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At least 613 records · Page 34

Six Month Report on Tissue Cultured Avian Skeletal Myofibers in the STL/A Module Aboard STS-77

Space travel is know to effect skeletal muscle, causing rapid and pronounced atrophy in humans and animals, even when strenuous exercise is used as a countermeasure. The cellular and molecular bases of this atrophy are unknown. Space travel may cause muscle atrophy by a direct effect on the muscle fibers and/or indirectly by reducing circulating levels of growth factors such as growth hormone. The recent development of a tissue culture incubator system for Shuttle Middeck basic science experiments [Space Tissue Loss (STL) Module] by the Walter Reed Army Institute of Research (WRAIR) allows the study of the effects of space travel directly on isolated skeletal myofibers. Avian bioartificial skeletal muscle 'organoids' containing differentiated skeletal myofibers and connective tissue fibroblasts were flown aboard the Space Shuttle (Space Transportation System, STS) on Flight STS-77, a repeat of a similar experiment flown on STS-66. The results from these two flight experiments show for the first time that space travel has a direct effect on skeletal muscle cells separate from any systemic effects resulting from altered circulating growth factors.

Vandenburgh, Herman H.↗

Power Operations of the Mars Exploration Rovers

The rovers of the National Aeronautics and Space Administration’s (NASA) Mars Exploration Rovers (MER) project, Spirit (MER-A) and Opportunity (MER-B), safely landed on the surface of Mars three weeks apart during January 2004. Spirit and Opportunity were built and operated by the Jet Propulsion Laboratory (JPL), which is managed by the California Institute of Technology (Caltech) for NASA. Spirit landed at Gusev Crater, 14.8 degrees south of the equator, and operated continuously on the surface of Mars from January 4, 2004 until last contact from Spirit on March 22, 2010. Opportunity landed at Meridiani Planum, a location 2.5 degrees south of the Martian equator. Opportunity operated continuously on the Martian surface from January 25, 2004 until the last received transmission from Opportunity on June 10, 2018. The goal of the MER project was to determine if Mars ever had a habitable environment, in particular, if it ever had water. During their missions, both Spirit and Opportunity found evidence that liquid water once flowed on the surface of Mars. Both Spirit and Opportunity used a 1.33 m2 triple-junction solar array as their power sources. Based on observations of the original Mars rover, the Sojourner rover of the Mars Pathfinder mission that landed on Mars on July 4, 1997, the expectation was that the Martian dust would rapidly accumulate on the solar arrays of Spirit and Opportunity, and that the rovers would not have enough energy to continue operations after 90 Martian days (sols). Instead, due in part to lower dust accumulation rates than expected and numerous dust cleaning events, the Spirit and Opportunity rovers continued to operate on the Martian surface for over 2000 sols (MER-A) and 5000 sols (MER-B), respectively. During this time, the rovers experienced multiple Martian winters and several dust storms. Because the sources of solar array energy loss were known, the solar array energy output offered a method to scientifically estimate the loading and aeolian removal of dust from the solar arrays each sol. The MER Power operations team called this value that they calculated the solar array Dust Factor (DF). Dust Factor was defined as the fraction of sunlight that penetrates the accumulated dust on the surface of the solar array. A Dust Factor of 1.0 would indicate that the solar array was perfectly clean. A Dust Factor of 0.6 would indicate that only 60% of the available sunlight was able to penetrate the accumulated dust on the solar arrays. The MER Power subsystem operations team used the Multi-Mission Power Analysis Tool (MMPAT) to perform these Dust Factor calculations. The MMPAT software tool modeled the behavior of the solar arrays and the batteries as they interacted with the spacecraft power loads over the mission timeline. MMPAT also had knowledge (through telemetry and user inputs) of telemetered Power subsystem voltages and currents, atmospheric opacity (Tau), rover surface location, rover attitude, the planetary tilt and distance of Mars from the sun based on day of year, the instantaneous elevation of the sun based on time of day, temperatures (internal and external), terrain masking, and shadowing (due to the camera mast and antennas). Once all of the known sources of array energy loss are accounted, the remaining difference between the expected array energy and the actual array energy determines the solar array Dust Factor. The assumptions made while determining the Dust Factor are 1) that the single measured atmospheric opacity value (Tau) is constant over the course of the entire sol, 2) there is no measurable solar cell degradation, 3) there are no shorted strings and therefore, 4) all unexpected solar array energy losses are due to accumulated dust on the solar array. Although it cannot provide an absolute measure of dust loading, the determination of solar array Dust Factor provides a useful way of tracking dust accumulation and aeolian dust removal trends on Martian spacecraft. Any spacecraft on the Martian surface is vulnerable to dust, especially solar-powered spacecraft. The Spirit and Opportunity rovers were operational on the Martian surface for much longer than expected due in part to aeolian removal of dust from their solar arrays. The first few dust removal events were a pleasant surprise to the MER operations teams; however, over time a pattern began to arise. In over three Mars Years on the surface, the Power operations team tracked the solar array Dust Factor at Gusev Crater (location of MER-A) and observed that there were several significant dust removal and deposition events in Mars Year (MY) 27, even in the absence of a large dust storm. In MY 28 at Gusev Crater, the large atmospheric opacity (Tau) increase lagged significant dust removal events. Overall at Gusev Crater, there was a pattern of steady dust accumulation on the solar arrays, with a small number of significant dust cleaning events. At Meridiani Planum, where Opportunity rover operated for over seven Mars Years (late MY 26 to mid MY 34), a clear and consistent pattern of dust movement emerged. Meridiani Planum had a predictable, seasonally dependent pattern of gradual and continuous dust accumulation and removal. In summary, this paper explains the reasons for the development of the solar array Dust Factor and how it was used in mission operations. In particular, this paper describes the MMPAT software package, how it models array energy, including the important assumptions, model inputs and sources of error. And finally, this paper will show how the calculated solar array Dust Factor was used at Gusev Crater and Meridiani Planum to predict dust accumulation rates and weather patterns, and the importance of this generated data set for current and future solar- powered missions to Mars, such as the InSight lander and the planned Mars Sample Return rover.

