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Search indexed NASA NTRS and DOE OSTI research on propulsion, heat transfer, battery materials and energy systems. Follow report and document links to the original sources.
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Genomic and Molecular Landscape of DNA Damage Repair Deficiency across The Cancer Genome Atlas
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Automated Design by Structure-Based Stabilization and Consensus Repair to Achieve Prefusion-Closed E
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Spontaneous Regression of Mismatch Repair-Deficient Colon Cancer: A Case Series
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Lateral deformation behaviour of structural internal replacement pipe repair systems
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Day and night variations in the repair of ionizing-radiation-induced DNA damage in mouse splenocytes
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Envisioning how the prototypic molecular machine TFIIH functions in transcription initiation and DNA repair
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Impact of DNA sequences on DNA ?opening? by the Rad4/XPC nucleotide excision repair complex
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Analysis of failure modes in pipe-in-pipe repair systems for water and gas pipelines
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Effects of the legacy pipe ends on the behaviour of pipe-in-pipe repair systems under internal pressure
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Effect of a personalized intensive dietary intervention on base excision repair (BER) in colorectal cancer patients: Results from a randomized controlled trial
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Self-Repairing Polymer-Modified Cements for High Temperature Geothermal and Fossil Energy Applications
In this work five novel polymer-cement composite formulations were prepared and evaluated as potential cementitious material alternatives to conventional wellbore cement. These cement composites were cured at 200 °C and their mechanical properties, including compressive strength, Young modulus, shear bond strength to steel casing, and self-healing and re-adhering (to steel) capability. Thermal stability was also evaluated by curing these cement materials at 200 °C for up to one month followed by determining their mineralogy and chemical composition by X-ray diffraction spectroscopy, 13C NMR, and total organic carbon. Permeability analysis was performed before and after healing a longitudinal fracture on unmodified cements and polymer-cement composites with the later showing lower (2nd/1st) permeability ratios with respect to base cements. Furthermore, a reduction in permeability of up to 80X on average with respect to their unmodified (base) cement, was observed in two polymer-cement formulations suggesting that the introduction of these polymers bring about self-healing capability. Two of the best performing polymer-cement composites were exposed to 30-day curing period at 200 °C showing that their self-healing capability is maintained. The composite stability is associated to the fact that the polymer material is stable as demonstrated by total organic carbon and NMR spectroscopy. These advanced polymer-cement composites with higher ductility and self-healing capability could be used as alternative wellbore cement materials for geothermal and fossil energy applications.
Dimethyl Sulfoxide Prevents Radiation-Induced Oral Mucositis Through Facilitating DNA Double-Strand Break Repair in Epithelial Stem Cells
Oral mucositis is one of the most prevalent side effects in patients undergoing radiation therapy for head and neck cancers. Current therapeutic agents such as palifermin recombinant human keratinocyte growth factor and amifostine do not efficiently or fully prevent mucositis. Dimethyl sulfoxide (DMSO), a free-radical scavenger, has shown therapeutic benefits in many preclinical and clinical studies. This study aimed to investigate the efficacy of DMSO in a clinically relevant mouse model of acute, radiation-induced oral mucositis.
Autoinhibition is not a universal feature of transcription-repair coupling factors
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Damage-induced hydrolyses modelling of biodegradable polymers for tendons and ligaments repair
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Lime binders for the repair of historic buildings: Considerations for CO2 abatement
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