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At least 595 records · Page 33

Review of internal and external surface finishing technologies for additively manufactured metallic alloys components and new frontiers

Surface finishing in additive manufacturing (AM) is a technological bottleneck. The field of surface finishing of AM parts is vast because it not only focuses on roughness reduction in the hard-to-access internal surfaces but also includes the scope of adding coatings and sensors. Even though metal AM component is reaching the density and bulk microstructure at par or even better than conventionally produced components, adverse impact of surface roughness and imperfections is becoming the major obstruction. It is observed that external and internal surface roughness of AM components is a high probability cause of many unavoidable issues such as corrosion, incorrect tolerance estimations during the build stage, and the fatigue failure of parts before the expected life cycle. At present, AM field mainly focuses on improving and enhancing the internal and external surface roughness to pass the stringent qualification requirements for actual applications. To address these challenges, researchers worldwide are conducting many experiments and developing different surface finishing techniques. This paper reviews the state-of-the-art knowledge and processes of different surface finishing technology that can be applied to AM metal components. This article mainly highlights several liquid-based surfaces finishing approaches to develop promising surface microstructures on interior and exterior surfaces as a micromachining tool. The future of making strong and self-monitoring AM component requires broadening of surface finishing field and including advanced topics such as coatings and adding sensor technology. We also discuss new frontiers and the scope of future work in the surface finishing field to bring attention to related concerns and possibilities associated with making smart and strong AM components for twenty-first-century integrated engineering systems.

36 MATERIALS SCIENCE↗

Thermodynamic and experimental assessment of proton conducting solid oxide fuel cells with internal methane steam reforming

Operating proton conducting solid oxide fuel cells (H-SOFCs) with hydrocarbon as fuel remains a challenge because of the instability of the anode and electrolyte materials in a CO 2 /H 2 O-containing atmosphere and the catalytic activity and coking resistance of the anode for direct oxidation of hydrocarbons. Therefore, in this paper, the steam reforming of methane (SRM, an endothermic process) is integrated into the H-SOFCs (fuel cell process, an exothermic process) for internally converting hydrocarbon to hydrogen and increasing energy efficiency of H-SOFCs. Moreover, a proton-conducting zirconate oxide (BaZr 0.8 Y 0.2 O 3 , BZY), which is stable in a CO 2 /H 2 O-containing atmosphere, is applied as an electrolyte and anode material of H-SOFCs. The operation of BZY-based H-SOFCs with internal SRM is assessed by thermodynamic calculation and experiments for the first time. The catalytic activity and coking resistance of the Ni-BZY anode for SRM are investigated thermodynamically and experimentally. Finally, the results demonstrate that the Ni-BZY anode possesses reasonable catalytic activity as well as good coking resistance for SRM at a temperature as low as 550 °C. Then, the electrochemical performance and durability of H-SOFCs operated with internal SRM are comprehensively studied from 550 °C to 700 °C.

25 ENERGY STORAGE↗

Refining internal bilayer structure of bicelles resolved by extended-q small angle X-ray scattering

The internal profile across the bilayer reveals important structural information regarding the crystallinity of acyl chains or the positions of encapsulated species. Here, we demonstrate that a simple five-layer-core-shell discoidal model can be employed tobest fit the extended-qsmall angle X-ray scattering (SAXS) data and resolvethe bilayer internal structure (with sub-nanometer resolution) of a nanoscale discoidal system comprised of a mixture of long-and short-chain lipids(known as “bicelles”). In contrast to the traditional core-shell discoidal model, the detailed structure in the hydrophobic core such as the methylene and methyl groups can be distinguished via this model. The refined model is validated by the SAXS data of bicelles whose electron scattering length density of the hydrophobic core is adjusted by the addition of a long-chain lipid with a fluorine-end group.The higher resolution of the bilayer internal structure can be employed to advance our understanding of the interaction and conformation of the membrane and associated molecules, such as membrane-associated proteins and locations of entrapped species in the lipid nanoparticles.