Chin, Keith B.↗

Erosion of composite materials

A model for describing the response of uncoated and coated fiber reinforced composites subjected to repeated impingements of liquid (rain) droplets is presented. The model is based on the concept that fatigue is the dominant factor in the erosion process. Algebraic expressions are provided which give the incubation period, the rate of mass loss past the incubation period, and the total mass loss of the material during rain impact. The influence of material properties on erosion damage and the protection offered by different coatings are discussed and the use of the model in the design in the design of structures and components is illustrated.

Springer, G. S.↗

Study of controlled diffusion stator blading

Tests were conducted on a high tip speed, highly loaded front compressor stage having low aspect ratio rotor and stator airfoils. The stator airfoils were designed by the controlled diffusion procedure recently developed by P&WA for designing transonic cascade airfoils. The rotor blades consisted of multiple-circular-arc airfoil sections. The stage had a tip speed of 442 m/sec (1450 ft/sec), a hub/tip ratio of 0.597, a rotor aspect ratio of 1.3, and a stator aspect ratio of 1.45. At design speed the rotor-stator stage achieved an adiabatic efficiency of 89.1% at design flow and pressure ratio. Surge margin was 14%. The stage efficiency exceeded the design goal by 0.6 percentage points. The rotor efficiency was 92.4%, exceeding design by 0.3 percentage points. The controlled diffusion stator demonstrated a lower minimum loss over the multiple-circular-arc stator from the root to 70 percent span. A surge diffusion factor of 0.72 was reached at both the rotor tip and the stator root. The NAS3-22008 program demonstrated its intent: high efficiency and loading levels with low aspect ratio blades and the controlled diffusion stator in the unfavorable front stage environment.

Behlke, R. F.↗

High-luminosity carbon stars in the galactic anticenter

K-band magnitudes of 211 carbon stars in the Galactic anticenter are presented. The surface density, brightness range, and observed colors of stars in the sample are discussed. It is suggested that the K-band extinction gradient in the Galactic plane near l = 180 deg is between 0.15 and 0.3/kpc. In contrast to the total density of stars, it is found that the density of high-luminosity carbon stars does not decrease in the anticenter region out to at least 3 kpc from the sun. It is proposed that this is due to the fact that lower metallicity stars spend more time as carbon stars compared to stars of solar metallicity. Also, it is shown that the average mass-loss rates from high-luminosity carbon stars in the anticenter direction appear to be lower by a factor of 1.7 than those for carbon stars in the solar neighborhood.

