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At least 595 records · Page 33

Harnessing photoenzymatic reactions for unnatural biosynthesis in microorganisms

Photobiocatalysis provides a powerful strategy for integrating light and biological catalysts to drive abiological transformations. However, its scalability is hindered by high enzyme loading, reliance on costly cofactors and instability under radical-generating conditions. Here we report the integration of light-driven enzymatic reactions into the cellular metabolism of Escherichia coli, bridging flavin-based photobiocatalysis with biosynthesis. Using synthetic biology strategies, we engineered microbial cells to continuously produce olefin substrates and ene-reductase while regenerating cofactors directly from glucose. By externally supplying radical precursors or introducing synthetic pathways for their in situ production, we enabled fermentation-based microbial photobiosynthesis, achieving high titres and demonstrating feasibility for scale-up in a bioreactor. This approach extends photobiocatalysis from in vitro applications to in vivo semi- and complete biosynthesis, revealing its full potential for integrating light-driven reactions into cellular metabolism.

Biocatalysis↗

Volcano infrasound: progress and future directions

Over the past two decades (2000–2020), volcano infrasound (acoustic waves with frequencies less than 20 Hz propagating in the atmosphere) has evolved from an area of academic research to a useful monitoring tool. As a result, infrasound is routinely used by volcano observatories around the world to detect, locate, and characterize volcanic activity. It is particularly useful in confirming subaerial activity and monitoring remote eruptions, and it has shown promise in forecasting paroxysmal activity at open-vent systems. Fundamental research on volcano infrasound is providing substantial new insights on eruption dynamics and volcanic processes and will continue to do so over the next decade. The increased availability of infrasound sensors will expand observations of varied eruption styles, and the associated increase in data volume will make machine learning workflows more feasible. More sophisticated modeling will be applied to examine infrasound source and propagation effects from local to global distances, leading to improved infrasound-derived estimates of eruption properties. Future work will use infrasound to detect, locate, and characterize moving flows, such as pyroclastic density currents, lahars, rockfalls, lava flows, and avalanches. Infrasound observations will be further integrated with other data streams, such as seismic, ground- and satellite-based thermal and visual imagery, geodetic, lightning, and gas data. The volcano infrasound community should continue efforts to make data and codes accessible and to improve diversity, equity, and inclusion in the field. In summary, the next decade of volcano infrasound research will continue to advance our understanding of complex volcano processes through increased data availability, sensor technologies, enhanced modeling capabilities, and novel data analysis methods that will improve hazard detection and mitigation.

58 GEOSCIENCES↗

Subtask 1.3 – Integrated Carbon Capture and Storage for North Dakota Ethanol Production