36 MATERIALS SCIENCE↗

Topology optimization of additively manufactured fluidic components free of internal support structures

This report integrates projection-based approaches for implementing overhang constraints with fluid topology optimization to design additively manufactured fluidic components that do not require internal support structures. Internal support structures are challenging, potentially impossible to remove in complex fluid networks, yet would degrade fluidic performance if left within the part. This presents a major challenge in coupling topology optimization with additive manufacturing in the design of fluid components. The proposed approach leverages past work in overhang constraints for solid mechanics, including projection formulations and adjoint sensitivity analysis, and considers incompressible Navier–Stokes equations for laminar fluid flow. The approach is demonstrated on 2D and 3D fluid topology optimization problems to minimize pressure drop and constrain mass flow rates in pipes and manifolds. Resulting designs are crisp, logical, satisfy performance constraints, and satisfy overhang constraints, eliminating the need for internal support structures.

42 ENGINEERING↗

Internal and near nozzle measurements of Engine Combustion Network “Spray G” gasoline direct injectors

Gasoline direct injection (GDI) sprays are complex multiphase flows. When compared to multi-hole diesel sprays, the plumes are closely spaced, and the sprays are more likely to interact. The effects of multi-jet interaction on entrainment and spray targeting can be influenced by small variations in the mass fluxes from the holes, which in turn depend on transients in the needle movement and small-scale details of the internal geometry. In this paper, we present a comprehensive overview of a multi-institutional effort to experimentally characterize the internal geometry and near-nozzle flow of the Engine Combustion Network (ECN) Spray G gasoline injector. In order to develop a complete picture of the near-nozzle flow, a standardized setup was shared between facilities. A wide range of techniques were employed, including both X-ray and visible-light diagnostics. The novel aspects of this work include both new experimental measurements, and a comparison of the results across different techniques and facilities. The breadth and depth of the data reveal phenomena which were not apparent from analysis of the individual data sets. We show that plume-to-plume variations in the mass fluxes from the holes can cause large-scale asymmetries in the entrainment field and spray structure. Both internal flow transients and small-scale geometric features can have an effect on the external flow. The sharp turning angle of the flow into the holes also causes an inward vectoring of the plumes relative to the hole drill angle, which increases with time due to entrainment of gas into a low-pressure region between the plumes. In conclusion, these factors increase the likelihood of spray collapse with longer injection durations.

33 ADVANCED PROPULSION SYSTEMS↗

DECOVALEX-2019: An international collaboration for advancing the understanding and modeling of coupled thermo-hydro-mechanical-chemical (THMC) processes in geological systems

The DECOVALEX Project is an international research collaboration for advancing the understanding and modeling of coupled thermo-hydro-mechanical-chemical (THMC) processes in geological systems. DECOVALEX stands for “DEvelopment of COupled Models and VALidation against EXperiments”. The creation of this international initiative, now running for almost 30 years, was motivated by the recognition that prediction of these coupled effects is an essential part of the performance and safety assessment of geologic disposal systems for radioactive waste and spent nuclear fuel, and also for a range of other sub-surface engineering activities. DECOVALEX emphasizes joint analysis and comparative modeling of state-of-the-art field and laboratory experiments, across a range of host rock options and repository designs. Participating research teams are from radioactive waste management organizations, national research institutes, regulatory agencies, universities, and consulting groups, providing a wide range of perspectives and solutions to these complex problems. The most recent phase of the DECOVALEX Project, here referred to as DECOVALEX-2019, started in 2016 and ended in 2019. Modeling teams from 13 international partner organizations participated in the comparative evaluation of seven modeling tasks involving complex field and/or laboratory experiments. Furthermore, this Virtual Special Issue on DECOVALEX-2019 provides an in-depth overview of these collaborative research efforts and how these have advanced the state-of-the-art of understanding and modeling coupled THMC processes.

