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At least 595 records · Page 33

Modeling Space Radiation with Radiomimetic Agent Bleomycin

Space radiation consists of proton and helium from solar particle events (SPE) and high energy heavy ions from galactic cosmic ray (GCR). This mixture of radiation with particles at different energy levels has different effects on biological systems. Currently, majority studies of radiation effects on human were based on single-source radiation due to the limitation of available method to model effects of space radiation on living organisms. While NASA Space Radiation Laboratory is working on advanced switches to make it possible to have a mixed field radiation with particles of different energies, the radiation source will be limited. Development of an easily available experimental model for studying effects of mixed field radiation could greatly speed up our progress in our understanding the molecular mechanisms of damage and responses from exposure to space radiation, and facilitate the discovery of protection and countermeasures against space radiation, which is critical for the mission to Mars. Bleomycin, a radiomimetic agent, has been widely used to study radiation induced DNA damage and cellular responses. Previously, bleomycin was often compared to low low Linear Energy Transfer (LET) gamma radiation without defined characteristics. Our recent work demonstrated that bleomycin could induce complex clustered DNA damage in human fibroblasts that is similar to DNA damage induced by high LET radiation. These type of DNA damage is difficult to repair and can be visualized by gamma-H2Ax staining weeks after the initial insult. The survival ratio between early and late plating of human fibroblasts after bleomycin treatment is between low LET and high LET radiation. Our results suggest that bleomycin induces DNA damage and other cellular stresses resembling those resulted from mixed field radiation with both low and high LET particles. We hypothesize that bleomycin could be used to mimic space radiation in biological systems. Potential advantages and limitations of using bleomycin to treat biological specimen as an easily available model to study effects of space radiation on biological systems and to develop countermeasures for space radiation associated risks will be discussed.

Lu, Tao↗

Velocity Measurement in a Dual-Mode Supersonic Combustor using Particle Image Velocimetry

Temporally and spatially-resolved, two-component measurements of velocity in a supersonic hydrogen-air combustor are reported. The combustor had a single unswept ramp fuel injector and operated with an inlet Mach number of 2 and a flow total temperature approaching 1200 K. The experiment simulated the mixing and combustion processes of a dual-mode scramjet operating at a flight Mach number near 5. The velocity measurements were obtained by seeding the fuel with alumina particles and performing Particle Image Velocimetry on the mixing and combustion wake of the ramp injector. To assess the effects of combustion on the fuel air-mixing process, the distribution of time-averaged velocity and relative turbulence intensity was determined for the cases of fuel-air mixing and fuel-air reacting. Relative to the mixing case, the near field core velocity of the reacting fuel jet had a slower streamwise decay. In the far field, downstream of 4 to 6 ramp heights from the ramp base, the heat release of combustion resulted in decreased flow velocity and increased turbulence levels. The reacting measurements were also compared with a computational fluid dynamics solution of the flow field. Numerically predicted velocity magnitudes were higher than that measured and the jet penetration was lower.

Goyne, C. P.↗

Grain motions in the solar nebula

Isotopic analyses of meteorites suggest the possibility that some interaction between supernova ejecta and grains occurred in the solar nebula. In particular, the dynamics of grain motions in the solar nebula can explain the observed mixing of nucleosynthetic components. The effect of a shock wave on the motions of grains is examined. On the basis of calculations, it is estimated that if grains carried the isotopic anomalies investigated by Lee, Papanastassoiu, and Wasserburg (1978), then those grains could be no bigger than 0.0002 cm in size. A scenario is suggested in which the sluggishness of grains provides a natural way to concentrate and mix the nucleosynthetic components carried by grains in the ejecta and in the solar nebula.

Margolis, S. H.↗

Validation of the aerosol optical property products derived by the GRASP/Component approach from multi-angular polarimetric observations

