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At least 631 records · Page 35

Rare Earth Extraction and Concentration at Pilot-Scale from North Dakota Coal-Related Feedstocks (Final Technical Report)

The objectives of this project were to design, construct, commission, and operate a pilot-scale system utilizing UND's REE extraction technology from lignite, and complete saleability and economic evaluations of products. The process includes a dilute-acid extraction process from low-rank-coals, followed by selective precipitations and further processing to produce mixed rare earth oxide materials. The pilot was successfully constructed to a 1,000 lb/hr nameplate capacity and tested with over 100 tons of >300-ppm lignite-based feedstocks and produced saleable-quality products during operation. The team successfully attained a TRL status of 6 with the completion and testing of the pilot system, and the technology is poised for demonstration at a commercial scale.

01 COAL, LIGNITE, AND PEAT↗

Development of Design for the STS Extraction Magnet System

The Oak Ridge National Laboratory Second Target Station Project will enhance the Spallation Neutron Source by adding a new neutron source. The upgrade includes a 30% increase in beam energy and a 50% boost in beam current, doubling the accelerator's power capability to 2.8 MW. The Ring-to-Second-Target Beam Transport (RTST) system is vital in directing high-energy proton beams to the target. A key element of the RTST system is the extraction magnets, which are tasked with precise beam extraction and transport. Within the framework of this work, Fermilab is responsible for carrying out the development of 3 types of magnets: Pulsed Dipole, Large Aperture Quadrupole and Narrow Quadrupole.

Chemenok, Vitalii [Unlisted, US]↗

Comparative Analysis of DNA LLM Classification Techniques Using Intra-Layer Feature Extraction with Autoencoder Stacks [Poster]

This project conducts a comparative analysis of DNA LLM classification techniques using Evo2, Grover, and UTRML, focusing on intra-layer feature extraction in Evo2. By extracting features from multiple layers of Evo2 and integrating them into an autoencoder stack with a binary classification head, we evaluate its effectiveness in classifying genomic sequences compared to smaller DNA language models. My findings demonstrate that Evo2 outperforms Grover and UTRML in classification accuracy on a dataset provided by department 08625, CAO2021, while UTRML offers competitive performance with lower computational costs. This study highlights the potential of advanced embedding techniques in enhancing genomic data analysis and informs future research in bioinformatics.

59 BASIC BIOLOGICAL SCIENCES↗

Automated Systems for Solvent Extraction

An automated solvent extraction system for the eventual handling of radioactive materials has been designed and procured for rapid, efficient and safe liquid-liquid extraction processes. This system will be configured to carry out liquid-liquid separations from beginning to end, automating tedious and time-consuming tasks such as organic/aqueous phase prep, pH checks, phase separation, and metal ion analysis. The system features advanced liquid handling capabilities, a robotic arm for precise sample transfer, and sophisticated analytical tools including UV-VIS spectrophotometry for real-time monitoring. Additionally, it incorporates automated capping of vials, vortex mixing, and centrifugation to ensure thorough mixing and phase separation. This report provides an overview of the system and general capabilities as well as initial efforts to develop an automated workflow for liquid-liquid separations.

38 RADIATION CHEMISTRY, RADIOCHEMISTRY, AND NUCLEA↗

Multi-Differential Charged Current 𝝂_𝝁− Argon Cross Section without Pions in the Final State Measurement in MicroBooNE , and Current Status of Simultaneous Cross Section Extraction with ANNIE

MicroBooNE, an 85-tonne liquid argon time projection chamber detector is on-axis to the Booster Neutrino Beam (BNB) at Fermi National Accelerator Laboratory. MicroBooNE is elucidating neutrino interactions with argon through cross-section measurements to refine interaction models and reduce uncertainties. In this poster, we present recent published single and double multi-differential charged current (CC) cross section with zero pions in the final state (CC-0 ) as a function of muon momentum ( ) and the cosine of the muon angle ( ). We present the details of the event selection and the extraction of 1D and 2D cross sections. We further report on the status of a simultaneous cross-section extraction conducted in conjunction with the ANNIE experiment, which employs a Gd-H O target and operates on the same BNB beamline. This joint measurement enables a precision test of nuclear A-dependence between oxygen and argon, with shared flux and cross-section model correlations leading to the cancellation of systematic uncertainties.

Nguyen, Christian Van [Rutgers U., Piscataway] (OR↗

Slow Extraction Beam Commissioning for the Mu2e Experiment at Fermilab

Following the successful completion of the Muon g-2 experiment run at Fermilab, the Muon Campus facility has been reconfigured from delivering 3 GeV muon beams to the g-2 storage ring to providing slow-extracted 8 GeV proton beam spills for the Mu2e experiment. The first full-scale commissioning run with slow extraction was conducted during the 2025 run, followed by the second run in early 2026. We present the results and current status of this commissioning campaign.

