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At least 631 records · Page 35

Lineage frequency time series reveal elevated levels of genetic drift in SARS-CoV-2 transmission in England

Genetic drift in infectious disease transmission results from randomness of transmission and host recovery or death. The strength of genetic drift for SARS-CoV-2 transmission is expected to be high due to high levels of superspreading, and this is expected to substantially impact disease epidemiology and evolution. However, we don’t yet have an understanding of how genetic drift changes over time or across locations. Furthermore, noise that results from data collection can potentially confound estimates of genetic drift. To address this challenge, we develop and validate a method to jointly infer genetic drift and measurement noise from time-series lineage frequency data. Our method is highly scalable to increasingly large genomic datasets, which overcomes a limitation in commonly used phylogenetic methods. We apply this method to over 490,000 SARS-CoV-2 genomic sequences from England collected between March 2020 and December 2021 by the COVID-19 Genomics UK (COG-UK) consortium and separately infer the strength of genetic drift for pre-B.1.177, B.1.177, Alpha, and Delta. We find that even after correcting for measurement noise, the strength of genetic drift is consistently, throughout time, higher than that expected from the observed number of COVID-19 positive individuals in England by 1 to 3 orders of magnitude, which cannot be explained by literature values of superspreading. Our estimates of genetic drift suggest low and time-varying establishment probabilities for new mutations, inform the parametrization of SARS-CoV-2 evolutionary models, and motivate future studies of the potential mechanisms for increased stochasticity in this system.

60 APPLIED LIFE SCIENCES↗

Discovery of 15 A-F Main Sequence Pulsating Star Candidates

Delta Scuti stars, spanning spectral types A to F with masses between 1.5 and 2.5 solar masses, exhibit a complex mix of radial and non-radial pressure modes. This study focuses on 15 Delta Scuti, Gamma Doradus, and Hybrid candidate stars using TESS satellite photometry data with a time series of exposures ranging from 20 to 600 seconds across different sky regions. Employing the prewhitening technique via fast Fourier transforms, significant frequencies are extracted from light curves. Three approximation methods are used to estimate critical stellar parameters such as density, radius, and mass. This research also verifies the variability of these stars, which are currently not classified as variable in databases like SIMBAD.

79 ASTRONOMY AND ASTROPHYSICS↗

Nimbus hydrological observations over the watersheds of the Niger and Indus rivers

As a result of studying the Nimbus imagery over these two watersheds, it is felt that a perspective and understanding of the large scale hydrological processes and their interrelationship has been obtained which could be obtained by no other means in so short a time. In the case of the Niger River a much better appreciation of the flooding process has been obtained along with the role of the Inland Delta in this process. Obviously a knowledge of the spatial and temporal distribution of the snow-melt process in the Indus River watershed is now available that was obtained with minimal effort, as compared to the effort and time that would be required using conventional methods. It seems clear that even the low resolution data easily available from meteorological satellites can be a valuable source of information in the better management of the water resources in these regions.

Salomonson, V. V.↗

Mariner/Jupiter/Saturn navigation in the presence of massive planetary satellites

Orbit determination accuracies attainable during a Mariner/Jupiter/Saturn encounter have been established by means of covariance analyses. Advanced earth-based multistation radiometric data, optical data consisting of star/satellite pictures provided by a narrow-angle TV camera on board the spacecraft, and batch sequential filtering methods were employed. An evaluation of sequential filter sensitivities to errors in modeling small nongravitational spacecraft accelerations is presented. Selected covariances developed in the orbit determination analysis are used in an investigation of the trajectory correction costs associated with a close Ganymede encounter. The 99 percentile Delta V contours in the Ganymede aiming plane are obtained for satellite encounters before or after Jupiter closed approach, and the sources of the dominant contributions to the Delta V costs are identified.

