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At least 703 records · Page 39

Individual Differences in Response to Sleep Deprivation: Assessment of Fatigue Following Sleep Loss

Previous work has indicated that a small but significant number of participants in sleep deprivation studies or in simulated shift work experiments manifests an exaggerated performance decrement when they reach a critical point in the experiment, usually near the trough of the circadian cycle or the middle of the night. Those who show this exaggerated response do not appear to differ from other non-nal volunteers in any substantial way according to usual screening criteria or baseline values. The present study aims to examine factors that may provide the basis for this extreme response. We propose that a preexisting sleep deficit-as manifested by low values on the Multiple Sleep Latency Test (MSLT)-may account for extreme responders. It has been shown that among normal volunteers screened for a variety of studies, approximately 20 to 25 percent show low (< 6 minutes) MSLT scores on a consistent basis, whereas a like proportion shows consistently high MSLT scores (> 13 minutes). Additionally, studies by this group have indicated that subjects with low MSLT scores may suffer from chronic insufficient sleep, as further substantiated by the finding that they have consistently higher nocturnal sleep efficiency and that their MSLT scores rise to normal values when sleep is extended. We hypothesize that the short MSLT subjects have a significant long-term sleep deficit that leads to a marked intolerance for sleep deprivation or shift work. We further suggest that this sleep debt may signify an increased sleep need in these individuals that is not met either due to personal preference or to societal pressures (or both). If this speculation is accurate, then we predict that the tolerance for sleep deprivation in such individuals can be increased by "pretreatment" with sleep extension. Thus, the present study is designed to test the following two hypotheses: (1) subjects with nominal sleep patterns who have low MSLT scores (e.g., Sleepy subjects) will show an exaggerated response (performance decrement) to sleep loss compared to subjects who have high MSLT scores (Alert subjects) on a nominal sleep schedule; (2) when permitted to extend sleep--thus discharging their sleep debt-the Sleepy subjects will show a sleep-loss response resembling that of the Alert subjects.

Carskadon, Mary A.↗

Individual Differences in Response to Sleep Deprivation: Assessment of Fatigue Following Sleep Loss

Previous work has indicated that a small but significant number of participants in sleep deprivation studies or in simulated shift work experiments manifests an exaggerated performance decrement when they reach a critical point in the experiment, usually near the trough of the circadian cycle or the middle of the night. Those who show this exaggerated response do not appear to differ from other normal volunteers in any substantial way according to usual screening criteria or baseline values. The present study aims to examine factors that may provide the basis for this extreme response. We propose that a preexisting sleep deficit-as manifested by low values on the Multiple Sleep Latency Test (MSLT)-may account for extreme responders. Roth and colleagues (1993) have shown that among normal volunteers screened for a variety of studies, approximately 20 to 25 percent show low (< or = 6 minutes) MSLT scores on a consistent basis, whereas a like proportion shows consistently high MSLT scores (> or = 13 minutes). Additionally, studies by this group have indicated that subjects with low MSLT scores may suffer from chronic insufficient sleep (Roth et al., 1993), as further substantiated by the finding that they have consistently higher nocturnal sleep efficiency and that their MSLT scores rise to normal values when sleep is extended (Roehrs et al., 1996). We hypothesize that the short MSLT subjects have a significant long-term sleep deficit that leads to a marked intolerance for sleep deprivation or shift work. We further suggest that this sleep debt may signify an increased sleep need in these individuals that is not met either due to personal preference or to societal pressures (or both). If this speculation is accurate, then we predict that the tolerance for sleep deprivation in such individuals can be increased by "pretreatment" with sleep extension. Thus, the present study is designed to test the following two hypotheses: subjects with nominal sleep patterns who have low MSLT scores (e.g., Sleepy subjects) will show an exaggerated response (performance decrement) to sleep loss compared to subjects who have high MSLT scores (Alert subjects) on a nominal sleep schedule. When permitted to extend sleep-thus discharging their sleep debt-the Sleepy subjects will show a sleep-loss response resembling that of the Alert subjects.

Carskadon, Mary A.↗

The Laser Communications Relay Demonstration Experiment Program

This paper elaborates on the Laser Communications Relay Demonstration (LCRD) Experiment Program, which will engage in a number of pre-determined experiments and also call upon a wide variety of experimenters to test new laser communications technology and techniques, and to gather valuable data. LCRD is a joint project between NASA's Goddard Space Flight Center (GSFC), the Jet Propulsion Laboratory (JPL), and the Massachusetts Institute of Technology Lincoln Laboratory (MIT LL). LCRD will test the functionality in various settings and scenarios of optical communications links from a GEO (Geosynchronous Earth Orbit) payload to ground stations in Southern California and Hawaii over a two-year period following launch in 2019. The LCRD investigator team will execute numerous experiments to test critical aspects of laser communications activities over real links and systems, collecting data on the effects of atmospheric turbulence and weather on performance and communications availability. LCRD will also incorporate emulations of target scenarios, including direct-to-Earth (DTE) links from user spacecraft and optical relay providers supporting user spacecraft. To supplement and expand upon the results of these experiments, the project also includes a Guest Experimenters Program, which encourages individuals and groups from government agencies, academia and industry to propose diverse experiment ideas.