The Energy & Environmental Research Center (EERC), in partnership with Red Trail Energy, LLC (RTE), a North Dakota ethanol producer; the North Dakota Industrial Commission (NDIC) Renewable Energy Program (REP); and the U.S. Department of Energy (DOE), conducted a feasibility and implementation study for a commercial carbon capture and storage (CCS) effort. This subtask provided technical support and developed recommended practices of how small-scale industrial CO2 emitters (<1,000,000 tonnes of CO2 emitted annually) may economically deploy CCS. The 64-million-gallon dry mill RTE ethanol facility, emitting an average 180,000 tonnes of CO2 annually, was the subject of the case study. The positive outcome of this research, which shows technical and economic potential for ethanol–CCS in North Dakota, has resulted in RTE acquiring an approved Permit to Drill on December 2, 2019, for a stratigraphic test well in early 2020, a necessary step toward a North Dakota CO2 Storage Facility Permit (SFP) for the RTE CCS effort. Outcomes include 1) validating the Broom Creek Formation as a regional target for CCS, 2) determining the full carbon life cycle of an industrial fuel production facility with CCS, 3) developing a field implementation plan (FIP) for small-scale CCS, and 4) determining the validity and pathway for using CCS to meet low-carbon fuel (LCF) standards. The technical team included the EERC, RTE, Trimeric Corporation, Schlumberger Carbon Services, and Computer Modelling Group (CMG). Findings from activities conducted November 2016 – May 2020 are summarized as follows. Several key steps have been accomplished toward validating the Broom Creek Formation as a CO2 injection and storage target at the RTE CCS site, including verification of the presence and structure of sandstone layers that may comprise the potential CO2 storage reservoir and the several thousand feet of overlying confining zone. Work included site characterization using existing data, interpretation of seismic data within the study area, and geologic modeling simulation of CO2 injection. Interpreted results estimate 3000 feet of confining zone between the Broom Creek Formation (storage target) and the lowermost underground source of drinking water (e.g., the Fox Hills Formation). The thickness of the Broom Creek injection target varies 230–420 ft within the survey area. Results were used to inform the location of a stratigraphic test well and associated characterization test program. No impediments were identified within the targeted CO2 storage complex that would prevent the project from moving forward. A stratigraphic test well is the next step to validate these results and to acquire remaining data necessary to develop a North Dakota CO2 SFP application. The EERC generated full carbon life cycle estimates for CCS integration with the RTE ethanol facility. Results indicated that an average 40% reduction in CO2 emissions is possible through CCS implementation. Approximately half of the carbon in the overall life cycle for a dry mill ethanol plant is generated through the fermentation process and emitted to the atmosphere; this is the CO2 stream targeted for CCS. The remaining carbon is attributed to corn feedstock farming (diesel, fertilizer), energy for fuel processing (natural gas, electricity), and transportation (diesel) of the fuel product. Life cycle carbon estimates are also affected by the anticipated energy consumption of a potential capture facility, which depend on the type of CO2 product generated. For example, a 30%–40% net CO2 emission reduction is estimated if a liquefied CO2 facility were incorporated compared to a 40%–50% net CO2 reduction if a supercritical “injection-grade” CO2 product is generated; i.e., more energy is required to further refine the CO2 stream, affecting the full carbon life cycle estimates. A CCS FIP was developed and initiated at the RTE CCS site, resulting in the development of several guidance documents: a CO2 Capture Process Design Package, a North Dakota CO2 geologic Storage Permits Template, and a Public Outreach Package for CCS in North Dakota. General FIP components include CO2 capture system, pipeline and well designs; monitoring, verification, and accounting (MVA) plans; geologic characterization and testing programs; and permitting and outreach plans. Vendor bids were also acquired for the CO2 liquefaction facility. Near-surface characterization (groundwater and soil gas sampling) and geologic characterization (seismic survey) were initiated to inform development of a UIC Class VI-compliant MVA plan compliant with a North Dakota CO2 SFP. Designs (well and geologic testing) were completed for a stratigraphic test well compliant with a North Dakota CO2 SFP. In addition, the outreach plan was executed, including community open houses, meetings with city/county/state officials, and development of public materials. Although other entities continued to mature incentive programs in 2019–2020, California and the Internal Revenue Service (IRS) currently provide the most advanced economic opportunities for CCS integrated with fuel production. The California Low-Carbon Fuel Standard (LCFS) adopted a CCS Protocol in January 2019, allowing submittal of a design-based pathway (DBP) application for an approved temporary (not certified) carbon intensity value for a fully engineered facility. An ethanol–CCS DBP application to the California LCFS Program (officially approved February 28, 2020) was developed to show that the RTE CCS effort meets LCFS requirements. The approved DBP provides confidence to advance the project and supports potential investments. Other entities continue to mature incentive programs. The IRS issued guidance in February 2020 that addresses the definition of beginning of construction and revenue procedure on partnerships for the Enhancement of Carbon Dioxide Sequestration Credit (a.k.a. Section 45Q) CCS tax credit program; the IRS anticipates issuing further guidance on issues such as secure geologic storage, utilization qualifications, and recapture of claimed credits. Maturing incentive programs coupled with workable permitting regulations provide confidence to advance CCS projects in North Dakota and support financial investment to proceed with designing, constructing, and implementing CCS projects at small-scale fuel production facilities. The largest hurdles for CCS implementation at small-scale industrial systems are often business/economic-related (i.e., not technical). Market uncertainty already exists for agriculture-based alternative fuels such as corn ethanol, for which production has increased by ~33%, and prices have correspondingly lowered since 2015. Passing the Section 45Q tax credit program improves economic feasibility for CCS but may require external investors for a small business to achieve maximum benefits. Public–private partnerships with NDIC and DOE have resulted in foundational technical and regulatory knowledge, growing stakeholder confidence, and a pathway to implementation that enables similar industrial CCS projects in the region to advance. This subtask was funded through the EERC–DOE Joint Program on Research and Development for Fossil Energy-Related Resources Cooperative Agreement No. DE-FE0024233. Nonfederal funding was provided by NDIC and RTE. The authors would also like to thank CMG, ESRI, IHS, Neuralog, and Schlumberger for allowing the use of their software packages in support of this work.

