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At least 631 records · Page 35

SU-E-J-160: Comparing the Setup Accuracy of Non-Ionizing Patient Localization Systems with CBCT to Reduce Imaging Dose in Prone Breast Treatments

Purpose: CBCT is the current gold standard to verify prone breast patient setup. We investigated in a phantom if non-ionizing localization systems can replace ionizing localization systems for prone breast treatments. Methods: An anthropomorphic phantom was positioned on a prone breast board. Electromagnetic transponders were attached on the left chest surface. The CT images of the phantom were imported to the treatment planning system. The isocenter was set to the center of the transponders. The positions of the isocenter and transponders transferred to the transponder tracking system. The posterior phantom surface was contoured and exported to the optical surface tracking system. A CBCT was taken for the initial setup alignment on the treatment machine. Using the electromagnetic and optical localization systems, the deviation of the phantom setup from the original CT images was measured. This was compared with the difference between the original CT and kV-CBCT images. Results: For the electromagnetic localization system, the phantom position deviated from the original CT in 1.5 mm, 0.0 mm and 0.5 mm in the anterior-posterior (AP), superior-inferior (SI) and left-right (LR) directions. For the optical localization system, the phantom position deviated from the original CT in 2.0 mm, −2.0 mm and 0.1 mm in the AP, SI and LR directions. For the CBCT, the phantom position deviated from the original CT in 4.0 mm, 1.0 mm and −1.0 mm in the AP, SI and LR directions. The measured values from the non-ionizing localization systems differed from those with the CBCT less than 3.0 mm in all directions. Conclusions: This phantom study showed the feasibility of using a combination of non-ionizing localization systems to achieve a similar setup accuracy as CBCT for prone breast patients. This could potentially eliminate imaging dose. As a next step, we are expanding this study to actual patients. This work has been in part supported by Departmental Research Award RODEPT1-JS001, Department of Radiation Oncology, UC Davis Medical Center.

60 APPLIED LIFE SCIENCES↗

Systematic study of target localization for bioluminescence tomography guided radiation therapy

Purpose: To overcome the limitation of CT/cone-beam CT (CBCT) in guiding radiation for soft tissue targets, the authors developed a spectrally resolved bioluminescence tomography (BLT) system for the small animal radiation research platform. The authors systematically assessed the performance of the BLT system in terms of target localization and the ability to resolve two neighboring sources in simulations, tissue-mimicking phantom, and in vivo environments. Methods: Multispectral measurements acquired in a single projection were used for the BLT reconstruction. The incomplete variables truncated conjugate gradient algorithm with an iterative permissible region shrinking strategy was employed as the optimization scheme to reconstruct source distributions. Simulation studies were conducted for single spherical sources with sizes from 0.5 to 3 mm radius at depth of 3–12 mm. The same configuration was also applied for the double source simulation with source separations varying from 3 to 9 mm. Experiments were performed in a standalone BLT/CBCT system. Two self-illuminated sources with 3 and 4.7 mm separations placed inside a tissue-mimicking phantom were chosen as the test cases. Live mice implanted with single-source at 6 and 9 mm depth, two sources at 3 and 5 mm separation at depth of 5 mm, or three sources in the abdomen were also used to illustrate the localization capability of the BLT system for multiple targets in vivo. Results: For simulation study, approximate 1 mm accuracy can be achieved at localizing center of mass (CoM) for single-source and grouped CoM for double source cases. For the case of 1.5 mm radius source, a common tumor size used in preclinical study, their simulation shows that for all the source separations considered, except for the 3 mm separation at 9 and 12 mm depth, the two neighboring sources can be resolved at depths from 3 to 12 mm. Phantom experiments illustrated that 2D bioluminescence imaging failed to distinguish two sources, but BLT can provide 3D source localization with approximately 1 mm accuracy. The in vivo results are encouraging that 1 and 1.7 mm accuracy can be attained for the single-source case at 6 and 9 mm depth, respectively. For the 2 sources in vivo study, both sources can be distinguished at 3 and 5 mm separations, and approximately 1 mm localization accuracy can also be achieved. Conclusions: This study demonstrated that their multispectral BLT/CBCT system could be potentially applied to localize and resolve multiple sources at wide range of source sizes, depths, and separations. The average accuracy of localizing CoM for single-source and grouped CoM for double sources is approximately 1 mm except deep-seated target. The information provided in this study can be instructive to devise treatment margins for BLT-guided irradiation. These results also suggest that the 3D BLT system could guide radiation for the situation with multiple targets, such as metastatic tumor models.

