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At least 667 records · Page 37

Enhanced detection of paramagnetic fluorine-19 magnetic resonance imaging agents using zero echo time sequence and compressed sensing

Fluorine-19 ( 19 F) magnetic resonance imaging (MRI) is an emerging technique offering specific detection of labeled cells in vivo. Lengthy acquisition times and modest signal-to-noise ratio (SNR) makes three-dimensional spin-density–weighted 19 F imaging challenging. Recent advances in tracer paramagnetic metallo-perfluorocarbon (MPFC) nanoemulsion probes have shown multifold SNR improvements due to an accelerated 19 F T 1 relaxation rate and a commensurate gain in imaging speed and averages. However, 19 F T 2 -reduction and increased linewidth limit the amount of metal additive in MPFC probes, thus constraining the ultimate SNR. To overcome these barriers, we describe a compressed sampling (CS) scheme, implemented using a “zero” echo time (ZTE) sequence, with data reconstructed via a sparsity-promoting algorithm. Our CS-ZTE scheme acquires k-space data using an undersampled spherical radial pattern and signal averaging. Image reconstruction employs off-the-shelf sparse solvers to solve a joint total variation and -norm regularized least square problem. To evaluate CS-ZTE, we performed simulations and acquired 19 F MRI data at 11.7 T in phantoms and mice receiving MPFC-labeled dendritic cells. For MPFC-labeled cells in vivo, we show SNR gains of ~6.3 × with 8-fold undersampling. We show that this enhancement is due to three mechanisms including undersampling and commensurate increase in signal averaging in a fixed scan time, denoising attributes from the CS algorithm, and paramagnetic reduction of T 1 . Importantly, 19 F image intensity analyses yield accurate estimates of absolute quantification of 19 F spins. Overall, the CS-ZTE method using MPFC probes achieves ultrafast imaging, a substantial boost in detection sensitivity, accurate 19 F spin quantification, and minimal image artifacts.

46 INSTRUMENTATION RELATED TO NUCLEAR SCIENCE AND ↗

Nuclear Data Sheets for A=245

Available information pertaining to the nuclear structure of ground and excited states for all known nuclei with mass numbers A=245 have been compiled and evaluated. In this work, the adopted level and decay schemes, as well as the detailed nuclear properties and configuration assignments based on experimental data, are presented for these nuclides. When there are insufficient data, expected values from systematics of nuclear properties and/or theoretical calculations are utilized. Unexpected or discrepant experimental results are also noted. Since the last evaluation, new rotational bands in 245 Pu have been observed to high spin from transfer reaction 244 Pu( 209 Bi, 208 Biγ) by 2014Ho16. While in 245 Am, the 249 Bk α decay measurements by 2013Ah03 added a new rotational band based on π3/2[521] configuration. The 245 Pu β - decay scheme is basically what was proposed in the late 60's and 47 γ rays have still not been placed. In 245 Cm, precise alpha energies and intensities were measured by 2015Ah03 in 249Cf α decay. Their reported alpha energies of the main α group were about 2 keV lower than in the previous evaluation. The spin and parity of the g.s. of 245 Es is still ambiguous as more detailed information on the decay is needed. With the production of 249 No via fusion evaporation reaction by groups in Dubna and GSI, it's alpha decay was studied and some properties of the daughter 245 Fm were published and included in this evalaution. Information on the other nuclides is scarce and not much has been investigated since the last evaluation. A summary and compilation of the discovery of the various nuclides in this mass region is given in: 2013Fr02 ( 245 Pu, 245 Am, 245 Cm, 245 Bk, 245 Cf), 2011Me01 ( 245 Es), and 2013Th02 ( 245 Md, 245 Fm).

73 NUCLEAR PHYSICS AND RADIATION PHYSICS↗

Charge Correlations in Cuprate Superconductors

High-temperature superconductivity, with transition temperatures up to ≈134 K at ambient pressure, occurs in layered cuprate compounds. The conducting CuO 2 planes, which are universally present, are responsible for the superconductivity but also show a disposition to other competing states including spin and charge order. Charge-density-wave (CDW) order appears to be a universal property of cuprate superconductors. It has been studied via a multitude of probes including X-ray and neutron scattering, nuclear magnetic resonance, scanning probe techniques, electronic transport, and quantum oscillations. Here, we review the microscopic properties of the CDW order. We discuss the nature of the ordered state, that is, its symmetry and microscopic structure. Furthermore, we show how the CDW order is related to quenched disorder, host structure, symmetry breaking perturbations, and magnetic fields. Here, we also describe measurements of dynamic collective charge excitations that are closely related to the quasi-static CDW order. Finally, we highlight some of the debated issues in the field, including the origin of the CDW order, the relationship to spin order, and the nature of the spatial CDW correlations.

