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At least 685 records · Page 38

All sources NASA NTRS DOE OSTI

NASA NTRS1986

Dexamethasone regulates glutamine synthetase expression in rat skeletal muscles

The regulation of glutamine synthetase by glucocorticoids in rat skeletal muscles was studied. Administration of dexamethasone strikingly enhanced glutamine synthetase activity in plantaris and soleus muscles. The dexamethasone-mediated induction of glutamine synthetase activity was blocked to a significant extent by orally administered RU38486, a glucocorticoid antagonist, indicating the involvement of intracellular glucocorticoid receptors in the induction. Northern blot analysis revealed that dexamethasone-mediated enhancement of glutamine synthetase activity involves dramatically increased levels of glutamine synthetase mRNA. The induction of glutamine synthetase was selective in that glutaminase activity of soleus and plantaris muscles was not increased by dexamethasone. Furthermore, dexamethasone treatment resulted in only a small increase in glutamine synthetase activity in the heart. Accordingly, there was only a slight change in glutamine synthetase mRNA level in this tissue. Thus, glucocorticoids regulate glutamine synthetase gene expression in rat muscles at the transcriptional level via interaction with intracellular glutamine production by muscle and to mechanisms underlying glucocorticoid-induced muscle atrophy.

Max, Stephen R.↗

NASA NTRS1989

Temperature dependence of penetration depth in thin film niobium

A novel technique is presented which should allow precise determination of the temperature dependence of the inductance, and hence of the penetration depth, of superconducting niobium thin-film structures. Four niobium thin-film stripline inductors are arranged in a bridge configuration, and inductance differences are measured using a potentiometric technique with a SQUID (superconducting quantum interference device) as the null detector. Numerical simulations of the stripline inductances are presented which allow the performance of the measurement technique to be evaluated. The prediction of the two-fluid model for the penetration-depth temperature dependence is given for reduced temperatures of 0.3 to 0.9. The experimental apparatus and its resolution and accuracy are discussed.

More, N.↗

NASA NTRS1990

Electromechanical actuation for thrust vector control applications

At present, actuation systems for the Thrust Vector Control (TVC) for launch vehicles are hydraulic systems. The Advanced Launch System (ALS), a joint initiative between NASA and the Air Force, is a launch vehicle that is designed to be cost effective, highly reliable and operationally efficient with a goal of reducing the cost per pound to orbit. As part of this initiative, an electromechanical actuation system is being developed as an attractive alternative to the hydraulic systems used today. NASA-Lewis is developing and demonstrating an Induction Motor Controller Actuation System with a 40 hp peak rating. The controller will integrate 20 kHz resonant link Power Management and Distribution (PMAD) technology and Pulse Population Modulation (PPM) techniques to implement Field Oriented Vector Control (FOVC) of a new advanced induction motor. Through PPM, multiphase variable frequency, variable voltage waveforms can be synthesized from the 20 kHz source. FOVC shows that varying both the voltage and frequency and their ratio (V/F), permits independent control of both torque and speed while operating at maximum efficiency at any point on the torque-speed curve. The driver and the FOVC will be microprocessor controlled. For increased system reliability, a Built-in Test (BITE) capability will be included. This involves introducing testability into the design of a system such that testing is calibrated and exercised during the design, manufacturing, maintenance and prelaunch activities. An actuator will be integrated with the motor controller for performance testing of the EMA TVC system. The design and fabrication of the motor controller is being done by General Dynamics Space Systems Division. The University of Wisconsin-Madison will assist in the design of the advanced induction motor and in the implementation of the FOVC theory. A 75 hp electronically controlled dynamometer will be used to test the motor controller in all four quadrants of operation using flight type control algorithms. Integrated testing of the controller and actuator will be conducted at a facility yet to be named. The EMA system described above is discussed in detail.