58 GEOSCIENCES↗

Modern Radiation Therapy for Hodgkin Lymphoma: Field and Dose Guidelines From the International Lymphoma Radiation Oncology Group (ILROG)

Radiation therapy (RT) is the most effective single modality for local control of Hodgkin lymphoma (HL) and an important component of therapy for many patients. These guidelines have been developed to address the use of RT in HL in the modern era of combined modality treatment. The role of reduced volumes and doses is addressed, integrating modern imaging with 3-dimensional (3D) planning and advanced techniques of treatment delivery. The previously applied extended field (EF) and original involved field (IF) techniques, which treated larger volumes based on nodal stations, have now been replaced by the use of limited volumes, based solely on detectable nodal (and extranodal extension) involvement at presentation, using contrast-enhanced computed tomography, positron emission tomography/computed tomography, magnetic resonance imaging, or a combination of these techniques. The International Commission on Radiation Units and Measurements concepts of gross tumor volume, clinical target volume, internal target volume, and planning target volume are used for defining the targeted volumes. Newer treatment techniques, including intensity modulated radiation therapy, breath-hold, image guided radiation therapy, and 4-dimensional imaging, should be implemented when their use is expected to decrease significantly the risk for normal tissue damage while still achieving the primary goal of local tumor control. The highly conformal involved node radiation therapy (INRT), recently introduced for patients for whom optimal imaging is available, is explained. A new concept, involved site radiation therapy (ISRT), is introduced as the standard conformal therapy for the scenario, commonly encountered, wherein optimal imaging is not available. There is increasing evidence that RT doses used in the past are higher than necessary for disease control in this era of combined modality therapy. The use of INRT and of lower doses in early-stage HL is supported by available data. Although the use of ISRT has not yet been validated in a formal study, it is more conservative than INRT, accounting for suboptimal information and appropriately designed for safe local disease control. The goal of modern smaller field radiation therapy is to reduce both treatment volume and treatment dose while maintaining efficacy and minimizing acute and late sequelae. This review is a consensus of the International Lymphoma Radiation Oncology Group (ILROG) Steering Committee regarding the modern approach to RT in the treatment of HL, outlining a new concept of ISRT in which reduced treatment volumes are planned for the effective control of involved sites of HL. Nodal and extranodal non-Hodgkin lymphomas (NHL) are covered separately by ILROG guidelines.

62 RADIOLOGY AND NUCLEAR MEDICINE↗

External Validation and Optimization of International Consensus Clinical Target Volumes for Adjuvant Radiation Therapy in Bladder Cancer

Purpose: International consensus (IC) clinical target volumes (CTVs) have been proposed to standardize radiation field design in the treatment of patients at high risk of locoregional failure (LRF) after radical cystectomy. The purpose of this study was to externally validate the IC CTVs in a cohort of postsurgical patients followed up for LRF and identify revisions that might improve the IC CTVs' performance. Methods and Materials: Among 334 patients with pT3 to pT4 bladder cancer treated with radical cystectomy, LRF developed in 58 (17%), of whom 52 had computed tomography scans available for review. Images with LRF were exported into a treatment planning system, and IC CTVs were contoured and evaluated for adequacy of coverage of each LRF with respect to both the patient and each of 6 pelvic subsites: common iliac (CI) region, obturator region (OR), external and internal iliac region, presacral region, cystectomy bed, or other pelvic site. Revisions to the IC contours were proposed based on the findings. Results: Of the 52 patients with documented LRF, 13 (25%) had LRFs that were outside of the IC CTV involving 17 pelvic subsites: 5 near the CI CTV, 5 near the OR CTV, 1 near the external and internal iliac region, and 6 near the cystectomy bed. The 5 CI failures were located superior to the CTV, and the 5 OR failures were located medial to the CTV. Increasing the superior boundary of the CI to a vessel-based definition of the aortic bifurcation, as well as increasing the medial extension of the OR by an additional 9 mm, decreased the number of patients with LRF outside of the IC CTV to 7 (13%). Conclusions: Modified IC CTVs inclusive of a slight adjustment superiorly for the CI region and medially for the OR may reduce the risk of pelvic failure in patients treated with adjuvant radiation therapy.

62 RADIOLOGY AND NUCLEAR MEDICINE↗

Phase II testing of Xenon International on Mount Schauinsland, Germany

Station RN33 on Mount Schauinsland near Freiburg, Germany, is part of the International Monitoring System monitoring radioxenon in air ( 131m Xe, 133 Xe, 133m Xe, and 135 Xe) for verification of the Comprehensive Nuclear Test Ban Treaty. Here, we present data from phase II testing of a new system, Xenon International at RN33, July 14th, 2021 to Jan 22nd, 2022, together with SPALAX data from the same time period. Radioxenon could be detected in 473 of 719 samples, among them many multiple isotope detections. Activity concentrations of spiked and selected environmental samples were verified by laboratory reanalysis. Finally, the sensitivity of Xenon International for radioxenons is up to one order of magnitude better for the metastable isotopes than that of the SPALAX, with a shorter sampling duration of 6 h.

