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At least 613 records · Page 34

Improved Safety Injection Flow Map Associated with Target RCS Depressurization to Maintain Core Coolability of OPR1000

In Korea, Severe Accident Management Guidance (SAMG) for Optimized Power Reactor (OPR1000) has been developed through the research results related to the WOG SAMG, in which the operation phase shifts from the Emergency Operation Procedure (EOP) to the SAMG when the Core Exit Temperature (CET) reaches 923 K. Among 7 mitigation strategies envisioned, the third management strategy, injecting coolant into Reactor Coolant System (RCS) by depressurizing the RCS is one of the key strategies to fortify the in-vessel retention capability. As an aid to such mitigation strategy, a safety injection (SI) flow map has been developed by Lee et al. for predicting required flow rate associated with target RCS depressurization to recover in-vessel coolability. The mechanistic SI flow map used the CET increase rate and core water level decrease rate obtained from MELCOR code simulation. It should be noted that during the severe accident, the total heat generated is sum of the decay heat and the oxidation heat. Thus, it is necessary to consider additional heat sources by oxidation reaction between cladding, structure, control rod, and hot steam prior to the injection of coolant. It was believed that the SI model estimated required flow rate rather conservatively by considering the expected amount decay heat and the accumulated heat in the core based on the RCS pressure. However, it was confirmed that the SI model developed by Lee et al. could not represent the total heat removal especially since start of oxidation. Under transient conditions, the heat sources accumulated in the heat structures (fuel, cladding, supporting structures) should be embarked in the model for accurate contribution of the total heat source to the required flow rate. Therefore, the objective of this study is to improve the previous SI flow map predicting the injection flow rate associated with target RCS depressurization to satisfy the in-vessel coolability during severe accidents. Additional terms were developed to reflect accurate heat accumulating and included in the existing model. Resulting SI flow map includes the target RCS depressurization, which enables discharge of the required flow rate by utilizing the flow rate-pressure curve with operation of two high pressure safety injections (HPSIs). Also recent MELCOR simulation result of a postulated steam generator tube rupture (SGTR) accident verified the accuracy of the improved map.

11 NUCLEAR FUEL CYCLE AND FUEL MATERIALS↗

Data for The Value of Reversible Carbon Storage in a Zero-Emissions World

Atmospheric carbon dioxide removal (CDR) is required to stabilize global temperature. CDR can be achieved via ecosystem-based approaches that are cost-effective but reversible (e.g., soil and forest management) or by more durable but expensive approaches (e.g., direct air capture coupled with geologic storage). Here, we examine trade-offs between these approaches, focusing on timing, climate impacts, and cost. We simulated reversible carbon accrual for a range of CDR contract structures using a general minimalist model of ecosystem carbon cycling, and parameterized it to simulate US agricultural soil management─specifically cover cropping─as a case study. We then quantified the resulting impact on atmospheric carbon and global temperature using a climate model emulator. We find that maintaining a patchwork of reversible CDR projects by replacing lapsed projects with new projects can reduce warming by 22–195 μ°C in 2100 and that the magnitude of this cooling effect depends on how effectively the patchwork is maintained. Long-term maintenance of reversible CDR projects requires institutional stability that cannot be guaranteed over multiple decades. Consequently, effective CDR ultimately requires replacing reversible projects with durable projects. To address this problem, we modeled the cost of replacing reversible agricultural soil CDR with geologic CDR. We found that using reversible CDR as a bridge to durable CDR is potentially more cost-effective as a global cooling strategy (0.20–0.81 billion USD per μ°C avoided) than perpetual maintenance of reversible CDR (0.32–1.31 billion USD per μ°C avoided) or an immediate transition to durable CDR (1.37–2.19 billion USD per μ°C avoided). However, we emphasize that institutional commitments to maintain reversible CDR projects cannot be guaranteed. Reliance on reversible CDR as a bridge to durable CDR therefore carries an unknown amount of risk and will only function if efforts to maintain reversible CDR are robust.

Carbon↗

Socially Driven HVAC Optimization Federal Building and US Courthouse Phoenix, Arizona

Under many circumstances in facilities management, keeping occupants comfortable and saving energy are diametrically opposed. To stay cool in summer and warm in winter requires energy to maintain indoor temperatures. If energy is saved by allowing indoor temperatures to get warmer in the summer or colder in winter, occupants’ comfort levels decrease. There is great potential to reduce costs and maintain occupant comfort if a system existed that could break this diametric opposition. The comfort of building occupants in today’s facilities is controlled by maintaining a given space temperature through the use of a thermostat. These devices operate in a very simple manner in which they are set to maintain a certain constant space temperature range. If the occupant is too hot or cold, he or she writes a work order for facility maintenance staff to adjust the thermostat to a new constant temperature range. This feedback cycle is repeated as needed to avoid generating complaints of too hot/cold from the occupants. This system has two areas in which it can be improved. First, there is the labor cost associated with a facilities maintenance person having to respond to each request when an occupant is uncomfortable. Person-hours are spent receiving the work order and adjusting space thermostats to a level that, hopefully, will allow the occupant to be comfortable. Second, the space temperature is maintained within a constant range, with no effort being made to finetune the space temperature to a setting that conserves energy while maintaining occupant comfort. Occupant comfort is based upon many more factors than just the space temperature. When other factors are taken into account, there is potential to save energy while maintaining that comfort level.