42 ENGINEERING↗

Real-time nuclear activation detectors for measuring neutron angular distributions at the National Ignition Facility (invited)

The Real Time Nuclear Activation Detector (RTNAD) array at NIF measures the distribution of 14 MeV neutrons emitted by deuterium-tritium (DT) fueled inertial confinement fusion implosions. The uniformity of the neutron distribution is an important indication of implosion symmetry and DT shell integrity. The array consists of 48 LaBr 3 (Ce) crystal gamma-ray spectrometers mounted outside the NIF target chamber, which continuously monitor the slow decay of the 909 keV gamma-ray line from activated 89 Zr located in Zr cups surrounding each crystal. The measured decay rate dramatically increases during a DT implosion in proportion to the number of 14 MeV neutrons striking each Zr cup. The neutrons produce activated 89 Zr through an (n, 2n) reaction on 90 Zr, which is insensitive to low energy neutrons. The neutron flux along the detector line-of-sight at shot time is determined by extrapolating the fitted 909 keV decay curve back to shot time. Automatic analysis algorithms were developed to handle the non-stop data stream. The large number of detectors and the high statistical accuracy of the array enable the spherical harmonic modes of the neutron angular distribution to be measured up to L ≤ 4 to provide a better understanding of implosion dynamics. In addition, these data combined with measurements of the down-scattered neutrons can be used to derive fuel areal density distributions. This paper will describe the RTNAD hardware and analysis procedures.

46 INSTRUMENTATION RELATED TO NUCLEAR SCIENCE AND ↗

Machine learning changes the rules for flux limiters

Learning to integrate non-linear equations from highly resolved direct numerical simulations has seen recent interest for reducing the computational load for fluid simulations. Here, we focus on determining a flux-limiter for shock capturing methods. Focusing on flux limiters provides a specific plug-and-play component for existing numerical methods. Since their introduction, an array of flux limiters has been designed. Using the coarse-grained Burgers' equation, we show that flux-limiters may be rank-ordered in terms of their log-error relative to high-resolution data. We then develop a theory to find an optimal flux-limiter and present flux-limiters that outperform others tested for integrating Burgers' equation on lattices with [Formula: see text], and 2x, 3x, 4x, and 8x coarse-grainings. We train a continuous piecewise linear limiter by minimizing the mean-squared misfit to six-grid point segments of high-resolution data, averaged over all segments. While flux limiters are generally designed to have an output of φ(r) = 1 at a flux ratio of r = 1, our limiters are not bound by this rule and yet produce a smaller error than standard limiters. Here we find that our machine learned limiters have distinctive features that may provide new rules-of-thumb for the development of improved limiters. Additionally, we use our theory to learn flux-limiters that outperform standard limiters across a range of values (as opposed to at a specific fixed value) of coarse-graining, number of discretized bins, and diffusion parameter. This demonstrates the ability to produce flux limiters that should be more broadly useful than standard limiters for general applications.