The multi-angle polarimetric satellite observations are helpful for improving the retrievals of aerosol parameters. However, practical applications of polarization technology are still limited because of complexity of measurement and interpretation of polarimetric observations. In this study, we analyze the performance of a new component approach developed in the frame of the Generalized Retrieval of Atmosphere and Surface Properties (GRASP) algorithm. In addition to aerosol optical properties including particle size distribution, non-sphericity and index of refraction that are commonly derived from multi-angle radiance and polarization measurements, the GRASP/Component approach also provides some information about aerosol composition. Specifically, in this approach aerosol is modeled as an internal mixture of several components with distinctly different chemical compositions and known refractive indices. The approach is intended not only to provide additional insight on aerosol composition but also to improve retrieval of basic aerosol optical properties. This study presents comprehensive validation and evaluation of Aerosol Optical Depth (AOD), Ångstrom exponent (AE), fine mode AOD (AODF), coarse mode AOD (AODC), and single scattering albedo (SSA) as retrieved by the GRASP/Component approach. The GRASP/Component products include aerosol retrievals using two different aerosol component mixing rules, i.e., Maxwell-Garnett (MG) effective medium approximation and a simple Volume- Weighted averaging (VW). The differences between the results obtained using these two assumptions are also discussed. The obtained results show that the aerosol optical property products of GRASP/Component approach have good agreement with the ground-based AERONET measurements, which is comparable to other PARASOL/ GRASP approaches. Specifically, the AOD retrieved by GRASP/Component approach show high correlation and nearly no bias both over land and ocean, as compared with AERONET. The more detailed aerosol properties such as AE, AODF, AODC and SSA also show one of the best comparisons with AERONET. These improvements can probably be attributed to the use of the additional physical constraints on spectral dependence of the complex refractive index and the reduction of total number of aerosol parameters directly retrieved in the GRASP/Component approach. In addition, the choice of mixing rules had no significant effect on optical retrievals. With the exception of SSA, the results obtained based on the MG mixing rule were found to be slightly better over those obtained using VW mixing rule, especially for bias.

Brent N Holben↗

Normal injection of helium from swept struts into ducted supersonic flow

Recent design studies have shown that airframe-integrated scramjets should include instream mounted, swept-back strut fuel injectors to obtain short combustors. Because there was no data in the literature on mixing characteristics of swept strut fuel injectors, the present investigation was undertaken to provide such data. This investigation was made with two swept struts in a closed duct at Mach number of 4.4 and nominal jet-to-air mass flow ratio of 0.029 with helium used to simulate hydrogen fuel. The data is compared with flat plate mounted normal injector data to obtain the effect of swept struts on mixing. Three injector patterns were evaluated representing the range of hole spacing and jet-to-freestream dynamic pressure ratio of interest. Measured helium concentration, pitot pressure, and static pressure in the downstream mixing region are used to generate contour plots necessary to define the mixing region flow field and the mixing parameters.

Mcclinton, C. R.↗

Remote Sensing of Aerosol Water Fraction, Dry Size Distribution and Soluble Fraction Using Multi-Angle, Multi-Spectral Polarimetry

A framework to infer volume water fraction, soluble fraction and dry size distributions of fine-mode aerosol from multi-angle, multi-spectral polarimetry retrievals of column-averaged ambient aerosol properties is presented. The method is applied to observations of the Research Scanning Polarimeter (RSP) obtained during two NASA aircraft campaigns, namely the Aerosol Cloud meTeorology Interactions oVer the western ATlantic Experiment (ACTIVATE) and the Cloud, Aerosol, and Monsoon Processes Philippines Experiment (CAMP2Ex). All aerosol retrievals are statistically evaluated using in situ data. Volume water fraction is inferred from the retrieved ambient real part of the refractive index, assuming a dry refractive index of 1.54 and by applying a volume mixing rule to obtain the effective ambient refractive index. The uncertainties in inferred volume water fraction resulting from this simplified model are discussed and estimated to be lower than 0.2 and decreasing with increasing volume water fraction. The daily mean retrieved volume water fractions correlate well with the in situ values with a mean absolute difference of 0.09. Polarimeter-retrieved ambient effective radius for daily data is shown to increase as a function of volume water fraction as expected. Furthermore, the effective variance of the size distributions also increases with increasing effective radius, which we show is consistent with an external mixture of soluble and insoluble aerosol. The relative variations of effective radius and variance over an observation period are then used to estimate the soluble fraction of the aerosol. Daily results of soluble fraction correlate well with in situ-observed sulfate mass fraction with a correlation coefficient of 0.79. Subsequently, inferred water and soluble fractions are used to derive dry fine-mode size distributions from their ambient counterparts. While dry effective radii obtained in situ and from RSP show similar ranges, in situ values are generally substantially smaller during the ACTIVATE deployments, which may be due to biases in RSP retrievals or in the in situ observations, or both. Both RSP and in situ observations indicate the dominance of aerosol with low hygroscopicity during the ACTIVATE and CAMP2Ex campaigns. Furthermore, RSP indicates a high degree of external mixing of particles with low and high hygroscopicity. These retrievals of fine-mode water volume fraction and soluble fraction may be used for the evaluation of water uptake in atmospheric models. Furthermore, the framework allows us to estimate the variation in the concentration of fine-mode aerosol larger than a specific dry radius limit, which can be used as a proxy for the variation in cloud condensation nucleus concentrations. This framework may be applied to multi-angle, multi-spectral satellite data expected to be available in the near future.