Optical↗

The Laser Communications Relay Demonstration Experiment Program

This paper elaborates on the Laser Communications Relay Demonstration (LCRD) Experiment Program, which will engage in a number of pre-determined experiments and also call upon a wide variety of experimenters to test new laser communications technology and techniques, and to gather valuable data. LCRD is a joint project between NASAs Goddard Space Flight Center (GSFC), the Jet Propulsion Laboratory (JPL), and the Massachusetts Institute of Technology Lincoln Laboratory (MIT LL). LCRD will test the functionality in various settings and scenarios of optical communications links from a GEO payload to ground stations in Southern California and Hawaii over a two-year period following launch in 2019. The LCRD investigator team will execute numerous experiments to test critical aspects of laser communications activities over real links and systems, collecting data on the effects of atmospheric turbulence and weather on performance and communications availability. LCRD will also incorporate emulations of target scenarios, including direct-to-Earth (DTE) links from user spacecraft and optical relay providers supporting user spacecraft. To supplement and expand upon the results of these experiments, the project also includes a Guest Experimenters Program, which encourages individuals and groups from government agencies, academia and industry to propose diverse experiment ideas.

Optical Communicatio↗

ISS-Crystal Growth of Photorefractive Materials (BSO): Critical Design Issues for Optimized Data Extraction from Space Experiments

Realization of the full potential of photorefractive materials in device technology is seriously impeded by our inability to achieve controlled formation of critical defects during single crystal growth and by difficulties in meeting the required degree of compositional uniformity on a micro-scale over macroscopic dimensions. The exact nature and origin of the critical defects which control photorefractivity could not as yet be identified because of gravitational interference. There exists, however, strong evidence that the density of defect formation and their spatial distribution are adversely affected by gravitational interference which precludes the establishment of quantifiable and controllable heat and mass transfer conditions during crystal growth. The current, NASA sponsored research at MIT is directed at establishing a basis for the development of a comprehensive approach to the optimization of property control during melt growth of photorefractive materials, making use of the m-g environment, provided in the International Space Station. The objectives to be pursued in m-g research on photorefractive BSO (Bi12SiO20) are: (a) identification of the x-level(s) responsible for photorefractivity in undoped BSO; (b) development of approaches leading to the control of x-level formation at uniform spatial distribution; (c) development of doping and processing procedures for optimization of the critical, application specific parameters, spectral response, sensitivity, response time and matrix stability. The presentation will focus on: the rationale for the justification of the space experiment, ground-based development efforts, design considerations for the space experiments, strategic plan of the space experiments, and approaches to the quantitative analysis of the space experiments.

Hyers, Robert W.↗

Calculation of Critical Heat Flux Using an Inverse Heat Transfer Method to Support TREAT Experiment Analysis

Heat transfer between cladding and coolant during transient scenarios remains a critical area of uncertainty in understanding nuclear reactor safety. To advance the understanding of transient and accident scenarios involving critical heat flux (CHF), an in-pile experiment for the Transient Reactor Test (TREAT) facility at Idaho National Laboratory was developed. The experiment named CHF-Static Environment Rodlet Transient Test Apparatus (CHF-SERTTA), consists of a hollow borated stainless steel heater rod submerged in a static water pool which is heated via the (n, a) reaction in boron-10. This paper presents a novel inverse heat transfer method to determine CHF by using the optimization and uncertainty software DAKOTA to calibrate a RELAP5-3D model of CHF-SERTTA to temperature measurements obtained from a thermocouple welded to the surface of the rod.