Jura, M.↗

Mass loss in main-sequence A-type stars?

We present new observations of the H-alpha line profile for five main-sequence A-type stars, where very high SNRs were achieved. A search for weak asymmetries was carried out to detect a stellar wind, but the many telluric absorption lines in this range prevent us from taking the full benefit of the high SNRs. This situation was improved by modeling the telluric absorptions to remove them from the observed spectra, but the H-alpha profiles were nevertheless found to be quite symmetric. We calculated the profile of the H-alpha line for a grid of model atmospheres of an A-type star including a weak wind, in order to assess an upper limit on the mass loss rate. The asymmetry is found to be sensitive to the velocity law and to the turbulent velocity of the wind, but its first moment depends much less on them. The upper limits deduced on the mass loss rate are between 1 and 2 x 10 exp -10 solar mass/yr. An improvement up to a factor 10 could be anticipated if new observations could be secured from a much drier location, achieving similar SNRs.

Lanz, T.↗

Detection of Ice Polar Stratospheric Clouds from Assimilation of Atmospheric Infrared Sounder Data

A novel technique is presented for detection of ice polar stratospheric clouds (PSCs) that form at extremely low temperatures in the lower polar stratosphere during winter. Temperature is a major factor in determining abundance of PSCs, which in turn provide surfaces for heterogeneous chemical reactions leading to ozone loss and radiative cooling. The technique infers the presence of ice PSCs using radiances from the Atmospheric Infrared Sounder (AIRS) in the Goddard Earth Observing System version 5 (GEOS-5) data assimilation system. Brightness temperatures are computed from short-term GEOS-5 forecasts for several hundred AIRS channels, using a radiation transfer module. The differences between collocated AIRS observations and these computed values are the observed-minus-forecast (O-F) residuals in the assimilation system. Because the radiation model assumes clear-sky conditions, we hypothesize that these O-F residuals contain quantitative information about PSCs. This is confirmed using sparse data from the Polar Ozone and Aerosol Measurement (POAM) III occultation instrument. The analysis focuses on 0-F residuals for the 6.79pm AIRS moisture channel. At coincident locations, when POAM III detects ice clouds, the AIRS O-F residuals for this channel are lower than -2K. When no ice PSCs are evident in POAM III data, the AIRS 0-F residuals are larger. Given this relationship, the high spatial density of AIRS data is used to construct maps of regions where 0-F residuals are lower than -2K, as a proxy for ice PSCs. The spatial scales and spatio-temporal variations of these PSCs in the Antarctic and Arctic are discussed on the basis of these maps.

Stajner, Ivanka↗

Decline of Monarch Butterflies Overwintering in Mexico- Is the Migratory Phenomenon at Risk?

1.During the 2009-2010 overwintering season and following a 15-year downward trend, the total area in Mexico occupied by the eastern North American population of overwintering monarch butterflies reached an all-time low. Despite an increase, it remained low in 2010-2011. 2. Although the data set is small, the decline in abundance is statistically significant using both linear and exponential regression models. 3. Three factors appear to have contributed to reduce monarch abundance: degradation of the forest in the overwintering areas; the loss of breeding habitat in the United States due to the expansion ofGM herbicide-resistant crops, with consequent loss of milkweed host plants, as well as continued land development; and severe weather. 4. This decline calls into question the long-term survival of the monarchs' migratory phenomenon

Habitat↗

Sample Tube Sealing for Future Proposed Mars Sample Return Missions

A key premise of a proposed Sample Caching Rover, a crucial element of the proposed Mars Sample Return (MSR) campaign, is that the samples could be packaged and left on Mars for an extended period of time (at least five Mars years) without loss of scientific value (Fig. 1). The MEPAG E2E-iSAG (2011) concluded that the single most important factor in preserving the scientific integrity of the samples during the interval between their collection and their analysis is effective sealing of the samples.