75 CONDENSED MATTER PHYSICS, SUPERCONDUCTIVITY AND↗

Proton-detected 15 N- 1 H dipolar coupling/ 1 H chemical shift correlation experiment for the measurement of NH distances in biological solids under fast MAS solid-state NMR

Measurement of distances from dipolar couplings is essential for structural characterization, refinement and validation using the solid-state nuclear magnetic resonance (ssNMR) spectroscopy. Particularly, knowledge about NH dipolar interactions in biological solids is important for understanding the hydrogen (H)-bonding interactions, molecular geometry and spin dynamics. In this regard, we have proposed a proton-detected two-dimensional (2D) 15 N- 1 H dipolar coupling/ 1 H chemical shift correlation experiment using the C-symmetry based windowless recoupling of chemical shift anisotropy (ROCSA) in combination with the DIPSHIFT pulse-based method for the measurement of short NH distances in the isotopically labeled and naturally abundant biological solids at fast magic angle spinning (MAS) rates (40–70 kHz). Our proposed method results in undistorted recoupled 15 N- 1 H dipolar coupling powder lineshapes that are free from the recoupled 1 H CSA contributions under the 15 N evolution, a feature that is essential for the measurement of NH distances with improved accuracy (± 500 Hz in terms of the NH dipolar couplings). The pulse sequence developed in the present study is also insensitive to the 1H–1H homonuclear dipolar interactions, relaxation effects owing to its constant-time implementation, and t1-noise from the fluctuations in the MAS.

72 PHYSICS OF ELEMENTARY PARTICLES AND FIELDS↗

How EIC can help us to understand heavy-ion collisions

In this work, I give a brief overview of the science cases of the Electron-Ion Collider (EIC) with a particular emphasis on the connections to the physics of ultrarelativistic heavy-ion collisions.

73 NUCLEAR PHYSICS AND RADIATION PHYSICS↗

Transverse Λ polarization in e + e - collisions

In this paper we study transverse polarization of hyperons in single-inclusive leptonic annihilation. We show that when the transverse momentum of the baryon is measured with respect to the thrust axis, a transverse momentum dependent (TMD) factorization formalism is required and the polarization is generated by the TMD polarizing fragmentation function (TMD PFF), D 1 T ⊥ . However, when the transverse momentum of the baryon is measured with respect to the momentum of the initial leptons, a collinear twist-3 formalism is required and the polarization is generated by the intrinsic collinear twist-3 fragmentation function D T . Thus while these measurements differ from one another only by a change in the measurement axis, they probe different distribution functions. Recently, Belle measured a significant polarization in single-inclusive baryon production as a function of the transverse momentum with respect to the thrust axis. However, this data can in principle be re-analyzed to measure the polarization as a function of the transverse momentum of the baryon with respect to the lepton pair. This observable could be the first significant probe of the function, D T . In this paper, we first develop a TMD formalism for polarization; we then present a recent twist-3 formalism that was established to describe polarization. Using the TMD formalism, we demonstrate that the polarization at OPAL and Belle can be described using the twist-2 TMD factorization formalism. Finally, we make a theoretical prediction for this polarization in the collinear twist-3 formalism at Belle.

