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Managing Content in a Matter of Minutes

NASA software created to help scientists expeditiously search and organize their research documents is now aiding compliance personnel, law enforcement investigators, and the general public in their efforts to search, store, manage, and retrieve documents more efficiently. Developed at Ames Research Center, NETMARK software was designed to manipulate vast amounts of unstructured and semi-structured NASA documents. NETMARK is both a relational and object-oriented technology built on an Oracle enterprise-wide database. To ensure easy user access, Ames constructed NETMARK as a Web-enabled platform utilizing the latest in Internet technology. One of the significant benefits of the program was its ability to store and manage mission-critical data.

Source record↗

Report of the Panel on Propulsion

Propulsion, while conventionally included on the list of important aeronautical disciplines along with aerodynamics, structures, etc., is in itself a systems endeavor, analogous to the engineering of the entire vehicle; indeed propulsion encompasses important aspects of all the other disciplines. In recognition of this fact, the panel focused its discussion on those aspects of the key disciplines that are especially or uniquely important to propulsion. From the initial development of the airplane, the propulsion system has been recognized as one of the pacing technologies. It is perhaps because of the technological disparity between the reciprocating engine and the primitive airframe that the two remained relatively and separate, were developed somewhat independently, usually by different organizations. In recent years, the maturing of the gas turbine power plant and the advance in high-speed airframes have rendered this separation somewhat artificial. The power plant and the airframe now share common structural and aerodynamic elements; as the flight Mach number rises, the degree of interaction increases. By the year 2000, this interdependence will have increased in many respects to a point where independent design may not be practical or possible. During the period since the initiation of the aircraft gas turbine, the solid propellant rocket and the liquid propellant rocket, a vast array of other novel engines have been studied, covering the full spectrum of flight conditions from low subsonic to hypersonic and transatmospheric flight. In each instance, performance limits have been investigated under the assumption that current technology or reasonably foreseeable technology would be available for their development. Among the extensive list of advanced, high-performance concepts and cycles examined are the hypersonic ramjet, the variable cycle, runway-to-orbit airbreathing engine, the ram rocket (airbreathing and rich solid propellant rocket), and the air turborocket. At various times, these systems have come relatively close to meriting development and application. In many instances, limitations of materials and technologies curtailed development. As important and with almost equal frequency, the lack of commercial or military utility of the concept precluded the necessary funding. It is instructive to note that two former items on this list, the turbofan (bypass engine) and the high-speed turboprop, are respectively a mainstay engine and a promising development. In the case of the turbofan, its full potential could not be realized until turbine cooling technology had been developed and new materials developed to permit the construction of transonic fans. In the case of the highspeed turbopropeller engine, not only were the material and turbine technologies needed, but, in addition, the rise in fuel costs provided the impetus to take advantage of its favorable fuel consumption characteristic. As the basic technologies progress and as new missions become attractive, the engines in the foregoing list become candidates for new feasibility studies and further technology development. At the present time, the ram rocket is the prime contender to augment the range of small missiles. Of interest also is the hypersonic ram jet and its logical extension, the runway-to-orbit airbreathing engine. Much of this report deals with the development of current or near-future power plant concepts. First, the motivating factors for aeronautical propulsion research are reviewed as a reminder of the importance of continued effort in a field that has often been characterized as mature. Next, technical areas are discussed in which the panel feels additional research effort is warranted and would lead to the realization of the technological potentials between now and the year 2000. Under these guidelines, new cycles (e.g., isothermal energy exchange) were not considered by the panel. Finally, although facility requirements were not a prime consideration in the current projections, the panel believes that the increasing complexity of propulsion systems; the need for more refined interaction between propulsion system, airframe, and controls; and increasing operation in adverse weather will require test capabilities beyond those now available (see appendix). Enhanced test capability is needed in the areas of propulsion airframe integration and in largescale icing research with proper concurrent treatment of altitude, temperature, and speed.