60 APPLIED LIFE SCIENCES↗

SU-F-I-10: Spatially Local Statistics for Adaptive Image Filtering

Purpose: To facilitate adaptive image filtering operations, addressing spatial variations in both noise and signal. Such issues are prevalent in cone-beam projections, where physical effects such as X-ray scattering result in spatially variant noise, violating common assumptions of homogeneous noise and challenging conventional filtering approaches to signal extraction and noise suppression. Methods: We present a computational mechanism for probing into and quantifying the spatial variance of noise throughout an image. The mechanism builds a pyramid of local statistics at multiple spatial scales; local statistical information at each scale includes (weighted) mean, median, standard deviation, median absolute deviation, as well as histogram or dynamic range after local mean/median shifting. Based on inter-scale differences of local statistics, the spatial scope of distinguishable noise variation is detected in a semi- or un-supervised manner. Additionally, we propose and demonstrate the incorporation of such information in globally parametrized (i.e., non-adaptive) filters, effectively transforming the latter into spatially adaptive filters. The multi-scale mechanism is materialized by efficient algorithms and implemented in parallel CPU/GPU architectures. Results: We demonstrate the impact of local statistics for adaptive image processing and analysis using cone-beam projections of a Catphan phantom, fitted within an annulus to increase X-ray scattering. The effective spatial scope of local statistics calculations is shown to vary throughout the image domain, necessitating multi-scale noise and signal structure analysis. Filtering results with and without spatial filter adaptation are compared visually, illustrating improvements in imaging signal extraction and noise suppression, and in preserving information in low-contrast regions. Conclusion: Local image statistics can be incorporated in filtering operations to equip them with spatial adaptivity to spatial signal/noise variations. An efficient multi-scale computational mechanism is developed to curtail processing latency. Spatially adaptive filtering may impact subsequent processing tasks such as reconstruction and numerical gradient computations for deformable registration. NIH Grant No. R01-184173.

60 APPLIED LIFE SCIENCES↗

Localization of Excitations near a Thin Structured Spacer between Linear and Nonlinear Crystals

It has been shown that localized and semi-localized stationary states exist near a thin structured defect layer between a linear medium and a Kerr nonlinear medium. Localized states are described by a monotonically decreasing amplitude of the field on the both sides of the interface between the media. Semilocalized states are characterized by the field that has the form of a standing wave in the linear medium and decreases monotonically in the nonlinear medium. Kerr media with self-focusing and defocusing are considered. The proposed model is described by a system of the linear and nonlinear Schrödinger equations with a specific potential simulating a thin structured defect layer. It has been shown that localized and semi-localized states exist in different energy ranges in the case of contact of the linear medium with the self-focusing medium. In the case of contact of the linear medium with the defocusing medium, two types of localized and semi-localized states differing in energy and field profile can exist in different energy ranges. In particular cases, expressions for energies of states of these types have been obtained and conditions of their applicability have been indicated.

71 CLASSICAL AND QUANTUM MECHANICS, GENERAL PHYSIC↗

Dynamically Collected Local Density using Low-Cost Lidar and its Application to Traffic Models

This article demonstrates the use of traffic density observations collected dynamically in the vicinity of probe vehicles. Fixed position sensors cannot capture the longitudinal evolution of local traffic density in the corridor. In this research, dynamic traffic density observations were collected in a naturalistic driving setting that was free of any controlled experiment biases. Speed from global positioning system and space headway from a light detection and ranging module was collected on one arterial and one freeway segment, 2 and 4mi long, respectively. The combined data frequency was approximately 3Hz. Space headway was used to estimate the local density and consequently to identify the density of a specific location in a corridor. Besides, driver behavior was characterized using the relationship between instantaneous speed and local density under different regimes of the Wiedemann car-following model. Macroscopic traffic stream models were used to investigate the relationship between dynamically collected instantaneous speed and local density. Using the longitudinal evolution of density, precise local density across the corridor can be obtained along with the leader and follower trajectories. A method to identify driver behavior across density ranges was developed for different facility types using a microscopic relationship between instantaneous speed and local density. Overall driving behavior on the freeway segment can be represented by translating the instantaneous speed and local density relationship to macroscopic stream models.

