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At least 631 records · Page 35

Presenting Model-Based Systems Engineering Information to Non-Modelers

NASA’s Human Research Program’s (HRP) Exploration Medical Capability (ExMC) Element adopted Systems Engineering (SE) principles and Model Based Systems Engineering (MBSE) tools to capture the system functions, system architecture, requirements, interfaces, and clinical capabilities for a future exploration medical system. There are many different stakeholders who may use the information in the model: systems engineers, clinicians (physicians, nurses, and pharmacists), scientists, and program managers. Many of these individuals do not have access to MBSE modeling tools or have never used these tools. Many of these individuals (clinicians, scientists, even program managers) may have no experience with SE in general let alone interpreting a systems model. The challenge faced by ExMC was how to present the content in the model to non-modelers in a way they could understand with limited to no training in MBSE or the Systems Modeling Language (SysML) without using the modeling tool. Therefore, from the model, ExMC created an HTML report that is accessible to anyone with a browser. When creating the HTML report, the ExMC SE team talked to stakeholders and received their feedback on what content they wanted and how to display this content. Factoring in feedback, the report arranges the content in a way that not only directs readers through the SE process taken to derive the requirements, but also helps them to understand the fundamental steps in an SE approach. The report includes links to source information (i.e., NASA documentation that describes levels of care) and other SE deliverables (e.g., Concept of Operations). These links were provided to aid in the understanding of how the team created this content through a methodical SE approach. This paper outlines the process used to develop the model, the data chosen to share with stakeholders, many of the model elements used in the report, the review process stakeholders followed, the comments received from the stakeholders, and the lessons ExMC learned through producing this HTML report.1Trade names and trademarks are used in this report for identification only. Their usage does not constitute an official endorsement, either expressed or implied, by the National Aeronautics and Space Administration.

Jeffrey R. Cohen↗

Presenting Model-Based Systems Engineering Information to Non-Modelers

NASA’s Human Research Program’s (HRP) Exploration Medical Capability (ExMC) Element adopted Systems Engineering (SE) principles and Model Based Systems Engineering (MBSE) tools to capture the system functions, system architecture, requirements, interfaces, and clinical capabilities for a future exploration medical system. There are many different stakeholders who may use the information in the model: systems engineers, clinicians (physicians, nurses, and pharmacists), scientists, and program managers. Many of these individuals do not have access to MBSE modeling tools or have never used these tools. Many of these individuals (clinicians, scientists, even program managers) may have no experience with SE in general let alone interpreting a systems model. The challenge faced by ExMC was how to present the content in the model to non-modelers in a way they could understand with limited to no training in MBSE or the Systems Modeling Language (SysML) without using the modeling tool. Therefore, from the model, ExMC created an HTML report that is accessible to anyone with a browser. When creating the HTML report, the ExMC SE team talked to stakeholders and received their feedback on what content they wanted and how to display this content. Factoring in feedback, the report arranges the content in a way that not only directs readers through the SE process taken to derive the requirements, but also helps them to understand the fundamental steps in an SE approach. The report includes links to source information (i.e., NASA documentation that describes levels of care) and other SE deliverables (e.g., Concept of Operations). These links were provided to aid in the understanding of how the team created this content through methodical SE approach. This paper outlines the process used to develop the model, the data chosen to share with stakeholders, many of the model elements used in the report, the review process stakeholders followed, the comments received from the stakeholders, and the lessons ExMC learned through producing this HTML report.

Jeffrey R. Cohen↗

NO x adsorption with CO and C 2 H 4 on Pd/SSZ-13: Experiments and modeling

A transient monolith model containing microkinetic schemes for NO uptake and release over Pd/SSZ-13 without and with reductants CO or C2H4 is presented. The scheme involves three cationic Pd species (Z – [PdOH] + , Z – Pd 2+ Z – , Z – Pd + ) as the active sites during uptake of NO, CO and C 2 H 4 , and their desorption and conversion at higher temperature. Kinetic parameters are estimated through a combination of density functional theory (DFT) estimates and a fit of uptake, desorption and conversion data. The tuned model is validated at different uptake temperatures, ramp rates, and flowrates. A “degree of uptake control” parameter is defined that helps to identify the step(s) that are uptake controlling. The model helps to interpret the data features and is used to identify operating conditions to meet application-relevant performance metrics, including NO trapping efficiency and NO release temperature. Furthermore, the model demonstrates higher NO uptake on Pd/SSZ-13 compared to Pd/ZSM-5.