32 ENERGY CONSERVATION, CONSUMPTION, AND UTILIZATI↗

In vivo evaluation of an adaptive resuscitation controller using whole blood and crystalloid infusates for hemorrhagic shock

Introduction Hemorrhage remains the leading cause of preventable death on the battlefield. The most effective means to increase survivability is early hemorrhage control and fluid resuscitation. Unfortunately, fluid resuscitation requires constant adjustments to ensure casualty is properly managed, which is often not feasible in the pre-hospital setting. In this study, we showed how an adaptive closed-loop controller for hemorrhage resuscitation can be used to automate hemodynamic management using a swine hemorrhagic shock injury model. Methods The adaptive resuscitation controller (ARC) was previously developed to track pressure–volume responsiveness in real time and adjust its infusion rate to reach the target mean arterial pressure (MAP). Swine while maintained under a surgical plane of anesthesia and analgesia underwent a splenectomy, followed by two hemorrhage and resuscitation events. For the first resuscitation event, hemorrhage was induced to reduce the MAP to 35 mmHg until arterial lactate reached 4 mmol/L. The ARC system then infused whole blood (WB) to reach the target MAP and maintained the subject using crystalloids for 120 min. For the second resuscitation event, the subjects were hemorrhaged again but resuscitated using only crystalloid infusion to reach the target MAP and 120-min maintenance. Results The ARC was effective at WB resuscitation, reaching the target MAP in 2.0 ± 1.0 min. The median performance error was 1.1% ± 4.6%, and target overshoot was 14.4% ± 7.0% of the target MAP. The ARC maintained all animals throughout the 120 min maintenance period. For the second crystalloid-based resuscitation, ARC required a longer time to reach the target MAP, at an average rise time of 4.3 ± 4.0 min. However, target overshoot was reduced to 8.4% ± 7.3% of the target MAP. Much higher flow rates were required to maintain the target MAP during the second resuscitation event than during the first resuscitation event. Discussion The ARC was able to rapidly reach and maintain the target MAP effectively. However, this sometimes required large volumes of fluid as the ARC’s only goal was to reach the target MAP. Further clinical insight is needed regarding the preferred aggression level to achieve the target MAP. In conclusion, the ARC was successful in its programmed objective of reaching and maintaining the target MAP for extended periods of time in vivo , a critical next step toward improving hemorrhage treatment in the pre-hospital environment.

Snider, Eric J.↗

Excercise Within LBNP as an Artificial Gravity Countermeasure

Previous exercise in space has lacked sufficient loads to maintain preflight cardiovascular and musculoskeletal mass and function. Lower body negative pressure (LBNP) produces a static force equivalent to one Earth body weight by each 52 mm Hg of LBNP during supine posture. LBNP also provides transmural blood pressures simulating upright exercise. Thus, this artificial-gravity concept may help maintain cardiovascular and musculoskeletal systems of crewmembers during prolonged exposure to microgravity. Currently available, bungee cord assisted, treadmill exercise is limited by harness discomfort, lower than normal loads, abnormal post-flight gait, and the absence of gravitational blood pressures within the vascular system. PURPOSE: This project evaluates a method to create artificial gravity using supine LBNP treadmill exercise to prevent loss of physiologic function in microgravity simulated by 30 days of bed rest. Identical twins were used as volunteers so that statistical power could be maximized. This countermeasure is being transitioned to space flight. CURRENT STATUS OF RESEARCH Methods: Six sets of identical twins (6 females and 14 males, 21-36 years) remained in 6 head-down tilt (HDT) bed rest for 30 days to simulate prolonged microgravity. Six subjects were randomly selected to exercise supine in an LBNP chamber for 40 minutes six days per week (EX group), while their twin brothers served as non-exercise controls (CON). Pressure within the exercise LBNP chamber was adjusted to increase load, hence increasing exercise intensity. During supine treadmill exercise, LBNP (52-63 mmHg) was applied to produce foot ward forces equivalent to those for upright running on Earth at 1.0-1.2 times body weight (BW) and subjects performed an interval exercise protocol (40-80% peak exercise capacity [VO2pk]). Five minutes of resting LBNP immediately followed each exercise session. Results: Orthostatic tolerance time decreased significantly after 30 days bed rest in the CON group, but was relatively maintained in the EX group. VO2pk was maintained in EX males, but not in CON males. Isokinetic knee strength (extension, peak torque) decreased significantly in CON males, but was preserved in EX males. The EX group had significantly higher spine muscle strength after bed rest than the CON group. The cross-sectional area of spinal muscle at L4/5 level decreased significantly in the CON group but not in the EX group. Urinary n-telopeptide excretion, an index of bone resorption, was increased during bed rest in CON, but not in EX subjects. This suggests protection by LBNP exercise against the increase in bone resorption typically seen in simulated and actual microgravity. Significant changes in bone mineral density (BMD) in the spine and ribs were observed in CON subjects, but not in EX subjects. Conclusions: Our treadmill exercise protocol within LBNP plus a short period of post-exercise LBNP maintains orthostatic responses, upright exercise capacity and other important physiologic parameters during bed rest. These results document the efficacy of our apparatus and exercise protocol for maintaining physiologic structure and function during long-duration microgravity as simulated by 30 days of HDT bed rest. FUTURE PLANS: More sets of female identical twins are needed to reach significance. The LBNP exercise chamber will be redesigned for flight.

