Engineering Papers⌕ Search

SEARCH · Engineering Papers

Results for “image alignment”

Search indexed NASA NTRS and DOE OSTI research on propulsion, heat transfer, battery materials and energy systems. Follow report and document links to the original sources.

Quote a phrase for an exact phrase match. Source license links do not imply unrestricted reuse.

At least 613 records · Page 34
All sourcesNASA NTRSDOE OSTI
NASA NTRS2018

Imaging Technique for High Precision Measurement of Detector Stability for the Ocean Color Instrument

One of the new projects by NASA to explore environmental change is the Plankton, Aerosol, Cloud, ocean Ecosystem (PACE) spacecraft. The primary instrument aboard the PACE spacecraft is the Ocean Color Instrument (OCI), an advanced optical spectrometer that will measure the color of the ocean from the ultraviolet to shortwave infrared range for the purpose of observing and monitoring ocean and coastal biology. As part of the optical alignment testing that must be completed before the instrument is built, the measurement stability of the detectors at space flight operating temperatures must be determined to ensure alignment is maintained. Therefore, this project focuses on the development of an imaging technique that adheres to testing requirements and can be used to determine the stability of the OCI detector. The movements of targets affixed to a high-precision stage were analyzed through an image processing program to test the ability of the imaging technique to detect very small (under 10 micrometers) movements. It was found that movements as small as half a pixel (~6 microns) and 1 pixel (~12 microns) were able to be accurately and consistently detected with this imaging technique. This project found that the designed image analysis technique fulfills testing and measurement requirements and will be an effective metrology technique for the OCI detector stability test.

Optics↗
DOE OSTI2013

Correlating Elastic Properties and Molecular Organization of an Ionic Organic Nanostructure

Mechanical and structural properties of ionically self-assembled nanostructures of meso-tetra(4-sulfonatophenyl)porphyrin (TSPP) and meso-tetra(4-pyridyl)porphyrin (TPyP) are presented. This is the first time that elastic modulus of an ionic porphyrin nanostructure has been reported. X-ray photoelectron spectroscopy (XPS), UV-visible spectra, and elemental analysis all support a stoichiometric 1 : 1 TSPP to TPyP composition. Atomic force microscopy (AFM) revealed that the porphyrin nanostructure is composed of stacked ribbons about 20 nm tall, 70 nm wide, and several microns in length. High resolution transmission electron microscopy (HRTEM) images showed clear lattice fringes 1.5 ± 0.2 nm in width aligned along the length of the nanorod. Selected area electron diffraction (SAED) and powder X-ray diffraction patterns of TSPP:TPyP are consistent with an orthorhombic system and space group Imm2 with lattice parameters a ¼ 26.71 °A, b ¼ 20.16 °A, and c ¼ 8.61 °A. Crystallographic data is consistent with an arrangement of alternating face-to-face TSPP and TPyP molecules forming ordered columns along the length of the nanorods. The structural integrity of the solid is attributed to combined noncovalent interactions that include ionic, hydrogen bonding, and p–p interactions. The values of Young’s modulus obtained for the crystalline TSPP:TPyP nanorods averaged 6.5 ± 1.3 GPa. This modulus is comparable to those reported for covalently bonded flexible polymeric systems. The robust bonding character of the TSPP:TPyP nanostructures combined with their mechanical properties makes them excellent candidates for flexible optoelectronic devices.

36 MATERIALS SCIENCE↗
DOE OSTI2021

Dynamics of filaments during the edge-localized mode crash on NSTX

Edge localized modes (ELMs) are routinely observed in H-mode plasma regimes of the National Spherical Torus Experiment (NSTX). Due to the explosive nature of the instability, only diagnostics with high temporal and spatial resolution could provide a detailed insight into the dynamics associated with the ELMs. Gas-puff imaging at NSTX provides 2D measurements of the magnetic field aligned fluctuations (e.g., ELM filaments) in the scrape-off layer and at the plasma edge with 2.5 μs temporal and 10 mm optical resolution. A novel analysis technique was developed to estimate the frame-by-frame velocities and the spatial parameters of the dominant structures associated with the ELMs. The analysis was applied to single ELM events to characterize the ELM crash dynamics and then extended to a database of 159 ELM events. Statistical analysis was performed in order to find the characterizing dynamics of the ELM crash. The results show that on average, an ELM crash consists of a filament with a circular cross section, which is propelled outward with a characterizing peak radial velocity of ~3.3 km/s. The radial velocity was found to be linearly dependent on the distance of the filament from the separatrix, which has never been seen before. The ELM filament is characterized by propagation in the ion-diamagnetic direction poloidally with a peak velocity of 11.4 km/s. The ELM crash lasts for approximately 100 μs until the radial propulsion settles back to the pre-ELM level. Furthermore, the experimental findings were compared with analytical theory. Two possible mechanisms were identified for explaining the observations: the curvature interchange model and the current–filament interaction model.

