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NASA NTRS2017

The Integrated Impact of Diet On Human Immune Response, the Gut Microbiota, and Nutritional Status During Adaptation to a Spaceflight Analog

Spaceflight impacts human physiology, including well documented immune system dysregulation. Diet, immune function, and the microbiome are interlinked, but diet is the only one of these factors that we have the ability to easily, and significantly, alter on Earth or during flight. As we understand dietary impacts on physiology more thoroughly, we may then improve the spaceflight diet to improve crew health and potentially reduce flight-associated physiological alterations. It is expected that increasing the consumption of fruits and vegetables and bioactive compounds (e.g.,omega-3 fatty acids, lycopene, flavonoids) and therefore enhancing overall nutritional intake from the nominal shelf-stable, fully-processed space food system could serve as a countermeasure to improve human immunological profiles, the taxonomic profile of the gut microbiota, and nutritional status, especially where currently dysregulated during spaceflight. This interdisciplinary study will determine the effect of the current shelf-stable spaceflight diet compared to an "enhanced" shelf-stable spaceflight diet (25% more foods rich in omega-3 fatty acids, lycopene, flavonoids, fruits, and vegetables). The NASA Human Exploration Research Analog (HERA) 2017 missions, consisting of closed chamber confinement, realistic mission simulation, in a high-fidelity mock space vehicle, will serve as a platform to replicate mission stressors and the dysregulated physiology observed in astronauts. Biosampling of crew members will occur at selected intervals, with complete dietary tracking. Outcome measures will include immune markers (e.g., peripheral leukocyte distribution, inflammatory cytokine profiles, T cell function), the taxonomic and metatranscriptomic profile of the gut microbiome, and nutritional status biomarkers and metabolites. Data collection will also include complete dietary tracking. Statistical evaluations will determine physiological and biochemical shifts in relation to nutrient in take and study phase. Beneficial improvements will provide evidence of the impact of diet on crew health and adaptation to this spaceflight analog, and will aid in the design and development of more-efficient targeted dietary interventions.

Douglas, G. L.↗

NASA NTRS1984

LANDSAT-4 MSS interband registration

Interband registration on raw LANDSAT-4 MSS data was measured in the four MSS bands of the Mistassini, Quebec scene (path-row 16-24, June 21, 1983). Statistical comparison between line-pixel locations of uniformly distributed ground control points in the four different bands permitted quantitative measures of the offset over the entire scene. The statistical distribution of the offset measures permitted evaluation of the standard error on the mean values, giving confidence on their precision. Results obtained using a manual ground control point done on a digital image correction system and those obtained using digital band-to-band correlation adapted from a digital stereographic correlation algorithm are tabulated. The pixel misrepresentation values obtained are compared with published NASA figures.

Grieve, G.↗

NASA NTRS1988

Time domain simulation of the response of geometrically nonlinear panels subjected to random loading

The response of composite panels subjected to random pressure loads large enough to cause geometrically nonlinear responses is studied. A time domain simulation is employed to solve the equations of motion. An adaptive time stepping algorithm is employed to minimize intermittent transients. A modified algorithm for the prediction of response spectral density is presented which predicts smooth spectral peaks for discrete time histories. Results are presented for a number of input pressure levels and damping coefficients. Response distributions are calculated and compared with the analytical solution of the Fokker-Planck equations. RMS response is reported as a function of input pressure level and damping coefficient. Spectral densities are calculated for a number of examples.

Moyer, E. Thomas, Jr.↗

NASA NTRS1993

Piezoelectric actuator models for active sound and vibration control of cylinders

Analytical models for piezoelectric actuators, adapted from flat plate concepts, are developed for noise and vibration control applications associated with vibrating circular cylinders. The loadings applied to the cylinder by the piezoelectric actuators for the bending and in-plane force models are approximated by line moment and line force distributions, respectively, acting on the perimeter of the actuator patch area. Coupling between the cylinder and interior acoustic cavity is examined by studying the modal spectra, particularly for the low-order cylinder modes that couple efficiently with the cavity at low frequencies. Within the scope of this study, the in-plane force model produced a more favorable distribution of low-order modes, necessary for efficient interior noise control, than did the bending model.

Lester, Harold C.↗

NASA NTRS1987

A diagonal implicit multigrid algorithm for the Euler equations

A multigrid implementation of the Alternating Direction Implicit algorithm has been developed to solve the Euler equations of inviscid, compressible flow. The equations are approximated using a finite-volume spatial approximation with added dissipation provided by an adaptive blend of second and fourth differences. For computational efficiency, the equations are diagonalized by a local similariity transformation so that only a decoupled system of scalar pentadiagonal systems need be solved along each line. Results are computed for transonic flows past airfoils and include pressure distributions to verify the accuracy of the basic scheme and convergence histories to demonstrate the efficiency of the method.