Nagaslaev, V. [Fermilab] (ORCID:0000000235719205)↗

Genome Extraction from Shotgun Metagenome Sequence Data

Uncultivated Bacteria and Archaea comprise the vast majority of species on Earth, but obtaining their genomes directly from the environment, using shotgun sequencing, has only recently become possible. To realize the hope of capturing Earth’s microbial genetic complement, technologies that accelerate recovery of high-quality genomes are necessary. We present a series of analysis steps and data products for the extraction of high quality metagenome-assembled genomes (MAGs) from microbiomes using the U.S. Department of Energy Systems Biology Knowledgebase (KBase) platform (http://www.kbase.us/). In KBase, the process is end-to-end, allowing a user to go from the initial sequencing reads all the way through to MAG genomes, which can then be analyzed with other KBase capabilities such as phylogenetic placement, functional assignment, metabolic modeling, pangenome functional profiling, RNA-Seq, and others. While portions of such capabilities are individually available from other resources, the combination of the intuitive usability, data interoperability, and integration of tools in a freely available compute resource makes KBase a uniquely powerful platform for obtaining MAGs from microbiomes. While this workflow offers tools for each of the key steps in the genome extraction process, it also provides a scaffold that can be easily extended, with additional MAG recovery and analysis tools, via the KBase SDK (Software Development Kit).

Chivian, Dylan↗

Optimal vocabulary selection approaches for privacy-preserving deep NLP model training for information extraction and cancer epidemiology

With the use of artificial intelligence and machine learning techniques for biomedical informatics, security and privacy concerns over the data and subject identities have also become an important issue and essential research topic. Without intentional safeguards, machine learning models may find patterns and features to improve task performance that are associated with private personal information. The privacy vulnerability of deep learning models for information extraction from medical textural contents needs to be quantified since the models are exposed to private health information and personally identifiable information. The objective of the study is to quantify the privacy vulnerability of the deep learning models for natural language processing and explore a proper way of securing patients’ information to mitigate confidentiality breaches. The target model is the multitask convolutional neural network for information extraction from cancer pathology reports, where the data for training the model are from multiple state population-based cancer registries. This study proposes the following schemes to collect vocabularies from the cancer pathology reports; (a) words appearing in multiple registries, and (b) words that have higher mutual information. We performed membership inference attacks on the models in high-performance computing environments. The comparison outcomes suggest that the proposed vocabulary selection methods resulted in lower privacy vulnerability while maintaining the same level of clinical task performance.

59 BASIC BIOLOGICAL SCIENCES↗

An Improved Method for Extracting, Sorting, and AMS Dating of Pollen Concentrates From Lake Sediment

High-resolution chronologies are crucial for paleoenvironmental reconstructions, and are particularly challenging for lacustrine records of terrestrial paleoclimate. Accelerator Mass Spectrometry (AMS) radiocarbon measurement of terrestrial macrofossils is the most common technique for building age models for lake sediment cores, but relies on the presence of terrestrial macrofossils in sediments. In the absence of sufficient macrofossils, pollen concentrates represent a valuable source of dates for building high-resolution chronologies. However, pollen isolation and dating may present several challenges, as has been reported by different authors in previous work over the last few decades. Here we present an improved method for extracting, purifying and radiocarbon-dating pollen concentrates using flow cytometry to improve the extraction efficiency and the purity of the pollen concentrates. Overall, the nature of the sediments and the abundance of the pollen represent major considerations in obtaining enough pollen grains and, consequently, enough carbon to be dated. Further, the complete separation of pollen from other forms of organic matter is required to ensure the accuracy of the dates. We apply the method to surface samples and sediment cores recovered from two contrasting lake basins on the eastern side of the Sierra Nevada (California), and describe the variations that may be used to optimize pollen preparation from a variety of sediments.

58 GEOSCIENCES↗

Rice Bran Stabilisation and Oil Extraction Using the Microwave-Assisted Method and Its Effects on GABA and Gamma-Oryzanol Compounds

Rice bran oil (RBO) is a valuable ingredient extracted from rice bran (RB), a side stream of polishing rice grain in the milling process. RBO is rich in bioactive ingredients with potential health benefits, such as gamma-oryzanol (GO) and gamma-aminobutyric acid (GABA). Despite its benefits, the quality of RBO depends on the degree of stabilisation of the RB, which is easily affected by lipase enzymes, and thus needs an effective treatment prior to RBO production. To assess the potential of the microwave-assisted method for RB stabilisation and RBO extraction, three Carolino rice varieties (Ariete, Teti, Luna) were tested. The effect of RB stabilisation was evaluated via acid value, water absorption, and GO and GABA levels. The RBO yield was optimised by solvent, temperature, and solvent-to-sample ratio, and the GO and fatty acid levels were determined. The RB stabilisation for the Luna variety did not affect the GO and GABA; for the Ariete and Teti varieties, the GO decreased by 34.4% and 24.2%, and the GABA increased by 26.5% and 47.0%, respectively. The GO levels in RBO samples were not affected by RB stabilisation. The RBO nutritional value was confirmed by the suitable ratio (>2) between polyunsaturated (PUFA) and saturated fatty acids (SFA), with the Teti variety presenting the highest ratio.