Engineering↗

THE METALLICITY EVOLUTION OF BLUE COMPACT DWARF GALAXIES FROM THE INTERMEDIATE REDSHIFT TO THE LOCAL UNIVERSE

We present oxygen abundance measurements for 74 blue compact dwarf (BCD) galaxies in the redshift range of [0.2, 0.5] using the strong-line method. The spectra of these objects are taken using Hectospec on the Multiple Mirror Telescope. More than half of these BCDs had dust attenuation corrected using the Balmer decrement method. For comparison, we also selected a sample of 2023 local BCDs from the Sloan Digital Sky Survey (SDSS) database. Based on the local and intermediate-z BCD samples, we investigated the cosmic evolution of the metallicity, star formation rate (SFR), and D{sub n}(4000) index. Compared with local BCDs, the intermediate-z BCDs had a systematically higher R23 ratio but a similar O32 ratio. Interestingly, no significant deviation in the mass–metallicity (MZ) relation was found between the intermediate-z and local BCDs. Besides the metallicity, the intermediate-z BCDs also exhibited an SFR distribution that was consistent with local BCDs, suggesting a weak dependence on redshift. The intermediate-z BCDs seemed to be younger than the local BCDs with lower D{sub n}(4000) index values. The insignificant deviation in the mass–metallicity and mass–SFR relations between intermediate-z and local BCDs indicates that the relations between the global parameters of low-mass compact galaxies may be universal. These results from low-mass compact galaxies could be used to place important observational constraints on galaxy formation and evolution models.

79 ASTRONOMY AND ASTROPHYSICS↗

On the correlation between ‘non-local’ effects and intrinsic rotation reversals in Alcator C-Mod

Contemporary predictive models for heat and particle transport in tokamak plasmas are based on the assumption that local fluxes can be described in terms of local plasma parameters, where electromagnetic drift-wave-type turbulence is driven by local gradients and results in cross-field transport. The question of whether or not transport could be dominated by non-local terms in certain circumstances is essential for our understanding of transport in magnetically confined plasmas, and critical for developing predictive models for future tokamaks, such as ITER. Perturbative transport experiments using cold-pulse injections at low density seem to challenge the local closure of anomalous transport: a rapid temperature increase in the core of the plasma following a sharp edge cooling is widely observed in tokamaks and helical devices. Past work in Ohmic plasmas in Alcator C-Mod and in ECH plasmas in KSTAR found that the temperature inversions disappear at higher densities, above the intrinsic toroidal rotation reversal density. These observations suggested that the so-called 'non-local' heat transport effects were related to the intrinsic rotation reversal, and therefore to changes in momentum transport. In this work, new experiments and analysis at Alcator C-Mod show that intrinsic rotation reversals and disappearance of temperature inversions are not concomitant in Ohmic plasmas at high plasma current and in ICRH L-modes. This new data set shows that the correlation between transient temperature inversions and intrinsic rotation reversals is not universal, suggesting that 'non-local' heat transport and momentum transport effects may be affected by different physical mechanisms.

70 PLASMA PHYSICS AND FUSION TECHNOLOGY↗

Local flow measurements at the inlet spike tip of a Mach 3 supersonic cruise airplane

The flow field at the left inlet spike tip of a YF-12A airplane was examined using at 26 deg included angle conical flow sensor to obtain measurements at free-stream Mach numbers from 1.6 to 3.0. Local flow angularity, Mach number, impact pressure, and mass flow were determined and compared with free-stream values. Local flow changes occurred at the same time as free-stream changes. The local flow usually approached the spike centerline from the upper outboard side because of spike cant and toe-in. Free-stream Mach number influenced the local flow angularity; as Mach number increased above 2.2, local angle of attack increased and local sideslip angle decreased. Local Mach number was generally 3 percent less than free-stream Mach number. Impact-pressure ratio and mass flow ratio increased as free-stream Mach number increased above 2.2, indicating a beneficial forebody compression effect. No degradation of the spike tip instrumentation was observed after more than 40 flights in the high-speed thermal environment encountered by the airplane. The sensor is rugged, simple, and sensitive to small flow changes. It can provide accurate imputs necessary to control an inlet.