98 NUCLEAR DISARMAMENT, SAFEGUARDS, AND PHYSICAL P↗

Characterization of zirconium carbide microspheres synthesized via internal gelation

Microspheres of zirconium carbide with grain size 40-320 nm were synthesized using internal gelation techniques and characterized by scanning electron microscopy, synchrotron X-ray diffraction, and neutron total scattering. Compared with a polycrystalline benchmark ZrC sample prepared by plasma vapor phase deposition, the microspheres display lower variance in grain size and considerably lower microstrain representative of a more homogenous internal microstructure. However, excess carbon was present in the microspheres, evident in both the X-ray and neutron diffraction data as well as a corresponding hypostoichiometric ZrC phase. Furthermore, the excess carbon phase is assumed to be pockets of carbon that remained unreacted through the combined internal gelation and subsequent carbothermic reduction synthesis process. Atomic-scale structural characterization with neutron PDF analysis confirmed the presence of localized nano-sized domains of graphite-like carbon material.

36 MATERIALS SCIENCE↗

Internal influences of hydrolysis conditions on rutile TiO2 pigment production via short sulfate process

Highlights: • A novel short sulfate process was proposed to produce rutile TiO{sub 2} pigment. • Effects and internal influences of hydrolysis conditions were investigated in detail. • Intrinsic relationship between hydrolysis conditions and pigment properties were revealed. - Abstract: Rutile TiO{sub 2} white pigment was prepared via short sulfate process by using the unenriched industrial TiOSO{sub 4} solution as titanium source through authigenic seed hydrolysis process. The effects and internal influences of hydrolysis conditions on the structure, particle size distribution and pigment properties for the as-synthesized samples were investigated, involving the inducing hydrolysis water volume ratio, ripening time and hydrolysis time after the second boiling point. These hydrolysis factors influenced the number and quality of the initial formed hydrolysis nuclei, the crystal growth and the particle aggregation velocity, eventually determined the pigment properties. And the conditions had internal mathematical regression correlation with crystal structure, particle polydispersity index and pigment properties. The optimal inducing hydrolysis water volume ratio is of 0.123, ripening time is of 29.05 min, and hydrolysis time is of 2.6 h.

75 CONDENSED MATTER PHYSICS, SUPERCONDUCTIVITY AND↗

High Critical Current Density in Internally-oxidized Nb 3 Sn Superconductors and its Origin

In this paper, we report achievement of non-Cu-matrix critical current density $(J_c)$ in internally-oxidized Nb 3 Sn superconductors that surpasses the best state-of-the-art Nb 3 Sn and the $J_c$ specification of the Future Circular Collider. We then explore the mechanism of the improvement, which was believed to be caused by refined grain size. However, our experiment showed that even with similar grain size, internally-oxidized wires had significantly higher $J_c$ than non-oxidized wires. This, combined with transmission electron microscopy and atom probe tomography studies which showed a high density of intragranular nano-precipitates with suitable sizes as pinning centers in internally-oxidized wires, demonstrates a significant contribution from the nano-precipitates.

43 PARTICLE ACCELERATORS↗

CXCR3 expression in colorectal cancer cells enhanced invasion through preventing CXCR4 internalization