Kerrebrock, Jack L.↗

Factors Governing Oxygen Vacancy Formation in Oxide Perovskites

The control of oxygen vacancy (V O ) formation is critical to advancing multiple metal-oxide-perovskite-based technologies. In this work, we report the construction of a compact linear model for the neutral V O formation energy in ABO 3 perovskites that reproduces, with reasonable fidelity, Hubbard-U-corrected density functional theory calculations based on the state-of-the-art, strongly constrained and appropriately normed exchange-correlation functional. We obtain a mean absolute error of 0.45 eV for perovskites stable at 298 K, an accuracy that holds across a large, electronically diverse set of ABO 3 perovskites. Our model considers perovskites containing alkaline-earth metals (Ca, Sr, and Ba) and lanthanides (La and Ce) on the A-site and 3d transition metals (Ti, V, Cr, Mn, Fe, Co, and Ni) on the B-site in six different crystal systems (cubic, tetragonal, orthorhombic, hexagonal, rhombohedral, and monoclinic) common to perovskites. Physically intuitive metrics easily extracted from existing experimental thermochemical data or via inexpensive quantum mechanical calculations, including crystal bond dissociation energies and (solid phase) reduction potentials, are key components of the model. Beyond validation of the model against known experimental trends in materials used in solid oxide fuel cells, the model yields new candidate perovskites not contained in our training data set, such as (Bi,Y)(Fe,Co)O 3 , which we predict may have favorable thermochemical water-splitting properties. The confluence of sufficient accuracy, efficiency, and interpretability afforded by our model not only facilitates high-throughput computational screening for any application that requires the precise control of V O concentrations but also provides a clear picture of the dominant physics governing V O formation in metal-oxide perovskites.

08 HYDROGEN↗

Exploration of advanced porous organic polymers as a platform for biomimetic catalysis and molecular recognition

Nature has long been a dominant source of inspiration in the area of chemistry, serving as prototypes for the design of materials with proficient performance. In this Feature article, we present our efforts to explore porous organic polymers (POPs) as a platform for the construction of biomimetic materials to enable new technologies to achieve efficient conversions and molecular recognition. For each aspect, we first present the chemical basis of nature, followed by depicting the principles and design strategies involved for functionalizing POPs along with a summary of critical requirements for materials, culminating in a demonstration of unique features of POPs. Our endeavours in using POPs to address the fundamental scientific problems related to biomimetic catalysis and adsorption are then illustrated to show their enormous potential and capabilities for applications ranging from concerted catalysis to radionuclide sequestration. To conclude, we present a personal perspective on the challenges and opportunities in this emerging field.

37 INORGANIC, ORGANIC, PHYSICAL, AND ANALYTICAL CH↗

PRODeepSyn: predicting anticancer synergistic drug combinations by embedding cell lines with protein–protein interaction network

Abstract Although drug combinations in cancer treatment appear to be a promising therapeutic strategy with respect to monotherapy, it is arduous to discover new synergistic drug combinations due to the combinatorial explosion. Deep learning technology holds immense promise for better prediction of in vitro synergistic drug combinations for certain cell lines. In methods applying such technology, omics data are widely adopted to construct cell line features. However, biological network data are rarely considered yet, which is worthy of in-depth study. In this study, we propose a novel deep learning method, termed PRODeepSyn, for predicting anticancer synergistic drug combinations. By leveraging the Graph Convolutional Network, PRODeepSyn integrates the protein–protein interaction (PPI) network with omics data to construct low-dimensional dense embeddings for cell lines. PRODeepSyn then builds a deep neural network with the Batch Normalization mechanism to predict synergy scores using the cell line embeddings and drug features. PRODeepSyn achieves the lowest root mean square error of 15.08 and the highest Pearson correlation coefficient of 0.75, outperforming two deep learning methods and four machine learning methods. On the classification task, PRODeepSyn achieves an area under the receiver operator characteristics curve of 0.90, an area under the precision–recall curve of 0.63 and a Cohen’s Kappa of 0.53. In the ablation study, we find that using the multi-omics data and the integrated PPI network’s information both can improve the prediction results. Additionally, the case study demonstrates the consistency between PRODeepSyn and previous studies.