Johnson, H. J.↗

Thermal infrared properties of the Martian atmosphere. III - Local dust clouds

Prior to and during the Martian global dust storms in 1977, local dust clouds were identified from thermal observations. Local dust clouds appear up to 40 K cooler than the surrounding region in the daytime and appear warm at night. In contrast to their well-developed and consistent thermal signatures, local dust clouds exhibited little albedo contrast. Multiple observations of the same areas show that local dust clouds form and dissipate in a few days or less, and clouds were observed to move with velocities of from 14 to at least 32 m/sec. Local dust clouds are common along the receding edge of the south polar cap (observed primarily for orbiter imaging) and in the restricted area -10 deg to -30 deg, 80 deg to 125 deg W (observed primarily by the infrared thermal mapper); several of the latter occurred over a ridge in Claritas Fossae, indicating strong topographic control. In their active growing stage, local dust clouds are probably about 8 km high and have relatively abrupt tops. The accumulation of dust from local clouds reached similar levels immediately prior to both global storms, supporting the hypothesis that such dust accumulations are responsible for triggering the global dust storms.

Peterfreund, A. R.↗

Modeling of Instrument Landing System (ILS) localizer signal on runway 25L at Los Angeles International Airport

A joint NASA/FAA flight test has been made to record instrument landing system (ILS) localizer receiver signals for use in mathematically modeling the ILS localizer for future simulation studies and airplane flight tracking tasks. The flight test was conducted on a portion of the ILS localizer installed on runway 25L at the Los Angeles International Airport. The tests covered the range from 10 to 32 n.mi. from the localizer antenna. Precision radar tracking information was compared with the recorded localizer deviation data. Data analysis showed that the ILS signal centerline was offset to the left of runway centerline by 0.071 degrees and that no significant bends existed on the localizer beam. Suggested simulation models for the ILS localizer are formed from a statistical analysis.

Hueschen, Richard M.↗

MHD modeling of magnetotail instability for localized resistivity

We present results of a three-dimensional magnetohydrodynamic (MHD) simulation of magnetotail evolution initiated by a sudden occurrence or increase of spatially localized resistivity as the major expected concequence of some localized microinstability. Because of the absence of a quantitative model, possible variations of resistivity levels with current density, or the reduction thereof, are not incorporated in the present investigation. The emphasis of the study is on an investigation of the changes to the overall evolution brought about by this localization, in particular, on the disruption and diversion of the cross-tail current and the nonlinear evolution of the magnetotail instability. The immediate consequences of the occurrence of the localized resistance and the resulting electric field are a reduction and diversion of the electric current around the region of high resistivity, associated with an increase of B(sub z) ('dipolarization') at the earthward edge and a decrease of B(sub z) at the tailward edge of this region. These effects, however, are localized and do not involve a reduction of the total cross-tail current and hence do not lead to the global development of a 'substorm current wedge,' which includes not only the reduction of the cross-tail current but also the buildup of a global field-aligned current system of 'regional 1' type (toward the Earth on the dawnside and away on the duskside of the tail). Such signatures develop at a later time, as consequences of a three-dimensional tearing instability, which is triggered by the occurrence of the resistivity. These features are found in combination with plasmoid formation and ejection, quite similar to results of earlier simulations with uniform resistivity. Differences are found in the timescale of the evolution, which tends to be shorter for localized resistivity, and in the propagation of the dipolarization effects in the equatorial plane. Whereas for uniform resistivity the temporal increase in B(sub z) tends to propagate tailward, apparently due to a pileup effect in the near-Earth region, an earthward propagation is found for the localized resistivity. This propagation results from an earthward convection of the gradient in B(sub z), which is set up by the reconnection process further tailward.

