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At least 685 records · Page 38

Apoptosis: a mechanism contributing to remodeling of skeletal muscle in response to hindlimb unweighting

The role of apoptosis in the elimination of myonuclei during hindlimb unloading-induced atrophy and the inhibition of apoptosis in the prevention of muscle atrophy were examined. The number of nuclei demonstrating double-stranded DNA fragmentation seen by terminal deoxynucleotidyl transferase (TDT) histochemical staining, an indicator of apoptosis, was significantly increased after 14 days of suspension. Double staining with TDT and antilaminin immunohistochemistry revealed that some TDT-positive nuclei were within the fiber lamina and were most likely myonuclei. The number of fibers containing morphologically abnormal nuclei was also significantly greater in suspended compared with control rats. Combined treatment with growth hormone and insulin-like growth factor I (GH/ IGF-I) and resistance exercise attenuated the increase in TDT-positive nuclei (approximately 26%, P > 0.05) and significantly decreased the number of fibers with morphologically abnormal nuclei. The data suggest that 1) "programmed nuclear death" contributes to the elimination of myonuclei and/or satellite cells from atrophying fibers, and 2) GH/IGF-I administration plus muscle loading ameliorates the apoptosis associated with hindlimb unloading.

Non-NASA Center↗

First simultaneous global QCD analysis of dihadron fragmentation functions and transversity parton distribution functions

We perform a comprehensive study within quantum chromodynamics (QCD) of dihadron observables in electron-positron annihilation, semi-inclusive deep-inelastic scattering, and proton-proton collisions, including recent cross section data from Belle and azimuthal asymmetries from STAR. We extract simultaneously for the first time π + π − dihadron fragmentation functions (DiFFs) and the nucleon transversity distributions for up and down quarks as well as antiquarks. For the transversity distributions we impose their small- x asymptotic behavior and the Soffer bound. In addition, we utilize a new definition of DiFFs that has a number density interpretation to then calculate expectation values for the dihadron invariant mass and momentum fraction. Furthermore, we investigate the compatibility of our transversity results with those from single-hadron fragmentation (from a transverse momentum dependent/collinear twist-3 framework) and the nucleon tensor charges computed in lattice QCD. We find a universal nature to all of this available information. Future measurements of dihadron production can significantly further this research, especially, as we show, those that are sensitive to the region of large parton momentum fractions. Published by the American Physical Society 2024

73 NUCLEAR PHYSICS AND RADIATION PHYSICS↗

Optical model methods of predicting nuclide production from spallation reactions

Quantum mechanical optical model methods for calculating isotope production cross sections from the spallation of heavy nuclei by high-energy protons are developed from a modified abrasion-ablation collision formalism. The abrasion step is treated quantum-mechanically as a knockout process which leaves the residual prefragment nucleus in an excited state. In ablation the prefragment deexcites to produce the final fragment. The excitation energies of the prefragments are estimated from a combination of liquid drop and frictional-spectator interaction considerations. Estimates of elemental and isotopic production cross sections are in good agreement with recently published cross section measurements.

NASA Discipline Radiation Health↗

New physics particles mixing with mesons: Production in the fragmentation chain

A class of extensions to the Standard Model adds hypothetical long-lived particles (LLPs) that have mass- or kinetic-mixing with neutral mesons, such as pions or rho mesons. The mixing can contribute significantly to the production of LLPs at proton accelerator experiments, and no consistent description of these production modes exists in the literature. In this paper, we develop a framework for studying different LLPs—dark photons, vector mediators coupled to the baryon current, and axionlike particles with different coupling patterns. In particular, we implement the production mechanisms in PYTHIA 8, study how the overall flux and kinematic distributions depend on the LLP’s mass, and compare various subprocesses where the mixing contributes—proton bremsstrahlung, meson decay, and production in the fragmentation chain. We find that our new description of LLP production predicts an integrated flux that differs from current approaches by one to two orders of magnitude, and highlight the unavoidable theoretical uncertainties coming from poor knowledge of the properties of heavy mesons.

