as a location for weapons experimentation and nuclear test readiness. The three major NNSS missions include National Security/Defense, Environmental Management, and Nondefense. The major programs that support these missions are Stockpile Stewardship and Management, Nonproliferation and Counterterrorism, Nuclear Emergency Response, Strategic Partnership Projects, Environmental Restoration, Waste Management, Conservation and Renewable Energy, Other Research and Development, and Infrastructure. The major facilities that support the programs include the U1a Facility, Big Explosives Experimental Facility (BEEF), Device Assembly Facility, Dense Plasma Focus Facility, Joint Actinide Shock Physics Experimental Research Facility, Radiological/Nuclear Countermeasures Test and Evaluation Complex, Nonproliferation Test and Evaluation Complex (NPTEC), Radiological/Nuclear Weapons of Mass Destruction Incident Exercise Site (known as the T-1 Site), Area 5 Radioactive Waste Management Complex (RWMC), and the Area 3 Radioactive Waste Management Site (RWMS).

54 ENVIRONMENTAL SCIENCES↗

Technology Transfer Annual Report Fiscal Year 2015

Idaho National Laboratory (INL) is a Department of Energy (DOE) multi-program national laboratory that conducts research and development in all DOE mission areas. Like all other federal laboratories, INL has a statutory, technology transfer mission to make its capabilities and technologies available to federal agencies, state and local governments, universities, and industry. To fulfill this mission, INL encourages its scientific, engineering, and technical staff to disclose new inventions and creations to ensure the resulting intellectual property is captured, protected, and available to others who might benefit from it. As part of the mission, intellectual property is licensed to industrial partners for commercialization, job creation, and delivering the benefits of federally funded technology to consumers. In some cases, unique capabilities are made available to other federal agencies, international organizations, domestic and foreign commercial entities, or small businesses to solve specific technical challenges. INL employees work cooperatively with researchers and technical staff from the university and industrial sectors to further development of emerging technologies. In this multinational global economy, INL is contributing to the development of the next generation of engineers and scientists by licensing software to educational institutions throughout the world. This report is a catalog of select INL technology transfer and commercialization transactions and research agreements that were executed during this past year. The size and diversity of INL technical resources, coupled with the large number of relationships with other organizations, virtually ensures that a report of this nature will fail to capture all interactions. Recognizing this limitation, this report focuses on transactions that are specifically authorized by technology transfer legislation (and corresponding contractual provisions) or involve the transfer of legal rights to technology to other parties. This report was compiled from primary records, which were readily available to the INL’s Technology Deployment and Contracts Management Offices. Accomplishments cataloged in the report reflect the achievements and creativity of the researchers, technicians, support staff, and operators of the INL workforce.

99 GENERAL AND MISCELLANEOUS↗

Post-Closure Report for Closed Resource Conservation and Recovery Act Corrective Action Units, Nevada National Security Site, Nevada: For Fiscal Year 2015 (October 2014–September 2015), Revision 0

This report serves as the combined annual report for post-closure activities for the following closed corrective action units (CAUs); CAU 90, Area 2 Bitcutter Containment; CAU 91, Area 3 U-3fi Injection Well; CAU 92, Area 6 Decon Pond Facility; CAU 110, Area 3 WMD U-3ax/bl Crater; CAU 111, Area 5 WMD Retired Mixed Waste Pits; and CAU 112, Area 23 Hazardous Waste Trenches. This report covers fiscal year 2015 (October 2014 through September 2015). The post-closure requirements for these sites are described in Resource Conservation and Recovery Act Permit Number NEV HW0101 and are summarized in each CAU-specific section in Section 1.0 of this report. The results of the inspections, a summary of maintenance activities, and an evaluation of monitoring data are presented in this report.

54 ENVIRONMENTAL SCIENCES↗