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At least 595 records · Page 33

Evaluation of an active magnetic resonance tracking system for interstitial brachytherapy

Purpose: In gynecologic cancers, magnetic resonance (MR) imaging is the modality of choice for visualizing tumors and their surroundings because of superior soft-tissue contrast. Real-time MR guidance of catheter placement in interstitial brachytherapy facilitates target coverage, and would be further improved by providing intraprocedural estimates of dosimetric coverage. A major obstacle to intraprocedural dosimetry is the time needed for catheter trajectory reconstruction. Herein the authors evaluate an active MR tracking (MRTR) system which provides rapid catheter tip localization and trajectory reconstruction. The authors assess the reliability and spatial accuracy of the MRTR system in comparison to standard catheter digitization using magnetic resonance imaging (MRI) and CT. Methods: The MRTR system includes a stylet with microcoils mounted on its shaft, which can be inserted into brachytherapy catheters and tracked by a dedicated MRTR sequence. Catheter tip localization errors of the MRTR system and their dependence on catheter locations and orientation inside the MR scanner were quantified with a water phantom. The distances between the tracked tip positions of the MRTR stylet and the predefined ground-truth tip positions were calculated for measurements performed at seven locations and with nine orientations. To evaluate catheter trajectory reconstruction, fifteen brachytherapy catheters were placed into a gel phantom with an embedded catheter fixation framework, with parallel or crossed paths. The MRTR stylet was then inserted sequentially into each catheter. During the removal of the MRTR stylet from within each catheter, a MRTR measurement was performed at 40 Hz to acquire the instantaneous stylet tip position, resulting in a series of three-dimensional (3D) positions along the catheter’s trajectory. A 3D polynomial curve was fit to the tracked positions for each catheter, and equally spaced dwell points were then generated along the curve. High-resolution 3D MRI of the phantom was performed followed by catheter digitization based on the catheter’s imaging artifacts. The catheter trajectory error was characterized in terms of the mean distance between corresponding dwell points in MRTR-generated catheter trajectory and MRI-based catheter digitization. The MRTR-based catheter trajectory reconstruction process was also performed on three gynecologic cancer patients, and then compared with catheter digitization based on MRI and CT. Results: The catheter tip localization error increased as the MRTR stylet moved further off-center and as the stylet’s orientation deviated from the main magnetic field direction. Fifteen catheters’ trajectories were reconstructed by MRTR. Compared with MRI-based digitization, the mean 3D error of MRTR-generated trajectories was 1.5 ± 0.5 mm with an in-plane error of 0.7 ± 0.2 mm and a tip error of 1.7 ± 0.5 mm. MRTR resolved ambiguity in catheter assignment due to crossed catheter paths, which is a common problem in image-based catheter digitization. In the patient studies, the MRTR-generated catheter trajectory was consistent with digitization based on both MRI and CT. Conclusions: The MRTR system provides accurate catheter tip localization and trajectory reconstruction in the MR environment. Relative to the image-based methods, it improves the speed, safety, and reliability of the catheter trajectory reconstruction in interstitial brachytherapy. MRTR may enable in-procedural dosimetric evaluation of implant target coverage.

