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At least 649 records · Page 36

Cerebellar pressor response in the dog

A fastigial pressor response has been elicited in the anesthetized mongrel dog. Stimulation within the rostral portions of this nucleus results in mean arterial pressure rises up to 150 mmHg above control. A proportional tachycardia is simultaneously evoked which may rapidly attain heart rates of 190 beats/min above control levels. Peak tachycardias immediately subside and often the heart rate declines below control values during stimulation while arterial pressure remains elevated. When either the carotid sinuses were isolated by ligation or a bilateral vagotomy was performed, the fastigial tachycardia was sustained. The response could still be attained when submaximal doses of alpha-chloralose anesthesia or high levels of barbiturates (30-40 mg/kg) were given. Both portions of the response result from widespread sympathetic activation; however, buffering of the response through the baroreceptor reflexes is only demonstrated in the cardiac segment of the response.

Dormer, K. J.↗

Electric utility companies and geothermal power

The requirements of the electric utility industry as the primary potential market for geothermal energy are analyzed, based on a series of structured interviews with utility companies and financial institution executives. The interviews were designed to determine what information and technologies would be required before utilities would make investment decisions in favor of geothermal energy, the time frame in which the information and technologies would have to be available, and the influence of the governmental politics. The paper describes the geothermal resources, electric utility industry, its structure, the forces influencing utility companies, and their relationship to geothermal energy. A strategy for federal stimulation of utility investment in geothermal energy is suggested. Possibilities are discussed for stimulating utility investment through financial incentives, amelioration of institutional barriers, and technological improvements.

Pivirotto, D. S.↗

Photocatalytic oxidation of organic compounds on Mars

Ultraviolet-stimulated catalytic oxidation is proposed as a mechanism for the destruction of organic compounds on Mars. The process involves the presence of gaseous oxygen, UV radiation, and a catalyst (titanium dioxide), and all three of these have been found to be present in the Martian environment. Therefore it seems plausible that UV-stimulated oxidation of organics is responsible for degrading organic molecules into inorganic end products.

Chun, S. F. S.↗

Interpretation of satellite gyroharmonic resonance observations

An analytical expression is obtained for the rendezvous conditions between a propagating wave near nfH and a moving ionospheric sounder antenna, where fH is the ambient value of the electron gyrofrequency and n is an integer greater than 1. The agreement between the theoretical predictions and Alouette 1 satellite observations indicates that most of the long duration resonances (those with durations greater than about 2 msec) can be interpreted in terms of the reception of sounder-stimulated electrostatic waves that are reflected and returned to the sounder antenna. The results provide a technique for obtaining from sounder-stimulated plasma resonances information on ambient electron temperature corresponding to electron motions perpendicular to the ambient magnetic field.

Benson, R. F.↗

Effects of hirudin-induced activation of nonenzymatic fibrinolysis during immobilization stress

The specific inhibitor of thrombin, hirudin, was used for studying the mechanism of the activating effect of ACTH and adrenalin on nonenzymatic fibrinolytic activity (NEFA), the latter characterizing the function of the anticoagulation system (ACS). Simultaneous administration of ACTH and hirudin to animals subjected to immobilization stress did not reduce the effect of ACTH on NEFA, while simultaneous administration of adrenalin and hirudin revealed a diminished effect of the former. This suggests different mechanisms of ACTH and adrenalin effects upon NEFA: the stimulating effect of norepinephrine is realized through throminogenesis followed by activation of the ACS function and by increased NEFA and therefore inhibitable by hirudin which forms an inactive complex with thrombin. In fact the stimulating effect of ACTH upon NEFA is brought about specifically by another route than thrombinogenesis and thus occurs in the presence of hirudin. Hirudin itself has no effect upon NEFA.

Shapiro, F. B.↗

Some influences of vision on susceptibility to motion sickness

Two experiments were performed to evaluate the influence of vision on susceptibility to motion sickness during exposure to constant patterns of vestibular stimulation. The motion profile involved accelerating subjects at 20 deg/sec per sec to 300 deg/sec, maintaining them at that constant velocity for 30 sec, and decelerating them to a rapid stop in about 1.5 sec. The number of stops tolerated by a subject before reaching the motion sickness endpoint served as his score. In Experiment 1, subjects were tested twice with their eyes open and twice with their eyes blindfolded. They tolerated fewer sudden stops when permitted sight of the experimental chamber. In Experiment 2, the effect of having the eyes open or closed at different stages of the motion profile was evaluated. Having the eyes open during any stage of the test was more stressful than having the eyes closed, but this was especially true during the sudden stops. The findings are discussed in terms of their general implications for understanding (1) situations in which vision alone elicits symptoms of motion sickness, and (2) situations involving vestibular stimulation where vision heightens susceptibility.