sample integrity↗

Cumulative Interference to Aircraft Radios from Multiple Portable Electronic Devices

Cumulative interference effects from portable electronic devices (PEDs) located inside a passenger cabin are conservatively estimated for aircraft radio receivers. PEDs' emission powers in an aircraft radio frequency band are first scaled according to their locations' interference path loss (IPL) values, and the results are summed to determine the total interference power. The multiple-equipment-factor (MEF) is determined by normalizing the result against the worst case contribution from a single device. Conservative assumptions were made and MEF calculations were performed for Boeing 737's Localizer, Glide-slope, Traffic Collision Avoidance System, and Very High Frequency Communication radio systems where full-aircraft IPL data were available. The results show MEF for the systems to vary between 10 and 14 dB. The same process was also used on the more popular window/door IPL data, and the comparison show the multiple-equipment-factor results came within one decibel (dB) of each other.

Nguyen, Truong X.↗

Small Scale Mass Flow Plug Calibration

A simple control volume model has been developed to calculate the discharge coefficient through a mass flow plug (MFP) and validated with a calibration experiment. The maximum error of the model in the operating region of the MFP is 0.54%. The model uses the MFP geometry and operating pressure and temperature to couple continuity, momentum, energy, an equation of state, and wall shear. Effects of boundary layer growth and the reduction in cross-sectional flow area are calculated using an in- integral method. A CFD calibration is shown to be of lower accuracy with a maximum error of 1.35%, and slower by a factor of 100. Effects of total pressure distortion are taken into account in the experiment. Distortion creates a loss in flow rate and can be characterized by two different distortion descriptors.

mass-flow measurements↗

TPSAS-NF1676L-18905-DND

Aircraft loss of control is a leading cause of fatal accidents across all transport airplane and operational classes. Aircraft loss-of-control (LOC) accidents are highly complex in that they can result from numerous causal and contributing factors acting alone or (more often) in combination. Hence, there is no single intervention strategy to prevent these accidents. This presentation will define LOC as a dynamics and control problem, summarize LOC accident analysis results, and discuss current NASA research that supports a holistic approach for significantly reducing aircraft LOC accidents for current and future aircraft. The approach includes onboard systems technologies for LOC prevention and recovery, as well as a parallel effort for their validation. The onboard systems technologies provide improved situational awareness, guidance, and control under realistic LOC hazards, and include: hazards effects detection and mitigation; upset detection, prevention and recovery; and multiple hazards mitigation. Validation technologies include analytical, simulation, and experimental methods, tools and testbeds as well as the development of a comprehensive set of realistic LOC test scenarios. Future research directions will also be discussed.

Christine Belcastro↗

Validation and Verification (V&V) of Safety-Critical Systems Operating Under Off-Nominal Conditions

Loss of control (LOC) remains one of the largest contributors to aircraft fatal accidents worldwide. Aircraft LOC accidents are highly complex in that they can result from numerous causal and contributing factors acting alone or more often in combination. Hence, there is no single intervention strategy to prevent these accidents. Research is underway at the National Aeronautics and Space Administration (NASA) in the development of advanced onboard system technologies for preventing or recovering from loss of vehicle control and for assuring safe operation under off-nominal conditions associated with aircraft LOC accidents. The transition of these technologies into the commercial fleet will require their extensive validation and verification (V&V) and ultimate certification. The V&V of complex integrated systems poses highly significant technical challenges and is the subject of a parallel research effort at NASA. This chapter summarizes the V&V problem and presents a proposed process that could be applied to complex integrated safety-critical systems developed for preventing aircraft LOC accidents. A summary of recent research accomplishments in this effort is referenced.