60 APPLIED LIFE SCIENCES↗

SU-G-JeP1-05: Clinical Impact of MLC Tracking for Lung SABR

Purpose: The objective of this study was to investigate the dosimetric benefits of multi-leaf collimator (MLC) tracking for lung SABR treatments in end-to-end clinically realistic planning and delivery scenarios. Methods: The clinical benefits of MLC tracking were assessed using previously delivered treatment plans and physical experiments. The 10 most recent single lesion lung SABR patients were re-planned following a 4D-GTV-based real-time adaptive protocol (PTV defined as the end-of-exhalation GTV plus 5.0 mm margins). The plans were delivered on a Trilogy Varian linac. Electromagnetic transponders (Calypso, Varian Medical Systems, USA) were embedded into a programmable moving phantom (HexaMotion platform) tracked with the Varian Calypso system. For each physical experiment, the MLC positions were collected and used as input for dose reconstruction. For both planned and physical experiments, the OAR dose metrics from the conventional and real-time adaptive SABR plans (Mean Lung Dose (MLD), V20 for lung, and near-maximum dose (D2%) for spine and heart) were statistically compared. The Wilcoxon test was used to compare plan and physical experiment dose metrics. Results: While maintaining target coverage, percentage reductions in dose metrics to the OARs were observed for both planned and physical experiments. Comparing the two plans showed MLD percentage reduction (MLDr) of 25.4% (absolute differences of 1.41 Gy) and 28.9% (1.29%) for the V20r. D2% percentage reduction for spine and heart were respectively 27.9% (0.3 Gy) and 20.2% (0.3 Gy). For the physical experiments, MLDr was 23.9% (1.3 Gy), and V20r 37.4% (1.6%). D2% reduction for spine and heart were respectively 27.3% (0.3 Gy) and 19.6% (0.3 Gy). For both plans and physical experiments, significant OAR dose differences (p<0.05) were found between the conventional SABR and real-time adaptive plans. Conclusion: Application of MLC tracking for lung SABR patients has the potential to reduce the dose to OARs during radiation therapy.

60 APPLIED LIFE SCIENCES↗

SU-G-JeP1-14: Respiratory Motion Tracking Using Kinect V2

Purpose: Investigate capability and accuracy of Kinect v2 camera for tracking respiratory motion to use as a tool during 4DCT or in combination with motion management during radiotherapy treatments. Methods: Utilizing the depth sensor on the Kinect as well as code written in C#, the respiratory motion of a patient was tracked by recording the depth (distance) values obtained at several points on the patient. Respiratory traces were also obtained using Varian’s RPM system, which traces the movement of a propriety marker placed on the patient’s abdomen, as well as an Anzai belt, which utilizes a pressure sensor to track respiratory motion. With the Kinect mounted 60 cm above the patient and pointing straight down, 11 breathing cycles were recorded with each system simultaneously. Relative displacement values during this time period were saved to file. While RPM and the Kinect give displacement values in distance units, the Anzai system has arbitrary units. As such, displacement for all three are displayed relative to the maximum value for the time interval from that system. Additional analysis was performed between RPM and Kinect for absolute displacement values. Results: Analysis of the data from all three systems indicates the relative motion obtained from the Kinect is both accurate and in sync with the data from RPM and Anzai. The absolute displacement data from RPM and Kinect show similar displacement values throughout the acquisition except for the depth obtained from the Kinect during maximum exhalation (largest distance from Kinect). Conclusion: By simply utilizing the depth data of specific points on a patient obtained from the Kinect, respiratory motion can be tracked and visualized with accuracy comparable to that of the Varian RPM and Anzai belt.

60 APPLIED LIFE SCIENCES↗

WE-H-BRA-08: A Monte Carlo Cell Nucleus Model for Assessing Cell Survival Probability Based On Particle Track Structure Analysis

Purpose: To correlate the damage produced by particles of different types and qualities to cell survival on the basis of nanodosimetric analysis and advanced DNA structures in the cell nucleus. Methods: A Monte Carlo code was developed to simulate subnuclear DNA chromatin fibers (CFs) of 30nm utilizing a mean-free-path approach common to radiation transport. The cell nucleus was modeled as a spherical region containing 6000 chromatin-dense domains (CDs) of 400nm diameter, with additional CFs modeled in a sparser interchromatin region. The Geant4-DNA code was utilized to produce a particle track database representing various particles at different energies and dose quantities. These tracks were used to stochastically position the DNA structures based on their mean free path to interaction with CFs. Excitation and ionization events intersecting CFs were analyzed using the DBSCAN clustering algorithm for assessment of the likelihood of producing DSBs. Simulated DSBs were then assessed based on their proximity to one another for a probability of inducing cell death. Results: Variations in energy deposition to chromatin fibers match expectations based on differences in particle track structure. The quality of damage to CFs based on different particle types indicate more severe damage by high-LET radiation than low-LET radiation of identical particles. In addition, the model indicates more severe damage by protons than of alpha particles of same LET, which is consistent with differences in their track structure. Cell survival curves have been produced showing the L-Q behavior of sparsely ionizing radiation. Conclusion: Initial results indicate the feasibility of producing cell survival curves based on the Monte Carlo cell nucleus method. Accurate correlation between simulated DNA damage to cell survival on the basis of nanodosimetric analysis can provide insight into the biological responses to various radiation types. Current efforts are directed at producing cell survival curves for high-LET radiation.