97 MATHEMATICS AND COMPUTING↗

Implementation of heterodyne detection of radio frequency waves using phase contrast imaging

An upgrade to the DIII–D phase contrast imaging (PCI) diagnostic for detection of radio frequency waves has been implemented using low-noise optical heterodyning. Electro-optical modulation allows detection of waves with frequencies up to 500 MHz with wide flexibility restricted only by the driver electronics, with continuous adjustability up to 100 MHz and fixed frequency drivers needed for higher frequencies. The PCI diagnostic images the line-integrated plasma density fluctuations and provides absolutely calibrated measurements with good wavenumber resolution.

Rost, J. C. [Massachusetts Institute of Technology↗

The evolution of analytical techniques for multiplex analysis of protein biomarkers

Introduction: The landscape of biomarker development has evolved with advanced analytical technologies, particularly affinity- and mass spectrometry-based techniques. These advancements have deepened our understanding of disease mechanisms, enabling the development of precise diagnostic tools and personalized medicine. Protein biomarkers, which play pivotal roles in biological processes, have become invaluable in diagnosing and monitoring diseases, aided by their presence in various biological samples and the availability of established detection methods. Areas covered: This review covers the role of protein biomarkers in clinical practice, the development and dimensionality of protein biomarkers, advancements in detection technologies, a comparison of these technologies, and future directions in biomarker discovery and disease mechanism elucidation. Expert opinion: Advances in biomarker technologies have the potential to transform diagnostics and personalized treatment but face challenges such as high costs and technical complexity. Enhancing reproducibility and integrating multi-omics approaches may offer better insights. In conclusion, the field should evolve toward high-throughput, automated methods, continuously adapting research, and clinical practices.

59 BASIC BIOLOGICAL SCIENCES↗

Weak-charge form-factor determination at the electron-ion collider

Determining the weak charge form factor, 𝐹 𝑊 ⁡(𝑄 2 ), of nuclei over a continuous range of momentum transfers, 0 ≲ 𝑄 2 ≲ 0.1 GeV 2 , is essential for mapping out the distribution of neutrons in nuclei. The neutron density distribution has significant implications for a broad range of areas, including studies of nuclear structure, neutron stars, and physics beyond the Standard Model. Currently, our knowledge of 𝐹 𝑊 ⁡(𝑄 2 ) comes primarily from fixed target experiments that measure the parity-violating asymmetry in coherent elastic electron-ion scattering. Fixed target experiments, such as CREX and PREX-1,2, have provided high-precision weak charge form factor extractions for the 48 Ca and 208 Pb nuclei, respectively. However, a major limitation of fixed target experiments is that they each provide data only at a single value of 𝑄 2 . With the proposed electron-ion collider (EIC) on the horizon, we explore its potential to impact the determination of the weak charge form factor. While it cannot compete with the precision of fixed target experiments, it can provide data over a wide and continuous range of 𝑄 2 values, and for a wide variety of nuclei. We show that with data corresponding to an integrated luminosity of ℒ ∼ 500/𝐴 fb −1 , where 𝐴 is the nucleus atomic weight, the EIC can significantly impact constraints by lifting degeneracies in theoretical models of the neutron density distribution. Ensuring EIC detector coverage at low 𝑄 2 and large negative pseudorapidities will be essential for such 𝐹 𝑊 ⁡(𝑄 2 ) measurements.

72 PHYSICS OF ELEMENTARY PARTICLES AND FIELDS↗

Oak Ridge National Laboratory Security by Design: A Plant Design and Component-Based Approach to Technical Solutions to Insider and Outsider Threat

Security costs for nuclear reactors have been shown to rise over the lifecycle of a nuclear facility as new threats, security weaknesses, and the generic threat profile of the plant location change over time. This paper conducts a review of the technological gaps that currently exist in Security by Design (SeBD) based on the literature available and attempts to close those gaps through proposing technological constructs and processes that can integrate safety and security in the design process of a plant, with a primary focus on SMR technology. Under the new modular and mass manufacturing regime, where plant designs attempt to reduce costs with potential economies of scale and modular construction, the current SeBD definitions focusing on state level regulators are not considered adequate since the licensing stage is often too late in the design process to integrate the true cost savings of SeBD. Thus, this paper attempts to remedy the current logic in order to allow for continuous implementation of security alongside the development of the safety concept for the plant. If adopted within the design process the establishment of this type of technology will allow for a technological ecosystem to evolve that will imbed security concepts into the physical design of the components of the plant.