42 ENGINEERING↗

Chemical kinetic models for combustion of hydrocarbons and formation of nitric oxide

The formation of nitrogen oxides NOx during combustion of methane, propane, and a jet fuel, JP-4, was investigated in a jet stirred combustor. The results of the experiments were interpreted using reaction models in which the nitric oxide (NO) forming reactions were coupled to the appropriate hydrocarbon combustion reaction mechanisms. Comparison between the experimental data and the model predictions reveals that the CH + N2 reaction process has a significant effect on NO formation especially in stoichiometric and fuel rich mixtures. Reaction models were assembled that predicted nitric oxide levels that were in reasonable agreement with the jet stirred combustor data and with data obtained from a high pressure (5.9 atm (0.6 MPa)), prevaporized, premixed, flame tube type combustor. The results also suggested that the behavior of hydrocarbon mixtures, like JP-4, may not be significantly different from that of pure hydrocarbons. Application of the propane combustion and nitric oxide formation model to the analysis of NOx emission data reported for various aircraft gas turbines showed the contribution of the various nitric oxide forming processes to the total NOx formed.

Jachimowski, C. J.↗

Tropospheric chemical models

The differences in atmospheric composition over the globe and the short- and long-term variations in this composition are the net effect of several atmospheric and biospheric processes: biospheric emissions, atmospheric circulation, atmospheric chemical transformations and finally deposition back to the surface. Accurate and realistic atmospheric chemistry and circulation models are essential to interpret the observed global distributions and trends of atmospheric species in terms of these underlying processes. Comparisons between model predictions and observations test current understanding of these processes and models used in conjunction with inverse methods allow deductions of the rates of these processes from the observations. With the planned inclusion of at least CO and CH4 observations on the Earth Observing System (EOS) satellites, together with the large global data set expected from in situ observations under the International Global Atmospheric Chemistry (IGAC) Project, the further development of global three-dimensional high-resolution atmospheric chemistry and circulation models in order to interpret this new data is a high-priority endeavor.

Prinn, R. G.↗

Nonlinear aerodynamic modeling using multivariate orthogonal functions

A technique was developed for global modeling of nonlinear aerodynamic coefficients using multivariate orthogonal functions based on the data. Each orthogonal function retained in the model was decomposed into an expansion of ordinary polynomials in the independent variables, so that the final model could be interpreted as selectively retained terms from a multivariable power series expansion. A predicted squared-error metric was used to determine the orthogonal functions to be retained in the model; analytical derivatives were easily computed. The approach was demonstrated on the Z-body axis aerodynamic force coefficient (Cz) wind tunnel data for an F-18 research vehicle which came from a tabular wind tunnel and covered the entire subsonic flight envelope. For a realistic case, the analytical model predicted experimental values of Cz very well. The modeling technique is shown to be capable of generating a compact, global analytical representation of nonlinear aerodynamics. The polynomial model has good predictive capability, global validity, and analytical differentiability.

Morelli, Eugene A.↗

Search for new physics in multijet events with at least one photon and large missing transverse momentum in proton-proton collisions at 13 TeV

A search for new physics in final states consisting of at least one photon, multiple jets, and large missing transverse momentum is presented, using proton-proton collision events at a center-of-mass energy of 13 TeV. The data correspond to an integrated luminosity of 137 fb$^{−1}$, recorded by the CMS experiment at the CERN LHC from 2016 to 2018. The events are divided into mutually exclusive bins characterized by the missing transverse momentum, the number of jets, the number of b-tagged jets, and jets consistent with the presence of hadronically decaying W, Z, or Higgs bosons. The observed data are found to be consistent with the prediction from standard model processes. The results are interpreted in the context of simplified models of pair production of supersymmetric particles via strong and electroweak interactions. Depending on the details of the signal models, gluinos and squarks of masses up to 2.35 and 1.43 TeV, respectively, and electroweakinos of masses up to 1.23 TeV are excluded at 95% confidence level.[graphic not available: see fulltext]