72 PHYSICS OF ELEMENTARY PARTICLES AND FIELDS↗

Enhanced Deuteron Coalescence Probability in Jets

The transverse-momentum ($p_T$) spectra and coalescence parameters $B_2$ of (anti)deuterons are measured in p-p collisions at $\sqrt{s}=13$ $\text{TeV}$ for the first time in and out of jets. In this measurement, the direction of the leading particle with the highest $p_T$ in the event ($p^{lead}_T > 5 GeV/c$) is used as an approximation for the jet axis. The event is consequently divided into three azimuthal regions, and the jet signal is obtained as the difference between the toward region, that contains jet fragmentation products in addition to the underlying event (UE), and the transverse region, which is dominated by the UE. The coalescence parameter in the jet is found to be approximately a factor of 10 larger than that in the underlying event. This experimental observation is consistent with the coalescence picture and can be attributed to the smaller average phase-space distance between nucleons in the jet cone as compared with the underlying event. The results presented in this Letter are compared to predictions from a simple nucleon coalescence model, where the phase-space distributions of nucleons are generated using pythia8 with the Monash 2013 tuning, and to predictions from a deuteron production model based on ordinary nuclear reactions with parametrized energy-dependent cross sections tuned on data. The latter model is implemented in pythia8.3. Both models reproduce the observed large difference between in-jet and out-of-jet coalescence parameters, although the almost flat trend of the $B^{Jet}_2$ is not reproduced by the models, which instead give a decreasing trend.

72 PHYSICS OF ELEMENTARY PARTICLES AND FIELDS↗

Transverse momentum-dependent heavy-quark fragmentation at next-to-leading order

The transverse momentum-dependent fragmentation functions (TMD FFs) of heavy (bottom and charm) quarks, which we recently introduced, are universal building blocks that enter predictions for a large number of observables involving final-state heavy quarks or hadrons. They enable the extension of fixed-order subtraction schemes to quasi-collinear limits, and are of particular interest in their own right as probes of the nonperturbative dynamics of hadronization. In this paper we calculate all TMD FFs involving heavy quarks and the associated TMD matrix element in heavy-quark effective theory (HQET) to next-to-leading order in the strong interaction. Our results confirm the renormalization properties, large-mass, and small-mass consistency relations predicted in our earlier work. We also derive and confirm a prediction for the large-z behavior of the heavy-quark TMD FF by extending, for the first time, the formalism of joint resummation to capture quark mass effects in heavy-quark fragmentation. Our final results in position space agree with those of a recent calculation by another group that used a highly orthogonal organization of singularities in the intermediate momentum-space steps, providing a strong independent cross check. As an immediate application, we present the complete quark mass dependence of the energy-energy correlator (EEC) in the back-to-back limit at $\mathcal{O}\left({\alpha}_s\right)$.

73 NUCLEAR PHYSICS AND RADIATION PHYSICS↗

Neutron response of the TLYC scintillator

The response of the recently developed Tl 2 LiYCl 6 (Ce) scintillator to neutrons was measured and the 35 Cl(n,p) channel observed in the material for the first time. The scintillator was exposed to a 252 Cf source mounted within a parallel-plate avalanche counter for fission-fragment coincident measurements. Proton- and -like events are selected with the pulse-shape discrimination technique. Additionally, comparison of energy-deposition and time-of-flight allows the quenching of the different channels to be assessed. The 6 Li(n,t) channel is found to have its energy quenched to 37(1)% relative to -ray detection, while the proton energy deposition spectrum is quenched to 60(1)%.

73 NUCLEAR PHYSICS AND RADIATION PHYSICS↗

LET analyses of biological damage during solar particle events

The effects of nuclear reactions on integral low-linear-energy-transfer (LET) protons spectra are studied, behind typical levels of spacecraft and body shielding, for the historically largest flares using the high-energy transport code BRYNTRN in conjunction with several biological damage models. The cellular track model of Katz provides an accurate description of cellular damage from heavy ion exposure. The track model is applied with BRYNTRN to provide a LET decomposition of survival and transformation rates for solar proton events. In addition, a fluence-based risk coefficient formalism is used to estimate Harderian gland-tumor induction in rodents and cataractogenesis in rabbits from solar flares, and a LET analysis is used to assess the relative contribution from target fragments on these biological endpoints.

Cucinotta, Francis A.↗

Quantifying uncertainties on fission fragment mass yields with mixture density networks

Probabilistic machine learning techniques can learn both complex relations between input features and output quantities of interest as well as take into account stochasticity or uncertainty within a data set. In this initial work, we explore the use of one such probabilistic network, the mixture density network (MDN), to reproduce fission yields and their uncertainties. In this paper, we study mass yields for the spontaneous fission of 252 Cf, exploring the number of training samples needed for converged predictions, how different levels of uncertainty propagate from the training set to the MDN predictions, and how well physical constraints of the yields—such as normalization and symmetry—are upheld by the algorithm. Finally, we test the ability of the MDN to interpolate between and extrapolate beyond samples in the training set using energy-dependent mass yields for the neutron-induced fission on 235 U. The MDN provides a reliable way to include and predict uncertainties and is a promising path forward for supplementing sparse sets of nuclear data.