22 GENERAL STUDIES OF NUCLEAR REACTORS↗

Innovative Subsurface Learning and Hawaiian Exploration using Advanced Tomography (ISLAND HEAT) Phase 1 (Final Report)

The Innovative Subsurface Learning and Hawaiian Exploration using Advanced Tomography (ISLAND HEAT) project aims to leverage and enhance existing Hawai'i geothermal play fairway analysis (PFA) results and validate a conceptual model-driven, optimized, least-cost exploration and geophysical suite at a proven geothermal field with known permeability, the Puna Geothermal Venture, located in the Lower East Rift Zone. The abundance of geophysical scrutinization before, during, and after the 2018 Kilauea eruption at and around the broader Puna system offers a rare opportunity to elucidate geophysical expressions within a dynamic magmatic rift setting. Development of the methodology continues with its application at a second prospective site identified by the PFA, Mauna Kea, which serves as confirmation of the integrated approach.

15 GEOTHERMAL ENERGY↗

Pipe-in-Pipe by Rapid, Continuous, Smart Alloy Coating

Our team has developed a comprehensive solution for performing in-situ structural repairs on metal piping and pipelines. This is based on a multifaceted and integrated (experimental and computational) approach, that uses a slurry-based coating and our patented high temperature sintering process, to build new metal in a pipe-in-pipe configuration. This can be utilized in either a complete pipe-in-pipe embodiment, or for patch repairs.

42 ENGINEERING↗

Rheo–Electric Foundations and Engineering of Carbon Slurry Flow Electrodes

Flowable carbon slurry electrodes promise continuous, scalable electrochemical desalination and energy storage when their rheology (flow and stability) and electronic connectivity are jointly optimized. This report integrates six complementary thrusts that we executed under the Laboratory Directed Research and Development (LDRD) project: (i) a fast, ex situ, centrifuge-compatible method to quantify pellet (packed slurry) electronic conductivity, with a validated cell constant (“shape factor”) and quantitative structure–property insights for carbon mixtures; (ii) a controlled circulation study showing that peristaltic pumping can irreversibly alter particle size and morphology over laboratory-relevant durations; (iii) development of a miniature jet pump that preserves particle integrity while achieving entrainment ratios of 2–4 at practical flow rates; (iv) a comprehensive mapping of how a representative non-ionic surfactant (Tween 20) collapses the carbon gel network, separating network-percolation losses from intrinsic particle contact resistance; (v) in-situ visualization revealing how gravitational settling and flow-driven mixing compete to control charge transport, with dynamic bed layers preventing saturation while achieving 30-fold local concentration enhancement; and (vi) a simple, widely adoptable fabrication route to structured, gas-nitrided titanium nitride (TiN) titanium current collectors that dramatically lower interfacial losses and enable geometry-driven performance gains. Together, these results provide a coherent toolchain and design rules to accelerate formulation screening, de-risk device prototyping, and standardize characterization for carbon slurry electrodes in flow-electrode capacitive deionization (FCDI), electrochemical flow capacitor (EFC), and related systems.

25 ENERGY STORAGE↗

Artificial Intelligence and Digital Engineering as Enablers for System Engineering in the Energy Sector