Amount of water in particulate matter↗

Remote Sensing of Aerosol Water Fraction, Dry Size Distribution and Soluble Fraction Using Multi-Angle, Multi-Spectral Polarimetry

A framework to infer volume water fraction, soluble fraction and dry size distributions of fine mode aerosol from multi-angle, multi-spectral polarimetry retrievals of column-averaged ambient aerosol properties is presented. The method is applied to observations of the Research Scanning Polarimeter (RSP) obtained during two NASA aircraft campaigns, namely the Aerosol Cloud meTeorology Interactions oVer the western ATlantic Experiment (ACTIVATE) and the Cloud, Aerosol, and Monsoon Processes-Philippines Experiment (CAMP2Ex). All aerosol retrievals are statistically evaluated using in situ data. Volume water fraction is inferred from the retrieved ambient real part of the refractive index, assuming a dry refractive index of 1.54 and by applying a volume mixing rule to obtain the effective ambient refractive index. The uncertainties in inferred volume water fraction resulting from this simplified model are discussed and estimated to be lower than 0.2 and decreasing with increasing volume water fraction. The daily mean retrieved volume water fractions correlate well with the in situ values with a mean absolute difference of 0.09. Polarimeter-retrieved ambient effective radius for daily data is shown to increase as a function of volume water fraction as expected. Furthermore, the effective variance of the size distributions also increases with increasing effective radius, which we show is consistent with an external mixture of soluble and insoluble aerosol. The relative variations of effective radius and variance over an observation period are then used to estimate the soluble fraction of the aerosol. Daily results of soluble fraction correlate well with in situ observed sulfate mass fraction with a correlation coefficient of 0.79. Subsequently, inferred water and soluble fractions are used to derive dry fine-mode size distributions from their ambient counterparts. While dry effective radii obtained in situ and from RSP show similar ranges, in situ values are generally substantially smaller during the ACTIVATE deployments, which may be due to biases in RSP retrievals or in the in situ observations, or both. Both RSP and in situ observations indicate the dominance of aerosol with low hygroscopicity during the ACTIVATE and CAMP2Ex campaigns. Furthermore, RSP indicates a high degree of external mixing of particles with low and high hygroscopicity. These retrievals of fine mode water volume fraction and soluble fraction may be used for the evaluation of water uptake in atmospheric models. Furthermore, the framework allows to estimate the variation in the concentration of fine-mode aerosol larger than a specific dry radius limit, which can be used as a proxy for the variation in cloud condensation nucleus concentrations. This framework may be applied to multi-angle, multi-spectral satellite data expected to be available in the near future.

Bastiaan Van Diedenhoven↗

An Assessment of Stratospheric Water Vapor Trends and Variations Above the Boulder Region

This study analyzes time series of stratospheric water vapor (SWV) data at 30 hPa, based on frost-point hygrometer (FPH) measurements at Boulder, CO (40°N, 255°E), and on sets of HALOE scans above that region for 1993 through 2005; their differing trends agree with previously published findings. Yet, there is an apparent switch over in 2002 from positive to negative trends in the HALOE time series, and that change follows the episodic decrease of tropical, lower stratospheric SWV in early 2001. The HALOE data points only resolve medium to large scale spatial variations, as they are based on an average of four or more limb scans within a latitude/longitude sector near Boulder. The FPH time series do not indicate a similar change of trend in 2002, although its time series points have variations about the mean that are twice as large as those from HALOE. The FPH soundings are sensitive to variations from all spatial scales, however, including the effects of a local vertical mixing of the air due to gravity waves. The vertical gradient SWV mixing ratio with altitude is positive at 30 hPa. There is also a positive trend in methane and its conversion to water vapor during this time that may explain a slightly larger SWV trend from the local FPH data than from the HALOE data. The Nimbus 7 LIMS experiment provides daily SWV plots at medium to large scales during the dynamically active, winter and springtime periods, for assessing the effects of meridional transport of SWV from its source regions. There is transport of high SWV from polar regions and of lower SWV from the subtropics at those times. SWV variations and trends from both the FPH and HALOE time series are reasonable and in accord with the spatial scales that they observed.

