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At least 667 records · Page 37

A comparison of quality factors and weighting factors for characterizing astronaut radiation exposures

Radiation exposures are typically characterized by two quantities. The first is the absorbed dose, or the energy deposited per unit mass for specific types of radiation passing through specified materials. The same amount of energy deposited in material by two different types of radiation, however, can result in two different levels of risk. Because of this, for the purpose of radiation protection operations, absorbed dose is modified by a second factor intended to normalize the risk associated with a given exposure. We present here an inter-comparison of methods for this modification. First is the radiation quality factor (Q), as defined by ICRP publication 60. This quantity is related functionally to the unrestricted linear energy transfer (LET) of a given radiation, and is multiplied by the absorbed dose to derive the dose equivalent (H). The second method for modifying absorbed dose is the radiation weighting factor, also given in ICRP-60, or as modified in NCRP report 115. To implement the weighting factor, the absorbed dose resulting from incidence of a particular radiation is multiplied by a factor assigned to that type of radiation, giving the equivalent dose. We compare calculations done based on identical fields of radiation representative of that encountered by the MIR space station, applying each of these two methods. c2002 COSPAR. Published by Elsevier Science Ltd. All rights reserved.

NASA Center JSC↗

Integrating Human Factors in Dynamic Rideshare Assignment: Willingness-To-Pay for Delay

Dynamic ride-sharing (DRS) has been projected to be a key solution to lowering system-wide congestion. Despite recent developmental progress, demand studies for DRS suggest low levels of willingness for travelers to use such services. The disconnect between DRS system designs and user preferences limits the application impacts of DRS in the real world. Therefore, this paper aims to design a new DRS trip/vehicle assignment strategy by considering the user preferences of choices under different levels of service. In this study, an agent-based simulation approach is used to model a fleet of shared vehicles that allows DRS. An optimization model is developed to match riders to vehicles while accounting for traveler delay and delay acceptance. Travelers are also dynamically issued predictive discounts, catered to their expected willingness to pay, to incentivize them to accept longer trip delays. Results show that the proposed approach can improve system efficiency by increasing average vehicle occupancy by up to 1.0 persons/trip and DRS acceptance by up to 38.9% depending on fleet size. Additionally, congestion is eased through the decrease of empty vehicle miles traveled by up to 7.1%.

Paul, Joseph↗

Experimental test of model predictive control in a variable air volume system

Model predictive control (MPC) has been widely studied as a promising approach for improving energy efficiency and operational flexibility in buildings, yet its real-world performance for commercial variable air volume (VAV) systems remains insufficiently characterized. In particular, the impacts of model mismatch on control robustness, real-time computational burden, and device-level operation are rarely evaluated using long-term field data. Here, this study presents a comprehensive experimental evaluation of MPC applied to a full-scale VAV system in Oak Ridge National Laboratory’s Flexible Research Platform-2 building with constant cooling/heating temperature setpoints and no occupancy. The study offers three key advantages over existing work: (1) it uses a representative building in a full-scale experimental test, capturing realistic system dynamics and complexity; (2) it evaluates a relatively sophisticated MPC formulation using two different optimization solvers (Gurobi and PSO), fully accounting for computational complexity and methodological diversity; and (3) it systematically assesses potential negative impacts on various building devices, benchmark against a well-established baseline, ASHRAE Guideline 36 (G36). To isolate zone- and air-handling-unit–level supervisory control effects, the supply fan was operated with a fixed static pressure setpoint under all strategies, and the trim-and-response static pressure reset in G36 was not enabled. Results show that MPC maintained thermal comfort while improving energy efficiency. Abrupt solar radiation variations degraded performance. Computation times ranged from ∼1 s (Gurobi) to ∼ 70 s (PSO). Compared with G36, MPC achieves 33% energy savings and reduces median reheat coil output by approximately a factor of 5–10 for a representative cooling day under matched weather conditions. However, it increases the maximum discomfort deviation from 0.5 to 1°C and results in a 32% increase in staging frequency. In addition, PSO-based MPC introduced damper oscillations, also affecting actuator longevity.