22 GENERAL STUDIES OF NUCLEAR REACTORS↗

Generalized Bayesian Framework for Evaluation of Integral Benchmark Experiments

A recently published generalized Bayesian optimization framework has provided a way to retract any or all of the three common assumptions underlying the conventional Generalized Linear Least Squares (GLLS) optimization method based on the concepts introduced in Ref. [2]. These assumptions are: 1. Perfection: The model used for data evaluation and the prior probability distribution function (PDF) of generalized data are perfect. 2. Normality: The prior and posterior PDF are normal. 3. Linearity: The model is linear. In this work we outline how the framework in [1] could be directly adopted for improved evaluation of nuclear criticality integral benchmark experiments (IBEs) by: 1. Removing the first assumption alone by utilizing the concept of imperfections introduced in [1] to enable evaluation in the presence of discrepancies between the data and model or of missing covariance information by a GLLS method that will be seen as a generalization of the conventional GLLS method employed by the TSURFER code, and by 2. Removing the remaining two assumptions by implementing a Markov Chain Monte Carlo method for computation of the posterior PDF in the SAMPLER code, where TSURFER and SAMPLER are the uncertainty quantification (UQ) codes for IBEs in the SCALE code system based on the GLLS and the stochastic method, respectively. The graphic in Figure 1 categorizes the methods discussed in terms of the assumptions that they employ to determine posterior PDFs.

73 NUCLEAR PHYSICS AND RADIATION PHYSICS↗

Generalized Bayesian Framework for Evaluation of Integral Benchmark Experiments

A recently published generalized Bayesian optimization framework has provided a way to retract any or all of the three common assumptions underlying the conventional Generalized Linear Least Squares (GLLS) optimization method based on the concepts introduced in reference two. These assumptions are: 1. Perfection: The model used for data evaluation and the prior probability distribution function (PDF) of generalized* data are perfect; 2. Normality: The prior and posterior PDF are normal; and 3. Linearity: The model is linear. In this work we outline how the framework in 1 could be directly adopted for improved evaluation of nuclear criticality integral benchmark experiments (IBEs) by: 1. Removing the first assumption alone by utilizing the concept of imperfections introduced in 1 to enable evaluation in the presence of discrepancies between the data and model or of missing covariance information by a GLLS method that will be seen as a generalization of the conventional GLLS method employed by the TSURFER code, and by 2. Removing the remaining two assumptions by implement- ing a Markov Chain Monte Carlo method for computation of the posterior PDF in the SAMPLER code, where TSURFER and SAMPLER are the uncertainty quantification (UQ) codes for IBEs in the SCALE code system based on the GLLS, and the stochastic method, respectively.

73 NUCLEAR PHYSICS AND RADIATION PHYSICS↗

Research on computer aided testing of pilot response to critical in-flight events

Experiments on pilot decision making are described. The development of models of pilot decision making in critical in flight events (CIFE) are emphasized. The following tests are reported on the development of: (1) a frame system representation describing how pilots use their knowledge in a fault diagnosis task; (2) assessment of script norms, distance measures, and Markov models developed from computer aided testing (CAT) data; and (3) performance ranking of subject data. It is demonstrated that interactive computer aided testing either by touch CRT's or personal computers is a useful research and training device for measuring pilot information management in diagnosing system failures in simulated flight situations. Performance is dictated by knowledge of aircraft sybsystems, initial pilot structuring of the failure symptoms and efficient testing of plausible causal hypotheses.

Giffin, W. C.↗

Experimental Considerations for Ground-Based Testing of Lunar Construction Technologies

NASA’s Moon-To-Mars Planetary Autonomous Construction Technology (MMPACT) project seeks to research, develop, and demonstrate lunar surface construction capabilities - Quantification of lunar regolith’s geotechnical properties allows for effective prediction of forces and displacement during excavation and construction and is critical to facilitating regolith sintering capabilities all of which benefit lunar infrastructure plans - Knowledge of shear strength, Mohr-Coulomb cohesion, angle of internal friction, bearing strength, bulk density, etc. is needed - Ground-based testing of various lunar simulants with relevant hardware (e.g., robotic arm tools) enables validation of technology choices, tool paths, and lunar surface construction activities - Use of Taguchi methods [1] will minimize the number of needed experiments to explore critical input parameter

Moon↗

The Need for Earth-Based Experiments to Inform Microbial Evolution on Planetary Surfaces