Ellis Remsberg↗

Development of a two-stream mixing layer from tripped and untripped boundary layers

The effects of the state of the initial boundary layers on the development of a two-stream, plane mixing layer, with a velocity ratio of 0.6 are experimentally investigated. Spanwise-average profiles are compared for the first time. The results indicate that both the near and far-field growth rates for the untripped case are significantly higher than the tripped case. The maximum Reynolds stresses and higher-order products for the two cases behave very differently in the near-field, but asymptote to approximately the same constant levels far downstream. The mean velocity and turbulence profiles in this region also collapse adequately for the two cases when plotted in similarity coordinates. The distance required to achieve self-similarity is distinctly shorter for the tripped case, in contrast to previous observations. The higher growth rate for the untripped case is attributed to the presence of streamwise vortices which result in additional entrainment by the mixing layer.

Bell, James H.↗

Atomization characteristics of swirl injector sprays

Stable combustion within rocket engines is a continuing concern for designers of rocket engine systems. The swirl-coaxial injector has demonstrated effectiveness in achieving atomization and mixing, and therefore stable combustion. Swirl-coaxial injector technology is being deployed in the American RL1OA rocket design and Russian engine systems already make wide spread use of this technology. The present requirement for swirl injector research is derived from NASA's current Reusable Launch Vehicle (RLV) technology program. This report describes some of the background and literature on this topic including drop size measurements, comparison with theoretical predictions, the effect of surface tension on the atomization process, and surface wave characteristics of liquid film at the exit of the injector.

Feikema, Douglas A.↗

Radiative Forcing by Well-Mixed Greenhouse Gases: Estimates from Climate Models in the Intergovernmental Panel on Climate Change (IPCC) Fourth Assessment Report (AR4)

The radiative effects from increased concentrations of well-mixed greenhouse gases (WMGHGs) represent the most significant and best understood anthropogenic forcing of the climate system. The most comprehensive tools for simulating past and future climates influenced by WMGHGs are fully coupled atmosphere-ocean general circulation models (AOGCMs). Because of the importance of WMGHGs as forcing agents it is essential that AOGCMs compute the radiative forcing by these gases as accurately as possible. We present the results of a radiative transfer model intercomparison between the forcings computed by the radiative parameterizations of AOGCMs and by benchmark line-by-line (LBL) codes. The comparison is focused on forcing by CO2, CH4, N2O, CFC-11, CFC-12, and the increased H2O expected in warmer climates. The models included in the intercomparison include several LBL codes and most of the global models submitted to the Intergovernmental Panel on Climate Change (IPCC) Fourth Assessment Report (AR4). In general, the LBL models are in excellent agreement with each other. However, in many cases, there are substantial discrepancies among the AOGCMs and between the AOGCMs and LBL codes. In some cases this is because the AOGCMs neglect particular absorbers, in particular the near-infrared effects of CH4 and N2O, while in others it is due to the methods for modeling the radiative processes. The biases in the AOGCM forcings are generally largest at the surface level. We quantify these differences and discuss the implications for interpreting variations in forcing and response across the multimodel ensemble of AOGCM simulations assembled for the IPCC AR4.

Collins, W. D.↗

Effects of sweep on controls

An analysis of the principal results of recent control-surface research pertinent to transonic flight has been made. An indication of the nature of the changes in control-surface characteristics above the critical speed of the wing and a preliminary design procedure for estimating the effectiveness of flap-type controls on swept wings are presented.

CONTROLS, FLAP TYPE - COMPLETE WINGS↗

Multiple jet study

Test data is presented which allows determination of jet penetration and mixing of multiple cold air jets into a ducted subsonic heated mainstream flow. Jet-to-mainstream momentum flux ratios ranged from 6 to 60. Temperature profile data is presented at various duct locations up to 24 orifice diameters downstream of the plane of jet injection. Except for two configurations, all geometries investigated had a single row of constant diameter orifices located transverse to the main flow direction. Orifice size and spacing between orifices were varied. Both of these were found to have a significant effect on jet penetration and mixing. The best mixing of the hot and cold streams was achieved with duct height.