ASHRAE guideline 36↗

On the Ordering Mechanism of Cu + in 2D van der Waals Multiferroic CuCrP 2 S 6

CuCrP 2 S 6 is a van der Waals multiferroic where the tunable Cu + sublattice underpins its exceptional ferroelectric and electronic switching properties. Yet, the microscopic mechanism governing Cu + ordering has remained elusive. Here, we combine single-crystal X-ray and neutron diffraction with pair distribution function analysis to uncover a temperature-driven evolution of Cu + ordering, giving rise to an incommensurate quasi-antipolar phase between the paraelectric and antiferroelectric states. The modulation originates from correlated Cu + occupancy redistribution coupled to breathing distortion of surrounding S 3 triangles, establishing a symmetry-adapted lattice distortion mode. Diffuse scattering persisting over 35 K above the transition confirms that the structural instability follows an order-disorder mechanism. The spontaneous off-centering of Cu + positions CuCrP 2 S 6 as a model platform for correlated order-disorder phenomena in 2D layered ferroics, and provides design principles for next-generation memory and logic devices.

ferroelectrics↗

Bosonic field digitization for quantum computers

Quantum simulation of quantum field theory is a flagship application of quantum computers that promises to deliver capabilities beyond classical computing. The realization of quantum advantage will require methods that can accurately predict error scaling as a function of the resolution and parameters of the model and that can be implemented efficiently on quantum hardware. In this paper, we address the representation of lattice bosonic fields in a discretized field amplitude basis, develop methods to predict error scaling, and present efficient qubit implementation strategies. A low-energy subspace of the bosonic Hilbert space, defined by a boson occupation number cutoff, can be represented with exponentially good accuracy by a low-energy subspace of a finite-size Hilbert space. The finite representation construction and the associated errors are directly related to the accuracy of the Nyquist-Shannon sampling and the finite Fourier transforms of the boson number states in the field and the conjugate-field bases. We analyze the relation between the boson mass, the discretization parameters used for wave function sampling, and the finite representation size. Numerical simulations of small size Φ 4 problems demonstrate that the boson mass optimizing the sampling of the ground state wave function is a good approximation to the optimal boson mass yielding the minimum low-energy subspace size. However, we find that accurate sampling of general wave functions does not necessarily result in accurate representation. Finally, we develop methods for validating and adjusting the discretization parameters to achieve more accurate simulations.

72 PHYSICS OF ELEMENTARY PARTICLES AND FIELDS↗

Smart Ventilation for Advanced California Homes

This project investigated smart ventilation approaches to minimize energy use for providing indoor air quality (IAQ) in high performance new California homes. Evaluation criteria included annual ventilation-related energy, peak energy and time-of-use savings, and the indoor air quality relative to a minimally code-compliant ventilation system. The simulations used CONTAM’s air flow and contaminant transport model, combined with the EnergyPlus building loads model. House types representing the default California Energy Code compliance homes were investigated for four California climate zones, covering a wide range of climate types. Both single and multi-zone smart ventilation controls were investigated. Contaminant sources included contaminants emitted continuously and varying with time, temperature and relative humidity, episodic emissions from occupant activities and outdoor particles. Single-zone ventilation controls that varied ventilation depending on outdoor temperatures were able to consistently save half of ventilation-related energy without compromising long-term IAQ. Ventilation strategies that tracked occupancy were less successful, because this work included generic contaminants with constant background emission rates. Energy performance for occupancy controls improved with a one-hour pre-occupancy flush out strategy. The addition of zoning ventilation controls did not offer significant IAQ to energy improvements compared to non-zonal versions of the same ventilation system type. The best controls had HVAC energy savings of 10-20%, with individual cases reaching up to 40% savings. However, these savings cannot be achieved without worsening personal exposures for at least one contaminant. A metric is needed to assess the competing changes in exposure to different contaminants in order to determine the net-health impacts of a control strategy. Controls that directly sensed contaminants and controlled them to acceptable levels showed that the California OEHHA limit for formaldehyde completely dominates system performance, with homes not able to meet the limit even with continuous operation of a fan sized to twice the current code minimum.

