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Search indexed NASA NTRS and DOE OSTI research on propulsion, heat transfer, battery materials and energy systems. Follow report and document links to the original sources.

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At least 649 records · Page 36
All sourcesNASA NTRSDOE OSTI
DOE OSTI2022

Production of GMP-Compliant Clinical Amounts of Copper-61 Radiopharmaceuticals from Liquid Targets

PET imaging has gained significant momentum in the last few years, especially in the area of oncology, with an increasing focus on metal radioisotopes owing to their versatile chemistry and favourable physical properties. Copper-61 (t1/2 = 3.33 h, 61% β+, Emax = 1.216 MeV) provides unique advantages versus the current clinical standard (i.e., gallium-68) even though, until now, no clinical amounts of 61Cu-based radiopharmaceuticals, other than thiosemicarbazone-based molecules, have been produced. This study aimed to establish a routine production, using a standard medical cyclotron, for a series of widely used somatostatin analogues, currently labelled with gallium-68, that could benefit from the improved characteristics of copper-61. We describe two possible routes to produce the radiopharmaceutical precursor, either from natural zinc or enriched zinc-64 liquid targets and further synthesis of [61Cu]Cu-DOTA-NOC, [61Cu]Cu-DOTA-TOC and [61Cu]Cu-DOTA-TATE with a fully automated GMP-compliant process. The production from enriched targets leads to twice the amount of activity (3.28 ± 0.41 GBq vs. 1.84 ± 0.24 GBq at EOB) and higher radionuclidic purity (99.97% vs. 98.49% at EOB). Our results demonstrate, for the first time, that clinical doses of 61Cu-based radiopharmaceuticals can easily be obtained in centres with a typical biomedical cyclotron optimised to produce 18F-based radiopharmaceuticals.

Fonseca, Alexandra I. (ORCID:000000031924178X)↗
NASA NTRS1980

The visual accommodation response during concurrent mental activity

The direction and magnitude of the human visual accommodation response during concurrent mental activity are investigated. Subject focusing responses to targets at distances of 0.0 D, 3.0 D and an indeterminate distance were monitored by means of an optometer during the performance of a backwards counting task and a visual imagery task (thinking near and thinking far). In both experiments a shift in accommodation towards the visual far point is observed particularly for the near target, which increases with the duration of the task. The results can be interpreted in terms of both the capacity model of Kahneman (1973) and the autonomic arousal model of Hess and Polt (1964), and are not inconsistent with the possibility of an intermediate resting position.

Malmstrom, F. V.↗
NASA NTRS2003

Comparison of Measured and Simulated Albedo Signals in the ATIC Experiment

Albedo, radiation backscattered from an interaction and from the subsequent shower development, provides a 'background' for calorimeter experiments. In ATIC (Advanced Thin Ionization Calorimeter), a balloon borne instrument to measure cosmic ray composition and energy spectra for elements from hydrogen to iron from 30 GeV to near 100 TeV, a fully active BGO calorimeter follows a carbon interaction target and scintillator holdoscopes. The first detector is a silicon matrix constructed of 4480 individual silicon pixels, each 2 cm x 1.5 cm, that provide a measurement of the charge of the primary particle in the presence of albedo. ATIC had two successful balloon flights in Antarctica: from 28 Dec 2000 to 13 Jan 2001 (ATIC-1) and from 29 Dec 2002 to 18 Jan 2003 (ATIC-2). A comparison of albedo signals in the silicon matri:x in ATIC-1 experiment with simulations performed using the GEANT 3.21 code and the QGSM event generator for nucleus-nucleus interactions is presented.