Walker, R. E.↗

Analysis and testing of two-dimensional vented Coanda ejectors with asymmetric variable area mixing sections

The analysis of asymmetric, curved (Coanda) ejector flow has been completed using a finite difference technique and a quasi-orthogonal streamline coordinate system. The boundary layer type jet mixing analysis accounts for the effect of streamline curvature in pressure gradients normal to the streamlines and on eddy viscosities. The analysis assured perfect gases, free of pressure discontinuities and flow separation and treated three compound flows of supersonic and subsonic streams. Flow parameters and ejector performance were measured in a vented Coanda flow geometry for the verification of the computer analysis. A primary converging nozzle with a discharge geometry of 0.003175 m x 0.2032 m was supplied with 0.283 cu m/sec of air at about 241.3 KPa absolute stagnation pressure and 82 C stagnation temperature. One mixing section geometry was used with a 0.127 m constant radius Coanda surface. Eight tests were run at spacing between the Coanda surface and primary nozzle 0.01915 m and 0.318 m and at three angles of Coanda turning: 22.5 deg, 45.0 deg, and 75.0 deg. The wall static pressures, the loci of maximum stagnation pressures, and the stagnation pressure profiles agree well between analytical and experimental results.

Maroti, L. A.↗

Understanding the Atmosphere of 51 Eri b: Do Photochemical Hazes Cloud the Planets Spectrum?

The first young giant planet to be discovered by the Gemini Planet Imager was the (is) approximately 2MJ planet 51 Eri b. This approximately 20 Myr old young Jupiter is the first directly imaged planet to show unmistakable methane in H band. To constrain the planet's mass, atmospheric temperature, and composition, the GPI J and H band spectra as well as some limited photometric points were compared to the predictions of substellar atmosphere models. The best fitting models reported in the discovery paper (Macintosh et al. 2015) relied upon a combination of clear and cloudy atmospheric columns to reproduce the data. However for an object as cool as 700 K, the origin of the cloud coverage is somewhat puzzling, as the global silicate and iron clouds would be expected to have sunk well below the photosphere by this effective temperature. While strong vertical mixing in these low gravity atmospheres remains a plausible explanation, we have explored whether atmospheric photochemistry, driven by the UV flux from the primary star, may yield hazes that also influence the observed spectrum of the planet. To explore this possibility we have modeled the atmospheric photochemistry of 51 Eri b using two state-of-the-art photochemical models, both capable of predicting yields of complex hydrocarbons under various atmospheric conditions. In our presentation we will summarize the modeling approach employed to characterize 51 Eri b, explaining constraints on the planet's effective temperature, gravity, and atmospheric composition and also present results of our studies of atmospheric photochemistry. We will discuss whether photochemical hazes could indeed be responsible for the particulate opacity that apparently sculpts the spectrum of the planet.

GPI - Gemini Planet Imager↗

Kinetic Temperature and Electron Density Measurement in an Inductively Coupled Plasma Torch using Degenerate Four-Wave Mixing

Laser wave mixing is presented as an effective technique for spatially resolved kinetic temperature measurements in an atmospheric-pressure radio-frequency inductively-coupled plasma. Measurements are performed in a 1 kW, 27 MHz RF plasma using a continuous-wave, tunable 811.5-nm diode laser to excite the 4s(sup 3)P2 approaches 4p(sup 3)D3 argon transition. Kinetic temperature measurements are made at five radial steps from the center of the torch and at four different torch heights. The kinetic temperature is determined by measuring simultaneously the line shape of the sub-Doppler backward phase-conjugate degenerate four-wave mixing and the Doppler-broadened forward-scattering degenerate four-wave mixing. The temperature measurements result in a range of 3,500 to 14,000 K+/-150 K. Electron densities measured range from 6.1 (+/-0.3) x 10(exp 15)/cu cm to 10.1 (+/-0.3) x 10(exp 15)/cu cm. The experimental spectra are analyzed using a perturbative treatment of the backward phase-conjugate and forward-geometry wave-mixing theory. Stark width is determined from the collisional broadening measured in the phase-conjugate geometry. Electron density measurements are made based on the Stark width. The kinetic temperature of the plasma was found to be more than halved by adding deionized water through the nebulizer.

Schafer, Julia↗