Hildebrand, C. E.↗

Spectral flux from low-density photospheres - Numerical results

Radiative transfer through sharp, quasi-static atmospheres whose opacity is dominated by hydrogen is considered at densities low enough that scattering usually dominates absorption and radiative excitations usually dominate collisional excitations. Numerical results for the continuum spectral flux are obtained for effective temperatures T(e) = 6000-16,000 K and scale heights Delta-R = 10 to the 10th - 10 to the 14th cm. Spectra are significantly different than if LTE level populations were assumed. Comparison with observations of the Type II supernova 1980k tends to increase the value of the Hubble constant previously obtained by the Baade (1926) method.

Hershkowitz, S.↗

Comparative accuracy of selected multiple scattering approximations

Doubling method computational results which have yielded plane albedo, total transmission and fractional absorption for plane-parallel atmospheres composed of cloud droplets are presently compared with data obtained with selected radiative transfer approximations. The relative and absolute accuracies of asymptotic theory for thick layers and delta-Eddington, Meador-Weaver (1980) and Coakley-Chylek (1975) approximations are compared as a function of optical thickness, solar zenith angle, and single scattering albedo. The delta-Eddington approximation is the most accurate for conservative scattering when the solar zenith angle is small, while Meador-Weaver is the most accurate for nonconservative scattering.

King, M. D.↗

Land Surface Temperature Measurements from EOD MODIS Data

We made more tests of the version 2.0 daily Level 2 and Level 3 Land-Surface Temperature (LST) code (PGE 16) jointly with the MODIS Science Data Support Team (SDST). After making minor changes a few times, the PGE16 code has been successfully integrated and tested by MODIS SDST, and recently has passed the inspection at the Goddard Distributed Active Archive Center (DAAC). We conducted a field campaign in the area of Mono Lake, California on March 10, 1998, in order to validate the MODIS LST algorithm in cold and dry conditions. Two MODIS Airborne Simulator (MAS) flights were completed during the field campaign, one before noon, and another around 10 pm PST. The weather condition for the daytime flight was perfect: clear sky, the column water vapor measured by radiosonde around 0.3 cm, and wind speed less than a half meter per second. The quality of MAS data is good for both day and night flights. We analyzed the noise equivalent temperature difference (NE(delta)T) and the calibration accuracy of the seven MAS thermal infrared (TIR) bands, that are used in the MODIS day/night LST algorithm, with daytime MAS data over four flat homogeneous study areas: two on Grant Lake (covered with ice and snow, respectively), one on Mono Lake, and another on the snow field site where we made field measurements. NE(delta)T ranges from 0.2 to 0.6 k for bands 42, 45, 46, and 48. It ranges from 0.8 to 1.1 K for bands 30-32. The day and night MAS data have been used to retrieve surface temperature and emissivities in these bands. A simple method to correct the effect of night thin cirrus has been incorporated into the day/night LST algorithm in dry atmospheric conditions. We compared the retrieved surface temperatures with those measured with TIR spectrometer, radiometers and thermistors in the snow test site, and the retrieved emissivity images with topographic map. The daytime LST values match well within 1 K. The night LST retrieved from MAS data is 3.3 K colder than those from field measurements most likely because of the effect of haze at night. The good agreement among the regional averaged surface temperatures obtained from LST values retrieved at different resolutions increased our confidence in the MODIS day/night LST algorithm.

Wan, Zheng-Ming↗

Enhanced Stationkeeping Maneuver Control Technique for Delta-V Cost Reduction in the Korea Pathfinder Lunar Orbiter

Final document is attached. This paper proposes an enhanced control technique for stationkeeping maneuvers to reduce delta-v costs for the Korea Pathfinder Lunar Orbiter (KPLO). A scheduled circularization control technique exploits patterns in the evolution of the line of apsides and eccentricity to achieve a significant reduction in stationkeeping delta-v costs based on spacecraft requirements. The technique is compared against previous algorithms implemented for maneuver operations of the Lunar Prospector and Lunar Reconnaissance Orbiter (LRO) missions in the USA and KAGUYA in Japan. Through Monte Carlo analysis, the efficacy and robustness of the proposed method are verified, and the technique is shown to meet the operational requirements of KPLO.