Zatsepin, V. I.↗
NASA NTRS1990

Close binding of identity and location in visual feature perception

The binding of identity and location information in disjunctive feature search was studied. Ss searched a heterogeneous display for a color or a form target, and reported both target identity and location. To avoid better than chance guessing of target identity (by choosing the target less likely to have been seen), the difficulty of the two targets was equalized adaptively; a mathematical model was used to quantify residual effects. A spatial layout was used that minimized postperceptual errors in reporting location. Results showed strong binding of identity and location perception. After correction for guessing, no perception of identity without location was found. A weak trend was found for accurate perception of target location without identity. We propose that activated features generate attention-calling "interrupt" signals, specifying only location; attention then retrieves the properties at that location.

Orientation↗
NASA NTRS2010

Pharmacological Issues for Astronauts

Medication-induced side effects, called untoward effects by pharmacologists, can be a problem with any medication. Few therapies are perfectly specific for the desired physiological activity; rather they act on multiple biological targets and result in multiple physiological effects. There are several strategies that are employed to prevent, alleviate or counteract medication-induced side effects. The administered dose may be optimized to the lowest possible amount that provides the desired therapeutic effect, with the expectation that untoward effects will be minimized by a lower dose. Empirical trials of different therapies for a particular medical problem may be used in the hopes of finding a drug with minimal side effects for a particular patient, or at least of finding a set of side effects that the patient considers tolerable. If these two strategies have been exhausted, it may be possible to administer another medication to block or ameliorate side effects. A recent search of published scientific literature has revealed that there are medications used in spaceflight that seem to be associated with a significant number of reports of untoward effects. To prevent future medical problems and to improve the well-being and productivity of crew members, it would be best to eliminate (or at least reduce) untoward effects. Reports from the literature will be examined, with the aim of identifying a strategy for reducing untoward effects.

Wotring, Virginia E.↗
NASA NTRS2010

Verification Challenges of Dynamic Testing of Space Flight Hardware

The Six Degree-of-Freedom Dynamic Test System (SDTS) is a test facility at the National Aeronautics and Space Administration (NASA) Johnson Space Center in Houston, Texas for performing dynamic verification of space structures and hardware. Some examples of past and current tests include the verification of on-orbit robotic inspection systems, space vehicle assembly procedures and docking/berthing systems. The facility is able to integrate a dynamic simulation of on-orbit spacecraft mating or demating using flight-like mechanical interface hardware. A force moment sensor is utilized for input to the simulation during the contact phase, thus simulating the contact dynamics. While the verification of flight hardware presents many unique challenges, one particular area of interest is with respect to the use of external measurement systems to ensure accurate feedback of dynamic contact. There are many commercial off-the-shelf (COTS) measurement systems available on the market, and the test facility measurement systems have evolved over time to include two separate COTS systems. The first system incorporates infra-red sensing cameras, while the second system employs a laser interferometer to determine position and orientation data. The specific technical challenges with the measurement systems in a large dynamic environment include changing thermal and humidity levels, operational area and measurement volume, dynamic tracking, and data synchronization. The facility is located in an expansive high-bay area that is occasionally exposed to outside temperature when large retractable doors at each end of the building are opened. The laser interferometer system, in particular, is vulnerable to the environmental changes in the building. The operational area of the test facility itself is sizeable, ranging from seven meters wide and five meters deep to as much as seven meters high. Both facility measurement systems have desirable measurement volumes and the accuracies vary within the respective volumes. In addition, because this is a dynamic facility with a moving test bed, direct line-of-sight may not be available at all times between the measurement sensors and the tracking targets. Finally, the feedback data from the active test bed along with the two external measurement systems must be synchronized to allow for data correlation. To ensure the desired accuracy and resolution of these systems, calibration of the systems must be performed regularly. New innovations in sensor technology itself are periodically incorporated into the facility s overall measurement scheme. In addressing the challenges of the measurement systems, the facility is able to provide essential position and orientation data to verify the dynamic performance of space flight hardware.