60 APPLIED LIFE SCIENCES↗

Study of performance of the ATLAS transition radiation tracker in run 1 of the LHC: Tracking characteristics

The ATLAS Transition Radiation Tracker (TRT) contains more than 350000 large straw tubes and it is the outermost of the three subsystems of the ATLAS Inner Detector (ID). The TRT contributes substantially to the ATLAS ID resolution for the tracks of high-energy particles, providing excellent particle identification capabilities and electron-pion separation. Basic performance parameters of the TRT related to its tracking function are described in this paper. The data used in this study were collected during the first period of the Large Hadron Collider (LHC) operation in 2012 with a proton collision energy of 8 TeV. The tracking performance of the TRT has been studied in the case of operating with a Xe-based gas mixture and as a function of the straw occupancy. Special attention was paid to investigation of tracking parameters inside hadronic jets. The experimental data and simulation are in reasonable agreement, even within the dense cores of the most energetic jets.

72 PHYSICS OF ELEMENTARY PARTICLES AND FIELDS↗

Solar Prize Round 5 Software Track: Abbreviated Final Technical Report

Solar Prize Round 5 launched two simultaneous tracks, the Hardware Track and the Software Track, to introduce software innovations into the Solar Prize for the first time. The primary goal of the prize is to accelerate the development, validation, and commercialization of innovative solar software solutions that will increase the competitiveness of the U.S. solar industry. This is accomplished with three escalating challenges, called the Ready!, Set!, and Go! Contests, where teams work to develop their concept from idea to potentially marketable product in less than one year. Competitors also have the option to compete in a Justice, Equity, Diversity, and Inclusion (JEDI) Contest, which recognizes solutions that enable underserved communities in the United States to overcome systemic solar barriers and share equitably in the societal benefits of solar deployment. The Prize concluded by awarding 2 final winners the Go! Contest prize and a 3rd winner to the JEDI Contest prize in the Software Track, after competing in the prize for a year and demonstrating their success through each phase.

14 SOLAR ENERGY↗

Latent Tracks in Ion-Irradiated LiTaO 3 Crystals: Damage Morphology Characterization and Thermal Spike Analysis

Systematic research on the response of crystal materials to the deposition of irradiation energy to electrons and atomic nuclei has attracted considerable attention since it is fundamental to understanding the behavior of various materials in natural and manmade radiation environments. This work examines and compares track formation in LiTaO3 induced by separate and combined effects of electronic excitation and nuclear collision. Under 0.71–6.17 MeV/u ion irradiation with electronic energy loss ranging from 6.0 to 13.8 keV/nm, the track damage morphologies evolve from discontinuous to continuous cylindrical zone. Based on the irradiation energy deposited via electronic energy loss, the subsequently induced energy exchange and temperature evolution processes in electron and lattice subsystems are calculated through the inelastic thermal spike model, demonstrating the formation of track damage and relevant thresholds of lattice energy and temperature. Combined with a disorder accumulation model, the damage accumulation in LiTaO3 produced by nuclear energy loss is also experimentally determined. The damage characterizations and inelastic thermal spike calculations further demonstrate that compared to damage-free LiTaO3, nuclear-collision-damaged LiTaO3 presents a more intense thermal spike response to electronic energy loss owing to the decrease in thermal conductivity and increase in electron–phonon coupling, which further enhance track damage.