72 PHYSICS OF ELEMENTARY PARTICLES AND FIELDS↗

Projection-to-Born-improved subtractions at NNLO

While the current frontier in fixed-order precision for collider observables is N 3 LO, important steps are necessary to consolidate NNLO cross-section predictions with improved stability and efficiency. Slicing methods have been successfully applied to obtain NNLO and N 3 LO predictions, but have shown poor performance in the presence of fiducial cuts due to large kinematical power corrections. In this paper we implement Projection-to-Born-improved q T (P2B q T ) and jettiness (P2Bτ 0 ) subtractions for a large class of color singlet processes in MCFM. This method allows for the efficient evaluation of fiducial power corrections in any non-local subtraction scheme using a Projection-to-Born subtraction. We demonstrate the significant numerical improvements of this method based on fiducial Drell-Yan and Higgs cross-sections. Moreover, with fiducial power corrections removed via this method, the leading-logarithmic power corrections that have only been calculated without fiducial cuts can be included, further improving the calculations. For di-photon production with photon isolation, we devise a novel method in combination with P2B-improved subtractions, which we name P2B γ τ 0 , and P2B γ q T for the two subtraction schemes, respectively. This method allows the inclusion of both fiducial power corrections due to kinematic cuts on the photons and a set of isolation power corrections in the fragmentation channel where a quark may enter the isolation cone. We find significant improvements in the convergence of NNLO di-photon cross-sections with photon isolation cuts, demonstrating that it is possible to achieve a stable and efficient calculation of di-photon cross-sections using slicing methods.

72 PHYSICS OF ELEMENTARY PARTICLES AND FIELDS↗

Calculations of hadronic dissociation of 28Si projectiles at 14.6A GeV by nucleon emission

An optical potential abrasion-ablation collision model is used to calculate hadronic dissociation cross sections for one, two, and three nucleon removal for the first time for a 14.6A GeV 28Si beam fragmenting in aluminum, tin, and lead targets. These estimates are compared with recent semi-inclusive measurements. Significant differences between some calculated and measured semi-inclusive cross sections exist which cannot be resolved without measurements of the exclusive channel hadronic cross sections. Calculations for each exclusive reaction channel contributing to the semi-inclusive cross sections are presented and discussed.

NASA Program Radiation Health↗

Nuclear Dynamics and Reactions in the Ab Initio Symmetry-Adapted Framework

We review the ab initio symmetry-adapted (SA) framework for determining the structure of stable and unstable nuclei, along with related electroweak, decay, and reaction processes. This framework utilizes the dominant symmetry of nuclear dynamics, the shape-related symplectic [Formula: see text] symmetry, which has been shown to emerge from first principles and to expose dominant degrees of freedom that are collective in nature, even in the lightest species or seemingly spherical states. This feature is illustrated for a broad scope of nuclei ranging from helium to titanium isotopes, enabled by recent developments of the ab initio SA no-core shell model expanded to the continuum through the use of the SA basis and that of the resonating group method. The review focuses on energies, electromagnetic transitions, quadrupole and magnetic moments, radii, form factors, and response function moments for ground-state rotational bands and giant resonances. The method also determines the structure of reaction fragments that is used to calculate decay widths and α-capture reactions for simulated X-ray burst abundance patterns, as well as nucleon–nucleus interactions for cross sections and other reaction observables.

Physics↗

GenConfig

SAND2025-04091O GenConfig converts a build name into a set of configuration flags or CMake fragment files for use with CMake. This is accomplished using ConfigKeywordParser and two configuration files. GenConfig is the main tool in a set of software libraries used for generating and configuring an environment and configuration flags. The tool uses other modules within the GenConfig family to ultimately parse and enable an environment that is ready for development from a given build name string. The unique algorithms used in GenConfig mainly pertain to validating the format and checking the existence of the given build string in the expected configuration .ini files. Sandia National Laboratories is a multimission laboratory managed and operated by National Technology & Engineering Solutions of Sandia, LLC, a wholly owned subsidiary of Honeywell International Inc., for the U.S. Department of Energy’s National Nuclear Security Administration under contract DE-NA0003525.

Gates, Jason↗

The effect of jet-induced medium excitation on Λ/ k 0 s in jet in Pb-Pb collisions

In this work, we use CoLBT-hydro model for simultaneous event-by-event simulations of jet propagation and hydrodynamics evolution of the bulk medium including jet-induced medium excitation. The final reconstructed jet in heavy-ion collision include not only hadrons from medium response for the deposited energy and momentum of hard partons, but also hadrons from the fragmentation and recombination process of in-medium hard partons. We carry out the study with CoLBT-hydro of medium modification of the Λ/ k 0 s in jet in Pb-Pb collisions at √sNN=2.76TeV. We qualitatively describe the enhancement of the Λ/ k 0 s ratio in jet in the intermediate pT region due to the contribution from jet-induced medium flow.