Highlights: • Colon cancer cells with both CXCR3 and CXCR4 expression showed significantly stronger invasive phenotype. • In CRC cells, CXCR3 prevented CXCR4 internalization through forming heteromers with CXCR4 on cell surface. • CXCR3-A, instead of CXCR3-B, was mainly responsible for inhibited CXCR4 internalization and enhanced cell invasion. • CRC cells with both CXCR3 and CXCR4 expression showed more metastasis in mice lung tissue after intravenously injections. One of the major causes of death in colorectal cancer (CRC) is invasion and metastasis. Better understanding of the molecular mechanism of CRC invasion and metastasis is essential in developing effective cancer therapies. Cooperative effect of CXCR3 and CXCR4 plays a crucial role in regulating CRC invasion. In present study, we discovered that CRC cells expressing higher levels of CXCR3 and CXCR4 were more invasive. Additionally, CXCR3 formed heteromers with CXCR4 and retained CXCR4 on cell surface. CXCR3 knockdown reduced surface CXCR4 expression and partially inhibited CRC cell invasion. On the contrary, CXCR3 overexpression enhanced surface CXCR4 abundance and promoted CRC cell invasion. Further research indicated that CXCR3-A isoform was responsible for increased CXCR4 surface expression and CRC cell invasion. However, CXCR3-A overexpression without CXCR4 expression did not cause CRC cell invasion, which suggested that CXCR3-A indirectly affect cell invasion through regulating CXCR4. Taken together, CXCR3 enhanced CXCR4 function in CRC cell invasion through forming heteromers with CXCR4 on cell surface and prevent CXCR4 internalization. Therefore, targeting CXCR3 could be a promising strategy for clinical treatment of CRC cell invasion and metastasis.

60 APPLIED LIFE SCIENCES↗

Internal wave energy flux from density perturbations in nonlinear stratifications

Internal gravity wave energy contributes significantly to the energy budget of the oceans, affecting mixing and the thermohaline circulation. Hence it is important to determine the internal wave energy flux $\boldsymbol{J}=p\,\boldsymbol{v}$ , where $p$ is the pressure perturbation field and $\boldsymbol{v}$ is the velocity perturbation field. However, the pressure perturbation field is not directly accessible in laboratory or field observations. Previously, a Green’s function based method was developed to calculate the instantaneous energy flux field from a measured density perturbation field $\unicode[STIX]{x1D70C}(x,z,t)$ , given a constant buoyancy frequency $N$ . Here we present methods for computing the instantaneous energy flux $\boldsymbol{J}(x,z,t)$ for an internal wave field with vertically varying background $N(z)$ , as in the oceans where $N(z)$ typically decreases by two orders of magnitude from the pycnocline to the deep ocean. Analytic methods are presented for computing $\boldsymbol{J}(x,z,t)$ from a density perturbation field for $N(z)$ varying linearly with $z$ and for $N^{2}(z)$ varying as $\tanh (z)$ . To generalize this approach to arbitrary $N(z)$ , we present a computational method for obtaining $\boldsymbol{J}(x,z,t)$ . The results for $\boldsymbol{J}(x,z,t)$ for the different cases agree well with results from direct numerical simulations of the Navier–Stokes equations. Our computational method can be applied to any density perturbation data using the MATLAB graphical user interface ‘EnergyFlux’.

Mechanics↗

Antagonistic Growth Effects of Mercury and Selenium in Caenorhabditis elegans Are Chemical-Species-Dependent and Do Not Depend on Internal Hg/Se Ratios

The relationship between mercury (Hg) and selenium (Se) toxicity is complex, with coexposure reported to reduce, increase, and have no effect on toxicity. Different interactions may be related to chemical compound, but this has not been systematically examined. Our goal was to assess the interactive effects between the two elements on growth in the nematode Caenorhabditis elegans, focusing on inorganic and organic Hg (HgCl2 and MeHgCl) and Se (selenomethionine, sodium selenite, and sodium selenate) compounds. We utilized aqueous Hg/Se dosing molar ratios that were either above, below, or equal to 1 and measured the internal nematode total Hg and Se concentrations for the highest concentrations of each Se compound. Observed interactions were complicated, differed between Se and Hg compounds, and included greater-than-additive, additive, and less-than-additive growth impacts. Biologically significant interactions were only observed when the dosing Se solution concentration was 100–25 000 times greater than the dosing Hg concentration. Mitigation of growth impacts was not predictable on the basis of internal Hg/Se molar ratio; improved growth was observed at some internal Hg/Se molar ratios both above and below 1. These findings suggest that future assessments of the Hg and Se relationship should incorporate chemical compound into the evaluation.