36 MATERIALS SCIENCE↗

Using Fission-Track Radiography Coupled with Scanning Electron Microscopy for Efficient Identification of Solid-Phase Uranium Mineralogy at a Former Uranium Pilot Mill (Grand Junction, Colorado)

At a former uranium pilot mill in Grand Junction, Colorado, mine tailings and some subpile sediments were excavated to various depths to meet surface radiological standards, but residual solid-phase uranium below these excavation depths still occurs at concentrations above background. The combination of fission-track radiography and scanning electron microscope energy-dispersive X-ray spectroscopy (SEM-EDS) provides a uniquely efficient and quantitative way of determining mineralogic associations of uranium that can influence uranium mobility. After the creation of sample thin sections, a mica sheet is placed on those thin sections and irradiated in a nuclear research reactor. Decay of the irradiated uranium creates fission tracks that can be viewed with a microscope. The fission-track radiography images indicate thin section sample areas with elevated uranium that are focus areas for SEM-EDS work. EDS spectra provide quantitative elemental data that indicate the mineralogy of individual grains or grain coatings associated with the fission-track identification of elevated uranium. For the site in this study, the results indicated that uranium occurred (1) with coatings of aluminum–silicon (Al/Si) gel and gypsum, (2) dispersed in the unsaturated zone associated with evaporite-type salts, and (3) sorbed onto organic carbon. The Al/Si gel likely formed when low-pH waters were precipitated during calcite buffering, which in turn retained or precipitated trace amounts of Fe, As, U, V, Ca, and S. Understanding these mechanisms can help guide future laboratory and field-scale efforts in determining long-term uranium release rates to groundwater.

58 GEOSCIENCES↗

Search for GeV and X-Ray Flares Associated with the IceCube Track-like Neutrinos

Dozens of high-energy neutrinos have been detected by the IceCube neutrino telescope, but no clear association with any classes of astrophysical sources has been identified so far. Recently, Kadler et al. reported that a PeV cascade-like neutrino event occurred in positional and temporal coincidence with a giant gamma-ray flare of the blazar PKS B1424-418. Since IceCube track-like events have much better angular resolution, we here search for possible short-term gamma-ray flares that are associated with the IceCube track-like events with Fermi Large Area Telescope (LAT) observations. Among them, three track-like neutrino events occur within the field of view of Fermi -LAT at the time of the detection, so searching for the prompt gamma-ray emission associated with neutrinos is possible. Assuming a point source origin and a single power-law spectrum for the possible gamma-ray sources associated with neutrinos, a likelihood analysis of 0.2–100 GeV photons observed by Fermi -LAT on the timescales of ∼12 hr and one year are performed, and for the three special neutrinos, the analyses are also performed on the timescales of thousands of seconds before and after the neutrino detection. No significant GeV excesses over the background are found and upper limit fluxes at the 95% confidence level are obtained for different timescales. We also search for possible the Swift hard X-ray transient sources associated with the IceCube track-like neutrino events, but the search also yields null results. We discuss the implication of the non-detection of gamma-ray flares for the constraints on the neutrino source density.

79 ASTRONOMY AND ASTROPHYSICS↗

Biomimetic Fly Eye Sensor for Real-Time Target Tracking

The project objective is to design, build, and demonstrate a biomimetic (inspired by biology) smart sensor based on the common house fly eye for real-time target tracking in three dimensions (3-D). The sensor makes use of revolutionary optical sensor design resulting in significantly improved motion detection capabilities when compared with conventional optical sensors. The design is motivated by the parallel nature of the flys vision system and its demonstrated hyperacuity or precision of visual localization beyond the conventional resolution limit. This means that the sensor is able to accurately detect very fast motion and small changes in motion. The analog architecture of the sensor allows for real-time solution at adjustable bandwidths depending on the application. The low cost, exceptionally lightweight, small form factor, low power requirements, and low computation requirements of the sensor make it ideally suited to many aeronautics applications that have limitations on weight, power, and processing time. The sensor is modular and can be easily adapted in scale and manufactured for a wide variety of sensing applications. Advanced target tracking algorithms will be developed to allow the sensor to track a target in 3-D. These algorithms will be implemented in the smart sensors hardware to enable real-time target tracking.