Hesse, Michael↗

Epsilon Canis Majoris and the ionization of the local cloud

The Lyman continuum radiation from the brightest extreme ultraviolet (EUV) source, the B2 II star epsilon Canis Majoris (Adara), is so intense that it dominates the local stellar EUV radiation field at wavelengths longer than 450 A and therefore sets a lower limit to the ionization of hydrogen in the Local Cloud. Using the EUV (70-730 A) spectrum of epsilon CMa taken with the Extreme Ultraviolet Explorer Satellite (EUVE) and simple models that extrapolate this spectrum to the Lyman edge at 912 A, we have determined the local interstellar hydrogen photionizatin parameter Gamma solely from epsilon CMa to be 1.1 x 10(exp -15)/s. This fiugre is a factor of 7 greater than previous estimates of Gamma calculated for all nearby stars combined (Bruhweiler & Cheng 1988). Using measured values of the density and temperature of neutral interstellar hydrogen gas in the Local Cloud, we derive a particle density of ionized hydrogen n(H(+)) and electrons n(sub e) of 0.015-0.019/cu cm assuming ionization equilibrium and a helium ionization fraction of less than 20%. These values correspond to a hydrogen ionizatin fraction, chi(sub H) from 19% to 15%, respectively. The range of these derived quantities is due to the uncertainties in the local values of the neutral hydrogen and helium interstellar densities derived from both (1) solar backscatter measurements of Ly alpha lines of hydrogen and helium (1216 and 584 A), and (2) the average neutral densities along the line of sight to nearby stars. The local proton density produced by epsilon CMa is enough to allow the ionization mechanism of Ripken & Fahr (1983) to work at the heliopause and explain the discrepancy between the neutral hydrogen density derived from solar backscatter measurements and line-of-sight averages to nearby stars. A large value of electron density in the Local Cloud of n(sub e) is approximately 0.3-0.7/cu cm (T = 7000 K) has recently been reported by Lallement et al. (1994) using observations of Mg II and Mg I toward Sirius A. We show that if such a high value exists, it cannot result from the EUV stellar radiation field and, therefore, must be due to a strong diffuse source of EUV radiation.

Vallerga, J. V.↗

Monaural Sound Localization Revisited

Research reported during the past few decades has revealed the importance for human sound localization of the so-called 'monaural spectral cues.' These cues are the result of the direction-dependent filtering of incoming sound waves accomplished by the pinnae. One point of view about how these cues are extracted places great emphasis on the spectrum of the received sound at each ear individually. This leads to the suggestion that an effective way of studying the influence of these cues is to measure the ability of listeners to localize sounds when one of their ears is plugged. Numerous studies have appeared using this monaural localization paradigm. Three experiments are described here which are intended to clarify the results of the previous monaural localization studies and provide new data on how monaural spectral cues might be processed. Virtual sound sources are used in the experiments in order to manipulate and control the stimuli independently at the two ears. Two of the experiments deal with the consequences of the incomplete monauralization that may have contaminated previous work. The results suggest that even very low sound levels in the occluded ear provide access to interaural localization cues. The presence of these cues complicates the interpretation of the results of nominally monaural localization studies. The third experiment concerns the role of prior knowledge of the source spectrum, which is required if monaural cues are to be useful. The results of this last experiment demonstrate that extraction of monaural spectral cues can be severely disrupted by trial-to-trial fluctuations in the source spectrum. The general conclusion of the experiments is that, while monaural spectral cues are important, the monaural localization paradigm may not be the most appropriate way to study their role.

Wightman, Frederic L.↗

Scope and Abstraction: Two Criteria for Localized Planning

Localization is a general-purpose representational technique for partitioning problem requirements into subproblems. Localized search utilizes a partitioning by breaking the overall search space into several smaller search spaces, one for each subproblem. Unlike most methods of partitioning, localization allows for subproblems that overlap -- i.e., multiple search spaces may be involved in constructing shared pieces of the overall plan. In this paper we focus on two criteria for forming localizations: abstraction and scope. Abstraction-based localizations are motivated by activation relationships between problem requirements. In contrast, scope-based localizations are motivated by the relevance of problem requirements to specific portions of the overall plan. This paper also describes a method for automatically generating scope and abstraction-based localizations. Empirical results are provided that contrast their use in an office-building construction planning domain.