70 PLASMA PHYSICS AND FUSION TECHNOLOGY↗
DOE OSTI2015

SU-E-T-457: Impact of Interfractional Variations On Anterior Vs. Lateral-Field Proton Therapy of Prostate Cancer

Purpose: To investigate the effects of interfractional anatomy and setup variations on plans with anterior-oblique vs. lateral beams for prostate cancer pencil beam scanning (PBS) and passive scattered (PS) proton therapy. Methods: Six patients with low/intermediate risk prostate cancer treated with PS proton therapy at our institution were selected. All patients underwent weekly verification CT scans. Implanted fiducials were used for localization, and endorectal balloons for prostate immobilization. New PBS plans with lateral beams, as well as PBS and PS plans with anterior-oblique beams (±35 deg) were created. PBS plans used two different spot sizes: ∼10mm (large) and ∼5mm (medium) sigma at 25cm range and optimized as single-field-uniform-dose with ∼8% non-uniformity. No range uncertainty margins were applied in PBS plans to maximize rectal sparing. Field-specific apertures were used when planning with large spots to sharpen the penumbrae. The planned dose was recomputed on each weekly CT with fiducials aligned to the simulation CT, scaled and accumulated via deformable image registration. Results: The dose volume analysis showed that although difference between planned and accumulated dose remains negligible for plans with conventional lateral beams using both PS and PBS, this is not the case for plans with anterior beams. The target coverage in anterior plans was largely degraded due to the variations in the beam path length and the absence of range margins. The average prostate D95 was reduced by 7.5/15.9% (using PS/PBS) after accumulation for anterior plans, compared with 0/0.4% for lateral plans. The average mean dose in organs-at-risk decreased by 1% for lateral and 2% for anterior plans, similarly for PS and PBS. Spot size did not affect the dose changes. Conclusion: Prostate plans using anterior beams may undergo clinically relevant interfractional dose degradation. Corrective strategies guided by in-vivo range measurements should be studied before clinical application of this technique.

60 APPLIED LIFE SCIENCES↗
DOE OSTI2019

Deformation Mechanisms at Grain Boundaries in Polycrystals (Final Report)

Despite its significance in polycrystalline materials, there have been few experimental investigations of the activity of grain boundary sliding (GBS) and the relationship between GBS and slip transmission at grain boundaries. This work addressed this knowledge gap by an experimental and analytical investigation into the interactions between grain boundary sliding (GBS) and slip transmission plastic deformation mechanisms, and how these are impacted by local microstructure. Polycrystalline columnar aluminum of 99.99% purity was examined as a highly modellable system for characterizing grain boundary-local deformation mechanism interaction. High-resolution, large field-of-view strain fields and grain orientation information were captured and statistically analyzed to identify deformation activity with respect to the local microstructure, using a combination of scanning electron microscopy and digital image correlation (SEM-DIC) with electron backscatter diffraction (EBSD). Alignment between the lower-resolution electron backscatter diffraction (EBSD) data and the higher-resolution strain fields was significantly improved by clustering of strain data within an EBSD-defined boundary mantle. Although this work specifically focuses on characterizing the relationship between grain boundary sliding (GBS) and slip transmission, the developed experimental approach, multimodal data alignment process, and automated displacement discontinuity measurement process can be used to study a variety of mechanism interactions across a broad range of materials. Regarding GBS and slip transmission interaction, significant findings include that (1) grain boundaries that slide easily do not facilitate slip transmission; (2) substantial gradients in GBS magnitude could be found along the length of individual grain boundaries, and these were caused by strain discontinuities across the boundary related to deformation anisotropy between adjacent grains; (3) direct transmission and GBS were anti-compatible and facilitated by opposing boundary types (low misorientation and high energy grain boundaries respectively); (4) increased GBS activity was correlated with decreased indirect transmission behavior; (5) GBS accommodation at triple junctions was enabled by intragranular plasticity; and (6) the local intragranular plastic strain discontinuity between grains determined the magnitude of GBS gradients. The experimental strain fields were compared to that of a tangent crystal plasticity finite element (CPFE) model developed by collaborators (Mr. Ajey Venkataraman and Professor Michael Sangid, Purdue University). Implication of this work for improving CPFE models and deformation prediction are discussed. This work provides insight into the nature of these mechanisms and can be used to identify strain transfer criteria that can lead to improved GBS-sensitive crystal plasticity models.