32 ENERGY CONSERVATION, CONSUMPTION, AND UTILIZATI↗

Lunar Station: The Next Logical Step in Space Development

The International Space Station (ISS) is the product of the efforts of sixteen nations over the course of several decades. It is now complete, operational, and has been continuously occupied since November of 20001. Since then the ISS has been carrying out a wide variety of research and technology development experiments, and starting to produce some pleasantly startling results. The ISS has a mass of 420 metric tons, supports a crew of six with a yearly resupply requirement of around 30 metric tons, within a pressurized volume of 916 cubic meters, and a habitable volume of 388 cubic meters. Its solar arrays produce up to 84 kilowatts of power. In the course of developing the ISS, many lessons were learned and much valuable expertise was gained. Where do we go from here? The ISS offers an existence proof of the feasibility of sustained human occupation and operations in space over decades. It also demonstrates the ability of many countries to work collaboratively on a very complex and expensive project in space over an extended period of time to achieve a common goal. By harvesting best practices and lessons learned, the ISS can also serve as a useful model for exploring architectures for beyond low-­‐ earth-­‐orbit (LEO) space development. This paper will explore the concept and feasibility for a Lunar Station. The Station concept can be implemented by either putting the equivalent capability of the ISS down on the surface of the Moon, or by developing the required capabilities through a combination of delivered materials and equipment and in situ resource utilization (ISRU). Scenarios that leverage existing technologies and capabilities as well as capabilities that are under development and are expected to be available within the next 3-­5 years, will be examined. This paper will explore how best practices and expertise gained from developing and operating the ISS and other relevant programs can be applied to effectively developing Lunar Station.

Lunar↗

Deep Space Storm Shelter Simulation Study

Missions outside of Earth's magnetic field are impeded by the presence of radiation from galactic cosmic rays and solar particle events. To overcome this issue, NASA's Advanced Exploration Systems Radiation Works Storm Shelter (RadWorks) has been studying different radiation protective habitats to shield against the onset of solar particle event radiation. These habitats have the capability of protecting occupants by utilizing available materials such as food, water, brine, human waste, trash, and non-consumables to build short-term shelters. Protection comes from building a barrier with the materials that dampens the impact of the radiation on astronauts. The goal of this study is to develop a discrete event simulation, modeling a solar particle event and the building of a protective shelter. The main hallway location within a larger habitat similar to the International Space Station (ISS) is analyzed. The outputs from this model are: 1) the total area covered on the shelter by the different materials, 2) the amount of radiation the crew members receive, and 3) the amount of time for setting up the habitat during specific points in a mission given an event occurs.

Dugan, Kathryn↗

NASA Occupant Protection Standards Development

Historically, spacecraft landing systems have been tested with human volunteers, because analytical methods for estimating injury risk were insufficient. These tests were conducted with flight-like suits and seats to verify the safety of the landing systems. Currently, NASA uses the Brinkley Dynamic Response Index to estimate injury risk, although applying it to the NASA environment has drawbacks: (1) Does not indicate severity or anatomical location of injury (2) Unclear if model applies to NASA applications. Because of these limitations, a new validated, analytical approach was desired. Leveraging off of the current state of the art in automotive safety and racing, a new approach was developed. The approach has several aspects: (1) Define the acceptable level of injury risk by injury severity (2) Determine the appropriate human surrogate for testing and modeling (3) Mine existing human injury data to determine appropriate Injury Assessment Reference Values (IARV). (4) Rigorously Validate the IARVs with sub-injurious human testing (5) Use validated IARVs to update standards and vehicle requirement

Somers, Jeffrey↗

Effect of crash pulse shape on seat stroke requirements for limiting loads on occupants of aircraft

An analytical study was made to provide comparative information on various crash pulse shapes that potentially could be used to test seats under conditions included in Federal Regulations Part 23 Paragraph 23.562(b)(1) for dynamic testing of general aviation seats, show the effects that crash pulse shape can have on the seat stroke requirements necessary to maintain a specified limit loading on the seat/occupant during crash pulse loadings, compare results from certain analytical model pulses with approximations of actual crash pulses, and compare analytical seat results with experimental airplace crash data. Structural and seat/occupant displacement equations in terms of the maximum deceleration, velocity change, limit seat pan load, and pulse time for five potentially useful pulse shapes were derived; from these, analytical seat stroke data were obtained for conditions as specified in Federal Regulations Part 23 Paragraph 23.562(b)(1) for dynamic testing of general aviation seats.