Caughey, David A.↗

NASA NTRS2007

Quaternion Averaging

Many applications require an algorithm that averages quaternions in an optimal manner. For example, when combining the quaternion outputs of multiple star trackers having this output capability, it is desirable to properly average the quaternions without recomputing the attitude from the the raw star tracker data. Other applications requiring some sort of optimal quaternion averaging include particle filtering and multiple-model adaptive estimation, where weighted quaternions are used to determine the quaternion estimate. For spacecraft attitude estimation applications, derives an optimal averaging scheme to compute the average of a set of weighted attitude matrices using the singular value decomposition method. Focusing on a 4-dimensional quaternion Gaussian distribution on the unit hypersphere, provides an approach to computing the average quaternion by minimizing a quaternion cost function that is equivalent to the attitude matrix cost function Motivated by and extending its results, this Note derives an algorithm that deterniines an optimal average quaternion from a set of scalar- or matrix-weighted quaternions. Rirthermore, a sufficient condition for the uniqueness of the average quaternion, and the equivalence of the mininiization problem, stated herein, to maximum likelihood estimation, are shown.

Markley, F. Landis↗

NASA NTRS2012

Small Aircraft Data Distribution System

The CARVE Small Aircraft Data Distribution System acquires the aircraft location and attitude data that is required by the various programs running on a distributed network. This system distributes the data it acquires to the data acquisition programs for inclusion in their data files. It uses UDP (User Datagram Protocol) to broadcast data over a LAN (Local Area Network) to any programs that might have a use for the data. The program is easily adaptable to acquire additional data and log that data to disk. The current version also drives displays using precision pitch and roll information to aid the pilot in maintaining a level-level attitude for radar/radiometer mapping beyond the degree available by flying visually or using a standard gyro-driven attitude indicator. The software is designed to acquire an array of data to help the mission manager make real-time decisions as to the effectiveness of the flight. This data is displayed for the mission manager and broadcast to the other experiments on the aircraft for inclusion in their data files. The program also drives real-time precision pitch and roll displays for the pilot and copilot to aid them in maintaining the desired attitude, when required, during data acquisition on mapping lines.

Chazanoff, Seth L.↗

NASA NTRS2019

GEONEX Data Products: Geostationary Satellite Derived Land Surface and Atmospheric Public Data Products

The latest generation of geostationary satellites carry sensors such as the Advanced Baseline Imager (GOES-16/17) and the Advanced Himawari Imager (Himawari-8/9) that closely mimic the spatial and spectral characteristics of MODIS and VIIRS, useful for monitoring land surface conditions. The NASA Earth Exchange (NEX) team at Ames Research Center has embarked on a collaborative effort among scientists from NASA and NOAA exploring the feasibility of producing operational land surface products similar to those from MODIS/VIIRS. The team built a processing pipeline called GEONEX that is capable of converting raw geostationary data into routine products of Fires, surface reflectances, vegetation indices, LAI/FPAR, ET and GPP/NPP using algorithms adapted from both NASA/EOS and NOAA/GOES-R programs. The GEONEX pipeline will begin to produce provisional data products to be consumed by external collaborators and the academic community. In order to better inform and introduce the GEONEX products to the science community, the provisional products shall be distributed from the NAS data portal, located at data.nas.nasa.gov, and simple webpage at www.nasa.gov/geonex has been deployed, which describes any algorithms used in deriving the products, user manuals and data file information. We will also update the status of the data processing, on the website and provide links to the latest datasets, and use a geonex mailing list, using lists.nasa.gov.

Wang, Weile↗

NASA NTRS1989

Decentralized Adaptive Control For Robots

Precise knowledge of dynamics not required. Proposed scheme for control of multijointed robotic manipulator calls for independent control subsystem for each joint, consisting of proportional/integral/derivative feedback controller and position/velocity/acceleration feedforward controller, both with adjustable gains. Independent joint controller compensates for unpredictable effects, gravitation, and dynamic coupling between motions of joints, while forcing joints to track reference trajectories. Scheme amenable to parallel processing in distributed computing system wherein each joint controlled by relatively simple algorithm on dedicated microprocessor.