Reis, Núria (ORCID:0000000194339109)↗

Eucalyptus Wood Smoke Extract Elicits a Dose-Dependent Effect in Brain Endothelial Cells

The frequency, duration, and size of wildfires have been increasing, and the inhalation of wildfire smoke particles poses a significant risk to human health. Epidemiological studies have shown that wildfire smoke exposure is positively associated with cognitive and neurological dysfunctions. However, there is a significant gap in knowledge on how wildfire smoke exposure can affect the blood–brain barrier and cause molecular and cellular changes in the brain. Our study aims to determine the acute effect of smoldering eucalyptus wood smoke extract (WSE) on brain endothelial cells for potential neurotoxicity in vitro. Primary human brain microvascular endothelial cells (HBMEC) and immortalized human brain endothelial cell line (hCMEC/D3) were treated with different doses of WSE for 24 h. WSE treatment resulted in a dose-dependent increase in IL-8 in both HBMEC and hCMEC/D3. RNA-seq analyses showed a dose-dependent upregulation of genes involved in aryl hydrocarbon receptor (AhR) and nuclear factor erythroid 2-related factor 2 (NRF2) pathways and a decrease in tight junction markers in both HBMEC and hCMEC/D3. When comparing untreated controls, RNA-seq analyses showed that HBMEC have a higher expression of tight junction markers compared to hCMEC/D3. In summary, our study found that 24 h WSE treatment increases IL-8 production dose-dependently and decreases tight junction markers in both HBMEC and hCMEC/D3 that may be mediated through the AhR and NRF2 pathways, and HBMEC could be a better in vitro model for studying the effect of wood smoke extract or particles on brain endothelial cells.

60 APPLIED LIFE SCIENCES↗

Modeling Assessment of Tidal Energy Extraction in the Western Passage

Numerical models have been widely used for the resource characterization and assessment of tidal instream energy. The accurate assessment of tidal stream energy resources at a feasibility or project-design scale requires detailed hydrodynamic model simulations or high-quality field measurements. This study applied a three-dimensional finite-volume community ocean model (FVCOM) to simulate the tidal hydrodynamics in the Passamaquoddy–Cobscook Bay archipelago, with a focus on the Western Passage, to assist tidal energy resource assessment. IEC Technical specifications were considered in the model configurations and simulations. The model was calibrated and validated with field measurements. Energy fluxes and power densities along selected cross sections were calculated to evaluate the feasibility of the tidal energy development at several hotspots that feature strong currents. When taking both the high current speed and water depth into account, the model results showed that the Western Passage has great potential for the deployment of tidal energy farms. The maximum extractable power in the Western Passage was estimated using the Garrett and Cummins method. Different criteria and methods recommended by the IEC for resource characterization were evaluated and discussed using a sensitivity analysis of energy extraction for a hypothetical tidal turbine farm in the Western Passage.

16 TIDAL AND WAVE POWER↗

Design of Multi-Stage Solvent Extraction Process for Separation of Rare Earth Elements

Flowsheet design and stage determination for the separation of rare earth elements (REEs) using solvent extraction (SX) is a challenging task because of the chemical similarity of the REEs. Low separation factors between the elements and complex equilibrium chemistry provide unique challenges to designing an efficient flowsheet for the separation of elements. The multi-stage nature of the SX process adds further complexity, making the assessment of products for a proposed design and stage combination difficult. Therefore, to develop a SX flowsheet, it is essential to quantify the performance for various design and separation conditions. This paper attempts to address the challenge by utilizing an equilibrium and process modeling approach. Results from a bench-scale study performed on a 10 g/L rare earth salt mixture were used in studying the extraction/stripping behavior and developing equilibrium models. DEHPA with TBP as a phase modifier was used as an extractant, while hydrochloric acid was utilized as a stripping agent. The results obtained were used in developing extraction/stripping models, which were integrated into a process framework of a SX train in a Matlab/Simulink environment. The models were programmed as a function block routine and used for developing a flowsheet, which was simulated for differing separation and design conditions. To identify optimum stage combinations, a particle swarm optimization (PSO) routine was developed and implemented for each SX train. Recovery and purity of elements of interest were used as objective function criteria. The stage combination leading to the minimization of the objective function was used to identify the optimum stage combination for a series of SX trains to attempt a balance of purity and recovery. The models and optimization method were implemented to separate a feed mixture containing REEs, which indicated that 99.52 and 85.41 percent purity is achievable for Yttrium and Lanthanum separation using 8-12-3 and 10-3-5 stage combination for loading, scrubbing, and striping. The model also indicated difficult separability between neodymium, praseodymium, and cerium.