Davis, Diane C.↗

Adaptive Deployable Entry Placement Technology (ADEPT) Development for Small Sat Class Venus Missions

The Adaptable, Deployable Entry and Placement Technology (ADEPT) is a novel approach for entry vehicle design. Similar to an umbrella, it is stowed during launch and deployed prior to entry. ADEPT employs a high performance, 3-D woven, carbon fabric to serve as the primary surface of the mechanically deployed system. The successful ADEPT sounding rocket flight test matured the 1-meter Class ADEPT in the areas of deployment and structural integrity, and provided aerodynamic flight characteristics of the ADEPT open-back configuration from Mach 3 to Mach 0.3. Aerocapture uses the aerodynamic drag from a single hyperbolic atmospheric pass to provide the delta-V needed for orbit insertion. Studies suggest that, compared to propulsive orbit insertion, aerocapture could increase delivered payload by 70 percent at Venus. Drag modulation aerocapture, which shows promise of being simpler and more cost-effective than the more-often studied lift modulation methods, uses in-flight transformations of an entry vehicle's drag area to control the amount of deceleration produced during an atmospheric pass. In single-event drag modulation, a drag device is jettisoned after the appropriate deceleration. ADEPT, due to its unique ability to fold and unfold, is being considered for this SmallSat class payload mission applications.

Cassell, Alan M.↗

Computation of space shuttle flow fields using noncentered finite-difference schemes.

Second- and third-order, noncentered finite-difference schemes are described for the numerical solution of the hyperbolic equations of fluid dynamics. The advantages of noncentered methods over the more conventional centered schemes are: simpler programming logic, nonhomogeneous terms are easily included, and generalization to multidimensional problems is direct. Second- and third-order methods are compared with regard to dissipative and dispersive errors and shock-capturing ability. These schemes are then used in a shock-capturing technique to determine the inviscid, supersonic flow field surrounding space shuttle vehicles (SSV). Resulting flow fields about typical pointed and blunted, delta-winged SSVs at angle of attack are presented and compared with experiment.

Kutler, P.↗

A digital audio/video interleaving system

A method of interleaving an audio signal with its associated video signal for simultaneous transmission or recording, and the subsequent separation of the two signals, is described. Comparisons are made between the new audio signal interleaving system and the Skylab Pam audio/video interleaving system, pointing out improvements gained by using the digital audio/video interleaving system. It was found that the digital technique is the simplest, most effective and most reliable method for interleaving audio and/or other types of data into the video signal for the Shuttle Orbiter application. Details of the design of a multiplexer capable of accommodating two basic data channels, each consisting of a single 31.5-kb/s digital bit stream are given. An adaptive slope delta modulation system is introduced to digitize audio signals, producing a high immunity of work intelligibility to channel errors, primarily due to the robust nature of the delta-modulation algorithm.

Richards, R. W.↗

A strawman targeting technique for spinner spacecraft in the presence of pointing uncertainty

A graphical method that allows the selection of the attitude orientation of a spinner spacecraft prior to the application of a single fixed magnitude velocity change to effect a desired orbit transfer is presented. The selection of the final pointing vector along or opposite to which the desired Delta-V is applied, takes into account pointing errors due to initial attitude determination uncertainty and execution errors introduced during the rhumb line precession of the spin axis. The characterization of the target space in terms of any achieved orbit parameters of interest as well as the final pointing uncertainty is sufficient to determine the right final attitude that insures satisfaction of mission requirements.

Kechichian, J. A.↗

A user's manual for the Electromagnetic Surface Patch code: ESP version 3

This report serves as a user's manual for Version III of the Electromagnetic Surface Patch Code or ESP code. ESP is user-oriented, based on the method of moments (MM) for treating geometries consisting of an interconnection of thin wires and perfectly conducting polygonal plates. Wire/plate junctions must be about 0.1 lambda or more from any plate edge. Several plates may intersect along a common edge. Excitation may be by either a delta-gap voltage generator or by a plane wave. The thin wires may have finite conductivity and also may contain lumped loads. The code computes most of the usual quantities of interest such as current distribution, input impedance, radiation efficiency, mutual coupling, far zone gain patterns (both polarizations) and radar-cross-section (both/cross polarizations).