Wang, Xiaowen↗

Progress in the Development of the Nb 3 Sn MQXFB Quadrupole for the HiLumi Upgrade of the LHC

The high-luminosity upgrade of the Large Hadron Collider (HL-LHC) requires new high field and large-aperture quadrupole magnets for the low-beta inner triplets (MQXF). With a nominal operating gradient of 132.2 T/m in a 150 mm aperture and a conductor peak field of 11.3 T, the new quadrupole magnets are based on Nb 3 Sn superconducting technology. After a series of short models constructed in close collaboration by LARP (LHC Accelerator Research Program) and CERN, the development program is entering in the series production phase with CERN on one side and the US Accelerator Upgrade Project (US-AUP) on the other side assembling and testing full-length magnets. This paper describes the status of the development activities at CERN, in particular on the cold powering test of the first MQFXB prototype and on the construction of the second full scale prototype. Critical operations such as reaction heat treatment, coil impregnation and magnet assembly are discussed. Finally, the plan towards the series production is described.

43 PARTICLE ACCELERATORS↗

Energy Efficient Thermoplastic Composite Manufacturing

The objective of the project was to establish an effective and affordable method to lay-up and consolidate/join large thermoplastic composite aerospace structure with cycle times measured in minutes rather than hours. Composite airplane designs have proven efficient and effective however future potential product production rates are challenging what the current systems can efficiently produce due to material lay-down constraints and extended thermal cycle times. The ability to lay-up then rapidly heat, consolidate, and cool large complex composite structures plus very accurately tool them (i.e. matching CTE of composite materials) along with very precise thermal control is a difficult challenge. Current systems such as autoclave processing of thermoset materials require long cycle times due to method of heating and the large associated thermal masses. These extended cycle times inhibit the ability to meet higher rate production scenarios due to the need for multiple sets of equipment and tools. Thermoplastic composite materials were used to facilitate more rapid cycle times via the elimination of a need for a cure dwell at temperature. Also, utilized induction heating along with smart susceptors to enable the quick cycle times needed while providing precise intrinsic thermal control. The intrinsic control of the induction heating process via the smart susceptors along with the use of laser assisted fiber placement were the key innovations areas developed. The ability to rapidly heat and then precisely control the temperature of the consolidation component was paramount to the success of this project. It is this unique processing attribute coupled with the thermoplastic material characteristics along with rapid lay-up methods that are novel and advantageous. While many requirements and influencing factors decide the materials and processes utilized for future airplane construction, the forecast of accelerated production rates and the recent performance successes of composites in airplane construction provide an opportunity for this processing technology to have significant influence. During the course of this project a number of key accomplishments were completed. They are as follows: The needed laser assisted fiber placement capabilities have been developed and validated on a component of meaningful scale and complexity. Subsequently, a thermoplastic preform of the part scale-up part design was laser assisted fiber placed and made availalbe for consolidation. An induction consolidation system was sized, designed, and fabricated resulting in the full capability to consolidate the scale-up component. The tool for induction consolidating of the scale-up component was designed and fabricated. An aluminum pressure bladder was welded and formed for use as the pressurization membrane to perform the needed application of pressure on the part at temperature to achieve consolidation. The induction consolidation system consisting of the restraint, induction power supply, induction tool with integrated induction coils and smart susceptor liners, along with the aluminum bladder were successfully used to consolidate a large thermoplastic skin. The capability of accomplishing rapid heat-up rates and cool down rates for consolidation of large thermoplastic skins with precise thermal control and even pressure application at the consolidation temperature was validated. The general conclusion is that the use of induction consolidation with smart susceptors is an effective method to rapidly and efficiently consolidate large thermoplastic composite components and enable affordable high rate manufacturing of composites. More specific conclusions generated by this project are as follows: A restraint type induction consolidation system provides an affordable option over the standard press when using the induction consolidation processing method. Aluminum bladders can be formed to the complex shapes needed and supply uniform pressure for consolidation and co-consolidation of thermoplastic composite materials. Straightforward modifications can be made to existing fiber placement robotic systems to enable their use for thermoplastic lay-up applications.

