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At least 613 records · Page 34

Characterization of Uranium Ore Concentrate Chemical Composition via Raman Spectroscopy

Uranium Ore Concentrate (UOC, often called yellowcake) is a generic term that describes the initial product resulting from the mining and subsequent milling of uranium ores en route to production of the U-compounds used in the fuel cycle. Depending on the mine, the ore, the chemical process, and the treatment parameters, UOC composition can vary greatly. With the recent advent of handheld spectrometers, we have chosen to investigate whether either commercial off-the-shelf (COTS) handheld devices or laboratory-grade Raman instruments might be able to i) identify UOC materials, and ii) differentiate UOC samples based on chemical composition and thus suggest the mining or milling process. Twenty-eight UOC samples were analyzed via FT-Raman spectroscopy using both 1064 nm and 785 nm excitation wavelengths. These data were also compared with results from a newly developed handheld COTS Raman spectrometer using a technique that lowers background fluorescence signal. Initial chemometric analysis was able to differentiate UOC samples based on mine location. Additional compositional information was obtained from the samples by performing XRD analysis on a subset of samples. The compositional information was integrated with chemometric analysis of the spectroscopic dataset allowing confirmation that class identification is possible based on compositional differences between the UOC samples, typically involving species such as U3O8, α-UO2(OH)2, UO4•2H2O (metastudtite), K(UO2)2O3, etc. While there are clearly excitation λ sensitivities, especially for dark samples, Raman analysis coupled with chemometric data treatment can nicely differentiate UOC samples based on composition and even mine origin.

Su, Yin-Fong↗

Exploration of the Moon with Remote Sensing, Ground-Penetrating Radar, and the Regolith-Evolved Gas Analyzer (REGA)

There are two important reasons to explore the Moon. First, we would like to know more about the Moon itself: its history, its geology, its chemistry, and its diversity. Second, we would like to apply this knowledge to a useful purpose. namely finding and using lunar resources. As a result of the recent Clementine and Lunar Prospector missions, we now have global data on the regional surface mineralogy of the Moon, and we have good reason to believe that water exists in the lunar polar regions. However, there is still very little information about the subsurface. If we wish to go to the lunar polar regions to extract water, or if we wish to go anywhere else on the Moon and extract (or learn) anything at all, we need information in three dimensions an understanding of what lies below the surface, both shallow and deep. The terrestrial mining industry provides an example of the logical steps that lead to an understanding of where resources are located and their economic significance. Surface maps are examined to determine likely locations for detailed study. Geochemical soil sample surveys, using broad or narrow grid patterns, are then used to gather additional data. Next, a detailed surface map is developed for a selected area, along with an interpretation of the subsurface structure that would give rise to the observed features. After that, further sampling and geophysical exploration are used to validate and refine the original interpretation, as well as to make further exploration/ mining decisions. Integrating remotely sensed, geophysical, and sample datasets gives the maximum likelihood of a correct interpretation of the subsurface geology and surface morphology. Apollo-era geophysical and automated sampling experiments sought to look beyond the upper few microns of the lunar surface. These experiments, including ground-penetrating radar and spectrometry, proved the usefulness of these methods for determining the best sites for lunar bases and lunar mining operations.

Cooper, B. L.↗

A CCD integrated circuit for transient recorders

A 50 MHz CCD integrated circuit is described that was developed for use in transient analog signal recorders to sample and time expand transient signals. The integrated circuit achieves an effective 200 MHz sample rate by using four 32 stage peristaltic CCDs to sample the transient signal four times each clock period. Dual frequency, 4 phi clocking is used to sample and time expand the sampled data. The output signals of the four CCDs are multiplexed on chip into a single low frequency output data line. When operated with 50 MHz/165 KHz 4 phi clocks, this circuit has a 200 MHz sample rate, a record length of 640 nanoseconds, a time expansion factor of 303, and overall signal to noise ratio of 40:1. The signal to noise ratio is limited by fixed pattern noise of the four CCDs.