36 MATERIALS SCIENCE↗
DOE OSTI2020

Image quality indicator and dechromator setup for static LANSCE proton radiography experiment

This document describes a static geometry consisting of a sphere of gold and Ti-6Al-4V alloy, along with an energy-loss matching dechromator composed of polycarbonate, to field with the X3 electromagnetic magnifying lens at LANSCE during the next beam cycle. This static configuration will allow us to: (1) characterize the system’s resolution at the material interface between the gold and titanium alloy, and test the image quality for fine features associated with the screws used to fasten the titanium alloy hemispheres; (2) tune our models of proton scattering and imaging for these materials; and (3) test a procedure to align the polycarbonate dechromator and the sphere within the proton beamline. The data will also be suitable for validation of the software options available for proton radiography simulations.

46 INSTRUMENTATION RELATED TO NUCLEAR SCIENCE AND ↗
NASA NTRS1985

X-ray determination of parts alignment

A method for determining the alignment of adjoining metal objects is provided. The method comprises producing an X-ray image of adjoining surfaces of the two metal objects. The X-ray beam is tangential to the point the surfaces are joined. The method is particularly applicable where the alignment of the two metal objects is not readily susceptible to visual inspection.

Nelson, C. W.↗
NASA NTRS1998

STS-95 Day 07 Highlights

On this seventh day of the STS-95 mission, the flight crew, Cmdr. Curtis L. Brown, Pilot Steven W. Lindsey, Mission Specialists Scott E. Parazynski, Stephen K. Robinson, and Pedro Duque, and Payload Specialists Chiaki Mukai and John H. Glenn, again test the Orbiter Space Vision System. OSVS uses special markings on Spartan and the shuttle cargo bay to provide an alignment aid for the arm's operator using shuttle television images. It will be used extensively on the next Space Shuttle flight in December as an aid in using the arm to join together the first two modules of the International Space Station. Specialist John Glenn will complete a daily back-pain questionnaire by as part of a study of how the muscle, intervertebral discs and bone marrow change after exposure to microgravity.

Source record↗
NASA NTRS2012

Science Opportunities with the Near-IR Camera (NIRCam) on the James Webb Space Telescope (JWST)

The Near-Infrared Camera (NIRCam) on the James Webb Space Telescope (JWST) offers revolutionary gains in sensitivity throughout the 1-5 micrometer region. NIRCam will enable great advances in all areas of astrophysics, from the composition of objects in our own Kuiper Belt and the physical properties of planets orbiting nearby stars to the formation of stars and the detection of the youngest galaxies in the Universe. NIRCam also plays an important role in initial alignment of JWST and the long term maintenance of its image quality. NIRCam is presently undergoing instrument Integration and Test in preparation for delivery to the JWST project. Key near-term milestones include the completion of cryogenic testing of the entire instrument; demonstration of scientific and wavefront sensing performance requirements; testing of replacement H2RG detectors arrays; and an analysis of coronagraphic performance in light of measured telescope wavefront characteristics. This paper summarizes the performance of NIRCam, the scientific and education/outreach goals of the science team, and some results of the on-going testing program.

solar system↗
NASA NTRS2016

Development and Implementation of a Generic Analysis Template for Structural-Thermal-Optical-Performance Modeling

Performance-related effects of system level temperature changes can be a key consideration in the design of many types of optical instruments. This is especially true for space-based imagers, which may require complex thermal control systems to maintain alignment of the optical components. Structural-Thermal-Optical-Performance (STOP) analysis is a multi-disciplinary process that can be used to assess the performance of these optical systems when subjected to the expected design environment. This type of analysis can be very time consuming, which makes it difficult to use as a trade study tool early in the project life cycle. In many cases, only one or two iterations can be performed over the course of a project. This limits the design space to best practices since it may be too difficult, or take too long, to test new concepts analytically. In order to overcome this challenge, automation, and a standard procedure for performing these studies is essential. A methodology was developed within the framework of the Comet software tool that captures the basic inputs, outputs, and processes used in most STOP analyses. This resulted in a generic, reusable analysis template that can be used for design trades for a variety of optical systems. The template captures much of the upfront setup such as meshing, boundary conditions, data transfer, naming conventions, and post-processing, and therefore saves time for each subsequent project. A description of the methodology and the analysis template is presented, and results are described for a simple telescope optical system.