Belcastro, Christine M.↗

Communication Research in Aviation and Space Operations: Symptoms and Strategies of Crew Coordination

The day-to-day operators of today's aerospace systems work under increasing pressures to accomplish more with less. They work in operational systems which are complex, technology-based, and high-risk; in which incidents and accidents have far-reaching and costly consequences. For these and other reasons, there is concern that the safety net formerly built upon redundant systems and abundant resources may become overburdened. Although we know that human ingenuity can overcome incredible odds, human nature can also fail in unpredictable ways. Over the last 20 years, a large percentage of aviation accidents and incidents have been attributed to human errors rather than hardware or environmental factors alone. A class of errors have been identified which are not due to a lack of individual, technical competencies. Rather, they are due to the failure of teams to utilize readily available resources or information in a timely fashion. These insights began a training revolution in the aviation industry called Cockpit Resource Management, which later became known as Crew Resource Management (CRM) as its concepts and applications extended to teams beyond the flightdeck. Then, as now, communication has been a cornerstone in CRM training since crew coordination and resource management largely resides within information transfer processes--both within flightcrews, and between flightcrews and the ground operations teams that support them. The research I will describe takes its roots in CRM history as we began to study communication processes in order to discover symptoms of crew coordination problems, as well as strategies of effective crew management. On the one hand, communication is often the means or the tool by which team members manage their resources, solve problems, maintain situational awareness and procedural discipline. Conversely, it is the lack of planning and resource management, loss of vigilance and situational awareness, and non-standard communications that are implicated in accidents and incidents. NASA/Ames Crew Factors researchers have been developing a model of effective crew coordination in order to understand the sources of performance breakdowns, and to develop effective solutions and interventions. Because communication is a primary mechanism by which information is received and transmitted, and because it is observable behavior, we focus on these group processes in order to identify patterns of communication that distinguish effective from less effective crew performance. Since a prime objective is to develop training recommendations for enhancing communication skills, we interpret our findings in the context of relevant task and environmental conditions, role and procedural constraints, and the normal real-time parameters of flight operations. Another research objective is to consider how communication and coordination can be enhanced through design. For example, flight deck and hardware design as well as procedural and software design may greatly influence the efficiency with which crews communicate and coordinate their work. In addition, teams and tasks may be designed, organized, and trained so that team interactions with each other are based upon appropriately shared knowledge, procedures and situation awareness. In short, we are interested in enhancing communication practices through (1) the training of specific communication skills, and (2) the design of equipment, tasks, procedures, and teams that optimize smooth, unambiguous communication processes. Two examples of communication research will be described; one in aviation and one in space operations. The first example is a high-fidelity full mission simulation study which investigates the affect of flightdeck automation on crew coordination and communication (contrasting crew performance in the DC-9 vs. MD88). Additional information is contained in the original extended abstract.

Kanki, Barbara G.↗

Constraining Arctic Climate Projections of Wintertime Warming With Surface Turbulent Flux Observations and Representation of Surface-Atmosphere Coupling

The drivers of rapid Arctic climate change—record sea ice loss, warming SSTs, and a lengthening of the sea ice melt season—compel us to understand how this complex system operates and use this knowledge to enhance Arctic predictability. Changing energy flows sparked by sea ice decline, spotlight atmosphere-surface coupling processes as central to Arctic system function and its climate change response. Despite this, the representation of surface turbulent flux parameterizations in models has not kept pace with our understanding. The large uncertainty in Arctic climate change projections, the central role of atmosphere-surface coupling, and the large discrepancy in model representation of surface turbulent fluxes indicates that these processes may serve as useful observational constraints on projected Arctic climate change. This possibility requires an evaluation of surface turbulent fluxes and their sensitivity to controlling factors (surface-air temperature and moisture differences, sea ice, and winds) within contemporary climate models (here Coupled Model Intercomparison Project 6). The influence of individual controlling factors and their interactions is diagnosed using a multi-linear regression approach. This evaluation is done for four sea ice loss regimes, determined from observational sea ice loss trends, to control for the confounding effects of natural variability between models and observations. The comparisons between satellite- and model-derived surface turbulent fluxes illustrate that while models capture the general sensitivity of surface turbulent fluxes to declining sea ice and to surface-air gradients of temperature and moisture, substantial mean state biases exist. Specifically, the central Arctic is too weak of a heat sink to the winter atmosphere compared to observations, with implications to the simulated atmospheric circulation variability and thermodynamic profiles. Models were found to be about 50% more efficient at turning an air-sea temperature gradient anomaly into a sensible heat flux anomaly relative to observations. Further, the influence of sea ice concentration on the sensible heat flux is underestimated in models compared to observations. The opposite is found for the latent heat flux variability in models; where the latent heat flux is too sensitive to a sea ice concentration anomaly. Lastly, the results suggest that present-day trends in sea ice retreat regions may serve as suitable observational constraints of projected Arctic warming.