Balch, J. W.↗

A Synthetic Vision Preliminary Integrated Safety Analysis

This report documents efforts to analyze a sample of aviation safety programs, using the LMI-developed integrated safety analysis tool to determine the change in system risk resulting from Aviation Safety Program (AvSP) technology implementation. Specifically, we have worked to modify existing system safety tools to address the safety impact of synthetic vision (SV) technology. Safety metrics include reliability, availability, and resultant hazard. This analysis of SV technology is intended to be part of a larger effort to develop a model that is capable of "providing further support to the product design and development team as additional information becomes available". The reliability analysis portion of the effort is complete and is fully documented in this report. The simulation analysis is still underway; it will be documented in a subsequent report. The specific goal of this effort is to apply the integrated safety analysis to SV technology. This report also contains a brief discussion of data necessary to expand the human performance capability of the model, as well as a discussion of human behavior and its implications for system risk assessment in this modeling environment.

Hemm, Robert↗

Speed and Memory Improvements to MCNP6 Delayed-Gamma Line Treatment

The delayed-gamma (DG) line-emission (line) sampling was first introduced into MCNPX in 2005. At the time, storage demands for problems with large numbers of DG lines was a major concern. In order to accommodate large amounts of line data while keeping the memory footprint of such a problem from exceeding memory limits, complicated logic was included to sift through various storage options. In mid-2015 concerns arose over the adequacy of the MCNP6 DG source option (inherited from MCNPX) with line sampling for modeling high-fidelity problems. One indication that there was a problem came when studying the MCNP6 produced DG spectra of U-238 and its progeny using high-fidelity spectroscopic tallies when compared to DG line amplitudes directly from ENDF/B-VII.1 emission data. Despite producing a correct integral number of gammas, the comparison to ENDF data showed a broadening in the energy lines and a reduction in the amplitude of more prominent lines. It was later found that the cause of this broadening was one of the memory-saving techniques used to store DG line data when problems required many DG lines. Specifically, the DG lines were integrated into fine energy bins for sampling. When a DG line was to be sampled, a random number would be used to choose which energy bin to sample based on emission probability. Once chosen, a second random number was used to perform nearest-line sampling in that bin. The integration of lines led to an oversampling of low-probability lines, especially when in close proximity to high-probability lines. This treatment also caused a similar issue with the time-dependent behavior of DG line emission which occurred when low-probability lines were sampled near high probability lines with the former decay constant being used. The effect on time-dependent gamma production was demonstrated in analytic benchmarks performed by Weldon et al.. To address these issues a new gamma line storage and sampling treatment was introduced in 2015. This new treatment, stores gamma emission data in a line-by-line CDF which is sampled directly, thereby resolving both the line-broadening issue, and the time-dependence issue as was demonstrated by Tutt el al.. In addition, the new DG sampling treatment was written to use dynamically dimensioned storage arrays as opposed to large fixed-dimensioned arrays, as in the former treatment, and also makes more efficient use of line data that is stored by reducing or eliminating repeated data. As a result, storage arrays are generated only for DG data relevant to the problem being executed. The result should be a reduction in both memory requirements and runtime. However, these reductions could not be realized until the logic for the old treatment could be removed. This paper provides an update on recent work which has focused on the removal of the old DG sampling logic and attempts to quantify the memory reduction and speed up of selected problems.

73 NUCLEAR PHYSICS AND RADIATION PHYSICS↗

Automated instant labeling chemistry workflow for real-time monitoring of monoclonal antibody N -glycosylation

With the transition toward continuous bioprocessing, process analytical technology (PAT) is becoming necessary for rapid and reliable in-process monitoring during biotherapeutics manufacturing. Bioprocess 4.0 is looking to build end-to-end bioprocesses that include PAT-enabled real-time process control. This is especially important for drug product quality attributes that can change during bioprocessing, such as protein N-glycosylation, a critical quality attribute for most monoclonal antibody (mAb) therapeutics. Glycosylation of mAbs is known to influence their efficacy as therapeutics and is regulated for a majority of mAb products on the market today. Currently, there is no method to truly measure N-glycosylation using on-line PAT, hence making it impractical to design upstream process control strategies. We recently described the N-GLYcanyzer workflow: an integrated PAT unit that measures mAb N-glycosylation within 3 hours of automated sampling from a bioreactor. Here, we integrated Agilent's Instant Procainamide (InstantPC) based chemistry workflow into the N-GLYcanyzer PAT unit to allow for nearly 10× faster near real-time analysis of mAb glycoforms. Furthermore, our methodology is explained in detail to allow for replication of the PAT workflow as well as present a case study demonstrating the use of this PAT to autonomously monitor a mammalian cell perfusion process at the bench scale to gain increased knowledge of mAb glycosylation dynamics during continuous biologics manufacturing using Chinese hamster ovary (CHO) cells.