Hargens, A. R.↗

Thermal Performance of ATLAS Laser Thermal Control System Demonstration Unit

The second Ice, Cloud, and Land Elevation Satellite mission currently planned by National Aeronautics and Space Administration will measure global ice topography and canopy height using the Advanced Topographic Laser Altimeter System {ATLAS). The ATLAS comprises two lasers; but only one will be used at a time. Each laser will generate between 125 watts and 250 watts of heat, and each laser has its own optimal operating temperature that must be maintained within plus or minus 1 degree Centigrade accuracy by the Laser Thermal Control System (LTCS) consisting of a constant conductance heat pipe (CCHP), a loop heat pipe (LHP) and a radiator. The heat generated by the laser is acquired by the CCHP and transferred to the LHP, which delivers the heat to the radiator for ultimate rejection. The radiator can be exposed to temperatures between minus 71 degrees Centigrade and minus 93 degrees Centigrade. The two lasers can have different operating temperatures varying between plus 15 degrees Centigrade and plus 30 degrees Centigrade, and their operating temperatures are not known while the LTCS is being designed and built. Major challenges of the LTCS include: 1) A single thermal control system must maintain the ATLAS at 15 degrees Centigrade with 250 watts heat load and minus 71 degrees Centigrade radiator sink temperature, and maintain the ATLAS at plus 30 degrees Centigrade with 125 watts heat load and minus 93 degrees Centigrade radiator sink temperature. Furthermore, the LTCS must be qualification tested to maintain the ATLAS between plus 10 degrees Centigrade and plus 35 degrees Centigrade. 2) The LTCS must be shut down to ensure that the ATLAS can be maintained above its lowest desirable temperature of minus 2 degrees Centigrade during the survival mode. No software control algorithm for LTCS can be activated during survival and only thermostats can be used. 3) The radiator must be kept above minus 65 degrees Centigrade to prevent ammonia from freezing using no more than 135 watts of heater power. 4) The LHP reservoir control heater power is limited to 15 watts with a 70 percent duty cycle. 5) The voltage of the power supply can vary between 26 volts direct current and 34 volts direct current during the spacecraft lifetime. A design analysis shows that a single LTCS can satisfy these requirements. However, shutdown of· the LHP is particularly challenging and the shutdown heater must be wired in series with two reservoir thermostats and two CCHP thermostats at different set points. An LTCS demonstration unit has been tested to verify these performance characteristics experimentally prior to proceeding to the final LTCS design and fabrication. Test results showed that the LHP shutdown scheme would be able to shut down the LHP as designed and the reservoir control heater can maintain the ATLAS mass simulator within the plus or minus 1 degrees Centigrade accuracy under various combinations of the heat load, sink temperature, and power supply voltage.