Seraji, Homayoun↗

NASA NTRS1983

Designing Glass Panels for Economy and Reliability

Analytical method determines probability of failure of rectangular glass plates subjected to uniformly distributed loads such as those from wind, earthquake, snow, and deadweight. Developed as aid in design of protective glass covers for solar-cell arrays and solar collectors, method is also useful in estimating the reliability of large windows in buildings exposed to high winds and is adapted to nonlinear stress analysis of simply supported plates of any elastic material.

Moore, D. M.↗

NASA NTRS1981

Laser velocimeter stand-alone controller

A distributed microprocessor network has been developed to position a laser-based velocity measurement package. Designed primarily for use inside the Ames 40 x 80-foot Subsonic Wind Tunnel, the instrument assembly is remotely operated. The mechanical system is reconfigurable for other test environments which necessitates an adaptive control approach. Three stepper motor drives provide two-dimensional positioning of the sampling point over 200/sq m of the test section, with a 5-mm resolution. Real-time multiprocessing provides fast response, fault detection, and parametric data acquisition. Manual tests are run from a dedicated control panel and automated tests are accomplished via an I.E.E.E 488 interface. The design approach and the progress to date are discussed.

Brown, R.↗

NASA NTRS1990

Parallel simulated annealing algorithms for cell placement on hypercube multiprocessors

Two parallel algorithms for standard cell placement using simulated annealing are developed to run on distributed-memory message-passing hypercube multiprocessors. The cells can be mapped in a two-dimensional area of a chip onto processors in an n-dimensional hypercube in two ways, such that both small and large cell exchange and displacement moves can be applied. The computation of the cost function in parallel among all the processors in the hypercube is described, along with a distributed data structure that needs to be stored in the hypercube to support the parallel cost evaluation. A novel tree broadcasting strategy is used extensively for updating cell locations in the parallel environment. A dynamic parallel annealing schedule estimates the errors due to interacting parallel moves and adapts the rate of synchronization automatically. Two novel approaches in controlling error in parallel algorithms are described: heuristic cell coloring and adaptive sequence control.

Banerjee, Prithviraj↗

NASA NTRS1988

Alpha: A real-time decentralized operating system for mission-oriented system integration and operation

Alpha is a new kind of operating system that is unique in two highly significant ways. First, it is decentralized transparently providing reliable resource management across physically dispersed nodes, so that distributed applications programming can be done largely as though it were centralized. And second, it provides comprehensive, high technology support for real-time system integration and operation, an application area which consists predominately of aperiodic activities having critical time constraints such as deadlines. Alpha is extremely adaptable so that it can be easily optimized for a wide range of problem-specific functionality, performance, and cost. Alpha is the first systems effort of the Archons Project, and the prototype was created at Carnegie-Mellon University directly on modified Sun multiprocessor workstation hardware. It has been demonstrated with a real-time C(sup 2) application. Continuing research is leading to a series of enhanced follow-ons to Alpha; these are portable but initially hosted on Concurrent's MASSCOMP line of multiprocessor products.

Jensen, E. Douglas↗

NASA NTRS1986

An improved multilevel optimization approach for the design of complex engineering systems

Multilevel optimization methods are being considered for the design of complex systems on distributed networks of computers or even parallel processors. An obstacle to the use of multilevel methods is that they can be computationally expensive because of the cycling necessary to account for the coupling between the subproblems. This research effort aims at increasing the efficiency of multilevel optimization by adapting two techniques that are widely used in conventional one-level optimization: constraint approximation and temporary constraint deletion. These improvements are implemented and tested on three-, ten- and 52-bar planar truss designs. The results show that for larger problems (approximately 100 design variables and larger), the cost of analysis dominates the total cost so that multilevel optimization is no more expensive than one-level optimization. If parallel processing is used or the analysis process itself is decomposed, then multilevel optimization stands to become more economical than one-level optimization.

Barthelemy, J.-F. M.↗

NASA NTRS1991

Contraction ratio effects in a generic sidewall compression scramjet inlet - A computational and experimental investigation

Computed and experimental data on a generic three-dimensional sidewall compression scramjet inlet with a leading edge sweep of 45 degrees at Mach 20 are presented. A three-dimensional Navier-Stokes code was adapted to perform preliminary parametric studies leading to the present configuration. Following the design phase, the code was then employed as an analysis tool to provide a better understanding of the flow field and the experimental static and pitot pressure data. The model possessed 240 static pressure orifices distributed on the forebody plane, sidewalls, and cowl and was tested in the 31 Inch Mach 10 facility at the NASA Langley Research Center. Pitot rakes were employed to map the entrance and exit planes. The contraction ratio was observed to have a dominant effect on the inlet shock structure and performance; these effects are the emphasis of the present report. In addition to pressure measurements, oil flows were used for further visualization and comparison with computation.