37 INORGANIC, ORGANIC, PHYSICAL, AND ANALYTICAL CH↗

Sample Identifiers and Metadata to Support Data Management and Reuse in Multidisciplinary Ecosystem Sciences

Physical samples are foundational entities for research across biological, Earth, and environmental sciences. Data generated from sample-based analyses are not only the basis of individual studies, but can also be integrated with other data to answer new and broader-scale questions. Ecosystem studies increasingly rely on multidisciplinary team-science to study climate and environmental changes. While there are widely adopted conventions within certain domains to describe sample data, these have gaps when applied in a multidisciplinary context. In this study, we reviewed existing practices for identifying, characterizing, and linking related environmental samples. We then tested practicalities of assigning persistent identifiers to samples, with standardized metadata, in a pilot field test involving eight United States Department of Energy projects. Participants collected a variety of sample types, with analyses conducted across multiple facilities. We address terminology gaps for multidisciplinary research and make recommendations for assigning identifiers and metadata that supports sample tracking, integration, and reuse. Furthermore, our goal is to provide a practical approach to sample management, geared towards ecosystem scientists who contribute and reuse sample data.

54 ENVIRONMENTAL SCIENCES↗

Quantitative infrared spectroscopy of environmentally sensitive and rough materials

Fourier transform infrared (FTIR) spectroscopy is a widely used characterization technique for studying chemical compositions and lightmatter interactions in the infrared range. However, it remains challenging to use conventional FTIR equipment to characterize materials that are environmentally sensitive and/or have rough surfaces due to their dynamic response to external stimuli (e.g., humidity) and light scattering from the sample surface. Here, we describe an approach enabling quantitative infrared spectroscopy measurements of these challenging samples, including transmittance, reflectance, and emissivity. We designed and 3D-printed a miniaturized environmental chamber that can be directly inserted into the sample holder of a conventional integrating sphere to perform total transmission and reflection measurements in controlled environments. Moreover, a calibration method was developed to exclude light scattering from rough surfaces of the sample and the distortion created by infrared windows. To illustrate the potential application of this method, we have performed quantitative infrared measurements, both specular and diffusive, on a sapphire standard reference with a specular surface, as well as a textile sample that has a rough surface and is dynamically responsive to changes in humidity. The calibrated results measured with the equipped chamber match those measured without the IR windows, demonstrating the viability of our environmental chamber and the proposed calibration method. This quantitative infrared spectroscopy measurement technique may help advance fields such as metasurfaces and adaptive textiles, where samples are often rough, dynamically responsive, and/or environmentally sensitive.

3D printing↗

Investigation, development and application of optimal output feedback theory. Volume 2: Development of an optimal, limited state feedback outer-loop digital flight control system for 3-D terminal area operation

This report contains the development of a digital outer-loop three dimensional radio navigation (3-D RNAV) flight control system for a small commercial jet transport. The outer-loop control system is designed using optimal stochastic limited state feedback techniques. Options investigated using the optimal limited state feedback approach include integrated versus hierarchical control loop designs, 20 samples per second versus 5 samples per second outer-loop operation and alternative Type 1 integration command errors. Command generator tracking techniques used in the digital control design enable the jet transport to automatically track arbitrary curved flight paths generated by waypoints. The performance of the design is demonstrated using detailed nonlinear aircraft simulations in the terminal area, frequency domain multi-input sigma plots, frequency domain single-input Bode plots and closed-loop poles. The response of the system to a severe wind shear during a landing approach is also presented.