Lansky, Amy L.↗

Global Aerodynamic Modeling Using Automated Local Model Networks in Real Time

A novel method is presented for automated real-time global aerodynamic modeling using local model networks, known as Smoothed Partitioning with Localized Trees in Real Time (SPLITR), as part of NASA’s Learn-to-Fly technology development initiative. The global nonlinear aerodynamics are partitioned into several local regions known as cells, with the dimension, location, and timing of each partition automatically selected based on a residual characterization procedure, under the constraints of real-time operation. Regression trees represent the successive partitioning of the global flight envelope and describe the evolution of the cell structure. Recursive equation-error least-squares parameter estimation in the time domain is used to estimate a model that represents the local aerodynamics in each region, so that it can be updated independently with non-contiguous data in the range of each cell over time. A weighted superposition of these piecewise local models across the flight envelope forms a global nonlinear model that also accurately captures the local aerodynamics. The SPLITR approach is demonstrated using both simulation and flight data, and the results are analyzed in terms of model predictive capabilities as well as interpretability. The results show that SPLITR can be used to automatically partition complex nonlinear aerodynamic behavior, produce an accurate model, and provide valuable physical insight into the local and global aerodynamics.

Weinstein, Rose↗

Local rollback for fault-tolerance in parallel computing systems

A control logic device performs a local rollback in a parallel super computing system. The super computing system includes at least one cache memory device. The control logic device determines a local rollback interval. The control logic device runs at least one instruction in the local rollback interval. The control logic device evaluates whether an unrecoverable condition occurs while running the at least one instruction during the local rollback interval. The control logic device checks whether an error occurs during the local rollback. The control logic device restarts the local rollback interval if the error occurs and the unrecoverable condition does not occur during the local rollback interval.

97 MATHEMATICS AND COMPUTING↗

Local and global decision fusion for cyber-physical system abnormality detection

Monitoring nodes may generate a series of current monitoring node values over time representing current operation of a cyber-physical system. A decision fusion computer platform may receive, from a local status determination module, an indication of whether each node has an initial local status of “normal”/“abnormal” and a local certainty score (with higher values of the local certainty score representing greater likelihood of abnormality). The computer platform may also receive, from a global status determination module, an indication of whether the system has an initial global status of “normal”/“abnormal” and a global certainty score. The computer platform may output, for each node, a fused local status of “normal” or “abnormal,” at least one fused local status being based on the initial global status. The decision fusion computer platform may also output a fused global status of “normal” or “abnormal” based on at least one initial local status.

Abbaszadeh, Masoud↗

Korean Localization Program for Performance Verification Test of APR1400's RCP

The Korean government together with the Korean nuclear society completed the development of technologies for the design, manufacturing, and performance verification test of the APR1400's Reactor Coolant Pump (RCP) as one of the national programs for the localization of deficient nuclear technology. The RCP localization program was driven by KAERI, which was responsible for the development of the performance verification and evaluation technology, and by DOOSAN heavy industrial company, which was in charge of the design and manufacturing of the RCP. The test facility for the localized APR1400's RCP was constructed at the KAERI site at the end of 2012. The thermal hydraulic and electric capability of the RCP test facility (RCPTF) covers up to 18.5 MPa, 343 deg. C, 11.7 m{sup 3}/s, and 14.0 MW for the design pressure, temperature, flow rate, and maximum electric power, respectively. In 2013, a commissioning test was performed to verify its designed capability, followed by several modifications in the RCPTF including signal processing and control logic to enhance the verification and evaluation capability of the RCP performance. After finishing the commissioning and modification of the RCPTF, a type test for the new-type of RCP was performed successfully. In 2014 and 2015, eight production tests for the localized RCPs, which will be installed in a commercial nuclear power plant in Korea, were successfully completed. As a final stage of the localization program of the RCP, KAERI will perform a seal LOCA test to verify the leakage characteristics and produce experimental data on the localized seal assembly for a safety analysis during a station black out (SBO) condition. In this summary, several technical issues developed through a series of research processes for a performance verification test of the localized RCP are described.

21 SPECIFIC NUCLEAR REACTORS AND ASSOCIATED PLANTS↗