Roth, Mary Ellen↗

NASA NTRS1990

High-T(sub c) squid application in medicine and geophysics

In the Laboratory a high-T(sub c) one-hole squid was built from Y1Ba2Cu3O(7-x) ceramics obtained by a standard procedure of solid state reaction. The ceramics with critical current density J(sub c) is greater than 100 A/sq cm was selected. In the middle of 10 x 10 x 2 mm ceramics pellet a 0.8 mm hole was drilled in which superconducting loop of the squid was located. Between the hole and the edge of the pellet a cut was mechanically filed out with a bridge inside it connecting the superconducting ring. A scheme of the magnetometer is presented. The resonant frequency shift of the tank circuit, the connection of the squid with this circuit, and the squid inductance are evaluated. One of the most interesting fields of the squid-based magnetometer application is biomagnetism, particularly, the human heart magnetocardiogram measuring. The low-temperature squids were used in this area and many interesting and important scientific results have been obtained. The observations have shown that the main noise contribution was not due to the squid but to the Earth's magnetic field variations, industrial inductions, and mainly to the vibrations caused by liquid nitrogen boiling and by vibrations of the box. Further attempts are needed to reduce the magnetic noise inductions. Nevertheless, the estimations promise the maximum signal/noise relation of the high-T(sub c) squid-magnetocardiometer to be not less than 10:1 in a bandwidth of 60 Hz. Apparently, such resolution would be enough not only for steady cardiogram reading but even for thin structure investigation at average technique application.

Polushkin, V. N.↗

NASA NTRS1989

Performance testing of a high frequency link converter for Space Station power distribution system

The testing of a brassboard version of a 20-kHz high-frequency ac voltage link prototype converter dynamics for Space Station application is presented. The converter is based on a three-phase six-pulse bridge concept. The testing includes details of the operation of the converter when it is driving an induction machine source/load. By adapting a field orientation controller (FOC) to the converter, four-quadrant operation of the induction machine from the converter has been achieved. Circuit modifications carried out to improve the performance of the converter are described. The performance of two 400-Hz induction machines powered by the converter with simple V/f regulation mode is reported. The testing and performance results for the converter utilizing the FOC, which provides the capability for rapid torque changes, speed reversal, and four-quadrant operation, are reported.

Sul, S. K.↗

NASA NTRS1991

Chemical waste disposal in space by plasma discharge

An inductively coupled plasma discharge apparatus operating at 13.56 MHz and with electrical power up to 2.5 kW was constructed. The efficiency of this device to destroy various gases expected to be carried aboard the Space Station was tested. By expressing the efficiency of the device in terms of G-value (the number of molecules decomposed per 100 eV of energy absorbed), the results are compared with known efficiencies of ionizing radiation to destroy these same gases. In the case of ammonia, it was found that in the inductively coupled device, the destruction efficiency, G(-NH3) varied from 6.0 to 32.0 molecules/100 eV, depending on conditions. It was also found that capacitatively coupled discharges were less efficient in destroying NH2 than the inductively coupled discharge. In the case NH2 destruction, it was found that the G(-NH3) was a qualitative guide to the efficiencies of plasmas. The plasma device was also used to destroy nitrous oxide and methane. It is shown how the G-value for the destruction of any gas can be computed theoretically from a knowledge of the electron velocity distribution, the various electron molecule scattering cross sections, and the rate constants for the reactions of secondary species.

Baird, James K.↗

NASA NTRS1991

A new probe for measuring small electric fields in plasmas

A dipolar double probe has been developed for in situ measurements of small electric fields in laboratory plasmas. The probe measures dc to ac electric fields (f values between 0 and 20 MHz) with high sensitivity (Emin about 10 microV/cm) and responds to both space charge electric fields and inductive electric fields. Using voltage-to-frequency conversion, the probe signal is obtained free of errors and loading effects by a transmission line. Various examples of useful applications for the new probe are presented, such as measurements of dc ambipolar fields, ac space-charge fields of ion acoustic waves, ac inductive fields of whistler waves, and mixed inductive and space-charge electric fields in current-carrying magnetoplasmas.