Broussard, J. R.↗

HYBRID MANUFACTURING TECHNIQUE USING LARGE-SCALE ADDITIVE MANUFACTURING AND COMPRESSION MOLDING FOR HIGH PERFORMANCE COMPOSITES

Additive Manufacturing (AM) or 3-D printing has moved from small-scale prototypes to large-scale functional structures. With the introduction of large-scale 3D printers into the market a new industry has been born. For the first time, we are presenting the idea of preparing large-scale 3-D printed β-stage preforms to be used in traditional compression molding (CM) manufacturing technique to prepare final functional structures. Short carbon fiber (CF) reinforced material acrylonitrile butadiene Styrene i.e. ABS with 20% CF is used in present work. It is shown that highly aligned 3D printed short carbon fiber composite maintains its orientation after compression molding. A sandwich panel is prepared to show the capability to prepare complicated parts by integrating AM and CM. Interphase of the prepared dissimilar material is also studied using SEM. Samples prepared using AM-CM integration showed 11% and 79 % improvement in tensile strength and tensile modulus respectively compared to the traditional extrusion compression molding (ECM) process.

Kumar, Vipin↗

FIDO - Video File

Field Integrated Design and Operations (FIDO) rover is a prototype of the Mars Sample Return rovers that will carry the integrated Athena Science Payload to Mars in 2003 and 2005. The purpose of FIDO is to simulate, using Mars analog settings, the complex surface operations that will be necessary to find, characterize, obtain, cache, and return samples to the ascent vehicles on the landers. This videotape shows tests of the FIDO in the Mojave Desert. These tests include drilling through rock and movement of the rover. Also included in this tape are interviews with Dr Raymond Arvidson, the test director for FIDO, and Dr. Eric Baumgartner, Robotics Engineer at the Jet Propulsion Laboratory.

Source record↗

Microgravity science experiment integration - When the PI and the PED differ

This paper addresses issues related to the integration of principal investigators (PIs) and payload-element developers (PEDs) for conducting effective microgravity experiments. The Crystal Growth Furnace (CGF) is used as an example to demonstrate the key issues related to the integration of a PI's sample into a facility run by a different organization. Attention is given to the typical preflight timeline, documentation required for experimental implementation, and hardware deliverables. A flow chart delineates the payload-integration process flow, and PI inputs required for an experiment include equipment and procedure definitions, detailed design and fabrication of the experiment-specific equipment, and specifications of the contract-end item. The present analysis is of interest to the coordination of effective microgravity experiments on the Space Station Freedom that incorporate PIs and PEDs from different organizations.

Baer-Peckham, M. S.↗

Principles, Techniques, and Applications of Tissue Microfluidics

The principle of tissue microfluidics and its resultant techniques has been applied to cell analysis. Building microfluidics to suit a particular tissue sample would allow the rapid, reliable, inexpensive, highly parallelized, selective extraction of chosen regions of tissue for purposes of further biochemical analysis. Furthermore, the applicability of the techniques ranges beyond the described pathology application. For example, they would also allow the posing and successful answering of new sets of questions in many areas of fundamental research. The proposed integration of microfluidic techniques and tissue slice samples is called tissue microfluidics because it molds the microfluidic architectures in accordance with each particular structure of each specific tissue sample. Thus, microfluidics can be built around the tissues, following the tissue structure, or alternatively, the microfluidics can be adapted to the specific geometry of particular tissues. By contrast, the traditional approach is that microfluidic devices are structured in accordance with engineering considerations, while the biological components in applied devices are forced to comply with these engineering presets. The proposed principles represent a paradigm shift in microfluidic technology in three important ways: Microfluidic devices are to be directly integrated with, onto, or around tissue samples, in contrast to the conventional method of off-chip sample extraction followed by sample insertion in microfluidic devices. Architectural and operational principles of microfluidic devices are to be subordinated to suit specific tissue structure and needs, in contrast to the conventional method of building devices according to fluidic function alone and without regard to tissue structure. Sample acquisition from tissue is to be performed on-chip and is to be integrated with the diagnostic measurement within the same device, in contrast to the conventional method of off-chip sample prep and subsequent insertion into a diagnostic device. A more advanced form of tissue integration with microfluidics is tissue encapsulation, wherein the sample is completely encapsulated within a microfluidic device, to allow for full surface access. The immediate applications of these approaches lie with diagnostics of tissue slices and biopsy samples e.g. for cancer but the approaches would also be very useful in comparative genomics and other areas of fundamental research involving heterogeneous tissue samples.