72 PHYSICS OF ELEMENTARY PARTICLES AND FIELDS↗

Aberration corrected RF flipper for high resolution neutron spectroscopy

Project Summary Company: Adelphi Technology, Inc. Title: Aberration-corrected High Frequency RF Flipper for High-Resolution Neutron Spectroscopy PI: Dr. Jay Theodore Cremer Topic: C55-11 Enhancement of Scattering Instrumentation Technology Used at Pulsed and Continuous Sources Subtopic: d. Other Statement of the problem or situation that is being addressed. The quest to understand heterogeneous and hierarchical materials is gathering momentum, as described in a 2015 report by the Basic Energy Sciences Advisory Committee on Challenges at the Frontiers of Matter and Energy. For the past 40 years a technique called neutron spin echo (NSE) has been used to probe molecular motions in such non-crystalline materials over time scales from 10’s of picoseconds to 100’s of nanoseconds. The method has provided unique information about the dynamics of soft heterogeneous materials, including confirmation of the de Gennes model of polymer reptation and quantitative measurement of bending constants of biologically relevant lipid membranes. However, scientists continue to clamor for even higher resolution than NSE can provide. Biomaterials, polymers, glasses, and artificially nanostructured materials all manifest slow molecular motions because of weak or competing interactions between subunits and are amenable to study with neutrons, provided sufficiently long dynamical correlation times can be achieved. All these materials have important applications to advanced technologies so understanding them is key to technological progress. General statement of how this problem is being addressed. We will address the need for high-resolution neutron spectroscopy by using a technique called Neutron Resonance Spin Echo (NRSE). While similar to NSE in many respects, this method has the potential to exceed the NSE capabilities, if 2 technical hurdles can be overcome. The major impediments to successful high-resolution NRSE are the availability of two technologies: a very high frequency, efficient, radiofrequency (rf) flipper for neutrons and a method to correct certain magnetic aberrations. Based on previous STTR support and follow-on research we have developed a suitable rf flipper and we have invented a method to correct the magnetic aberrations. Both technologies need refinement to make them suitable for implementation at a neutron source such as the Oak Ridge National Laboratory nuclear reactor. In this proposal we seek to perfect the two technologies and to combine them into a single, operationally convenient device. Commercial Applications and Other Benefits In view of the increasing demand for the unique scientific information that high resolution neutron spectroscopy can provide, we expect several major instrumentation upgrades at both U.S. and foreign neutron centers will require make use of the NRSE method over the coming decade, creating a market for the devices we will design. These components will enhance scientists’ abilities to probe the time dependence of density fluctuations in a wide range of hierarchical and heterogeneous materials many of which are vital to existing and future technologies. Key Words – Polarized Neutrons, Neutron Spin Echo, Neutron Scattering, advanced materials. Summary for Members of Congress Neutron beams are a powerful materials-science probe that provide unique information about the structure of matter. The proposed devices will accelerate scientific discoveries required to achieve national goals for new technological materials.

36 MATERIALS SCIENCE↗

Studying nuclear medium modification using the Gerasimov-Drell-Hearn sum rule

The Gerasimov–Drell–Hearn sum rule is a generic relation that has been used to make significant contributions to research in hadronic physics. It connects the spin-dependent cross-section for photoproduction off a particle to the squared ratio of the particle’s anomalous magnetic moment and its mass, (κ/M)2. Thus, for a nucleon embedded in a nucleus, the sum rule relates the cross-section to κ/M averaged quadratically over the nucleons comprising the nucleus. This quadratic averaging can be used to constrain the mechanism responsible for the medium modification of the nucleon. We also point out that the global properties of the embedded nucleon like its axial charge, mass or magnetic moment are observables measurable through sum rules.

Deur, A. [Thomas Jefferson National Accelerator Fa↗

ECCE sensitivity studies for single hadron transverse single spin asymmetry measurements

Here, we performed feasibility studies for various single transverse spin measurements that are related to the Sivers effect, transversity and the tensor charge, and the Collins fragmentation function. The processes studied include semi-inclusive deep inelastic scattering (SIDIS) where single hadrons (pions and kaons) were detected in addition to the scattered DIS lepton. The data were obtained in pythia6 and geant4 simulated e+p collisions at 18 GeV on 275 GeV, 18 on 100, 10 on 100, and 5 on 41 that use the ECCE detector configuration. Typical DIS kinematics were selected, most notably Q 2 >1 GeV 2 , and cover the x range from 10 -4 to 1. The single spin asymmetries were extracted as a function of x and Q 2 , as well as the semi-inclusive variables z, which corresponds to the momentum fraction the detected hadron carries relative to the struck parton, and P T , which corresponds to the transverse momentum of the detected hadron relative to the virtual photon. They are obtained in azimuthal moments in combinations of the azimuthal angles of the hadron transverse momentum and transverse spin of the nucleon relative to the lepton scattering plane. In order to extract asymmetries, the initially unpolarized MonteCarlo was re-weighted in the true kinematic variables, hadron types and parton flavors based on global fits of fixed target SIDIS experiments and e + e – annihilation data. The expected statistical precision of such measurements is extrapolated to 10 fb –1 and potential systematic uncertainties are approximated given the deviations between true and reconstructed yields. Similar neutron information is obtained by comparing the ECCE e+p pseudo-data with the same from the EIC Yellow Report and scaling the corresponding Yellow Report e+ 3 He pseudo-data uncertainties accordingly. The impact on the knowledge of the Sivers functions, transversity and tensor charges, and the Collins function has then been evaluated in the same phenomenological extractions as in the Yellow Report. Finally, the impact is found to be comparable to that obtained with the parametrized Yellow Report detector and shows that the ECCE detector configuration can fulfill the physics goals on these quantities.