Lackner, J. R.↗

Choice reaction time to movement of eccentric visual targets during concurrent rotary acceleration

This study investigates the influence of concurrent rotary acceleration on choice reaction time (RT) to a small, accelerating visual cursor on a cathode-ray tube. Subjects sat in an enclosed rotating device at the center of rotation and observed a 3-mm dot accelerating at different rates across a cathode-ray tube. The dot was viewed at various eccentricities under conditions of visual stimulation alone and with concurrent rotary acceleration. Subjects responded to both vertical and horizontal dot movements. There was a significant inverse relationship between choice RT and level of dot acceleration (p less than .001), and a significant direct relationship between choice RT and eccentricity (p less than .001). There was no significant difference between choice RT to vertical or horizontal dot motion (p greater than .25), and choice RT was not significantly affected by concurrent rotary acceleration (p greater than .10). The results are discussed in terms of the effects of vestibular stimulation on choice RT to visual motion.

Hamerman, J. A.↗

Comparison of early reactions of the blood system in rats to immobilization, the action of hypoxia and the administration of erythopoietin

Three series of experiments were simultaneously carried on rats with the purpose of studying the action of different stimulants on the blood system; rats were subjected to immobilization, hypoxic hypoxia and erythropoietin administration. Changes in various cellular forms in the bone marrow, the thymus and the spleen were studied. A unitypical reaction, as in stress, was noted during the first hours; a reduction of the cell count in the lymphoid organs, a reduction of granulocytes and an increase of lymphoid cells in the bone marrow. The differences were chiefly quantitative. This was followed by stimulation of myelo and erythropoiesis determined by the specific features of the action applied. Nonspecific blood reaction was apparently due to activation of the adaptation mechanisms.

Gorizontov, P. D.↗

Plasma volume, osmolality, vasopressin, and renin activity during graded exercise in man

The influence of work intensity on plasma volume, osmolality, vasopressin and renin activity and the interrelationships between these responses are investigated. Plasma volume, renin activity and osmotic, sodium and arginine vasopressin concentrations were measured in venous blood samples taken from 15 healthy male subjects before and after six minutes of bicycle ergometer exercise at 100, 175 and 225 W. Plasma volume is found to decrease significantly with increasing work intensity, while increases in Na(+) concentration, osmolality and vasopressin are only observed to be significant when the work intensity exceeds 40% maximal aerobic capacity and plasma resin activity increased linearly at all work levels. In addition, significant correlations are observed between plasma volume and osmolality and sodium changes, and between vasopressin and osmolality and sodium content changes. Data thus support the hypotheses that (1) vasopressin may be the primary controlling endocrine for fluid and electrolyte levels following exercise; (2) an exercise intensity greater than 40% maximal aerobic capacity is required to stimulate vasopressin release through changes in plasma osmolality; and (3) the stimulation of the renin-angiotensin system is a more general stress response.

Convertino, V. A.↗

Power line radiation in the magnetosphere

Harmonic radiation from electrical power transmission lines in the range of a few kHz leaks into the magnetosphere and stimulates a coherent wave instability, resulting in strong amplification of the input waves and the generation of free-running emissions. A description is given of some recent observational results that provide new information on the power line radiation (PLR) phenomenon. It is pointed out that PLR stimulates many subtle and complex wave-particle interactions in the magnetosphere that are similar to those simulated by controlled transmitter signals. These interactions undoubtedly affect both wave and particle environments in the magnetosphere. However, a quantitative assessment of their importance is not possible until further information becomes available.

Park, C. G.↗

The persistence of a visual dominance effect in a telemanipulator task: A comparison between visual and electrotactile feedback

The possibility to use an electrotactile stimulation in teleoperation and to observe the interpretation of such information as a feedback to the operator was investigated. It is proposed that visual feedback is more informative than an electrotactile one; and that complex electrotactile feedback slows down both the motor decision and motor response processes, is processed as an all or nothing signal, and bypasses the receptive structure and accesses directly in a working memory where information is sequentially processed and where memory is limited in treatment capacity. The electrotactile stimulation is used as an alerting signal. It is suggested that the visual dominance effect is the result of the advantage of both a transfer function and a sensory memory register where information is pretreated and memorized for a short time. It is found that dividing attention has an effect on the acquisition of the information but not on the subsequent decision processes.

Gaillard, J. P.↗

Effects of rectilinear acceleration, optokinetic and caloric stimuli in space

The set of experiments comprising the Spacelab 1ES201 package designed to investigate the human vestibular system and equilibratory function in weightlessness are described. The specific objectives of the experiments include: (1) the determination of the threshold of perception of linear oscillatory motion; (2) measurement of physiological and subjective responses to supra threshold, linear and angular motion stimuli; (3) study of the postural adjustments, eye movements, and illusions of attitude and motion evoked by optokinetic stimuli, (i.e., moving visual patterns) in order to assess visual/vestibular interactions; (4) examination of the effect of thermal stimulations of the vestibular apparatus to determine if the eye movements elicited by the 'caloric test' are used by a density gradient in the semicircular canal; and (5) investigation of the pathogenesis of space motion sickness by recording signs and symptoms during the course of vestibular stimulation and, specifically, when the test subject is exposed to sustained, linear oscillatory motion.