turbulent fluxes↗

Cloning the promoter for transforming growth factor-beta type III receptor. Basal and conditional expression in fetal rat osteoblasts

Transforming growth factor-beta binds to three high affinity cell surface molecules that directly or indirectly regulate its biological effects. The type III receptor (TRIII) is a proteoglycan that lacks significant intracellular signaling or enzymatic motifs but may facilitate transforming growth factor-beta binding to other receptors, stabilize multimeric receptor complexes, or segregate growth factor from activating receptors. Because various agents or events that regulate osteoblast function rapidly modulate TRIII expression, we cloned the 5' region of the rat TRIII gene to assess possible control elements. DNA fragments from this region directed high reporter gene expression in osteoblasts. Sequencing showed no consensus TATA or CCAAT boxes, whereas several nuclear factors binding sequences within the 3' region of the promoter co-mapped with multiple transcription initiation sites, DNase I footprints, gel mobility shift analysis, or loss of activity by deletion or mutation. An upstream enhancer was evident 5' proximal to nucleotide -979, and a silencer region occurred between nucleotides -2014 and -2194. Glucocorticoid sensitivity mapped between nucleotides -687 and -253, whereas bone morphogenetic protein 2 sensitivity co-mapped within the silencer region. Thus, the TRIII promoter contains cooperative basal elements and dispersed growth factor- and hormone-sensitive regulatory regions that can control TRIII expression by osteoblasts.

Non-NASA Center↗

Linearized force representations for turbopump liquid annular seals

The analysis and the accompanying FORTRAN code, SEALPAL1, to simulate liquid annular seals with axial taper, Moody friction factors, and pre-swirl, are discussed. The output of the code includes all dynamic coefficients (stiffness, dampings, and inertias), leakage rate, torque, and horsepower loss. The computer code results were compared with five cases from the literature. The agreement was very good in almost all instances, except several predicted cross coupled stiffnesses were significantly lower than those appearing in the literature. This disagreement could reflect a theoretical or a programming error by the researcher or in the literature, or it could be a result of the difference in friction factor models or other assumptions employed.

Palazzolo, Alan B.↗

Markers of bone resorption and calcium metabolism are related to dietary intake patterns in male and female bed rest subjects

Dietary potassium and protein intakes predict net endogenous acid production in humans. Intracellular buffers, including exchangeable bone mineral, play a crucial role in balancing chronic acid-base perturbations in the body; subsequently, chronic acid loads can potentially contribute to bone loss. Bone is lost during space flight, and a dietary countermeasure would be desirable for many reasons. We studied the ability of diet protein and potassium to predict levels of bone resorption markers in males and females. Identical twin pairs (8 M, 7 F) were assigned to 2 groups: bed rest (sedentary, SED) or bed rest with supine treadmill exercise in a lower body negative pressure chamber (EX). Diet was controlled for 3 d before and 30 d of bed rest (BR). Urinary Ca, N-telopeptide (NTX), and pyridinium crosslinks (PYD) were measured before and on days 5, 12, 19, and 26 of BR. Data were analyzed by Pearson correlation (P<0.05). The ratio of dietary animal protein/potassium intake was not correlated with NTX before BR for males or females, but they were positively correlated in both groups of males during bed rest. Dietary animal protein/potassium and urine Ca were correlated before and during bed rest for the males, and only during bed rest for the females. Conversely, the ratio of dietary vegetable protein/potassium intake was negatively correlated with urinary calcium during bed rest for the females, but there was no relationship between vegetable protein/potassium intake and bone markers for the males. These data suggest that the ratio of animal protein/potassium intake may affect bone, particularly in bed rest subjects. These data show that the type of protein and gender may be additional factors that modulate the effect of diet on bone metabolism during bed rest. Altering this ratio may help prevent bone loss on Earth and during space flight.

Smith, Scott M.↗