72 PHYSICS OF ELEMENTARY PARTICLES AND FIELDS↗

Search for high-mass resonances decaying to a jet and a Lorentz-boosted resonance in proton-proton collisions at s = 13 TeV

A search is reported for high-mass hadronic resonances that decay to a parton and a Lorentz-boosted resonance, which in turn decays into a pair of partons. The search is based on data collected with the CMS detector at the LHC in proton-proton collisions at $\sqrt{s}$ = 13 TeV, corresponding to an integrated luminosity of 138 fb$^{-1}$. The boosted resonance is reconstructed as a single wide jet with substructure consistent with a two-body decay. The high-mass resonance is thus considered as a dijet system. The jet substructure information and the kinematic properties of cascade resonance decays are exploited to disentangle the signal from the large quantum chromodynamics multijet background. The dijet mass spectrum is analyzed for the presence of new high-mass resonances, and is found to be consistent with the standard model background predictions. Results are interpreted in a warped extra dimension model where the high-mass resonance is a Kaluza-Klein gluon, the boosted resonance is a radion, and the final state partons are all gluons. Limits on the production cross section are set as a function of the Kaluza-Klein gluon and radion masses. These limits exclude at 95% confidence level models with Kaluza-Klein gluon masses in the range from 2.0 to 4.3 TeV and radion masses in the range from 0.20 to 0.74 TeV. By exploring a novel experimental signature, the observed limits on the Kaluza-Klein gluon mass are extended by up to about 1 TeV compared to previous searches.

72 PHYSICS OF ELEMENTARY PARTICLES AND FIELDS↗

Caltech Lab Experiments and the Insights They Provide Into Solar Corona Phenomena

A comprehensive overview of two decades of Caltech experiments relevant to solar corona physics is presented. The extent to which the experiments scale to the solar corona, the basic configurations and operation, and the importance of the magnetic force J × B common to all the experiments is discussed. Summaries are given of the various configurations used, the main observations, and interpretations of these observations, including new models developed to provide these interpretations. Topics include observations and explanations for flux rope self-collimation, axial flows along flux ropes, eruption of arched flux ropes, strapping magnetic fields that inhibit eruption, the torus instability, and effects such as X-ray emission of a kink-driven secondary Rayleigh-Taylor instability.

70 PLASMA PHYSICS AND FUSION TECHNOLOGY↗

Joint Modeling of Quasar Variability and Accretion Disk Reprocessing Using Latent Stochastic Differential Equations

Quasars are bright active galactic nuclei powered by the accretion of matter around supermassive black holes at the center of galaxies. Their stochastic brightness variability depends on the physical properties of the accretion disk and black hole. The upcoming Rubin Observatory Legacy Survey of Space and Time (LSST) is expected to observe tens of millions of quasars, so there is a need for efficient techniques like machine learning that can handle the large volume of data. Quasar variability is believed to be driven by an X-ray corona, which is reprocessed by the accretion disk and emitted as UV/optical variability. We are the first to introduce an auto-differentiable simulation of the accretion disk and reprocessing. We use the simulation as a direct component of our neural network to jointly model the driving variability and reprocessing, trained with supervised learning on simulated LSST-like 10 yr quasar light curves. We encode the light curves using a transformer encoder, and the driving variability is reconstructed using latent stochastic differential equations, a physically motivated generative deep learning method that can model continuous-time stochastic dynamics. By embedding the physical processes of the driving signal and reprocessing into our network, we achieve a model that is more robust and interpretable. We demonstrate that our model outperforms a Gaussian process regression baseline and can infer accretion disk parameters and time delays between wave bands, even for out-of-distribution driving signals. Our approach provides a powerful framework that can be adapted to solve other inverse problems in multivariate time series.