Carden, Huey D.↗

A hardware-in-the-loop (HIL) testbed for cyber-physical energy systems in smart commercial buildings

In recent years, there has been a growing trend toward the development of smart buildings that rely on cyber-physical systems (CPS) to optimize occupant comfort, safety, and energy efficiency. To ensure the reliable and efficient operation of CPS with designed control strategies, it is important to evaluate their performance under various scenarios before deploying them in the real world. This is where a Hardware-in-the-loop (HIL) testbed designed for studying sensor and control-related studies in smart buildings can be highly valuable. With the growing threat of cyber-attacks and physical faults targeting smart buildings, it is essential to ensure the security of building operations. A HIL testbed can emulate cyber-attack and physical fault scenarios, allowing researchers to develop and test threat detection and mitigation algorithms. This enables researchers to identify potential issues and optimize the algorithms in a safe and controlled environment before they are deployed in real-world settings, reducing the risk of failures that can negatively impact occupant comfort, safety, and energy efficiency. Therefore, this paper developed a HIL testbed designed for cyber-physical energy systems (e.g. buildings automation system (BAS)) in smart commercial buildings. The HIL testbed is comprised of a real-time building and Heating, Ventilation, and Air-Conditioning (HVAC) emulator using Modelica-based dynamic models, a set of BAS controllers, and a BAS computer server. The data generation capability of the HIL testbed is demonstrated by tracking normal and faulty operating data in the BAS, as well as monitoring detailed network traffic in the local BAS network. Here, this study further demonstrates the HIL testbed’s capability by conducting case studies on real-time physical fault and cyber-attack experiments using a Department of Energy (DOE) prototype commercial building. It is anticipated that the fully functional HIL testbed will be utilized for a variety of sensor and control-related studies, including but not limited to testing, developing, validating of different HVAC control strategies, fault detection & diagnosis, energy monitoring and analysis, cyber security study, etc.

32 ENERGY CONSERVATION, CONSUMPTION, AND UTILIZATI↗

Finite Element Analysis of an Energy Absorbing Sub-floor Structure

As part of the Advanced General Aviation Transportation Experiments program, the National Aeronautics and Space Administration's Langley Research Center is conducting tests to design energy absorbing structures to improve occupant survivability in aircraft crashes. An effort is currently underway to design an Energy Absorbing (EA) sub-floor structure which will reduce occupant loads in an aircraft crash. However, a recent drop test of a fuselage specimen with a proposed EA sub-floor structure demonstrated that the effects of sectioning the fuselage on both the fuselage section's stiffness and the performance of the EA structure were not fully understood. Therefore, attempts are underway to model the proposed sub-floor structure on computers using the DYCAST finite element code to provide a better understanding of the structure's behavior in testing, and in an actual crash.

Moore, Scott C.↗

Intricate Crystal Structure of Dihydrolipoamide Dehydrogenase (E3) with its Binding Protein: Multiple Copies, Dynamic and Static Disorders

Human E3 and binding protein E3BP are two components of the pyruvate dehydrogenase complex. Crystallization of E3 with 221-amino acid fragment of E3BP (E3BPdd) led to crystals that diffracted to a resolution of 2.6 Angstroms. Structure determination involved molecular replacement using a dimer of E3 homolog as a search model and de novo building of the E3BPdd peptide. Solution was achieved by inclusion of one E3 dimer at a time, followed by refinement until five E3 dimers were located. This complete content of E3 provided electron density maps suitable for tracing nine peptide chains of E3BPdd, eight of them being identified with partial occupancies. Final content of the asymmetric unit consists of five E3 dimers, each binding one E3BPdd molecule. In four of these molecular complexes, E3BPdd is in static disorder resulting in E3BPdd binding to either one or the other monomer of the E3 dimer. However, E3BPdd of the fifth E3 dimer forms specific contacts that lock it at one monomer. In addition to this static disorder, E3BPdd reveals high mobility in the limited space of the crystal lattice. Support from NIH and NASA.