Winnitoy, Susan↗
NASA NTRS2003

Coordination of Lower Limb Joints During Locomotion: The Effects of Vestibulo-Ocular Reflex Adaptation

Controlling locomotion while maintaining a stable gaze requires precise coordination between several, interdependent full-body sensorimotor subsystems (Bloomberg and Mulavara, 2003; McDonald, et al., 1997). The overall goal of this study is to determine how this full-body gaze stabilization system responds to adaptive changes in vestibuloocular reflex (VOR) function. Locomotion involves cyclical physical interactions (impacts) with the environment. Hence, focusing on a target and maintaining visual acuity during this activity may require mechanisms to manage the energy flow, so it does not disrupt the visual and vestibular sensory information processing that stabilizes gaze. It has been shown that increasing the difficulty of a gaze task (reading numbers on a screen as opposed to simply focusing on a central dot pattern) resulted in an increase in the amount of knee flexion movement during the critical phase immediately following the heel strike event (Mulavara and Bloomberg, 2003). The increase in knee flexion during the stance phase of the gait cycle has been suggested to function as a shock absorbing mechanism associated with the rapid weight transfer from the trailing to the leading leg during walking. To understand this full-body coordination, the relative contributions of each component and the resulting effects should be assessed. In this study, we hypothesized that VOR adaptation would result in a reorganization of the lower limb joint coordination during treadmill walking in a manner to facilitate the gaze stabilization task and preserve locomotor function.

Miller, Chris↗
NASA NTRS2011

NASA Tech Briefs, April 2011

Topics covered include: Amperometric Solid Electrolyte Oxygen Microsensors with Easy Batch Fabrication; Two-Axis Direct Fluid Shear Stress Sensor for Aerodynamic Applications; Target Assembly to Check Boresight Alignment of Active Sensors; Virtual Sensor Test Instrumentation; Evaluation of the Reflection Coefficient of Microstrip Elements for Reflectarray Antennas; Miniaturized Ka-Band Dual-Channel Radar; Continuous-Integration Laser Energy Lidar Monitor; Miniaturized Airborne Imaging Central Server System; Radiation-Tolerant, SpaceWire-Compatible Switching Fabric; Small Microprocessor for ASIC or FPGA Implementation; Source-Coupled, N-Channel, JFET-Based Digital Logic Gate Structure Using Resistive Level Shifters; High-Voltage-Input Level Translator Using Standard CMOS; Monitoring Digital Closed-Loop Feedback Systems; MASCOT - MATLAB Stability and Control Toolbox; MIRO Continuum Calibration for Asteroid Mode; GOATS Image Projection Component; Coded Modulation in C and MATLAB; Low-Dead-Volume Inlet for Vacuum Chamber; Thermal Control Method for High-Current Wire Bundles by Injecting a Thermally Conductive Filler; Method for Selective Cleaning of Mold Release from Composite Honeycomb Surfaces; Infrared-Bolometer Arrays with Reflective Backshorts; Commercialization of LARC (trade mark) -SI Polyimide Technology; Novel Low-Density Ablators Containing Hyperbranched Poly(azomethine)s; Carbon Nanotubes on Titanium Substrates for Stray Light Suppression; Monolithic, High-Speed Fiber-Optic Switching Array for Lidar; Grid-Tied Photovoltaic Power System; Spectroelectrochemical Instrument Measures TOC; A Miniaturized Video System for Monitoring Drosophila Behavior; Hydrofocusing Bioreactor Produces Anti-Cancer Alkaloids; Creep Measurement Video Extensometer; Radius of Curvature Measurement of Large Optics Using Interferometry and Laser Tracker n-B-pi-p Superlattice Infrared Detector; Safe Onboard Guidance and Control Under Probabilistic Uncertainty; General Tool for Evaluating High-Contrast Coronagraphic Telescope Performance Error Budgets; Hidden Statistics of Schroedinger Equation; Optimal Padding for the Two-Dimensional Fast Fourier Transform; Spatial Query for Planetary Data; Higher Order Mode Coupling in Feed Waveguide of a Planar Slot Array Antenna; Evolutionary Computational Methods for Identifying Emergent Behavior in Autonomous Systems; Sampling Theorem in Terms of the Bandwidth and Sampling Interval; Meteoroid/Orbital Debris Shield Engineering Development Practice and Procedure; Self-Balancing, Optical-Center-Pivot, Fast-Steering Mirror; Wireless Orbiter Hang-Angle Inclinometer System; and Internal Electrostatic Discharge Monitor - IESDM.