Wade, Lawrence A.↗

BEYONDPLANCK XIII. Intensity foreground sampling, degeneracies, and priors

We present the intensity foreground algorithms and model employed within the BEYONDPLANCK analysis framework. The BEYONDPLANCK analysis is aimed at integrating component separation and instrumental parameter sampling within a global framework, leading to complete end-to-end error propagation in the Planck Low Frequency Instrument (LFI) data analysis. Given the scope of the BEYONDPLANCK analysis, a limited set of data is included in the component separation process, leading to foreground parameter degeneracies. In order to properly constrain the Galactic foreground parameters, we improve upon the previous Commander component separation implementation by adding a suite of algorithmic techniques. These algorithms are designed to improve the stability and computational efficiency for weakly constrained posterior distributions. These are: (1) joint foreground spectral parameter and amplitude sampling, building on ideas from MIRAMARE; (2) component-based monopole determination; (3) joint spectral parameter and monopole sampling; and (4) application of informative spatial priors for component amplitude maps. We find that the only spectral parameter with a significant signal-to-noise ratio using the current BEYONDPLANCK data set is the peak frequency of the anomalous microwave emission component, for which we find $ν$ p = 25.3 ± 0.5 GHz; all others must be constrained through external priors. Future works will be aimed at integrating many more data sets into this analysis, both map and time-ordered based, thereby gradually eliminating the currently observed degeneracies in a controlled manner with respect to both instrumental systematic effects and astrophysical degeneracies. When this happens, the simple LFI-oriented data model employed in the current work will need to be generalized to account for both a richer astrophysical model and additional instrumental effects. This work will be organized within the Open Science-based COSMOGLOBE community effort.

79 ASTRONOMY AND ASTROPHYSICS↗

Measurement of the azimuthal anisotropy of charged particles produced in $\sqrt{s_{_\text {NN}}}$ = 5.02 TeV Pb+Pb collisions with the ATLAS detector

Measurements of the azimuthal anisotropy in lead–lead collisions at $\sqrt{s_{_\text {NN}}}$ = 5.02 TeV are presented using a data sample corresponding to 0.49 nb -1 integrated luminosity collected by the ATLAS experiment at the LHC in 2015. The recorded minimum-bias sample is enhanced by triggers for “ultra-central” collisions, providing an opportunity to perform detailed study of flow harmonics in the regime where the initial state is dominated by fluctuations. The anisotropy of the charged-particle azimuthal angle distributions is characterized by the Fourier coefficients, v 2 - v 7 , which are measured using the two-particle correlation, scalar-product and event-plane methods. The goal of the paper is to provide measurements of the differential as well as integrated flow harmonics v n over wide ranges of the transverse momentum, 0.5 < p T < 60 GeV, the pseudorapidity, |η|< 2.5, and the collision centrality 0–80%. Results from different methods are compared and discussed in the context of previous and recent measurements in Pb+Pb collisions at $\sqrt{s_{_\text {NN}}}$ = 2.76 TeV and 5.02 TeV . In particular, the shape of the p T dependence of elliptic or triangular flow harmonics is observed to be very similar at different centralities after scaling the v n and p T values by constant factors over the centrality interval 0–60% and the p T range 0.5 < p T < 5 GeV.

72 PHYSICS OF ELEMENTARY PARTICLES AND FIELDS↗

Mobile/Modular BSL-4 Facilities for Meeting Restricted Earth Return Containment Requirements

NASA robotic sample return missions designated Category V Restricted Earth Return by the NASA Planetary Protection Office require sample containment and biohazard testing in a receiving laboratory as directed by NASA Procedural Requirement (NPR) 8020.12D - ensuring the preservation and protection of Earth and the sample. Currently, NPR 8020.12D classifies Restricted Earth Return for robotic sample return missions from Mars, Europa, and Enceladus with the caveat that future proposed mission locations could be added or restrictions lifted on a case by case basis as scientific knowledge and understanding of biohazards progresses. Since the 1960s, sample containment from an unknown extraterrestrial biohazard have been related to the highest containment standards and protocols known to modern science. Today, Biosafety Level (BSL) 4 standards and protocols are used to study the most dangerous high-risk diseases and unknown biological agents on Earth. Over 30 BSL-4 facilities have been constructed worldwide with 12 residing in the United States; of theses, 8 are operational. In the last two decades, these brick and mortar facilities have cost in the hundreds of millions of dollars dependent on the facility requirements and size. Previous mission concept studies for constructing a NASA sample receiving facility with an integrated BSL-4 quarantine and biohazard testing facility have also been estimated in the hundreds of millions of dollars. As an alternative option, we have recently conducted an initial trade study for constructing a mobile and/or modular sample containment laboratory that would meet all BSL-4 and planetary protection standards and protocols at a faction of the cost. Mobile and modular BSL-2 and 3 facilities have been successfully constructed and deployed world-wide for government testing of pathogens and pharmaceutical production. Our study showed that a modular BSL-4 construction could result in approximately 90% cost reduction when compared to traditional construction methods without compromising the preservation of the sample or Earth.