54 ENVIRONMENTAL SCIENCES↗

DFT Analysis of the Binding of Rare Earth Nitrates at Internal and External Surfaces of MCM-22

MCM-22-type zeolites constitute a well-characterized tunable class of aluminosilicates suitable for elucidating the fundamental aspects of the binding of rare earth elements (REEs) in layered materials. Starting from the pure silica version ITQ-1 with a unit cell of Si 72 O 144 , a model for periodic bulk crystalline MCM-22 with a finite Al concentration is provided by replacing a Si atom with an Al atom in the unit cell at suitable tetrahedral sites near an internal pore surface. Then, a H atom is added to an O atom bridging Si and Al atoms to create a Brønsted acid site (BAS). There are no internal silanol groups in this bulk model. To generate a model for an external surface, we adopt the fully hydroxylated surface structure of a layer within the ITQ-1 precursor with two silanols per lateral unit cell. A BAS on the external surface can be generated by replacing a near-surface Si atom with an Al atom and adding a H atom, as above. The strength of binding at a BAS of REE, X, taken to be present in the solution phase as nitrates, is determined from the energy change in the reaction X(NO 3 ) 3 + ≡Si–{OH}–Al≡ → ≡Si–{OX(NO 3 ) 2 }–Al≡+ HNO 3 . The strength of binding at the silanols is determined similarly. Binding energies are determined from two approaches. The first performs periodic plane-wave density functional theory (DFT) total energy analysis for an entire unit cell of MCM-22. The second utilizes cluster models capturing the local environment of REE binding sites and performs DFT analysis with localized basis sets. The two approaches yield consistent results for Nd, revealing similarly strong binding at either an external or internal BAS, but much weaker binding at a silanol site. This is consistent with the picture deduced from recent experiments. Here, we also comment on binding at Al-bridged siloxane sites, which have been suggested as alternative binding sites to BAS.

37 INORGANIC, ORGANIC, PHYSICAL, AND ANALYTICAL CH↗

Contributions of Internal Variability and External Forcing to the Recent Pacific Decadal Variations

Abstract There is substantial uncertainty in the relative contributions of internal variability and external forcing to the recent Pacific decadal variability, especially regarding their linkage with the Interdecadal Pacific Oscillation. By analyzing observations and large ensembles of coupled climate model simulations, here we show that observed Pacific decadal variations since 1920 resulted primarily from internal variability, although greenhouse gas (GHG) and other external forcing did modulate decadal variations in Pacific sea surface temperatures (SSTs) significantly, especially for the period since the early 1990s. Specifically, the GHG‐induced warming and the recovery from the volcanic cooling caused by the 1991 Pinatubo eruption led to large warming in the tropical Pacific during 1993–2012, while recent anthropogenic aerosols contributed to Pacific regional SST variations on multiyear to decadal scales, causing a La Niña‐like cooling pattern in the Pacific since 1998 in some of the models. Our results provide new evidence that both internal variability and external forcing have contributed to the recent decadal variations in Pacific SSTs since the early 1990s, although large uncertainties exist among the model‐simulated effects of anthropogenic aerosols.

54 ENVIRONMENTAL SCIENCES↗

Baroclinic Residual Circulation and Mass Transport Due to Internal Tides

Baroclinic (BC) tidal residual circulation due to internal tides is investigated around islands over a shallow ridge using a numerical ocean model. Internal tides enhance vertical mixing over shallow slopes, leading to horizontal density gradients that drive BC residual circulation along the main thermocline. For a strongly stratified summer case, the vertical diffusivity estimated by the Mellor and Yamada turbulence closure model exceeds 1 × 10 -2 m 2 s -1 , and the velocity of BC residual circulations reaches 0.2 m s -1 . The magnitude of BC residual circulation is larger than that of barotropic residual tidal circulation, implying that BC residual circulation due to internal tides plays an important role in coastal ocean circulation. Furthermore, BC residual flow accounts for an equal percentage (5%) of the total tidal kinetic energy as the barotropic residual flow under summer stratification conditions. Results from a coupled sediment resuspension and transport model show the growth of intermediate nepheloid layers formed by strong bottom shear stress and BC residual flow. The residual component contributes largely (23% of the total in summer) to the total suspended sediment flux. Seasonal variability is explored, with weaker winter stratification leading to reduced mixing, and thus weaker BC residual circulation and sediment flux. Lastly, the magnitude of the BC residual circulation is also shown to be proportional to the square of the tidal amplitude.

54 ENVIRONMENTAL SCIENCES↗