Source record↗
NASA NTRS2014

Non-Cooled Power System for Venus Lander

The Planetary Science Decadal Survey of 2013-2022 stated that the exploration of Venus is of significant interest. Studying the seismic activity of the planet is of particular importance because the findings can be compared to the seismic activity of Earth. Further, the geological and atmospheric properties of Venus will shed light into the past and future of Earth. This paper presents a radioisotope power system (RPS) design for a small low-power Venus lander. The feasibility of the new power system is then compared to that of primary batteries. A requirement for the power source system is to avoid moving parts in order to not interfere with the primary objective of the mission - to collect data about the seismic activity of Venus using a seismometer. The target mission duration of the lander is 117 days, a significant leap from Venera 13, the longest-lived lander on the surface of Venus, which survived for 2 hours. One major assumption for this mission design is that the power source system will not provide cooling to the other components of the lander. This assumption is based on high-temperature electronics technology that will enable the electronics and components of the lander to operate at Venus surface temperature. For the proposed RPS, a customized General Purpose Heat Source Radioisotope Thermoelectric Generator (GPHSRTG) is designed and analyzed. The GPHS-RTG is chosen primarily because it has no moving parts and it is capable of operating for long duration missions on the order of years. This power system is modeled as a spherical structure for a fundamental thermal analysis. The total mass and electrical output of the system are calculated to be 24 kilograms and 26 Watts, respectively. An alternative design for a battery-based power system uses Sodium Sulfur batteries. To deliver a similar electrical output for 117 days, the battery mass is calculated to be 234 kilograms. Reducing mission duration or power required will reduce the required battery mass. Finally, the advantages and disadvantages of both power systems with regard to science return, risk, and cost are briefly compared. The design of the radioisotope power system is considerably riskier because it is novel and would require additional years of further refinement, manufacturing, safety analysis, and testing that the primary batteries do not need. However, the lifetime of the radioisotope power system makes its science return more promising.

planetary↗
NASA NTRS2011

Comet Ephemerides for the EPOXI and Stardust-NExT Flybys

The recently successful flybys of Comet 103P/Hartley 2 by the Deep Impact spacecraft and Comet 9P/Tempel 1 by the Stardust spacecraft each presented different challenges from the perspective of comet ephemeris prediction and spacecraft targeting. Hartley 2 is a small, highly active comet, with nongravitational accelerations that proved very difficult to model, requiring some amount of "cometchasing" by the spacecraft navigators. In contrast, Tempel 1 is a far larger and less active comet. It showed very stable ephemeris behavior and at flyby was within 1-sigma of predictions issued more than a year prior to encounter. This happenstance was fortuitous because the Stardust spacecraft had very little fuel margin available for comet ephemeris errors.

non-gravitational accelerations↗
NASA NTRS2016

Soil Moisture Active Passive Mission L4_C Data Product Assessment (Version 2 Validated Release)