wing position measurement system↗

A Simulated Fire Edge Vis-IR Detection and Tracking Approach for Autonomous sUAS in STEReO

This study presents a fire edge detection and tracking methodology for an autonomous small UAS (sUAS). The sUAS, onboard sensors, and wildfire are simulated to evaluate the methodology. A visible light (Vis) camera and an infrared (IR) camera are simulated onboard the sUAS to identify burnt, burning, and unburnt areas on a static wildfire bitmap. After differentiating between these areas, a form of nonlinear guidance law (NLGL) is used to generate virtual target points (VTP) that guide the sUAS so that the fire edge is kept within the camera FOV. The VTP are passed to the sUAS flight management system (FMS) in the form of waypoints. The approach was tested in simulation and demonstrated tracking curved, sharp, and linear fire edge shapes at different altitudes. Higher altitude tracking proved to demand the least control effort without sacrificing continuous tracking.

Autonomous UAV↗

Limitations on the Use of Eye-Tracking Data to Understand Operator Awareness

Safety events in commercial aviation have implicated failures of attention and awareness, and the need for improved attention and awareness has pushed trainers toward eye-tracking systems as a primary tool for evaluating monitoring performance. Further, in the last 15 years, eye-tracking technology has become easier to acquire and use in operationally realistic settings. Although we believe that eye-tracking can be a useful evaluation tool, this paper describes basic limitations on relying on eye-tracking as the sole means for evaluating attention and awareness. A set of other measures are offered that can better identify where performance breakdowns occur.

aviation↗

Differences in total stem value when merchandizing with a tracked processor versus a knuckle–boom loader in Pinus taeda

Using tracked processors over knuckle–boom loaders to increase total value per tree when merchandizing timber on the landing has become a topic of interest in the southeastern region of the United States. This study compared merchantability values, product classes, and product weights of loblolly pine (Pinus taeda) for both machines to determine if there was a significant difference between machines when processing the same tree. In order to process the same tree twice, the chains from the tracked processor had to be removed from the bottom saw bar. This allowed the processor to simulate the merchandising process without actually marking or cutting the tree for a more realistic comparison. Data were analyzed using paired t–tests and two–way ANOVA models. Results depicted that when diameter and total lengths are visually estimated by the knuckle–boom loader. A significant difference in value occurs, however, once diameter and total length are modified to match the tracked processors for more accurate measurements, no difference in value was seen. Here, these results demonstrate that until mill specifications become more stringent, there is little incentive for loggers to purchase a tracked processor if their only motivation is to increase merchantability values.

42 ENGINEERING↗

Development of a Computational Framework for Multiphysics Multiphase Species Tracking using NEAMS Tools

This report implements a high-fidelity multiphysics modeling framework using the Nuclear Energy Advanced Modeling and Simulation (NEAMS) program tools to track isotopic species in Molten Salt Reactors (MSRs), with a specific focus on the 91-depletion chain within the Molten Salt Reactor Experiment (MSRE). The model integrates neutronics, thermal-hydraulics, depletion, and thermochemistry to simulate the production, transport, and phase transitions of isotopes under steady-state and transient conditions. The main findings reveal that isotopes such as bromine-91 largely remain in the liquid phase, while others, including krypton-91and yttrium-91, transition to the gas phase, significantly influencing the reactor’s radiological source term. The study also shows that during transients, like a reactivity insertion transient, rapid void formation and the expansion of the liquid-gas interface led to substantial transfers of dissolved isotopes into the gas phase, altering isotope distribution and largely increasing the source term in the off-gas system. Additionally, the research highlights that short-lived isotopes dominate the initial off-gas response during transients, while longer-lived isotopes determine the equilibrium state, underscoring the necessity of dynamic simulations for accurate species tracking and reactor safety analysis. The developed methodology will be applied in the future to the tracking of a larger number of species and introduce other species tracking mechanisms, such as deposition and plating.