Calaway, M. J.↗

Photometric Signature of Ultraharmonic Resonances in Barred Galaxies

Bars may induce morphological features, such as rings, through their resonances. Previous studies suggested that the presence of "dark gaps," or regions of a galaxy where the difference between the surface brightness along the bar major axis and that along the bar minor axis is maximal, can be attributed to the location of bar corotation. Here, using GALAKOS, a high-resolution N-body simulation of a barred galaxy, we test this photometric method's ability to identify the bar corotation resonance. Contrary to previous work, our results indicate that "dark gaps" are a clear sign of the location of the 4:1 ultraharmonic resonance instead of bar corotation. Measurements of the bar corotation can indirectly be inferred using kinematic information, e.g., by measuring the shape of the rotation curve. We demonstrate our concept on a sample of 578 face-on barred galaxies with both imaging and integral field observations and find that the sample likely consists primarily of fast bars.

79 ASTRONOMY AND ASTROPHYSICS↗

Mars Science Laboratory Drill

This drill (see Figure 1) is the primary sample acquisition element of the Mars Science Laboratory (MSL) that collects powdered samples from various types of rock (from clays to massive basalts) at depths up to 50 mm below the surface. A rotary-percussive sample acquisition device was developed with an emphasis on toughness and robustness to handle the harsh environment on Mars. It is the first rover-based sample acquisition device to be flight-qualified (see Figure 2). This drill features an autonomous tool change-out on a mobile robot, and novel voice-coil-based percussion. The drill comprises seven subelements. Starting at the end of the drill, there is a bit assembly that cuts the rock and collects the sample. Supporting the bit is a subassembly comprising a chuck mechanism to engage and release the new and worn bits, respectively, and a spindle mechanism to rotate the bit. Just aft of that is a percussion mechanism, which generates hammer blows to break the rock and create the dynamic environment used to flow the powdered sample. These components are mounted to a translation mechanism, which provides linear motion and senses weight-on-bit with a force sensor. There is a passive-contact sensor/stabilizer mechanism that secures the drill fs position on the rock surface, and flex harness management hardware to provide the power and signals to the translating components. The drill housing serves as the primary structure of the turret, to which the additional tools and instruments are attached. The drill bit assembly (DBA) is a passive device that is rotated and hammered in order to cut rock (i.e. science targets) and collect the cuttings (powder) in a sample chamber until ready for transfer to the CHIMRA (Collection and Handling for Interior Martian Rock Analysis). The DBA consists of a 5/8-in. (.1.6- cm) commercial hammer drill bit whose shank has been turned down and machined with deep flutes designed for aggressive cutting removal. Surrounding the shank of the bit is a thick-walled maraging steel collection tube allowing the powdered sample to be augured up the hole into the sample chamber. For robustness, the wall thickness of the DBA was maximized while still ensuring effective sample collection. There are four recesses in the bit tube that are used to retain the fresh bits in their bit box. The rotating bit is supported by a back-to-back duplex bearing pair within a housing that is connected to the outer DBA housing by two titanium diaphragms. The only bearings on the drill in the sample flow are protected by a spring-energized seal, and an integrated shield that diverts the ingested powdered sample from the moving interface. The DBA diaphragms provide radial constraint of the rotating bit and form the sample chambers. Between the diaphragms there is a sample exit tube from which the sample is transferred to the CHIMRA. To ensure that the entire collected sample is retained, no matter the orientation of the drill with respect to gravity during sampling, the pass-through from the forward to the aft chamber resides opposite to the exit tube.

Okon, Avi B.↗