Makal, A.↗

The Evaluation of a Test Device for Human Occupant Restraint (THOR) Under Vertical Loading Conditions: Part 1 - Experimental Setup and Results

A series of 16 vertical tests were conducted on a Test Device for Human Occupant Restraint (THOR) - NT 50th percentile Anthropomorphic Test Device (ATD) at NASA Langley Research Center (LaRC). The purpose of the tests conducted at NASA LaRC was threefold. The first was to add vertical response data to the growing test database for THOR-NT development and validation. Second, the THOR-NT analytical computational models currently in development must be validated for the vertical loading environment. The computational models have been calibrated for frontal crash environments with concentration on accurately replicating head/neck, thoracic, and lower extremity responses. Finally, familiarity with the THOR ATD is necessary because NASA is interested in evaluating advanced ATDs for use in future flight and research projects. The THOR was subjected to vertical loading conditions ranging between 5 and 16 g in magnitude and 40 to 120 milliseconds (msec) in duration. It was also tested under conditions identical to previous tests conducted on the Hybrid II and III ATDs to allow comparisons to be made. Variations in the test setup were also introduced, such as the addition of a footrest in an attempt to offload some of the impact load into the legs. A full data set of the THOR-NT ATD will be presented and discussed. Results from the tests show that the THOR was largely insensitive to differences in the loading conditions, perhaps due in part to their small magnitudes. THOR responses, when compared to the Hybrid II and III in the lumbar region, demonstrated that the THOR more closely resembled the straight spine Hybrid setup. In the neck region, the THOR behaved more like the Hybrid III. However in both cases, the responses were not identical, indicating that the THOR would show differences in response than the Hybrid II and III ATDs when subjected to identical impact conditions. The addition of a footrest did not significantly affect the THOR response due to the nature of how the loading conditions were applied.

Littell, Justin D.↗

Simulation of Lift plus Cruise Vehicle Models to Define a Full-Scale Crash Test Campaign

A series of dynamic simulations were completed on the National Aeronautics and Space Administration(NASA) Lift plus Cruise (LPC) concept electric Vertical Take-off and Landing (eVTOL) vehicle in preparation for an anticipated future full-scale crash-test campaign. The crash test campaign is envisioned as a data gathering exercise with an intent generating full-scale test data to inform eVTOL crashworthiness regulations, evaluate the use of energy absorbing concepts within vehicle design, and validate finite element modeling techniques used in crashworthiness predictions. This report discusses the two main objectives for the simulation efforts: the development of a structural cabin section, and a series of analyses utilized to determine the sensitivities of impact variables. A structural cabin section was created based from previous research efforts involving the LPC vehicle utilized for occupant response. To refine for the structural modifications, the wing and tail sections of the vehicle were removed. The tail was replaced with a representative mass at the aft of the fuselage. The overhead wing was replaced with a beam structure sized to approximate the bending response of the wing under crash loading conditions. The beam structure was fixed to the fuselage similar to the original Wingbox design in order to properly capture effects of this overhead mass on survivable volume within the vehicle. The fidelity of the fuselage frame structure within the FEM was increased to quantify the effect of frame sizing on structural response. From this an eVTOL test article design was developed, which satisfied basic crashworthiness requirements, was reconfigurable to assess the effect of various design avenues on structural response and optimized to improve manufacturability. The impact variable sensitivity results primarily show the orientation of the impact vector played a major role in types of injuries sustained, along with their severity. The vehicle was largely insensitive to small variations in pitch attitude but highly sensitive to both impact surface at certain angles and landing gear location.

eVTOL↗

Using FLAC{sup R} Modeling Software to Analyze the Stability of a LLRW Disposal Facility - 20031