Holland, Scott D.↗

NASA NTRS2006

Spread and SpreadRecorder An Architecture for Data Distribution

The Space Acceleration Measurement System (SAMS) project at the NASA Glenn Research Center (GRC) has been measuring the microgravity environment of the space shuttle, the International Space Station, MIR, sounding rockets, drop towers, and aircraft since 1991. The Principle Investigator Microgravity Services (PIMS) project at NASA GRC has been collecting, analyzing, reducing, and disseminating over 3 terabytes of collected SAMS and other microgravity sensor data to scientists so they can understand the disturbances that affect their microgravity science experiments. The years of experience with space flight data generation, telemetry, operations, analysis, and distribution give the SAMS/ PIMS team a unique perspective on space data systems. In 2005, the SAMS/PIMS team was asked to look into generalizing their data system and combining it with the nascent medical instrumentation data systems being proposed for ISS and beyond, specifically the Medical Computer Interface Adapter (MCIA) project. The SpreadRecorder software is a prototype system developed by SAMS/PIMS to explore ways of meeting the needs of both the medical and microgravity measurement communities. It is hoped that the system is general enough to be used for many other purposes.

Wright, Ted↗

NASA NTRS2012

Spatially Resolved Temperature and Water Vapor Concentration Distributions in Supersonic Combustion Facilities by TDLAT

Detailed knowledge of the internal structure of high-enthalpy flows can provide valuable insight to the performance of scramjet combustors. Tunable Diode Laser Absorption Spectroscopy (TDLAS) is often employed to measure temperature and species concentration. However, TDLAS is a path-integrated line-of-sight (LOS) measurement, and thus does not produce spatially resolved distributions. Tunable Diode Laser Absorption Tomography (TDLAT) is a non-intrusive measurement technique for determining two-dimensional spatially resolved distributions of temperature and species concentration in high enthalpy flows. TDLAT combines TDLAS with tomographic image reconstruction. More than 2500 separate line-of-sight TDLAS measurements are analyzed in order to produce highly resolved temperature and species concentration distributions. Measurements have been collected at the University of Virginia's Supersonic Combustion Facility (UVaSCF) as well as at the NASA Langley Direct-Connect Supersonic Combustion Test Facility (DCSCTF). Due to the UVaSCF s unique electrical heating and ability for vitiate addition, measurements collected at the UVaSCF are presented as a calibration of the technique. Measurements collected at the DCSCTF required significant modifications to system hardware and software designs due to its larger measurement area and shorter test duration. Tomographic temperature and water vapor concentration distributions are presented from experimentation on the UVaSCF operating at a high temperature non-reacting case for water vitiation level of 12%. Initial LOS measurements from the NASA Langley DCSCTF operating at an equivalence ratio of 0.5 are also presented. Results show the capability of TDLAT to adapt to several experimental setups and test parameters.

Busa, K. M.↗

NASA NTRS2024

Transfer-AE: A novel autoencoder-based impact detection model for structural digital twin

Accurately detecting the location and intensity of impacts is crucial for ensuring structural safety. Currently, AI-based structural impact detection methods are widely used for their excellent detection accuracy. However, their generalization capability is limited by the scenarios present in the training data. Many complex and dangerous impact scenarios are difficult to conduct real-world experiments on to collect sufficient samples. To capture all impact scenarios and fully leverage the advantages of AI-based detection technologies, advanced methods involve combining real-world structural monitoring data with corresponding numerical models to construct digital twins. These methods continuously refine the created numerical models with limited real-world data and provide diverse impact scenarios through numerical model simulations. However, there are inevitable differences between digital models and physical models that are challenging to correct through mechanical means. This discrepancy in data distribution between the two models significantly hinders the application of digital twin technology in impact/event identification tasks. To address this challenge, this study proposes a novel model based on autoencoders, named Transfer-AE. Transfer-AE encodes the common features of digital twins in the latent space to bridge the uncertainty gap at a macro scale between numerical models and physical models and synchronously fits the magnitude and location of the impact load in the decoder. This enables consistent detection results for the same impact event, whether the sample comes from the numerical model or the physical model. Transfer-AE includes two operating modes: Mode 1 has a fixed computational complexity with stable inference speed, but the training cost and difficulty increase with data distribution. Mode 2's computational complexity increases with data distribution, but it has a fixed training cost and speed. In both cases involving the geodesic dome structure simulating a deep space habitat and the IASC-ASCE benchmark structure, Transfer-AE demonstrated the best performance in impact localization and quantification tasks compared to mainstream domain-adaptive transfer models.

Chengjia Han↗