32 ENERGY CONSERVATION, CONSUMPTION, AND UTILIZATI↗

Environmental and Circular Economy Implications of Solar Energy in a Decarbonized U.S. Grid

This report addresses environmental and circular economy (CE) considerations related to solar technologies via novel analysis of the three Solar Futures core scenarios as well as synthesis of published research. We organize these issues into the three basic life cycle phases of a solar technology: manufacturing, operation (including site selection and construction), and EOL. Related environmental justice issues are also explored. Finally, we recommend research and development (R&D) activities that could help clarify challenges and identify solutions. Because PV deployment is projected to be much larger than CSP deployment, we offer a more detailed analysis of PV-related issues.

14 SOLAR ENERGY↗

Commissioning of the IOTA Proton Injector

The Proton Injector for the IOTA storage ring (IPI) is being constructed at the Fermilab Accelerator Science and Technology facility (FAST). It will be a machine capable of delivering 20 mA pulses of protons at 2.5 MeV. IPI will operate alongside the existing electron injector beamline to facilitate further beam physics research and the continued development of novel accelerator technologies at the IOTA ring. This report details the results of the initial commissioning of IPI and an overview of the upcoming experiments with intense proton beams at IOTA.

43 PARTICLE ACCELERATORS↗

Recommendations to Improve Nuclear Licensing: Update to INL/RPT-23-72206, Recommendations to Improve the Nuclear Regulatory Commission Reactor Licensing and Approval Process

In 2023, various stakeholders had asked for BEA’s thoughts and recommendations to improve the U.S. Nuclear Regulatory Commission’s (NRC) licensing review and approval process. This included an April 14, 2023 request from the House Committee on Energy and Commerce on “information and recommendations to improve the licensing review and approval process, . . . as well as the siting, licensing, construction, and oversight of advanced nuclear reactor technologies.” In response to these requests, BEA prepared and published INL/RPT-23-72206, Recommendations to Improve the Nuclear Regulatory Commission Reactor Licensing and Approval Process (2023 Report). The 2023 Report included 13 recommendations related to streamlining NRC hearings, expediting NRC safety and environmental reviews, otherwise improving NRC licensing, and providing financial benefits to new reactor projects. Many of these earlier recommendations were addressed through various legislative actions or changes made by the NRC. Section 2 of this report addresses the current status of those earlier recommendations. BEA recently received a new request from the House Committee on Energy and Commerce seeking any suggestions for additional areas to examine or potential reforms “that may assist in modernizing the licensing and regulatory process that affects civil nuclear deployment.” Additionally, the new Secretary of Energy has identified initial DOE actions to support unleashing the golden era of American energy dominance, including “Unleash Commercial Nuclear Power in the United States” and “Streamline Permitting and Identify Undue Burdens on American Energy.” Given these developments, BEA has prepared a new set of updated recommendations in this report. The recommendations include updated versions of recommendations from the 2023 Report which have not been fully adopted, as well as entirely new recommendations. This set of recommendations has a slightly broader focus with some recommendations focused on DOE authorizations and some recommendations related to nuclear licensing beyond new reactors. Each recommendation below also identifies whether the recommendation would require legislative action or could be addressed directly by the respective agency.

22 GENERAL STUDIES OF NUCLEAR REACTORS↗

Use of active control technology to improve ride qualities of large transport aircraft

Analyses, construction and flight testing of two systems: Beta-vane and Modal Suppression Augmentation System (MSAS), which were developed to suppress gust induced lateral accelerations of large aircraft, are described. The 747 transport was used as the test vehicle. The purpose of the Beta-vane system is to reduce acceleration levels at the dutch roll frequency whereas the function of the MSAS system is to reduce accelerations due to flexible body motions caused by turbulence. Data from flight test, with both systems engaged shows a 50 to 70 percent reduction in lateral aft body acceleration levels. Furthermore, it is suggested that present day techniques used for developing dynamic equations of motion in the flexible mode region are limited.