Systems engineering is of utmost importance for the success of high-cost, high-complexity megaprojects, which are common in the energy sector. However, the traditional document-centric systems engineering approach tends to be labor-intensive and time-consuming, which has inhibited its full adoption despite proven metrics on its return on investment. However, with the modern approach of digital engineering and technological advancements in artificial intelligence (AI) technologies, the barriers to systems engineering adoption can finally be broken. This paper goes through the systems engineering V-model for lifecycle management and assesses the current state of implementation of digital engineering (especially, mod-el-based systems engineering, digital twins, and digital threads) and AI for each step. It was observed that a combination of digital engineering and AI is being used across different industries to accelerate and optimize systems engineering processes such as concept development, requirements management, architecture definition, system development, verification and validation, operations, and maintenance. Specifically in the energy sector, AI-augmented digital engineering has shown initial potential in accelerated development and deployment, performance optimization, anomaly detection, predictive maintenance, and configuration management. However, challenges remain in integrating DE and AI into an end-to-end system lifecycle management ecosystem safely and reliably. Addressing these challenges and continuously developing impactful tools will enable fast, efficient, and high-frequency deployment of power generation capabilities to keep up with the world’s energy demands and build energy security.

42 - ENGINEERING↗

Artificial Intelligence and Digital Engineering as Enablers for Systems Engineering in the Energy Sector

Systems engineering is of utmost importance for the success of high-cost, high-complexity megaprojects, which are common in the energy sector. However, the traditional document-centric systems engineering approach tends to be labor-intensive and time-consuming, which has inhibited its full adoption despite proven metrics on its return on investment. However, with the modern approach of digital engineering and technological advancements in artificial intelligence (AI) technologies, the barriers to systems engineering adoption can finally be broken. This paper goes through the systems engineering V-model for lifecycle management and assesses the current state of implementation of digital engineering (especially, mod-el-based systems engineering, digital twins, and digital threads) and AI for each step. It was observed that a combination of digital engineering and AI is being used across different industries to accelerate and optimize systems engineering processes such as concept development, requirements management, architecture definition, system development, verification and validation, operations, and maintenance. Specifically in the energy sector, AI-augmented digital engineering has shown initial potential in accelerated development and deployment, performance optimization, anomaly detection, predictive maintenance, and configuration management. However, challenges remain in integrating DE and AI into an end-to-end system lifecycle management ecosystem safely and reliably. Addressing these challenges and continuously developing impactful tools will enable fast, efficient, and high-frequency deployment of power generation capabilities to keep up with the world?s energy demands and build energy security.

42 - ENGINEERING↗

Harnessing photoenzymatic reactions for unnatural biosynthesis in microorganisms

Photoenzymatic catalysis enables new-to-nature transformations, but its scalability is limited by high enzyme loading, costly cofactors, and radical-induced instability. Here we report the integration of light-driven photoenzymatic reactions into the cellular metabolism of Escherichia coli, bridging flavin-based photobiocatalysis with biosynthesis. Using synthetic biology strategies, we engineered microbial cells to continuously produce olefin substrates and ene-reductase photoenzyme while regenerating cofactors directly from glucose. By externally supplying radical precursors or by introducing synthetic pathways for their in situ production, we enabled fermentation-based microbial photobiosynthesis, achieving high titers and demonstrating its feasibility for scale-up in bioreactor. This approach extends photobiocatalysis from in vitro applications to in vivo semi-biosynthesis and complete biosynthesis, revealing its full potential for integrating light-driven reactions into cellular metabolism.

Bioproducts↗

End-of-Life Evaluation of Compressed Natural Gas Vehicle Fuel Tanks

This study evaluated the structural integrity of Type III and Type IV CNG fuel tanks from the Los Angeles (LA) County Metropolitan Transportation Authority to characterize the fuel tank conditions after experiencing a full service life of 15 years in transit bus application. The data produced provide insight about the condition of the CNG fuel tanks at the conclusion of their defined EOL and potential risks of continued operation of the CNG vehicle without replacement of the expired fuel tanks. In addition to physical testing performed on the fuel tanks, a nondestructive evaluation of modal acoustic emission (MAE) was utilized to assess the structural integrity of the tanks. The CNG fuel tanks were evaluated in their received condition and after experiencing artificial damage. The MAE results were then compared to visual inspection results of the procedures defined in the Compressed Gas Association’s (CGA’s) C-6.2 and C-6.4 standards (Compressed Gas Association 2013; 2012) to better understand the effectiveness of the visual inspection and potential safety risks of continued use of the tanks.