Scola, Salvatore↗
NASA NTRSDate not supplied

Defining Pupil Knowledge Requirements for Roman Space Telescope Integrated Payload Assembly Testing

This thesis examines the use of phase retrieval to characterize an optical system under testing conditions with pupil knowledge error. The purpose of this investigation is to define pupil knowledge requirements for the integrated payload testing of the Roman Space Telescope. We have conducted a Monte Carlo study to determine how location uncertainty of the ground support equipment relative to the payload caused by the temperature deformation in the Space Environment Simulator will affect our ability to use image-based wavefront sensing during the test to characterize system alignment. This test will be conducted with significant wavefront error (WFE) present due to gravity sag on the primary mirror. The study incrementally decenters two pieces of ground support equipment and evaluates how the phase retrieval algorithm attempts to fit the wavefront. We conducted this investigation in two steps. First, we used an ideal optical model of the test configuration without the gravity sag on the primary mirror to see the fitting effects related only to pupil knowledge error introduced by the decentering. Then, we used perturbed and gravity sag models to investigate the effects of decentering dependent wavefront effects in addition to pupil knowledge error. The results from the ideal model provided a clear limit of the amount of pupil knowledge error that can be present before seeing significant WFE in the phase retrieval. For the second study, we used the decentering tolerances from the ideal model results to determine the WFE effects of decentering in the presence of gravity sag and system misalignments. The second part of this study will be factored into the overall integrated payload assembly testing WFE budget.

Roman Space Telescope↗
NASA NTRS2022

Defining Pupil Knowledge Requirements for Roman Space Telescope Integrated Payload Assembly Testing

This thesis examines the use of phase retrieval to characterize an optical system under testing conditions with pupil knowledge error. The purpose of this research is to define pupil knowledge requirements for the integrated payload testing of the Roman Space Telescope (RST). I have conducted a Monte Carlo study to determine how uncertainty in the location of the ground support equipment relative to the payload will affect the ability to use image-based wavefront sensing during the test to characterize system alignment. This test will be conducted in the Space Environment Simulator (SES) with the presence of Wavefront Error (WFE) due to gravity sag on the primary mirror. In this study, I incrementally decentered a piece of ground support equipment, the SubAperture Metrology System (SAMS), and evaluated how the phase retrieval algorithm attempted to fit the wavefront with the pupil mismatch. The results of this study are a factor in the overall Integrated Payload Assembly (IPA) testing WFE budget.

Roman Space Telescope↗
NASA NTRS2024

Classifying Microwave Radiometer Observations Over the Netherlands Into Dry, Shallow-, and Non-Shallow Precipitation Using A Random Forest Model

Spaceborne microwave radiometers represent an important component of the Global Precipitation Measurement (GPM) mission due to their frequent sampling of rain systems. Microwave radiometers measure microwave radiation (brightness temperatures, Tb), which can be converted into precipitation estimates with appropriate assumptions. However, detecting shallow precipitation systems using space-borne radiometers is challenging, especially over land, as their weak signals are hard to differentiate from those associated with dry conditions. This study uses a random forest model (RF) to classify microwave radiometer observations as dry, shallow, or nonshallow over the Netherlands - a region with varying surface conditions and frequent occurrence of shallow precipitation. The RF is trained on five years of data (2016-2020) and tested with two independent years (2015, 2021). The observations are classified using ground-based weather radar echo top heights. Various RF models are assessed, such as using only GPM’s Microwave Imager (GMI) Tb values as input features or including spatially aligned ERA-5 2-meter temperature and freezing level reanalysis and/or Dual Precipitation Radar (DPR) observations. Independent of the input features, the model performs best in summer and worst in winter. The model classifies observations from high-frequency channels (≥85 GHz) with lower Tb-values as non-shallow, higher values as dry, and those in between as shallow. Misclassified footprints exhibit radiometric characteristics corresponding to their assigned class. Case studies reveal dry observations misclassified as shallow are associated with lower Tb-values, likely resulting from the presence of ice particles in non-precipitating clouds. Shallow footprints misclassified as dry are likely related to the absence of ice particles.