Fagin, Joshua [City Univ. of New York (CUNY), NY (↗

Evaluation of a composite mobile holographic nondestructive test system

A simplified theoretical model for the interpretation of the double-exposure holographic interference fringe loci due to the general three-dimensional displacements was derived for the specific composite mobile holographic nondestructive test system. The model, representing a good approximation to a more tedious theoretical result, predicts that a combination of in-plane and out-of-plane displacements of the surface will produce concentric circular-shaped fringe patterns with locations of their center affected by the displacements. Appropriate experiments were designed and carried out for the test of the validity of the theory. These experiments include the taking of double-exposure holograms of in-plane translations and combined in-plane and out-of-plane translations. The simplified model agreed quite well with the experimental results. Experimentally observed effects due to the curvature of the test plate and the variations of the angles of incidence of the laser light suggest that in order for the simplified model to be able to predict the test results more accurately, incidence and reflection of the laser light should be chosen as nearly perpendicular to the surface of the tested object as possible.

Liu, H. K.↗

From minimum-viable-products to full models: a step-wise development of diagnostic forward models in support of design, analysis and modelling on the ST40 tokamak

Like most magnetic confined fusion experiments, the ST40 tokamak started off with a small subset of diagnostics and gradually increased the diagnostic set to include more complex and comprehensive systems. To make the most of each operational phase, forward models of various diagnostics are used and developed to aid design, provide consistency-checks during commissioning, test analysis methods, and build workflows to constrain high-level parameters to inform interpretation, theory and modelling. For new models and new analysis workflows, minimum-viable-products are released early, and their complexity is increased in a step-wise manner, facilitating the support of all programme phases on multiple parallel applications, while enabling learning opportunities and feedback loops. In this contribution we review the philosophy, scope and architecture of the framework under development. We discuss the details of some forward models, with examples on how they are used to aid diagnostic design, to investigate analysis methodologies through synthetic data, and how they are embedded in experimental analysis workflows. We compare previously published experimental results with new, more advanced analysis workflows employing more recent, detailed models and new diagnostic data, providing confirmation of the published material from the 2021–22 experimental campaign.

integrated data analysis↗

Theoretical models of polar-cap convection under the influence of a northward interplanetary magnetic field

The unexpected patterns of high-latitude auroral luminosity and ionospheric convection that are observed when the interplanetary magnetic field (IMF) has a northward orientation have inspired a variety of theoretical interpretations. The existing models, all referring to steady-state conditions, can be classified according to the topology of the polar magnetic field lines and of the polar-cap convection streamlines. The classes of model include: (1) a closed magnetosphere model, (2) a conventional open model with a distorted, but topologically unchanged, polar-cap boundary, (3) a conventional open model with distorted, but topologically unchanged, polar-cap convection cells, (4) a modified open model with 'lobe convection cells' contained wholly on open magnetic-field lines, and (5) a modified open model with a bifurcated polar cap. The third and fourth types require significant regions of sunward flow on open polar-cap field lines, a concept that presents serious theoretical difficulties. The other three types appear equally viable from a theoretical point of view, and the comparison against observations is an ongoing enterprise. Outstanding theoretical questions include (a) how do observed structures in the polar ionosphere map along magnetic field lines into the magnetosphere?, (b) what is the mechanism that drives the observed sunward convection at highest latitudes on the day side?, and (c) what role does time dependence play in the observed phenomena?

Hill, T. W.↗

Mantle Plume Magmatism in Elysium Planitia as Constrained by InSight Seismic Observations

Based on cratering statistics, there has been active volcanism in the last 100 Ma and possibly the last 1 to 10 Ma in both central Elysium Planitia and in the Cerberus Fossae region of south-eastern Elysium. Seismic measurements by the InSight mission show a strong concentration of seismicity in Cerberus Fossae which are interpreted as due to magma transport along dike systems. Together, these observations strongly support the existence of geologically recent and possibly of currently active magmatism in Elysium. InSight seismic observations were also used to construct seismic velocity models for the martian mantle. These models are effectively a regional aver-age of the seismic velocity structure for the Elysium region, where both the InSight lander and most of the measured seismic events are located. These seismic velocity models have been interpreted in terms of the lithospheric thickness and mantle potential temperature. Khan et al. found a lithospheric thickness of 400 to 600 km and a mantle potential temperature of 1325 to 1425 °C. Durán et al. found a lithospheric thickness of ~450 km and a mantle potential tempera-ture of 1375-1475 °C. Drilleau et al. found a thermal lithosphere of 420-660 km and a mantle potential temperature of 1380-1560 °C. In this study, we combine these InSight seismic observations with finite element mantle plume magma production models to place new constraints on the properties of the mantle beneath Elysium Planitia.