46 INSTRUMENTATION RELATED TO NUCLEAR SCIENCE AND ↗

Effects of spin-orbit-interaction-activated interchannel coupling on photoemission time delay

Here, spin-orbit-interaction-activated interchannel coupling (SOIAIC) has been investigated theoretically in the time delay domain for 3d photoemission in the isoelectronic sequence I – , Xe, and Cs + using the relativistic-random-phase approximation with relaxation. The results show that SOIAIC becomes more important with increasing nuclear charge, and that time delay is affected more strongly than cross sections or photoelectron angular distribution β parameters.

74 ATOMIC AND MOLECULAR PHYSICS↗

Roadmap on nanoscale magnetic resonance imaging

Abstract The field of nanoscale magnetic resonance imaging (NanoMRI) was started 30 years ago. It was motivated by the desire to image single molecules and molecular assemblies, such as proteins and virus particles, with near-atomic spatial resolution and on a length scale of 100 nm. Over the years, the NanoMRI field has also expanded to include the goal of useful high-resolution nuclear magnetic resonance (NMR) spectroscopy of molecules under ambient conditions, including samples up to the micron-scale. The realization of these goals requires the development of spin detection techniques that are many orders of magnitude more sensitive than conventional NMR and MRI, capable of detecting and controlling nanoscale ensembles of spins. Over the years, a number of different technical approaches to NanoMRI have emerged, each possessing a distinct set of capabilities for basic and applied areas of science. The goal of this roadmap article is to report the current state of the art in NanoMRI technologies, outline the areas where they are poised to have impact, identify the challenges that lie ahead, and propose methods to meet these challenges. This roadmap also shows how developments in NanoMRI techniques can lead to breakthroughs in emerging quantum science and technology applications.

Budakian, Raffi↗

Quantum information approach to high energy interactions

High energy hadron interactions are commonly described by using a probabilistic parton model that ignores quantum entanglement present in the light-cone wave functions. Here, we argue that since a high energy interaction samples an instant snapshot of the hadron wave function, the phases of different Fock state wave functions cannot be measured—therefore the light-cone density matrix has to be traced over these unobservable phases. Performing this trace with the corresponding U(1) Haar integration measure leads to ‘Haar scrambling’ of the density matrix, and to the emergence of entanglement entropy. This entanglement entropy is determined by the Fock state probability distribution, and is thus directly related to the parton structure functions. As proposed earlier, at large rapidity η the hadron state becomes maximally entangled, and the entanglement entropy is S E ~η according to QCD evolution equations. When the phases of Fock state components are controlled, for example in spin asymmetry measurements, the Haar average cannot be performed, and the probabilistic parton description breaks down.

73 NUCLEAR PHYSICS AND RADIATION PHYSICS↗

Evolution of Λ polarization in the hadronic phase of heavy-ion collisions

Using the AMPT+MUSIC+URQMD hybrid model, we study the global and local spin polarizations of Λ hyperons as functions of the freeze-out temperature of the spin degree of freedom in the hadronic phase of Au+Au collisions at $\sqrt{s_{NN}}$ = 19.6 GeV. Including contributions from both the thermal vorticity and thermal shear of the hadronic matter, we find that with the spin freeze-out temperature dropping from the hadronization temperature of 160 MeV to 110 MeV at the kinetic freeze-out, both the global and local spin polarizations of Λ hyperons due to the thermal vorticity decrease by a factor of 2, while those due to the thermal shear decrease quickly and become negligibly small at 140 MeV. Here our results thus suggest that it is important to take into account the evolution of the spin degree of freedom in the hadronic stage of relativistic heavy-ion collisions when theoretically predicted global and local Λ spin polarizations are compared with the experimental measurements.