Ku, Jentung↗

An Experimental Investigation of Fuel Staging In A Model Gas Turbine Combustor

Modern gas turbine engines are typically operated in a lean-premixed configuration in order to meet emissions requirements. Lean operation makes gas turbines more susceptible to combustion instability, which can cause catastrophic hardware failure if left unchecked. The spatially uneven distribution of fuel in a gas turbine combustor, known as fuel staging, is an effective way of suppressing instabilities. This dissertation examines the effect of both steady-state and transient fuel-staging in a model gas turbine combustor. First, the steady-state effect of fuel staging on nominally unstable operating conditions is examined. At 200 degrees Celsius and a bulk flow velocity of 26 m/s, the combustor undergoes self-excited instabilities when the equivalence ratio is between φ = 0.70 and φ = 0.74 when all nozzles are fueled equally. These instabilities are suppressed when the center nozzle equivalence ratio is increased to φ Staging = 0.85 and the outer nozzle equivalence ratio maintained at φ = 0.70 or when the global equivalence ratio is maintained at φ = 0.70 by increasing the center nozzle equivalence ratio to φ Staging = 0.74 and decreasing the outer nozzle equivalence ratio to φ Staging = 0.69. The staged p' RMS amplitudes are found to decrease with increasing equivalence ratio and the damping rates found to increase with increasing equivalence ratio. Next, axisymmetric fuel staging transients are conducted valve opening/closing timescales of 1, 16, 58, 4,000, and 10,000 ms, and equivalence ratios of φ staging = 0.75, 0.80, 0.85. It should be noted that these valve opening/closing timescales, referred to as τ Transient , differ from the actual fuel convection timescale that are summarized in Table 5.2. It is found that the combustor pressure fluctuation at the end of the transient strongly depends on staging equivalence ratio but not on τ Transient . Increasing the staging equivalence ratio decreased the staged- stable combustor pressure amplitude, similarly to the steady-state results. The staged-stable damping rate trends are insensitive to to τ Transient and increased with increasing staging equivalence ratio. The timescale of the transition, τ, is found to be sensitive to both τ Transient and the staging equivalence ratio. For a Modern gas turbine engines are typically operated in a lean-premixed configuration in order to meet emissions requirements. Lean operation makes gas turbines more susceptible to combustion instability, which can cause catastrophic hardware failure if left unchecked. The spatially uneven distribution of fuel in a gas turbine combustor, known as fuel staging, is an effective way of suppressing instabilities. This dissertation examines the effect of both steady-state and transient fuel-staging in a model gas turbine combustor. First, the steady-state effect of fuel staging on nominally unstable operating conditions is examined. At 200 degrees Celsius and a bulk flow velocity of 26 m/s, the combustor undergoes self-excited instabilities when the equivalence ratio is between φ = 0.70 and φ = 0.74 when all nozzles are fueled equally. These instabilities are suppressed when the center nozzle equivalence ratio is increased to φ Staging = 0.85 and the outer nozzle equivalence ratio maintained at φ = 0.70 or when the global equivalence ratio is maintained at φ = 0.70 by increasing the center nozzle equivalence ratio to φ Staging = 0.74 and decreasing the outer nozzle equivalence ratio to φ Staging = 0.69. The staged p' RMS amplitudes are found to decrease with increasing equivalence ratio and the damping rates found to increase with increasing equivalence ratio. Next, axisymmetric fuel staging transients are conducted valve opening/closing timescales of 1, 16, 58, 4,000, and 10,000 ms, and equivalence ratios of φ staging = 0.75, 0.80, 0.85. It should be noted that these valve opening/closing timescales, referred to as τ Transient , differ from the actual fuel convection timescale that are summarized in Table 5.2. It is found that the combustor pressure fluctuation at the end of the transient strongly depends on staging equivalence ratio but not on τ Transient . Increasing the staging equivalence ratio decreased the staged-stable combustor pressure amplitude, similarly to the steady-state results. The staged-stable damping rate trends are insensitive to to τ Transient and increased with increasing staging equivalence ratio. The timescale of the transition, τ, is found to be sensitive to both τ Transient and the staging equivalence ratio. For a Modern gas turbine engines are typically operated in a lean-premixed configuration in order to meet emissions requirements. Lean operation makes gas turbines more susceptible to combustion instability, which can cause catastrophic hardware failure if left unchecked. The spatially uneven distribution of fuel in a gas turbine combustor, known as fuel staging, is an effective way of suppressing instabilities. This dissertation examines the effect of both steady-state and transient fuel-staging in a model gas turbine combustor. First, the steady-state effect of fuel staging on nominally unstable operating conditions is examined. At 200 degrees Celsius and a bulk flow velocity of 26 m/s, the combustor undergoes self-excited instabilities when the equivalence ratio is between φ = 0.70 and φ = 0.74 when all nozzles are fueled equally. These instabilities are suppressed when the center nozzle equivalence ratio is increased to φ Staging = 0.85 and the outer nozzle equivalence ratio maintained at φ = 0.70 or when the global equivalence ratio is maintained at φ = 0.70 by increasing the center nozzle equivalence ratio to φ Staging = 0.74 and decreasing the outer nozzle equivalence ratio to φ Staging = 0.69. The staged p' RMS amplitudes are found to decrease with increasing equivalence ratio and the damping rates found to increase with increasing equivalence ratio. Next, axisymmetric fuel staging transients are conducted valve opening/closing timescales of 1, 16, 58, 4,000, and 10,000 ms, and equivalence ratios of φ staging = 0.75, 0.80, 0.85. It should be noted that these valve opening/closing timescales, referred to as τ Transient , differ from the actual fuel convection timescale that are summarized in Table 5.2. It is found that the combustor pressure fluctuation at the end of the transient strongly depends on staging equivalence ratio but not on τ Transient . Increasing the staging equivalence ratio decreased the staged- stable combustor pressure amplitude, similarly to the steady-state results. The staged-stable damping rate trends are insensitive to to τT Transient and increased with increasing staging equivalence ratio. The timescale of the transition, τ, is found to be sensitive to both τ Transient and the staging equivalence ratio. For a given τ Transient , the decay timescale decreased with increasing staging equivalence ratio. For 1, 16, and 58 ms transients, τ does not depend on τ Transient , though it does strongly depend on direction, where instability onset cases have longer and more variable τ than instability decay cases. The same dependence of τ on direction is seen for the 4,000 and 10,000 ms transients. However, unlike the short duration transients, τ does depend on τ Transient as would be expected. Phase space reconstruction shows the instability is a harmonic limit cycle with a single frequency. The instantaneous phase images shows the center region of the combustor goes out-of-phase first followed by the rest of the combustor. Finally, asymmetric fuel staging tests are conducted. It is found that non-axisymmetric staging can be as effective as axisymmetric staging, although small hardware variations between nozzles can affect the the minimum staging equivalence ratio that consistently suppresses the instability. These changes in the bifurcation equivalence ratio can make staging configurations appear less effective; however, both axisymmetric and non-axisymmetric staging configurations exhibit similar staged-stable p' RMS , damping rates, and instability transition times for equivalence ratios greater than the bifurcation equivalence ratio. Instantaneous phase images show similar instantaneous phase relationship structures in the staged nozzle (center or outer), suggesting that the instability suppression mechanism is similar in each case. This result is surprising given that the time-averaged flame shapes are very different between axisymmetric and non-axisymmetric staging configurations. The similar effectiveness of axisymmetric and non-axisymmetric staging in this geometry is attributed to the fact that the instability mode is a nominally axisymmetric plane wave. It is hypothesized that non-axisymmetric staging configurations will likely be more effective than axisymmetric staging configurations when the instability mode shape is asymmetric (such as a circumferential wave).