11 NUCLEAR FUEL CYCLE AND FUEL MATERIALS↗

Motion Tracking Above and Below Water Dataset

This data set includes one trial of above and under water motion tracking measurements from a Qualysis motion tracking system. The Qualisys native .qtm file can be opened by the Qualisys Track Manager software. Data from this file has been exported to a tab separated value (.tsv) file which is a generic ASCII file format that can be read by a text editor, MATLAB, Excel, etc... Also exported is a native MATLAB formatted file (.mat) which can be loaded directly into MATLAB. The trial is from a three body wave energy converter device, using the underwater system for the central nacelle data, and above water system for the fore and aft floats.

16 TIDAL AND WAVE POWER↗

Search for disappearing tracks as a signature of new long-lived particles in proton-proton collisions at $ \sqrt{s}=13 $ TeV

Here, a search is presented for long-lived charged particles that decay within the CMS detector and produce the signature of a disappearing track. A disappearing track is an isolated track with missing hits in the outer layers of the silicon tracker, little or no energy in associated calorimeter deposits, and no associated hits in the muon detectors. This search uses data collected with the CMS detector in 2015 and 2016 from proton-proton collisions at a center-of-mass energy of 13 TeV at the LHC, corresponding to an integrated luminosity of 38.4 fb$^{-1}$. The results of the search are interpreted in the context of the anomaly-mediated supersymmetry breaking model. The data are consistent with the background-only hypothesis. Limits are set on the product of the cross section for direct production of charginos and their branching fraction to a neutralino and a pion, as a function of the chargino mass and lifetime. At 95% confidence level, charginos with masses below 715 (695) GeV are excluded for a lifetime of 3 (7) ns, as are charginos with lifetimes from 0.5 to 60 ns for a mass of 505 GeV. These are the most stringent limits using a disappearing track signature on this signal model for chargino lifetimes above $\approx$0.7 ns.

72 PHYSICS OF ELEMENTARY PARTICLES AND FIELDS↗

Precision inclusive Higgs physics at e+e- colliders with tracking detectors and without calorimetry

A primary goal of a future e + e - collider program will be the precision measurement of Higgs boson properties. For practical reasons it is of interest to determine the minimal set of detector specifications required to reach this and other scientific goals. Here we investigate the precision obtainable for the e + e - Zh μ + μ - X inclusive cross section and the Higgs boson mass using the di-muon recoil method, considering a detector that has only an inner tracking system within a solenoidal magnetic field, surrounded by many nuclear interaction lengths of absorbing material, and an outer muon identification system. We find that the sensitivity achievable in these measurements with such a tracking detector is only marginally reduced compared to that expected for a general purpose detector with additional electromagnetic and hadronic calorimeter systems. The difference results mainly from multi-photon backgrounds that are not as easily rejected with tracking detectors. We also comment on the prospects for an analogous measurement of the e + e - → Zh → e + e - X inclusive cross section. Finally, we study searches for light scalars utilizing the di-muon recoil method, estimating the projected reach with a tracking or general purpose detector.

71 CLASSICAL AND QUANTUM MECHANICS, GENERAL PHYSIC↗

Dot tracking methodology for background-oriented schlieren (BOS)

We propose here a dot tracking methodology for processing background-oriented schlieren (BOS) images. The technique improves the accuracy, precision and spatial resolution compared to conventional cross-correlation algorithms. Our methodology utilizes the prior information about the dot pattern such as the location, size and number of dots to provide near 100% yield even for high dot densities (20 dots/32 × 32 pixels) and is robust to image noise. Furthermore, we propose an improvement to the displacement estimation step in the tracking process, especially for noisy images, using a “correlation correction”, whereby we combine the spatial resolution benefit of the tracking method and the smoothing property of the correlation method to increase the dynamic range of the overall measurement process. We evaluate the performance of the method with synthetic BOS images of buoyancy-driven turbulence rendered using ray-tracing simulations, and experimental images of flow in the exit plane of a converging–diverging nozzle. The results show that the improved spatial resolution results in a better accuracy of the tracking method compared to correlation-based methods in regions with sharp displacement gradients, and the correlation correction step reduces the noise floor of the measurement, resulting in a fourfold improvement in the dynamic range.

42 ENGINEERING↗