The SMAP satellite was successfully launched January 31st 2015, and began acquiring Earth observation data following in-orbit sensor calibration. Global data products derived from the SMAP L-band microwave measurements include Level 1 calibrated and geolocated radiometric brightness temperatures, Level 23 surface soil moisture and freezethaw geophysical retrievals mapped to a fixed Earth grid, and model enhanced Level 4 data products for surface to root zone soil moisture and terrestrial carbon (CO2) fluxes. The post-launch SMAP mission CalVal Phase had two primary objectives for each science product team: 1) calibrate, verify, and improve the performance of the science algorithms, and 2) validate accuracies of the science data products as specified in the L1 science requirements. This report provides analysis and assessment of the SMAP Level 4 Carbon (L4_C) product pertaining to the validated release. The L4_C validated product release effectively replaces an earlier L4_C beta-product release (Kimball et al. 2015). The validated release described in this report incorporates a longer data record and benefits from algorithm and CalVal refinements acquired during the SMAP post-launch CalVal intensive period. The SMAP L4_C algorithms utilize a terrestrial carbon flux model informed by SMAP soil moisture inputs along with optical remote sensing (e.g. MODIS) vegetation indices and other ancillary biophysical data to estimate global daily net ecosystem CO2 exchange (NEE) and component carbon fluxes for vegetation gross primary production (GPP) and ecosystem respiration (Reco). Other L4_C product elements include surface (10 cm depth) soil organic carbon (SOC) stocks and associated environmental constraints to these processes, including soil moisture and landscape freeze/thaw (FT) controls on GPP and respiration (Kimball et al. 2012). The L4_C product encapsulates SMAP carbon cycle science objectives by: 1) providing a direct link between terrestrial carbon fluxes and underlying FT and soil moisture constraints to these processes, 2) documenting primary connections between terrestrial water, energy and carbon cycles, and 3) improving understanding of terrestrial carbon sink activity in northern ecosystems. There are no L1 science requirements for the L4_C product; however self-imposed requirements have been established focusing on NEE as the primary product field for validation, and on demonstrating L4_C accuracy and success in meeting product science requirements (Jackson et al. 2012). The other L4_C product fields also have strong utility for carbon science applications; however, analysis of these other fields is considered secondary relative to primary validation activities focusing on NEE. The L4_C targeted accuracy requirements are to meet or exceed a mean unbiased accuracy (ubRMSE) for NEE of 1.6 g C/sq m/d or 30 g C/sq m/yr, emphasizing northern (45N) boreal and arctic ecosystems; this is similar to the estimated accuracy level of in situ tower eddy covariance measurement-based observations (Baldocchi 2008).

Cal/Val↗
NASA NTRS2016

Development of an Airborne Triple-Pulse 2-Micron Integrated Path Differential Absorption Lidar (IPDA) for Simultaneous Airborne Column Measurements of Carbon Dioxide and Water Vapor in the Atmosphere

This presentation will provide status and details of an airborne 2-micron triple-pulse integrated path differential absorption (IPDA) lidar being developed at NASA Langley Research Center with support from NASA ESTO Instrument Incubator Program. The development of this active optical remote sensing IPDA instrument is targeted for measuring both atmospheric carbon dioxide and water vapor in the atmosphere from an airborne platform. This presentation will focus on the advancement of the 2-micron triple-pulse IPDA lidar development. Updates on the state-of-the-art triple-pulse laser transmitter will be presented including the status of seed laser locking, wavelength control, receiver and detector upgrades, laser packaging and lidar integration. Future plan for IPDA lidar system for ground integration, testing and flight validation will also be presented.

Singh, Upendra N.↗
NASA NTRS2016

Design Considerations for Spacecraft Operations During Uncrewed Dormant Phases of Human Exploration Missions

NASA is transforming human spaceflight. The Agency is shifting from an exploration-based program with human activities in low Earth orbit (LEO) and targeted robotic missions in deep space to a more sustainable and integrated pioneering approach. However, pioneering space involves daunting technical challenges of transportation, maintaining health, and enabling crew productivity for long durations in remote, hostile, and alien environments. Subject matter experts from NASA's Human Exploration and Operations Mission Directorate (HEOMD) are currently studying a human exploration campaign that involves deployment of assets for planetary exploration. This study, called the Evolvable Mars Campaign (EMC) study, explores options with solar electric propulsion as a central component of the transportation architecture. This particular in-space transportation option often results in long duration transit to destinations. The EMC study is also investigating deployed human rated systems like landers, habitats, rovers, power systems and ISRU system to the surface of Mars, which also will involve long dormant periods when these systems are staged on the surface. In order to enable the EMC architecture, campaign and element design leads along with system and capability development experts from HEOMD's System Maturation Team (SMT) have identified additional capabilities, systems and operation modes that will sustain these systems especially during these dormant phases of the mission. Dormancy is defined by the absence of crew and relative inactivity of the systems. For EMC missions, dormant periods could range from several months to several years. Two aspects of uncrewed dormant operations are considered herein: (1) the vehicle systems that are placed in a dormant state and (2) the autonomous vehicle systems and robotic capabilities that monitor, maintain, and repair the vehicle and systems. This paper describes the mission stages of dormancy operations, phases of dormant operations, and critical system capabilities that are needed for dormant operations. This paper will compare dormancy operations of past robotic missions to identify lessons that can be applied to planned human exploration missions. Finally, this paper will also identify future work and analysis planned to assess system performance metrics and integrated system operations.