Culler, Wyatt↗

On the design of stable, consistent, and conservative high-order methods for multi-material hydrodynamics

Obtaining stable and high-order numerical solutions for multi-material hydrodynamics is an open challenge. Although slope limiters are widely used to maintain monotonicity near discontinuities, typical limiting procedures violate closure laws at the discrete level when applied to multi-material hydrodynamics equations. Due to this, the high-order expansions of quantities related by the closure laws are no longer consistent. The commonly observed symptom of this consistency-violation is that the numerical method fails to maintain constant pressure and velocity across material interfaces. This leads to sub-optimal convergence rates for smooth multi-material problems as well. Specialized limiting procedures that satisfy consistency while maintaining conservation need to be developed for such equations. A novel procedure that re-instates consistency into slope-limited high-order discretizations applied to the multi-material hydrodynamics equations is presented here. Using simple examples, it is demonstrated that the presented method satisfies closure laws at the discrete level, while maintaining conservative properties of the high-order method. Furthermore, this procedure involves a projection step which relies on the compact basis of the underlying spatial discretization, i.e. for discontinuous schemes (viz. DG and FV) the projection is local, and does not involve global matrix solves. Comparisons with conventional approaches emphasizes the necessity of the consistent closure-law preserving limiting approach, in order to maintain design order of accuracy for smooth multi-material problems.

36 MATERIALS SCIENCE↗

Polydopamine-treated three-dimensional carbon fiber-coated separator for achieving high-performance lithium metal batteries

The development of safe and high-performance lithium (Li) metal anodes has been a challenging issue that has not been addressed for decades. In this study, we have developed a thermally stable polydopamine-treated three-dimensional (3D) carbon fiber-coated separator (P3D-CFS) using an economical and environment-friendly process. P3D-CFS has a conductive coating layer that is used as a 3D hosting structure, which does not cause morphological changes in the Li metal anode. As a result, the unit cells (LiMn2O4/Li metal) employing P3D-CFS improve the cycle performance and rate capability compared to commercial polyethylene (PE) separators. P3D-CFS maintained 83.1% of the initial discharge capacity at the 400th cycle, whereas bare PE maintains only 74.3% of the initial discharge capacity after the 250th cycle (C/2?=?0.5?mA?cm-2). P3D-CFS maintains 42.8% of the initial discharge capacity at a 7C rate (7?mA?cm-2), whereas only 0.19% is maintained by bare PE under the same condition. Owing to the thermally stable properties of P3D-CFS, the open-circuit voltage of the unit cells (LiMn2O4/graphite) that employed P3D-CFS is maintained for over 60?min?at 140?°C, whereas the unit cells that employed bare PE show a sudden voltage drop after only 3?min.

Oh, Jeonghun↗

Iso-uncertainty control in an experimental fluoroscopy system

Purpose: X-ray fluoroscopy remains an important imaging modality in a number of image-guided procedures due to its real-time nature and excellent spatial detail. However, the radiation dose delivered raises concerns about its use particularly in lengthy treatment procedures (>0.5 h). The authors have previously presented an algorithm that employs feedback of geometric uncertainty to control dose while maintaining a desired targeting uncertainty during fluoroscopic tracking of fiducials. The method was tested using simulations of motion against controlled noise fields. In this paper, the authors embody the previously reported method in a physical prototype and present changes to the controller required to function in a practical setting. Methods: The metric for feedback used in this study is based on the trace of the covariance of the state of the system, tr(C). The state is defined here as the 2D location of a fiducial on a plane parallel to the detector. A relationship between this metric and the tube current is first developed empirically. This relationship is extended to create a manifold that incorporates a latent variable representing the estimated background attenuation. The manifold is then used within the controller to dynamically adjust the tube current and maintain a specified targeting uncertainty. To evaluate the performance of the proposed method, an acrylic sphere (1.6 mm in diameter) was tracked at tube currents ranging from 0.5 to 0.9 mA (0.033 s) at a fixed energy of 80 kVp. The images were acquired on a Varian Paxscan 4030A (2048 × 1536 pixels, ∼100 cm source-to-axis distance, ∼160 cm source-to-detector distance). The sphere was tracked using a particle filter under two background conditions: (1) uniform sheets of acrylic and (2) an acrylic wedge. The measured tr(C) was used in conjunction with a learned manifold to modulate the tube current in order to maintain a specified uncertainty as the sphere traversed regions of varying thickness corresponding to the acrylic sheets in the background. Results: With feedback engaged, the tracking error was found to correlate well with the specified targeting uncertainty. Tracking of the fiducial was found to be robust to changes in the attenuation presented by the varying background conditions. For a desired uncertainty of 5.0 mm, comparison of the feedback framework with a comparable system employing fixed exposure demonstrated dose savings of 29%. Conclusions: This work presents a relation between a state descriptor, tr(C), the x-ray tube current used, and an estimate of the background attenuation. This relation is leveraged to modulate the tube current in order to maintain a desired geometric uncertainty during fluoroscopy. The authors’ work demonstrates the use of the method in a real x-ray fluoroscopy system with physical motion against varying backgrounds. The method offers potential savings in imaging dose to patients and staff while maintaining tracking uncertainty during fluoroscopy-guided treatment procedures.