73 NUCLEAR PHYSICS AND RADIATION PHYSICS↗

Consideration of memory of spin and parity in the fissioning compound nucleus by applying the Hauser-Feshbach fission fragment decay model to photonuclear reactions

Prompt and β-delayed fission observables, such as the average number of prompt and delayed neutrons, the independent and cumulative fission product yields, and the prompt γ-ray energy spectra for the photonuclear reactions on 235,238 U and 239 Pu, are calculated with the Hauser-Feshbach fission fragment decay (HF 3 ⁢D) model and compared with available experimental data. Further, in the analysis of neutron-induced fission reactions to the case of photo-induced fission, an excellent reproduction of the delayed neutron yields supports a traditional assumption that the photo fission might be similar to the neutron-induced fission at the same excitation energies regardless of the spin and parity of the fissioning systems.

73 NUCLEAR PHYSICS AND RADIATION PHYSICS↗

Shallow-and-Deep Inelastic Scattering with Neutrinos

In ν/ν-Nucleon/Nucleus interactions Shallow Inelastic Scattering (SIS) is technically defined interms of the four-momentum transfer to the hadronic system as non-resonant meson productionwith predominantly lower Q 2 . This non-resonant meson production intermixes with resonantmeson production in a regime of similar effective hadronic mass W of the interaction. As Q 2 grows non-resonant interactions begin to take place with quarks within the nucleon indicating thestart of Deep Inelastic Scattering (DIS). To essentially separate this resonant plus non-resonantmeson production from DIS quark-fragmented meson production, a cut of 2 GeV in W of theinteractions is generally introduced. However, since experimentally mesons from resonance decaycannot be separated from non-resonant produced mesons, SIS for all practical purposes is definedas inclusive meson production that includes non-resonant plus resonant meson production andthe interference between them. NOTE, this is a mildly modified introduction and overview takenfrom the detailed summary of this topic referenced in the introduction.

72 PHYSICS OF ELEMENTARY PARTICLES AND FIELDS↗

Measurement of ω meson production in pp collisions at $\sqrt{s}$ = 13 TeV

The p T -differential cross section of ω meson production in pp collisions at $\sqrt{s}$ =13 TeV at midrapidity (|y| < 0.5) was measured with the ALICE detector at the LHC, covering an unprecedented transverse-momentum range of 1.6 < p T < 50 GeV/c. The meson is reconstructed via the ω → π + π − π 0 decay channel. The results are compared with various theoretical calculations: PYTHIA8.2 with the Monash 2013 tune overestimates the data by up to 50%, whereas good agreement is observed with Next-to-Leading Order (NLO) calculations incorporating ω fragmentation using a broken SU(3) model. The ω/π 0 ratio is presented and compared with theoretical calculations and the available measurements at lower collision energies. The presented data triples the p T ranges of previously available measurements. A constant ratio of C ω/π0 = 0.578 ± 0.006 (stat.) ± 0.013 (syst.) is found above a transverse momentum of 4 GeV/c, which is in agreement with previous findings at lower collision energies within the systematic and statistical uncertainties.

72 PHYSICS OF ELEMENTARY PARTICLES AND FIELDS↗

Instrumentation for correlated prompt n – γ emission studies in coincidence with fission fragments

Recent theoretical and experimental results have brought renewed interest and focus on the topic of fission fragment angular momentum. Measurements of neutrons and rays in coincidence with fission fragments remain the most valuable tool in the exploration of fission physics. To achieve these scientific goals, we have developed a system that combines a state-of-the-art fission fragment detector and n – γ radiation detectors. A new twin Frisch-gridded ionization chamber has been designed and constructed for use with a spontaneous fission source and an array of forty trans-stilbene organic scintillators (FS-3) at Argonne National Laboratory. The new ionization chamber design we present in this work aims at minimizing particle attenuation in the chamber walls, and provides a compact apparatus that can be fit inside existing experimental systems. The ionization chamber is capable of measuring fission fragment masses and kinetic energies, whereas the FS-3 provides neutron and γ-ray multiplicities and spectra. Here, the details of both detector assemblies are presented along with the first experimental results of this setup. Planned event-by-event analysis and future experiments are briefly discussed.

46 INSTRUMENTATION RELATED TO NUCLEAR SCIENCE AND ↗