Walter S Kiefer↗

L-VISP: LSTM Visualization for Interpretable Symptom Prediction in Patient Cohorts

Symptom modelling in head and neck cancer is challenged by the complexity of heterogeneous patient data, leading to an interest in deep learning approaches. Although Long Short-Term Memory Networks (LSTMs) have shown great results in patient risk prediction, their low interpretability requires data modellers to collaborate with clinical experts to validate the results. We present L-VISP, a human–machine solution that uses visual analytics for LSTM modelling in clinical research. L-VISP uses custom visual encodings to make multiple LSTM variants interpretable, supporting a full range of analysis, from understanding model operations and evaluating performance to interpreting results in a clinical context. We evaluate L-VISP with data modellers and a clinical oncologist and present the takeaways from this multidisciplinary collaboration.

LSTM modeling↗

Beginner's Guide to Understanding Power System Model Results for Long-Term Resource Plans

This presentation summarizes a recently published beginner's guide for understanding power system model results for long-term resource plans. This guide is designed to improve decision-making in the electricity planning process by strengthening dialogue between system planners and relevant stakeholders. It focuses on interpreting scenario results generated by power system planning models. These results are often used to inform integrated resource plans, which are long-term plans for a utility to meet future electricity requirements. Whether you are a state utility commissioner, commission staff, part of a state energy office, an intervenor in the planning process, or another stakeholder, this guide is designed to help you better weigh in on the modeling methods or interpret the model results to improve decision-making. This guide can enhance your understanding to ask the right questions, which can enable better understanding of results and key assumptions, data, and methods.

ENERGY PLANNING, POLICY, AND ECONOMY↗

Deep learning integrates histopathology and proteogenomics at a pan-cancer level

We introduce a pioneering approach that integrates pathology imaging with transcriptomics and proteomics to identify predictive histology features associated with critical clinical outcomes in cancer. We utilize 2,755 H&E-stained histopathological slides from 657 patients across 6 cancer types from CPTAC. Our models effectively recapitulate distinctions readily made by human pathologists: tumor vs. normal (AUROC = 0.995) and tissue-of-origin (AUROC = 0.979). We further investigate predictive power on tasks not normally performed from H&E alone, including TP53 prediction and pathologic stage. Importantly, we describe predictive morphologies not previously utilized in a clinical setting. The incorporation of transcriptomics and proteomics identifies pathway-level signatures and cellular processes driving predictive histology features. Model generalizability and interpretability is confirmed using TCGA. We propose a classification system for these tasks, and suggest potential clinical applications for this integrated human and machine learning approach. A publicly available web-based platform implements these models.

60 APPLIED LIFE SCIENCES↗

Physical properties of Oxia/Lunae Planum and Arabia-type units in the central equatorial region of Mars

Classification and mapping of surficial units in the central equatorial region of Mars Consortium data identified the relatively dark but 'red' materials that cover Lunae Planum and surround the Meridiani materials of Oxia Palus inertia region of Arabia. Oxia Province consists of the regions dominated by the characteristically dark 'red' Oxia materials, but it includes darker streaks and splotches of relatively 'blue' Meridiani materials and brighter 'red' deposits of dust belonging to Eos Province (the bright 'red' border between Oxia and regional Meridiani deposits to the south) and Xanthe Province (the moderately bright 'red' dust deposits in western Chryse Planitia and its vicinity, including the VL-1 landing site). Two Oxia units were recognized: a darker unit present on Lunae Planum and east of Oxia Palus that have intermediate to high inertias. Oxia Province surrounds the extremely low thermal inertia Arabia Province in the east part of the study area, and occurs as isolated patches within Arabia (often including splotches of Meridiani materials within the Oxia patches). Arabia Province's materials have been widely interpreted as unconsolidated dust deposits which are currently forming at this stage of Mars' precessional climate cycle, although the persistence of stable, moderately strong albedo contracts among Arabia materials has not been addressed in those models. A systematic interpretation of Oxia and Arabia Province materials based on currently available remote sensing data is given.

Strickland, Edwin L., III↗