60 APPLIED LIFE SCIENCES↗

Operation and Maintenance of the National Radiobiology Archives

The National Radiobiology Archives (NRA) are an archival program, started in 1989, to collect, organize and maintain data, laboratory notebooks, and animal tissue specimens from government (Department of Energy and its predecessor agencies) sponsored radiobiology life-span animal studies. These unique records, histopathology slides and paraffin embedded tissue blocks are maintained in a central facility and are available for further research study. The materials include electronic and paper records for each of more than 6,000 life-span-observations on dogs as well as details of major studies involving nearly 30,000 mice. Although these studies were performed over many years and at different laboratories with differing data management systems, the NRA has translated them into a standardized set of relational database tables. These can be distributed to interested individuals on written request. Specific Aims are: (1) To Maintain the Archive of Written Records from the Animal Experiments - The USTUR continued to maintain the NRA archives which consist of approximately 175 storage boxes containing laboratory notebooks, animal exposure records, animal pathologic records, and radiographs. These were stored in a 6,000 square foot leased facility in Richland, WA. Additionally, through a collaboration with Pacific Northwest National Laboratory's (PNNL) Low Dose Program, many of these records were scanned into digital files. These totaled 34 GB of data, which are saved in 2,407 separate PDF files that are organized by box number and animal identification number. (2) To Maintain the Archive of Animal Tissues at Washington State University - The USTUR continued to house the NRA dog tissue collection in the leased facility. The NRA tissue collection consisted of pathology slides and tissue blocks. Approximately 25% of the laboratory facility was dedicated to the storage of the NRA materials. (3) To Organize the Datasets of These Animals in the Context of Other Datasets so That They Can be Used by the Scientific Community at Large - As was reported in the FY2009 NRA progress report, Dr. Chuck Watson (NRA Database Consultant) completed his service as the US representative on the European Radiobiological Archives (ERA) Advisory Board during FY2009. Unfortunately, due to the lack of financial support during FY2010, the NRA was not able to make further contributions to the ERA's efforts.

59 BASIC BIOLOGICAL SCIENCES↗

Survey of U.S. Ancillary Services Markets

In addition to providing energy to end-consumers, power system operators are also responsible for ensuring system reliability. To this end, power markets maintain an array of ancillary services to ensure that it is always possible to balance the supply and demand for energy in real-time. A subset of these ancillary services are commonly procured through market-based mechanisms: namely, Regulation, Spinning, and Non-spinning Reserves. Regulation Reserves are maintained to respond to supply/demand imbalances over short time frames, typically on the order of several seconds to one minute. Resources that provide Regulation Reserves adjust their generation or load levels in response to automatic generation control (AGC) signals provided by the system operator. Contingency reserves are maintained to provide additional generation capacity in the event that load increases substantially or supply side resources reduce their output or are taken offline. The reserves are typically segmented into two categories, 1) Spinning or Synchronized Reserves that are provided by generation units that are actively generating and have the ability to increase or decrease their output, 2) Non-spinning or Non-synchronized Reserves that are provided by generation resources that are not actively generating, but are able to start up and provide generation within a specified timeframe. Contingency reserves typically have response times on the order of ten to 30 minutes and can also be provided by demand-side resources that are capable of reducing their load. There are seven distinct power markets in the United States, each operated by a Regional Transmission Operator (RTO) or Independent System Operator (ISO) that operates the transmission system in its territory, operates markets for energy and ancillary services, and maintains system reliability. Each power market offers its own set of ancillary services, and precise definitions, requirements, and market mechanisms differ between markets. Despite the differences between markets, both in terms of services offered and system requirements, some broad trends generally apply. Regulation Reserves typically have the highest market prices, followed by Spinning Reserves and Non-spinning Reserves. Prices for Regulation Reserves have been the highest in the PJM market, since it opened in October 2012. This is partially because PJM experienced large price spikes during the period of extreme weather conditions in early 2014. ERCOT has traditionally had the highest prices for Spinning Reserves (called Responsive Reserves in ERCOT), including several periods of sustained high prices between 2010 and 2012. This can be explained in part by the relatively high penetration of variable wind resources and a similarly high requirement relative to peak load. ERCOT has also traditionally had the highest price for Non-spinning Reserves, followed by the NYISO East region. Both have experienced several periods of prolonged high prices since their inception, an occurrence that has not been regularly seen in other markets. In ISO-NE and PJM for example, the market clearing price for Non-spinning Reserves is typically $0/MWh more than 95% of the time. Market volume (in terms of the average amount of capacity of each service that is provided to a system) typically follows the reverse order of prices, as systems maintain the most Non-spinning Reserves capacity followed by Spinning Reserves and Regulation Reserves. PJM generally has the largest market for Regulation Reserves both in terms of capacity. The size of most Regulation Reserves markets in terms of capacity stay relatively constant year-to-year, as this is dictated largely by system requirements. PJM also generally has the largest Spinning Reserves market in terms of capacity. SPP, MISO, ISO-NE and SPP (beginning in 2014) all have Spinning Reserve markets with similar average capacity levels. When combined, the markets for Non-spinning and Operating reserves in ISO-NE have a comparable capacity to the market for Primary Reserves 1 in PJM. SPP, MISO, and CAISO all have smaller markets for their respective Non-spinning Reserves products that are roughly the same size as each other in terms of capacity.