Srivastava, Vaibhav (ORCID:0000000212645987)↗

A Novel Technique of Extracting UCN Decay Lifetime from Storage Chamber Measurements Dominated by Scattering Losses

The neutron’s lifetime is a critical parameter in the standard model. Its measurements, particularly measurements using both beamline and ultracold neutron storage techniques, have revealed significant tension. In this work, we review the status of the tension between various measurements, especially in light of the insights provided by the β-decay correlation measurements. We revisit the lifetime measurement in a material storage chamber, dominated by losses from scattering off the walls of the storage chamber. The neutron energy spectra and associated uncertainties were, for the first time, well-characterized using storage data alone. Such models have applications in the extraction of the mean time between wall bounces, which is a key parameter for neutron storage disappearance experiments in search of neutron oscillation. A comparison between the loss model and the number of neutrons stored in a single chamber allowed us to extract a neutron lifetime of τn*=880(+158/−78)stat.(+230/−114)sys.s (68.3% C.I.). Though the uncertainty of this lifetime is not competitive with currently available measurements, the highlight of this work is that we precisely identified the systematic sources of uncertainty that contribute to the neutron lifetime measurements in material storage bottles, namely from the uncertainty in the energy spectra, as well as from the storage chamber surface parameters of the Fermi potential and loss per bounce. In doing so, we highlight the underestimation of the uncertainties in the previous Monte Carlo simulations of experiments using the technique of ultracold neutron storage in material bottles.

Mohanmurthy, Prajwal (ORCID:0000000275737010)↗

BNF C-band Scanning ARM Precipitation Radar 2nd Generation (CSAPR-2) Extracted Radar Columns and In-Situ Sensors (RadCLss)

Corrected Moments in Antenna Coordinates (CMAC) calculates quantitative precipitation estimates (QPE) from empirical relationships based on equivalent radar reflectivity factor, specific differ- ential phase, and specific attenuation. To evaluate these empirical relationships, the Extracted Radar Columns and In-Situ Sensors (RADclss) product was developed. Utilizing Py-ART, RAD- clss extracts CMAC radar columns above various ARM and partner locations. These columns are then spatiotemporally synced with in-situ observations at the surface utilizing the Atmospheric data Community Toolkit (ACT; Theisen et al. 2025), allowing direct comparison of radar parameters with rain gauges and laser disdrometers for further investigation.

bankhead↗

Extraction and Analysis of Time Series Data from Building Automation Systems Using Large Language Models

Semantic schemas like Haystack 4, Brick and ASHRAE standard 223 enable the structured, standardized, and machine-readable representation of building data, facilitating interoperability, data integration, and advanced analytics. However, extracting information from these models requires specialized expertise in SPARQL and other programming languages, skills that are not commonly found among building professionals. Recent advancements in Large Language Models (LLMs), such as ChatGPT, enable the construction of queries using natural language, making it easier for individuals to interact with these systems in a manner that resembles everyday speech. However, these methods have not yet been tested on building semantic ontologies. This paper introduces a novel workflow and tool for enabling users to ask questions about a specific building's data, using natural language and receive answers automatically generated by GPT-4o. Our approach integrates semantic ontologies with advanced LLM capabilities to automate three critical steps: (1) generating SPARQL queries to retrieve time series references from ontological models, (2) extracting the corresponding time series data from the Building Automation System, and (3) performing computations and visualizations tailored to the user's query. The proposed method simplifies access to BAS data, allowing both domain experts and non-specialists to conduct sophisticated analyses without needing extensive technical knowledge of semantic web technologies. By demonstrating this pipeline, we facilitate more accessible and scalable data-driven decision-making in building operations and management.

Mulayim, Ozan Baris↗

Lateral stability and control derivatives of a jet fighter airplane extracted from flight test data by utilizing maximum likelihood estimation

A method of parameter extraction for stability and control derivatives of aircraft from flight test data, implementing maximum likelihood estimation, has been developed and successfully applied to actual lateral flight test data from a modern sophisticated jet fighter. This application demonstrates the important role played by the analyst in combining engineering judgment and estimator statistics to yield meaningful results. During the analysis, the problems of uniqueness of the extracted set of parameters and of longitudinal coupling effects were encountered and resolved. The results for all flight runs are presented in tabular form and as time history comparisons between the estimated states and the actual flight test data.

Parrish, R. V.↗