Stenzel, R. L.↗

NASA NTRS1991

Numerical and experimental study of curved and planar frequency selective surfaces with arbitrary illumination

A frequency selective surface (FSS) composed of apertures in a metallic sheet is known as the inductive FSS. The infinite inductive FSS theory is derived and the aperture fields are solved by a spectral domain formulation with method of moments solution. Both full domain and subsectional basis functions are studied. A locally planar technique (LPT) is used to determine the forward scattered field from a generally shaped inductive FSS with arbitrary illumination.

Caroglanian, Armen↗

NASA NTRS1991

High-T(c) squid application in medicine and geophysics

In our laboratory of high-T(sub c), a one-hole squid was built from Y1Ba2Cu3O(7-x) ceramics obtained by a standard procedure of solid state reaction. The ceramics with critical current density J(sub c) is greater than 100 A/sq cm was selected. In the middle of a 10 x 10 x 2 mm ceramics pellet, a 0.8 mm hole was drilled in which the superconducting loop of the squid was located. Between the hole and the edge of the pellet, a cut was mechanically filed out with a bridge inside it connecting the superconducting ring. A scheme of the magnetometer is presented. The resonant frequency shift of the tank circuit, the connection of the squid with this circuit, and the squid inductance are evaluated. One of the most interesting fields of the squid-based magnetometer application is biomagnetism, particularly, the human heart magnetocardiogram measuring. The low-temperature squids were used in this area and many interesting and important scientific results have been obtained. The observations have shown that the main noise contribution was not due to the squid but to the Earth's magnetic field variations, industrial inductions, and mainly to the vibrations caused by liquid nitrogen boiling and by vibrations of the box. Further attempts are needed to reduce the magnetic noise inductions. Nevertheless, the estimations promise the maximum signal/noise relation of the high-T(sub c) squid-magnetocardiometer to be not less than 10:1 in a bandwidth of 60 Hz. Apparently, such resolution would be enough not only for steady cardiogram reading but even for thin structure investigation at average technique application.

Polushkin, V. N.↗

NASA NTRS1994

Flexible Heating Head

United States Air Force is investigating method of repairing aircraft by use of adhesive bonding with induction heating to cure adhesive. Fast-acting and reliable induction heating device that is lightweight, portable, and easy to use needed for such applications. Newly developed flexible heating head lightweight and conforms to complex, curved surfaces. Incorporates principles and circuitry of toroid joining gun described in "Toroid Joining Gun for Fittings and Couplings" (LAR-14278). Concentrates heat in local area through induction heating. Flexible heating head contains tank circuit, connected via cable to source of power.

Fox, Robert L.↗

NASA NTRS1993

The efficiency of photovoltaic cells exposed to pulsed laser light

Future space missions may use laser power beaming systems with a free electron laser (FEL) to transmit light to a photovoltaic array receiver. To investigate the efficiency of solar cells with pulsed laser light, several types of GaAs, Si, CuInSe2, and GaSb cells were tested with the simulated pulse format of the induction and radio frequency (RF) FEL. The induction pulse format was simulated with an 800-watt average power copper vapor laser and the RF format with a frequency-doubled mode-locked Nd:YAG laser. Averaged current vs bias voltage measurements for each cell were taken at various optical power levels and the efficiency measured at the maximum power point. Experimental results show that the conversion efficiency for the cells tested is highly dependent on cell minority carrier lifetime, the width and frequency of the pulses, load impedance, and the average incident power. Three main effects were found to decrease the efficiency of solar cells exposed to simulated FEL illumination: cell series resistance, LC 'ringing', and output inductance. Improvements in efficiency were achieved by modifying the frequency response of the cell to match the spectral energy content of the laser pulse with external passive components.