29 ENERGY PLANNING, POLICY, AND ECONOMY↗

Integrated Logistics Support Analysis of the International Space Station Alpha: An Overview of the Maintenance Time Dependent Parameter Prediction Methods Enhancement

The objective of this publication is to introduce the enhancement methods for the overall reliability and maintainability methods of assessment on the International Space Station. It is essential that the process to predict the values of the maintenance time dependent variable parameters such as mean time between failure (MTBF) over time do not in themselves generate uncontrolled deviation in the results of the ILS analysis such as life cycle costs, spares calculation, etc. Furthermore, the very acute problems of micrometeorite, Cosmic rays, flares, atomic oxygen, ionization effects, orbital plumes and all the other factors that differentiate maintainable space operations from non-maintainable space operations and/or ground operations must be accounted for. Therefore, these parameters need be subjected to a special and complex process. Since reliability and maintainability strongly depend on the operating conditions that are encountered during the entire life of the International Space Station, it is important that such conditions are accurately identified at the beginning of the logistics support requirements process. Environmental conditions which exert a strong influence on International Space Station will be discussed in this report. Concurrent (combined) space environments may be more detrimental to the reliability and maintainability of the International Space Station than the effects of a single environment. In characterizing the logistics support requirements process, the developed design/test criteria must consider both the single and/or combined environments in anticipation of providing hardware capability to withstand the hazards of the International Space Station profile. The effects of the combined environments (typical) in a matrix relationship on the International Space Station will be shown. The combinations of the environments where the total effect is more damaging than the cumulative effects of the environments acting singly, may include a combination such as temperature, humidity, altitude, shock, and vibration while an item is being transported. The item's acceptance to its end-of-life sequence must be examined for these effects.

Sepehry-Fard, F.↗

Growth and maintenance of an embryogenic cell culture of daylily (Hemerocallis) on hormone-free medium

Callus cultures of the diploid daylily (Hemerocallis) clone Autumn Blaze' were initiated and maintained in hormone-containing nutrient medium. At various times (from 6 weeks to 1 year) after being initiated, hormone-derived cultures were evaluated for their ability to be maintained and to multiply on hormone-free medium at low pH (between pH 4 and 4.5). Cultures had to be exposed to hormone-containing medium for at least 12 weeks before they could be maintained on hormone-free medium at low pH. The transition to maintainability on low pH hormone-free medium included the production of many aberrant embryonal forms ( neomorphs'). However, all hormone-derived cultures tested consisted entirely of preglobular stage proembryos (PGSPs) after 12-24 weeks on low pH hormone-free medium. PGSP cultures have been maintained and multiplied as such for over 1 year on low pH hormone-free medium. PGSPs continue their development into various somatic embryo stages when cultured on hormone-free medium buffered at pH 5.8. The production of well-formed somatic embryos was greatly enhanced when PGSPs were plated on activated charcoal impregnated filter papers that were placed on top of the agar surface. The gross morphology and histology of the PGSPs and stages of somatic embryo development are presented. The work shows that the ability of hormone-free medium at low pH to permit PGSP multiplication without development into later stages of embryo development is not restricted to carrot.

Non-NASA Center↗

An Interoperability Concept for Detect and Avoid and Collision Avoidance Systems: Results from a Human-In-The-Loop Simulation

The integration of Unmanned Aircraft Systems (UAS) into the National Airspace System (NAS) poses a variety of technical challenges to UAS developers and aviation regulators. In response to growing demand for access to civil airspace in the United States, the Federal Aviation Administration (FAA) has produced a roadmap identifying key areas requiring further research and development. One such technical challenge is the development of a "detect and avoid" system (DAA) capable of providing a means of compliance with the "see and avoid" requirement in manned aviation. The purpose of the DAA system is to support the pilot, situated at a ground control station (GCS), in maintaining "DAA well clear" of nearby aircraft through the use of GCS displays and alerts. In addition to its primary function of aiding the pilot in maintaining DAA well clear, the DAA system must also safely interoperate with existing NAS systems and operations, such as the airspace management procedures of air traffic controllers (ATC) and Collision Avoidance (CA) systems currently in use by manned aircraft, namely the Traffic Alert and Collision Avoidance System (TCAS II). It is anticipated that many UAS architectures will integrate both a DAA system and a TCAS II. It is therefore necessary to explicitly study the integration of DAA and TCAS II alerting structures and maneuver guidance formats to ensure that pilots understand the appropriate type and urgency of their response to the various alerts. This paper presents a concept of interoperability for the two systems. The concept was developed with the goal of avoiding any negative impact on the performance level of TCAS II while retaining a DAA system that still effectively enables pilots to maintain DAA well clear. The interoperability concept described in the paper focuses primarily on facilitating the transition from a late-stage DAA encounter (where a loss of DAA well clear is imminent) to a TCAS II Corrective Resolution Advisory (RA), which requires pilot compliance within five seconds of its issuance. The interoperability concept was presented to 10 participants (6 active UAS pilots and 4 active commercial pilots) in a medium-fidelity, human-in-the-loop simulation designed to stress different aspects of the DAA and TCAS II systems. Pilots' ability to maintain separation, their rate of compliance and response times using the interoperability concept are reported. Results indicated that pilots exhibited comprehension of, and appropriate prioritization within, the DAA-TCAS II combined alert structure. Pilots demonstrated a high rate of compliance with TCAS II RAs and were also seen to respond to corrective RAs within the five second requirement established for manned aircraft. The DAA system presented under test was also shown to be effective in supporting pilots' ability to maintain DAA well clear in the overwhelming majority of cases in which pilots had sufficient time to respond.