Williams-Byrd, Julie↗
NASA NTRS2016

Airborne Lidar for Simultaneous Measurement of Column CO2 and Water Vapor in the Atmosphere

The 2-micron wavelength region is suitable for atmospheric carbon dioxide (CO2) measurements due to the existence of distinct absorption feathers for the gas at this particular wavelength. For more than 20 years, researchers at NASA Langley Research Center (LaRC) have developed several high-energy and high repetition rate 2-micron pulsed lasers. This paper will provide status and details of an airborne 2-micron triple-pulse integrated path differential absorption (IPDA) lidar. The development of this active optical remote sensing IPDA instrument is targeted for measuring both CO2 and water vapor (H2O) in the atmosphere from an airborne platform. This presentation will focus on the advancement of the 2-micron triple-pulse IPDA lidar development. Updates on the state-of-the-art triple-pulse laser transmitter will be presented including the status of seed laser locking, wavelength control, receiver telescope, detection system and data acquisition. Future plans for the IPDA lidar system for ground integration, testing and flight validation will also be presented.

Singh, Upendra N.↗
NASA NTRS2017

Scenario Development Process at the Vertical Motion Simulator

There has been a significant effort within the simulation community to standardize many aspects of flight simulation. More recently, an effort has begun to develop a formal scenario definition language for aviation. A working group within the AIAA Modeling and Simulation Technical Committee has been created to develop a standard aviation scenario definition language, though much of the initial effort has been tailored to training simulators. Research and development (R&D) simulators, like the Vertical Motion Simulator (VMS), and training simulators have different missions and thus have different scenario requirements. The purpose of this paper is to highlight some of the unique tasks and scenario elements used at the VMS so they may be captured by scenario standardization efforts. The VMS most often performs handling qualities studies and transfer of training studies. Three representative handling qualities simulation studies and two transfer of training simulation studies are described in this paper. Unique scenario elements discussed in this paper included special out-the-window (OTW) targets and environmental conditions, motion system parameters, active inceptor parameters, and configurable vehicle math model parameters.

Vertical Motion Simulator↗
NASA NTRS2018

Overview of MSFC Additive Electronics Capabilities

Focus: Marshall seeks to support the Agency in the development of next generation printed electronics technologies for living and working in space, with emphasis on enhanced electronics manufacturing processes and capabilities development on the ground and in-space. Near-Term: Human Habitation Elements and Life Support Systems - pursuing integrated flexible wearable air, water, vital monitoring solutions for next generation printed technologies; Complete startup printing technology demonstrations which prove basic processes and establish ISM (In-Space Manufacturing) infrastructure needed for future applications including metals based manufacturing. Medium Term: Target low-cost research and demonstration activities that support multi-material additive manufacturing, more sophisticated parts production, printed electronics and ISM; Maturation and flight demonstration of printed propulsion system components, with emphasis on infusion into small-spacecraft-based missions. Long-Term: Evolve systems capabilities to be supportive of destination (lunar or Mars) resources and requirements, increase autonomy in systems and utilize in-situ resources towards manufacturing; Support development of self-replicable systems and their infusion into future spacecraft and missions.

MacLeod, Todd C.↗