Introduction: Historically, the focus of planetary protection at NASA has been on unmanned, robotic missions. Such missions have paved the way for understanding how to implement planetary protection in a feasible and cost-sensitive way. However, with the introduction of crewed missions to Mars in the not-sodistant future, there is a need to better define and understand how to implement planetary protection under new circumstances, as well as understand the risk of contaminating Mars. One unavoidable fact is that microbes will go where humans go. Therefore, it is critical to understand how these microbes may (and will) impact our ability to conduct meaningful, reliable astrobiological science. Microorganisms have spent millions of years evolving to survive in extreme environments here on Earth. Already there are indications that microbes aboard the International Space Station evolve and adapt to life in low earth orbit. The microbes that are eventually taken to Mars with humans will also adapt, potentially causing harmful effects to crew and/or the planetary or astrobiological science conducted. Therefore, it is of critical interest that we evaluate and characterize the potential risks of microbial evolution on Mars. It is expected that microbes carried by humans will begin to evolve to new environments even before landing on Mars, during the several month cruise phase. Once landed, microbes will encounter different stressors within the crew habitats on Mars. During extravehicular activities, venting, or other release events, microbes will find their way out onto the Martian surface. The induced environments around crewed systems will create potentially-favorable conditions for microbes to continue evolving on Mars. Eventually, microbes may find their way beyond the close confines of the crewed area and continue evolving so as to fill new or distant niches on the Martian surface. It is challenging to replicate Martian environments here on Earth, making it nearly impossible to predict the evolutionary changes that microbes would undergo on Mars. But this work is critical. Serial passaging experiments performed by Richard Lenski on E. coli show the dramatic changes microbes can undergo even within a laboratory setting. Furthermore, experiments performed by Michael Baym also demonstrate the power of single mutations in microbial development of antibiotic resistance [3]. Long duration experiments should be performed on a suite of microbes exposed to environments likely to be experienced on the Martian surface. While simulating space environments can be challenging, facilities exist that can achieve individual and combinatorial environmental conditions to simulate space and planetary conditions. Such chambers should be employed for microbial studies. Currently, at the Marshall Space Flight Center, we have used various stressors like drying, vacuum, proton radiation, and ultraviolet light both separately and in combination, to evaluate the survival of cleanroom microbes. Shockingly, several non-spore forming isolates have demonstrated the ability to survive many extreme conditions (manuscript in preparation). These short duration exposures must be augmented with larger and more gradual studies to replicate what microbes might experience in the transition from cruise, to surface habitats, to induced surface environments, and finally true Martian environments. While no Earth-based experiment can perfectly replicate the Martian environment, nor could we test every possible microbe in simulation experimental regimes, efforts should be made to examine the evolutionary potential of the “usual suspects” seen on the ISS or in other crewed environments to begin to fill this important knowledge gap.

Chelsi D. Cassilly↗

Nuclear Archival Electronic Database

The Nuclear Archival Electronic Database (NAED) supports a work scope that has been focused on providing a framework for and preserving key experimental programs and experiences which are critical to the licensing basis of currently operating nuclear reactors or which could be used in the safety basis for the next generation of reactors. It aims at preserving the results of experimental programs for the safety of light water cooled and advanced reactors by locating and documenting, to the extent possible, where the experimental test information for these programs has been archived. The NAED is a compilation of the following: (a) list of experiments or experiences categorized by coolant type, (b) results of an information search, and documentation, of the experiments and experiences that are already considered archived and (c) results of a deep dive and interview on a single experimental program or experience. The intent is to use the NAED as a technology source document by reactor vendors, regulators, and utility personnel.

22 GENERAL STUDIES OF NUCLEAR REACTORS↗

LUNAR REGOLITH:SMALL SCALE ROBOTIC SITE PREPARATION AND GEOTECHNICAL EXPERIMENTSWITH SCOOPS

NASA’s Moon-To-Mars Planetary Autonomous Construction Technology (MMPACT) project seeks to research, develop, and demonstrate lunar surface construction capabilities. Quantification of lunar regolith’s geotechnical properties allows for effective prediction of forces and displacement during excavation and construction and is critical to facilitating regolith sintering capabilities all of which benefit lunar infrastructure plans. Knowledge of shear strength, Mohr-Coulomb cohesion, angle of internal friction, bearing strength, bulk density, etc. is needed. The use of ground-based testing of various lunar simulants with relevant hardware (e.g., robotic arm tools) enables validation of technology choices, tool paths, and lunar surface construction activities. In addition, the use of Taguchi methods will minimize the number of needed experiments to explore critical input parameters.

R. P. Mueller↗

The Mu2e Experiment (Final Technical Report)

This is the final technical report for the initial two year funding period to start a new collaboration group at the University of California Davis for the Mu2e Experiment at Fermilab. The goal if the Mu2e Experiment is to search for the conversion to an electron of a muon that has been captured by an aluminum nucleus. While this process is effectively forbidden in the Standard Model, it is a virtually universal feature of models beyond the Standard Model. Mu2e will probe the reaction with a sensitivity that is roughly four orders of magnitude better than the best previous measurement. This range of sensitivity probes most of the parameters space of supersymmetry, and any signal will be unambigious proof of physics beyond the Standard Model. Professor Prebys was one of the founding members and first spokespersons of the Mu2e Experiment during his time af Fermilab. He came to UC Davis in 2017 with the goal of starting a Mu2e collaborating group here, and this grant has funded that effort. Specifically, in addition to summer salary, it has supported a graduate student and a postdoc, both of whom are now permanently stationed at Fermilab. During this time, their work has focused primarily on the understanding to the formation of the proton bunches in Fermilab Recycler, as this is critical to the experiment. This has included both measurements and simulations.