Newman, E. H.↗

An overview of selected NASP aeroelastic studies at the NASA Langley Research Center

Following an initial discussion of the NASP flight environment, the results of recent aeroelastic testing of NASP-type highly swept delta-wing models in Langley's Transonic Dynamics Tunnel (TDT) are summarized. Subsonic and transonic flutter characteristics of a variety of these models are described, and several analytical codes used to predict flutter of these models are evaluated. These codes generally provide good, but conservative predictions of subsonic and transonic flutter. Also, test results are presented on a nonlinear transonic phenomena known as aileron buzz which occurred in the wind tunnel on highly swept delta wings with full-span ailerons. An analytical procedure which assesses the effects of hypersonic heating on aeroelastic instabilities (aerothermoelasticity) is also described. This procedure accurately predicted flutter of a heated aluminum wing on which experimental data exists. Results are presented on the application of this method to calculate the flutter characteristics of a fine-element model of a generic NASP configuration. Finally, it is demonstrated analytically that active controls can be employed to improve the aeroelastic stability and ride quality of a generic NASP vehicle flying at hypersonic speeds.

Spain, Charles V.↗

Divergence Free High Order Filter Methods for Multiscale Non-ideal MHD Flows

Low-dissipative high order filter finite difference methods for long time wave propagation of shock/turbulence/combustion compressible viscous MHD flows has been constructed. Several variants of the filter approach that cater to different flow types are proposed. These filters provide a natural and efficient way for the minimization of the divergence of the magnetic field (Delta . B) numerical error in the sense that no standard divergence cleaning is required. For certain 2-D MHD test problems, divergence free preservation of the magnetic fields of these filter schemes has been achieved.

Yee, H. C.↗

Kepler Observations of Rapid Optical Variability in the BL Lac Object W2r192+42

We present the first Kepler monitoring of a strongly variable BL Lac, W2R1926+42. The light curve covers 181 days with approx. 0.2% errors, 30 minute sampling and >90% duty cycle, showing numerous delta-I/I > 25% flares over timescales as short as a day. The flux distribution is highly skewed and non-Gaussian. The variability shows a strong rms-flux correlation with the clearest evidence to date for non-linearity in this relation. We introduce a method to measure periodograms from the discrete autocorrelation function, an approach that may be well-suited to a wide range of Kepler data. The periodogram is not consistent with a simple power-law, but shows a flattening at frequencies below 7x10(exp -5) Hz. Simple models of the power spectrum, such as a broken power law, do not produce acceptable fits, indicating that the Kepler blazar light curve requires more sophisticated mathematical and physical descriptions than currently in use.

galaxies↗

Arcminute fluctuations in the microwave background from clusters of galaxies

A method for computing arcmin microwave fluctuations produced by Compton scattering of the cosmic background photons by hot electrons in clusters of galaxies is described. Microwave images of the sky for a range of Omega and primordial fluctuation spectral index n are generated which are then 'observed' to determine Delta T/T in precisely the same manner as actual observations to determine if the cluster-induced fluctuations are consistent with the measured upper limit. The geometry used by Uson and Wilkinson (1984) in the NRAO experiment and Readhead et al. (1989) in the OVRO experiment are applied to the simulated images. The 95 percent confidence lower limit for Omega is found to be about 1/10 for n = -1 (which approximates the CDM mass spectrum for clusters), while for n = 0 it is 1/7; for n = +1 the limit is 1/5 if the gas density profile extends to five core radii.

Markevitch, M.↗

A Parallel Incompressible Navier-Stokes Solver with Multigrid Iterations

We developed a parallel, numerically accurate and stable, and computationally efficient finate-difference incompressible Navier-Stokes (N-S) fluid flow solver. The solver runs on both sequential and massively parallel computers. The numerical method used here is a second-order projection method on a staggered grid. The code is highly modular and it can be used either as a stand-alone flow solver and or a template code which can be adapted or expanded to a specific application. Numerical results and parallel performances of our code on Intel Delta and Paragon are reported.

Navier-Stokes solver↗