Rorie, R. Conrad↗

Risk of Impaired Performance Due to Reduced Muscle Mass, Strength &, Endurance (Short Title: Muscle) and Risk of Reduced Physical Performance Capabilities Due to Reduced Aerobic Capacity (Short Title: Aerobic)

This report reviews the scientific literature regarding the human system risks to the microgravity environment of space flight in relation to human performance. The primary human performance-related risks involve deconditioning of the cardiovascular and skeletal muscles systems due to prolonged exposure to the reduced gravitational input. The chronological history of U.S. space flight is reviewed as a starting point to inform and understand the gaps in the knowledge to these risks. Maintenance of physical performance capabilities involves understanding the health of many organ systems (peripheral [vascular, heart, blood volume, skeletal muscle] and central [brain]) that ultimately contribute to the submaximal and maximal capacity of the aerobic (VO2peak), skeletal muscle (strength and endurance) systems. Maintaining astronaut VO2peak, muscle mass, strength, and endurance before, during, and after space flight is a significant priority to NASA for the current International Space Station (ISS) era, as well as for future exploration missions. A growing research database from both space flight and ground-based analog studies finds that the cardiorespiratory system is compromised and skeletal muscles (predominantly postural muscles of the lower limbs) undergo atrophy. These structural and metabolic responses to living in microgravity conditions contribute to physiological deconditioning during space flight that potentially increase the risks to astronauts returning to surface operations (i.e., Moon, Mars, or Earth). The time course changes from short to long-duration space flight and the relationships between in-flight performance deconditioning levels are not well characterized. Moreover, there are large interindividual variabilities that may be dependent on genetics, age, sex, preflight fitness levels, and individual exercise prescriptions that need further careful evaluations. Efforts should be made to understand the current status of preflight, in-flight, and postflight exercise performance capability and to define the operational goals and target areas for protection with the in-flight exercise program. There is a bi-directional relationship between exercise prescription and hardware countermeasures that need further understanding in-flight. For example, hardware with limited capabilities/modalities may be counterbalanced by changes in exercise prescription (i.e., frequency, time, intensity, volume) for providing effective responses to maintain fitness. Importantly, the minimal requirements for exercise prescription on ISS hardware may not translate to lower capability hardware on exploration missions. Due to limited volume on exploration vehicles, future Artemis missions to the Lunar surface will not have similar exercise hardware capabilities as ISS. This may alter the effectiveness of hardware to provide adequate physiological stress on bodily systems allowing for adaptations to maintain aerobic capacity, strength, and bone density. Thus, it will be important to understand the exercise responses of current ISS countermeasures to develop individualized exercise prescriptions that minimize aerobic and muscular risks, accounting for the large variability of responses among crewmembers. Newer exploration exercise hardware is currently being evaluated that is more compact (i.e., E4D and Orion Flywheel) and will require careful evaluation of the hardware on the stressor (i.e., metabolic rate, oxygen uptake, and heart rate work relationships, and force plate load profiles) needed the human body to protect and maintain crew health and performance. Moreover, exercise responses on the hardware need careful evaluation on the chronic adaptations. Lastly, in-flight evaluation of hardware exercise response may differ in 0-g or partial-g compared to 1-g. Therefore, it cannot be assumed that the stress on the body will be the same in each environment. Understanding this has a direct impact on exercise prescriptions. This document provides an overview of key scientific investigations that have been conducted before, during, and after human space flight missions, as well as from human ground-based analog studies that contribute to the evidence base on changes in aerobic capacity and muscle mass, strength, and endurance. Additional data from rodent and nonhuman primate experiments of skeletal muscle unloading completed during space flight or ground-based flight-simulations provide supportive information about this risk topic. Most importantly, a recent, large dataset from long-duration ISS crew has been added to give improved insight into the variability of exercise response of crew, demonstrating that a large portion of the crew population return to Earth with greater than 10-20% loss of aerobic capacity and muscle strength and endurance. Data from human space flight and ground-based studies are narrowing in on the required exercise paradigms but thus far still provide an incomplete answer to an effective approach for maintaining skeletal muscle function and aerobic fitness of all human space travelers. Finally, the relationship of this risk topic to various space flight operational scenarios is examined and discussed.

Eric Rivas↗