43 PARTICLE ACCELERATORS↗

Analytical and numerical investigation of structural response of compliant wall materials, part 1

Surface motion of compliant walls in drag reduction experiments was analyzed. Critical comparison was made between the dynamic motion of the structure and the postulated mechanism of drag reduction. The spectrum of surface motion indicated that membranes over deep cavities respond at low frequencies and large wavelengths. The membrane over a deep cavity is therefore found not to yield the desired response predicted by the postulated mechanism. The membrane over a thin air gap is found to act as a wavelength chopper, and analysis of the nonlinear response of that compliant surface indicated its possible suitability for compliant wall experiments. Periodic structures are found to lock in the desired wavelengths of motion, and it was shown that at least in Kramer's initial experiments they produced high frequency surface motions. Laminated structures are found to be very ineffective as compliant models, except when there is no bonding between the membrane and the backing. Computer programs developed for these analyses are documented.

Balasubramanian, R.↗

Experience report: Using formal methods for requirements analysis of critical spacecraft software

Formal specification and analysis of requirements continues to gain support as a method for producing more reliable software. However, the introduction of formal methods to a large software project is difficult, due in part to the unfamiliarity of the specification languages and the lack of graphics. This paper reports results of an investigation into the effectiveness of formal methods as an aid to the requirements analysis of critical, system-level fault-protection software on a spacecraft currently under development. Our experience indicates that formal specification and analysis can enhance the accuracy of the requirements and add assurance prior to design development in this domain. The work described here is part of a larger, NASA-funded research project whose purpose is to use formal-methods techniques to improve the quality of software in space applications. The demonstration project described here is part of the effort to evaluate experimentally the effectiveness of supplementing traditional engineering approaches to requirements specification with the more rigorous specification and analysis available with formal methods.

Lutz, Robyn R.↗

Experience Report: Using Formal Methods for Requirements Analysis of Critical Spacecraft Software

Formal specification and analysis of requirements continues to gain support as a method for producing more reliable software. However, the introduction of formal methods to a large software project is difficult, due in part to the unfamiliarity of the specification languages and the lack of graphics. This paper reports results of an investigation into the effectiveness of formal methods as an aid to the requirements analysis of critical, system-level fault-protection software on a spacecraft currently under development. Our experience indicates that formal specification and analysis can enhance the accuracy of the requirements and add assurance prior to design development in this domain.

Formal↗

Calibrating Atmospheric Delay for the Cassini Gravitational Wave Experiment

The Cassini spacecraft together with one of the stations of the Deep Space Network (DSN) have been instrumented to carry out extremely precise Doppler tracking that will be used to search for the direct evidence of Gravitational radiation passing through our solar system. The two-way communications link between the ground antenna and the spacecraft constitute an "antenna" for gravitational waves that would perturb the phase of the RF signal in the link. The experiments will be carried out during the long cruise phase of the spacecraft on its journey to Saturn and will be sensitive to gravitational wave perturbations larger than the noise level fluctuations of 3 x 10(exp -15) as measured in the Allan Standard Deviation domain. The use of simultaneous, coherent X- and Ka-Band up and down signals will reduce the errors associated with charged particle fluctuations in the interplanetary medium and Earth's ionosphere to a negligible level. The primary fluctuations in the phase of the signals both to and from the spacecraft are expected to be caused by fluctuations in water vapor in the Earth's atmosphere We have designed and are testing a new atmospheric calibration system (with duplicate components) to sense line-of-sight water vapor and its physical temperature with a goal of calibrating 95% or more of tropospheric path delay fluctuations during the Cassini Gravitational Wave Experiment (GWE). The critical component of the calibration system consists of a newly designed water vapor radiometer having a I degree sensing beamwidth and 0.01 K brightness temperature stability over hour time scales. Auxiliary instrumentation includes a microwave temperature profiler to retrieve the vertical distribution of the vapor physical temperature, and surface meteorology. A detailed error budget has been developed to account for all of the possible sources of error during calibration of the GWE and will be discussed. Two identical calibration systems have been constructed in order to provide capability as well as backup during the actual GWE experiment. We will report on side-by-side testing of the vapor and temperature sensing components of this calibrations system as well as a comparison with a short baseline radio interferometric measurement at our Goldstone complex.

Resch, G. M.↗