Waste Control Specialists (WCS) wished to amend its existing LLRW disposal license such that it might use gravel aggregate instead of concrete as backfill around large component (LC) parts from decommissioned nuclear reactors. A classical mechanics evaluation of the strength of the LCs was presented to the Texas Commission on Environmental Quality (TCEQ), demonstrating that the LCs had adequate capacity to withstand the loads within the facilities, and that concrete was unnecessary for structural support. TCEQ requested that additional analyses of the LCs within the facilities be performed using FLAC{sup R} finite difference modeling software. Because FLAC{sup R} has the capability of modeling the support provided by the lateral earth pressures, the factors of safety against failure for the LCs increased. TCEQ found the FLAC{sup R} analyses presented in this report to be satisfactory, and granted WCS' license amendment request. This work demonstrates that FLAC{sup R} may be used advantageously to more accurately represent the complexities of the physical situation being modeled. (authors)

12 MANAGEMENT OF RADIOACTIVE AND NON-RADIOACTIVE W↗

Comprehensive characterization of N- and O- glycosylation of SARS-CoV-2 human receptor angiotensin converting enzyme 2

The emergence of the coronavirus disease 2019 (COVID-19) pandemic caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has created the need for development of new therapeutic strategies. Understanding the mode of viral attachment, entry and replication has become a key aspect of such interventions. The coronavirus surface features a trimeric spike (S) protein that is essential for viral attachment, entry and membrane fusion. The S protein of SARS-CoV-2 binds to human angiotensin converting enzyme 2 (hACE2) for entry. Herein, we describe glycomic and glycoproteomic analysis of hACE2 expressed in HEK293 cells. We observed high glycan occupancy (73.2 to 100%) at all seven possible N-glycosylation sites and surprisingly detected one novel O-glycosylation site. To deduce the detailed structure of glycan epitopes on hACE2 that may be involved in viral binding, we have characterized the terminal sialic acid linkages, the presence of bisecting GlcNAc and the pattern of N-glycan fucosylation. We have conducted extensive manual interpretation of each glycopeptide and glycan spectrum, in addition to using bioinformatics tools to validate the hACE2 glycosylation. Our elucidation of the site-specific glycosylation and its terminal orientations on the hACE2 receptor, along with the modeling of hACE2 glycosylation sites can aid in understanding the intriguing virus-receptor interactions and assist in the development of novel therapeutics to prevent viral entry. Here, the relevance of studying the role of ACE2 is further increased due to some recent reports about the varying ACE2 dependent complications with regard to age, sex, race and pre-existing conditions of COVID-19 patients.

59 BASIC BIOLOGICAL SCIENCES↗

Household energy resilience in extreme weather events: An investigation of energy service importance, HVAC usage behaviors, and willingness to pay

Household energy resilience, particularly maintaining essential energy services within an acceptable and affordable level, is critical during extreme weather events (e.g., winter storms, heat waves) with power shortages or outages. However, the research on the importance and acceptable compromise levels of energy services, HVAC usage behavior changes, and willingness to pay (WTP) for energy services during disasters is limited. Therefore, this study investigates the importance and compromise of household energy services, HVAC usage behaviors, and WTP, as three key dimensions of household energy resilience, in both normal days and disaster scenarios through surveys (n=485). First, 12 common residential end-uses are grouped into high, mid, and low-priority services using hierarchical clustering, in which high-priority services (perceived as important and un-compromisable) include food cooking and storage (refrigerator and freezer) and thermal comfort (space heating and cooling), mid-priority services involve water heating and lighting, while low-priority services are mostly related to entertainment and housework (e.g., TV, laundry). Also, HVAC use patterns demonstrate that occupants become more energy conservative during disasters, e.g., reducing durations of running HVAC and adjusting temperature setpoints to save energy. In terms of energy cost, approximately 60% of respondents are willing to pay more to maintain energy services during disasters, although only 13% are prepared to pay over double the normal energy prices. The regression models further reveal that household energy resilience varies across different sociodemographic groups (e.g., age, income, family size) and is impacted by disaster experience and beliefs in clean energy and climate. In conclusion, these research findings provide important perspectives to understand household energy resilience and inform measures for disaster adaptation of households in extreme weather events.

32 ENERGY CONSERVATION, CONSUMPTION, AND UTILIZATI↗