73 NUCLEAR PHYSICS AND RADIATION PHYSICS↗

Final-state interactions and spin structure in E 1 breakup of Li 11 in halo effective field theory

In this work, we calculate the E1 breakup of the 2n halo nucleus 11 Li in halo effective field theory (Halo EFT) at leading order. In Halo EFT, 11 Li is treated as a three-body system of a 9 Li core and two neutrons. We present a detailed investigation of final-state interactions (FSIs) in the neutron-neutron (nn) and neutron-core (nc) channels. We employ Møller operators to formulate an expansion scheme that satisfies the non-energy-weighted cluster sum rule and successively includes higher-order terms in the multiple-scattering series for the FSI. Computing the E1 strength up to third order in this scheme, we observe apparent convergence and good agreement with experiment. The neutron-neutron FSI is by far the most important contribution and largely determines the maximum value of the E1 distribution. However, inclusion of nc FSI does shift the peak position to slightly lower energies. Moreover, we investigate the sensitivity of the E1 response to the spin structure of the neutron- 9 Li interaction. We contrast results for an interaction that is the same in the spin-1 and spin-2 channels with one that is only operative in the spin-2 channel, and find that good agreement with experimental data is only obtained if the interaction is present in both spin channels. The latter case is shown to be equivalent to a calculation in which the spin of 9 Li is neglected.

73 NUCLEAR PHYSICS AND RADIATION PHYSICS↗

Quasiparticle random-phase approximation calculations for M 1 transitions with the noniterative finite-amplitude method and application to neutron radiative capture cross sections

Here, we derive the equations of quasiparticle random-phase approximation (QRPA) based on the finite amplitude method with the Hartree-Fock+Bardeen–Cooper–Schrieffer (HF+BCS) single-particle states, and calculate the magnetic dipole (M⁢1) transition for deformed gadolinium isotopes. Our QRPA calculation shows both large spin-flip transitions in the 5 to 10 MeV excitation energy and the low energy orbital transition that would correspond to the M⁢1 scissors mode observed in nuclear experiments. Then, we calculate neutron capture reactions based on the statistical Hauser-Feshbach theory with the photoabsorption cross sections of even-even nuclei given by QRPA. We find that the capture cross section is enhanced due to the contribution from the low energy M⁢1 transition although the calculated capture cross section still underestimates the experimental data. This issue in the calculated capture cross section could be improved by uncertainties of the low energy E⁢1 transition neglected in our QRPA calculation.

73 NUCLEAR PHYSICS AND RADIATION PHYSICS↗

The Electron-Ion Collider at Brookhaven National Laboratory

The Electron-Ion Collider (EIC), designed by a BNL-TJNAF partnership, will uniquely address three profound questions about nucleons - neutrons and protons, and how they are assembled to form the nuclei of atoms: How does the mass of the nucleon arise? How does the spin of the nucleon arise? What are the emergent properties of dense systems of gluons?

73 NUCLEAR PHYSICS AND RADIATION PHYSICS↗

Longitudinal Solid P Longitudinal Solid Polarized Target for CL get for CLAS12 and Study of Spin AS12 and Study of Spin Structure of Nucleons

A suite of experiments measuring target-spin observables in electron-nucleon scattering (dubbed Run Group C) was conducted at Jefferson Lab's Hall B in Newport News, VA with a new polarized nuclear target known as 'APOLLO' (Ammonia POLarized LOngitudinally). This innovative target is engineered to seamlessly integrate with the advanced 12GeV CEBAF (Continuous Electron Beam Accelerator Facility) accelerator and the Hall B CLAS12 (12 GeV CEBAF Large Acceptance Spectrometer) detector array. The 'APOLLO' target harnesses the power of Dynamic Nuclear Polarization (DNP) to achieve longitudinal polarization of solid ammonia, thereby creating a net polarization in both protons (NH3) and deuterons (ND3). These samples are subjected to a 5 Tesla magnetic field produced by the CLAS12 spectrometer central solenoid, cooled to 1 K using helium evaporation, and subsequently exposed to microwave radiation at a frequency of 140 GHz. This project was made possible through a collaborative partnership between the Jefferson Lab Target Group, Old Dominion University, University of Virginia, Christopher Newport University, and the CLAS Collaboration. Integrating the APOLLO target into CLAS12 presented unique challenges because of its specific spatial and dimensional constraints. This dissertation will highlight the innovative solutions developed to address these challenges, including the creation of a new target material transport system, the incorporation of superconducting magnetic correction coils, and the development of a customized Nuclear Magnetic Resonance (NMR) system. In addition to a detailed description of the development and operation of APOLLO, and an overview of RGC, this document also describes the global data fitting of proton asymmetries in the Deep Inelastic scattering (DIS) and the Resonance regions, and it offers insights into the comprehensive analysis of target polarization data.

Pandey, Pushpa↗