Lowe, R. A.↗

NASA NTRS1993

Advanced electric motor technology flux mapping

Design of electric motors which fulfill the needs of Thrust Vector Control (TVC) actuators used in large rocket propelled launch vehicles is covered. To accomplish this end the methodology of design is laid out in some detail. In addition a point design of a motor to fulfill the requirements of a certain actuator specified by MSFC is accomplished and reported upon. In the course of this design great stress has been placed on ridding the actuator of internally generated heat. To conduct the heat out of the motor use is made of the unique properties of the in house MSFC designed driving electronics. This property is that as along as they are operated in a quasi-linear mode the electronics nullify the effects of armature inductance as far as the phase of the armature current versus the rotor position is concerned. Actually the additional inductance due to the extended end turns in this design is of benefit because in the shorted armature failure mode the armature current in the fault (caused by the rotor flux sweeping past the armature) is diminished at a given rotor speed when compared to a more conventional motor with lower inductance. The magnetic circuit is analyzed using electromagnetic finite element methods.

Doane, George B., III↗

NASA NTRS1993

Forback DC-to-DC converter

A pulse-width modulated DC-to-DC power converter including a first inductor, i.e. a transformer or an equivalent fixed inductor equal to the inductance of the secondary winding of the transformer, coupled across a source of DC input voltage via a transistor switch which is rendered alternately conductive (ON) and nonconductive (OFF) in accordance with a signal from a feedback control circuit is described. A first capacitor capacitively couples one side of the first inductor to a second inductor which is connected to a second capacitor which is coupled to the other side of the first inductor. A circuit load shunts the second capacitor. A semiconductor diode is additionally coupled from a common circuit connection between the first capacitor and the second inductor to the other side of the first inductor. A current sense transformer generating a current feedback signal for the switch control circuit is directly coupled in series with the other side of the first inductor so that the first capacitor, the second inductor and the current sense transformer are connected in series through the first inductor. The inductance values of the first and second inductors, moreover, are made identical. Such a converter topology results in a simultaneous voltsecond balance in the first inductance and ampere-second balance in the current sense transformer.

Lukemire, Alan T.↗

NASA NTRS1994

Charged-particle mutagenesis 2. Mutagenic effects of high energy charged particles in normal human fibroblasts

The biological effects of high Linear Energy Transfer (LET) charged particles are a subject of great concern with regard to the prediction of radiation risk in space. In this report, mutagenic effects of high LET charged particles are quantitatively measured using primary cultures of human skin fibroblasts, and the spectrum of induced mutations are analyzed. The LET of the charged particles ranged from 25 KeV/micrometer to 975 KeV/micrometer with particle energy (on the cells) between 94-603 MeV/u. The X-chromosome linked hypoxanthine guanine phosphoribosyl transferase (hprt) locus was used as the target gene. Exposure to these high LET charged particles resulted in exponential survival curves; whereas, mutation induction was fitted by a linear model. The Relative Biological Effect (RBE) for cell-killing ranged from 3.73 to 1.25, while that for mutant induction ranged from 5.74 to 0.48. Maximum RBE values were obtained at the LET of 150 keV/micrometer. The inactivation cross-section (alpha i) and the action cross-section for mutant induction (alpha m) ranged from 2.2 to 92.0 sq micrometer and 0.09 to 5.56 x 10(exp -3) sq micrometer respectively. The maximum values were obtained by Fe-56 with an LET of 200 keV/micrometer. The mutagenicity (alpha m/alpha i) ranged from 2.05 to 7.99 x 10(exp -5) with the maximum value at 150 keV/micrometer. Furthermore, molecular analysis of mutants induced by charged particles indicates that higher LET beams are more likely to cause larger deletions in the hprt locus.