Linda Bogerd↗
NASA NTRS2005

Measuring Low-Order Aberrations in a Segmented Telescope

The in-focus PSF optimizer (IPO) is an algorithm for use in monitoring and controlling the alignment of the segments of a segmented-mirror astronomical telescope. IPO is so named because it computes wave-front aberrations of the telescope from digitized pointspread functions (PSFs) measured in infocus images. Inasmuch as distant astronomical objects that behave optically as point sources can typically be seen in almost any astronomical image, the main benefit afforded by IPO may be to enable maintenance of mirror-segment alignments without detracting from valuable scientific-observation time. IPO evolved from prescription-retrieval type algorithms. Prescription retrieval uses in-focus and out-of-focus PSFs to infer the state of an imaging optical system. The state, in this context, refers to the positions, orientations, and low-order figure errors of the optical elements in the system. Both prescription- retrieval and IPO use an iterative, nonlinear, least-squares optimizer to compute the optimal state parameters such that a digital computer-generated model image matches the digitized image acquired from the real system. The difference between IPO and prescription- retrieval algorithms is that IPO is specifically designed to utilize infocus images only. Although the restriction to in-focus images limits IPO to calculating only the lowest-order wave front aberrations, it also causes the resulting computation to take much less time because fewer degrees of freedom are included in the optimization process. In the prescription retrieval software developed at JPL, the model images are generated using the ray-trace/physical optics program, MACOS. IPO, on the other hand, uses a linear sensitivity matrix to compute the exit-pupil wave front from the system parameters; the wave front is then converted into a complex pupil field, which is then propagated to the image plane via a fast Fourier transform. This approach is computationally faster and requires less computer memory than is needed for prescription retrieval.

Ohara, Catherine↗
NASA NTRS2000

Reflective Focused Schlieren System Improved for Use in 10- by 10-Foot Supersonic Wind Tunnel

The reflective focused schlieren system that was developed for use in the 10- by 10-Foot Supersonic Wind Tunnel (10x10 SWT) at the NASA Glenn Research Center at Lewis Field as part of the Unstart Test Program was improved this past year. In April 1999, the development and use of the system was presented at the Supersonic Tunnel Association International in Bedford, England. A focused schlieren system is similar to a standard schlieren system in that shock waves coming from an object in supersonic flow can be seen using a standard video camera. Unlike the standard schlieren system, which produces a two-dimensional schlieren image, a focused schlieren system can produce a threedimensional image. The preceding drawing shows the components of the reflective focused schlieren system being developed for use in the 10x10 SWT. Although the system worked well for the Unstart Test Program, it was not sensitive enough to be classified as a facility capability. Therefore, a program was implemented to improve the sensitivity of the reflective focused schlieren system so that it could be a facility capability for Glenn's 10x10 SWT. Several techniques were implemented to increase the sensitivity and to improve the overall operation of the system. These included refinement of the source grid, improvement in the cutoff grid production, improvement of the source grid and cutoff grid alignment, installation of an improved light source, and incorporation of an image-enhancing system. These changes are being implemented with the system set up in the laboratory. A checkout test of the system is planned in the 10x10 SWT in March 2000. Of these techniques, the most developed is the refinement of the source grid. The original system had a pattern of -in. by -in. squares on -in. centers (distance between the center points of adjacent squares). This gave a ratio of light to dark (reflective to nonreflective area) of 3:1. The recommended ratio is 1:1. In order to accomplish this, a pattern of -in.-diameter dots on 3/8-in. centers was developed. Preliminary tests with this pattern showed an increase in system sensitivity and image clarity. Further testing and refinement are scheduled. The former and improved dot patterns are shown. The use of glass plates to produce the cutoff grid improved the cutoff grid's quality and helped to align it with the source grid. The cutoff grid, which is the negative of the source grid, is made by exposing photography film (or glass plates) to the proper light while it is installed in the focused schlieren system. The exposed film or plate is removed from the system and then developed as a photograph negative. Because the glass plates are rigid, they eliminate the risk of distortion when the negative is reinstalled in the system and realigned with the source grid.