Vonbaumgarten, R.↗

VLF wave growth and discrete emission triggering in the magnetosphere - A feedback model

A simple nonlinear feedback model is presented to explain VLF wave growth and emission triggering observed in VLF transmission experiments. The model is formulated in terms of the interaction of electrons with a slowly varying wave in an inhomogeneous medium as in an unstable feedback amplifier with a delay line; constant frequency oscillations are generated on the magnetic equator, while risers and fallers are generated on the downstream and upstream sides of the equator, respectively. Quantitative expressions are obtained for the stimulated radiation produced by energy exchanged between energetic electrons and waves by Doppler-shifted cyclotron resonance, and feedback between the stimulated radiation and the phase bunched currents is incorporated in terms of a two-port discrete time model. The resulting model is capable of explaining the observed temporal growth and saturation effects, phase advance, retardation or frequency shift during growth in the context of a single parameter depending on the energetic particle distribution function, as well as pretermination triggering.

Helliwell, R. A.↗

EXOS-B/Siple Station VLF wave-particle interaction experiment

Preliminary results of experiments made using the EXOS-B satellite to make simultaneous observations of VLF signals transmitted from Siple Station, Antarctica and interacting particles are reported. VLF measurements carried out by the EXOS-B wideband receiver upon satellite crossings of the Siple meridian at equatorial and high latitudes were able to detect the Siple signal on about 50% of the passes, and observed four instances of artificially stimulated emissions. Two of these cases exhibit triggering with a clear relation to the transmitted frequency format, while in the remaining two this relation is absent. Electron fluxes at energies from 3 eV to 9.5 keV are observed to be enhanced during the Siple stimulated emission events, with a distribution on the equatorial passes sufficient to satisfy the cyclotron interaction condition for parallel propagation of Siple signals of frequency about half the local cyclotron frequency.

Kimura, I.↗

Cloning higher plants from aseptically cultured tissues and cells

A review of aseptic culture methods for higher plants is presented, which focuses on the existing problems that limit or prevent the full realization of cloning plants from free cells. It is shown that substantial progress in clonal multiplication has been made with explanted stem tips or lateral buds which can be stimulated to produce numerous precocious axillary branches. These branches can then be separated or subdivided and induced to root in order to yield populations of genetically and phenotypically uniorm plantlets. Similarly, undifferentiated calluses can sometimes be induced to form shoots and/or roots adventitiously. Although the cell culture techniques required to produce somatic embryos are presently rudimentary, steady advances are being made in learning how to stimulate formation of somatic or adventive embryos from totipotent cells grown in suspension cultures. It is concluded that many problems exist in the producing and growing of totipotent or morphogenetically competent cell suspensions, but the potential benefits are great.

Krikorian, A. D.↗

Plasma volume, renin, and vasopressin responses to graded exercise after training

Four male subjects underwent a series of ergometer trials to test the hypothesis that training-induced hypervolemia produces a reduction in the relative change of plasma volume, vasopressin, and renin activity levels. Sitting ergometer exercise was performed for 2 hr per day for 8 consecutive days and the VO2 was monitored. A second phase involved a graded exercise and recording of the VO2 and HR, as well as the taking of blood samples to measure the plasma osmolality, the vasopressin content, and the renin activity. The training was found to reduce the plasma volume levels for a given work load. Hypervolemia was induced by a training-produced plasma volume expansion. The osmolality, vasopressin content, and renin activity increased with training. A threshold work intensity of 50 percent was identified for changes in the osmolality and the stimulation of renin activity and vasopressin increase. The maintenance of a certain level of intensity during training is concluded necessary to stimulate the hypervolemic response.

Convertino, V. A.↗

Instrumentation, data acquisition and reduction for a large spaceborne helium dewar

The data acquisition system monitors five types of transducers: (1) platinum and germanium resistance thermometers; (2) superconducting liquid level indicators for both cryogen tanks; (3) pressure transducers for both tanks; (4) strain gauges at critical structural locations; and (5) flowmeters for monitoring cryogen tank boiloff which are linear voltage output transducers. All the transducers produce a voltage proportional to the parameter they measure; this is routed to a single six and one-half digit voltmeter by way of an 80-channel multiplexer. The data acquisition program has six main functions: (1) definition and modification of the channels to be stimulated; (2) sensor stimulation and measurement; (3) raw data storage; (4) raw data conversion; (5) real-time formatting and output of raw or converted data; and (6) editing. The heart of the program is a driver section that represents approximately 20 percent of the code. The driver mode sequences and controls the six main functions.

Brooks, W. F.↗

Evidence for a Regulatory Role of Calcium in Gravitropism

Experiments conducted to determine the cellular basis of gravitropism, the phenomenon of calcium migration following gravitropic stimulation, and the preferential accumulation of calcium in cells are described. Results of autoradiographic studies of cross sections of oat, and the pryoantimony precipitation of calcium in situ are discussed. It was found that the movement of calcium during gravimetric stimulation is a redistribution of calcium from the vacuolar regions into the cells walls. This movement requires precipitation of a calcium ATPase. The control of calcium ATPase by calmodulin and whether chlorpromazine is binding to calmodulin in plants are considered.

Roux, S. J.↗