Chen, D. J.↗

NASA NTRS1995

Forback DC-to-DC converter

Lukemire, Alan T.↗

NASA NTRS1994

DNA-DSB in CHO-K1 cells induced by heavy-ions: Break rejoining and residual damage (GSI)

DNA double strand breaks (DSB's) are the critical lesions involved in cellular effects of ionizing radiation. Therefore, the evaluation of DSB induction in mammalian cells after heavy ion irradiation is an essential task for the assessment of high-LET radiation risk in space. Of particular interest has been the question of how the biological efficiency for the cellular inactivation endpoint relates to the initial lesions (DSBs) at varying LETs. For cell killing, an increased Relative Biological Efficiency (RBE) has been determined for highLET radiation around 100-200 keV/mu m. At higher LET, the RBE's decrease again to values below one for the very heavy particles. At GSI, DSB-induction was measured in CHO-K1 cells following irradiation with accelerated particles covering a wide LET range. The electrophoretic elution of fragmented DNA out of agarose plugs in a constant electrical field was applied for the detection of DSB's. The fraction of DNA retained was determined considering the relative intensities of ethidium bromide fluorescence in the well and in the gel lane. Dose-effect curves were established, from which the RBE for DSB induction was calculated at a fraction of 0.7 of DNA retained In summary, these rejoining studies are in line with an enhanced severity of the DNA DSB's at higher LET's, resulting in a decreased repairability of the induced lesions. However, no information concerning the fidelity of strand breaks rejoining is provided in these studies. To assess correct rejoining of DNA fragments an experimental system involving individual DNA hybridization bands has been set up. In preliminary experiments Sal I generated DNA fragments of 0.9 Mbp were irradiated with xrays and incubated for repair However, restitution of the original signals was not observed, probably due to the high radiation dose necessary for breakage of a fragment of this size. A banding pattern with NotI hybridization signals in a higher MW range (3Mbp) has been obtained by varying the electrophoretic conditions and correct rejoining studies will be further developed in this system.

Taucher-Scholz, G.↗

NASA NTRS1992

Proceedings of the Workshop on Change of Representation and Problem Reformulation

The proceedings of the third Workshop on Change of representation and Problem Reformulation is presented. In contrast to the first two workshops, this workshop was focused on analytic or knowledge-based approaches, as opposed to statistical or empirical approaches called 'constructive induction'. The organizing committee believes that there is a potential for combining analytic and inductive approaches at a future date. However, it became apparent at the previous two workshops that the communities pursuing these different approaches are currently interested in largely non-overlapping issues. The constructive induction community has been holding its own workshops, principally in conjunction with the machine learning conference. While this workshop is more focused on analytic approaches, the organizing committee has made an effort to include more application domains. We have greatly expanded from the origins in the machine learning community. Participants in this workshop come from the full spectrum of AI application domains including planning, qualitative physics, software engineering, knowledge representation, and machine learning.

Lowry, Michael R.↗

NASA NTRS1995

Advanced Propulsion Power Distribution System for Next Generation Electric/Hybrid Vehicle: Preliminary System Studies - Phase 1

The report essentially summarizes the work performed in order to satisfy the above project objective. In the beginning, different energy storage devices, such as battery, flywheel and ultra capacitor are reviewed and compared, establishing the superiority of the battery. Then, the possible power sources, such as IC engine, diesel engine, gas turbine and fuel cell are reviewed and compared, and the superiority of IC engine has been established. Different types of machines for drive motor/engine generator, such as induction machine, PM synchronous machine and switched reluctance machine are compared, and the induction machine is established as the superior candidate. Similar discussion was made for power converters and devices. The Insulated Gate Bipolar Transistor (IGBT) appears to be the most superior device although Mercury Cadmium Telluride (MCT) shows future promise. Different types of candidate distribution systems with the possible combinations of power and energy sources have been discussed and the most viable system consisting of battery, IC engine and induction machine has been identified. Then, HFAC system has been compared with the DC system establishing the superiority of the former. The detailed component sizing calculations of HFAC and DC systems reinforce the superiority of the former. A preliminary control strategy has been developed for the candidate HFAC system. Finally, modeling and simulation study have been made to validate the system performance. The study in the report demonstrates the superiority of HFAC distribution system for next generation electric/hybrid vehicle.

Bose, Bimal K.↗