Williamson, Gary Scott↗
NASA NTRS2017

Optimal Transport Based Control of Granular Imaging System in Space

"Orbiting Rainbows” is a paradigm for creating a space-based observatory (telescope) from confined and aligned granular media. The overall objective is to construct a very large and lightweight aperture in space using a cloud of micron-sized particles held in position and aligned by the application of external electromagnetic fields, thus alleviating the extreme expense of deploying and stabilizing large monolithic telescopes by reducing the mass of the primary aperture. Adaptive optics techniques for wavefront stabilization and computational imaging techniques are then used to remove the optical noise from the scattering reflections of the granular medium, and finally producing clean images within the diffraction limit. In this paper, we address one of the key challenges of this new paradigm, namely controlling the position and orientation of the granules or particles so that the cloud of particles achieves the desired shape of an ultra-lightweight telescope and points into the right orientation. A further complication arises due to the fact that the particles do not have any onboard actuators. A number of external electric-field-based actuators are used to control all the particles simultaneously. Moreover, the number of actuators are orders-of-magnitude smaller than the number of particles, making this system largely under-actuated. Since the cloud of particles in any plausible configuration can be modeled as a probability distribution over the workspace, we formulate this control challenge as an optimal transport problem and then show that our optimal transport based control law drives the cloud of particles from any initial distribution to the desired position distribution (optical surface) and angular distribution (polarization state). Simulation results demonstrate the effectiveness of our approach.

Bandyopadhyay, Saptarshi↗
DOE OSTI2016

A Closed-Loop Proportional-Integral (PI) Control Software for Fully Mechanically Controlled Automated Electron Microscopic Tomography

A closed-loop proportional-integral (PI) control software is provided for fully mechanically controlled automated electron microscopic tomography. The software is developed based on Gatan DigitalMicrograph, and is compatible with Zeiss LIBRA 120 transmission electron microscope. However, it can be expanded to other TEM instrument with modification. The software consists of a graphical user interface, a digital PI controller, an image analyzing unit, and other drive units (i.e.: image acquire unit and goniometer drive unit). During a tomography data collection process, the image analyzing unit analyzes both the accumulated shift and defocus value of the latest acquired image, and provides the results to the digital PI controller. The digital PI control compares the results with the preset values and determines the optimum adjustments of the goniometer. The goniometer drive unit adjusts the spatial position of the specimen according to the instructions given by the digital PI controller for the next tilt angle and image acquisition. The goniometer drive unit achieves high precision positioning by using a backlash elimination method. The major benefits of the software are: 1) the goniometer drive unit keeps pre-aligned/optimized beam conditions unchanged and achieves position tracking solely through mechanical control; 2) the image analyzing unit relies on only historical data and therefore does not require additional images/exposures; 3) the PI controller enables the system to dynamically track the imaging target with extremely low system error.

Ren, Gang↗
DOE OSTI2014

Interfraction Displacement of Primary Tumor and Involved Lymph Nodes Relative to Anatomic Landmarks in Image Guided Radiation Therapy of Locally Advanced Lung Cancer

Purpose: To analyze primary tumor (PT) and lymph node (LN) position changes relative to each other and relative to anatomic landmarks during conventionally fractionated radiation therapy for patients with locally advanced lung cancer. Methods and Materials: In 12 patients with locally advanced non-small cell lung cancer PT, LN, carina, and 1 thoracic vertebra were manually contoured on weekly 4-dimensional fan-beam CT scans. Systematic and random interfraction displacements of all contoured structures were identified in the 3 cardinal directions, and resulting setup margins were calculated. Time trends and the effect of volume changes on displacements were analyzed. Results: Three-dimensional displacement vectors and systematic/random interfraction displacements were smaller for carina than for vertebra both for PT and LN. For PT, mean (SD) 3-dimensional displacement vectors with carina-based alignment were 7 (4) mm versus 9 (5) mm with bony anatomy (P<.0001). For LN, smaller displacements were found with carina- (5 [3] mm, P<.0001) and vertebra-based (6 [3] mm, P=.002) alignment compared with using PT for setup (8 [5] mm). Primary tumor and LN displacements relative to bone and carina were independent (P>.05). Displacements between PT and bone (P=.04) and between PT and LN (P=.01) were significantly correlated with PT volume regression. Displacements between LN and carina were correlated with LN volume change (P=.03). Conclusions: Carina-based setup results in a more reproducible PT and LN alignment than bony anatomy setup. Considering the independence of PT and LN displacement and the impact of volume regression on displacements over time, repeated CT imaging even with PT-based alignment is recommended in locally advanced disease.

62 RADIOLOGY AND NUCLEAR MEDICINE↗