03 NATURAL GAS↗

Tunable White Light for Elders (TWLITE): A Protocol Demonstrating Feasibility and Acceptability for Deployment, Remote Data Collection, and Analysis of a Home-Based Lighting Intervention in Older Adults

Sleep disturbances are common in older adults and may contribute to disease progression in certain populations (e.g., Alzheimer’s disease). Light therapy is a simple and cost-effective intervention to improve sleep. Primary barriers to light therapy are: (1) poor acceptability of the use of devices, and (2) inflexibility of current devices to deliver beyond a fixed light spectrum and throughout the entirety of the day. However, dynamic, tunable lighting integrated into the native home lighting system can potentially overcome these limitations. Herein, we describe our protocol to implement a whole-home tunable lighting system installed throughout the homes of healthy older adults already enrolled in an existing study with embedded home assessment platforms (Oregon Center for Aging & Technology—ORCATECH). Within ORCATECH, continuous data on room location, activity, sleep, and general health parameters are collected at a minute-to-minute resolution over years of participation. This single-arm longitudinal protocol collected participants’ light usage in addition to ORCATECH outcome measures over a several month period before and after light installation. The protocol was implemented with four subjects living in three ORCATECH homes. Technical/usability challenges and feasibility/acceptability outcomes were explored. The successful implementation of our protocol supports the feasibility of implementing and integrating tunable whole-home lighting systems into an automated home-based assessment platform for continuous data collection of outcome variables, including long-term sleep measures. Challenges and iterative approaches are discussed. This protocol will inform the implementation of future clinical intervention trials using light therapy in patients at risk for developing Alzheimer’s disease and related conditions.

60 APPLIED LIFE SCIENCES↗

Analysis and Planning Framework for Nuclear Plant Transformation

Commercial nuclear power in the United States has been an unqualified success by any measure, providing low cost, carbon-free, and safe baseload electricity for decades. The industry today is at the peak of its historical performance in terms of generation output, reliable operations, and demonstrated nuclear safety. However, it is no longer among the lowest-cost electric generation sources with the emergence of subsidized renewables and shale gas generation. The business model that has served the operating nuclear fleet so well over its life is now a drag on cost performance due to its reliance on a large highly skilled labor force. In contrast, digital technology and innovation are enabling dramatic efficiencies in energy production, resulting in fierce competition for a commodity such as electricity. The nuclear power industry has responded to this challenge with many initiatives to improve efficiency and modernize plant equipment, especially where reliability and obsolescence issues are pressing. However, it would be a missed opportunity to merely modernize the plant components and the work processes of an outdated business model that was formulated to manage the technology of the 1960s. Rather, the greater opportunity is to transform that business model to one that fully exploits the capabilities of modern digital technology, resulting in substantially lower production costs and sustainable market viability. One successful example of such transformation is the concept of Integrated Operations, which was introduced into the North Sea oil and gas industry a couple of decades ago when the profitability of operating these fields was severely threatened by low world petroleum prices and the high overhead of operating the offshore oil and gas platforms. This effort resulted in significant changes to how these oil fields were operated and allowed the industry to continue profitable operation of these platforms. This example has some remarkable parallels to the U.S. commercial nuclear industry as described in the next section. This report provides an analysis and planning framework for such a nuclear plant operating model transformation based on the transferable learnings from the North Sea transformation. This framework is termed Integrated Operations for Nuclear or ION. This report describes the key principles and methods of Integrated Operations and how they are being applied in a collaboration between the DOE Light Water Reactor Sustainability Program and Xcel Energy in an initiative to transform its operating model for performance improvement and long-term sustainability. It describes a method to bring the operating costs of a nuclear fleet in line with market-based pricing, transforming work functions to reduce cost with technology innovations. This initiative will continue over the next several years in the detailed development of transformative concepts for nuclear plants, which will be published as follow-up to this initial report on Integrated Operations for Nuclear.

21 SPECIFIC NUCLEAR REACTORS AND ASSOCIATED PLANTS↗