Cohen, G. C.↗

Space industrialization - Education

The components of an educational system based on, and perhaps enhanced by, space industrialization communications technology are considered. Satellite technology has introduced a synoptic distribution system for various transmittable educational media. The cost of communications satellite distribution for educational programming has been high. It has, therefore, been proposed to utilize Space Shuttle related technology and Large Space Structures (LSS) to construct a system with a quantum advancement in communication capability and a quantum reduction in user cost. LSS for communications purposes have three basic advantages for both developed and emerging nations, including the ability to distribute signals over wide geographic areas, the reduced cost of satellite communications systems versus installation of land based systems, and the ability of a communication satellite system to create instant educational networks.

Joels, K. M.↗

Preparing for the future

Technologies and programs related to the development, construction, and operation of the Space Station are examined. A phase approach has been chosen for the construction of the Space Station, which is to have a revised baseline configuration. Consideration is given to the use of automation on the Space Station; the assembly and servicing of the Station; user requirements; and Space Station operations. The benefits the Space Station will provide to space exploration are discussed.

Stofan, Andrew J.↗

Microtronic Flow Transducer

Novel microelectronic airflow and gas-flow transducer developed. Has no moving parts and constructed by use of variation on ordinary technology for processing of planar silicon microelectronics, where hundreds or thousands of identical devices concurrently produced on single chip as easily as can one. Gas-flow transducer based upon integrated Wheatstone bridge in silicon chip. Legs doped with gold and isolated thermally by etching away surrounding material (except corners). Because of small size, sensitivity, and good directional capability of new transducer, numerous potential applications in measurement of vortexes, flows in inlets to pipes, and other complicated flows.

Sundberg, Gale R.↗

Orbiting transmitter and antenna for spaceborne communications at ELF/VLF to submerged submarines

An orbital emplacement for the transmitter and the antenna of a communications link at ELF (30 to 300 Hz) and VLF (3 kHz to 30 kHz) to submerged submarines has been considered since the very inception of the space age. However, only recently has space technology reached a sufficient level of maturity for system designers to undertake serious studies of this link configuration. The optimistic outlook stems from recent space technology developments, such as the design and construction by NASA of long orbiting tethers, and the testing, onboard Shuttle Orbiter ATLANTIS, of the first spaceborne 20 km metal wire. This is known as the Tethered Satellite System-1 (TSS-1), a space mission that might be possibly followed by other flights, with tether lengths that could reach 100 km. Once deployed at a height of, say, 300 km, from a Shuttle Orbiter, or from another suitable platform, a long, thin tether aligns itself along the local vertical by virtue of the gradient of the Earth gravity field. If made of metal, the tether can function as a VED (Vertical Electric Dipole) transmitting antenna at ELF and VLF.

Bannister, P. R.↗

Defocussing characteristics of the ACTS, T1-VSAT Earth terminal antennas

This report describes a study, the purpose of which was to determine the characteristics of two reflector antennas, as the reflector feed is moved away from the focus. The antennas are a 1.2 meter and a 2.44 meter reflector that will be used in the T1-VSAT earth terminals for the Advanced Communications Technology Satellite (ACTS). These terminals have been constructed in such a way that is inconvenient to use attenuators to control the gain of the signal that is directed toward the satellite. Feed defocusing was proposed as a simple, convenient way to achieve the required gain control. The study was performed in two parts. In order to determine the feasibility of the technique, a theoretical analysis was performed to obtain the gain, beamwidth and far-field pattern of the antennas, as a function of feed displacement. An experimental investigation followed in which patterns of the 1.2 meter antenna were obtained through measurement in the NASA Lewis Research Center, Near-Field Antenna Test Facility. Results of the theoretical and experimental investigation are presented for both uplink (30 GHz) and downlink (20 GHz) frequencies.

Lambert, Kevin M.↗